Cuntooyinka loogu talagalay Pheochromocytoma iyo Paraganglioma!

Hordhac

Cuntooyinka loogu talagalay Pheochromocytoma iyo Paraganglioma waa in loo shakhsiyeeyaa qof kasta oo waa in sidoo kale la qabsado marka daaweynta kansarka ama isbeddelka hidda-socodka burooyinka. Shakhsiyaynta iyo la qabsiga waa in ay tixgelisaa dhammaan maaddooyinka firfircoon ama bioactives ee ku jira cuntooyinka kala duwan marka loo eego bayooloojiyada unugyada kansarka, genetics, daawaynta, xaaladaha qaab nololeedka iyo doorbidka cuntada. Sidaa darteed iyadoo nafaqadu ay tahay mid ka mid ah go'aamada aadka muhiimka u ah bukaanka kansarka iyo qofka halista ugu jira kansarka inuu sameeyo - sida loo doorto cuntooyinka uu cuno maaha hawl fudud.

Marka loo eego Pheochromocytoma iyo Paraganglioma muhiim ma u tahay waxa khudaarta, miraha, lawska, iniinta la cuno?

Su'aasha nafaqeynta ee aadka u badan ee ay weydiiyaan bukaannada kansarka iyo shakhsiyaadka halista ugu jira hidde-sidaha kansarka waa - kansarka sida Pheochromocytoma iyo Paraganglioma macno ma u leedahay cuntooyinka aan cuno iyo kuwa aanan samayn? Mise haddii aan raaco cunto ku salaysan geedka waa taas ku filan kansarka sida Pheochromocytoma iyo Paraganglioma?

Tusaale ahaan miyay muhiim tahay haddii khudradda Giant Butterbur la isticmaalo in ka badan marka loo eego Turnip? Miyay wax farqi ah samaynaysaa haddii miro oranji macaan laga doorbido Rabbiteye blueberry? Sidoo kale haddii xulashooyin la mid ah loo sameeyo nuts/abuurka sida Butternut oo ka sarreeya Macadamia Nut iyo garaacyada sida Gram Bean oo ka sarreeya Mung Bean. Oo haddii waxa aan cunaa ay arrintu khusayso - markaa sidee loo aqoonsan karaa cuntooyinka lagu taliyay Pheochromocytoma iyo Paraganglioma oo ma isku mid bay jawaab u tahay qof kasta oo leh isla cudurka ama khatarta hidde-sidaha?

Haa! Cuntooyinka aad cuntid waxay muhiim u yihiin Pheochromocytoma iyo Paraganglioma!

Talooyinka cuntadu waxay noqon karaan kuwo isku mid ah qof kasta oo way ka duwanaan karaan xitaa ogaanshaha isku midka ah iyo khatarta hidda-socodka.

Dhammaan cuntooyinka ( khudaarta, miraha, lawska, iniinaha, garaaca, saliidaha iwm.) iyo kaabayaasha nafaqadu waxay ka kooban yihiin wax ka badan hal walxo molecular ama bio-actives oo qiyaas iyo tiro kala duwan leh. Walax kasta oo firfircooni waxay leedahay hab u gaar ah oo wax qabad - kaas oo noqon kara firfircooni ama xannibaadda dariiqyada biochemical ee kala duwan. Cuntooyinka si fudud loo sheegay iyo kaabisyada lagu taliyay waa kuwa aan keenin korodhka wadayaasha molecular ee kansarka laakiin la yareeyo. Haddii kale cuntooyinkaas waa inaan lagu talin. Cuntooyinka waxaa ku jira maaddooyin badan oo firfircoon - markaa marka la qiimeynayo cuntooyinka iyo kaabayaasha waxaad u baahan tahay inaad tixgeliso saameynta dhammaan maaddooyinka firfircoon si wadajir ah halkii aad ka ahaan lahayd mid gaar ah.

Tusaale ahaan Orange macaan waxa ku jira maaddooyin firfircoon oo Luteolin, Phloretin, Bergapten, Cinnamaldehyde, Lupeol. Rabbiteye blueberry waxaa ku jira maaddooyin firfircoon oo ay ka mid yihiin Quercetin, Eugenol, Geraniol, Gallic Acid, Ferulic Acid iyo kuwo kale oo suurtogal ah.

Khalad caadi ah oo la sameeyo marka la go'aaminayo oo la dooranayo cuntooyinka loo cuno Pheochromocytoma iyo Paraganglioma - waa in la qiimeeyo oo kaliya maaddooyinka firfircoon ee la doortay ee ku jira cuntooyinka oo la iska indhatiro inta kale. Sababtoo ah maaddooyinka kala duwan ee firfircoon ee ku jira cuntooyinka ayaa laga yaabaa inay saameyn iska soo horjeeda ku yeeshaan darawalada kansarka - ma qaadan kartid maaddooyinka firfircoon ee cuntooyinka iyo kaabayaasha si loo gaaro go'aanka nafaqada ee Pheochromocytoma iyo Paraganglioma.

HAA – DOORASHOOYINKA CUNTADA EE KANSARKA WAXAY U TAAGAN YAHAY. GO'AANKA NAFAQADA waa in ay tixgeliyaan dhammaan walxaha firfircoon ee CUNTADA.

Xirfadaha Loo Baahan Yahay Nafaqaynta Shakhsiyaynta ee Pheochromocytoma iyo Paraganglioma?

Nafaqada shakhsi ahaaneed ee kansarrada sida Pheochromocytoma iyo Paraganglioma waxay ka kooban yihiin cuntooyin/kaabyo lagu taliyey; Cuntooyinka aan lagu talin/kabka tusaale ahaan cunto karinta kuwaas oo mudnaanta siiya isticmaalka cuntooyinka lagu taliyay. Tusaale nafaqeynta gaarka ah ayaa tan lagu arki karaa link.

Go'aaminta cuntooyinka lagu taliyay iyo kuwa aan lagu talin waa mid aad u adag, oo u baahan khibrad ku saabsan Pheochromocytoma iyo Paraganglioma biology, sayniska cuntada, genetics, biochemistry oo ay weheliso faham wanaagsan oo ku saabsan sida daawaynta kansarka u shaqeyso iyo baylahda la xidhiidha kuwaas oo daaweyntu ay joojin karto waxtarka.

Khibradda UGU YAR EE AQOONTA EE LOO BAAHAN YAHAY NAFAQADA SHAQSIYADEEDKA KANSARKA WAA: NOLOLIGA KANSARKA, CUNTADA CUNTADA, DAAWAYNTA KANSARKA IYO HIDDAHA HIDDAHA.

Astaamaha kansarka sida Pheochromocytoma iyo Paraganglioma

Dhammaan kansarrada sida Pheochromocytoma iyo Paraganglioma waxaa lagu tilmaami karaa nidaam gaar ah oo ah dariiqooyin kiimikaad - dariiqooyinka saxiixa ee Pheochromocytoma iyo Paraganglioma. Dariiqooyin kiimikaad sida dheef-shiid kiimikaad, Isbaarada wareegga unugyada, Gaadiidka Molecule-yar, Beddelka Turjumaada kadib waa qayb ka mid ah qeexida saxiixa ee Pheochromocytoma iyo Paraganglioma. Hidde-sideyaasha kansarku qof walba wuu ka duwanaan karaa sidaas darteed saxiixooda gaarka ah ee kansarku wuxuu noqon karaa mid gaar ah.

Daawaynta waxtarka u leh Pheochromocytoma iyo Paraganglioma waxay u baahan yihiin inay ogaadaan dariiqooyinka biochemical ee la xidhiidha saxeexa bukaan kasta oo kansar ah iyo qof kasta oo khatarta hidde-sidaha. Sidaa darteed daawayn kala duwan oo leh habab kala duwan oo ficil ah ayaa waxtar u leh bukaanada kala duwan. Si la mid ah iyo sababo la mid ah cuntooyinka iyo kaabista waxay u baahan yihiin in shaqsi kasta loo gaaryeelo. Sidaa darteed cuntooyinka iyo kaabista qaar ayaa lagula talinayaa Pheochromocytoma iyo Paraganglioma marka la qaadanayo daawaynta kansarka Cyclophosphamide, iyo cuntooyinka iyo kaabista qaar laguma talinayo.

Ilaha sida cBioPortal iyo qaar kale oo badan ayaa bixiya xogta bukaan-socodka ee aan la magacaabin ee laga helay tijaabooyinka bukaan-socodka ee dhammaan calaamadaha kansarka. Xogtan waxay ka kooban tahay tafaasiisha daraasadda tijaabada caafimaad sida cabbirka saamiga / tirada bukaannada, kooxaha da'da, jinsiga, qowmiyadda, daawaynta, goobta burooyinka iyo isbeddellada hidde-sidaha.

EPAS1, AWAT1, POLR1A, ATRX iyo ACER2 waa hiddo-wadaha ugu sarreeya ee la soo sheegay ee Pheochromocytoma iyo Paraganglioma. EPAS1 ayaa lagu soo warramey 6.5 % bukaanada matala dhamaan tijaabooyinka kiliinikada. AWAT1 ayaa lagu soo warramey 3.2 %. Isku darka xogta bukaan-socodka ee dadweynaha ayaa daboolaya da'da 19 ilaa 83. 45.0 % xogta bukaanka waxaa loo aqoonsaday inay yihiin rag. Pheochromocytoma iyo Paraganglioma biology oo ay weheliso hidde-sideyaasha la soo sheegay ayaa si wada jir ah u qeexaya dariiqooyinka biochemical ee saxeexa dadweynaha ee kansarkan. Haddii genetics-ka burada kansarka shakhsi ahaaneed ama hiddo-wadaha ka qaybqaata khatarta sidoo kale waa la yaqaan markaa waa in sidoo kale loo isticmaalo shakhsiyaynta nafaqada.

Dookhyada nafaqeynta waa in ay iswaafaqaan shaqsi walba saxiixiisa.

Cuntada iyo Kaabayaasha loogu talagalay Pheochromocytoma iyo Paraganglioma

Bukaanka Kansarka

Bukaanjiifka kansarka ee ku jira daawaynta ama daryeelka palliative waxay u baahan yihiin inay go'aan ka gaadhaan cuntada iyo kaabista - kaloriinta cuntada ee loo baahan yahay, maaraynta waxyeellooyin kasta oo daawaynta iyo sidoo kale hagaajinta maaraynta kansarka. Dhammaan cuntooyinka dhirta ku salaysan maaha kuwo siman oo doorashada iyo kala horraysiinta cuntooyinka kuwaas oo shakhsi ahaan loo habeeyey oo loo habeeyey daawaynta kansarka ee socota waa muhiim oo dhib badan. Waa kuwan tusaalayaal siinaya tilmaamo lagu samaynayo go'aannada nafaqada.

Dooro Qudaar GIANT BUTTERBUR ama rogman?

Khudaarta Giant Butterbur waxay ka kooban tahay waxyaabo badan oo firfircoon ama bioactives sida Apigenin, Luteolin, Myricetin, Phloretin, Cinnamaldehyde. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida wareegga unugyada, Epithelial ilaa Mesenchymal Transition, Dheef-shiid kiimikaad iyo Calaamadaynta MAPK iyo kuwa kale. Giant Butterbur waxaa lagula talinayaa Pheochromocytoma iyo Paraganglioma marka daawaynta kansarka ee socota ay tahay Cyclophosphamide. Tani waa sababta oo ah Giant Butterbur waxay wax ka beddeshaa dariiqyada biochemical ee si cilmiyeysan loo soo sheegay si loo dareemo saameynta Cyclophosphamide.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee ku jira Turnip khudradda waa Quercetin, Ellagic Acid, Phloretin, Cinnamaldehyde, Bergapten. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida Dayactirka DNA-da iyo Epithelial ilaa Mesenchymal Transition iyo kuwa kale. Turnip laguma talinayo Pheochromocytoma iyo Paraganglioma marka daawaynta kansarka ee socota ay tahay Cyclophosphamide sababtoo ah waxay wax ka beddeshaa dariiqyada biochemical ee ka dhigaya daawaynta kansarka mid adkaysi u leh ama aan ka jawaabin.

BUTTERBUR WEYN ayaa lagula talinayaa in la beddelo Pheochromocytoma iyo Paraganglioma iyo daawaynta Cyclophosphamide.

Dooro miro RABBITEY bulukeeti ama oranji macaan?

Miraha Rabbiteye Blueberry waxaa ku jira waxyaabo badan oo firfircoon ama bioactives sida Quercetin, Eugenol, Geraniol, Gallic Acid, Ferulic Acid. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida Dayactirka DNA-da, Wareegga Unugyada, Calaamadaynta MAPK iyo Isbaarooyinka Wareegga Unugyada iyo kuwa kale. Rabbiteye blueberry waxaa lagula talinayaa Pheochromocytoma iyo Paraganglioma marka daawaynta kansarka ee socota ay tahay Cyclophosphamide. Tani waa sababta oo ah Rabbiteye Blueberry waxay wax ka beddeshaa dariiqyada biochemical ee si cilmiyeysan loo soo sheegay si loo dareemo saameynta Cyclophosphamide.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee ku jira miro Orange macaan waa Luteolin, Phloretin, Bergapten, Cinnamaldehyde, Lupeol. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida Dayactirka DNA-ga iyo Isbaarooyinka Wareegga Unugyada iyo kuwa kale. Liin macaan laguma talinayo Pheochromocytoma Iyo Paraganglioma marka daawaynta kansarka ee socota ay tahay Cyclophosphamide sababtoo ah waxay wax ka beddeshaa dariiqyada biochemical ee ka dhigaya daawaynta kansarka mid adkaysi u leh ama aan ka jawaabin.

FRUIT RABBITEY BLUEBERRY AYAA LAGULA TALAGANAYAA liimi macaan oo loogu talagalay Pheochromocytoma iyo Paraganglioma iyo daawaynta Cyclophosphamide.

Dooro lowska BUTTERNUT ama MACADAMIA NUT?

Butternut wuxuu ka kooban yahay waxyaabo badan oo firfircoon ama bioactives sida Apigenin, Luteolin, Myricetin, Phloretin, Cinnamaldehyde. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida wareegga unugyada, dheef-shiid kiimikaadka Vitamin, Dayactirka DNA-ga iyo Epithelial ilaa Mesenchymal Transition iyo kuwa kale. Butternut ayaa lagula talinayaa Pheochromocytoma iyo Paraganglioma marka daaweynta kansarka ee socota waa Cyclophosphamide. Tani waa sababta oo ah Butternut waxay wax ka beddeshaa dariiqyada biochemical ee si cilmiyeysan loo soo sheegay si loo dareemo saameynta Cyclophosphamide.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee Macadamia Nut waa Apigenin, Luteolin, Myricetin, Phloretin, Cinnamaldehyde. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida MAPK Signaling iyo kuwa kale. Macadamia nuts laguma talinayo Pheochromocytoma iyo Paraganglioma marka daawaynta kansarka ee socota ay tahay Cyclophosphamide sababtoo ah waxay wax ka beddeshaa dariiqyada biochemical ee ka dhigaya daaweynta kansarka mid adkaysi u leh ama aan ka jawaabin.

BUTTERNUT ayaa lagula talinayaa in loo isticmaalo looska MACADAMIA loogu talagalay Pheochromocytoma iyo Paraganglioma iyo daawaynta Cyclophosphamide.

Shakhsiyaadka leh Khatarta Hidde ee Kansarka

Su'aasha ay weydiiyaan shakhsiyaadka leh khatarta hidde-sidaha ee Pheochromocytoma iyo Paraganglioma ama taariikhda qoysku waa "Maxaan Cunnaa si ka duwan kii hore?" iyo sida ay tahay inay doortaan cuntooyinka iyo kaabista si loo maareeyo khatarta cudurka. Maadaama khatarta kansarku aanay jirin wax la qaban karo marka la eego daawaynta - go'aamada cuntooyinka iyo kaabista ayaa noqda mid muhiim ah iyo mid ka mid ah waxyaallaha aadka u yar ee la qaban karo. Dhammaan cuntooyinka dhirta ku salaysan maaha kuwo siman oo ku salaysan hidde-sidaha la aqoonsaday iyo saxeexa dariiqa - doorashooyinka cuntada iyo kaabista waa in la shakhsiyeeyo.

Dooro GARDEN CRESS ama LATTUCE ROMAINE?

Beerta khudaarta waxaa ku jira waxyaabo badan oo firfircoon ama bioactives ah sida Curcumin, Lupeol, Beta-sitosterol, Formononetin, Vitamin C. Maaddooyinkan firfircooni waxay wax ka qabtaan dariiqooyin kiimiko oo kala duwan sida TGFB Signaling, P53 Signaling, Checkpoints Cycle Cell and MYC Signaling iyo kuwa kale. Beerta Cress waxa lagula talinayaa khatarta Pheochromocytoma iyo Paraganglioma marka khatarta hidde-sidaha la xidhiidha ACER2. Tani waa sababta oo ah Beerta Cress waxay kordhisaa dariiqyada biochemical ee ka soo horjeeda wadayaasha saxeexa.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee khudradda Romaine Lettuce waa Curcumin, Apigenin, Lupeol, Resveratrol, Formononetin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida Lipid Metabolism iyo P53 Signaling iyo kuwa kale. Romaine Lettuce laguma talinayo marka halista Pheochromocytoma iyo Paraganglioma marka khatarta hidde-sidaha lala xiriiriyo ACER2 sababtoo ah waxay kordhisaa dariiqyada saxiixa.

Beerta khudaarta leh waxaa lagula talinayaa warqada ROMAINE ee loogu talagalay khatarta hidda-socodka ACER2 ee kansarka.

Dooro Miraha Crowberry MADOW ama GRAPEFRUIT?

Miraha Black Crowberry waxaa ku jira waxyaabo badan oo firfircoon ama bioactives sida Curcumin, Apigenin, Quercetin, Lupeol, Lycopene. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida TGFB Signaling, Hypoxia, Signaling P53 iyo Turjumaadda Dib-u-habaynta iyo kuwa kale. Crowberry Black waxaa lagula talinayaa khatarta Pheochromocytoma iyo Paraganglioma marka khatarta hidde-sidaha la xiriirta ACER2. Tani waa sababta oo ah Crowberry Black waxay kordhisaa dariiqyada biochemical ee ka soo horjeeda wadayaasha saxiixa.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee ku jira canabka miraha waa Curcumin, Lupeol, Lycopene, Formononetin, Beta-sitosterol. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida TGFB Signaling iyo Lipid Metabolism iyo kuwa kale. Canabka laguma talinayo marka khatarta ah Pheochromocytoma iyo Paraganglioma marka khatarta hidde-sidaha lala xiriiriyo ACER2 sababtoo ah waxay kordhisaa dariiqyada saxiixa.

Miraha Crowberry-madow waxaa lagula taliyaa canab-barka oo loogu talagalay khatarta hidda-socodka ee ACER2.

Dooro lowska CHIA ama HICKORY NUT?

Chia waxaa ku jira waxyaabo badan oo firfircoon ama bioactives sida Curcumin, Apigenin, Lupeol, Lycopene, Formononetin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida TGFB Signaling, Hypoxia, P53 Signaling iyo MYC Signaling iyo kuwa kale. Chia waxaa lagula talinayaa khatarta Pheochromocytoma iyo Paraganglioma marka khatarta hidde-sidaha la xiriirta ay tahay ACER2. Tani waa sababta oo ah Chia waxay kordhisaa dariiqooyinka biochemical ee ka soo horjeeda wadayaasha saxeexa.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee Hickory Nut waa Curcumin, Apigenin, Lupeol, Lycopene, Formononetin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida Dheef-shiid kiimikaad iyo Isbaarada wareegga unugyada iyo kuwa kale. Hickory Nut laguma talinayo marka halista Pheochromocytoma iyo Paraganglioma marka khatarta hidde-sidaha lala xiriiriyo ay tahay ACER2 sababtoo ah waxay kordhisaa dariiqyada saxiixa.

CHIA waxaa lagula talinayaa HICKORY NUT ee khatarta hidda-socodka ACER2 ee kansarka.

In Gabagabo

Cuntooyinka iyo Kaabayaasha la doortay waa go'aamo muhiim u ah kansarka sida Pheochromocytoma iyo Paraganglioma. Bukaannada Pheochromocytoma iyo Paraganglioma iyo shakhsiyaadka leh khatarta hidde-sidaha waxay had iyo jeer qabaan su'aashan: "Waa maxay cuntooyinka iyo nafaqooyinka nafaqada ee lagu taliyay aniga iyo kuwa aan ahayn?" Waxaa jira aaminsanaan guud oo ah fikrad khaldan oo ah in dhammaan cuntooyinka dhirta ku salaysan ay faa'iido yeelan karaan ama aysan ahayn laakiin aan waxyeello lahayn. Cuntooyinka qaarkood iyo kaabisyada qaarkood waxay faragelin karaan daawaynta kansarka ama waxay kor u qaadi karaan wadayaasha dariiqyada molecular ee kansarka.

Waxaa jira noocyo kala duwan oo tilmaamayaasha kansarka sida Pheochromocytoma iyo Paraganglioma, mid kasta oo leh hidde-sidaha burooyinka oo kala duwan oo leh kala duwanaansho genomic oo dheeraad ah oo qof kasta ah. Intaa waxaa dheer daawaynta kansar kasta iyo kiimoterabi kasta waxay leeyihiin hab wax-qabad oo gaar ah. Cunto kasta sida Giant Butterbur waxay ka kooban tahay noocyo kala duwan oo bioactives ah oo tirooyin kala duwan leh, kuwaas oo saameyn ku leh noocyo kala duwan oo kala duwan oo ah dariiqyada biochemical. Qeexida nafaqeynta shakhsi ahaaneed waa talooyinka cuntada ee gaarka ah ee tilmaamaya kansarka, daawaynta, genetics, qaab nololeedka iyo arrimo kale. Go'aannada shakhsiyaynta nafaqada ee kansarka waxay u baahan yihiin aqoonta bayoolajiga kansarka, sayniska cuntada iyo fahamka daaweynta kemotherabi ee kala duwan. Ugu dambeyntii marka ay jiraan isbeddel daaweyn ama genomics cusub ayaa la aqoonsaday - shakhsiyeynta nafaqeynta waxay u baahan tahay dib-u-qiimeyn.

Xalka shakhsiyaynta nafaqeynta ee addon ayaa ka dhigaysa go'aan qaadashada mid fudud oo meesha ka saaraysa dhammaan mala-awaalka ka jawaabaya su'aasha, "Cunto noocee ah ayaan dooran karaa ama ma dooran karaa Pheochromocytoma iyo Paraganglioma?". Kooxda edbinta badan ee addon waxaa ka mid ah dhakhaatiirta kansarka, saynisyahano caafimaad, injineerada software iyo saynisyahano xogta.

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