Cuntooyinka loogu talagalay Myelodysplastic Syndrome!

Hordhac

Cuntooyinka loogu talagalay xanuunka 'Myelodysplastic Syndrome' waa in loo shakhsiyeeyo qof kasta oo waa in sidoo kale la qabsado marka daaweynta kansarka ama hidda-socodka buradu ay isbeddelaan. Shakhsiyaynta iyo la qabsiga waa in ay tixgelisaa dhammaan maaddooyinka firfircoon ama bioactives ee ku jira cuntooyinka kala duwan marka loo eego bayooloojiyada unugyada kansarka, genetics, daawaynta, xaaladaha qaab nololeedka iyo doorbidka cuntada. Sidaa darteed iyadoo nafaqadu ay tahay mid ka mid ah go'aamada aadka muhiimka u ah bukaanka kansarka iyo qofka halista ugu jira kansarka inuu sameeyo - sida loo doorto cuntooyinka uu cuno maaha hawl fudud.

Myelodysplastic syndromes (MDS) waa koox kansar dhiig ah oo saameeya soo saarista unugyada dhiigga ee caadiga ah ee dhuuxa lafta. Marka unugyada leukemia ee aan caadiga ahayn kala qaybsamaan, isbeddelka asalka ah waa la ilaaliyaa wuxuuna soo saaraa unug unugyo aan caadi ahayn oo isku mid ah oo isku mid ah oo leh cillad isku mid ah, markaa MDS waa cillad unugyada unugyada dhiigga ee clonal. Cudurka 'Myelodysplastic syndromes' wuxuu ku badan yahay dadka da'da ah ee ka weyn 60 sano waxayna saameeyaan ragga wax yar in ka badan dumarka. MDS, unugyada tarma ee dhuuxa lafta aan caadiga ahayn (sidoo kale loo yaqaan qaraxyada) waxay soo saaraan tiro badan oo unugyo dhiig ah oo aan qaan-gaarin kuwaas oo inta badan u dhinta xilli hore. Tani waxay keenaysaa in tiro yar oo ah unugyada dhiigga cas ee bislaaday, unugyada dhiigga cad iyo platelets taasoo ka dhigaysa bukaanka mid aad ugu nugul caabuqyada, dhiig-baxa, nabarrada iyo daalka. MDS waxaa loo kala saaraa iyadoo loo eegayo nooca iyo tirada qaraxyada ee dhuuxa lafta 5 nooc oo hoose: dhiig-yarida refractory; anemia refractory oo leh sideroblasts; anemia refractory oo leh qaraxyo xad dhaaf ah; anemia refractory oo leh qaraxyo xad-dhaaf ah oo isbeddel ah; iyo leukemia myelomonocytic chronic (CMML). Dadka qaba MDS waxay leeyihiin dhuuxa lafo firfircoon laakiin tirada unugyada dhiigga aan caadi ahayn ayaa hooseeya. Calaamadaha guud ee la xidhiidha MDS waxaa ka mid ah daal, dawakhaad, daciifnimo, nabar iyo dhiig-bax, caabuqyo soo noqnoqda, iyo madax-xanuun. Xaaladaha qaarkood, MDS waxa laga yaabaa inay u gudubto guuldarada nafta halis gelisa ee dhuuxa lafta ama waxay isu bedeshaa acute myeloid leukemia (AML). Ikhtiyaarada daawaynta ee xanuunka 'myelodysplastic syndromes' waxaa ka mid ah dhiig ku shubista, arrimaha koritaanka sida granulocyte-colony stymululation factor (G-CSF), wakiilada hypomethylating, wakiilada immunomodulatory, iyo kiimoterabi. Intaa waxaa dheer, daryeelka taageerada leh nafaqeynta saxda ah (cuntooyinka iyo kaabayaasha dabiiciga ah) waxay gacan ka geysan karaan hagaajinta fayoobaanta bukaanka.

Myelodysplastic Syndrome miyay muhiim u tahay khudaarta, miraha, lawska, miraha la cuno?

Su'aasha nafaqeynta ee aadka caanka ah ee ay weydiiyaan bukaannada kansarka iyo shakhsiyaadka halista ugu jira hidde-sidaha kansarka waa - kansarka sida Myelodysplastic Syndrome miyay muhiim tahay cuntooyinka aan cuno iyo kuwa aanan samayn? Mise haddii aan raaco cunto ku salaysan dhirta waa intaas in ku filan kansarka sida Myelodysplastic Syndrome?

Tusaale ahaan miyay muhiim tahay haddii Khudaarta Dhuxulka la isticmaalo in ka badan marka loo eego Kaabashka Cad? Miyay wax farqi ah samaynaysaa haddii khudaarta Pummelo laga doorbido Raspberry Cas? Sidoo kale haddii xulashooyin la mid ah loo sameeyo nuts/abuurka sida Hazelnut oo ka sarreeya Chestnut Yurub iyo garaacyada sida Adzuki Bean oo ka sarreeya digirta cagaaran. Oo haddii waxa aan cuno ay arrintu khusayso - markaa sidee qofku u aqoonsan karaa cuntooyinka lagu taliyey Myelodysplastic Syndrome oo ma isku mid bay u tahay qof kasta oo leh isla cudurka ama khatarta hidde-sidaha?

Haa! Cuntooyinka aad cuntid ayaa arrimaha u ah Myelodysplastic Syndrome!

Talooyinka cuntadu waxay noqon karaan kuwo isku mid ah qof kasta oo way ka duwanaan karaan xitaa ogaanshaha isku midka ah iyo khatarta hidda-socodka.

Dhammaan cuntooyinka ( khudaarta, miraha, lawska, iniinaha, garaaca, saliidaha iwm.) iyo kaabayaasha nafaqadu waxay ka kooban yihiin wax ka badan hal walxo molecular ama bio-actives oo qiyaas iyo tiro kala duwan leh. Walax kasta oo firfircooni waxay leedahay hab u gaar ah oo wax qabad - kaas oo noqon kara firfircooni ama xannibaadda dariiqyada biochemical ee kala duwan. Cuntooyinka si fudud loo sheegay iyo kaabisyada lagu taliyay waa kuwa aan keenin korodhka wadayaasha molecular ee kansarka laakiin la yareeyo. Haddii kale cuntooyinkaas waa inaan lagu talin. Cuntooyinka waxaa ku jira maaddooyin badan oo firfircoon - markaa marka la qiimeynayo cuntooyinka iyo kaabayaasha waxaad u baahan tahay inaad tixgeliso saameynta dhammaan maaddooyinka firfircoon si wadajir ah halkii aad ka ahaan lahayd mid gaar ah.

Tusaale ahaan Pummelo waxa ku jira maaddooyinka firfircoon ee Apigenin, Curcumin, Quercetin, Isoliquiritigenin, Lupeol. Raspberry-ka cas waxaa ku jira maaddooyin firfircoon Curcumin, Quercetin, Isoliquiritigenin, Ellagic Acid, Lupeol iyo kuwo kale oo suurtagal ah.

Khalad caadi ah oo la sameeyo marka la go'aaminayo oo la dooranayo cuntooyinka la cuno ee Myelodysplastic Syndrome - waa in la qiimeeyo oo kaliya maaddooyinka firfircoon ee la doortay ee ku jira cuntooyinka oo la iska indhatiro inta kale. Sababtoo ah maaddooyinka kala duwan ee firfircoon ee ku jira cuntooyinka ayaa laga yaabaa inay saameyn iska soo horjeeda ku yeeshaan darawalada kansarka - ma qaadan kartid maaddooyinka firfircoon ee cuntooyinka iyo kaabayaasha si loo gaaro go'aanka nafaqada ee Myelodysplastic Syndrome.

HAA – DOORASHOOYINKA CUNTADA EE KANSARKA WAXAY U TAAGAN YAHAY. GO'AANKA NAFAQADA waa in ay tixgeliyaan dhammaan walxaha firfircoon ee CUNTADA.

Xirfadaha Loo Baahan Yahay Nafaqaynta Shakhsiyaynta ee Cudurka Myelodysplastic Syndrome?

Nafaqada shakhsi ahaaneed ee kansarrada sida Myelodysplastic Syndrome waxay ka kooban tahay cuntooyin/kaabyo lagu taliyey; Cuntooyinka aan lagu talin/kabka tusaale ahaan cunto karinta kuwaas oo mudnaanta siiya isticmaalka cuntooyinka lagu taliyay. Tusaale nafaqeynta gaarka ah ayaa tan lagu arki karaa link.

Go'aaminta cuntooyinka lagu taliyay iyo in kale waa mid aad u adag, oo u baahan khibrad ku saabsan bayoolajiga Myelodysplastic Syndrome, sayniska cuntada, genetics, biochemistry oo ay weheliso faham wanaagsan oo ku saabsan sida daawaynta kansarku u shaqeyso iyo baylahda la xidhiidha kuwaas oo daaweyntu ay joojin karto waxtarka.

Khibradda UGU YAR EE AQOONTA EE LOO BAAHAN YAHAY NAFAQADA SHAQSIYADEEDKA KANSARKA WAA: NOLOLIGA KANSARKA, CUNTADA CUNTADA, DAAWAYNTA KANSARKA IYO HIDDAHA HIDDAHA.

Astaamaha kansarka sida Myelodysplastic Syndrome

Dhammaan kansarrada sida Myelodysplastic Syndrome waxaa lagu gartaa qayb gaar ah oo ka mid ah dariiqooyinka biochemical - waddooyinka saxiixa ee Myelodysplastic Syndrome. Dariiqooyinka biochemical sida dheef-shiid kiimikaad Amino Acid, Histone/Protein Acetylation, RUNX Signaling, RAS-RAF Signaling waa qayb ka mid ah qeexida saxeexa ee Myelodysplastic Syndrome. Hidde-sideyaasha kansarku qof walba wuu ka duwanaan karaa sidaas darteed saxiixooda gaarka ah ee kansarku wuxuu noqon karaa mid gaar ah.

Daawaynta waxtarka u leh cudurka 'Myelodysplastic Syndrome' waxay u baahan yihiin inay ogaadaan dariiqyada biochemical ee la xidhiidha saxeexa bukaan kasta oo kansar ah iyo shakhsi ahaan khatarta hidde-sidaha. Sidaa darteed daawayn kala duwan oo leh habab kala duwan oo ficil ah ayaa waxtar u leh bukaanada kala duwan. Si la mid ah iyo sababo la mid ah cuntooyinka iyo kaabista waxay u baahan yihiin in shaqsi kasta loo habeeyo. Markaa cuntooyinka iyo kaabista qaar ayaa lagula taliyaa Myelodysplastic Syndrome marka la qaadanayo daawaynta kansarka Lenalidomide, iyo cuntooyinka qaar iyo kaabista laguma talinayo.

Ilaha sida cBioPortal iyo qaar kale oo badan ayaa bixiya xogta bukaan-socodka ee aan la magacaabin ee laga helay tijaabooyinka bukaan-socodka ee dhammaan calaamadaha kansarka. Xogtan waxay ka kooban tahay tafaasiisha daraasadda tijaabada caafimaad sida cabbirka saamiga / tirada bukaannada, kooxaha da'da, jinsiga, qowmiyadda, daawaynta, goobta burooyinka iyo isbeddellada hidde-sidaha.

RUNX1, NSD1, JAK2, KMT2A iyo EP300 waa hiddo-wadaha ugu sarreeya ee la soo sheegay ee cudurka Myelodysplastic Syndrome. RUNX1 ayaa lagu soo warramey 16.1 % bukaanada mataleysa dhamaan tijaabooyinka caafimaad. Iyo NSD1 ayaa lagu soo warramey 6.7 %. Isku darka xogta bukaan-socodka ee dadweynaha waxay daboolaysaa da'da 24 ilaa 86. 58.6 % xogta bukaan-socodka waxaa loo aqoonsaday inay yihiin rag. Bayoolojiga Myelodysplastic Syndrome oo ay weheliso hidde-sideyaasha la soo sheegay ayaa si wada jir ah u qeexaya dariiqooyinka biochemical ee saxeexa dadweynaha ee kansarkan. Haddii genetics-ka burada kansarka shakhsi ahaaneed ama hiddo-wadaha ka qaybqaata khatarta sidoo kale waa la yaqaan markaa waa in sidoo kale loo isticmaalo shakhsiyaynta nafaqada.

Dookhyada nafaqeynta waa in ay iswaafaqaan shaqsi walba saxiixiisa.

Cuntada iyo Kaabayaasha loogu talagalay Cudurka Myelodysplastic Syndrome

Bukaanka Kansarka

Bukaanjiifka kansarka ee ku jira daawaynta ama daryeelka palliative waxay u baahan yihiin inay go'aan ka gaadhaan cuntada iyo kaabista - kaloriinta cuntada ee loo baahan yahay, maaraynta waxyeellooyin kasta oo daawaynta iyo sidoo kale hagaajinta maaraynta kansarka. Dhammaan cuntooyinka dhirta ku salaysan maaha kuwo siman oo doorashada iyo kala horraysiinta cuntooyinka kuwaas oo shakhsi ahaan loo habeeyey oo loo habeeyey daawaynta kansarka ee socota waa muhiim oo dhib badan. Waa kuwan tusaalayaal siinaya tilmaamo lagu samaynayo go'aannada nafaqada.

Dooro khudaar wax GOURD ah ama kaabash CAD?

Gourd-ka khudradda waxaa ku jira waxyaabo badan oo firfircoon ama bioactives sida Apigenin, Curcumin, Isoliquiritigenin, Luteolin, Lupeol. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida wareegga unugyada, Hypoxia, P53 Signaling iyo MYC Signaling iyo kuwa kale. Wax Gourd ayaa lagula talinayaa Myelodysplastic Syndrome marka daawaynta kansarka ee socota ay tahay Lenalidomide. Tani waa sababta oo ah Wax Gourd waxay wax ka beddeshaa dariiqyada biochemical ee si cilmiyeysan loo soo sheegay si loo dareemo saameynta Lenalidomide.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee khudradda cad ee Kaabashka waa Curcumin, Quercetin, Isoliquiritigenin, Lupeol, Kaempferol. Maaddooyinkan firfircooni waxay wax ka qabtaan dariiqooyin kiimikaad oo kala duwan sida Cadaadiska Oxidative iyo kuwa kale. Kaabashka cad laguma talinayo Myelodysplastic Syndrome marka daawaynta kansarka ee socota ay tahay Lenalidomide sababtoo ah waxay wax ka beddeshaa dariiqyada biochemical ee ka dhigaya daaweynta kansarku mid adkaysi u leh ama aan ka jawaabin.

GOURDKA QARDOONKA ayaa lagula taliyaa kaabajka cadcad ee loogu talagalay xanuunka Myelodysplastic Syndrome iyo daawaynta Lenalidomide.

Dooro midhaha raspberry cas ama PUMMELO?

Khudradu waxay ka kooban tahay waxyaabo badan oo firfircoon ama bioactives sida Curcumin, Quercetin, Isoliquiritigenin, Ellagic Acid, Lupeol. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida wareegga unugyada, Hypoxia, P53 Signaling iyo MYC Signaling iyo kuwa kale. Raspberry cas ayaa lagula talinayaa Myelodysplastic Syndrome marka daawaynta kansarka ee socota ay tahay Lenalidomide. Tani waa sababta oo ah Raspberry Cas ayaa wax ka beddelaya dariiqyada biochemical ee si cilmiyeysan loo soo sheegay si loo dareemo saameynta Lenalidomide.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee ku jira miro Pummelo waa Apigenin, Curcumin, Quercetin, Isoliquiritigenin, Lupeol. Maaddooyinkan firfircooni waxay wax ka qabtaan dariiqooyin kiimikaad oo kala duwan sida Cadaadiska Oxidative iyo kuwa kale. Pummelo laguma talinayo Myelodysplastic Syndrome marka daawaynta kansarka ee socota ay tahay Lenalidomide sababtoo ah waxay wax ka beddeshaa dariiqyada biochemical ee ka dhigaya daaweynta kansarku mid adkaysi u leh ama ka jawaabi kara.

Raspberry cas ee miraha waxaa lagula talinayaa PUMMELO oo loogu talagalay xanuunka Myelodysplastic Syndrome iyo daawaynta Lenalidomide.

Dooro Nut HAZELNUT ama XARUNTA YURUB?

Hazelnut wuxuu ka kooban yahay waxyaabo badan oo firfircoon ama bioactives sida Apigenin, Curcumin, Isoliquiritigenin, Luteolin, Lupeol. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida wareegga unugyada, Histone/Protein Acetylation, P53 Signaling iyo Hypoxia iyo kuwa kale. Hazelnut waxaa lagula talinayaa Myelodysplastic Syndrome marka daawaynta kansarka ee socota ay tahay Lenalidomide. Tani waa sababta oo ah Hazelnut waxay wax ka beddeshaa dariiqyada biochemical ee si cilmiyeysan loo soo sheegay si loo dareemo saameynta Lenalidomide.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee Chestnut Yurub waa Apigenin, Curcumin, Quercetin, Isoliquiritigenin, Ellagic Acid. Maaddooyinkan firfircooni waxay wax ka qabtaan dariiqooyin kiimikaad oo kala duwan sida Cadaadiska Oxidative iyo kuwa kale. Chestnut Yurub laguma talinayo Myelodysplastic Syndrome marka daawaynta kansarka ee socota ay tahay Lenalidomide sababtoo ah waxay wax ka beddeshaa dariiqyada biochemical ee ka dhigaya daaweynta kansarku mid adkaysi u leh ama ka jawaabi kara.

HAZELNUT waxaa lagula talinayaa laabta Yurub ee loogu talagalay xanuunka Myelodysplastic Syndrome iyo daawaynta Lenalidomide.

Shakhsiyaadka leh Khatarta Hidde ee Kansarka

Su'aasha ay weydiiyaan shakhsiyaadka leh khatarta hidde-sidaha ee Myelodysplastic Syndrome ama taariikhda qoysku waa "Maxaan Cunnaa si ka duwan kii hore?" iyo sida ay tahay inay doortaan cuntooyinka iyo kaabista si loo maareeyo khatarta cudurka. Maadaama khatarta kansarku aanay jirin wax la qaban karo marka la eego daawaynta - go'aamada cuntooyinka iyo kaabista ayaa noqda mid muhiim ah iyo mid ka mid ah waxyaallaha aadka u yar ee la qaban karo. Dhammaan cuntooyinka dhirta ku salaysan maaha kuwo siman oo ku salaysan hidde-sidaha la aqoonsaday iyo saxeexa dariiqa - doorashooyinka cuntada iyo kaabista waa in la shakhsiyeeyo.

Dooro ZUCCHINI JALE ah khudaar ama SWEDE?

Zucchini jaalaha ah khudradda waxaa ku jira waxyaabo badan oo firfircoon ama bioactives sida Curcumin, Apigenin, Formononetin, Lupeol, Phloretin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida TGFB Signaling, Histone/Protein Acetylation, Isbaarada Wareegga Unugyada iyo Calaamadaynta MYC iyo kuwa kale. Zucchini jaalaha ah ayaa lagula talinayaa khatarta Myelodysplastic Syndrome marka khatarta hidde-raaca ee la xiriirta ay tahay EP300. Tani waa sababta oo ah Zucchini jaalaha ah waxay kordhisaa dariiqyada biochemical ee ka soo horjeeda wadayaasha saxiixa.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee khudradda Iswiidhishka waa Curcumin, Apigenin, Formononetin, Lupeol, Phloretin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida TGFB Signaling iyo kuwa kale. Iswiidhishka laguma talinayo marka halista Myelodysplastic Syndrome marka khatarta hidda-socodka ee la xiriirta ay tahay EP300 sababtoo ah waxay kordhisaa dariiqyada saxiixa.

ZUCCHINI JAALE KHUDUR AH AYAA GUUD SWED lagula talinayaa EP300 Khatarta Hidde ee Kansarka.

Dooro khudaar cherry ama JUJUBE?

Khudradu waxay ka kooban tahay waxyaabo badan oo firfircoon ama bioactives sida Curcumin, Apigenin, Formononetin, Lupeol, Phloretin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimiko oo kala duwan sida TGFB Signaling, Histone/Protein Acetylation, PI3K-AKT-MTOR Signaling iyo MYC Signaling iyo kuwa kale. Cherry dhanaan ayaa lagula talinayaa halista Myelodysplastic Syndrome marka khatarta hidde-raaca la xiriirta ay tahay EP300. Tani waa sababta oo ah Cherry dhanaanku waxay kordhisaa dariiqyada biochemical ee ka soo horjeeda wadayaasha saxeexa.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee ku jira Jujube miro waa Curcumin, Apigenin, Formononetin, Lupeol, Phloretin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida TGFB Signaling, PI3K-AKT-MTOR Signaling iyo Isbaarooyinka Wareegga Gacanta iyo kuwa kale. Jujube laguma talinayo marka halista Myelodysplastic Syndrome marka khatarta hidde-sidaha la xiriirta ay tahay EP300 sababtoo ah waxay kordhisaa dariiqyada saxiixa.

cherry dhanaan miraha waxaa lagula talinayaa JUJUBE EP300 khatarta hidda-socodka ee kansarka.

Dooro lowska BUTTERNUT ama CHESTNUT?

Butternut wuxuu ka kooban yahay waxyaabo badan oo firfircoon ama bioactives sida Curcumin, Apigenin, Formononetin, Lupeol, Phloretin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida TGFB Signaling, Histone/Protein Acetylation, Isbaarada Wareegga Unugyada iyo Calaamadaynta MYC iyo kuwa kale. Butternut ayaa lagula talinayaa khatarta Myelodysplastic Syndrome marka khatarta hidde-raaca ee la xiriirta ay tahay EP300. Tani waa sababta oo ah Butternut waxay kordhisaa dariiqyada biochemical ee ka soo horjeeda wadayaasha saxiixa.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee ku jira Chestnut waa Curcumin, Apigenin, Formononetin, Lupeol, Phloretin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida TGFB Signaling iyo Koontaroolada wareegga unugyada iyo kuwa kale. Chestnut laguma talinayo marka halista Myelodysplastic Syndrome marka khatarta hidda-socodka la xiriirta ay tahay EP300 sababtoo ah waxay kordhisaa dariiqyada saxiixa.

BUTTERNUT waxa lagula taliyaa laabta si loo helo halista hidda-socodka ee EP300.

In Gabagabo

Cuntooyinka iyo Kaabayaasha la doortay ayaa ah go'aamo muhiim u ah kansarka sida Myelodysplastic Syndrome. Bukaannada Myelodysplastic Syndrome iyo shakhsiyaadka leh khatarta hidde-sidaha waxay had iyo jeer qabaan su'aashan: "Waa maxay cuntooyinka iyo nafaqooyinka nafaqada ee lagu taliyey aniga iyo kuwa aan ahayn?" Waxaa jira aaminsanaan guud oo ah fikrad khaldan oo ah in dhammaan cuntooyinka dhirta ku salaysan ay faa'iido yeelan karaan ama aysan ahayn laakiin aan waxyeello lahayn. Cuntooyinka qaarkood iyo kaabisyada qaarkood waxay faragelin karaan daawaynta kansarka ama waxay kor u qaadi karaan wadayaasha dariiqyada molecular ee kansarka.

Waxaa jira noocyo kala duwan oo tilmaamayaasha kansarka sida Myelodysplastic Syndrome, mid kasta oo leh hidde-sidaha burooyinka oo kala duwan oo leh kala duwanaansho genomic oo dheeraad ah oo qof kasta ah. Intaa waxaa dheer daawaynta kansar kasta iyo kiimoterabi kasta waxay leeyihiin hab wax-qabad oo gaar ah. Cunto kasta sida Wax Gourd waxay ka kooban tahay noocyo kala duwan oo bioactives ah oo tirooyin kala duwan leh, kuwaas oo saameyn ku leh noocyo kala duwan oo kala duwan oo ah dariiqyada biochemical. Qeexida nafaqeynta shakhsi ahaaneed waa talooyinka cuntada ee gaarka ah ee tilmaamaya kansarka, daawaynta, genetics, qaab nololeedka iyo arrimo kale. Go'aannada shakhsiyaynta nafaqada ee kansarka waxay u baahan yihiin aqoonta bayoolajiga kansarka, sayniska cuntada iyo fahamka daaweynta kemotherabi ee kala duwan. Ugu dambeyntii marka ay jiraan isbeddel daaweyn ama genomics cusub ayaa la aqoonsaday - shakhsiyeynta nafaqeynta waxay u baahan tahay dib-u-qiimeyn.

Xalka shakhsiyaynta nafaqeynta ee addon ayaa ka dhigaysa go'aan qaadashada mid fudud oo meesha ka saaraysa dhammaan mala-awaalka ka jawaabaya su'aasha, "Cunto noocee ah ayaan dooran karaa ama ma dooran karaa Myelodysplastic Syndrome?". Kooxda edbinta badan ee addon waxaa ka mid ah dhakhaatiirta kansarka, saynisyahano caafimaad, injineerada software iyo saynisyahano xogta.

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• Formononetin waxay xakameysaa kororka kansarka sanbabada unugga aan yareyn ee bini'aadamka iyada oo la adeegsanayo xiritaanka wareegga unugyada iyo apoptosis.
• Melatonin iyo fitamiin D3 si isku mid ah ayaa hoos u dhigaya Akt iyo MDM2 taasoo horseedaysa joojinta koritaanka TGFβ-1-ku-tiirsanaanta unugyada kansarka naasaha.
• In vitro iyo in vivo dhaqdhaqaaqa antitumor ee neochlorogenic acid ee unugyada kansarka gastric ee bini'aadamka ayaa lagu kabay jiilka ROS, luminta awoodda xuubka mitochondrial iyo soo-saarka apoptosis.
• Lipidomics functional: Palmitic acid waxay wax u dhimaysaa horumarinta kansarka hepatocellular iyada oo wax ka beddelaysa dareeraha xuubka iyo dheef-shiid kiimikaadka gulukooska.
• https://rarediseases.org/rare-diseases/myelodysplastic-syndromes/#:~:text=General%20symptoms%20associated%20with%20MDS,or%20develop%20into%20acute%20leukemia.
• https://www.leukaemia.org.au/blood-cancer-information/types-of-blood-cancer/myelodysplastic-syndromes
• https://www.ncbi.nlm.nih.gov/books/NBK534126