Cuntooyinka loogu talagalay Kansarka Unugga Squamous-ka ee Dabada!

Hordhac

Cuntooyinka loogu talagalay Kansarka Unugyada Dabada ee Dabada waa in loo shakhsiyeeyaa qof kasta oo waa in sidoo kale la qabsadaa marka daaweynta kansarka ama hidde-sidaha buradu ay isbeddelaan. Shakhsiyaynta iyo la qabsiga waa in ay tixgelisaa dhammaan maaddooyinka firfircoon ama bioactives ee ku jira cuntooyinka kala duwan marka loo eego bayooloojiyada unugyada kansarka, genetics, daawaynta, xaaladaha qaab nololeedka iyo doorbidka cuntada. Sidaa darteed iyadoo nafaqadu ay tahay mid ka mid ah go'aamada aadka muhiimka u ah bukaanka kansarka iyo qofka halista ugu jira kansarka inuu sameeyo - sida loo doorto cuntooyinka uu cuno maaha hawl fudud.

Kansarka dabada ee Squamous-ka, oo ah nooc gaar ah oo kansarka futada ah, waxa lagu gartaa isbeddelka xun ee unugyada squamous-ka ee kanaalka dabada. Xaaladdan waxaa lagu sifeeyay nidaamka codeing ICD-10, kaas oo ka caawiya aqoonsiga iyo dabagalka diiwaannada caafimaadka. Daawaynta kansarka dabada ee dabada waxay ku lug leedahay habab badan oo kala duwan, oo ay ku jiraan kiimoterabi, daawaynta shucaaca, iyo mararka qaarkood qalliin, taas oo ku xidhan heerka iyo heerka cudurka. Fahamka dabeecadda iyo maareynta kansarkan waa muhiim, maadaama ogaanshaha hore iyo daawaynta ku habboon ay si weyn u saameyn karto natiijooyinka bukaanka. Ka warqabka calaamadaha iyo arrimaha khatarta ah ee la xidhiidha kansarka sanbabada unugyada dabada ayaa lagama maarmaan u ah ogaanshaha waqtiga iyo daaweynta waxtarka leh.

Kansarka unugyada dabada ee squamous-ka miyay muhiim u tahay khudaarta, miraha, lawska, miraha la cuno?

Su'aasha nafaqeynta ee aadka u badan ee ay weydiiyaan bukaannada kansarka iyo shakhsiyaadka halista ugu jira hidde-sidaha kansarka waa - kansarka sida Kansarka Squamous Cell squamous miyay muhiim u tahay cuntooyinka aan cuno iyo kuwa aanan samayn? Mise haddii aan raaco cunto ku salaysan geedka ma ku filan tahay kansarka sida Kansarka Squamous Cell squamous?

Tusaale ahaan miyay muhiim tahay haddii khudaarta Ivy Gourd la isticmaalo in ka badan marka loo eego Pokeweed American? Miyay wax farqi ah samaynaysaa haddii khudaarta Pummelo laga door bido Java Plum? Sidoo kale haddii doorashooyin la mid ah loo sameeyo nuts/abuurka sida Black Walnut oo ka sarreeya Chestnut Yurub iyo garaacyada sida Moth Bean oo ka sarreeya digirta cagaaran. Oo haddii waxa aan cuno ay arrintu khusayso - haddaba sidee loo aqoonsan karaa cuntooyinka lagu taliyay Kansarka Squamous Cell squamous-ka oo jawaab isku mid ah ma u tahay qof kasta oo leh isla cudurka ama khatarta hidde-sidaha?

Haa! Cuntooyinka aad cuntid waxay udub dhexaad u yihiin Kansarka Unugga Squamous Cell!

Talooyinka cuntadu waxay noqon karaan kuwo isku mid ah qof kasta oo way ka duwanaan karaan xitaa ogaanshaha isku midka ah iyo khatarta hidda-socodka.

Dhammaan cuntooyinka ( khudaarta, miraha, lawska, iniinaha, garaaca, saliidaha iwm.) iyo kaabayaasha nafaqadu waxay ka kooban yihiin wax ka badan hal walxo molecular ama bio-actives oo qiyaas iyo tiro kala duwan leh. Walax kasta oo firfircooni waxay leedahay hab u gaar ah oo wax qabad - kaas oo noqon kara firfircooni ama xannibaadda dariiqyada biochemical ee kala duwan. Cuntooyinka si fudud loo sheegay iyo kaabisyada lagu taliyay waa kuwa aan keenin korodhka wadayaasha molecular ee kansarka laakiin la yareeyo. Haddii kale cuntooyinkaas waa inaan lagu talin. Cuntooyinka waxaa ku jira maaddooyin badan oo firfircoon - markaa marka la qiimeynayo cuntooyinka iyo kaabayaasha waxaad u baahan tahay inaad tixgeliso saameynta dhammaan maaddooyinka firfircoon si wadajir ah halkii aad ka ahaan lahayd mid gaar ah.

Tusaale ahaan Pummelo waxa ku jira maaddooyinka firfircoon ee Curcumin, Apigenin, Quercetin, Lupeol, Formononetin. Plum Java wuxuu ka kooban yahay curcumin, Apigenin, Ellagic Acid, Lupeol, Formononetin iyo kuwo kale oo suurtagal ah.

Khalad caadi ah oo la sameeyo marka la go'aaminayo oo la dooranayo cuntooyinka la cuno ee Kansarka Unugga Squamous Cell - waa in la qiimeeyo oo kaliya maaddooyinka firfircoon ee la doortay ee ku jira cuntooyinka oo la iska indhatiro inta kale. Sababtoo ah maaddooyinka kala duwan ee firfircoon ee ku jira cuntooyinka ayaa laga yaabaa inay saameyn iska soo horjeeda ku yeeshaan darawalada kansarka - ma qaadan kartid maaddooyinka firfircoon ee cuntooyinka iyo kaabayaasha si aad u go'aansato nafaqeynta Kansarka Squamous Cell Dabada.

HAA – DOORASHOOYINKA CUNTADA EE KANSARKA WAXAY U TAAGAN YAHAY. GO'AANKA NAFAQADA waa in ay tixgeliyaan dhammaan walxaha firfircoon ee CUNTADA.

Xirfadaha Looga Baahan Yahay Nafaqaynta Shakhsiyaynta Ee Kansarka Dabada Squamous Cell?

Nafaqada shakhsi ahaaneed ee kansarrada sida Kansarka Squamous Cell ee Dabada waxay ka kooban tahay cuntooyin/kaabyo lagu taliyey; Cuntooyinka aan lagu talin/kabka tusaale ahaan cunto karinta kuwaas oo mudnaanta siiya isticmaalka cuntooyinka lagu taliyay. Tusaale nafaqeynta gaarka ah ayaa tan lagu arki karaa link.

Go'aaminta cuntooyinka lagu taliyay iyo in kale waa mid aad u dhib badan, waxay u baahan tahay khibrad ku saabsan bayoolajiga dabada ee Kansarka, sayniska cuntada, genetics, biochemistry oo ay weheliso faham wanaagsan oo ku saabsan sida daawaynta kansarku u shaqeyso iyo baylahda la xidhiidha kuwaas oo daawadu ay ku joojin karto waxtarka.

Khibradda UGU YAR EE AQOONTA EE LOO BAAHAN YAHAY NAFAQADA SHAQSIYADEEDKA KANSARKA WAA: NOLOLIGA KANSARKA, CUNTADA CUNTADA, DAAWAYNTA KANSARKA IYO HIDDAHA HIDDAHA.

Astaamaha kansarka sida Kansarka Squamous Cell Dabada

Dhammaan kansarrada sida Kansarka unugga Squamous-ka ee futada waxaa lagu sifeyn karaa waddooyin gaar ah oo biochemical ah - dariiqooyinka saxiixa ee Kansarka unugyada Dabada. Dariiqooyin kiimikaad sida MAPK Signaling, NFKB Signaling, PI3K-AKT-MTOR Signaling, Oncogenic Histone Methylation waa qayb ka mid ah qeexida saxeexa Kansarka Unug Squamous-ka ee futada. Hidde-sideyaasha kansarku qof walba wuu ka duwanaan karaa sidaas darteed saxiixooda gaarka ah ee kansarku wuxuu noqon karaa mid gaar ah.

Daawaynta waxtarka u leh Kansarka Unugyada Squamous-ka ee futada waxay u baahan yihiin inay ogaadaan dariiqooyinka biochemical ee la xidhiidha saxeexa bukaan kasta oo kansar ah iyo shakhsiga khatarta hidde-sidaha. Sidaa darteed daawayn kala duwan oo leh habab kala duwan oo ficil ah ayaa waxtar u leh bukaanada kala duwan. Si la mid ah iyo sababo la mid ah cuntooyinka iyo kaabista waxay u baahan yihiin in shaqsi kasta loo gaaryeelo. Sidaa darteed cuntooyinka iyo kaabista qaar ayaa lagula taliyaa Kansarka Unugyada Squamous-ka ee Dabada marka la qaadanayo daawaynta Kansarka Mitomycin, cuntooyinka iyo kaabista qaarkoodna laguma talinayo.

Ilaha sida cBioPortal iyo qaar kale oo badan ayaa bixiya xogta bukaan-socodka ee aan la magacaabin ee laga helay tijaabooyinka bukaan-socodka ee dhammaan calaamadaha kansarka. Xogtan waxay ka kooban tahay tafaasiisha daraasadda tijaabada caafimaad sida cabbirka saamiga / tirada bukaannada, kooxaha da'da, jinsiga, qowmiyadda, daawaynta, goobta burooyinka iyo isbeddellada hidde-sidaha.

KMT2D, PIK3CA, EP300, FBXW7 iyo PTEN ayaa ah kuwa ugu sarreeya ee la soo sheegay hidde-sideyaasha Kansarka Unugyada Dabada. KMT2D waxaa lagu soo warramey 27.0 % bukaannada matala dhammaan tijaabooyinka caafimaad. PIK3CA ayaa lagu soo waramayaa in 23.8 %. Isku darka xogta bukaanka ee dadweynaha ayaa daboolaya da'aha laga bilaabo ilaa . 41.9 % xogta bukaanka waxaa loo aqoonsaday rag. Biology-ga Kansarka ee Dabada Squamous-ka oo ay weheliso hidde-sideyaasha la soo sheegay ayaa si wada jir ah u qeexaya dariiqooyinka biochemical ee saxeexa dadweynaha ee kansarkan. Haddii genetics-ka burada kansarka shakhsi ahaaneed ama hiddo-wadaha ka qaybqaata khatarta sidoo kale waa la yaqaan markaa waa in sidoo kale loo isticmaalo shakhsiyaynta nafaqada.

Dookhyada nafaqeynta waa in ay iswaafaqaan shaqsi walba saxiixiisa.

Cuntooyinka iyo Kaabayaasha Kansarka Unugyada Dabada

Bukaanka Kansarka

Bukaanjiifka kansarka ee ku jira daawaynta ama daryeelka palliative waxay u baahan yihiin inay go'aan ka gaadhaan cuntada iyo kaabista - kaloriinta cuntada ee loo baahan yahay, maaraynta waxyeellooyin kasta oo daawaynta iyo sidoo kale hagaajinta maaraynta kansarka. Dhammaan cuntooyinka dhirta ku salaysan maaha kuwo siman oo doorashada iyo kala horraysiinta cuntooyinka kuwaas oo shakhsi ahaan loo habeeyey oo loo habeeyey daawaynta kansarka ee socota waa muhiim oo dhib badan. Waa kuwan tusaalayaal siinaya tilmaamo lagu samaynayo go'aannada nafaqada.

Dooro khudradda IVY GOURD ama AMERICAN PAKEWEED?

Khudaarta Ivy Gourd waxay ka kooban tahay waxyaabo badan oo firfircoon ama bioactives sida Beta-sitosterol, Linolenic Acid, Vitamin C, Linoleic Acid. Maaddooyinkan firfircooni waxay wax ka qabtaan dariiqooyin kiimikaad oo kala duwan sida Angiogenesis, NFKB Signaling, Cell Cycle iyo Apoptosis iyo kuwa kale. Ivy Gourd ayaa lagula taliyaa Kansarka Unugga Squamous-ka ee Dabada marka daawaynta kansarka ee socota ay tahay Mitomycin. Tani waa sababta oo ah Ivy Gourd waxay wax ka beddeshaa dariiqyada biochemical ee si cilmiyeysan loo soo sheegay si loo dareemo saameynta Mitomycin.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee ku jira khudradda Pokeweed American waa Curcumin, Apigenin, Quercetin, Lupeol, Formononetin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida WNT Beta Catenin Signaling, Signaling Cell Stem iyo Dayactirka DNA iyo kuwa kale. Pokeweed American laguma talinayo Kansarka Dabada ee Squamous-ka marka daawaynta kansarka ee socota ay tahay Mitomycin sababtoo ah waxay wax ka beddeshaa dariiqyada biochemical ee ka dhigaya daaweynta kansarku mid adkaysi u leh ama aan ka jawaabin.

GOORKA IVY ee khudaarta ah waxaa lagula taliyaa PAKEweed AMERICA oo loogu talagalay Kansarka unugga dabada iyo daawaynta Mitomycin.

Dooro Miraha JAVA PLUM ama PUMMELO?

Khudradu waxay ka kooban tahay waxyaabo badan oo firfircoon ama bioactives sida Curcumin, Apigenin, Ellagic Acid, Lupeol, Formononetin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimiko oo kala duwan sida NFKB Signaling, JAK-STAT Signaling, PI3K-AKT-MTOR Signaling iyo Focal Adhesion iyo kuwa kale. Java Plum waxa lagula taliyaa Kansarka Unugyada Squamous-ka ee Dabada marka daawaynta kansarka ee socota ay tahay Mitomycin. Tani waa sababta oo ah Java Plum waxay wax ka beddeshaa dariiqyada biochemical ee si cilmiyeysan loo soo sheegay si loo dareemo saameynta Mitomycin.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee ku jira miro Pummelo waa Curcumin, Apigenin, Quercetin, Lupeol, Formononetin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida WNT Beta Catenin Signaling iyo Dayactirka DNA iyo kuwa kale. Pummelo laguma talinayo Kansarka Dabada ee Squamous-ka marka daawaynta kansarka ee socota ay tahay Mitomycin sababtoo ah waxay wax ka beddeshaa dariiqyada biochemical ee ka dhigaya daawaynta kansarku mid adkaysi u leh ama aan ka jawaabin.

FRUIT JAVA Plum waxa lagula talinayaa PUMMELO oo loogu talagalay Kansarka Unugyada Squamous-ka ee Dabada iyo daawaynta Mitomycin.

Dooro Nut BLACK WALNUT ama LAABKA YURUB?

Walnut madow waxaa ku jira waxyaabo badan oo firfircoon ama bioactives sida Curcumin, Apigenin, Quercetin, Ellagic Acid, Lupeol. Maaddooyinkan firfircooni waxay wax ka qabtaan dariiqooyin kiimikaad oo kala duwan sida NFKB Signaling, Cell Cycle, TWEAK Signaling iyo Apoptosis iyo kuwa kale. Walnut Madow waxa lagula taliyaa Kansarka Unugga Squamous-ka ee futada marka daawaynta kansarka ee socota ay tahay Mitomycin. Tani waa sababta oo ah Walnut Black waxay wax ka beddeshaa dariiqyada biochemical ee si cilmiyeysan loo soo sheegay si loo dareemo saameynta Mitomycin.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee ku jira Chestnut Yurub waa Curcumin, Apigenin, Quercetin, Ellagic Acid, Lupeol. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida WNT Beta Catenin Signaling, Signaling Cell Stem iyo Dayactirka DNA iyo kuwa kale. Chestnut Yurub laguma talinayo Kansarka Dabada ee Squamous Cell marka daawaynta kansarka ee socota ay tahay Mitomycin sababtoo ah waxay wax ka beddeshaa dariiqyada biochemical ee ka dhigaya daawaynta kansarku mid adkaysi u leh ama aan ka jawaabin.

Walaska Madow waxaa lagula talinayaa laabta Yurub si loogu daaweeyo Kansarka Unugyada Dabada iyo daawaynta Mitomycin.

Shakhsiyaadka leh Khatarta Hidde ee Kansarka

Su'aasha ay weydiiyaan shakhsiyaadka leh khatarta hidde-sidaha ee Kansarka Unugga Squamous Cell ama taariikhda qoyska waa "Maxaan Cunnaa Si Ka Duwan Kii Hore?" iyo sida ay tahay inay doortaan cuntooyinka iyo kaabista si loo maareeyo khatarta cudurka. Maadaama khatarta kansarku aanay jirin wax la qaban karo marka la eego daawaynta - go'aamada cuntooyinka iyo kaabista ayaa noqda mid muhiim ah iyo mid ka mid ah waxyaallaha aadka u yar ee la qaban karo. Dhammaan cuntooyinka dhirta ku salaysan maaha kuwo siman oo ku salaysan hidde-sidaha la aqoonsaday iyo saxeexa dariiqa - doorashooyinka cuntada iyo kaabista waa in la shakhsiyeeyo.

Dooro basbaaska cagaaran ee cagaaran ama BROCCOLI?

Basbaaska cagaaran ee cagaarka ah waxaa ku jira waxyaabo badan oo firfircoon ama bioactives sida Curcumin, Quercetin, Resveratrol, Catechol, Linalool. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida Inositol Phosphate Signaling, Angiogenesis, Insulin Signaling iyo P53 Signaling iyo kuwa kale. Cagaaran Basbaas ah ayaa lagula talinayaa halista kansarka unugyada squamous-ka ee futada marka khatarta hidde ee la xiriirta ay tahay EP300. Tani waa sababta oo ah Green Bell Pepper waxay kordhisaa dariiqyada biochemical ee ka soo horjeeda wadayaasha saxeexa.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee ku jira Broccoli khudradda waa Curcumin, Quercetin, Resveratrol, Catechol, Lupeol. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida Insulin Signaling iyo P53 Signaling iyo kuwa kale. Brokoli laguma talinayo marka khatarta ah Kansarka Unug Squamous-ka ee futada marka khatarta hidda-socodka la xiriirta ay tahay EP300 sababtoo ah waxay kordhisaa dariiqooyinka saxiixa.

Basbaaska cagaaran ee khudaarta ah ayaa lagula talinayaa brooccoli ee loogu talagalay EP300 khatarta hidda-socodka ee kansarka.

Dooro TAMARIND Miraha ama GRAPEFRUIT?

Tamarind miraha waxaa ku jira waxyaabo badan oo firfircoon ama bioactives sida Curcumin, Apigenin, Catechol, Linalool, Lupeol. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida PI3K-AKT-MTOR Signaling, Insulin Signaling iyo Hypoxia iyo kuwa kale. Tamarind waxaa lagula talinayaa halista kansarka unugyada Squamous-ka ee dabada marka khatarta hidda-socodka la xiriirta ay tahay EP300. Tani waa sababta oo ah Tamarind waxay kordhisaa dariiqyada biochemical ee ka soo horjeeda wadayaasha saxiixa.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee ku jira canabka miraha waa Curcumin, Catechol, Lupeol, Lycopene, Formononetin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida Insulin Signaling iyo PI3K-AKT-MTOR Signaling iyo kuwa kale. Canabka laguma talinayo marka halista kansarka dabada ee Squamous cell marka khatarta hidde la xidhiidha ay tahay EP300 sababtoo ah waxay kordhisaa dariiqooyinka saxeexa.

FRUIT TAMARIND WAXAA LAGU TALAGAY INABA EP300 KHATARTA HIDDAHA EE KANSARKA.

Dooro lowska BUTTERNUT ama HICKORY NUT?

Butternut wuxuu ka kooban yahay waxyaabo badan oo firfircoon ama bioactives sida Curcumin, Apigenin, Catechol, Lupeol, Lycopene. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida PI3K-AKT-MTOR Signaling, Signaling Insulin-ka iyo P53 Signaling iyo kuwa kale. Butternut ayaa lagula talinayaa halista kansarka unugyada squamous-ka ee futada marka khatarta hidde ee la xiriirta ay tahay EP300. Tani waa sababta oo ah Butternut waxay kordhisaa dariiqyada biochemical ee ka soo horjeeda wadayaasha saxiixa.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee Hickory Nut waa Curcumin, Apigenin, Catechol, Lupeol, Lycopene. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida Insulin Signaling iyo PI3K-AKT-MTOR Signaling iyo kuwa kale. Hickory Nut laguma talinayo marka halista kaansarka unugga dabada ee squamous-ka marka khatarta hidde-sidaha la xidhiidha ay tahay EP300 sababtoo ah waxay kordhisaa dariiqooyinka saxeexa.

BUTTERNUT ayaa lagula talinayaa HICKORY nuts oo loogu talagalay EP300 Khatarta Hidde ee Kansarka.

In Gabagabo

Cuntooyinka iyo Kaabayaasha la doortay ayaa ah go'aamo muhiim u ah kansarrada sida Kansarka unugyada Squamous-ka ee futada. Bukaannada Kansarka ee Unugga Squamous-ka dabada iyo shakhsiyaadka leh khatarta hidde-sidaha waxay had iyo jeer qabaan su'aashan: "Waa maxay cuntooyinka iyo kaabisyada nafaqeynta ee lagu taliyay aniga iyo kuwa aan ahayn?" Waxaa jira aaminsanaan guud oo ah fikrad khaldan oo ah in dhammaan cuntooyinka dhirta ku salaysan ay faa'iido yeelan karaan ama aysan ahayn laakiin aan waxyeello lahayn. Cuntooyinka qaarkood iyo kaabisyada qaarkood waxay faragelin karaan daawaynta kansarka ama waxay kor u qaadi karaan wadayaasha dariiqyada molecular ee kansarka.

Waxaa jira noocyo kala duwan oo calaamado kansar ah sida Kansarka Squamous Cell ee Futada, mid kasta oo leh hidde-sidaha burooyinka kala duwan oo leh kala duwanaansho genomic dheeraad ah oo qof kasta ah. Intaa waxaa dheer daawaynta kansar kasta iyo kiimoterabi kasta waxay leeyihiin hab wax-qabad oo gaar ah. Cunto kasta sida Ivy Gourd waxay ka kooban tahay noocyo kala duwan oo bioactives ah oo tirooyin kala duwan leh, kuwaas oo saameyn ku leh noocyo kala duwan oo kala duwan oo ah dariiqyada biochemical. Qeexida nafaqeynta shakhsi ahaaneed waa talooyinka cuntada ee gaarka ah ee tilmaamaya kansarka, daawaynta, genetics, qaab nololeedka iyo arrimo kale. Go'aannada shakhsiyaynta nafaqada ee kansarka waxay u baahan yihiin aqoonta bayoolajiga kansarka, sayniska cuntada iyo fahamka daaweynta kemotherabi ee kala duwan. Ugu dambeyntii marka ay jiraan isbeddel daaweyn ama genomics cusub ayaa la aqoonsaday - shakhsiyeynta nafaqeynta waxay u baahan tahay dib-u-qiimeyn.

Xalka shakhsiyaynta nafaqeynta ee addon ayaa ka dhigaysa go'aan qaadashada mid fudud oo meesha ka saaraysa dhammaan malo awaalka ee ka jawaabista su'aasha, "Cunto noocee ah ayaan dooran karaa ama ma dooran karaa Kansarka Unugga Squamous Cell ee Futada?". Kooxda edbinta badan ee addon waxaa ka mid ah dhakhaatiirta kansarka, saynisyahano caafimaad, injineerada software iyo saynisyahano xogta.

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