Cuntooyinka loogu talagalay Kansarka Isku-dhafka ah ee Ductal iyo Lobular!

Hordhac

Cuntooyinka loogu talagalay Kansarka Isku-dhafan ee Ductal iyo Lobular waa in loo gaaryeelaa qof kasta waana in uu la qabsado marka daawaynta kansarka ama hidde-sidaha buradu ay isbeddelaan. Shakhsiyaynta iyo la qabsiga waa in ay tixgeliyaan dhammaan maaddooyinka firfircoon ama bioactives ee ku jira cuntooyinka kala duwan marka loo eego bayooloojiyada unugyada kansarka, genetics, daawaynta, xaaladaha qaab nololeedka iyo doorbidka cuntada. Sidaa darteed iyada oo nafaqadu ay tahay mid ka mid ah go'aamada aadka muhiimka u ah bukaanka kansarka iyo qofka khatarta ugu jira kansarka inuu sameeyo - sida loo doorto cuntooyinka uu cuno maaha hawl fudud.

Kansarka Naasaha Isku-dhafka ah iyo Kansarka Lobular miyay muhiim u tahay waxa khudaarta, miraha, lawska, iniinaha qofku cuno?

Su'aasha nafaqeynta aadka u badan ee ay weydiiyaan bukaannada kansarka iyo shakhsiyaadka halista ugu jira hidde-sidaha kansarka waa - kansarka sida Naasaha Isku-dhafan ee Ductal iyo Lobular Carcinoma miyay macno samaynayaan cuntooyinka aan cuno iyo kuwa aanan samayn? Mise haddii aan raaco cunto ku salaysan geedka ayaa intaas ugu filan kansarka sida Kansarka Naasaha Isku-dhafan ee Ductal iyo Lobular?

Tusaale ahaan miyay muhiim tahay haddii khudradda New Zealand Isbinaajka la isticmaalo in ka badan marka loo eego Mustard Shiinaha? Miyay wax farqi ah samaynaysaa haddii khudaarta Pummelo laga doorbido Raspberry Cas? Sidoo kale haddii xulashooyin la mid ah loo sameeyo nuts/abuurka sida Butternut oo ka sarreeya Chestnut Yurub iyo garaacyada sida Gram Bean oo ka sarreeya Yardlong Bean. Haddii waxa aan cunaa ay arrintu khusayso- haddaba sidee loo aqoonsan karaa cuntooyinka lagu taliyey in laga helo Kansarka Naasaha Isku-dhafan ee Ductal iyo Lobular oo ma isku mid baa jawaab u tahay qof kasta oo leh isla cudurka ama khatarta hidde-sidaha?

Haa! Cuntooyinka aad cuntid waxay udub dhexaad u yihiin Kansarka Naasaha Isku-dhafan ee Ductal iyo Lobular!

Talooyinka cuntadu waxay noqon karaan kuwo isku mid ah qof kasta oo way ka duwanaan karaan xitaa ogaanshaha isku midka ah iyo khatarta hidda-socodka.

Dhammaan cuntooyinka ( khudaarta, miraha, lawska, iniinaha, garaaca, saliidaha iwm.) iyo kaabayaasha nafaqadu waxay ka kooban yihiin wax ka badan hal walxo molecular ama bio-actives oo qiyaas iyo tiro kala duwan leh. Walax kasta oo firfircooni waxay leedahay hab u gaar ah oo wax qabad - kaas oo noqon kara firfircooni ama xannibaadda dariiqyada biochemical ee kala duwan. Cuntooyinka si fudud loo sheegay iyo kaabisyada lagu taliyay waa kuwa aan keenin korodhka wadayaasha molecular ee kansarka laakiin la yareeyo. Haddii kale cuntooyinkaas waa inaan lagu talin. Cuntooyinka waxaa ku jira maaddooyin badan oo firfircoon - markaa marka la qiimeynayo cuntooyinka iyo kaabayaasha waxaad u baahan tahay inaad tixgeliso saameynta dhammaan maaddooyinka firfircoon si wadajir ah halkii aad ka ahaan lahayd mid gaar ah.

Tusaale ahaan Pummelo waxa ku jira maaddooyinka firfircoon ee Quercetin, Apigenin, Beta-sitosterol, Isoliquiritigenin, Curcumin. Raspberry-ka cas waxaa ku jira maaddooyin firfircoon oo Quercetin, Ellagic Acid, Beta-sitosterol, Isoliquiritigenin, Curcumin iyo kuwa kale oo suurtagal ah.

Khalad caadi ah oo la sameeyo marka la go'aaminayo oo la dooranayo cuntooyinka la cuno ee Naasaha Isku dhafan Ductal iyo Lobular Carcinoma - waa in la qiimeeyo oo kaliya maaddooyinka firfircoon ee la doortay ee ku jira cuntooyinka oo la iska indhatiro inta kale. Sababtoo ah maaddooyinka kala duwan ee firfircoon ee ku jira cuntooyinka ayaa laga yaabaa inay saameyn iska soo horjeeda ku yeeshaan darawalada kansarka - ma qaadan kartid maaddooyinka firfircoon ee cuntooyinka iyo kaabayaasha si loo gaaro go'aanka nafaqeynta ee Naasaha Isku-dhafka Ductal iyo Lobular Carcinoma.

HAA – DOORASHOOYINKA CUNTADA EE KANSARKA WAXAY U TAAGAN YAHAY. GO'AANKA NAFAQADA waa in ay tixgeliyaan dhammaan walxaha firfircoon ee CUNTADA.

Xirfadaha Loo Baahan Yahay Nafaqaynta Shakhsiyaynta Naasaha Isku-dhafka Ductal iyo Lobular Carcinoma?

Nafaqada shakhsi ahaaneed ee kansarka sida Kansarka Naasaha Isku-dhafan iyo Kansarka Lobular wuxuu ka kooban yahay cuntooyin/kaabyo lagu taliyey; Cuntooyinka aan lagu talin/kabka tusaale ahaan cunto karinta kuwaas oo mudnaanta siiya isticmaalka cuntooyinka lagu taliyay. Tusaale nafaqeynta gaarka ah ayaa tan lagu arki karaa link.

Go'aaminta cuntooyinka lagu taliyey iyo in kale waa mid aad u dhib badan, waxay u baahan tahay khibrada Naasaha Isku-dhafan ee Ductal And Lobular Carcinoma biology, sayniska cuntada, genetics, biochemistry oo ay weheliso faham wanaagsan oo ku saabsan sida daawaynta kansarka u shaqeyso iyo baylahda la xidhiidha taas oo daawadu ay joojin karto waxtarka.

Khibradda UGU YAR EE AQOONTA EE LOO BAAHAN YAHAY NAFAQADA SHAQSIYADEEDKA KANSARKA WAA: NOLOLIGA KANSARKA, CUNTADA CUNTADA, DAAWAYNTA KANSARKA IYO HIDDAHA HIDDAHA.

Astaamaha kansarrada sida Naasaha Isku-dhafan Ductal iyo Lobular Carcinoma

Dhammaan kansarrada sida Kansarka Isku-dhafan ee Naasaha iyo Kansarka Lobular waxa lagu gartaa hab gaar ah oo dariiqooyin kiimikaad ah - dariiqooyinka saxeexa ee Kansarka Isku-dhafan ee Naaska iyo Lobular. Dariiqooyin kiimikaad sida RAS-RAF Signaling, mRNA Splicing, Signaling MAPK, PI3K-AKT-MTOR Signaling waa qayb ka mid ah qeexida saxeexa ee Kansarka Isku-dhafan ee Naaska iyo Lobular. Hidde-sideyaasha kansarku qof walba wuu ka duwanaan karaa sidaas darteed saxiixooda gaarka ah ee kansarku wuxuu noqon karaa mid gaar ah.

Daawaynta waxtarka u leh Kansarka Isku-dhafan ee Naasaha iyo Kansarka Lobular waxay u baahan yihiin inay ogaadaan dariiqooyinka biochemical ee la xidhiidha saxeexa bukaanka kansarka iyo shakhsiga khatarta hidde-sidaha. Sidaa darteed daawayn kala duwan oo leh habab kala duwan oo ficil ah ayaa waxtar u leh bukaanada kala duwan. Si la mid ah iyo sababo la mid ah cuntooyinka iyo kaabista waxay u baahan yihiin in shaqsi kasta loo gaaryeelo. Sidaa awgeed cuntooyinka iyo kaabista qaar ayaa lagula taliyaa Kansarka Naasaha Isku-dhafan ee Ductal iyo Lobular marka la qaadanayo daawaynta kansarka Shucaaca, iyo cuntooyinka qaar iyo kaabista laguma talinayo.

Ilaha sida cBioPortal iyo qaar kale oo badan ayaa bixiya xogta bukaan-socodka ee aan la magacaabin ee laga helay tijaabooyinka bukaan-socodka ee dhammaan calaamadaha kansarka. Xogtan waxay ka kooban tahay tafaasiisha daraasadda tijaabada caafimaad sida cabbirka saamiga / tirada bukaannada, kooxaha da'da, jinsiga, qowmiyadda, daawaynta, goobta burooyinka iyo isbeddellada hidde-sidaha.

MAP3K1, AKAP9, NF1, AKT1 iyo LAMA2 waa hiddo-wadaha ugu sarreeya ee la soo sheegay ee Kansarka Naaska Isku-dhafan ee Ductal iyo Lobular. MAP3K1 ayaa lagu soo warramey 8.6 % bukaannada matala dhammaan tijaabooyinka caafimaad. Waxaana AKAP9 lagu sheegay 3.5 %. Isku darka xogta bukaan-socodka ee dadweynaha ayaa daboolaya da'da 34 ilaa 87. 0.4 % xogta bukaanka waxaa loo aqoonsaday inay yihiin rag. Naasaha Isku-dhafan ee Ductal iyo Lobular Carcinoma biology oo ay weheliso hidde-sideyaasha la soo sheegay ayaa si wada jir ah u qeexaya dariiqooyinka biochemical ee saxeexa ee dadweynaha ee kansarkan. Haddii genetics-ka burada kansarka shakhsi ahaaneed ama hiddo-wadaha ka qaybqaata khatarta sidoo kale waa la yaqaan markaa waa in sidoo kale loo isticmaalo shakhsiyaynta nafaqada.

Dookhyada nafaqeynta waa in ay iswaafaqaan shaqsi walba saxiixiisa.

Cuntada iyo Kaabayaasha Naasaha Isku-dhafan ee Ductal iyo Lobular Carcinoma

Bukaanka Kansarka

Bukaanjiifka kansarka ee ku jira daawaynta ama daryeelka palliative waxay u baahan yihiin inay go'aan ka gaadhaan cuntada iyo kaabista - kaloriinta cuntada ee loo baahan yahay, maaraynta waxyeellooyin kasta oo daawaynta iyo sidoo kale hagaajinta maaraynta kansarka. Dhammaan cuntooyinka dhirta ku salaysan maaha kuwo siman oo doorashada iyo kala horraysiinta cuntooyinka kuwaas oo shakhsi ahaan loo habeeyey oo loo habeeyey daawaynta kansarka ee socota waa muhiim oo dhib badan. Waa kuwan tusaalayaal siinaya tilmaamo lagu samaynayo go'aannada nafaqada.

Dooro khudradda cusub ee ZEALAND isbinaajka ama sharoobada shiinaha?

Khudaarta New Zealand Spinach waxay ka kooban tahay waxyaabo badan oo firfircoon ama bioactives sida Quercetin, Myricetin, Apigenin, Beta-sitosterol, Isoliquiritigenin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida NFKB Signaling, Glucocorticoid Signaling, JAK-STAT Signaling iyo PI3K-AKT-MTOR Signaling iyo kuwa kale. Isbinaajka New Zealand waxa lagula talinayaa Kansarka Naasaha Isku-dhafan ee Ductal iyo Lobular marka daawaynta kansarka ee socota ay tahay Shucaac. Tani waa sababta oo ah Spinach New Zealand waxay wax ka beddeshaa dariiqyada biochemical ee si cilmiyeysan loo soo sheegay si loo dareemo saameynta shucaaca.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee khudaarta Chinese Mustard waa Quercetin, Myricetin, Apigenin, Beta-sitosterol, Isoliquiritigenin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida Cadaadiska Oxidative, Dib-u-habaynta Matrix-ka-ka-baxsan iyo Calaamadaynta TGFB iyo kuwa kale. Mustard Shiineys ah laguma talinayo Kansarka Naasaha Isku-dhafan iyo Kansarka Lobular marka daaweynta kansarka ee socota ay tahay Shucaac sababtoo ah waxay wax ka beddeshaa dariiqyada biochemical ee ka dhigaya daaweynta kansarku mid adkaysi u leh ama ka jawaabi kara.

Qudaarta cusub ee ZEALAND isbinaajka ayaa lagula talinayaa in la dul maro khardal shiinaha oo loogu talagalay Kansarka Ductal iyo Lobular ee Naasaha Isku-dhafka ah iyo Shucaaca daawaynta.

Dooro midhaha cas raspberry ama PUMMELO?

Khudradu waxay ka kooban tahay waxyaabo badan oo firfircoon ama bioactives sida Quercetin, Ellagic Acid, Beta-sitosterol, Isoliquiritigenin, Curcumin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida Dib-u-habaynta Matrixka Extracellular Matrix Remodelling, Glucocorticoid Signaling, Cycle Cell iyo Epithelial to Mesenchymal Transition iyo kuwa kale. Raspberry cas ayaa lagula talinayaa Kansarka Naasaha Isku-dhafan ee Ductal iyo Lobular marka daawaynta kansarka ee socota ay tahay Shucaac. Tani waa sababta oo ah Raspberry Cas ayaa wax ka beddelaya dariiqyada biochemical ee si cilmiyeysan loo soo sheegay si loo dareemo saameynta shucaaca.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee ku jira miro Pummelo waa Quercetin, Apigenin, Beta-sitosterol, Isoliquiritigenin, Curcumin. Maaddooyinkan firfircooni waxay wax ka qabtaan dariiqooyin kiimikaad oo kala duwan sida Cadaadiska Oxidative, Dayactirka DNA iyo Ka jawaab celinta Cadaadiska Kulaylka iyo kuwa kale. Pummelo laguma talinayo Kansarka Naasaha Isku-dhafka ah iyo Lobular marka daawaynta kansarka ee socota ay tahay Shucaac sababtoo ah waxay wax ka beddeshaa dariiqyada biochemical ee ka dhigaya daaweynta kansarku mid adkaysi u leh ama ka jawaabi kara.

Raspberry cas ee miraha waxaa lagula talinayaa PUMMELO oo loogu talagalay Kansarka Ductal iyo Lobular isku dhafan ee naaska iyo shucaaca daawaynta.

Dooro basbaaska lowska ama XABADAHA YURUB?

Butternut wuxuu ka kooban yahay waxyaabo badan oo firfircoon ama bioactives sida Myricetin, Apigenin, Beta-sitosterol, Isoliquiritigenin, Curcumin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida NFKB Signaling, Glucocorticoid Signaling, JAK-STAT Signaling iyo PI3K-AKT-MTOR Signaling iyo kuwa kale. Butternut ayaa lagula talinayaa Kansarka Naasaha Isku-dhafan ee Ductal iyo Lobular marka daawaynta kansarka ee socota ay tahay Shucaac. Tani waa sababta oo ah Butternut waxay wax ka beddeshaa dariiqyada biochemical ee si cilmiyeysan loo soo sheegay si loo dareemo saameynta shucaaca.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee ku jira Chestnut Yurub waa Quercetin, Ellagic Acid, Myricetin, Apigenin, Beta-sitosterol. Maaddooyinkan firfircooni waxay wax ka qabtaan dariiqooyin kiimikaad oo kala duwan sida Cadaadiska Oxidative iyo kuwa kale. Chestnut Yurub laguma talinayo Kansarka Naasaha Isku-dhafan iyo Lobular Carcinoma marka daawaynta kansarka ee socota ay tahay Shucaac sababtoo ah waxay wax ka beddeshaa dariiqyada biochemical ee ka dhigaya daawaynta kansarku mid adkaysi u leh ama aan ka jawaabin.

BUTTERNUT ayaa lagula talinayaa laabta YURUB ee loogu talagalay Kansarka Isku-dhafka ah ee Ductal iyo Lobular iyo Shucaaca daawaynta.

Shakhsiyaadka leh Khatarta Hidde ee Kansarka

Su'aasha ay weydiiyaan shakhsiyaadka leh khatarta hidde-sidaha ee Naasaha Isku-dhafka Ductal iyo Lobular Carcinoma ama taariikhda qoysku waa "Maxaan Cunnaa Si Ka Duwan Kii Hore?" iyo sida ay tahay inay doortaan cuntooyinka iyo kaabista si loo maareeyo khatarta cudurka. Maadaama khatarta kansarku aanay jirin wax la qaban karo marka la eego daawaynta - go'aannada cuntooyinka iyo kaabista ayaa noqda mid muhiim ah iyo mid ka mid ah wax yaabaha yar ee la qaban karo ee la samayn karo. Dhammaan cuntooyinka dhirta ku salaysan maaha kuwo siman oo ku salaysan hidde-sideyaasha la aqoonsaday iyo saxiixa dariiqa - doorashooyinka cuntada iyo kaabista waa in la shakhsiyeeyo.

Dooro khudaar GIANT BUTTERBUR ama GARDEN RHUBARB?

Khudaarta Giant Butterbur waxay ka kooban tahay waxyaabo badan oo firfircoon ama bioactives sida Apigenin, Curcumin, Lupeol, Lycopene, Delphinidin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida WNT Beta Catenin Signaling, Apoptosis, PI3K-AKT-MTOR Signaling iyo P53 Signaling iyo kuwa kale. Giant Butterbur waxaa lagula talinayaa halista Naasaha Isku-dhafan ee Ductal iyo Lobular Carcinoma marka khatarta hidde-sidaha la xiriirta ay tahay AKAP9. Tani waa sababta oo ah Giant Butterbur waxay kordhisaa dariiqyada biochemical ee ka soo horjeeda wadayaasha saxeexa.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee ku jira Beerta Rhubarb ee khudradda waa Apigenin, Curcumin, Quercetin, Emodin, Rhein. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida WNT Beta Catenin Signaling, Dib-u-habaynta Matrix-ka-baxa ah iyo PI3K-AKT-MTOR Signaling iyo kuwa kale. Beerta Rhubarb laguma talinayo marka halista Naasaha Isku-dhafan Ductal iyo Lobular Carcinoma marka khatarta hidde-sidaha lala xiriiriyo ay tahay AKAP9 sababtoo ah waxay kordhisaa dariiqyada saxiixa.

BUTTERBUR WAYN OO KHUDUREED AYAA LAGU TALAGALINAYAA RHUBARBKA BEERTA KHAP9 KHATARTA HIDDAHA EE KANSARKA.

Dooro Miraha NANCE ama SQUASHBERRY?

Miraha Nance waxaa ku jira waxyaabo badan oo firfircoon ama bioactives sida Apigenin, Curcumin, Lupeol, Delphinidin, Formononetin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida PI3K-AKT-MTOR Signaling, Hypoxia iyo P53 Signaling iyo kuwa kale. Nance waxa lagula taliyaa halista naasaha isku-dhafan ee dhuunta-mareenka ah iyo Kansarka Lobular marka khatarta hidde-sidaha la xidhiidha ay tahay AKAP9. Tani waa sababta oo ah Nance waxay kordhisaa dariiqyada biochemical ee ka soo horjeeda darawaliinta saxeexa.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee miraha Squashberry waa Apigenin, Curcumin, Lupeol, Lycopene, Delphinidin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida WNT Beta Catenin Signaling, Isbaarada Wareegga Gacanta iyo PI3K-AKT-MTOR Signaling iyo kuwa kale. Squashberry laguma talinayo marka halista Naasaha Isku-dhafan Ductal iyo Lobular Carcinoma marka khatarta hidde-sidaha lala xiriiriyo ay tahay AKAP9 sababtoo ah waxay kordhisaa dariiqooyinka saxiixa.

FRUIT NANCE waxa lagula taliyaa SQUASHBERRY si loo helo halista hidda-sidaha AKAP9 ee kansarka.

Dooro Nut COMMON WALNUT ama FLAXSEED?

Walnut-ka caadiga ah waxa ku jira maaddooyin badan oo firfircoon ama bioactives sida Curcumin, Quercetin, Ellagic Acid, Lupeol, Delphinidin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida Apoptosis, PI3K-AKT-MTOR Signaling, Signaling Factor Growth iyo P53 Signaling iyo kuwa kale. Walnut-ka caadiga ah waxa lagula taliyaa khatarta Naasaha Isku-dhafan ee Ductal iyo Lobular Carcinoma marka khatarta hidde-sidaha la xidhiidha ay tahay AKAP9. Tani waa sababta oo ah Walnut-ka caadiga ah wuxuu kordhiyaa dariiqooyinka biochemical ee ka hor imaanaya saxiixyada wadayaasha.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee Flaxseed waa Apigenin, Curcumin, Lupeol, Delphinidin, Formononetin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida WNT Beta Catenin Signaling, PI3K-AKT-MTOR Signaling iyo MAPK Signaling iyo kuwa kale. Flaxseed laguma talinayo marka halista Naasaha Isku-dhafan Ductal iyo Lobular Carcinoma marka khatarta hidde-sidaha lala xiriiriyo ay tahay AKAP9 sababtoo ah waxay kordhisaa dariiqyada saxiixa.

Walnut Caanka ah ayaa lagula talinayaa FLAXSeed si loogu helo Khatarta Hiddada ee AKAP9.

In Gabagabo

Cuntooyinka iyo Kaabayaasha la doortay ayaa ah go'aamo muhiim u ah kansarrada sida Naasaha Isku-dhafan ee Ductal iyo Lobular Carcinoma. Bukaannada Kansarka Isku-dhafan ee Ductal iyo Lobular ee Kansarka iyo shakhsiyaadka leh khatarta hidde-sidaha waxay had iyo jeer qabaan su'aashan: "Waa maxay cuntooyinka iyo kaabisyada nafaqeynta ee lagu taliyay aniga iyo kuwa aan ahayn?" Waxaa jira aaminsanaan guud oo ah fikrad khaldan oo ah in dhammaan cuntooyinka dhirta ku salaysan ay faa'iido yeelan karaan ama aysan ahayn laakiin aan waxyeello lahayn. Cuntooyinka qaarkood iyo kaabisyada qaarkood waxay faragelin karaan daawaynta kansarka ama waxay kor u qaadi karaan wadayaasha dariiqyada molecular ee kansarka.

Waxaa jira noocyo kala duwan oo calaamado kansar ah sida Kansarka Naasaha Isku-dhafka ah iyo Lobular Carcinoma, mid kasta oo leh hidde-sidaha burooyinka oo kala duwan oo leh kala duwanaansho genomic oo dheeraad ah oo qof kasta ah. Intaa waxaa dheer daawaynta kansar kasta iyo kiimoterabi kasta waxay leeyihiin hab wax-qabad oo gaar ah. Cunto kasta sida Isbinaajka New Zealand waxay ka kooban tahay noocyo kala duwan oo bioactives ah oo tirooyin kala duwan leh, kuwaas oo saameyn ku leh noocyo kala duwan oo kala duwan oo ah dariiqyada biochemical. Qeexida nafaqeynta shakhsi ahaaneed waa talooyinka cuntada ee gaarka ah ee tilmaamaya kansarka, daawaynta, genetics, qaab nololeedka iyo arrimo kale. Go'aannada shakhsiyaynta nafaqada ee kansarka waxay u baahan yihiin aqoonta bayoolajiga kansarka, sayniska cuntada iyo fahamka daaweynta kemotherabi ee kala duwan. Ugu dambeyntii marka ay jiraan isbeddel daaweyn ama genomics cusub ayaa la aqoonsaday - shakhsiyeynta nafaqeynta waxay u baahan tahay dib-u-qiimeyn.

Xalka shakhsiyaynta nafaqaynta ee addon ayaa ka dhigaysa go'aan qaadashada mid fudud oo meesha ka saaraysa dhammaan malo-awaalka ka jawaabaya su'aasha, "Cunto noocee ah ayaan dooran karaa ama ma dooran karaa Kansarka Naaska Isku-dhafan ee Ductal iyo Lobular?". Kooxda edbinta badan ee addon waxaa ka mid ah dhakhaatiirta kansarka, saynisyahano caafimaad, injineerada software iyo saynisyahano xogta.

tixraacyada

• Brca Mapk Hp Msk 2021
• Tilmaamaha isbeddelka somatic ee 2,433 kansar naasaha ayaa nadiifiya muuqaalkooda genomic iyo transcriptomic.
• Dhaqdhaqaaqa soo noqoshada kansarka naasaha ayaa muujinaya soo noqnoqoshada soo daaha ee ER-koox-hoosaadka genomic.
• Qaab dhismeedka genomic iyo transcriptomic ee 2,000 burooyinka naaska ayaa muujinaya kooxo hoose oo cusub.
• Dib-u-hagaajinta DNA-da iyo waxqabadyada dib-u-celinta iyo horjoogayaasha apurinic / apyrimidinic endonuclease 1 / redox factor factor 1 (APE1 / Ref-1): falanqayn isbarbardhigga iyo baaxaddooda iyo xaddidaaddooda horumarinta daroogada kansarka.
• Faytamiin C wuxuu xoojiyaa isbeddellada epigenetic ee ay keentay 5-azacytidine iyo xiritaanka wareegga unugyada ee khadadka unugyada kansarka hepatocellular HLE iyo Huh7.
• Liinta flavonoid naringenin waxay kicisaa hagaajinta DNA ee unugyada kansarka qanjirka 'prostate'.
• Curcumin waxay joojisaa koritaanka iyada oo loo marayo marinka Wnt/β-catenin ee unugyada kansarka sanbabada ee aan unugyada yaryar.
• Ka-hortagga ka-hortagga saamaynta xayeysiinta ee shaaha cad iyo kafeyn ee PhIP-ku-abuuray tumorigenesis iyo muujinta beta-catenin ee jiirka.