Tilmaamaha
Quercetin waa flavonoid dabiici ah oo ku jira cuntooyinka kala duwan sida miraha iyo khudaarta midabka leh waxayna leedahay faa'iidooyin caafimaad oo badan sababtoo ah antioxidant xoog leh, anti-kansarka, bararka, fayraska iyo guryaha bakteeriyada. Daraasado kala duwan oo tijaabo ah iyo xayawaanno ayaa muujiyay faa'iidooyinka daweynta ee suurtogalka ah ee quercetin (laga helo cuntooyinka / kaabiska) ee noocyada kansarka gaarka ah sida pankreatka, naaska, ugxan-sidaha, beerka, glioblastoma, prostate iyo kansarka sambabada, iyo sidoo kale hagaajinta waxtarka daaweynta kemotherabi gaar ah iyo kale kansarka daawaynta Tijaabooyin caafimaad oo waaweyn ayaa loo baahan yahay in la sameeyo si loo xaqiijiyo faa'iidooyinkan aadanaha. Sidoo kale, isticmaalka xad-dhaafka ah ee quercetin waxay u horseedi kartaa waxyeellooyin sida shaqada tayroodh.
Waa maxay Quercetin?
Quercetin waa flavonoid dabiici ah oo laga helo cuntooyin badan oo nafaqo leh oo ay ka mid yihiin:
- Midhaha midabka leh sida tufaaxa, canabka iyo berry
- Basasha cas
- Teas
- berry
- khamri Red
- Cagaarka cagaaran
- Tamaandho
- broccoli
Waxay leedahay antioxidant xoog leh, anti-bararka, fayraska iyo bakteeriyada.
Faa'iidooyinka Caafimaadka ee Quercetin
Ahaanshaha antioxidant xoog leh, quercetin iyo quercetin cuntooyin hodan ah ayaa loo tixgeliyaa inay leeyihiin faa'iidooyin caafimaad oo badan. Qaar ka mid ah faa'iidooyinka caafimaad ee quercetin waxaa ka mid ah:
- Waxay yareyn kartaa cudurada wadnaha
- Waxaa laga yaabaa inuu yareeyo bararka
- Waxay yareyn kartaa calaamadaha gabowga
- Waxay yareyn kartaa halista caabuqyada neef -mareenka iyo caloosha
- Waxaa laga yaabaa inuu yareeyo cadaadiska dhiigga
- Waxay yareyn kartaa xasaasiyadda
Saameynada dhinaca Quercetin
Kuwa soo socda ayaa ah qaar ka mid ah saameynaha guud ee quercetin marka afka laga cuno:
- Kabuubyo gacmaha iyo lugaha
- Madax
Maamulka xididka ee qadar aad u sarreeya oo quercetin ah ayaa laga yaabaa inuu dadka qaarkood u yeesho waxyeelo sida:
- Biyo raacid iyo dhidid
- Lalabbo iyo matag
- Neefsashada adag
- Waxyeello kelyaha ah
Waxyeellada kale ee suurtogalka ah ee la xiriirta qaadashada xad-dhaafka ah ee quercetin ayaa ah inay faragelin karto shaqada tayroodh. Marka laga reebo waxyeellooyinka sida cilladda tayroodh, qaadashada quercetin ayaa sidoo kale laga yaabaa inay ka sii darto xaaladaha kuwa qaba dhibaatooyinka kelyaha.
Guryaha Ka-hortagga Kansarka ee Quercetin
Quercetin-ka flavonoid wuxuu u muuqdaa inuu yahay wakiil ballan-qaad ah oo ka-hortagga kansarka oo ku saleysan natiijooyinka laga helay dhowr shaybaar iyo moodallo xayawaan oo hore iyo dhowr daraasadood oo caafimaad iyo indho-indheyn ah. Hoos waxaa ah tusaalooyinka qaar ka mid ah daraasaddan oo muujinaya faa'iidooyinka ka-hortagga kansarka ee quercetin.
Cuntooyinka la Cuno Ka Dib Baaritaanka Kansarka!
Ma jiraan laba kansar oo isku mid ah. Ka gudub tilmaamaha guud ee nafaqada ee qof walba oo samee go'aanno shaqsiyeed oo ku saabsan cuntada iyo kaabayaasha si kalsooni leh.
Saamaynta Isticmaalka Quercetin oo ay weheliyaan Kaabisyo Kale ama Daaweynta Kansarka
Quercetin oo ay weheliso Curcumin ayaa laga yaabaa inay yareyso Adenomas ee Bukaanka qaba Qoyska Adenomatous Polyposis - Daraasadda Caafimaadka
Daraasad caafimaad oo yar oo ay sameeyeen cilmi -baareyaasha ka socda Cleveland Clinic ee Florida, Mareykanka ayaa qiimeysay waxtarka isku -darka isku -darka cuntada curcumin iyo quercetin si loo yareeyo adenomas 5 bukaan oo leh polyposis Familial adenomatous polyposis, xaalad la iska dhaxlo halkaas oo tiro ka mid ah burooyinka hore u soo baxaan xiidanka ama malawadka, taas oo kordhineysa fursadaha kansarka mindhicirka. Daraasadu waxay ogaatay in tirada iyo cabirka burooyinka ay hoos u dhacday dhammaan bukaanada leh celcelis boqolkiiba hoos u dhac 60.4% iyo 50.9%, siday u kala horreeyaan, ka dib 6 bilood oo lagu daaweeyay curcumin iyo quercetin. (Marcia Cruz-Correa et al, Clin Gastroenterol Hepatol., 2006)
Quercetin ayaa laga yaabaa inay wanaajiso Waxtarka Temozolomide ee Ka-hortagga Unugyada Glioblastoma-Daraasadda Tijaabada
Daraasad shaybaar oo ay sameeyeen cilmi -baarayaashu waxay sameysteen Isbitaalka Caafimaadka Dhaqanka Shiinaha ee Changshu iyo Isbitaalka Labaad ee Jaamacadda Soochow ee Shiinaha ayaa lagu ogaaday in isticmaalka quercetin oo ay weheliso temozolomide, oo ah daaweynta daaweynta kiimoteraabiga ee daaweynta burooyinka maskaxda, waxay si weyn u wanaajisay saameynta xannibaadda Temozolomide ee glioblastoma bini’aadamka/unugyada kansarka maskaxda waxayna cabudhiyeen badbaadada unugyada glioblastoma. (Dong-Ping Sang et al, Acta Pharmacol Sin., 2014)
Quercetin waxaa laga yaabaa inay hagaajiso saameynta ka-hortagga kansarka ee Doxorubicin ee Unugyada Kansarka Beerka-Daraasad Tijaabo ah
Daraasad kale oo shaybaar ah oo ay sameeyeen cilmi-baarayaasha ka socda Jaamacadda Zhejiang ee Shiinaha ayaa iftiimisay in isticmaalka quercetin ay kor u qaadi karto saameynta kansarka ka-hortagga kansarka dawaynta doxorubicin ee unugyada kansarka beerka iyadoo la ilaalinayo unugyada beerka ee caadiga ah. (Guanyu Wang et al, PLoS One., 2012)
Quercetin oo ay weheliso Cisplatin Chemotherapy ayaa laga yaabaa inay kor u qaaddo Apoptosis/Dhimashada Unug ee Kansarka Afka - Daraasad Tijaabo ah
Daraasad ay sameeyeen cilmi-baarayaasha Xarunta Guangdong ee Xakamaynta iyo Ka-hortagga Cudurrada, Jaamacadda Sun Yat-sen iyo Machadka Sayniska Deegaanka ee Koonfurta Shiinaha-Guangzhou ee Shiinaha, waxay qiimeeyeen saameynta adeegsiga quercetin oo ay weheliso kiimiko lagu daaweeyo cisplatin Khadadka Unugga Carcinoma Cell (OSCCs) iyo sidoo kale jiirarka ku dhaca kansarka afka. Daraasadu waxay ogaatay in isku -darka quercetin iyo cisplatin ay kor u qaadeen dhimashada unugyada/apoptosis ee unugyada kansarka afka ee aadanaha sidoo kale waxay horjoogsadeen koritaanka kansarka ee jiirarka, taasoo soo jeedineysa kartida daaweynta ee quercetin iyo cisplatin isku -darka kansarka afka. (Xin Li et al, J Kansarka., 2019)
Isticmaalka Quercetin ee Kansarka Ovarian Diidmada Cisplatin Chemotherapy ayaa laga yaabaa inay faa'iido leedahay - Daraasadda Caafimaadka
Marxalad yar oo 1 tijaabo caafimaad ah oo ay sameeyeen cilmi-baarayaasha Jaamacadda Birmingham, UK, bukaan qaba kansarka ugxan-sidaha oo aan ka jawaabin daaweynta cisplatin ayaa la siiyay laba kooras oo quercetin ah, oo dhajiyay qadarka borotiinka CA 125 (kansarka antigen 125 - loo isticmaalo calaamad u ah kansarka ugxan-sidaha) ee dhiigga ayaa si weyn hoos ugu dhacay 295 ilaa 55 unug/ml. (DR Ferry iyo al, Clin Cancer Res. 1996)
Quercetin Supplement oo ay weheliso Resveratrol ayaa laga yaabaa inay ka faa'iideysato maareynta Kansarka Qanjidh -ka iyo Kansarka mindhicirka - Daraasadda Hore
Daraasad ay sameeyeen cilmi -baarayaasha Jaamacadda Wisconsin iyo William S. Middleton VA Medical Center ee Wisconsin ee Maraykanka oo ku jirta jiir (transgenic adenocarcinoma of the prostate -prostam -TRAMP) oo si dhow ugu eekaanaya jiritaanka kansarka qanjidhka dadka, ayaa la helay in isku-darka quercetin iyo kaabayaasha resveratrol, laba antioxidants oo si aad ah looga helo canab, ay leeyihiin faa'iidooyin ka-hortagga kansarka ee nooca jiirka kansarka qanjirka 'prostate'. (Chandra K Singh et al, Kansarrada (Basel)., 2020)
Daraasad kale oo ay sameeyeen cilmi -baarayaasha Jaamacadda Texas A&M, ee Mareykanka ayaa lagu ogaaday in isku darka Resveratrol iyo quercetin ayaa laga yaabaa inay yeeshaan wax ka -hortagga kansarka ee unugyada kansarka mindhicirka. (Armando Del Follo-Martinez et al, Kansarka Nutr., 2013)
Quercetin ayaa laga yaabaa inay wanaajiso waxtarka daweynta ee daaweynta Fluorouracil ee Kansarka Beerka - Daraasad tijaabo ah
Daraasad shaybaar oo ay sameysay Jaamacadda Kurume, ee Japan ayaa lagu ogaaday in daaweynta isku dhafan ee quercetin iyo fluorouracil (5-FU) ay horseedi karto saameyn ka-hortag ah oo dheeri ah ama isku-dhafan oo ku aaddan faafidda unugyada kansarka beerka. (Toru Hisaka et al, Resicancer Res. 2020)
Isticmaalka Quercetin iyo Halista Kansarka
Qaadashada Quercetin waxay yareyn kartaa Khatarta Kansarka Gastric-ka ee Aan Kaadhka ahayn
Baarayaasha Karolinska Institutet ee Iswiidhan waxay falanqeeyeen xog laga helay daraasad ballaaran oo ku saleysan dadweynaha Iswiidhan oo ku lug leh 505 kiis oo kansarka caloosha ah iyo 1116 kontaroolo si loo qiimeeyo xiriirka ka dhexeeya quercetin iyo halista noocyada kala duwan ee kansarka caloosha sida kaadiya iyo noocyada hoose ee aan ahayn cardia ee kansarka caloosha . Daraasaddu waxay ogaatay in qaadashada quercetin ee cuntada oo aad u sarreysa ay si weyn hoos ugu dhigtay halista adenocarcinoma gastric noncardia, gaar ahaan dumarka sigaarka cabba. (AM Ekström et al, Ann Oncol., 2011)
Qaadashada quercetin cuntooyinka hodanka ku ah ayaa markaa laga yaabaa inay faa'iido u leedahay yareynta halista kansarrada sida kansarka caloosha.
Daraasado Tijaabo ah oo ku Saabsan Awoodda Ka-hortagga Kansarka ee Quercetin
Daraasado badan oo shaybaadh ayaa ay sameeyeen cilmi-baarayaal ka kala yimid meelo kala duwan oo adduunka ah si ay u ogaadaan in cuntooyinka hodanka ah ee quercetin ay leeyihiin saameyn liddi ku ah kansarka noocyada kala duwan. Kansarka. Hoos waxaa ku yaal tusaalayaal ka mid ah daraasadihii shaybaadhka ee dhawaanahan ama daraasadihii hore ee daaweynta kuwaas oo qiimeeyay awoodda ka hortagga kansarka ee Quercetin.
Kansarka Beerka: Daraasad ay sameeyeen cilmi -baarayaasha Jaamacadda Kurume ee Japan ayaa iftiimisay in quercetin laga yaabo inay hor istaagto faafitaanka unugyada kansarka beerka iyadoo kicineysa apoptosis/dhimashada unugyada iyo sidoo kale xiritaanka wareegga unugyada. (Toru Hisaka et al, Resicancer Res., 2020)
Kansarka Sambabka: Daraasad ay samaysay Jaamacadda Hubei University of Medicine, Shiinaha ayaa iftiimisay in quercetin laga yaabo inay hor istaagto faafitaanka iyo kansarka ee khadadka unugyada kansarka sanbabada ee Unug-yar. (Yan Dong et al, Med Sci Monit, 2020)
Kansarka Qanjirka 'prostate': Daraasad ay sameeyeen cilmi-baarayaasha Jaamacadda Madras ee Hindiya iyo Jaamacadda Pukyong National University ee Kuuriyada Koonfureed ayaa lagu ogaaday in quercetin ay yareyn karto badbaadada unugyada kansarka qanjirka 'prostate' ee moodooyinka xoolaha ee hore, waxayna sidoo kale horjoogsan kartaa borotiinka faafa iyo ka hortagga apoptotic, oo tilmaamaya faa'iidooyinka suurtagalka ah daawooyinka quercetin ee ka hortagga halista kansarka qanjirka 'prostate'. (G Sharmila et al, Clin Nutr., 2014)
Kansarka Ovarian: Daraasad ay sameeyeen cilmi -baarayaasha Jaamacadda Madras, India ayaa iftiimisay in Quercetin ay awood u leedahay inay hor istaagto koritaanka unugyada kansarka ugxan -sidaha. (Dhanaraj Teekaraman et al, Chem Biol Interact., 2019)
Kansarka Naasaha: Daraasad shaybaar oo ay sameeyeen cilmi -baarayaasha Jaamacadda Madras ee Hindiya, waxay iftiimiyeen in adeegsiga Quercetin ay gacan ka geysan karto soo -kicinta Apoptosis ama Unugga unugyada Kansarka Naasaha. (Santhalakshmi Ranganathan et al, PLoS One., 2015)
Kansarka Pankreatic: Baarayaasha ka socda Iskuulka Daawada David Geffen ee UCLA, Mareykanka ayaa qiimeeyay wax ku oolnimada maamulka afka ee quercetin ee nooca jiirka kansarka ganaca waxayna ogaadeen in quercetin ay awood u leedahay inay hor istaagto koritaanka burooyinka beeryarada ee qaabka jiirka. (Eliane Angst et al, Pancreas., 2013)
Ugu Dambeyn
Daraasado caafimaad oo kala duwan iyo kuwo shaybaadh ayaa muujiyay suurtagalnimada/faa'iidooyinka suurtagalka ah ee cuntooyinka hodanka ku ah quercetin iyo kaabisyada daaweynta gaarka ah. kansarka noocyada sida ganaca, naaska, ugxan-sidaha, beerka, glioblastoma, qanjirka 'prostate' iyo kansarka sanbabada, iyo sidoo kale hagaajinta waxtarka daaweynta ee chemotherapies gaar ah iyo daaweynta kale ee kansarka. Tijaabooyin caafimaad oo waaweyn ayaa la sameeyaa si loo xaqiijiyo faa'iidooyinka ka hortagga kansarka ee quercetin ee aadanaha.
Quercetin waxay leedahay antioxidant xoog leh, anti-kansarka, ka-hortagga bararka, fayraska fayraska iyo bakteeriyada. Faa'iidooyinka caafimaad ee kala duwan ee quercetin ayaa la heli karaa iyada oo lagu daro cuntooyin kala duwan sida miraha iyo khudaarta midabada leh iyo nafaqo leh oo qayb ka ah cuntada. Dheeraadka Quercetin waxaa badanaa lagu daraa xeryahooda kale ee noolaha sida Vitamin C ama Bromelain si loo hagaajiyo nuugista iyo awoodda. Si kastaba ha noqotee, qaadashada xad -dhaafka ah ee quercetin waxay u horseedi kartaa saameyno badan oo ay ka mid tahay faragelinta shaqada tayroodh ee habboon. Iska ilaali inaad isticmaasho quercetin supplements iyada oo aan la hagayn dhakhaatiirtaada daryeelka caafimaadka si aad uga fogaato waxyeellooyinka sida cillad tayroodh iyo isdhexgalka daawaynta socota.
Cuntada aad cunayso iyo waxyaalaha dheeraadka ah ee aad qaadato ayaa ah go'aanka aad gaadho. Go'aankaagu waa inuu ku jiraa tixgelinta isbeddellada hidda -wadaha kansarka, kansarka, daaweynta joogtada ah iyo kaabisyada, wixii xasaasiyad ah, macluumaadka hab -nololeedka, miisaanka, dhererka iyo caadooyinka.
Qorshaynta nafaqada kansarka ee addon kuma salaysna raadinta internetka. Waxay si otomaatig ah kuu siineysaa go'aanka adiga oo ku saleynaya sayniska molikalikada oo ay hirgeliyeen saynisyahannadeenna iyo injineerada software -ka. Iyadoo aan loo eegin haddii aad danaynayso inaad fahanto waddooyinka kelli -yaqaanka ee biochemical -ka hoose iyo haddii kale - qorshaynta nafaqada ee kansarka fahamka ayaa loo baahan yahay.
Hadda ku bilow qorshaynta nafaqada adiga oo ka jawaabaya su'aalaha ku saabsan magaca kansarka, isbeddellada hidda -socodka, daaweynta joogtada ah iyo kaabisyada, wixii xasaasiyad ah, caadooyin, hab -nololeed, kooxda da'da iyo jinsiga.
Nafaqada gaarka ah ee kansarka!
Kansarku wuu is beddelaa waqti ka dib. Habbee oo wax ka beddel nafaqadaada iyadoo lagu salaynayo calaamadda kansarka, daawaynta, qaab nololeedka, dookhyada cuntada, xasaasiyadda iyo arrimo kale.
Bukaannada kansarka badanaa waa inay la macaamilaan waxyaabo kala duwan waxyeellooyinka daaweynta kemotherabi kaas oo saameeya tayadooda nololeed isla markaana fiiriya daweynta kale ee kansarka. Qaadashada nafaqada saxda ah iyo kaabisyada ku saleysan tixgelinta cilmiga (iska ilaalinta mala-awaal iyo xulasho aan kala sooc lahayn) ayaa ah daaweynta ugu fiican ee dabiiciga ah ee kansarka iyo daaweynta la xiriirta dhibaatooyinka soo raaca.