Cuntooyinka loogu talagalay Kansarka Unugyada Kelyaha ee Aan Aan Cad Cad!

Hordhac

Cuntooyinka loogu talagalay Kansarka Unugyada Kansarka Unugyada Kelyaha ee Aan-caddeyn waa in loo shakhsiyeeyaa qof kasta waana in ay la qabsadaan marka daawaynta kansarka ama hidde-sidaha buradu ay isbeddelaan. Shakhsiyaynta iyo la qabsiga waa in ay tixgeliyaan dhammaan maaddooyinka firfircoon ama bioactives ee ku jira cuntooyinka kala duwan marka loo eego bayooloojiyada unugyada kansarka, genetics, daawaynta, xaaladaha qaab nololeedka iyo doorbidka cuntada. Sidaa darteed iyada oo nafaqadu ay tahay mid ka mid ah go'aamada aadka muhiimka u ah bukaanka kansarka iyo qofka khatarta ugu jira kansarka inuu sameeyo - sida loo doorto cuntooyinka uu cuno maaha hawl fudud.

Kansarka unugyada cad cad waa nooc kansar ah oo ku dhici kara xubnaha kala duwan, sida kelyaha, ugxan-sidaha, endometrium, afka ilmo-galeenka, iyo sambabada. Tilmaan-bixinnada cilmi-nafsiga waxay bixiyaan macluumaad qiimo leh oo ku saabsan sifooyinka kala duwan ee unugyada burooyinka ee kansarka unugyada cad. Kansarka unugyada nadiifka ah ee kelyaha, kansarka noocaan ah wuxuu inta badan saameeyaa kelyaha. Ogaanshaha saxda ah iyo koodka caafimaad ee saxda ah iyadoo la adeegsanayo koodka ICD-10 ee ku habboon ayaa muhiim u ah dukumentiyada. Ikhtiyaarada daawaynta ee kansarka unugyada cad waxaa ka mid noqon kara qalliin, daawaynta shucaaca, kiimoterabiga, iyo daawaynta la beegsaday. Saadaasha iyo heerarka badbaadada ee kansarka unugyada cad waxay ku xiran yihiin arrimo kala duwan, oo ay ku jiraan heerka iyo heerka burada. Saadaasha waa ku kala duwanaan kartaa xubin ilaa xubin kale. Cilmi-baadhista socota ayaa sii wadda si ay u wanaajiso fahamkayaga iyo daawaynta kansarka unugyada cad. Markay xog-ogaal u noqdaan oo ay raadsadaan daryeel caafimaad oo habboon, shakhsiyaadka qaba kansarka unugyada cad cad waxay wanaajin karaan xeeladahooda daawaynta waxayna wanaajin karaan fursadahooda natiijooyin guul leh iyo badbaado mustaqbalka fog ah.

Kansarka Unugyada Kelyaha ee Aan-caddeyn miyay muhiim u tahay khudaarta, miraha, lawska, iniinaha uu qofku cuno?

Su'aasha nafaqeynta ee aadka u badan ee ay weydiiyaan bukaannada kansarka iyo shakhsiyaadka halista ugu jira hidde-sidaha kansarka waa - kansarka sida Kansarka unugyada aan caddayn ee Kelyaha macno ma u leeyahay cuntooyinka aan cuno iyo kuwa aanan samayn? Mise haddii aan raaco cunto ku salaysan geedka ma ku filan tahay kansarka sida Kansarka Unugyada Kelyaha ee Aan-caddeyn?

Tusaale ahaan miyay muhiim tahay haddii khudradda Globe Artichoke la isticmaalo in ka badan marka loo eego Pokeweed American? Miyay wax farqi ah samaynaysaa haddii midho berde laga door bidayo Plantain Faransiis? Sidoo kale haddii xulashooyin la mid ah loo sameeyo lawska/abuurka sida Hazelnut-ka caadiga ah ee xabadka iyo garaaca sida Broad Bean over Lentils. Oo haddii waxa aan cunaa ay arrintu khusayso - haddaba sidee loo aqoonsan karaa cuntooyinka lagu taliyay Kansarka Unugyada Kelyaha ee Aan-caddeyn oo ma isku mid bay u tahay qof kasta oo leh isla ogaanshaha ama khatarta hidde-sidaha?

Haa! Cuntooyinka aad cuntid waxay udub dhexaad u yihiin Kansarka Unugyada Kelyaha ee Aan-caddeyn!

Talooyinka cuntadu waxay noqon karaan kuwo isku mid ah qof kasta oo way ka duwanaan karaan xitaa ogaanshaha isku midka ah iyo khatarta hidda-socodka.

Dhammaan cuntooyinka ( khudaarta, miraha, lawska, iniinaha, garaaca, saliidaha iwm.) iyo kaabayaasha nafaqadu waxay ka kooban yihiin wax ka badan hal walxo molecular ama bio-actives oo qiyaas iyo tiro kala duwan leh. Walax kasta oo firfircooni waxay leedahay hab u gaar ah oo wax qabad - kaas oo noqon kara firfircooni ama xannibaadda dariiqyada biochemical ee kala duwan. Cuntooyinka si fudud loo sheegay iyo kaabisyada lagu taliyay waa kuwa aan keenin korodhka wadayaasha molecular ee kansarka laakiin la yareeyo. Haddii kale cuntooyinkaas waa inaan lagu talin. Cuntooyinka waxaa ku jira maaddooyin badan oo firfircoon - markaa marka la qiimeynayo cuntooyinka iyo kaabayaasha waxaad u baahan tahay inaad tixgeliso saameynta dhammaan maaddooyinka firfircoon si wadajir ah halkii aad ka ahaan lahayd mid gaar ah.

Tusaale ahaan berdaha waxaa ku jira maaddooyin firfircoon oo Quercetin, Curcumin, Isoliquiritigenin, Formononetin, Lycopene. Plantain-ka Faransiisku waxa uu ka kooban yahay maaddooyin firfircoon oo Quercetin, Curcumin, Apigenin, Myricetin, Isoliquiritigenin iyo suurtogal ah kuwa kale.

Khalad caadi ah oo la sameeyo marka la go'aaminayo oo la dooranayo cuntooyinka la cuno ee Kansarka Unugyada Kelyaha ee Aan-caddeyn - waa in la qiimeeyo oo kaliya maaddooyinka firfircoon ee la doortay ee ku jira cuntooyinka oo la iska indho tiro inta kale. Sababtoo ah maaddooyinka kala duwan ee firfircoon ee ku jira cuntooyinka ayaa laga yaabaa inay saameyn iska soo horjeeda ku yeeshaan darawalada kansarka - ma qaadan kartid maaddooyinka firfircoon ee cuntooyinka iyo kaabayaasha si loo gaaro go'aanka nafaqeynta ee Kansarka Unugyada Kelyaha ee Aan-caddeyn.

HAA – DOORASHOOYINKA CUNTADA EE KANSARKA WAXAY U TAAGAN YAHAY. GO'AANKA NAFAQADA waa in ay tixgeliyaan dhammaan walxaha firfircoon ee CUNTADA.

Xirfadaha Looga Baahan Yahay Nafaqaynta Shakhsiyaynta ee Kansarka Unugyada Kelyaha ee Aan Cadayn?

Nafaqada shakhsi ahaaneed ee kansarka sida Kansarka Unugyada Kelyaha ee Aan-caddeyn wuxuu ka kooban yahay cuntooyin/kaabyo lagu taliyey; Cuntooyinka aan lagu talin/kabka tusaale ahaan cunto karinta kuwaas oo mudnaanta siiya isticmaalka cuntooyinka lagu taliyay. Tusaale nafaqeynta gaarka ah ayaa tan lagu arki karaa link.

Go'aaminta cuntooyinka lagu taliyay iyo in kale waa mid aad u adag, oo u baahan khibrad ku saabsan baayoolojiga unugyada Kansarka Unugyada Kelyaha ee Aan-caddayn, sayniska cuntada, genetics, biochemistry oo ay weheliso faham wanaagsan oo ku saabsan sida daawaynta kansarku u shaqeyso iyo baylahda la xidhiidha kuwaas oo daawadu ay joojin karto waxtarka.

Khibradda UGU YAR EE AQOONTA EE LOO BAAHAN YAHAY NAFAQADA SHAQSIYADEEDKA KANSARKA WAA: NOLOLIGA KANSARKA, CUNTADA CUNTADA, DAAWAYNTA KANSARKA IYO HIDDAHA HIDDAHA.

Astaamaha kansarrada sida Kansarka Unugyada Kelyaha ee Aan-caddeyn

Dhammaan kansarrada sida Kansarka Unugyada Kelyaha ee Aan-caddeyn waxa lagu gartaa hab gaar ah oo ah dariiqooyin kiimikaad - dariiqooyinka saxeexa ee Kansarka Unugyada Kelyaha ee Aan-caddeyn. Dariiqooyin kiimikaad sida MAPK Signaling, RAS-RAF Signaling, PI3K-AKT-MTOR Signaling, Gaadiidka Molecule Yaryar waa qayb ka mid ah qeexida saxeexa ee Kansarka Unugyada Kelyaha ee Aan Cad Cad. Hidde-sideyaasha kansarku qof walba wuu ka duwanaan karaa sidaas darteed saxiixooda gaarka ah ee kansarku wuxuu noqon karaa mid gaar ah.

Daawaynta waxtarka u leh Kansarka Unugyada Kelyaha ee Aan-caddeyn waxay u baahan yihiin inay ogaadaan dariiqooyinka biochemical ee la xidhiidha saxeexa bukaan kasta oo kansar ah iyo shakhsi ahaan khatarta hidde-sidaha. Sidaa darteed daawayn kala duwan oo leh habab kala duwan oo ficil ah ayaa waxtar u leh bukaanada kala duwan. Si la mid ah iyo sababo la mid ah cuntooyinka iyo kaabista waxay u baahan yihiin in shaqsi kasta loo gaaryeelo. Sidaa awgeed cuntooyinka iyo kaabista qaar ayaa lagula taliyaa Kansarka Unugyada Kelyaha ee Aan-cadayn marka la qaadanayo daawaynta kansarka Sorafenib, iyo cuntooyinka qaarkood iyo kaabista laguma talinayo.

Ilaha sida cBioPortal iyo qaar kale oo badan ayaa bixiya xogta bukaan-socodka ee aan la magacaabin ee laga helay tijaabooyinka bukaan-socodka ee dhammaan calaamadaha kansarka. Xogtan waxay ka kooban tahay tafaasiisha daraasadda tijaabada caafimaad sida cabbirka saamiga / tirada bukaannada, kooxaha da'da, jinsiga, qowmiyadda, daawaynta, goobta burooyinka iyo isbeddellada hidde-sidaha.

TP53, MET, MUC4, SPEN iyo ARID1A ayaa ah kuwa ugu sareeya ee la soo sheegay hiddo-wadaha ee Kansarka Unugyada Kelyaha ee Aan-caddeyn. TP53 ayaa lagu soo warramey 7.9 % bukaanada mataleysa dhamaan tijaabooyinka caafimaad. MET-na waxaa lagu soo warramey 7.2 %. Isku darka xogta bukaan-socodka ee dadweynaha ayaa daboolaya da'da 25 ilaa 88. 63.4 % xogta bukaan-socodka waxaa loo aqoonsaday inay yihiin rag. Biology-ga Kansarka Unugyada Kelyaha ee Aan-caddeyn oo ay weheliso hidde-sideyaasha la soo sheegay ayaa si wada jir ah u qeexaya dariiqooyinka biochemical ee saxeexa dadweynaha ee kansarkan. Haddii genetics-ka burada kansarka shakhsi ahaaneed ama hiddo-wadaha ka qaybqaata khatarta sidoo kale waa la yaqaan markaa waa in sidoo kale loo isticmaalo shakhsiyaynta nafaqada.

Dookhyada nafaqeynta waa in ay iswaafaqaan shaqsi walba saxiixiisa.

Cuntada iyo Kaabayaasha loogu talagalay Kansarka Unugyada Kelyaha ee Aan-caddeyn

Bukaanka Kansarka

Bukaanjiifka kansarka ee ku jira daawaynta ama daryeelka palliative waxay u baahan yihiin inay go'aan ka gaadhaan cuntada iyo kaabista - kaloriinta cuntada ee loo baahan yahay, maaraynta waxyeellooyin kasta oo daawaynta iyo sidoo kale hagaajinta maaraynta kansarka. Dhammaan cuntooyinka dhirta ku salaysan maaha kuwo siman oo doorashada iyo kala horraysiinta cuntooyinka kuwaas oo shakhsi ahaan loo habeeyey oo loo habeeyey daawaynta kansarka ee socota waa muhiim oo dhib badan. Waa kuwan tusaalayaal siinaya tilmaamo lagu samaynayo go'aannada nafaqada.

Dooro khudaar GLOBE ARTICHOKE ama AMERICAN PAKEWEED?

Qudaarta Globe Artichoke waxay ka kooban tahay waxyaabo badan oo firfircoon ama bioactives sida Curcumin, Apigenin, Myricetin, Isoliquiritigenin, Formononetin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida wareegga unugga, bararka, ka jawaab celinta kulaylka iyo PI3K-AKT-MTOR Signaling iyo kuwa kale. Globe Artichoke waxaa lagula taliyaa Kansarka Unugyada Kelyaha ee Aan-caddeyn marka daawaynta kansarka ee socota ay tahay Sorafenib. Tani waa sababta oo ah Globe Artichoke waxay wax ka beddeshaa dariiqyada biochemical ee si cilmiyeysan loo soo sheegay si loo dareemo saameynta Sorafenib.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee ku jira khudradda Pokeweed American waa Quercetin, Curcumin, Apigenin, Myricetin, Isoliquiritigenin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimiko oo kala duwan sida Epithelial ilaa Mesenchymal Transition, Heat Stress Response, Oxidative Stress iyo kuwa kale. Pokeweed American laguma talinayo Kansarka Unugyada Kelyaha ee Aan-caddeyn marka daawaynta kansarka ee socota ay tahay Sorafenib sababtoo ah waxay wax ka beddeshaa dariiqyada biochemical ee ka dhigaya daaweynta kansarku mid adkaysi u leh ama ka jawaabi kara.

ARTICHOKE GLOBE QUDADAY AYAA LAGULA TALAGALINAYAA PAKEWEED MAREYKAN EE KAALIDA KALIYADA EE KAALINTA CELIN EE AAN CADEYN IYO DAWAYNTA Sorafenib.

Dooro Miraha PLANTAIN ama berde?

Plantain French miraha waxaa ku jira waxyaabo badan oo firfircoon ama bioactives sida Quercetin, Curcumin, Apigenin, Myricetin, Isoliquiritigenin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida wareegga unugga, bararka, dayactirka DNA-ga iyo Microtubule Dynamics iyo kuwa kale. Plantain-ka Faransiiska waxa lagula taliyaa Kansarka Unugyada Kelyaha ee Aan-caddayn marka daawaynta kansarka ee socota ay tahay Sorafenib. Tani waa sababta oo ah Plantain Faransiisku wuxuu wax ka beddelaa dariiqyada biochemical ee si cilmiyeysan loo soo sheegay si loo dareemo saameynta Sorafenib.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee miraha miraha ah waa Quercetin, Curcumin, Isoliquiritigenin, Formononetin, Lycopene. Maaddooyinkan firfircooni waxay wax ka qabtaan dariiqooyin kiimikaad oo kala duwan sida Ka jawaab celinta Cadaadiska Kulaylka iyo Cadaadiska Oxidative iyo kuwa kale. Berdaha laguma talinayo Kansarka Unugyada Kelyaha ee Aan-caddeyn marka daawaynta kansarka ee socota ay tahay Sorafenib sababtoo ah waxay wax ka beddeshaa dariiqyada biochemical ee ka dhigaya daawaynta kansarku mid adkaysi u leh ama aan ka jawaabin.

DHIRTA FARAANSIINTA MIDHAHA AYAA LAGULA TALIYEY SHARCIGA KALIYA EE Kansarka Unugyada Aan Cadayn Iyo Daawaynta Sorafenib.

Dooro Nut COMMON HAZELNUT ama LAABKA?

Hazelnut-ka caadiga ah waxa ku jira maaddooyin badan oo firfircoon ama bioactives sida Quercetin, Curcumin, Myricetin, Isoliquiritigenin, Formononetin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida wareegga unugga, bararka, dayactirka DNA-ga iyo Microtubule Dynamics iyo kuwa kale. Hazelnut-ka caadiga ah waxa lagula taliyaa Kansarka Unugyada Kelyaha ee Aan-caddeyn marka daawaynta kansarka socota tahay Sorafenib. Tani waa sababta oo ah Hazelnut Common wuxuu wax ka beddelaa dariiqyada biochemical ee si cilmiyeysan loo soo sheegay si loo dareemo saameynta Sorafenib.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee ku jira Chestnut waa Curcumin, Ellagic Acid, Apigenin, Myricetin, Isoliquiritigenin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida DNA Repair, Epithelial ilaa Mesenchymal Transition, WNT Beta Catenin Signaling iyo Oxidative Stress iyo kuwa kale. Chestnut laguma talinayo Kansarka Unugyada Kelyaha ee Aan-caddeyn marka daawaynta kansarka ee socota ay tahay Sorafenib sababtoo ah waxay wax ka beddeshaa dariiqyada biochemical ee ka dhigaya daawaynta kansarku mid adkaysi u leh ama aan ka jawaabin.

HAZELNUT caam ah ayaa lagula taliyaa laabta iyo daawaynta Sorafenib.

Shakhsiyaadka leh Khatarta Hidde ee Kansarka

Su'aasha ay weydiiyaan shakhsiyaadka leh khatarta hidde-sidaha ee Kansarka Unugyada Unugyada Aan-caddeyn ee Kelyaha ama taariikhda qoysku waa "Maxaan Cunnaa si ka duwan kii hore?" iyo sida ay tahay inay doortaan cuntooyinka iyo kaabista si loo maareeyo khatarta cudurka. Maadaama khatarta kansarku aanay jirin wax la qaban karo marka la eego daawaynta - go'aannada cuntooyinka iyo kaabista ayaa noqda mid muhiim ah iyo mid ka mid ah wax yaabaha yar ee la qaban karo ee la samayn karo. Dhammaan cuntooyinka dhirta ku salaysan maaha kuwo siman oo ku salaysan hidde-sideyaasha la aqoonsaday iyo saxiixa dariiqa - doorashooyinka cuntada iyo kaabista waa in la shakhsiyeeyo.

Dooro Qudaar GIANT BUTTERBUR ama SWISS CHARD?

Khudaarta Giant Butterbur waxay ka kooban tahay waxyaabo badan oo firfircoon ama bioactives sida Apigenin, Curcumin, Lupeol, Daidzein, Lycopene. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida wareegga unugyada, P53 Signaling, Signaling WNT Beta Catenin iyo MYC Signaling iyo kuwa kale. Giant Butterbur waxaa lagula taliyaa halista Kansarka Unugyada Kelyaha ee Aan-caddeyn marka khatarta hidde-sidaha la xiriirta ay tahay ARID1A. Tani waa sababta oo ah Giant Butterbur waxay kordhisaa dariiqyada biochemical ee ka soo horjeeda wadayaasha saxeexa.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee khudradda Swiss Chard waa Apigenin, Curcumin, Quercetin, Lupeol, Daidzein. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida Dib-u-habaynta Matrix Extracellular Matrix iyo WNT Beta Catenin Signaling iyo kuwa kale. Swiss Chard laguma talinayo marka khatarta kalyaha ee Kansarka Unugyada Aan-caddeyn marka khatarta hidde-sidaha la xidhiidha ay tahay ARID1A sababtoo ah waxay kordhisaa dariiqyada saxiixa.

BUTTERBUR WAYN OO khudaareed ayaa lagula taliyaa SWISS CHARD ARID1A HALISTA HIDDAHA EE KANSARKA.

Dooro Miraha NANCE ama PUMMELO?

Miraha Nance waxaa ku jira waxyaabo badan oo firfircoon ama bioactives sida Apigenin, Curcumin, Lupeol, Daidzein, Phloretin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida wareegga unugyada, P53 Signaling, Signaling WNT Beta Catenin iyo MYC Signaling iyo kuwa kale. Nance waxaa lagula taliyaa halista Kansarka Unugyada Kelyaha ee Aan-caddeyn marka khatarta hidde-sidaha la xiriirta ay tahay ARID1A. Tani waa sababta oo ah Nance waxay kordhisaa dariiqyada biochemical ee ka soo horjeeda darawaliinta saxeexa.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee ku jira miro Pummelo waa Apigenin, Curcumin, Quercetin, Lupeol, Daidzein. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida WNT Beta Catenin Signaling iyo Koontaroolada wareegga unugyada iyo kuwa kale. Pummelo laguma talinayo marka khatarta Kelyaha ee Kansarka Unugyada Aan-caddeyn marka khatarta hidde-sidaha la xidhiidha ay tahay ARID1A sababtoo ah waxay kordhisaa waddooyinka saxeexa.

FRUIT NANCE waxaa lagula talinayaa PUMMELO oo loogu talagalay ARID1A khatarta hidda-socodka ee kansarka.

Dooro Nut BLACK WALNUT ama NUT BRAZIL?

Walnut madow waxaa ku jira waxyaabo badan oo firfircoon ama bioactives sida Apigenin, Curcumin, Quercetin, Ellagic Acid, Lupeol. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida Unug Wareegga, Calaamadaynta P53, Calaamadaynta MAPK iyo Isbaarooyinka Wareegga Unugyada iyo kuwa kale. Walnut Madow waxa lagula taliyaa halista Kansarka Unugyada Kelyaha ee Aan-caddeyn marka khatarta hidde-sidaha la xidhiidha ay tahay ARID1A. Tani waa sababta oo ah walnut madow waxay kordhisaa dariiqyada biochemical ee ka soo horjeeda wadayaasha saxeexa.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee Brazil nuts waa Curcumin, Ellagic Acid, Lupeol, Daidzein, Phloretin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida MAPK Signaling, Signaling WNT Beta Catenin iyo PI3K-AKT-MTOR Signaling iyo kuwa kale. Nut Brazil laguma talinayo marka khatarta Kelyaha ee Kansarka Unugyada Aan-caddeyn marka khatarta hidde-sidaha la xidhiidha ay tahay ARID1A sababtoo ah waxay kordhisaa waddooyinka saxeexa.

Walaska madow waxa lagula taliyaa BRAZIL lowska ARID1A HALISTA HIDDAHA EE KANSARKA.

In Gabagabo

Cuntooyinka iyo Kaabayaasha la doortay ayaa ah go'aamo muhiim u ah kansarka sida Kansarka Unugyada Kelyaha ee Aan- Cad. Bukaannada Kansarka Unugyada Kelyaha ee Aan-caddeyn ee Kansarka iyo shakhsiyaadka leh khatarta hidde-sidaha waxay had iyo jeer qabaan su'aashan: "Waa maxay cunnooyinka iyo kaabisyada nafaqeynta ee lagu taliyay aniga iyo kuwa aan ahayn?" Waxaa jira aaminsanaan guud oo ah fikrad khaldan oo ah in dhammaan cuntooyinka dhirta ku salaysan ay faa'iido yeelan karaan ama aysan ahayn laakiin aan waxyeello lahayn. Cuntooyinka qaarkood iyo kaabisyada qaarkood waxay faragelin karaan daawaynta kansarka ama waxay kor u qaadi karaan wadayaasha dariiqyada molecular ee kansarka.

Waxaa jira noocyo kala duwan oo calaamado kansar ah sida Kansarka Unugyada Kansarka ee Kelyaha ee aan caddayn, mid kasta oo leh hidde-sidaha burooyinka oo kala duwan oo leh kala duwanaansho genomic oo dheeraad ah oo qof kasta ah. Intaa waxaa dheer daawaynta kansar kasta iyo kiimoterabi kasta waxay leeyihiin hab wax-qabad oo gaar ah. Cunto kasta sida Globe Artichoke waxay ka kooban tahay noocyo kala duwan oo bioactives ah oo tirooyin kala duwan leh, kuwaas oo saameyn ku leh noocyo kala duwan oo kala duwan oo ah dariiqyada biochemical. Qeexida nafaqeynta shakhsi ahaaneed waa talooyinka cuntada ee gaarka ah ee tilmaamaya kansarka, daawaynta, genetics, qaab nololeedka iyo arrimo kale. Go'aannada shakhsiyaynta nafaqada ee kansarka waxay u baahan yihiin aqoonta bayoolajiga kansarka, sayniska cuntada iyo fahamka daaweynta kemotherabi ee kala duwan. Ugu dambeyntii marka ay jiraan isbeddel daaweyn ama genomics cusub ayaa la aqoonsaday - shakhsiyeynta nafaqeynta waxay u baahan tahay dib-u-qiimeyn.

Xalka shakhsiyaynta nafaqeynta ee addon ayaa ka dhigaysa go'aan qaadashada mid fudud oo meesha ka saaraysa dhammaan malo awaalka ee ka jawaabista su'aasha, "Cunto noocee ah ayaan dooran karaa ama ma dooran karaa Kansarka Unugyada Kelyaha ee Aan-caddeyn?". Kooxda edbinta badan ee addon waxaa ka mid ah dhakhaatiirta kansarka, saynisyahano caafimaad, injineerada software iyo saynisyahano xogta.

tixraacyada

• Nccrcc Genentech 2014
• Daaweynta kansarku waxay qaabaysaa muuqaalka fayow ee hematopoiesis ee clonal.
• Curcumin waxay joojisaa koritaanka iyada oo loo marayo marinka Wnt/β-catenin ee unugyada kansarka sanbabada ee aan unugyada yaryar.
• Isku-dhafka Dabiiciga ah ee Myricetin wuxuu si wax ku ool ah u cadaadiyaa horumarka xun ee Kansarka qanjirka 'prostate' iyadoo la joojinayo PIM1 iyo khalkhalgelinta isdhexgalka PIM1/CXCR4.
• Aashitada Chlorogenic waxay joojisaa fidinta waxayna keentaa apoptosis ee unugyada kansarka kelyaha ee A498 iyada oo la dhaqaajinayo dariiqa calaamadaynta PI3K/Akt/mTOR.
• Horumarka cilmi baarista ee saameynta ka hortagga kansarka ee fitamiin K2.
• Gallic acid waxay kicisaa dhaawaca DNA waxayna xakameysaa muujinta hidda-socodka hagaajinta DNA ee kansarka qanjirka 'prostate' ee unugyada PC-3.
• Faytamiin C wuxuu xoojiyaa isbeddellada epigenetic ee ay keentay 5-azacytidine iyo xiritaanka wareegga unugyada ee khadadka unugyada kansarka hepatocellular HLE iyo Huh7.
• Kicinta koritaanka unugyada adenocarcinoma sambabada sambabada ee bini'aadamka iyo unugyada epithelial-ka yar ee hawo-mareenka by beta-carotene iyada oo la adeegsanayo cAMP, PKA, CREB iyo ERK1 / 2.
• Ka-hortagga ka-hortagga saamaynta xayeysiinta ee shaaha cad iyo kafeyn ee PhIP-ku-abuuray tumorigenesis iyo muujinta beta-catenin ee jiirka.
• Geraniol, qayb ka mid ah saliidaha lagama maarmaanka ah ee dhirta, waxay dareensiisaa unugyada kansarka mindhicirka ee 5-Fluorouracil daaweynta.