Hordhac
Cuntooyinka loogu talagalay Adamantinomatous Craniopharyngiomas waa in loo shakhsiyeeyaa qof kasta oo waa in sidoo kale la qabsadaa marka daaweynta kansarka ama isbeddelka hidda-socodka burooyinka. Shakhsiyaynta iyo la qabsiga waa in ay tixgelisaa dhammaan maaddooyinka firfircoon ama bioactives ee ku jira cuntooyinka kala duwan marka loo eego bayooloojiyada unugyada kansarka, genetics, daawaynta, xaaladaha qaab nololeedka iyo doorbidka cuntada. Sidaa darteed iyadoo nafaqadu ay tahay mid ka mid ah go'aamada aadka muhiimka u ah bukaanka kansarka iyo qofka halista ugu jira kansarka inuu sameeyo - sida loo doorto cuntooyinka uu cuno maaha hawl fudud.
Adamantinomatous Craniopharyngiomas miyay macno u leedahay waxa khudaarta, miraha, lawska, iniinaha la cuno?
Su'aasha nafaqeynta ee aadka u badan ee ay weydiiyaan bukaannada kansarka iyo shakhsiyaadka halista ugu jira hidde-sidaha kansarka waa - kansarka sida Adamantinomatous Craniopharyngiomas miyay macno u leedahay cuntooyinka aan cuno iyo kuwa aanan samayn? Mise haddii aan raaco cunto ku salaysan geedka ayaa ku filan kansarka sida Adamantinomatous Craniopharyngiomas?
Tusaale ahaan miyay muhiim tahay haddii basbaaska qudaarta (capsicum) la isticmaalo in ka badan marka loo eego Brokoliga Shiinaha? Miyay wax farqi ah samaynaysaa haddii midhaha Canabka laga door bido Jujube? Sidoo kale haddii xulashooyin la mid ah loo sameeyo lawska/abuurka sida Macadamia Nut oo ka badan Butternut iyo garaaca wadnaha sida Bean jaalaha ah oo ka sarreeya bean moth. Oo haddii waxa aan cuno ay arrintu khusayso - markaa sidee qofku u aqoonsan karaa cuntooyinka lagu taliyay Adamantinomatous Craniopharyngiomas oo ma isku mid baa jawaab u tahay qof kasta oo leh isla cudurka ama khatarta hidde-sidaha?
Haa! Cuntooyinka aad cunayso waxay u tahay Adamantinomatous Craniopharyngiomas!
Talooyinka cuntadu waxay noqon karaan kuwo isku mid ah qof kasta oo way ka duwanaan karaan xitaa ogaanshaha isku midka ah iyo khatarta hidda-socodka.
Dhammaan cuntooyinka ( khudaarta, miraha, lawska, iniinaha, garaaca, saliidaha iwm.) iyo kaabayaasha nafaqadu waxay ka kooban yihiin wax ka badan hal walxo molecular ama bio-actives oo qiyaas iyo tiro kala duwan leh. Walax kasta oo firfircooni waxay leedahay hab u gaar ah oo wax qabad - kaas oo noqon kara firfircooni ama xannibaadda dariiqyada biochemical ee kala duwan. Cuntooyinka si fudud loo sheegay iyo kaabisyada lagu taliyay waa kuwa aan keenin korodhka wadayaasha molecular ee kansarka laakiin la yareeyo. Haddii kale cuntooyinkaas waa inaan lagu talin. Cuntooyinka waxaa ku jira maaddooyin badan oo firfircoon - markaa marka la qiimeynayo cuntooyinka iyo kaabayaasha waxaad u baahan tahay inaad tixgeliso saameynta dhammaan maaddooyinka firfircoon si wadajir ah halkii aad ka ahaan lahayd mid gaar ah.
Tusaale ahaan canabka waxaa ku jira maaddooyinka firfircoon ee Formononetin, Eugenol, Phloretin, Umbelliferone, Naringenin. Jujubena waxaa ku jira maaddooyin firfircoon oo Quercetin, Myricetin, Formononetin, Eugenol, Phloretin iyo suurtagal ahaan kuwa kale.
Qalad caadi ah oo la sameeyo marka la go'aaminayo oo la dooranayo cuntooyinka la cuno ee Adamantinomatous Craniopharyngiomas - waa in la qiimeeyo oo kaliya maaddooyinka firfircoon ee la doortay ee ku jira cuntooyinka oo la iska indhatiro inta kale. Sababtoo ah maaddooyinka kala duwan ee firfircoon ee ku jira cuntooyinka ayaa laga yaabaa inay saameyn iska soo horjeeda ku yeeshaan darawalada kansarka - ma qaadan kartid maaddooyinka firfircoon ee cuntooyinka iyo kaabayaasha si aad go'aan uga gaarto Adamantinomatous Craniopharyngiomas.
HAA – DOORASHOOYINKA CUNTADA EE KANSARKA WAXAY U TAAGAN YAHAY. GO'AANKA NAFAQADA waa in ay tixgeliyaan dhammaan walxaha firfircoon ee CUNTADA.
Xirfadaha Looga Baahan Yahay Nafaqaynta Shakhsiyaynta ee Adamantinomatous Craniopharyngiomas?
Nafaqada shakhsi ahaaneed ee kansarrada sida Adamantinomatous Craniopharyngiomas waxay ka kooban tahay cuntooyin/kaabyo lagu taliyey; Cuntooyinka aan lagu talin/kabka tusaale ahaan cunto karinta kuwaas oo mudnaanta siiya isticmaalka cuntooyinka lagu taliyay. Tusaale nafaqeynta gaarka ah ayaa tan lagu arki karaa link.
Go'aaminta cuntooyinka lagu taliyay iyo kuwa aan lagu talin waa mid aad u adag, oo u baahan khibrad ku saabsan Adamantinomatous Craniopharyngiomas bayoloji, sayniska cuntada, genetics, biochemistry oo ay weheliso faham wanaagsan oo ku saabsan sida daawaynta kansarka u shaqeyso iyo baylahda la xidhiidha kuwaas oo daaweyntu ay joojin karto waxtarka.
Khibradda UGU YAR EE AQOONTA EE LOO BAAHAN YAHAY NAFAQADA SHAQSIYADEEDKA KANSARKA WAA: NOLOLIGA KANSARKA, CUNTADA CUNTADA, DAAWAYNTA KANSARKA IYO HIDDAHA HIDDAHA.
Cuntooyinka la Cuno Ka Dib Baaritaanka Kansarka!
Ma jiraan laba kansar oo isku mid ah. Ka gudub tilmaamaha guud ee nafaqada ee qof walba oo samee go'aanno shaqsiyeed oo ku saabsan cuntada iyo kaabayaasha si kalsooni leh.
Astaamaha kansarka sida Adamantinomatous Craniopharyngiomas
Dhammaan kansarrada sida Adamantinomatous Craniopharyngiomas waxaa lagu sifeyn karaa waddooyin gaar ah oo biochemical ah - dariiqooyinka saxiixa ee Adamantinomatous Craniopharyngiomas. Dariiqooyinka biochemical sida RAS-RAF Signaling, DNA Repair, Epigenetics Kansarka Oncogenic, Oncogenic Histone Methylation waa qayb ka mid ah qeexida saxiixa Adamantinomatous Craniopharyngiomas. Hidde-sideyaasha kansarku qof walba wuu ka duwanaan karaa sidaas darteed saxiixooda gaarka ah ee kansarku wuxuu noqon karaa mid gaar ah.
Daawaynta waxtarka u leh Adamantinomatous Craniopharyngiomas waxay u baahan yihiin inay gartaan saxeexa dariiqooyinka biochemical ee la xidhiidha bukaan kasta oo kansar ah iyo shakhsi ahaan khatarta hidde-sidaha. Sidaa darteed daawayn kala duwan oo leh habab kala duwan oo ficil ah ayaa waxtar u leh bukaanada kala duwan. Si la mid ah iyo sababo la mid ah cuntooyinka iyo kaabista waxay u baahan yihiin in shaqsi kasta loo habeeyo. Sidaa awgeed cuntooyinka iyo kaabayaasha qaarkood ayaa lagula taliyaa Adamantinomatous Craniopharyngiomas marka la qaadanayo daawaynta kansarka Shucaaca, iyo cuntooyinka qaar iyo kaabista laguma talinayo.
Ilaha sida cBioPortal iyo qaar kale oo badan ayaa bixiya xogta bukaan-socodka ee aan la magacaabin ee laga helay tijaabooyinka bukaan-socodka ee dhammaan calaamadaha kansarka. Xogtan waxay ka kooban tahay tafaasiisha daraasadda tijaabada caafimaad sida cabbirka saamiga / tirada bukaannada, kooxaha da'da, jinsiga, qowmiyadda, daawaynta, goobta burooyinka iyo isbeddellada hidde-sidaha.
DNMT3A, TET2, BARD1, NF1 iyo NSD1 waa hiddo-wadaha ugu sarreeya ee la soo sheegay ee Adamantinomatous Craniopharyngiomas. DNMT3A waxaa lagu soo warramey 25.0 % bukaanada matala dhamaan tijaabooyinka kiliinikada. TET2 waxaa lagu soo warramey 25.0 %. Isku darka xogta bukaanka ee dadweynaha ayaa daboolaya da'da 3 ilaa 71. 50.6 % xogta bukaanka waxaa loo aqoonsaday inay yihiin rag. Bayoolajiga Adamantinomatous Craniopharyngiomas oo ay weheliso hidde-sideyaasha la soo sheegay ayaa si wada jir ah u qeexaya dariiqyada biochemical ee saxeexa dadweynaha ee kansarkan. Haddii genetics-ka burada kansarka shakhsi ahaaneed ama hiddo-wadaha ka qaybqaata khatarta sidoo kale waa la yaqaan markaa waa in sidoo kale loo isticmaalo shakhsiyaynta nafaqada.
Dookhyada nafaqeynta waa in ay iswaafaqaan shaqsi walba saxiixiisa.
Cuntada iyo Kaabayaasha loogu talagalay Adamantinomatous Craniopharyngiomas
Bukaanka Kansarka
Bukaanjiifka kansarka ee ku jira daawaynta ama daryeelka palliative waxay u baahan yihiin inay go'aan ka gaadhaan cuntada iyo kaabista - kaloriinta cuntada ee loo baahan yahay, maaraynta waxyeellooyin kasta oo daawaynta iyo sidoo kale hagaajinta maaraynta kansarka. Dhammaan cuntooyinka dhirta ku salaysan maaha kuwo siman oo doorashada iyo kala horraysiinta cuntooyinka kuwaas oo shakhsi ahaan loo habeeyey oo loo habeeyey daawaynta kansarka ee socota waa muhiim oo dhib badan. Waa kuwan tusaalayaal siinaya tilmaamo lagu samaynayo go'aannada nafaqada.
Dooro basbaaska khudaarta ah (CAPSICUM) ama BROCCOLI CHINESE?
Basbaaska qudaarta (capsicum) waxaa ku jira waxyaabo badan oo firfircoon ama bioactives sida Quercetin, Myricetin, Formononetin, Eugenol, Phloretin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida DNA Repair, Epithelial ilaa Mesenchymal Transition, Oxidative Stress iyo kuwa kale. Basbaaska (capsicum) ayaa lagula talinayaa Adamantinomatous Craniopharyngiomas marka daawaynta kansarka ee socota ay tahay Shucaac. Tani waa sababta oo ah Pepper (capsicum) waxay wax ka beddeshaa dariiqyada biochemical ee si cilmiyeysan loo soo sheegay si loo dareemo saameynta shucaaca.
Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee ku jira Brokoli Shiineys ah oo khudaar ah waa Myricetin, Formononetin, Phloretin, Eugenol, Umbelliferone. Maaddooyinkan firfircooni waxay wax ka qabtaan dariiqooyin kiimikaad oo kala duwan sida Cadaadiska Oxidative iyo kuwa kale. Brokoli Shiineys ah laguma talinayo Adamantinomatous Craniopharyngiomas marka daawaynta kansarka ee socota ay tahay Shucaac sababtoo ah waxay wax ka beddeshaa dariiqyada biochemical ee ka dhigaya daawaynta kansarku mid adkaysi u leh ama ka jawaabi kara.
BAsbaaska khudaarta leh (CAPSICUM) ayaa lagula taliyaa BROCCOLI CHINESE AH oo loogu talagalay Adamantinomatous craniopharyngiomas iyo shucaaca daawaynta.
Dooro miraha JUJUBE ama GRAPEFRUIT?
Jujube miraha waxaa ku jira waxyaabo badan oo firfircoon ama bioactives sida Quercetin, Myricetin, Formononetin, Eugenol, Phloretin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida DNA Repair, RAS-RAF Signaling, Epithelial to Mesenchymal Transition iyo Oxidative Stress iyo kuwa kale. Jujube ayaa lagula taliyaa Adamantinomatous Craniopharyngiomas marka daawaynta kansarka ee socota ay tahay Shucaac. Sababtoo ah Jujube waxay wax ka beddeshaa dariiqyada biochemical ee si cilmiyeysan loo soo sheegay si loo dareensiiyo saameynta shucaaca.
Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee ku jira canabka miraha waa Formononetin, Eugenol, Phloretin, Umbelliferone, Naringenin. Maaddooyinkan firfircooni waxay wax ka qabtaan dariiqooyin kiimikaad oo kala duwan sida Cadaadiska Oxidative iyo kuwa kale. Canabka laguma talinayo Adamantinomatous Craniopharyngiomas marka daawaynta kansarka ee socota ay tahay Shucaac sababtoo ah waxay wax ka beddeshaa dariiqyada biochemical ee ka dhigaya daawaynta kansarku mid adkaysi u leh ama aan ka jawaabin.
MIDHAHA JUJUBE AYAA LAGULA TALAGAY GRAPEFRUIT oo loogu talagalay Adamantinomatous Craniopharyngiomas iyo Shucaaca daawaynta.
Dooro lawska MACADAMIA NUT ama BUTTERNUT?
Macadamia Nut waxa ku jira maaddooyin badan oo firfircoon ama bioactives sida Myricetin, Formononetin, Eugenol, Phloretin, Umbelliferone. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida Epithelial ilaa Mesenchymal Transition, JAK-STAT Signaling iyo Oxidative Stress iyo kuwa kale. Macadamia Nut ayaa lagula talinayaa Adamantinomatous Craniopharyngiomas marka daawaynta kansarka ee socota ay tahay Shucaac. Tani waa sababta oo ah Macadamia Nut waxay wax ka beddeshaa dariiqyada biochemical ee si cilmiyeysan loo soo sheegay si loo dareemo saameynta shucaaca.
Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee ku jira Butternut waa Myricetin, Formononetin, Eugenol, Phloretin, Umbelliferone. Maaddooyinkan firfircooni waxay wax ka qabtaan dariiqooyin kiimikaad oo kala duwan sida Cadaadiska Oxidative iyo kuwa kale. Butternut laguma talinayo Adamantinomatous Craniopharyngiomas marka daawaynta kansarka ee socota ay tahay Shucaac sababtoo ah waxay wax ka beddeshaa dariiqyada biochemical ee ka dhigaya daawaynta kansarku mid adkaysi u leh ama aan ka jawaabin.
MACADAMIA NUT waxaa lagula talinayaa in la siiyo baska loogu talagalay Adamantinomatous craniopharyngiomas iyo shucaaca daawaynta.
Shakhsiyaadka leh Khatarta Hidde ee Kansarka
Su'aasha ay weydiiyaan shakhsiyaadka leh khatarta hidde-sidaha ee Adamantinomatous Craniopharyngiomas ama taariikhda qoysku waa "Maxaan Cunnaa si ka duwan kii hore?" iyo sida ay tahay inay doortaan cuntooyinka iyo kaabista si loo maareeyo khatarta cudurka. Maadaama khatarta kansarku aanay jirin wax la qaban karo marka la eego daawaynta - go'aamada cuntooyinka iyo kaabista ayaa noqda mid muhiim ah iyo mid ka mid ah waxyaallaha aadka u yar ee la qaban karo. Dhammaan cuntooyinka dhirta ku salaysan maaha kuwo siman oo ku salaysan hidde-sideyaasha la aqoonsaday iyo Adamantinomatous Craniopharyngiomas dariiqa jidka - doorashooyinka cuntada iyo kaabista waa in la shakhsiyeeyo.
Dooro Qudaar GIANT BUTTERBUR ama Kaabashka CAD?
Khudaarta Giant Butterbur waxay ka kooban tahay waxyaabo badan oo firfircoon ama bioactives ah sida Curcumin, Apigenin, Lycopene, Lupeol, Formononetin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida P53 Signaling, Signaling MAPK, Kansarka Oncogenic Epigenetics iyo RAS-RAF Signaling iyo kuwa kale. Giant Butterbur waxaa lagula talinayaa halista Adamantinomatous Craniopharyngiomas marka khatarta hidde-sidaha la xiriirta ay tahay BARD1. Tani waa sababta oo ah Giant Butterbur waxay kordhisaa dariiqyada biochemical ee ka hortagaya darawallada saxiixa ee Adamantinomatous Craniopharyngiomas.
Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee khudradda cad ee Kaabashka waa Curcumin, Lupeol, Formononetin, Daidzein, Quercetin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida DNA Repair iyo PI3K-AKT-MTOR Signaling iyo kuwa kale. Kaabashka cad laguma talinayo marka halista Adamantinomatous Craniopharyngiomas marka khatarta hidde-sidaha ay tahay BARD1 sababtoo ah waxay kordhisaa dariiqyada saxeexa ee Adamantinomatous Craniopharyngiomas.
BUTTERBUR WAYN OO khudaar ah ayaa lagula taliyaa kaabajka CAD EE BARD1 HALISTA HIDDAHA EE KANSARKA.
Dooro Miraha NANCE ama PUMMELO?
Miraha Nance waxaa ku jira waxyaabo badan oo firfircoon ama bioactives sida Curcumin, Apigenin, Lupeol, Formononetin, Daidzein. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida P53 Signaling, Signaling MAPK, Kansarka Oncogenic Epigenetics iyo RAS-RAF Signaling iyo kuwa kale. Nance waxaa lagula talinayaa halista Adamantinomatous Craniopharyngiomas marka khatarta hidde-sidaha la xiriirta ay tahay BARD1. Tani waa sababta oo ah Nance waxay kordhisaa dariiqooyinka biochemical ee ka hortagaya saxeexyada darawalada Adamantinomatous Craniopharyngiomas.
Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee ku jira miro Pummelo waa Curcumin, Apigenin, Lycopene, Lupeol, Formononetin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida Dayactirka DNA-da, Isbaarada Wareegga Unugyada iyo PI3K-AKT-MTOR Signaling iyo kuwa kale. Pummelo laguma talinayo marka halista Adamantinomatous Craniopharyngiomas marka khatarta hidde-sidaha la xidhiidha ay tahay BARD1 sababtoo ah waxay kordhisaa dariiqyada saxeexa ee Adamantinomatous Craniopharyngiomas.
FRUIT NANCE waxaa lagula talinayaa PUMMELO BARD1 Khatarta hidda-socodka ee Kansarka.
Dooro Nut COMMON HAZELNUT ama NUT BRAZIL?
Hazelnut-ka caadiga ah waxa ku jira maaddooyin badan oo firfircoon ama bioactives sida Curcumin, Lycopene, Lupeol, Formononetin, Daidzein. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida P53 Signaling, Signaling MAPK, MYC Signaling iyo RAS-RAF Signaling iyo kuwa kale. Hazelnut-ka caadiga ah ayaa lagula taliyaa halista Adamantinomatous Craniopharyngiomas marka khatarta hidde-sidaha la xiriirta ay tahay BARD1. Tani waa sababta oo ah Hazelnut Common waxay kordhisaa dariiqooyinka biochemical ee ka hortagaya wadayaasha saxeexa ee Adamantinomatous Craniopharyngiomas.
Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee Brazil nuts waa Curcumin, Ellagic Acid, Lupeol, Formononetin, Daidzein. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida Dayactirka DNA, Calaamadaynta MAPK iyo Calaamadaynta MYC iyo kuwa kale. Nut Brazil laguma talinayo marka halista Adamantinomatous Craniopharyngiomas marka khatarta hidde-sidaha ay tahay BARD1 sababtoo ah waxay kordhisaa dariiqyada saxiixa Adamantinomatous Craniopharyngiomas.
HAZELNUT GUUD ayaa lagula taliyaa BRAZIL NUT BARD1 HALISTA HIDDAHA EE KANSARKA.
In Gabagabo
Cuntooyinka iyo Kaabayaasha la doortay ayaa ah go'aamo muhiim u ah kansarka sida Adamantinomatous Craniopharyngiomas. Bukaannada Craniopharyngiomas Adamantinomatous iyo shakhsiyaadka leh khatarta hidde-sidaha waxay had iyo jeer qabaan su'aashan: "Waa maxay cuntooyinka iyo nafaqooyinka nafaqada ee lagu taliyey aniga iyo kuwa aan ahayn?" Waxaa jira aaminsanaan guud oo ah fikrad khaldan oo ah in dhammaan cuntooyinka dhirta ku salaysan ay faa'iido yeelan karaan ama aysan ahayn laakiin aan waxyeello lahayn. Cuntooyinka qaarkood iyo kaabisyada qaarkood waxay faragelin karaan daawaynta kansarka ama waxay kor u qaadi karaan wadayaasha dariiqyada molecular ee kansarka.
Waxaa jira noocyo kala duwan oo calaamado kansar ah sida Adamantinomatous Craniopharyngiomas, mid kasta oo leh hidde-sidaha burooyinka kala duwan oo leh kala duwanaansho genomic dheeraad ah oo qof kasta ah. Intaa waxaa dheer daawaynta kansar kasta iyo kiimoterabi kasta waxay leeyihiin hab wax-qabad oo gaar ah. Cunto kasta sida basbaaska (capsicum) waxay ka kooban tahay noocyo kala duwan oo bioactives ah oo tirooyin kala duwan leh, kuwaas oo saameyn ku leh noocyo kala duwan oo kala duwan oo ah dariiqyada biochemical. Qeexida nafaqeynta shakhsi ahaaneed waa talooyinka cuntada ee gaarka ah ee tilmaamaya kansarka, daawaynta, genetics, qaab nololeedka iyo arrimo kale. Go'aannada shakhsiyaynta nafaqada ee kansarka waxay u baahan yihiin aqoonta bayoolajiga kansarka, sayniska cuntada iyo fahamka daaweynta kemotherabi ee kala duwan. Ugu dambeyntii marka ay jiraan isbeddel daaweyn ama genomics cusub ayaa la aqoonsaday - shakhsiyeynta nafaqeynta waxay u baahan tahay dib-u-qiimeyn.
Xalka shakhsiyaynta nafaqeynta ee addon ayaa ka dhigaysa go'aan qaadashada mid fudud oo meesha ka saaraysa dhammaan mala-awaalka ka jawaabaya su'aasha, "Cunto noocee ah ayaan dooran karaa ama ma dooran karaa Adamantinomatous Craniopharyngiomas?". Kooxda edbinta badan ee addon waxaa ka mid ah dhakhaatiirta kansarka, saynisyahano caafimaad, injineerada software iyo saynisyahano xogta.
tixraacyada
2) Daaweynta kansarku waxay qaabaysaa muuqaalka fayow ee hematopoiesis ee clonal.