Cuntooyinka Kansarka Laryngeal!

Hordhac

Cuntooyinka Kansarka Laryngeal-ka waa in loo shakhsiyeeyaa qof kasta oo waa in sidoo kale la qabsado marka daawaynta kansarka ama hidde-sidaha buradu ay isbeddelaan. Shakhsiyaynta iyo la qabsiga waa in ay tixgelisaa dhammaan maaddooyinka firfircoon ama bioactives ee ku jira cuntooyinka kala duwan marka loo eego bayooloojiyada unugyada kansarka, genetics, daawaynta, xaaladaha qaab nololeedka iyo doorbidka cuntada. Sidaa darteed iyadoo nafaqadu ay tahay mid ka mid ah go'aamada aadka muhiimka u ah bukaanka kansarka iyo qofka halista ugu jira kansarka inuu sameeyo - sida loo doorto cuntooyinka uu cuno maaha hawl fudud.

Kansarka Laryngeal miyay muhiim u tahay khudaarta, miraha, lawska, miraha la cuno?

Su'aasha nafaqeynta ee aadka u badan ee ay weydiiyaan bukaannada kansarka iyo shakhsiyaadka halista ugu jira hidde-sidaha kansarka waa - kansarka sida Kansarka Laryngeal miyay muhiim tahay cuntooyinka aan cuno iyo kuwa aanan samayn? Mise haddii aan raaco cunto ku salaysan geedka ma ku filan tahay kansarka sida Kansarka Laryngeal?

Tusaale ahaan miyay muhiim tahay haddii khudaarta Zucchini ee jaalaha ah la isticmaalo in ka badan marka loo eego Kaabashka Swamp? Miyay wax farqi ah samaynaysaa haddii miro Pitanga laga doorbido Soursop? Sidoo kale haddii xulashooyin la mid ah loo sameeyo nuts/abuurka sida Butternut oo ka sarreeya Chestnut Yurub iyo garaacyada sida Gram Bean oo ka sarreeya Lima Bean. Oo haddii waxa aan cuno ay arrintu khusayso - markaa sidee loo aqoonsan karaa cuntooyinka lagu taliyay Kansarka Laryngeal oo ma isku mid baa u tahay qof kasta oo leh isla cudurka ama khatarta hidde-sidaha?

Haa! Cuntooyinka aad cuntid waxay muhiim u yihiin Kansarka Laryngeal!

Talooyinka cuntadu waxay noqon karaan kuwo isku mid ah qof kasta oo way ka duwanaan karaan xitaa ogaanshaha isku midka ah iyo khatarta hidda-socodka.

Dhammaan cuntooyinka ( khudaarta, miraha, lawska, iniinaha, garaaca, saliidaha iwm.) iyo kaabayaasha nafaqadu waxay ka kooban yihiin wax ka badan hal walxo molecular ama bio-actives oo qiyaas iyo tiro kala duwan leh. Walax kasta oo firfircooni waxay leedahay hab u gaar ah oo wax qabad - kaas oo noqon kara firfircooni ama xannibaadda dariiqyada biochemical ee kala duwan. Cuntooyinka si fudud loo sheegay iyo kaabisyada lagu taliyay waa kuwa aan keenin korodhka wadayaasha molecular ee kansarka laakiin la yareeyo. Haddii kale cuntooyinkaas waa inaan lagu talin. Cuntooyinka waxaa ku jira maaddooyin badan oo firfircoon - markaa marka la qiimeynayo cuntooyinka iyo kaabayaasha waxaad u baahan tahay inaad tixgeliso saameynta dhammaan maaddooyinka firfircoon si wadajir ah halkii aad ka ahaan lahayd mid gaar ah.

Tusaale ahaan Pitanga waxa ku jira maaddooyinka firfircoon ee Quercetin, Apigenin, Curcumin, Lycopene, Lupeol. Soursop waxaa ku jira maaddooyinka firfircoon ee Apigenin, Curcumin, Lupeol, Emodin, Formononetin iyo kuwa kale oo suurtagal ah.

Khalad caadi ah oo la sameeyo marka la go'aaminayo oo la dooranayo cuntooyinka la cuno Kansarka Laryngeal - waa in la qiimeeyo oo kaliya maaddooyinka firfircoon ee la doortay ee ku jira cuntooyinka oo la iska indhatiro inta kale. Sababtoo ah maaddooyinka kala duwan ee firfircoon ee ku jira cuntooyinka ayaa laga yaabaa inay saameyn iska soo horjeeda ku yeeshaan darawalada kansarka - ma qaadan kartid maaddooyinka firfircoon ee cuntooyinka iyo kaabayaasha si loo gaaro go'aanka nafaqada ee Kansarka Laryngeal.

HAA – DOORASHOOYINKA CUNTADA EE KANSARKA WAXAY U TAAGAN YAHAY. GO'AANKA NAFAQADA waa in ay tixgeliyaan dhammaan walxaha firfircoon ee CUNTADA.

Xirfadaha Loo Baahan Yahay Nafaqaynta Shakhsiyaynta Kansarka Laryngeal?

Nafaqada shakhsi ahaaneed ee kansarka sida Kansarka Laryngeal wuxuu ka kooban yahay cuntooyin / cuntooyin lagu taliyey; Cuntooyinka aan lagu talin/kabka tusaale ahaan cunto karinta kuwaas oo mudnaanta siiya isticmaalka cuntooyinka lagu taliyay. Tusaale nafaqeynta gaarka ah ayaa tan lagu arki karaa link.

Go'aaminta cuntooyinka lagu taliyay iyo in kale waa mid aad u adag, oo u baahan khibrad ku saabsan bayoolajiga Kansarka Laryngeal, sayniska cuntada, genetics, biochemistry oo ay weheliso faham wanaagsan oo ku saabsan sida daawaynta kansarku u shaqeyso iyo baylahda la xidhiidha kuwaas oo daawadu ay ku joojin karto waxtarka.

Khibradda UGU YAR EE AQOONTA EE LOO BAAHAN YAHAY NAFAQADA SHAQSIYADEEDKA KANSARKA WAA: NOLOLIGA KANSARKA, CUNTADA CUNTADA, DAAWAYNTA KANSARKA IYO HIDDAHA HIDDAHA.

Astaamaha kansarka sida Kansarka Laryngeal

Dhammaan kansarrada sida Kansarka Laryngeal waxaa lagu sifeyn karaa nooc gaar ah oo ah dariiqooyin kiimikaad - dariiqooyinka saxiixa ee Kansarka Laryngeal. Dariiqooyin kiimikaad sida RAS-RAF Signaling, NFKB Signaling, PI3K-AKT-MTOR Calaamadaynta, Isbaarada Wareegga Unuggu waa qayb ka mid ah qeexida saxeexa Kansarka Laryngeal. Hidde-sideyaasha kansarku qof walba wuu ka duwanaan karaa sidaas darteed saxiixooda gaarka ah ee kansarku wuxuu noqon karaa mid gaar ah.

Daawaynta waxtarka u leh Kansarka Laryngeal waxay u baahan yihiin inay ogaadaan dariiqooyinka biochemical ee la xidhiidha saxeexa bukaanka kansarka iyo shakhsiga khatarta hidde-sidaha. Sidaa darteed daawayn kala duwan oo leh habab kala duwan oo ficil ah ayaa waxtar u leh bukaanada kala duwan. Si la mid ah iyo sababo la mid ah cuntooyinka iyo kaabista waxay u baahan yihiin in shaqsi kasta loo gaaryeelo. Sidaa darteed cuntooyinka iyo kaabista qaar ayaa lagula taliyaa Kansarka Laryngeal marka la qaadanayo daawaynta kansarka Docetaxel, iyo cuntooyinka qaarkood iyo kaabista laguma talinayo.

Ilaha sida cBioPortal iyo qaar kale oo badan ayaa bixiya xogta bukaan-socodka ee aan la magacaabin ee laga helay tijaabooyinka bukaan-socodka ee dhammaan calaamadaha kansarka. Xogtan waxay ka kooban tahay tafaasiisha daraasadda tijaabada caafimaad sida cabbirka saamiga / tirada bukaannada, kooxaha da'da, jinsiga, qowmiyadda, daawaynta, goobta burooyinka iyo isbeddellada hidde-sidaha.

TP53, NOTCH1, CDKN2A, KMT2D iyo NFE2L2 waa hiddo-wadaha ugu sarreeya ee la soo sheegay ee Kansarka Laryngeal. TP53 ayaa lagu soo warramey 40.7 % bukaanada matala dhamaan tijaabooyinka caafimaad. Iyo NOTCH1 ayaa lagu soo warramey 18.5 %. Isku darka xogta bukaanka ee dadweynaha waxay daboolaysaa da'da 52 ilaa 67. 84.7 % xogta bukaanka waxaa loo aqoonsaday inay yihiin rag. Bayolojiga Kansarka Laryngeal oo ay weheliso hidde-sideyaasha la soo sheegay ayaa si wada jir ah u qeexaya dariiqooyinka biochemical ee saxeexa dadweynaha ee kansarkan. Haddii genetics-ka burada kansarka shakhsi ahaaneed ama hiddo-wadaha ka qaybqaata khatarta sidoo kale waa la yaqaan markaa waa in sidoo kale loo isticmaalo shakhsiyaynta nafaqada.

Dookhyada nafaqeynta waa in ay iswaafaqaan shaqsi walba saxiixiisa.

Cuntada iyo Kaabayaasha Kansarka Laryngeal

Bukaanka Kansarka

Bukaanjiifka kansarka ee ku jira daawaynta ama daryeelka palliative waxay u baahan yihiin inay go'aan ka gaadhaan cuntada iyo kaabista - kaloriinta cuntada ee loo baahan yahay, maaraynta waxyeellooyin kasta oo daawaynta iyo sidoo kale hagaajinta maaraynta kansarka. Dhammaan cuntooyinka dhirta ku salaysan maaha kuwo siman oo doorashada iyo kala horraysiinta cuntooyinka kuwaas oo shakhsi ahaan loo habeeyey oo loo habeeyey daawaynta kansarka ee socota waa muhiim oo dhib badan. Waa kuwan tusaalayaal siinaya tilmaamo lagu samaynayo go'aannada nafaqada.

Dooro ZUCCHINI JALE ah oo khudaar ah ama Kaabashka SWAMP?

Zucchini jaalaha ah khudradda waxaa ku jira waxyaabo badan oo firfircoon ama bioactives sida Apigenin, Curcumin, Lupeol, Formononetin, Daidzein. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida Hypoxia, Signaling NFKB iyo PI3K-AKT-MTOR Signaling iyo kuwa kale. Zucchini jaale ah ayaa lagula talinayaa Kansarka Laryngeal marka daawaynta kansarka ee socota ay tahay Docetaxel. Tani waa sababta oo ah Zucchini jaalaha ah waxay wax ka beddeshaa dariiqyada biochemical ee si cilmiyeysan loo soo sheegay si loo dareemo saameynta Docetaxel.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee ku jira Kaabashka Swamp khudradda waa Curcumin, Lycopene, Lupeol, Formononetin, Daidzein. Maaddooyinkan firfircooni waxay wax ka qabtaan dariiqooyin kiimikaad oo kala duwan sida Jawaab celinta Cadaadiska Kulaylka iyo kuwa kale. Kaabashka Swamp laguma talinayo Kansarka Laryngeal marka daawaynta kansarka ee socota ay tahay Docetaxel sababtoo ah waxay wax ka beddeshaa dariiqyada biochemical ee ka dhigaya daaweynta kansarku mid adkaysi u leh ama aan ka jawaabin.

ZUCCHINI JALE LUQADA AH ayaa lagula talinayaa Kaabashka SWAMP ee Kansarka Laryngeal iyo daawaynta Docetaxel.

Dooro midhaha SOURSOP ama PITANGA?

Miraha Soursop waxay ka kooban yihiin waxyaabo badan oo firfircoon ama bioactives sida Apigenin, Curcumin, Lupeol, Emodin, Formononetin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida MAPK Signaling, Signaling MYC, Signaling NFKB iyo PI3K-AKT-MTOR Signaling iyo kuwa kale. Soursop waxaa lagula talinayaa Kansarka Laryngeal marka daawaynta kansarka ee socota ay tahay Docetaxel. Tani waa sababta oo ah Soursop waxay wax ka beddeshaa dariiqyada biochemical ee si cilmiyeysan loo soo sheegay si loo dareemo saameynta Docetaxel.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee ku jira miro Pitanga waa Quercetin, Apigenin, Curcumin, Lycopene, Lupeol. Maaddooyinkan firfircooni waxay wax ka qabtaan dariiqooyin kiimikaad oo kala duwan sida Jawaabta Cadaadiska Kulaylka, Calaamadaynta TGFB iyo Calaamadaynta NFKB iyo kuwa kale. Pitanga laguma talinayo Kansarka Laryngeal marka daawaynta kansarka ee socota ay tahay Docetaxel sababtoo ah waxay wax ka beddeshaa dariiqyada biochemical ee ka dhigaya daaweynta kansarku mid adkaysi u leh ama aan ka jawaabin.

SOURSOP FRUIT ayaa lagula talinayaa PITANGA Kansarka Laryngeal iyo daawaynta Docetaxel.

Dooro BUTTERNUT lowska ama XARUNTA YURUB?

Butternut wuxuu ka kooban yahay waxyaabo badan oo firfircoon ama bioactives sida Apigenin, Curcumin, Lycopene, Lupeol, Formononetin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida MAPK Signaling, Signaling TGFB, NFKB Signaling iyo PI3K-AKT-MTOR Signaling iyo kuwa kale. Butternut ayaa lagula talinayaa Kansarka Laryngeal marka daawaynta kansarka ee socota ay tahay Docetaxel. Tani waa sababta oo ah Butternut waxay wax ka beddeshaa dariiqyada biochemical ee si cilmiyeysan loo soo sheegay si loo dareemo saameynta Docetaxel.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee ku jira Chestnut Yurub waa Quercetin, Apigenin, Curcumin, Ellagic Acid, Lupeol. Maaddooyinkan firfircooni waxay wax ka qabtaan dariiqooyin kiimikaad oo kala duwan sida Jawaab celinta Cadaadiska Kulaylka iyo kuwa kale. Chestnut Yurub laguma talinayo Kansarka Laryngeal marka daawaynta kansarka ee socota ay tahay Docetaxel sababtoo ah waxay wax ka beddeshaa dariiqyada biochemical ee ka dhigaya daaweynta kansarku mid adkaysi u leh ama ka jawaabi kara.

BUTTERNUT ayaa lagula talinayaa laabta Yurub ee Kansarka Laryngeal iyo daawaynta Docetaxel.

Shakhsiyaadka leh Khatarta Hidde ee Kansarka

Su'aasha ay weydiiyaan shakhsiyaadka leh khatarta hidde-sidaha Kansarka Laryngeal ama taariikhda qoyska waa "Maxaan Cunnaa si ka duwan kii hore?" iyo sida ay tahay inay doortaan cuntooyinka iyo kaabista si loo maareeyo khatarta cudurka. Maadaama khatarta kansarku aanay jirin wax la qaban karo marka la eego daawaynta - go'aamada cuntooyinka iyo kaabista ayaa noqda mid muhiim ah iyo mid ka mid ah waxyaallaha aadka u yar ee la qaban karo. Dhammaan cuntooyinka dhirta ku salaysan maaha kuwo siman oo ku salaysan hidde-sidaha la aqoonsaday iyo saxeexa dariiqa - doorashooyinka cuntada iyo kaabista waa in la shakhsiyeeyo.

Dooro CALABASH khudaar ah ama HEAD FAARAN?

Calabash khudradda waxaa ku jira waxyaabo badan oo firfircoon ama bioactives sida Apigenin, Curcumin, Lupeol, Daidzein, Beta-sitosterol. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida MAPK Signaling, Oxidative Stress, Signaling Cell Stem iyo PI3K-AKT-MTOR Signaling iyo kuwa kale. Calabash waxaa lagula talinayaa halista Kansarka Laryngeal marka khatarta hidde-sidaha la xiriirta ay tahay CDKN2A. Tani waa sababta oo ah Calabash waxay kordhisaa dariiqyada biochemical ee ka soo horjeeda wadayaasha saxeexa.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee ku jira Arrowhead khudradda waa Apigenin, Curcumin, Lupeol, Daidzein, Beta-sitosterol. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida isbaarada wareegga unugyada iyo walbahaarka Oxidative iyo kuwa kale. Arrowhead laguma talinayo marka halista Kansarka Laryngeal marka khatarta hidde-sidaha la xidhiidha ay tahay CDKN2A sababtoo ah waxay kordhisaa dariiqyada saxeexa ee isaga.

CABAASHKA khudaarta ah waxaa lagula talinayaa in lagu dul taago falaarta si loo helo khatarta hidda-socodka CDKN2A ee kansarka.

Dooro Miraha NANCE ama CABKA MUSCADINE?

Miraha Nance waxaa ku jira waxyaabo badan oo firfircoon ama bioactives sida Apigenin, Curcumin, Lupeol, Daidzein, Beta-sitosterol. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida MAPK Signaling, Oxidative Stress, Signaling Cell Stem iyo PI3K-AKT-MTOR Signaling iyo kuwa kale. Nance waxaa lagula taliyaa halista Kansarka Laryngeal marka khatarta hidde-sidaha la xiriirta ay tahay CDKN2A. Tani waa sababta oo ah Nance waxay kordhisaa dariiqyada biochemical ee ka soo horjeeda darawaliinta saxeexa.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee ku jira Canabka Muscadine ee miraha waa Apigenin, Curcumin, Lupeol, Ellagic Acid, Daidzein. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida isbaarada wareegga unugyada iyo calaamadaynta unugga stem iyo kuwa kale. Canabka Muscadine laguma talinayo marka halista Kansarka Laryngeal marka khatarta hidde-sidaha la xiriirta ay tahay CDKN2A sababtoo ah waxay kordhisaa dariiqooyinka saxiixa.

FRUIT NANCE waxaa lagula talinayaa canabka muruqa ee loogu talagalay halista hidda-socodka CDKN2A ee kansarka.

Dooro Nut COMMON HAZELNUT ama FLAXSEED?

Hazelnut-ka caadiga ah waxa ku jira maaddooyin badan oo firfircoon ama bioactives sida Curcumin, Lupeol, Daidzein, Quercetin, Beta-sitosterol. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida MAPK Signaling, PI3K-AKT-MTOR Signaling, Signaling Cell Stem iyo Oxidative Stress iyo kuwa kale. Hazelnut-ka caadiga ah waxa lagula taliyaa halista Kansarka Laryngeal marka khatarta hidde-sidaha la xidhiidha ay tahay CDKN2A. Tani waa sababta oo ah Hazelnut Common waxay kordhisaa dariiqyada biochemical ee ka soo horjeeda wadayaasha saxeexa.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee ku jira Flaxseed waa Apigenin, Curcumin, Lupeol, Daidzein, Beta-sitosterol. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida MAPK Signaling, PI3K-AKT-MTOR Signaling iyo Oxidative Stress iyo kuwa kale. Flaxseed laguma talinayo marka halista Kansarka Laryngeal marka khatarta hidde-sidaha ay tahay CDKN2A sababtoo ah waxay kordhisaa dariiqyada saxiixa.

HAZELNUT caam ah ayaa lagula taliyaa FLAXSEEDKA HALISTA hidda-socodka CDKN2A ee kansarka.

In Gabagabo

Cuntooyinka iyo Kaabayaasha la doortay ayaa ah go'aamo muhiim u ah kansarka sida Kansarka Laryngeal. Bukaannada Kansarka Laryngeal-ka iyo shakhsiyaadka leh khatarta hidde-sidaha waxay had iyo jeer qabaan su'aashan: "Waa maxay cuntooyinka iyo nafaqooyinka nafaqada ee lagu taliyey aniga iyo kuwa aan ahayn?" Waxaa jira aaminsanaan guud oo ah fikrad khaldan oo ah in dhammaan cuntooyinka dhirta ku salaysan ay faa'iido yeelan karaan ama aysan ahayn laakiin aan waxyeello lahayn. Cuntooyinka qaarkood iyo kaabisyada qaarkood waxay faragelin karaan daawaynta kansarka ama waxay kor u qaadi karaan wadayaasha dariiqyada molecular ee kansarka.

Waxaa jira noocyo kala duwan oo tilmaamayaasha kansarka sida Kansarka Laryngeal, mid kasta oo leh hidde-sidaha burooyinka kala duwan oo leh kala duwanaansho genomic oo dheeraad ah oo qof kasta ah. Intaa waxaa dheer daawaynta kansar kasta iyo kiimoterabi kasta waxay leeyihiin hab wax-qabad oo gaar ah. Cunto kasta sida Zucchini jaalaha ah waxay ka kooban tahay tirooyin kala duwan oo bioactives ah oo tirooyin kala duwan leh, kuwaas oo saameyn ku leh noocyo kala duwan oo kala duwan oo ah dariiqyada biochemical. Qeexida nafaqeynta shakhsi ahaaneed waa talooyinka cunto ee gaarka ah ee tilmaamaya kansarka, daawaynta, genetics, qaab nololeedka iyo arrimo kale. Go'aannada shakhsiyaynta nafaqada ee kansarka waxay u baahan yihiin aqoonta bayoolajiga kansarka, sayniska cuntada iyo fahamka daaweynta kemotherabi ee kala duwan. Ugu dambeyntii marka ay jiraan isbeddel daaweyn ama genomics cusub ayaa la aqoonsaday - shakhsiyeynta nafaqeynta waxay u baahan tahay dib-u-qiimeyn.

Xalka shakhsiyaynta nafaqeynta ee addon ayaa ka dhigaysa go'aan qaadashada mid fudud oo meesha ka saaraysa dhammaan mala-awaalka ka jawaabaya su'aasha, "Cunto noocee ah ayaan dooran karaa ama ma dooran karaa Kansarka Laryngeal?". Kooxda edbinta badan ee addon waxaa ka mid ah dhakhaatiirta kansarka, saynisyahano caafimaad, injineerada software iyo saynisyahano xogta.

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