Cuntooyinka loogu talagalay Cudurka Paget Extramammary!

Hordhac

Cuntooyinka loogu talagalay cudurka bogagga aan caadiga ahayn waa in loo gaaryeelaa qof kasta oo waa in sidoo kale la qabsado marka daaweynta kansarka ama hidda-socodka buradu ay isbeddelaan. Shakhsiyaynta iyo la qabsiga waa in ay tixgelisaa dhammaan maaddooyinka firfircoon ama bioactives ee ku jira cuntooyinka kala duwan marka loo eego bayooloojiyada unugyada kansarka, genetics, daawaynta, xaaladaha qaab nololeedka iyo doorbidka cuntada. Sidaa darteed iyadoo nafaqadu ay tahay mid ka mid ah go'aamada aadka muhiimka u ah bukaanka kansarka iyo qofka halista ugu jira kansarka inuu sameeyo - sida loo doorto cuntooyinka uu cuno maaha hawl fudud.

Cudurka 'Extramammary Paget's disease, kansarka maqaarka naadirka ah kaas oo sida caadiga ah saameeya meelaha ay ku badan yihiin qanjidhada apocrine, waxay soo bandhigaan caqabado gaar ah oo ku saabsan ogaanshaha iyo daaweynta. Xaaladdan waxay ku dhici kartaa ragga iyo dumarka labadaba, iyada oo dhacdooyinka la taaban karo ee xubinta taranka haweenka iyo xubnaha taranka ama xuubka xuubka ee ragga. Tilmaamaha pathology ee cudurka naas-nuujinta ka baxsan ee Paget ayaa bixiya aragtiyo muhiim ah oo ku saabsan sifooyinka gacanta iyo caawinta hagayaasha go'aamada daaweynta. Daawaynta sida caadiga ah waxay ku lug leedahay goynta qaliinka, iyo xaaladaha qaarkood, daawaynta jirka la mariyo ama shucaaca ayaa laga yaabaa in la tixgeliyo. Koodhka ICD-10 ee cudurka Paget ee ka baxsan naasaha ayaa fududeeya ka warbixinta iyo dabagalka daawaynta. DermNet iyo ilaha kale ee maqaarka ayaa bixiya macluumaad qiimo leh oo ku saabsan soo bandhigida kiliinikada iyo maaraynta cudurka. Halka cudurka Paget ee ka baxsan naasnuujintu uu ugu horrayn u saameeyo maqaarka, saadaasha uu leeyahay iyo su'aasha ah inuu u dhimanayo waxay ku xidhan tahay dhawr arrimood, oo ay ku jiraan jiritaanka cudur faafa ama xumaanta hoose. Naadirka cudurka Paget ee ka baxsan naas-nuujinta waxay ku kordhisaa kakanaanta barashada iyo fahamka, taas oo ka dhigaysa mawduuc cilmi-baaris joogto ah. Marka la soo koobo, maaraynta waxtarka leh ee cudurka Paget ee ka baxsan caanaha waxay u baahan tahay faham buuxa oo ku saabsan pathology-giisa, tixgelin taxaddar leh oo xulashooyinka daawaynta, iyo ka warqabka darnaanta suurtagalka ah, gaar ahaan xaaladaha horumarsan ama soo duulista.

Cudurka Paget Extramammary miyay muhiim u tahay khudaarta, miraha, lawska, miraha la cuno?

Su'aasha nafaqeynta ee aadka u badan ee ay weydiiyaan bukaannada kansarka iyo shakhsiyaadka halista ugu jira hidde-sidaha kansarka waa - kansarka sida Extramammary Paget Disease miyay muhiim tahay cuntooyinka aan cuno iyo kuwa aanan samayn? Mise haddii aan raaco cunto ku salaysan geedka waa taas ku filan kansarka sida Extramammary Paget Disease?

Tusaale ahaan miyay muhiim tahay haddii Karootada khudaarta la isticmaalo in ka badan marka la barbar dhigo Spinach Malabar? Miyay wax farqi ah samaynaysaa haddii midhaha Black Elderberry laga doorbido Evergreen Blackberry? Sidoo kale haddii xulashooyin la mid ah loo sameeyo nuts/abuurka sida Walnut-ka Jabbaan oo ka sarreeya Chestnut Yurub iyo garaaca sida digir-indho-madow oo ka sarreeya digirta caadiga ah. Oo haddii waxa aan cunaa ay arrintu khusayso - markaa sidee qofku u aqoonsan karaa cuntooyinka lagu taliyay Cudurka Paget Extramammary oo ma isku jawaabaa qof kasta oo leh isla cudurka ama khatarta hidde-sidaha?

Haa! Cuntooyinka aad cuntid ayaa arrimaha u ah Cudurka Paget Extramammary!

Talooyinka cuntadu waxay noqon karaan kuwo isku mid ah qof kasta oo way ka duwanaan karaan xitaa ogaanshaha isku midka ah iyo khatarta hidda-socodka.

Dhammaan cuntooyinka ( khudaarta, miraha, lawska, iniinaha, garaaca, saliidaha iwm.) iyo kaabayaasha nafaqadu waxay ka kooban yihiin wax ka badan hal walxo molecular ama bio-actives oo qiyaas iyo tiro kala duwan leh. Walax kasta oo firfircooni waxay leedahay hab u gaar ah oo wax qabad - kaas oo noqon kara firfircooni ama xannibaadda dariiqyada biochemical ee kala duwan. Cuntooyinka si fudud loo sheegay iyo kaabisyada lagu taliyay waa kuwa aan keenin korodhka wadayaasha molecular ee kansarka laakiin la yareeyo. Haddii kale cuntooyinkaas waa inaan lagu talin. Cuntooyinka waxaa ku jira maaddooyin badan oo firfircoon - markaa marka la qiimeynayo cuntooyinka iyo kaabayaasha waxaad u baahan tahay inaad tixgeliso saameynta dhammaan maaddooyinka firfircoon si wadajir ah halkii aad ka ahaan lahayd mid gaar ah.

Tusaale ahaan Black Elderberry waxaa ku jira maaddooyin firfircoon Curcumin, Daidzein, Formononetin, Cinnamaldehyde, Melatonin. Evergreen Blackberry waxaa ku jira maaddooyin firfircoon Ellagic Acid, Cinnamaldehyde, Eugenol, Myricetin, Linalool iyo kuwo kale oo suurtagal ah.

Qalad caadi ah oo la sameeyo marka la go'aaminayo oo la dooranayo cuntooyinka la cuno ee Cudurrada Paget Extramammary - waa in la qiimeeyo oo kaliya maaddooyinka firfircoon ee la doortay ee ku jira cuntooyinka oo la iska indhatiro inta kale. Sababtoo ah maaddooyinka kala duwan ee firfircoon ee ku jira cuntooyinka ayaa laga yaabaa inay saameyn iska soo horjeeda ku yeeshaan darawalada kansarka - ma qaadan kartid maaddooyinka firfircoon ee cuntooyinka iyo kaabayaasha si loo gaaro go'aanka nafaqada ee Cudurka Paget Extramammary.

HAA – DOORASHOOYINKA CUNTADA EE KANSARKA WAXAY U TAAGAN YAHAY. GO'AANKA NAFAQADA waa in ay tixgeliyaan dhammaan walxaha firfircoon ee CUNTADA.

Xirfadaha Looga Baahan Yahay Nafaqaynta Shakhsiyaynta Ee Cudurka Paget Extramammary?

Nafaqada shakhsi ahaaneed ee kansarrada sida Extramammary Paget Disease waxa ay ka kooban tahay cuntooyin/kaabyo lagu taliyey; Cuntooyinka aan lagu talin/kabka tusaale ahaan cunto karinta kuwaas oo mudnaanta siiya isticmaalka cuntooyinka lagu taliyay. Tusaale nafaqeynta gaarka ah ayaa tan lagu arki karaa link.

Go'aaminta cuntooyinka lagu taliyay iyo kuwa aan lagu talin waa mid aad u dhib badan, waxay u baahan tahay khibrad ku saabsan bayoolajiga cudurka Paget Extramammary, sayniska cuntada, genetics, biochemistry oo ay weheliso faham wanaagsan oo ku saabsan sida daawaynta kansarku u shaqeyso iyo baylahda la xidhiidha kuwaas oo daaweyntu ay joojin karto waxtarka.

Khibradda UGU YAR EE AQOONTA EE LOO BAAHAN YAHAY NAFAQADA SHAQSIYADEEDKA KANSARKA WAA: NOLOLIGA KANSARKA, CUNTADA CUNTADA, DAAWAYNTA KANSARKA IYO HIDDAHA HIDDAHA.

Astaamaha kansarka sida Extramammary Paget Disease

Dhammaan kansarrada sida Extramammary Paget Disease waxaa lagu sifeyn karaa qaybo gaar ah oo ah dariiqooyin kiimikaad - dariiqooyinka saxiixa ee Cudurka Paget Extramammary. Dariiqooyin kiimikaad sida PI3K-AKT-MTOR Calaamadaynta, Calaamadaynta Sababta Kobaca, Dib-u-habaynta Chromatin, Calaamadaynta MAPK waa qayb ka mid ah qeexida saxeexa Cudurka Paget Extramammary. Hidde-sideyaasha kansarku qof walba wuu ka duwanaan karaa sidaas darteed saxiixooda gaarka ah ee kansarku wuxuu noqon karaa mid gaar ah.

Daawaynta waxtarka u leh Cudurka Paget Extramammary waxay u baahan yihiin inay ogaadaan dariiqooyinka biochemical ee la xidhiidha saxeexa bukaan kasta oo kansar ah iyo shakhsi ahaan khatarta hidde-sidaha. Sidaa darteed daawayn kala duwan oo leh habab kala duwan oo ficil ah ayaa waxtar u leh bukaanada kala duwan. Si la mid ah iyo sababo la mid ah cuntooyinka iyo kaabista waxay u baahan yihiin in shaqsi kasta loo gaaryeelo. Sidaa awgeed cuntooyinka iyo kaabista qaar ayaa lagula taliyaa Cudurka Paget Extramammary marka la qaadanayo daawaynta kansarka Pazopanib, iyo cuntooyinka qaarkood iyo kaabista laguma talinayo.

Ilaha sida cBioPortal iyo qaar kale oo badan ayaa bixiya xogta bukaan-socodka ee aan la magacaabin ee laga helay tijaabooyinka bukaan-socodka ee dhammaan calaamadaha kansarka. Xogtan waxay ka kooban tahay tafaasiisha daraasadda tijaabada caafimaad sida cabbirka saamiga / tirada bukaannada, kooxaha da'da, jinsiga, qowmiyadda, daawaynta, goobta burooyinka iyo isbeddellada hidde-sidaha.

ERBB2, PPP2R1A iyo SMARCA4 waa hiddo-wadaha la soo sheegay ee ugu sarreeya ee cudurka Paget Extramammary. ERBB2 waxaa lagu soo warramey 33.3 % bukaannada matala dhammaan tijaabooyinka bukaan-socodka. PPP2R1A waxaa lagu soo warramey 33.3 %. Isku darka xogta bukaanka ee dadweynaha ayaa daboolaya da'aha laga bilaabo ilaa . 50.0 % xogta bukaanka waxaa loo aqoonsaday inay yihiin rag. Biology-ga Cudurka Paget Extramammary oo ay weheliso hidde-sideyaasha la soo sheegay ayaa si wada jir ah u qeexaya dariiqooyinka biochemical ee saxeexa dadweynaha ee kansarkan. Haddii genetics-ka burada kansarka shakhsi ahaaneed ama hiddo-wadaha ka qaybqaata khatarta sidoo kale waa la yaqaan markaa waa in sidoo kale loo isticmaalo shakhsiyaynta nafaqada.

Dookhyada nafaqeynta waa in ay iswaafaqaan shaqsi walba saxiixiisa.

Cunnada iyo Kaabayaasha Cudurrada Paget Extramammary

Bukaanka Kansarka

Bukaanjiifka kansarka ee ku jira daawaynta ama daryeelka palliative waxay u baahan yihiin inay go'aan ka gaadhaan cuntada iyo kaabista - kaloriinta cuntada ee loo baahan yahay, maaraynta waxyeellooyin kasta oo daawaynta iyo sidoo kale hagaajinta maaraynta kansarka. Dhammaan cuntooyinka dhirta ku salaysan maaha kuwo siman oo doorashada iyo kala horraysiinta cuntooyinka kuwaas oo shakhsi ahaan loo habeeyey oo loo habeeyey daawaynta kansarka ee socota waa muhiim oo dhib badan. Waa kuwan tusaalayaal siinaya tilmaamo lagu samaynayo go'aannada nafaqada.

Dooro KAARROT khudaar ah ama isbinaajka MALABAR?

Karootada khudradda leh waxay ka kooban tahay waxyaabo badan oo firfircoon ama bioactives sida Curcumin, Gamma-linolenic Acid, Daidzein, Formononetin, Cinnamaldehyde. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida PI3K-AKT-MTOR Signaling iyo kuwa kale. Karootada waxaa lagula taliyaa Cudurka Paget Extramammary marka daawaynta kansarka ee socota ay tahay Pazopanib. Tani waa sababta oo ah Karootada ayaa wax ka beddeleysa dariiqyada biochemical ee si cilmiyeysan loo soo sheegay si loo dareemo saameynta Pazopanib.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee khudradda Malabar Spinach waa Curcumin, Daidzein, Formononetin, Cinnamaldehyde, Melatonin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida PI3K-AKT-MTOR Signaling iyo kuwa kale. Spinach-ka Malabar laguma talinayo Cudurka Paget Extramammary marka daawaynta kansarka ee socota ay tahay Pazopanib sababtoo ah waxay wax ka beddeshaa dariiqyada biochemical ee ka dhigaya daaweynta kansarku mid adkaysi u leh ama aan ka jawaabin.

Karootada khudaarta ayaa lagula taliyaa in ka badan isbinaajka MALABAR oo loogu talagalay cudurka iyo daawaynta bogag aan caadi ahayn Pazopanib.

Dooro midho weligii cagaarka ahaa ama ODEYGA MADOW?

Miraha Evergreen Blackberry waxaa ku jira waxyaabo badan oo firfircoon ama bioactives sida Ellagic Acid, Cinnamaldehyde, Eugenol, Myricetin, Linalool. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida PI3K-AKT-MTOR Signaling iyo kuwa kale. Evergreen Blackberry waxaa lagula talinayaa Cudurka Paget Extramammary marka daawaynta kansarka ee socota ay tahay Pazopanib. Tani waa sababta oo ah Evergreen Blackberry waxay wax ka beddeshaa dariiqyada biochemical ee si cilmiyeysan loo soo sheegay si loo dareemo saameynta Pazopanib.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee ku jira miro Black Elderberry waa Curcumin, Daidzein, Formononetin, Cinnamaldehyde, Melatonin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida PI3K-AKT-MTOR Signaling iyo kuwa kale. Black Elderberry laguma talinayo Cudurka Paget Extramammary marka daawaynta kansarka ee socota ay tahay Pazopanib sababtoo ah waxay wax ka beddeshaa dariiqyada biochemical ee ka dhigaya daawaynta kansarku mid adkaysi u leh ama aan ka jawaabin.

Miraha weligii cagaarka ahaa ee madowga ah waxaa lagula taliyaa ODEYSIGA MADOW EE CUDURKA Paget-ka aan caadiga ahayn iyo daawaynta Pazopanib.

Dooro Walxaha JAPAN ee WALNUT ama XABADAHA YURUB?

Walnut-ka Jabbaan waxa ku jira maaddooyin badan oo firfircoon ama bioactives sida Curcumin, Ellagic Acid, Daidzein, Cinnamaldehyde, Formononetin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida PI3K-AKT-MTOR Signaling iyo kuwa kale. Walnut-ka Jabbaan waxa lagula taliyaa Cudurka Paget Extramammary marka daawaynta kansarka ee socota ay tahay Pazopanib. Tani waa sababta oo ah Walnut Japanese waxay wax ka beddeshaa dariiqyada biochemical ee si cilmiyeysan loo soo sheegay si loo dareemo saameynta Pazopanib.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee Chestnut Yurub waa Curcumin, Ellagic Acid, Daidzein, Cinnamaldehyde, Formononetin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida PI3K-AKT-MTOR Signaling iyo kuwa kale. Chestnut Yurub laguma talinayo Cudurka Paget Extramammary marka daawaynta kansarka ee socota ay tahay Pazopanib sababtoo ah waxay wax ka beddeshaa dariiqyada biochemical ee ka dhigaya daaweynta kansarku mid adkaysi u leh ama ka jawaabi kara.

WALNUT JAPAN AYAA LAGU TALAGALAY XANUUNKA YURUB OO LAGU TALAGALAY CUDURKA Paget-ka Aan Caadiga Ahayn iyo daawaynta Pazopanib.

Shakhsiyaadka leh Khatarta Hidde ee Kansarka

Su'aasha ay weydiiyaan shakhsiyaadka leh khatarta hidde-sidaha ee Cudurka Paget Extramammary ama taariikhda qoysku waa "Maxaan Cunnaa si ka duwan kii hore?" iyo sida ay tahay inay doortaan cuntooyinka iyo kaabista si loo maareeyo khatarta cudurka. Maadaama khatarta kansarku aanay jirin wax la qaban karo marka la eego daawaynta - go'aamada cuntooyinka iyo kaabista ayaa noqda mid muhiim ah iyo mid ka mid ah waxyaallaha aadka u yar ee la qaban karo. Dhammaan cuntooyinka dhirta ku salaysan maaha kuwo siman oo ku salaysan hidde-sidaha la aqoonsaday iyo saxeexa dariiqa - doorashooyinka cuntada iyo kaabista waa in la shakhsiyeeyo.

Dooro khudradda cusub ee ZEALAND isbinaajka ama CUCURBITA?

Khudaarta New Zealand Spinach waxay ka kooban tahay waxyaabo badan oo firfircoon ama bioactives sida Curcumin, Apigenin, Delphinidin, Quercetin, Lycopene. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida MAPK Signaling, Fospholipase Signaling, Calaamadaynta Sababta Kobaca iyo Calaamadaynta MYC iyo kuwa kale. Isbinaajka New Zealand waxaa lagula taliyaa halista Cudurka Paget Extramammary marka khatarta hidde-sidaha la xiriirta ay tahay ERBB2. Tani waa sababta oo ah Spinach New Zealand waxay kordhisaa dariiqyada biochemical ee ka soo horjeeda wadayaasha saxiixa.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee khudradda Cucurbita waa Curcumin, Delphinidin, Daidzein, Lupeol, Formononetin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida MYC Signaling iyo PI3K-AKT-MTOR Signaling iyo kuwa kale. Cucurbita laguma talinayo marka halista cudurka Paget Extramammary marka khatarta hidde-sidaha lala xiriiriyo ay tahay ERBB2 sababtoo ah waxay kordhisaa dariiqyada saxiixa.

Qudaarta NEW ZEALAND isbinaajka ayaa lagula talinayaa CUCURBITA oo loogu talagalay khatarta hidda-socodka ERBB2 ee kansarka.

Dooro Miraha BILBERRY ama PUMMELO?

Khudradu waxay ka kooban tahay waxyaabo badan oo firfircoon ama bioactives sida Curcumin, Apigenin, Delphinidin, Quercetin, Lycopene. Maaddooyinkan firfircooni waxay wax ka qabtaan dariiqooyin kiimikaad oo kala duwan sida MAPK Signaling, Isbaarada Wareegga Unugyada, Calaamadaynta Fosfolipase iyo Calaamadaynta MYC iyo kuwa kale. Bilberry waxaa lagula taliyaa halista Cudurka Paget Extramammary marka khatarta hidde-sidaha la xiriirta ay tahay ERBB2. Tani waa sababta oo ah Bilberry waxay kordhisaa dariiqyada biochemical ee ka soo horjeeda wadayaasha saxeexa.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee ku jira miro Pummelo waa Curcumin, Apigenin, Delphinidin, Naringenin, Hesperetin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida isbaarada wareegga unugyada iyo Epithelial ilaa Mesenchymal Transition iyo kuwa kale. Pummelo laguma talinayo marka halista cudurka Paget Extramammary marka khatarta hidde-sidaha la xidhiidha ay tahay ERBB2 sababtoo ah waxay kordhisaa dariiqooyinka saxeexa.

FRUIT BILBERRY ayaa lagula talinayaa PUMMELO oo loogu talagalay khatarta hidda-socodka ERBB2 ee kansarka.

Dooro Nut COMMON HAZELNUT ama LAABKA?

Hazelnut-ka caadiga ah waxa ku jira maaddooyin badan oo firfircoon ama bioactives sida Curcumin, Delphinidin, Quercetin, Lycopene, Daidzein. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida MAPK Signaling, Fospholipase Signaling, Calaamadaynta Sababta Kobaca iyo Calaamadaynta MYC iyo kuwa kale. Hazelnut-ka caadiga ah ayaa lagula taliyaa halista Cudurka Paget Extramammary marka khatarta hidde-sidaha la xiriirta ay tahay ERBB2. Tani waa sababta oo ah Hazelnut Common waxay kordhisaa dariiqyada biochemical ee ka soo horjeeda wadayaasha saxeexa.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee ku jira Chestnut waa Curcumin, Ellagic Acid, Apigenin, Delphinidin, Lycopene. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida isbaarada wareegga unugyada iyo Epithelial ilaa Mesenchymal Transition iyo kuwa kale. Chestnut laguma talinayo marka halista cudurka Paget Extramammary marka khatarta hidda-socodka lala xiriiriyo ay tahay ERBB2 sababtoo ah waxay kordhisaa dariiqyada saxiixa.

HAZELNUT caam ah ayaa lagula talinayaa laabta si looga hortago khatarta hidda-socodka ee ERBB2.

In Gabagabo

Cuntooyinka iyo Kaabayaasha la doortay waa go'aamo muhiim u ah kansarka sida Cudurka Paget Extramammary. Bukaannada ku jira Paget Extramammary Paget iyo shakhsiyaadka leh khatarta hidde-sidaha waxay had iyo jeer qabaan su'aashan: "Waa maxay cuntooyinka iyo kaabayaasha nafaqeynta ee lagu taliyay aniga iyo kuwa aan ahayn?" Waxaa jira aaminsanaan guud oo ah fikrad khaldan oo ah in dhammaan cuntooyinka dhirta ku salaysan ay faa'iido yeelan karaan ama aysan ahayn laakiin aan waxyeello lahayn. Cuntooyinka qaarkood iyo kaabisyada qaarkood waxay faragelin karaan daawaynta kansarka ama waxay kor u qaadi karaan wadayaasha dariiqyada molecular ee kansarka.

Waxaa jira noocyo kala duwan oo tilmaamayaasha kansarka sida Extramammary Paget Disease, mid kasta oo leh hidde-sidaha burooyinka oo kala duwan oo leh kala duwanaansho genomic dheeraad ah oo qof kasta ah. Intaa waxaa dheer daawaynta kansar kasta iyo kiimoterabi kasta waxay leeyihiin hab wax-qabad oo gaar ah. Cunto kasta sida Karootada oo kale waxa ay ka kooban tahay tirooyin kala duwan oo noole noolayaal ah, kuwaas oo saamayn ku leh noocyo kala duwan oo kala duwan oo ah dariiqyada biochemical. Qeexida nafaqeynta shakhsi ahaaneed waa talooyinka cuntada ee gaarka ah ee tilmaamaya kansarka, daawaynta, genetics, qaab nololeedka iyo arrimo kale. Go'aannada shakhsiyaynta nafaqada ee kansarka waxay u baahan yihiin aqoonta bayoolajiga kansarka, sayniska cuntada iyo fahamka daaweynta kemotherabi ee kala duwan. Ugu dambeyntii marka ay jiraan isbeddel daaweyn ama genomics cusub ayaa la aqoonsaday - shakhsiyeynta nafaqeynta waxay u baahan tahay dib-u-qiimeyn.

Xalka shakhsiyaynta nafaqeynta ee addon ayaa ka dhigaysa go'aan qaadashada mid fudud oo meesha ka saaraysa dhammaan mala-awaalka ka jawaabaya su'aasha, "Cunto noocee ah ayaan dooran karaa ama ma dooran karaa Cudurka Paget Extramammary?". Kooxda edbinta badan ee addon waxaa ka mid ah dhakhaatiirta kansarka, saynisyahano caafimaad, injineerada software iyo saynisyahano xogta.

tixraacyada

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• Daidzein waxa ay fulisaa firfircoonida ka hortagga burooyinka unugyada kansarka kaadiheysta iyada oo la joojinayo dariiqa FGFR3.
• Shikimic acid wuxuu kor u qaadaa soo-dhoweynta estrogen (ER) - unugyada kansarka naasaha ee togan ee kororka iyada oo loo marayo kicinta calaamadaha NF-kB.
• Soosaarida qorfaha aqueous (ACE-c) ee ka soo baxa jilif Cinnamomum cassia waxay sababtaa apoptosis ee khadka unugyada kansarka ilmagaleenka ee bini'aadamka (SiHa) iyada oo luminaysa awoodda xuubka mitochondrial.
• Saamaynta ka-hortagga ee butyric acid, nicotinamide, calcium glucarate oo keliya ama isku-darka inta lagu jiro 7, 12-dimethylbenz (a) anthracene waxay keentay burogenesis maqaarka jiirka iyada oo loo marayo qaabaynta K-Ras-PI3K-AKTpathway iyo micro RNA-yada la xidhiidha.
• Horumarka cilmi baarista ee saameynta ka hortagga kansarka ee fitamiin K2.
• https://my.clevelandclinic.org/health/diseases/24266-extramammary-pagets-disease
• https://www.ncbi.nlm.nih.gov/books/NBK493224