Cuntooyinka loogu talagalay Kansarka Sarcomatoid ee Kansarka Sanbabada!

Hordhac

Cuntooyinka loogu talagalay kansarka sanbabada ee Sarcomatoid ee Kansarka Sanbabada waa in loo gaaryeelaa qof kasta oo waa in sidoo kale la qabsadaa marka daaweynta kansarka ama isbeddelka hidda-socodka burada. Shakhsiyaynta iyo la qabsiga waa in ay tixgelisaa dhammaan maaddooyinka firfircoon ama bioactives ee ku jira cuntooyinka kala duwan marka loo eego bayooloojiyada unugyada kansarka, genetics, daawaynta, xaaladaha qaab nololeedka iyo doorbidka cuntada. Sidaa darteed iyadoo nafaqadu ay tahay mid ka mid ah go'aamada aadka muhiimka u ah bukaanka kansarka iyo qofka halista ugu jira kansarka inuu sameeyo - sida loo doorto cuntooyinka uu cuno maaha hawl fudud.

Kansarka Sarcomatoid waa nooc kansar ah oo xoog badan oo naadir ah oo saameyn kara xubnaha kala duwan, oo ay ku jiraan sambabada, kelyaha, prostate, kaadiheysta, beerka, maqaarka, iyo madaxa iyo qoorta. Baadhista saxda ah iyo fahamka kansarkan waxaa caawiyay tilmaamo cilmi-nafsi, kuwaas oo qeexaya sifooyinka iyo sifooyinka kansarka sarcomatoid. Calaamadaha kansarka sanbabada way kala duwanaan karaan iyadoo ku xiran xubinta ay saameysay laakiin waxaa ku jiri kara xanuun, barar, iyo dhibaatooyin xagga neefsiga ah marka laga hadlayo kansarka sanbabada ee sarcomatoid. Heerarka badbaadada kansarka sarcomatoid waa ku kala duwan yihiin iyadoo ku saleysan burada gaarka ah iyo heerka cudurka. Daawaynta kansarka sarcomatoid waxay inta badan ku lug leedahay habab kala duwan, oo ay ku jiraan qalliin, kiimoterabi, iyo immunotherapy, taas oo ku xidhan kiis gaar ah. Nidaamka koodka ICD-10 wuxuu awood u siinayaa dukumeenti ku habboon iyo kala soocida kansarka sarcomatoid ee diiwaannada caafimaadka. Immunohistochemistry ayaa door ka ciyaara xaqiijinta ogaanshaha iyo hagida go'aamada daawaynta, gaar ahaan kansarka sanbabada ee sarcomatoid. Cilmi-baaris joogto ah oo ku saabsan isbeddellada suurtagalka ah iyo daawaynta la beegsanayo waxay gacan ka geysataa hagaajinta fursadaha daawaynta ee kansarkan daran. Intaa waxaa dheer, tallaalka difaaca jirka ayaa laga yaabaa inuu ballan qaado sidii dariiqa daawaynta ee suurtogalka ah ee kansarka sarcomatoid. Ka warqabka heerarka badbaadada kala duwan ee kansarka sarcomatoid ee xubnaha kala duwan, sida kaadiheysta iyo sambabada, ayaa muhiim u ah bukaanada iyo bixiyeyaasha daryeelka caafimaadka. Guud ahaan, hab dhamaystiran oo daaweynta iyo horumarinta joogtada ah ee cilmi-baarista ayaa gacan ka geysta natiijooyin wanaagsan oo loogu talagalay shakhsiyaadka qaba kansarka sarcomatoid.

Kansarka Sarcomatoid ee Kansarka Sambabada miyay muhiim u tahay waxa khudaarta, miraha, lawska, iniinaha uu qofku cuno?

Su'aasha nafaqeynta ee aadka u badan ee ay weydiiyaan bukaannada kansarka iyo shakhsiyaadka halista ugu jira hidde-sidaha kansarka waa - kansarka sida Sarcomatoid Carcinoma Of The Lung miyay muhiim tahay cuntooyinka aan cuno iyo kuwa aanan samayn? Mise haddii aan raaco cunto ku salaysan dhirta waa taas ku filan kansarka sida Sarcomatoid Carcinoma Of The Lung?

Tusaale ahaan macne ma leedahay haddii Calabash khudaarta la isticmaalo in ka badan marka loo eego basbaaska (c. Frutescens)? Miyay wax farqi ah samaynaysaa haddii miraha Japanese Persimmon laga doorbido Raspberry Cas? Sidoo kale haddii xulashooyin la mid ah loo sameeyo nuts/abuurka sida Hazelnut-ka Caadiga ah ee Chestnut Yurub iyo garaacyada sida Adzuki Bean oo ka sarreeya Digirta Caadiga ah. Iyo haddii waxa aan cuno ay arrintu khusayso - markaa sidee qofku u aqoonsan karaa cuntooyinka lagu taliyey Sarcomatoid Carcinoma of the Lung oo jawaab isku mid ah ma u tahay qof kasta oo leh isla ogaanshaha ama khatarta hidde-sidaha?

Haa! Cuntooyinka aad cuntid waxay ku jiraan Kansarka Sarcomatoid ee Kansarka Sambabada!

Talooyinka cuntadu waxay noqon karaan kuwo isku mid ah qof kasta oo way ka duwanaan karaan xitaa ogaanshaha isku midka ah iyo khatarta hidda-socodka.

Dhammaan cuntooyinka ( khudaarta, miraha, lawska, iniinaha, garaaca, saliidaha iwm.) iyo kaabayaasha nafaqadu waxay ka kooban yihiin wax ka badan hal walxo molecular ama bio-actives oo qiyaas iyo tiro kala duwan leh. Walax kasta oo firfircooni waxay leedahay hab u gaar ah oo wax qabad - kaas oo noqon kara firfircooni ama xannibaadda dariiqyada biochemical ee kala duwan. Cuntooyinka si fudud loo sheegay iyo kaabisyada lagu taliyay waa kuwa aan keenin korodhka wadayaasha molecular ee kansarka laakiin la yareeyo. Haddii kale cuntooyinkaas waa inaan lagu talin. Cuntooyinka waxaa ku jira maaddooyin badan oo firfircoon - markaa marka la qiimeynayo cuntooyinka iyo kaabayaasha waxaad u baahan tahay inaad tixgeliso saameynta dhammaan maaddooyinka firfircoon si wadajir ah halkii aad ka ahaan lahayd mid gaar ah.

Tusaale ahaan Japanese Persimmon waxay ka kooban tahay maaddooyin firfircoon Apigenin, Curcumin, Myricetin, Protocatechuic Acid, Daidzein. Raspberry-ka cas waxa uu ka kooban yahay maaddooyin firfircoon Curcumin, Ellagic Acid, Protocatechuic Acid, Daidzein, Formononetin iyo laga yaabo kuwa kale.

Khalad caadi ah oo la sameeyo marka la go'aaminayo oo la dooranayo cuntooyinka loo cuno Kansarka Sarcomatoid ee Sanbabada - waa in la qiimeeyo oo kaliya maaddooyinka firfircoon ee la doortay ee ku jira cuntooyinka oo la iska indhatiro inta kale. Sababtoo ah maaddooyinka kala duwan ee firfircoon ee ku jira cuntooyinka ayaa laga yaabaa inay saameyn liddi ku ah ku yeeshaan darawalada kansarka - ma qaadan kartid maaddooyinka firfircoon ee cuntooyinka iyo kaabayaasha si aad u go'aansato nafaqeynta Sarcomatoid Carcinoma Of The Lung.

HAA – DOORASHOOYINKA CUNTADA EE KANSARKA WAXAY U TAAGAN YAHAY. GO'AANKA NAFAQADA waa in ay tixgeliyaan dhammaan walxaha firfircoon ee CUNTADA.

Xirfadaha Loogu Baahan Yahay Nafaqaynta Shakhsiyaynta ee Kansarka Sarcomatoid ee Sanbabada?

Nafaqada shakhsi ahaaneed ee kansarrada sida Sarcomatoid Kansarka Sanbabada wuxuu ka kooban yahay cuntooyin / kaabis lagu taliyey; Cuntooyinka aan lagu talin/kabka tusaale ahaan cunto karinta kuwaas oo mudnaanta siiya isticmaalka cuntooyinka lagu taliyay. Tusaale nafaqeynta gaarka ah ayaa tan lagu arki karaa link.

Go'aaminta cuntooyinka lagu taliyay iyo kuwa aan lagu talin waa mid aad u adag, oo u baahan khibrad Sarcomatoid Carcinoma Of The Lung biology, sayniska cuntada, genetics, biochemistry oo ay weheliso faham wanaagsan oo ku saabsan sida daawaynta kansarku u shaqeyso iyo baylahda la xidhiidha kuwaas oo daaweyntu ay joojin karto waxtarka.

Khibradda UGU YAR EE AQOONTA EE LOO BAAHAN YAHAY NAFAQADA SHAQSIYADEEDKA KANSARKA WAA: NOLOLIGA KANSARKA, CUNTADA CUNTADA, DAAWAYNTA KANSARKA IYO HIDDAHA HIDDAHA.

Astaamaha kansarka sida Sarcomatoid Carcinoma Of The Lung

Dhammaan kansarrada sida Sarcomatoid Kansarka Sambabada waxaa lagu tilmaami karaa nooc gaar ah oo ah dariiqooyin kiimikaad - dariiqooyinka saxiixa ee Sarcomatoid Carcinoma Of The Lung. Dariiqooyin kiimikaad sida isbaarada wareegga unugyada, PI3K-AKT-MTOR Signaling, Apoptosis, RAS-RAF Signaling waa qayb ka mid ah qeexida saxiixa Sarcomatoid Kansarka Sanbabada. Hidde-sideyaasha kansarku qof walba wuu ka duwanaan karaa sidaas darteed saxiixooda gaarka ah ee kansarku wuxuu noqon karaa mid gaar ah.

Daawaynta waxtarka u leh kansarka sanbabada ee Sarcomatoid waxay u baahan yihiin inay ogaadaan dariiqooyinka biochemical ee la xidhiidha saxeexa bukaan kasta oo kansar ah iyo shakhsi ahaan khatarta hidde-sidaha. Sidaa darteed daawayn kala duwan oo leh habab kala duwan oo ficil ah ayaa waxtar u leh bukaanada kala duwan. Si la mid ah iyo sababo la mid ah cuntooyinka iyo kaabista waxay u baahan yihiin in shaqsi kasta loo gaaryeelo. Sidaa awgeed cuntooyinka iyo kaabista qaar ayaa lagula taliyaa Sarcomatoid Carcinoma Of The Lung marka la qaadanayo daawaynta kansarka Abemaciclib, cuntooyinka iyo kaabista qaarna laguma talinayo.

Ilaha sida cBioPortal iyo qaar kale oo badan ayaa bixiya xogta bukaan-socodka ee aan la magacaabin ee laga helay tijaabooyinka bukaan-socodka ee dhammaan calaamadaha kansarka. Xogtan waxay ka kooban tahay tafaasiisha daraasadda tijaabada caafimaad sida cabbirka saamiga / tirada bukaannada, kooxaha da'da, jinsiga, qowmiyadda, daawaynta, goobta burooyinka iyo isbeddellada hidde-sidaha.

TP53, RNF43, MET, NRAS iyo KRAS ayaa ah kuwa ugu sareeya ee la soo sheegay hiddo-wadaha ee kansarka sanbabada ee Sarcomatoid. TP53 ayaa lagu soo warramey 45.5 % bukaanada matala dhamaan tijaabooyinka kiliinikada. RNF43 ayaa lagu soo warramey 18.2 %. Isku darka xogta bukaanka ee dadweynaha ayaa daboolaya da'aha laga bilaabo ilaa . 60.0 % xogta bukaanka waxaa loo aqoonsaday inay yihiin rag. Kansarka Sarcomatoid ee bayoolajiga sambabada oo ay weheliso hidde-sideyaasha la soo sheegay ayaa si wada jir ah u qeexaya dariiqooyinka biochemical ee saxeexa dadweynaha ee kansarkan. Haddii genetics-ka burada kansarka shakhsi ahaaneed ama hiddo-wadaha ka qaybqaata khatarta sidoo kale waa la yaqaan markaa waa in sidoo kale loo isticmaalo shakhsiyaynta nafaqada.

Dookhyada nafaqeynta waa in ay iswaafaqaan shaqsi walba saxiixiisa.

Cuntada iyo Kaabayaasha Sarcomatoid Kansarka Sambabada

Bukaanka Kansarka

Bukaanjiifka kansarka ee ku jira daawaynta ama daryeelka palliative waxay u baahan yihiin inay go'aan ka gaadhaan cuntada iyo kaabista - kaloriinta cuntada ee loo baahan yahay, maaraynta waxyeellooyin kasta oo daawaynta iyo sidoo kale hagaajinta maaraynta kansarka. Dhammaan cuntooyinka dhirta ku salaysan maaha kuwo siman oo doorashada iyo kala horraysiinta cuntooyinka kuwaas oo shakhsi ahaan loo habeeyey oo loo habeeyey daawaynta kansarka ee socota waa muhiim oo dhib badan. Waa kuwan tusaalayaal siinaya tilmaamo lagu samaynayo go'aannada nafaqada.

Dooro CALABASH khudaar ama basbaas (C. FRUTESCENS)?

Calabash khudradda waxaa ku jira waxyaabo badan oo firfircoon ama bioactives sida Apigenin, Curcumin, Lycopene, Myricetin, Protocatechuic Acid. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida DNA Dayactir, Calaamadaynta MAPK, Calaamadaynta PI3K-AKT-MTOR iyo Isbaarooyinka Wareegga Unugyada iyo kuwa kale. Calabash waxaa lagula taliyaa Sarcomatoid Carcinoma of the Lung marka daawaynta kansarka ee socota ay tahay Abemaciclib. Tani waa sababta oo ah Calabash waxay wax ka beddeshaa dariiqyada biochemical ee si cilmiyeysan loo soo sheegay si loo dareemo saameynta Abemaciclib.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee ku jira basbaaska khudradda (c. Frutescens) waa Apigenin, Curcumin, Lycopene, Myricetin, Protocatechuic Acid. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida Dayactirka DNA-da, Calaamadaynta MAPK iyo Isbaarooyinka Wareegga Unugyada iyo kuwa kale. Basbaas (c. Frutescens) laguma talinayo Sarcomatoid Kansarka Sanbabada marka daawaynta kansarka ee socota waa Abemaciclib sababtoo ah waxay wax ka beddeshaa dariiqyada biochemical ee ka dhigaya daaweynta kansarku mid adkaysi u leh ama aan ka jawaabin.

Kaabashka khudaarta ah waxaa lagula taliyaa basbaaska (C. FRUTESCENS) oo loogu talagalay Kansarka Sarcomatoid ee sambabada iyo daawaynta Abemaciclib.

Dooro midhaha raspberry cas ama PERSIMMON JAPANIS?

Khudradu waxay ka kooban tahay waxyaabo badan oo firfircoon ama bioactives sida Curcumin, Ellagic Acid, Protocatechuic Acid, Daidzein, Formononetin. Maaddooyinkan firfircooni waxay wax ka qabtaan dariiqooyin kiimikaad oo kala duwan sida Calaamadaynta Sababta Kobaca, Calaamadaynta MAPK iyo PI3K-AKT-MTOR Signaling iyo kuwa kale. Raspberry cas waxaa lagula taliyaa Sarcomatoid Kansarka Sambabada marka daawaynta kansarka socota ay tahay Abemaciclib. Tani waa sababta oo ah Raspberry Cas ayaa wax ka beddelaya dariiqyada biochemical ee si cilmiyeysan loo soo sheegay si loo dareemo saameynta Abemaciclib.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee ku jira miraha Japanese Persimmon waa Apigenin, Curcumin, Myricetin, Protocatechuic Acid, Daidzein. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida Dayactirka DNA-ga iyo Isbaarooyinka Wareegga Unugyada iyo kuwa kale. Japanese Persimmon laguma talinayo Sarcomatoid Kansarka Sanbabada marka daawaynta kansarka ee socota ay tahay Abemaciclib sababtoo ah waxay wax ka beddeshaa dariiqyada biochemical ee ka dhigaya daaweynta kansarku mid adkaysi u leh ama ka jawaabi kara.

FRUIT RED Raspberryry ayaa lagula taliyaa PERSIMMON JAPAN ee loogu talagalay Kansarka Sarcomatoid ee sambabada iyo daawaynta Abemaciclib.

Dooro Nut COMMON HAZELNUT ama XARUNTA YURUB?

Hazelnut-ka caadiga ah waxa ku jira maaddooyin badan oo firfircoon ama bioactives sida Curcumin, Lycopene, Myricetin, Protocatechuic Acid, Daidzein. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida MAPK Signaling iyo Koontaroolada wareegga unugyada iyo kuwa kale. Hazelnut-ka caadiga ah waxaa lagula taliyaa Sarcomatoid Kansarka Sambabada marka daawaynta kansarka socota ay tahay Abemaciclib. Tani waa sababta oo ah Hazelnut Common waxay wax ka beddeshaa dariiqyada biochemical ee si cilmiyeysan loo soo sheegay si loo dareemo saameynta Abemaciclib.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee Chestnut Yurub waa Apigenin, Curcumin, Ellagic Acid, Myricetin, Protocatechuic Acid. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida Dayactirka DNA-ga iyo Isbaarooyinka Wareegga Unugyada iyo kuwa kale. Chestnut Yurub laguma talinayo Sarcomatoid Kansarka Sambabada marka daawaynta kansarka ee socota ay tahay Abemaciclib sababtoo ah waxay wax ka beddeshaa dariiqyada biochemical ee ka dhigaya daaweynta kansarku mid adkaysi u leh ama ka jawaabi kara.

HAZELNUT caam ah ayaa lagula talinayaa laabta Yurub ee kansarka sanbabada iyo daawaynta Abemaciclib.

Shakhsiyaadka leh Khatarta Hidde ee Kansarka

Su'aasha ay weydiiyaan shakhsiyaadka leh khatarta hidde-sidaha ee kansarka sanbabada ee Sarcomatoid Kansarka Sambabada ama taariikhda qoyska waa "Maxaan Cunnaa si ka duwan kii hore?" iyo sida ay tahay inay doortaan cuntooyinka iyo kaabista si loo maareeyo khatarta cudurka. Maadaama khatarta kansarku aanay jirin wax la qaban karo marka la eego daawaynta - go'aamada cuntooyinka iyo kaabista ayaa noqda mid muhiim ah iyo mid ka mid ah waxyaallaha aadka u yar ee la qaban karo. Dhammaan cuntooyinka dhirta ku salaysan maaha kuwo siman oo ku salaysan hidde-sidaha la aqoonsaday iyo saxeexa dariiqa - doorashooyinka cuntada iyo kaabista waa in la shakhsiyeeyo.

Dooro Qudaar GIANT BUTTERBUR ama KOHLRABI?

Khudaarta Giant Butterbur waxay ka kooban tahay waxyaabo badan oo firfircoon ama bioactives sida Curcumin, Delphinidin, Apigenin, Lycopene, Myricetin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida RAS-RAF Signaling, Signaling Factor Growth, MAPK Signaling iyo MYC Signaling iyo kuwa kale. Giant Butterbur waxaa lagula talinayaa halista Sarcomatoid Kansarka Sanbabada marka khatarta hidde-sidaha la xiriirta ay tahay KRAS. Tani waa sababta oo ah Giant Butterbur waxay kordhisaa dariiqyada biochemical ee ka soo horjeeda wadayaasha saxeexa.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee khudradda Kohlrabi waa Quercetin, Curcumin, Delphinidin, Formononetin, Lupeol. Maaddooyinkan firfircooni waxay wax ka qabtaan dariiqooyin kiimikaad oo kala duwan sida Cadaadiska Oxidative iyo kuwa kale. Kohlrabi laguma talinayo marka halista Sarcomatoid Kansarka Sanbabada marka halista hidde-sidaha la xidhiidha ay tahay KRAS sababtoo ah waxay kordhisaa dariiqooyinka saxeexa.

BUTTERBUR WAYN OO khudaar ah ayaa lagula taliyaa KOHLRABI HALISTA KRAS EE KANSARKA.

Dooro Miraha NANCE ama PUMMELO?

Miraha Nance waxaa ku jira waxyaabo badan oo firfircoon ama bioactives sida Curcumin, Delphinidin, Apigenin, Myricetin, Formononetin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida RAS-RAF Signaling, Signaling Factor Growth, MAPK Signaling iyo MYC Signaling iyo kuwa kale. Nance waxaa lagula talinayaa halista Sarcomatoid Kansarka Sambabada marka khatarta hidde-sidaha la xiriirta ay tahay KRAS. Tani waa sababta oo ah Nance waxay kordhisaa dariiqyada biochemical ee ka soo horjeeda darawaliinta saxeexa.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee ku jira miro Pummelo waa Quercetin, Curcumin, Delphinidin, Apigenin, Lycopene. Maaddooyinkan firfircooni waxay wax ka qabtaan dariiqooyin kiimikaad oo kala duwan sida Cadaadiska Oxidative iyo kuwa kale. Pummelo laguma talinayo marka halista Sarcomatoid Kansarka Sanbabada marka khatarta hidde-sidaha ee la xidhiidha KRAS ay tahay sababtoo ah waxay kordhisaa dariiqooyinka saxeexa.

FRUIT NANCE waxaa lagula talinayaa PUMMELO oo loogu talagalay khatarta hidda-socodka KRAS ee kansarka.

Dooro lowska BUTTERNUT ama BRAZIL NUT?

Butternut wuxuu ka kooban yahay waxyaabo badan oo firfircoon ama bioactives sida Curcumin, Delphinidin, Apigenin, Lycopene, Myricetin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida Apoptosis, Calaamadaynta MAPK, Isbaarada Wareegga Unugyada iyo Calaamadaynta MYC iyo kuwa kale. Butternut ayaa lagula talinayaa halista Sarcomatoid Kansarka Sanbabada marka khatarta hidde-sidaha la xiriirta ay tahay KRAS. Tani waa sababta oo ah Butternut waxay kordhisaa dariiqyada biochemical ee ka soo horjeeda wadayaasha saxiixa.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee Brazil nuts waa Ellagic Acid, Curcumin, Delphinidin, Formononetin, Lupeol. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida RAS-RAF Signaling, PI3K-AKT-MTOR Signaling iyo Oxidative Stress iyo kuwa kale. Nut Brazil laguma talinayo marka halista Sarcomatoid Kansarka Sanbabada marka khatarta hidde-sidaha la xiriirta ay tahay KRAS sababtoo ah waxay kordhisaa dariiqooyinka saxiixa.

BUTTERNUT ayaa lagula taliyaa BRAZIL lowska ee khatarta hidda-socodka KRAS ee kansarka.

In Gabagabo

Cuntooyinka iyo Kaabayaasha la doortay waa go'aamo muhiim u ah kansarka sida Sarcomatoid Carcinoma Of The Lung. Kansarka Sarcomatoid ee Bukaannada Sambabada iyo shakhsiyaadka leh khatarta hidde-sidaha had iyo jeer waxay qabaan su'aashan: "Waa maxay cuntooyinka iyo nafaqooyinka nafaqada ee lagu taliyey aniga iyo kuwa aan ahayn?" Waxaa jira aaminsanaan guud oo ah fikrad khaldan oo ah in dhammaan cuntooyinka dhirta ku salaysan ay faa'iido yeelan karaan ama aysan ahayn laakiin aan waxyeello lahayn. Cuntooyinka qaarkood iyo kaabisyada qaarkood waxay faragelin karaan daawaynta kansarka ama waxay kor u qaadi karaan wadayaasha dariiqyada molecular ee kansarka.

Waxaa jira noocyo kala duwan oo tilmaamayaasha kansarka sida Sarcomatoid Carcinoma Of The Lung, mid kasta oo leh hidde-sidaha burooyinka kala duwan oo leh kala duwanaansho genomic dheeraad ah oo qof kasta ah. Intaa waxaa dheer daawaynta kansar kasta iyo kiimoterabi kasta waxay leeyihiin hab wax-qabad oo gaar ah. Cunto kasta sida Calabash waxa ay ka kooban tahay tirooyin kala duwan oo noole noolayaal ah oo tirooyin kala duwan leh, kuwaas oo saamayn ku leh noocyo kala duwan oo kala duwan oo ah dariiqyada biochemical. Qeexida nafaqeynta shakhsi ahaaneed waa talooyinka cuntada ee gaarka ah ee tilmaamaya kansarka, daawaynta, genetics, qaab nololeedka iyo arrimo kale. Go'aannada shakhsiyaynta nafaqada ee kansarka waxay u baahan yihiin aqoonta bayoolajiga kansarka, sayniska cuntada iyo fahamka daaweynta kemotherabi ee kala duwan. Ugu dambeyntii marka ay jiraan isbeddel daaweyn ama genomics cusub ayaa la aqoonsaday - shakhsiyeynta nafaqeynta waxay u baahan tahay dib-u-qiimeyn.

Xalka shakhsiyaynta nafaqeynta ee addon ayaa ka dhigaysa go'aan qaadashada mid fudud oo meesha ka saaraysa dhammaan malo-awaalka ka jawaabaya su'aasha, "Cunto noocee ah ayaan dooran karaa ama ma dooran karaa Sarcomatoid Kansarka Sanbabada?". Kooxda edbinta badan ee addon waxaa ka mid ah dhakhaatiirta kansarka, saynisyahano caafimaad, injineerada software iyo saynisyahano xogta.

tixraacyada

• Tmb Mskcc 2018
• Muuqaalka is-beddelka ee kansarka dheef-shiid kiimikaadka ayaa shaaca ka qaaday isku xigxiga mustaqbalka ee bukaan-socodka ee 10,000 bukaan.
• Saamaynta ka-hortagga ee butyric acid, nicotinamide, calcium glucarate oo keliya ama isku-darka inta lagu jiro 7, 12-dimethylbenz (a) anthracene waxay keentay burogenesis maqaarka jiirka iyada oo loo marayo qaabaynta K-Ras-PI3K-AKTpathway iyo micro RNA-yada la xidhiidha.
• Faytamiin C waxa uu dila unugyada kansarka qanjirka tayroodhka iyada oo loo marayo ka hortagga ROS-ku-tiirsanaanta ee MAPK/ERK iyo PI3K/AKT dariiqooyin kala duwan.
• Saamaynta xakamaynta ee Hibiscus protocatechuic acid ee horumarinta burooyinka ee maqaarka jiirka.
• Lycopene waxay si kala duwan u keentaa su'aal iyo apoptosis ee khadadka unugyada kansarka qanjirka 'prostate' ee ka jawaaba androgen-ka.
• Kicinta soo-dhoweynta ku-meel-gaarka ah ee suurtagalka ah ee vanilloid nooca 1 (TRPV1) ee capsaicin waxay keenaysaa Fas/CD95 apoptosis dhexdhexaadin ah ee unugyada kansarka kaadi mareenka hab ku tiirsan ATM.