Cuntooyinka loogu talagalay Kansarka unugga Squamous Kaadi-haysta!

Hordhac

Cuntooyinka loogu talagalay Kansarka unugga Squamous-ka ee kaadi-haysta waa in loo gaaryeelaa qof walba waana in uu la qabsado marka daawaynta kansarka ama hidde-sidaha buradu ay isbeddelaan. Shakhsiyaynta iyo la qabsiga waa in ay tixgelisaa dhammaan maaddooyinka firfircoon ama bioactives ee ku jira cuntooyinka kala duwan marka loo eego bayooloojiyada unugyada kansarka, genetics, daawaynta, xaaladaha qaab nololeedka iyo doorbidka cuntada. Sidaa darteed iyadoo nafaqadu ay tahay mid ka mid ah go'aamada aadka muhiimka u ah bukaanka kansarka iyo qofka halista ugu jira kansarka inuu sameeyo - sida loo doorto cuntooyinka uu cuno maaha hawl fudud.

Kansarka unugyada squamous-ka ee kaadi-haysta kaadida waa nooc gaar ah oo kansarka kaadiheysta ah oo lagu garto pathology-ga iyo dabeecadeeda caafimaad. Waxay soo bandhigaysaa caqabado gaar ah oo ku saabsan ogaanshaha iyo daawaynta, sida ka muuqata shucaaca iyo tafatiran ee tilmaamayaasha cudurka kansarka unugyada squamous cell pathology. Dajinta kansarkan ayaa muhiim u ah go'aaminta daawaynta habboon, taas oo inta badan ku lug leh isku-darka kemotherabi, daawaynta shucaaca, iyo qalliin. Heerka badbaadada kansarka kaadiheysta unugyada squamous cell carcinoma waxay si weyn ugu xiran tahay heerka cudurka iyo waxtarka istiraatiijiyadda daaweynta ee la doortay. Tilmaamaha daawaynta kansarka qanjidhada kaadiheysta waxay xooga saarayaan muhiimada ay leedahay wax ka qabashada arrimaha bukaanka shaqsiga ah, oo ay ku jiraan joogitaanka arrimaha halista sida dhagxaan kaadiheysta, kaadiheysta kaadiheysta, iyo caabuqyada sida schistosomiasis. Kiisaska hore u maray, sida kaadiheysta metastatic squamous cell carcinoma, waxay u baahan yihiin habab daaweyn oo gardarro ah. Daraasaduhu waxay sahamiyeen doorka biomarkers sida GATA3 ee saadaasha iyo daaweynta cudurkan. Fahamka calaamadaha kaadiheysta unugyada squamous cell squamous cell ayaa muhiim u ah ogaanshaha waqtiga iyo faragelinta, hagaajinta saadaasha guud ee bukaanada.

Kansarka unugyada squamous-ka ee kaadi-haysta dhib miyay u leedahay waxa khudaarta, miraha, lawska, iniinaha qofku cuno?

Su'aasha nafaqeynta aadka u badan ee ay weydiiyaan bukaannada kansarka iyo shakhsiyaadka halista ugu jira hidde-sidaha kansarka waa - kansarka sida Kansarka Squamous Cell squamous Cell muhiim ma u yahay cuntooyinka aan cuno iyo kuwa aanan samayn? Mise haddii aan raaco cunto ku salaysan geedka intaas miyay ku filan tahay kansarka sida kaadiheysta Squamous Cell Carcinoma?

Tusaale ahaan miyay muhiim tahay haddii Salad Rocket Salad la isticmaalo in ka badan marka loo eego Squash Winter? Miyay wax farqi ah samaynaysaa haddii midhaha Canabka laga door bido Bayberry? Sidoo kale haddii xulashooyin la mid ah loo sameeyo nuts/abuurka sida Almond oo ka sarreeya Pistachio iyo garaacyada sida Broad Bean oo ka sarreeya Mung Bean. Oo haddii waxa aan cunaa ay arrintu khusayso - haddaba sidee loo aqoonsan karaa cuntooyinka lagu taliyay kansarka kaadiheysta Squamous Cell oo ma isku mid baa jawaab u tahay qof kasta oo leh isla cudurka ama halista hidde-sidaha?

Haa! Cuntooyinka aad cuntid waxay udub dhexaad u yihiin kansarka kaadiheysta squamous cell!

Talooyinka cuntadu waxay noqon karaan kuwo isku mid ah qof kasta oo way ka duwanaan karaan xitaa ogaanshaha isku midka ah iyo khatarta hidda-socodka.

Dhammaan cuntooyinka ( khudaarta, miraha, lawska, iniinaha, garaaca, saliidaha iwm.) iyo kaabayaasha nafaqadu waxay ka kooban yihiin wax ka badan hal walxo molecular ama bio-actives oo qiyaas iyo tiro kala duwan leh. Walax kasta oo firfircooni waxay leedahay hab u gaar ah oo wax qabad - kaas oo noqon kara firfircooni ama xannibaadda dariiqyada biochemical ee kala duwan. Cuntooyinka si fudud loo sheegay iyo kaabisyada lagu taliyay waa kuwa aan keenin korodhka wadayaasha molecular ee kansarka laakiin la yareeyo. Haddii kale cuntooyinkaas waa inaan lagu talin. Cuntooyinka waxaa ku jira maaddooyin badan oo firfircoon - markaa marka la qiimeynayo cuntooyinka iyo kaabayaasha waxaad u baahan tahay inaad tixgeliso saameynta dhammaan maaddooyinka firfircoon si wadajir ah halkii aad ka ahaan lahayd mid gaar ah.

Tusaale ahaan canabka waxaa ku jira maaddooyinka firfircoon ee Luteolin, Lupeol, Eugenol, Phloretin, Linolenic Acid. Bayberry waxay ka kooban tahay maaddooyinka firfircoon ee Myricetin, Luteolin, Lupeol, Eugenol, Phloretin iyo kuwo kale oo suurtagal ah.

Khalad caadi ah oo la sameeyo marka la go'aaminayo oo la dooranayo cuntooyinka loo cuno Kaadi-haysta Kaarka Squamous Cell - waa in la qiimeeyo oo kaliya maaddooyinka firfircoon ee la doortay ee ku jira cuntooyinka oo la iska indhatiro inta kale. Sababtoo ah maaddooyinka kala duwan ee firfircoon ee ku jira cuntooyinka ayaa laga yaabaa inay saameyn iska soo horjeeda ku yeeshaan darawalada kansarka - ma qaadan kartid maaddooyinka firfircoon ee cuntooyinka iyo kaabayaasha si aad u go'aansato nafaqeynta kaadiheysta Squamous Cell Carcinoma.

HAA – DOORASHOOYINKA CUNTADA EE KANSARKA WAXAY U TAAGAN YAHAY. GO'AANKA NAFAQADA waa in ay tixgeliyaan dhammaan walxaha firfircoon ee CUNTADA.

Xirfadaha Looga Baahan Yahay Nafaqaynta Shakhsiyaynta ee Kansarka Unugyada Squamous

Nafaqada shakhsi ahaaneed ee kansarrada sida kansarka kaadiheysta Squamous Cell Carcinoma wuxuu ka kooban yahay cuntooyin / kaabis lagu taliyey; Cuntooyinka aan lagu talin/kabka tusaale ahaan cunto karinta kuwaas oo mudnaanta siiya isticmaalka cuntooyinka lagu taliyay. Tusaale nafaqeynta gaarka ah ayaa tan lagu arki karaa link.

Go'aaminta cuntooyinka lagu taliyay iyo in kale waa mid aad u adag, waxay u baahan tahay khibrad ku saabsan bayoolajiga kaadiheysta Squamous Cell Carcinoma, sayniska cuntada, genetics, biochemistry oo ay weheliso faham wanaagsan oo ku saabsan sida daawaynta kansarku u shaqeyso iyo baylahda la xidhiidha kuwaas oo daaweyntu ay ku joojin karto waxtarka.

Khibradda UGU YAR EE AQOONTA EE LOO BAAHAN YAHAY NAFAQADA SHAQSIYADEEDKA KANSARKA WAA: NOLOLIGA KANSARKA, CUNTADA CUNTADA, DAAWAYNTA KANSARKA IYO HIDDAHA HIDDAHA.

Astaamaha kansarrada sida kansarka kaadiheysta Squamous Cell Carcinoma

Dhammaan kansarrada sida Kansarka unugga Squamous-ka ee kaadi-haysta waxaa lagu sifeyn karaa waddooyin gaar ah oo kiimikaad ah - dariiqooyinka saxiixa ee Kansarka unugyada Squamous-ka ee kaadiheysta. Dariiqooyin kiimikaad sida dheef-shiid kiimikaad, Isbaarada wareegga unugyada, Calaamadaynta PI3K-AKT-MTOR, Calaamadaynta MAPK waa qayb ka mid ah qeexida saxeexa ee Kansarka unugga Squamous-ka ee kaadi haysta. Hidde-sideyaasha kansarku qof walba wuu ka duwanaan karaa sidaas darteed saxiixooda gaarka ah ee kansarku wuxuu noqon karaa mid gaar ah.

Daawaynta waxtarka u leh kansarka kaadiheysta Squamous Cell waxay u baahan yihiin inay ogaadaan dariiqyada biochemical ee la xidhiidha saxeexa bukaan kasta oo kansar ah iyo shakhsiga khatarta hidde-sidaha. Sidaa darteed daawayn kala duwan oo leh habab kala duwan oo ficil ah ayaa waxtar u leh bukaanada kala duwan. Si la mid ah iyo sababo la mid ah cuntooyinka iyo kaabista waxay u baahan yihiin in shaqsi kasta loo gaaryeelo. Sidaa awgeed cuntooyinka iyo kaabista qaar ayaa lagula taliyaa Kansarka unugyada Squamous-ka ee Kaadi-haysta marka la qaadanayo daawaynta kansarka Ifosfamide, iyo cuntooyinka qaarkood iyo kaabista laguma talinayo.

Ilaha sida cBioPortal iyo qaar kale oo badan ayaa bixiya xogta bukaan-socodka ee aan la magacaabin ee laga helay tijaabooyinka bukaan-socodka ee dhammaan calaamadaha kansarka. Xogtan waxay ka kooban tahay tafaasiisha daraasadda tijaabada caafimaad sida cabbirka saamiga / tirada bukaannada, kooxaha da'da, jinsiga, qowmiyadda, daawaynta, goobta burooyinka iyo isbeddellada hidde-sidaha.

TP53, KDM6A, ARID1A, KMT2C iyo FGFR3 waa hiddo-wadaha ugu sarreeya ee la soo sheegay ee kansarka kaadiheysta squamous. TP53 ayaa lagu soo warramey 38.5 % bukaanada matala dhammaan tijaabooyinka caafimaad. KDM6A waxaa lagu soo warramey 34.6 %. Isku darka xogta bukaan-socodka ee dadweynaha ayaa daboolaya da'da 34 ilaa 84. 63.0 % xogta bukaanka waxaa loo aqoonsaday inay yihiin rag. Biology-ga Kansarka Squamous-ka ee Kaadi-haysta oo ay weheliso hidde-sideyaasha la soo sheegay ayaa si wada jir ah u qeexaya dariiqooyinka biochemical ee saxeexa dadweynaha ee kansarkan. Haddii genetics-ka burada kansarka shakhsi ahaaneed ama hiddo-wadaha ka qaybqaata khatarta sidoo kale waa la yaqaan markaa waa in sidoo kale loo isticmaalo shakhsiyaynta nafaqada.

Dookhyada nafaqeynta waa in ay iswaafaqaan shaqsi walba saxiixiisa.

Cuntada iyo Kaabayaasha loogu talagalay Kansarka Unugyada Squamous

Bukaanka Kansarka

Bukaanjiifka kansarka ee ku jira daawaynta ama daryeelka palliative waxay u baahan yihiin inay go'aan ka gaadhaan cuntada iyo kaabista - kaloriinta cuntada ee loo baahan yahay, maaraynta waxyeellooyin kasta oo daawaynta iyo sidoo kale hagaajinta maaraynta kansarka. Dhammaan cuntooyinka dhirta ku salaysan maaha kuwo siman oo doorashada iyo kala horraysiinta cuntooyinka kuwaas oo shakhsi ahaan loo habeeyey oo loo habeeyey daawaynta kansarka ee socota waa muhiim oo dhib badan. Waa kuwan tusaalayaal siinaya tilmaamo lagu samaynayo go'aannada nafaqada.

Dooro saladhka gantaalka qudaarta ama jiilaalka?

Salad Rocket Salad waxaa ku jira waxyaabo badan oo firfircoon ama bioactives sida Quercetin, Myricetin, Luteolin, Lupeol, Eugenol. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida Dib-u-habaynta Matrix-ka Extracellular Matrix, Isbaarada Wareegga Unugyada iyo kuwa kale. Salad gantaal ah ayaa lagula talinayaa kansarka kaadiheysta Squamous cell marka daawaynta kansarka ee socota ay tahay Ifosfamide. Tani waa sababta oo ah Salad Rocket wuxuu wax ka beddelaa dariiqyada biochemical ee si cilmiyeysan loo soo sheegay si loo dareemo saameynta Ifosfamide.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee khudaarta jiilaalka Squash waa Myricetin, Luteolin, Lupeol, Eugenol, Phloretin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida Cadaadiska Oxidative iyo Signaling Hippo iyo kuwa kale. Squash jiilaalka laguma talinayo kansarka kaadiheysta squamous cell marka daawaynta kansarka ee socota ay tahay Ifosfamide sababtoo ah waxay wax ka beddeshaa dariiqyada biochemical ee ka dhigaya daaweynta kansarku mid adkaysi u leh ama aan ka jawaabin.

SALAAD KARTA SALAAD AYAA LAGULA TALINAYAA SQUASH JIILAALAHA OO LOOGU TALAGALAY Kansarka unugyada Squamous Cell squamous

Dooro midhaha BAYBERRY ama GRAPEFRUIT?

Khudradu waxay ka kooban tahay waxyaabo badan oo firfircoon ama bioactives sida Myricetin, Luteolin, Lupeol, Eugenol, Phloretin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida Faytamiin Metabolism, Wareegga Unugyada, Calaamadaynta JAK-STAT iyo Epithelial ilaa Mesenchymal Transition iyo kuwa kale. Bayberry waxaa lagula taliyaa Kansarka unugga Squamous-ka ee kaadiheysta marka daawaynta kansarka ee socota ay tahay Ifosfamide. Tani waa sababta oo ah Bayberry waxay wax ka beddeshaa dariiqyada biochemical ee si cilmiyeysan loo soo sheegay si loo dareemo saameynta Ifosfamide.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee ku jira canabka miraha waa Luteolin, Lupeol, Eugenol, Phloretin, Linolenic Acid. Maaddooyinkan firfircooni waxay wax ka qabtaan dariiqooyin kiimikaad oo kala duwan sida Cadaadiska Oxidative iyo Dayactirka DNA iyo kuwa kale. Grapefruit laguma talinayo Kansarka unugyada Squamous-ka ee kaadiheysta marka daawaynta kansarka ee socota ay tahay Ifosfamide sababtoo ah waxay wax ka beddeshaa dariiqyada biochemical ee ka dhigaya daaweynta kansarku mid adkaysi u leh ama ka jawaabi kara.

BAYBERRY MIDHAHA AYAA LAGULA TALAGAY INAY BAYBBARYDA EE KAADIHEYSA KAARSOONAMAHA Squamous cell iyo daawaynta Ifosfamide.

Dooro Nut ALMOND ama PISTACHIO?

Almond wuxuu ka kooban yahay waxyaabo badan oo firfircoon ama bioactives sida Lupeol, Eugenol, Phloretin, Linolenic Acid, Beta-sitosterol. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida JAK-STAT Signaling, Cell Cycle, Epithelial to Mesenchymal Transition iyo Isbaarada Wareegga Unugyada iyo kuwa kale. Almond waxaa lagula talinayaa kansarka kaadiheysta Squamous cell marka daawaynta kansarka ee socota ay tahay Ifosfamide. Tani waa sababta oo ah Almond waxay wax ka beddeshaa dariiqyada biochemical ee si cilmiyeysan loo soo sheegay si loo dareemo saameynta Ifosfamide.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee Pistachio waa Quercetin, Lupeol, Eugenol, Phloretin, Linolenic Acid. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida Cadaadiska Oxidative iyo Signaling Hippo iyo kuwa kale. Pistachio laguma talinayo kansarka kaadiheysta Squamous Cell marka daawaynta kansarka ee socota ay tahay Ifosfamide sababtoo ah waxay wax ka beddeshaa dariiqyada biochemical ee ka dhigaya daaweynta kansarku mid adkaysi u leh ama ka jawaabi kara.

Almond waxaa lagula taliyaa PISTACHIO ee Kansarka unugga kaadiheysta iyo daawaynta Ifosfamide.

Shakhsiyaadka leh Khatarta Hidde ee Kansarka

Su'aasha ay weydiiyaan shakhsiyaadka leh khatarta hidde-sidaha ee Kansarka Unugga Squamous Cell Kaadi-haysta ama taariikhda qoysku waa "Maxaan Cunnaa Si Ka duwan kii Hore?" iyo sida ay tahay inay doortaan cuntooyinka iyo kaabista si loo maareeyo khatarta cudurka. Maadaama khatarta kansarku aanay jirin wax la qaban karo marka la eego daawaynta - go'aamada cuntooyinka iyo kaabista ayaa noqda mid muhiim ah iyo mid ka mid ah waxyaallaha aadka u yar ee la qaban karo. Dhammaan cuntooyinka dhirta ku salaysan maaha kuwo siman oo ku salaysan hidde-sidaha la aqoonsaday iyo saxeexa dariiqa - doorashooyinka cuntada iyo kaabista waa in la shakhsiyeeyo.

Dooro Qudaar GIANT BUTTERBUR ama ALLIUM?

Khudaarta Giant Butterbur waxay ka kooban tahay waxyaabo badan oo firfircoon ama bioactives sida Curcumin, Apigenin, Lycopene, Lupeol, Daidzein. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida RAS-RAF Signaling, Cell Cycle, Epithelial to Mesenchymal Transition iyo P53 Signaling iyo kuwa kale. Giant Butterbur waxaa lagula taliyaa halista kansarka kaadiheysta Squamous Cell marka halista hidde ee la xiriirta ay tahay ARID1A. Tani waa sababta oo ah Giant Butterbur waxay kordhisaa dariiqyada biochemical ee ka soo horjeeda wadayaasha saxeexa.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee khudradda Allium waa Curcumin, Quercetin, Lupeol, Daidzein, Phloretin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida WNT Beta Catenin Signaling iyo PI3K-AKT-MTOR Signaling iyo kuwa kale. Allium laguma talinayo marka halista kaadiheysta Squamous Cell Carcinoma marka khatarta hidde ee la xiriirta ay tahay ARID1A sababtoo ah waxay kordhisaa dariiqooyinka saxiixa.

BUTTERBUR WAYN OO khudaar ah ayaa lagula taliyaa ALLIUMKA ARID1A Khatarta hidda-socodka ee Kansarka.

Dooro Miraha NANCE ama PUMMELO?

Miraha Nance waxaa ku jira waxyaabo badan oo firfircoon ama bioactives sida Curcumin, Apigenin, Lupeol, Daidzein, Myricetin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida RAS-RAF Signaling, Cell Cycle, Epithelial to Mesenchymal Transition iyo P53 Signaling iyo kuwa kale. Nance waxaa lagula taliyaa halista kansarka kaadiheysta squamous cell marka khatarta hidde ee la xiriirta ay tahay ARID1A. Tani waa sababta oo ah Nance waxay kordhisaa dariiqyada biochemical ee ka soo horjeeda darawaliinta saxeexa.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee ku jira miro Pummelo waa Curcumin, Apigenin, Quercetin, Lycopene, Lupeol. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida WNT Beta Catenin Signaling iyo Epithelial ilaa Mesenchymal Transition iyo kuwa kale. Pummelo laguma talinayo marka halista kaadiheysta Squamous Cell Carcinoma marka khatarta hidde ee la xiriirta ay tahay ARID1A sababtoo ah waxay kordhisaa dariiqooyinka saxiixa.

FRUIT NANCE waxaa lagula talinayaa PUMMELO oo loogu talagalay ARID1A khatarta hidda-socodka ee kansarka.

Dooro Nut COMMON HAZELNUT ama LAABKA?

Hazelnut-ka caadiga ah waxa ku jira maaddooyin badan oo firfircoon ama bioactives sida Curcumin, Quercetin, Lycopene, Lupeol, Daidzein. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida RAS-RAF Signaling, Cell Cycle, Epithelial to Mesenchymal Transition iyo P53 Signaling iyo kuwa kale. Hazelnut-ka caadiga ah ayaa lagula taliyaa halista kansarka kaadiheysta Squamous cell marka khatarta hidde-sidaha la xiriirta ay tahay ARID1A. Tani waa sababta oo ah Hazelnut Common waxay kordhisaa dariiqyada biochemical ee ka soo horjeeda wadayaasha saxeexa.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee ku jira Chestnut waa Curcumin, Apigenin, Ellagic Acid, Lycopene, Lupeol. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida WNT Beta Catenin Signaling iyo Epithelial ilaa Mesenchymal Transition iyo kuwa kale. Chestnut laguma talinayo marka halista kansarka kaadiheysta Squamous cell marka khatarta hidde-ku-xiran ay tahay ARID1A sababtoo ah waxay kordhisaa dariiqooyinka saxeexa.

HAZELNUT caam ah ayaa lagula talinayaa xabadka ARID1A khatarta hidda-socodka ee kansarka.

In Gabagabo

Cuntooyinka iyo Kaabayaasha la doortay ayaa ah go'aamo muhiim u ah kansarrada sida kansarka kaadiheysta squamous cell. Bukaannada Kansarka Unugyada Squamous-ka ee Kaadi-haysta iyo shakhsiyaadka leh khatarta hidde-sidaha waxay had iyo jeer qabaan su'aashan: "Waa maxay cuntooyinka iyo nafaqooyinka nafaqada ee lagu taliyey aniga iyo kuwa aan ahayn?" Waxaa jira aaminsanaan guud oo ah fikrad khaldan oo ah in dhammaan cuntooyinka dhirta ku salaysan ay faa'iido yeelan karaan ama aysan ahayn laakiin aan waxyeello lahayn. Cuntooyinka qaarkood iyo kaabisyada qaarkood waxay faragelin karaan daawaynta kansarka ama waxay kor u qaadi karaan wadayaasha dariiqyada molecular ee kansarka.

Waxaa jira noocyo kala duwan oo tilmaamayaasha kansarka sida Kansarka Squamous Cell Kaadi-haye, mid kasta oo leh hidde-sidaha burooyinka oo kala duwan oo leh kala duwanaansho genomic oo dheeraad ah oo qof kasta ah. Intaa waxaa dheer daawaynta kansar kasta iyo kiimoterabi kasta waxay leeyihiin hab wax-qabad oo gaar ah. Cunto kasta sida Salad Rocket waxay ka kooban tahay noocyo kala duwan oo bioactives ah oo tirooyin kala duwan leh, kuwaas oo saameyn ku leh noocyo kala duwan oo kala duwan oo ah dariiqyada biochemical. Qeexida nafaqeynta shakhsi ahaaneed waa talooyinka cuntada ee gaarka ah ee tilmaamaya kansarka, daawaynta, genetics, qaab nololeedka iyo arrimo kale. Go'aannada shakhsiyaynta nafaqada ee kansarka waxay u baahan yihiin aqoonta bayoolajiga kansarka, sayniska cuntada iyo fahamka daaweynta kemotherabi ee kala duwan. Ugu dambeyntii marka ay jiraan isbeddel daaweyn ama genomics cusub ayaa la aqoonsaday - shakhsiyeynta nafaqeynta waxay u baahan tahay dib-u-qiimeyn.

Xalka shakhsiyaynta nafaqeynta ee addon ayaa ka dhigaysa go'aan qaadashada mid fudud oo meesha ka saaraysa dhammaan malo-awaalka ka jawaabaya su'aasha, "Cunto noocee ah ayaan dooran karaa ama ma dooran karaa Kansarka Unugga Squamous Cell?". Kooxda edbinta badan ee addon waxaa ka mid ah dhakhaatiirta kansarka, saynisyahano caafimaad, injineerada software iyo saynisyahano xogta.

tixraacyada

• Saamaynta Msk 2017
• Falanqaynta Pan-kansarka ee genomes oo dhan.
• Dib-u-hagaajinta DNA-da iyo waxqabadyada dib-u-celinta iyo horjoogayaasha apurinic / apyrimidinic endonuclease 1 / redox factor factor 1 (APE1 / Ref-1): falanqayn isbarbardhigga iyo baaxaddooda iyo xaddidaaddooda horumarinta daroogada kansarka.
• Saamaynta Ka-hortagga Metastatic ee Lupeol iyada oo loo marayo Joojinta Waddada MAPK/ERK ee Kansarka Sambabada.
• β-Caryophyllene ee Saliida Muhiimka ah ee ka timid Chrysanthemum Boreal waxay keentaa G₁ Qabashada Unugyada Kansarka Sambabada ee Bani'aadamka ee Wareega Unugga Wajiga.
• Liinta flavonoid naringenin waxay kicisaa hagaajinta DNA ee unugyada kansarka qanjirka 'prostate'.
• Retinol wuxuu hoos u dhigaa heerarka borotiinka beta-catenin ee khadadka unugyada kansarka mindhicirka ee retinoic acid u adkaysta.
• Horumarka cilmi baarista ee saameynta ka hortagga kansarka ee fitamiin K2.
• Saamaynta ka-hortagga ee butyric acid, nicotinamide, calcium glucarate oo keliya ama isku-darka inta lagu jiro 7, 12-dimethylbenz (a) anthracene waxay keentay burogenesis maqaarka jiirka iyada oo loo marayo qaabaynta K-Ras-PI3K-AKTpathway iyo micro RNA-yada la xidhiidha.
• Curcumin waxay joojisaa koritaanka iyada oo loo marayo marinka Wnt/β-catenin ee unugyada kansarka sanbabada ee aan unugyada yaryar.
• Faytamiin C wuxuu xoojiyaa isbeddellada epigenetic ee ay keentay 5-azacytidine iyo xiritaanka wareegga unugyada ee khadadka unugyada kansarka hepatocellular HLE iyo Huh7.
• Lycopene waxay si kala duwan u keentaa su'aal iyo apoptosis ee khadadka unugyada kansarka qanjirka 'prostate' ee ka jawaaba androgen-ka.