Cuntooyinka loogu talagalay Acral Melanoma!

Hordhac 

Cuntooyinka loogu talagalay Acral Melanoma waa in loo shakhsiyeeyaa qof kasta oo waa in sidoo kale la qabsado marka daaweynta kansarka ama isbeddelka hidda-socodka burooyinka. Shakhsiyaynta iyo la qabsiga waa in ay tixgelisaa dhammaan maaddooyinka firfircoon ama bioactives ee ku jira cuntooyinka kala duwan marka loo eego bayooloojiyada unugyada kansarka, genetics, daawaynta, xaaladaha qaab nololeedka iyo doorbidka cuntada. Sidaa darteed iyadoo nafaqadu ay tahay mid ka mid ah go'aamada aadka muhiimka u ah bukaanka kansarka iyo qofka halista ugu jira kansarka inuu sameeyo - sida loo doorto cuntooyinka uu cuno maaha hawl fudud. 

Acral Melanoma, oo ah nooc gaar ah oo melanoma ah, ayaa caadi ahaan ka muuqda gacmaha, cagaha, iyo ciddiyaha hoostooda, isaga oo soo bandhigaya calaamado kala duwan sida isbeddelka midabka ciddiyaha ama nabarada maqaarka. Noocaan hoose ee melanoma waxaa lagu baari karaa dermoscopic, iyadoo acral lentiginous melanoma inta badan lagu arkay cagta, iyo sawirada muuqaaladaan oo caawinaya fahamka aragga. Tilmaamaha pathology ee melanoma acral, oo ay ku jiraan foomamka goobta, ayaa muhiim u ah ogaanshaha saxda ah, iyo nidaamka koodka ICD-10 ayaa bixiya kala soocideeda. Daaweyntu way kala duwan tahay iyadoo lagu saleynayo heerka iyo nooca isbeddelka, iyadoo saadaasha iyo heerka badbaadada ay ku xiran tahay arrimo ay ka mid yihiin sida degdegga ah ee melanoma u fido iyo guud ahaan gardarrada. Goobaha internetka sida Reddit waxay bixiyaan doodaha bulshada ee khibradaha shakhsi ahaaneed iyo macluumaadka. Fahamka waxa uu u eg yahay melanoma acral iyo waxa sababa, waxay lama huraan u tahay ogaanshaha hore iyo maaraynta waxtarka leh, maadaama nooca melanoma-gani uu ka soo bixi karo meelaha aan sida caadiga ah u soo gaadhin iftiinka qorraxda.

Acral Melanoma miyay muhiim u tahay waxa khudaarta, miraha, lawska, miraha uu qofku cuno?

Su'aasha nafaqeynta ee aadka u badan ee ay weydiiyaan bukaannada kansarka iyo shakhsiyaadka halista ugu jira hidde-sidaha kansarka waa - kansarka sida Acral Melanoma miyay muhiim tahay cuntooyinka aan cuno iyo kuwa aanan samayn? Mise haddii aan raaco cunto ku salaysan geedka ma ku filan tahay kansarka sida Acral Melanoma?

Tusaale ahaan miyay muhiim tahay haddii Kaabashka khudradda la isticmaalo in ka badan marka la barbar dhigo Broccoli Shiinaha? Miyay wax farqi ah samaynaysaa haddii khudaarta Malus (carsaanyo Apple) laga door bido Black Mulberry? Sidoo kale haddii xulashooyin la mid ah loo sameeyo lawska/abuurka sida Hazelnut-ka Caadiga ah oo ka sarreeya Chestnut Yurub iyo garaacyada sida Gram Bean oo ka sarreeya Bean Moth. Oo haddii waxa aan cunaa ay arrintu khusayso - markaa sidee qofku u aqoonsan karaa cuntooyinka lagu taliyey Acral Melanoma oo ma isku mid bay jawaab u tahay qof kasta oo leh isla cudurka ama khatarta hidde-sidaha? 

Haa! Cuntooyinka aad cuntid waxay muhiim u yihiin Acral Melanoma!

Talooyinka cuntadu waxay noqon karaan kuwo isku mid ah qof kasta oo way ka duwanaan karaan xitaa ogaanshaha isku midka ah iyo khatarta hidda-socodka.  

Dhammaan cuntooyinka ( khudaarta, miraha, lawska, iniinaha, garaaca, saliidaha iwm.) iyo kaabayaasha nafaqadu waxay ka kooban yihiin wax ka badan hal walxo molecular ama bio-actives oo qiyaas iyo tiro kala duwan leh. Walax kasta oo firfircooni waxay leedahay hab u gaar ah oo wax qabad - kaas oo noqon kara firfircooni ama xannibaadda dariiqyada biochemical ee kala duwan. Cuntooyinka si fudud loo sheegay iyo kaabisyada lagu taliyay waa kuwa aan keenin korodhka wadayaasha molecular ee kansarka laakiin la yareeyo. Haddii kale cuntooyinkaas waa inaan lagu talin. Cuntooyinka waxaa ku jira maaddooyin badan oo firfircoon - markaa marka la qiimeynayo cuntooyinka iyo kaabayaasha waxaad u baahan tahay inaad tixgeliso saameynta dhammaan maaddooyinka firfircoon si wadajir ah halkii aad ka ahaan lahayd mid gaar ah. 

Tusaale ahaan Malus (carsaanyo Apple) waxaa ku jira maaddooyinka firfircoon ee Lupeol, Isoliquiritigenin, Formononetin, Catechol, Phloretin. Mulberry madow wuxuu ka kooban yahay maaddooyin firfircoon oo Quercetin, Lupeol, Isoliquiritigenin, Formononetin, Catechol iyo suurtagal ah kuwa kale. 

Khalad caadi ah oo la sameeyo marka la go'aaminayo oo la dooranayo cuntooyinka loo cuno Acral Melanoma - waa in la qiimeeyo oo kaliya maaddooyinka firfircoon ee la doortay ee ku jira cuntooyinka oo la iska indhatiro inta kale. Sababtoo ah maaddooyinka kala duwan ee firfircoon ee ku jira cuntooyinka ayaa laga yaabaa inay saameyn iska soo horjeeda ku yeeshaan darawalada kansarka - ma qaadan kartid maaddooyinka firfircoon ee cuntooyinka iyo kaabayaasha si aad go'aan uga gaartid Acral Melanoma. 

HAA – DOORASHOOYINKA CUNTADA EE KANSARKA WAXAY U TAAGAN YAHAY. GO'AANKA NAFAQADA waa in ay tixgeliyaan dhammaan walxaha firfircoon ee CUNTADA.

Xirfadaha Looga Baahan Yahay Nafaqaynta Shakhsiyaynta ee Acral Melanoma?

Nafaqada shakhsi ahaaneed ee kansarka sida Acral Melanoma waxay ka kooban tahay cuntooyin/kaabyo lagu taliyey; Cuntooyinka aan lagu talin/kabka tusaale ahaan cunto karinta kuwaas oo mudnaanta siiya isticmaalka cuntooyinka lagu taliyay. Tusaale nafaqeynta gaarka ah ayaa tan lagu arki karaa link.

Go'aaminta cuntooyinka lagu taliyay iyo kuwa aan lagu talin waa mid aad u adag, oo u baahan khibrad ku saabsan Acral Melanoma bayoloji, sayniska cuntada, genetics, biochemistry oo ay weheliso faham wanaagsan oo ku saabsan sida daawaynta kansarka u shaqeyso iyo baylahda la xidhiidha kuwaas oo daaweyntu ay joojin karto waxtarka.

Khibradda UGU YAR EE AQOONTA EE LOO BAAHAN YAHAY NAFAQADA SHAQSIYADEEDKA KANSARKA WAA: NOLOLIGA KANSARKA, CUNTADA CUNTADA, DAAWAYNTA KANSARKA IYO HIDDAHA HIDDAHA.

Astaamaha kansarka sida Acral Melanoma

Dhammaan kansarrada sida Acral Melanoma waxaa lagu sifeyn karaa nooc gaar ah oo ah dariiqooyinka biochemical - dariiqooyinka saxiixa ee Acral Melanoma. Dariiqooyinka biochemical sida Epigenetics Kansarka Oncogenic, Histone Methylation Suppressive, PI3K-AKT-MTOR Signaling, MAPK Signaling waa qayb ka mid ah qeexida saxeexa Acral Melanoma. Hidde-sideyaasha kansarku qof walba wuu ka duwanaan karaa sidaas darteed saxiixooda gaarka ah ee kansarku wuxuu noqon karaa mid gaar ah.

Daawaynta waxtarka u leh Acral Melanoma waxay u baahan yihiin inay ogaadaan dariiqooyinka biochemical ee la xidhiidha saxeexa bukaanka kansarka iyo shakhsiga khatarta hidde-sidaha. Sidaa darteed daawayn kala duwan oo leh habab kala duwan oo ficil ah ayaa waxtar u leh bukaanada kala duwan. Si la mid ah iyo sababo la mid ah cuntooyinka iyo kaabista waxay u baahan yihiin in shaqsi kasta loo habeeyo. Sidaa awgeed cuntooyinka iyo kaabista qaar ayaa lagula taliyaa Acral Melanoma marka la qaadanayo daawaynta kansarka Checkpoint Pdl1, iyo cuntooyinka qaar iyo kaabista laguma talinayo.

Ilaha sida cBioPortal iyo qaar kale oo badan ayaa bixiya xogta bukaan-socodka ee aan la magacaabin ee laga helay tijaabooyinka bukaan-socodka ee dhammaan calaamadaha kansarka. Xogtan waxay ka kooban tahay tafaasiisha daraasadda tijaabada caafimaad sida cabbirka saamiga / tirada bukaannada, kooxaha da'da, jinsiga, qowmiyadda, daawaynta, goobta burooyinka iyo isbeddellada hidde-sidaha. 

DNMT3A, TET2, PPM1D, ASXL1 iyo ATM ayaa ah kuwa ugu sareeya ee la soo sheegay hiddo-wadaha Acral Melanoma. DNMT3A waxaa lagu soo warramey 31.6 % bukaanada matala dhamaan tijaabooyinka kiliinikada. TET2 ayaa lagu soo warramey 11.8 %. Isku darka xogta bukaan-socodka ee dadweynaha ayaa daboolaya da'da 5 ilaa 96. 60.8 % xogta bukaan-socodka waxaa loo aqoonsaday inay yihiin rag. Biology-ga Acral Melanoma oo ay weheliso genetics-ka la soo sheegay ayaa si wada jir ah u qeexaya dariiqooyinka biochemical ee saxeexa dadweynaha ee kansarkan. Haddii genetics-ka burada kansarka shakhsi ahaaneed ama hiddo-wadaha ka qaybqaata khatarta sidoo kale waa la yaqaan markaa waa in sidoo kale loo isticmaalo shakhsiyaynta nafaqada.

Dookhyada nafaqeynta waa in ay iswaafaqaan shaqsi walba saxiixiisa.

Cuntada iyo Kaabayaasha Acral Melanoma

Bukaanka Kansarka

Bukaanjiifka kansarka ee ku jira daawaynta ama daryeelka palliative waxay u baahan yihiin inay go'aan ka gaadhaan cuntada iyo kaabista - kaloriinta cuntada ee loo baahan yahay, maaraynta waxyeellooyin kasta oo daawaynta iyo sidoo kale hagaajinta maaraynta kansarka. Dhammaan cuntooyinka dhirta ku salaysan maaha kuwo siman oo doorashada iyo kala horraysiinta cuntooyinka kuwaas oo shakhsi ahaan loo habeeyey oo loo habeeyey daawaynta kansarka ee socota waa muhiim oo dhib badan. Waa kuwan tusaalayaal siinaya tilmaamo lagu samaynayo go'aannada nafaqada.  

Dooro kaabashka khudaarta ah ama BROCCOLI CHINESE?

Kaabashka khudradda waxaa ku jira waxyaabo badan oo firfircoon ama bioactives sida Quercetin, Lupeol, Isoliquiritigenin, Formononetin, Catechol. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida Angiogenesis, Calaamadeynta WNT Beta Catenin, Dhaqdhaqaaqa Unugyada Dilaaga Dabiiciga ah iyo Calaamadaynta Interferon iyo kuwa kale. Kaabashka ayaa lagula talinayaa Acral Melanoma marka daawaynta kansarka ee socota ay tahay Checkpoint Pdl1. Tani waa sababta oo ah Kaabashka ayaa wax ka beddela dariiqyada biochemical ee si cilmiyeysan loo soo sheegay si loo dareemo saameynta Checkpoint Pdl1.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee ku jira Broccoli Shiineeska ah waa Lupeol, Isoliquiritigenin, Formononetin, Catechol, Phloretin. Maaddooyinkan firfircooni waxay wax ka qabtaan dariiqooyin kiimiko oo kala duwan sida Dendritic Cell Maturation, CD8 T-cell Activation iyo Presentation Antigen iyo kuwa kale. Brokoli Shiineys ah laguma talinayo Acral Melanoma marka daawaynta kansarka ee socota ay tahay Checkpoint Pdl1 sababtoo ah waxay wax ka beddeshaa dariiqyada biochemical ee ka dhigaya daaweynta kansarku mid adkaysi u leh ama ka jawaabi kara.

Kaabashka khudaarta leh waxaa lagula talinayaa broccoli Shiinaha ee Acral Melanoma iyo Isbaarada daawaynta Pdl1.

Dooro Miraha MULBERRY ama MALUS ( CAB APPLE)?

Mulberry madow wuxuu ka kooban yahay waxyaabo badan oo firfircoon ama bioactives sida Quercetin, Lupeol, Isoliquiritigenin, Formononetin, Catechol. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida Macrophage M2, JAK-STAT Signaling, Killer Cell Activation iyo Angiogenesis iyo kuwa kale. Mulberry madow waxaa lagula talinayaa Acral Melanoma marka daawaynta kansarka ee socota ay tahay Checkpoint Pdl1. Tani waa sababta oo ah Mulberry Black wuxuu wax ka beddelaa dariiqyada biochemical ee si cilmiyeysan loo soo sheegay si loo dareemo saameynta Checkpoint Pdl1.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee ku jira miro Malus (carsaanyo Apple) waa Lupeol, Isoliquiritigenin, Formononetin, Catechol, Phloretin. Maaddooyinkan firfircooni waxay wax ka qabtaan dariiqooyin kiimiko oo kala duwan sida Dendritic Cell Maturation, CD8 T-cell Activation iyo Presentation Antigen iyo kuwa kale. Malus (carsaanyo Apple) laguma talin Acral Melanoma marka daawaynta kansarka ee socota ay tahay Checkpoint Pdl1 sababtoo ah waxay wax ka beddeshaa dariiqyada biochemical ee ka dhigaya daaweynta kansarku mid adkaysi u leh ama ka jawaabi kara.

FRUIT BLACK MUBERRY ayaa lagula talinayaa MALUS (CAB APPLE) ee Acral Melanoma iyo Isbaarada daawaynta Pdl1.

Dooro Nut COMMON HAZELNUT ama XARUNTA YURUB?

Hazelnut-ka caadiga ah waxa ku jira maaddooyin badan oo firfircoon ama bioactives sida Quercetin, Lupeol, Isoliquiritigenin, Formononetin, Catechol. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida JAK-STAT Signaling, Angiogenesis, Antigen Presentation iyo T-Regulatory Cell Kala duwanaanta iyo kuwa kale. Hazelnut-ka caadiga ah ayaa lagula taliyaa Acral Melanoma marka daawaynta kansarka ee socota ay tahay Checkpoint Pdl1. Tani waa sababta oo ah Hazelnut Common waxay wax ka beddeshaa dariiqyada biochemical ee si cilmiyeysan loo soo sheegay si loo dareemo saameynta Checkpoint Pdl1.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee Chestnut Yurub waa Quercetin, Ellagic Acid, Lupeol, Isoliquiritigenin, Formononetin. Maaddooyinkan firfircooni waxay wax ka qabtaan dariiqooyin kiimikaad oo kala duwan sida Dendritic Cell Maturation, CD8 T-cell Activation iyo G-protein-kuupleed Restoring Signaling iyo kuwo kale. Chestnut Yurub laguma talinayo Acral Melanoma marka daawaynta kansarka ee socota ay tahay Checkpoint Pdl1 sababtoo ah waxay wax ka beddeshaa dariiqyada biochemical ee ka dhigaya daaweynta kansarku mid adkaysi u leh ama ka jawaabi kara.

HAZELNUT caam ah ayaa lagula talinayaa xabadka Yurub ee loogu talagalay acral melanoma iyo barta kontoroolka ee daawaynta Pdl1.

Shakhsiyaadka leh Khatarta Hidde ee Kansarka

Su'aasha ay weydiiyaan shakhsiyaadka leh khatarta hidde-sidaha ee Acral Melanoma ama taariikhda qoysku waa "Maxaan Cunnaa si ka duwan kii hore?" iyo sida ay tahay inay doortaan cuntooyinka iyo kaabista si loo maareeyo khatarta cudurka. Maadaama khatarta kansarku aanay jirin wax la qaban karo marka la eego daawaynta - go'aamada cuntooyinka iyo kaabista ayaa noqda mid muhiim ah iyo mid ka mid ah waxyaallaha aadka u yar ee la qaban karo. Dhammaan cuntooyinka dhirta ku salaysan maaha kuwo siman oo ku salaysan hidde-sideyaasha la aqoonsaday iyo saxeexa waddada Acral Melanoma - doorashooyinka cuntada iyo kaabista waa in la shakhsiyeeyo. 

Dooro CELERY STALKS ama ROMAINE LATTUCE?

Qudaarta Celery Stalks waxaa ku jira waxyaabo badan oo firfircoon ama bioactives sida Apigenin, Curcumin, Linalool, Lupeol, Lycopene. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida Kansarka Oncogenic Epigenetics, Calaamadaynta RAS-RAF, Isbaarada Wareegga Unugyada iyo Apoptosis iyo kuwa kale. Celery Stalks waxaa lagula talinayaa halista Acral Melanoma marka khatarta hidde-sidaha la xiriirta ay tahay ASXL1. Tani waa sababta oo ah Celery Stalks waxay kordhisaa dariiqyada biochemical ee ka soo horjeeda wadayaasha saxiixa.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee khudradda Romaine Lettuce waa Apigenin, Curcumin, Lupeol, Resveratrol, Protocatechuic Acid. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida P53 Signaling iyo Dayactirka DNA iyo kuwa kale. Romaine Lettuce laguma talinayo marka halista Acral Melanoma marka khatarta hidde-sidaha la xidhiidha ay tahay ASXL1 sababtoo ah waxay kordhisaa waddooyinka saxeexa ee Acral Melanoma.

STALKS-KOODA LAGU TALAGALAY OO LAGULA TALAGAY WARAR ROMAINE OO LAGU TALAGALAY ASXL1 HALISTA HIDDAHA EE KANSARKA.

Dooro Miraha NANCE ama GRAPEFRUIT?

Miraha Nance waxaa ku jira waxyaabo badan oo firfircoon ama bioactives sida Apigenin, Curcumin, Lupeol, Protocatechuic Acid, Daidzein. Maaddooyinkan firfircooni waxay wax ka qabtaan dariiqooyin kiimikaad oo kala duwan sida DNA Repair, RAS-RAF Signaling, Calaamadaynta MYC iyo Isbaarooyinka Wareegga Unugyada iyo kuwa kale. Nance waxaa lagula talinayaa halista Acral Melanoma marka khatarta hidde-sidaha la xiriirta ay tahay ASXL1. Tani waa sababta oo ah Nance waxay kordhisaa dariiqyada biochemical ee ka soo horjeeda darawaliinta saxeexa.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee ku jira canabka miraha waa Curcumin, Lupeol, Lycopene, Daidzein, Beta-sitosterol. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida DNA Repair iyo kuwo kale. Grapefruit laguma talinayo marka khatarta Acral Melanoma marka khatarta hidda-socodka la xiriirta ay tahay ASXL1 sababtoo ah waxay kordhisaa dariiqyada saxiixa ee Acral Melanoma.

FRUIT NANCE waxaa lagula talinayaa in ka badan canabkuba ASXL1 Khatarta Hiddada ee Kansarka.

Dooro lowska BUTTERNUT ama CHESTNUT?

Butternut wuxuu ka kooban yahay waxyaabo badan oo firfircoon ama bioactives sida Apigenin, Curcumin, Juglone, Lupeol, Lycopene. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida Kansarka Oncogenic Epigenetics, Calaamadaynta RAS-RAF, Calaamadaynta MYC iyo Isbaarooyinka Wareegga Unugyada iyo kuwa kale. Butternut ayaa lagula talinayaa halista Acral Melanoma marka khatarta hidde-sidaha ee la xiriirta ay tahay ASXL1. Tani waa sababta oo ah Butternut waxay kordhisaa dariiqyada biochemical ee ka soo horjeeda wadayaasha saxiixa.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee ku jira Chestnut waa Apigenin, Curcumin, Lupeol, Lycopene, Ellagic Acid. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida DNA Repair iyo kuwo kale. Chestnut laguma talinayo marka halista Acral Melanoma marka khatarta hidde-sidaha la xidhiidha ay tahay ASXL1 sababtoo ah waxay kordhisaa dariiqyada saxeexa ee Acral Melanoma.

BUTTERNUT waxa lagula talinayaa laabta si loo helo khatarta hidda-socodka ee ASXL1.

In Gabagabo

Cuntooyinka iyo Kaabayaasha la doortay ayaa ah go'aamo muhiim u ah kansarka sida Acral Melanoma. Bukaannada Acral Melanoma iyo shakhsiyaadka leh khatarta hidde-sidaha waxay had iyo jeer qabaan su'aashan: "Waa maxay cuntooyinka iyo kaabayaasha nafaqeynta ee lagu taliyay aniga iyo kuwa aan ahayn?" Waxaa jira aaminsanaan guud oo ah fikrad khaldan oo ah in dhammaan cuntooyinka dhirta ku salaysan ay faa'iido yeelan karaan ama aysan ahayn laakiin aan waxyeello lahayn. Cuntooyinka qaarkood iyo kaabisyada qaarkood waxay faragelin karaan daawaynta kansarka ama waxay kor u qaadi karaan wadayaasha dariiqyada molecular ee kansarka.

Waxaa jira noocyo kala duwan oo calaamado kansar ah sida Acral Melanoma, mid kasta oo leh hidde-sidaha burooyinka kala duwan oo leh kala duwanaansho genomic dheeraad ah oo qof kasta ah. Intaa waxaa dheer daawaynta kansar kasta iyo kiimoterabi kasta waxay leeyihiin hab wax-qabad oo gaar ah. Cunto kasta sida Kaabashka waxay ka kooban tahay noocyo kala duwan oo bioactives ah oo tirooyin kala duwan leh, kuwaas oo saameyn ku leh noocyo kala duwan oo kala duwan oo ah waddooyinka biochemical. Qeexida nafaqeynta shakhsi ahaaneed waa talooyinka cuntada ee gaarka ah ee tilmaamaya kansarka, daawaynta, genetics, qaab nololeedka iyo arrimo kale. Go'aannada shakhsiyaynta nafaqada ee kansarka waxay u baahan yihiin aqoonta bayoolajiga kansarka, sayniska cuntada iyo fahamka daaweynta kemotherabi ee kala duwan. Ugu dambeyntii marka ay jiraan isbeddel daaweyn ama genomics cusub ayaa la aqoonsaday - shakhsiyeynta nafaqeynta waxay u baahan tahay dib-u-qiimeyn.

Xalka shakhsiyaynta nafaqeynta ee addon ayaa ka dhigaysa go'aan qaadashada mid fudud oo meesha ka saaraysa dhammaan mala-awaalka ka jawaabaya su'aasha, "Waa maxay cuntooyinka aan doorto ama aan dooran Acral Melanoma?". Kooxda edbinta badan ee addon waxaa ka mid ah dhakhaatiirta kansarka, saynisyahano caafimaad, injineerada software iyo saynisyahano xogta. 

tixraacyada

1) Saamaynta Msk 2017

2) Culeyska is-beddelka ah ee buro wuxuu saadaaliyaa badbaadada ka dib daaweynta tallaalka ee noocyo badan oo kansar ah.

3) Xeer-beegtida xun-xun ee gudbiyaha calaamadaha iyo firfircoonida qoraalka-3 calaamadaynta cascade ee lupeol waxay joojisaa koritaanka waxayna keentaa apoptosis unugyada kansarka hepatocellular.

4) Saamaynta isoliquiritigenin ee unugyada kansarka ugxansidaha.

5) Saamaynta cuntada D-glucarate ee biomarkers ee caabuqa inta lagu jiro marxaladaha hore ee bilawga ah ee benzo [a] pyrene-ku-abuuray burogenesis sambabada ee jiirarka A / J.

6) Luteolin wuxuu kor u qaadaa dhimashada unugyada apoptotic iyada oo loo marayo hagaajinta Nrf2 muujinta DNA demethylase iyo isdhexgalka Nrf2 ee p53 ee unugyada kansarka mindhicirka.

7) Gallic acid waxay kicisaa dhaawaca DNA waxayna xakameysaa muujinta hidda-socodka hagaajinta DNA ee kansarka qanjirka 'prostate' ee unugyada PC-3.

https://www.ncbi.nlm.nih.gov/books/NBK559113

https://www.cancercenter.com/cancer-types/melanoma/types/acral-lentiginous-melanoma

https://www.healthline.com/health/acral-lentiginous-melanoma