Cuntooyinka loogu talagalay Mastocytosis habaysan!

Hordhac

Cuntooyinka loogu talagalay mastocytosis nadaamsan waa in loo shakhsiyeeyaa shaqsi kasta waana in sidoo kale la qabsado marka daaweynta kansarka ama hidde-sidaha buradu ay isbeddelaan. Shakhsiyaynta iyo la qabsiga waa in ay tixgelisaa dhammaan maaddooyinka firfircoon ama bioactives ee ku jira cuntooyinka kala duwan marka loo eego bayooloojiyada unugyada kansarka, genetics, daawaynta, xaaladaha qaab nololeedka iyo doorbidka cuntada. Sidaa darteed iyadoo nafaqadu ay tahay mid ka mid ah go'aamada aadka muhiimka u ah bukaanka kansarka iyo qofka halista ugu jira kansarka inuu sameeyo - sida loo doorto cuntooyinka uu cuno maaha hawl fudud.

Mastocytosis systemic miyay muhiim u tahay khudaarta, miraha, lawska, iniinaha qofku cuno?

Su'aasha nafaqeynta ee aadka u badan ee ay weydiiyaan bukaannada kansarka iyo shakhsiyaadka halista ugu jira hidde-sidaha kansarka waa - kansarrada sida Systemic Mastocytosis miyay muhiim u tahay cuntooyinka aan cuno iyo kuwa aanan samayn? Mise haddii aan raaco cunto ku salaysan geedka ma ku filan tahay kansarka sida Systemic Mastocytosis?

Tusaale ahaan miyay muhiim tahay haddii khudaarta Brussel sprouts la isticmaalo in ka badan marka loo eego Turnip? Miyay wax farqi ah samaynaysaa haddii midho berde laga door bidayo Rabbiteye Blueberry? Sidoo kale haddii xulashooyin la mid ah loo sameeyo nuts/abuurka sida Black Walnut oo ka sarreeya Chestnut iyo garaacyada sida Chickpea oo ka sarreeya Catjang Pea. Oo haddii waxa aan cunaa ay arrintu khusayso - markaa sidee qofku u aqoonsan karaa cuntooyinka lagu taliyey ee Mastocytosis System oo ma isku mid bay u tahay qof kasta oo leh calaamad isku mid ah ama khatarta hidda-socodka?

Haa! Cuntooyinka aad cuntid waxay muhiim u yihiin Mastocytosis System!

Talooyinka cuntadu waxay noqon karaan kuwo isku mid ah qof kasta oo way ka duwanaan karaan xitaa ogaanshaha isku midka ah iyo khatarta hidda-socodka.

Dhammaan cuntooyinka ( khudaarta, miraha, lawska, iniinaha, garaaca, saliidaha iwm.) iyo kaabayaasha nafaqadu waxay ka kooban yihiin wax ka badan hal walxo molecular ama bio-actives oo qiyaas iyo tiro kala duwan leh. Walax kasta oo firfircooni waxay leedahay hab u gaar ah oo wax qabad - kaas oo noqon kara firfircooni ama xannibaadda dariiqyada biochemical ee kala duwan. Cuntooyinka si fudud loo sheegay iyo kaabisyada lagu taliyay waa kuwa aan keenin korodhka wadayaasha molecular ee kansarka laakiin la yareeyo. Haddii kale cuntooyinkaas waa inaan lagu talin. Cuntooyinka waxaa ku jira maaddooyin badan oo firfircoon - markaa marka la qiimeynayo cuntooyinka iyo kaabayaasha waxaad u baahan tahay inaad tixgeliso saameynta dhammaan maaddooyinka firfircoon si wadajir ah halkii aad ka ahaan lahayd mid gaar ah.

Tusaale ahaan berdaha waxa ku jira maaddooyin firfircoon oo isoliquiritigenin, Quercetin, Kaempferol, Taxifolin, Curcumin. Rabbiteye blueberry waxaa ku jira maaddooyinka firfircoon ee Quercetin, Linalool, Geraniol, Gallic Acid, Ferulic Acid iyo kuwo kale oo suurtagal ah.

Khalad caadi ah oo la sameeyo marka la go'aaminayo oo la dooranayo cuntooyinka la cuno ee nidaamka Mastocytosis - waa in la qiimeeyo oo kaliya maaddooyinka firfircoon ee la doortay ee ku jira cuntooyinka oo la iska indhatiro inta kale. Sababtoo ah maaddooyinka kala duwan ee firfircoon ee ku jira cuntooyinka ayaa laga yaabaa inay saameyn iska soo horjeeda ku yeeshaan darawalada kansarka - ma qaadan kartid maaddooyinka firfircoon ee cuntooyinka iyo kaabayaasha si loo gaaro go'aanka nafaqada ee Mastocytosis System.

HAA – DOORASHOOYINKA CUNTADA EE KANSARKA WAXAY U TAAGAN YAHAY. GO'AANKA NAFAQADA waa in ay tixgeliyaan dhammaan walxaha firfircoon ee CUNTADA.

Xirfadaha Looga Baahan Yahay Nafaqaynta Shakhsiyaynta ee Mastocytosis Nidaamka?

Nafaqada shakhsi ahaaneed ee kansarrada sida Systemic Mastocytosis waxay ka kooban tahay cuntooyin/kaabyo lagu taliyey; Cuntooyinka aan lagu talin/kabka tusaale ahaan cunto karinta kuwaas oo mudnaanta siiya isticmaalka cuntooyinka lagu taliyay. Tusaale nafaqeynta gaarka ah ayaa tan lagu arki karaa link.

Go'aaminta cuntooyinka lagu taliyay iyo kuwa aan lagu talin waa mid aad u adag, oo u baahan khibrad ku saabsan biology Systemic Mastocytosis, sayniska cuntada, genetics, biochemistry oo ay weheliso faham wanaagsan oo ku saabsan sida daawaynta kansarka u shaqeyso iyo baylahda la xidhiidha kuwaas oo daaweyntu ay joojin karto waxtarka.

Khibradda UGU YAR EE AQOONTA EE LOO BAAHAN YAHAY NAFAQADA SHAQSIYADEEDKA KANSARKA WAA: NOLOLIGA KANSARKA, CUNTADA CUNTADA, DAAWAYNTA KANSARKA IYO HIDDAHA HIDDAHA.

Astaamaha kansarka sida Systemic Mastocytosis

Dhammaan kansarrada sida nidaamka Mastocytosis waxaa lagu sifeyn karaa qayb gaar ah oo ah dariiqooyin kiimikaad - dariiqooyinka saxiixa ee nidaamka Mastocytosis. Dariiqooyin kiimikaad sida JAK-STAT Signaling, MAPK Signaling, PI3K-AKT-MTOR Signaling, RAS-RAF Signaling waa qayb ka mid ah qeexida saxeexa ee mastocytosis systemic. Hidde-sideyaasha kansarku qof walba wuu ka duwanaan karaa sidaas darteed saxiixooda gaarka ah ee kansarku wuxuu noqon karaa mid gaar ah.

Daawaynta waxtarka u leh mastocytosis habaysan waxay u baahan yihiin inay gartaan saxeexa dariiqooyinka biochemical ee la xidhiidha bukaan kasta oo kansar ah iyo qof kasta oo khatar ugu jira hidde-sidaha. Sidaa darteed daawayn kala duwan oo leh habab kala duwan oo ficil ah ayaa waxtar u leh bukaanada kala duwan. Si la mid ah iyo sababo la mid ah cuntooyinka iyo kaabista waxay u baahan yihiin in shaqsi kasta loo gaaryeelo. Sidaa awgeed cuntooyinka iyo kaabista qaar ayaa lagula taliyaa mastocytosis systemic marka la qaadanayo daawaynta kansarka Midostaurin, iyo cuntooyinka qaar iyo kaabista laguma talinayo.

Ilaha sida cBioPortal iyo qaar kale oo badan ayaa bixiya xogta bukaan-socodka ee aan la magacaabin ee laga helay tijaabooyinka bukaan-socodka ee dhammaan calaamadaha kansarka. Xogtan waxay ka kooban tahay tafaasiisha daraasadda tijaabada caafimaad sida cabbirka saamiga / tirada bukaannada, kooxaha da'da, jinsiga, qowmiyadda, daawaynta, goobta burooyinka iyo isbeddellada hidde-sidaha.

CNOT3, DNMT3A, FLT3, NPM1 iyo KIT waa hiddo-wadaha ugu sarreeya ee la soo sheegay ee loogu talagalay Mastocytosis System. CNOT3 ayaa lagu soo warramey 50.0 % bukaannada matala dhammaan tijaabooyinka bukaan-socodka. DNMT3A waxaa lagu soo warramey 50.0 %. Isku darka xogta bukaanka ee dadweynaha ayaa daboolaya da'aha laga bilaabo ilaa . 100.0 % xogta bukaanka waxaa loo aqoonsaday inay yihiin rag. Biology Systemic Mastocytosis oo ay weheliso hidde-sideyaasha la soo sheegay ayaa si wada jir ah u qeexaya dariiqooyinka biochemical ee saxeexa dadweynaha ee kansarkan. Haddii genetics-ka burada kansarka shakhsi ahaaneed ama hiddo-wadaha ka qaybqaata khatarta sidoo kale waa la yaqaan markaa waa in sidoo kale loo isticmaalo shakhsiyaynta nafaqada.

Dookhyada nafaqeynta waa in ay iswaafaqaan shaqsi walba saxiixiisa.

Cuntada iyo Kaabayaasha loogu talagalay Mastocytosis habaysan

Bukaanka Kansarka

Bukaanjiifka kansarka ee ku jira daawaynta ama daryeelka palliative waxay u baahan yihiin inay go'aan ka gaadhaan cuntada iyo kaabista - kaloriinta cuntada ee loo baahan yahay, maaraynta waxyeellooyin kasta oo daawaynta iyo sidoo kale hagaajinta maaraynta kansarka. Dhammaan cuntooyinka dhirta ku salaysan maaha kuwo siman oo doorashada iyo kala horraysiinta cuntooyinka kuwaas oo shakhsi ahaan loo habeeyey oo loo habeeyey daawaynta kansarka ee socota waa muhiim oo dhib badan. Waa kuwan tusaalayaal siinaya tilmaamo lagu samaynayo go'aannada nafaqada.

Dooro sprouts BRUSsel ama rogrogmi?

Khudaarta Brussel sprouts waxaa ku jira waxyaabo badan oo firfircoon ama bioactives sida Isoliquiritigenin, Taxifolin, Sulforaphane, Curcumin, Lupeol. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida PI3K-AKT-MTOR Signaling, MAPK Signaling, Oncogenic Cancer Epigenetics iyo MYC Signaling iyo kuwa kale. Brussel sprouts waxaa lagula taliyaa Mastocytosis systemic marka daawaynta kansarka socota ay tahay Midostaurin. Tani waa sababta oo ah Brussel Sprouts waxay wax ka beddeshaa dariiqyada biochemical ee si cilmiyeysan loo soo sheegay si loo dareemo saameynta Midostaurin.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee qudaarta Turnip waa Isoliquiritigenin, Quercetin, Kaempferol, Taxifolin, Ellagic Acid. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida MYC Signaling, Signaling MAPK iyo PI3K-AKT-MTOR Signaling iyo kuwa kale. Turnip laguma talinayo Mastocytosis Systemic marka daawaynta kansarka ee socota ay tahay Midostaurin sababtoo ah waxay wax ka beddeshaa dariiqyada biochemical ee ka dhigaya daawaynta kansarku mid adkaysi u leh ama aan ka jawaabin.

sprouts-Brussel-ka khudaarta ah waxa lagula talinayaa marka la rogmado si loo daawado mastocytosis systemic iyo daawaynta Midostaurin.

Dooro Miraha RABBITEYE bulukeeti ama berde?

Miraha Rabbiteye Blueberry waxaa ku jira waxyaabo badan oo firfircoon ama bioactives sida Quercetin, Linalool, Geraniol, Gallic Acid, Ferulic Acid. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida MAPK Signaling iyo PI3K-AKT-MTOR Signaling iyo kuwa kale. Rabbiteye blueberry waxaa lagula talinayaa mastocytosis systemic marka daawaynta kansarka socota ay tahay Midostaurin. Tani waa sababta oo ah Rabbiteye Blueberry waxay wax ka beddeshaa dariiqyada biochemical ee si cilmiyeysan loo soo sheegay si loo dareemo saameynta Midostaurin.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee ku jira miraha miraha waa Isoliquiritigenin, Quercetin, Kaempferol, Taxifolin, Curcumin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida MAPK Signaling iyo PI3K-AKT-MTOR Signaling iyo kuwa kale. Shayga laguma talinayo Mastocytosis Systemic marka daawaynta kansarka ee socota ay tahay Midostaurin sababtoo ah waxay wax ka beddeshaa dariiqyada biochemical ee ka dhigaya daawaynta kansarku mid adkaysi u leh ama aan ka jawaabin.

BLUUEBERRY FRUIT RABBITEYE BLUEBERRY ayaa lagula taliyaa berde loogu talagalay mastocytosis habaysan iyo daawaynta Midostaurin.

Dooro lowska walnut madow ama xabadka?

Walnut madow waxaa ku jira waxyaabo badan oo firfircoon ama bioactives sida Apigenin, Isoliquiritigenin, Myricetin, Quercetin, Kaempferol. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida RAS-RAF Signaling, PI3K-AKT-MTOR Signaling iyo MYC Signaling iyo kuwa kale. Walnut madow waxa lagula talinayaa mastocytosis systemic marka daawaynta kansarka socota ay tahay Midostaurin. Tani waa sababta oo ah Walnut Black wuxuu wax ka beddelaa dariiqyada biochemical ee si cilmiyeysan loo soo sheegay si loo dareemo saameynta Midostaurin.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee ku jira Chestnut waa Apigenin, Isoliquiritigenin, Myricetin, Kaempferol, Luteolin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida PI3K-AKT-MTOR Signaling, Oncogenic Cancer Epigenetics iyo MYC Signaling iyo kuwa kale. Chestnut laguma talinayo mastocytosis nidaamsan marka daawaynta kansarka ee socota ay tahay Midostaurin sababtoo ah waxay wax ka beddeshaa dariiqyada biochemical ee ka dhigaya daawaynta kansarku mid adkaysi u leh ama aan ka jawaabin.

Walaska madow waxa lagula talinayaa laabta dusheeda si loogu daweeyo Mastocytosis habaysan iyo daawaynta Midostaurin.

Shakhsiyaadka leh Khatarta Hidde ee Kansarka

Su'aasha ay weydiiyaan shakhsiyaadka leh khatarta hidde-sidaha ee Nidaamka Mastocytosis ama taariikhda qoyska waa "Maxaan Cunnaa si ka duwan kii hore?" iyo sida ay tahay inay doortaan cuntooyinka iyo kaabista si loo maareeyo khatarta cudurka. Maadaama khatarta kansarku aanay jirin wax la qaban karo marka la eego daawaynta - go'aamada cuntooyinka iyo kaabista ayaa noqda mid muhiim ah iyo mid ka mid ah waxyaallaha aadka u yar ee la qaban karo. Dhammaan cuntooyinka dhirta ku salaysan maaha kuwo siman oo ku salaysan hidde-sidaha la aqoonsaday iyo saxeexa dariiqa - doorashooyinka cuntada iyo kaabista waa in la shakhsiyeeyo.

Dooro CAULIFLOWER ama MADAX FAALABKA?

Cauliflower khudradda waxaa ku jira waxyaabo badan oo firfircoon ama bioactives sida Isoliquiritigenin, Curcumin, Catechol, Vitamin C, Lupeol. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida PI3K-AKT-MTOR Signaling, Signaling RAS-RAF, MAPK Signaling iyo MYC Signaling iyo kuwa kale. Cauliflower ayaa lagula taliyaa khatarta ah mastocytosis nidaamsan marka khatarta hidde ee la xiriirta ay tahay CNOT3. Tani waa sababta oo ah Cauliflower waxay kordhisaa dariiqyada biochemical ee ka soo horjeeda wadayaasha saxiixa.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee ku jira Arrowhead khudradda waa Apigenin, Myricetin, Isoliquiritigenin, Kaempferol, Luteolin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida Calaamadaynta Unugyada Jirka iyo Kansarka Oncogenic Epigenetics iyo kuwa kale. Arrowhead laguma talinayo marka khatarta ah mastocytosis nidaamka marka khatarta hidde la xidhiidha waa CNOT3 sababtoo ah waxay kordhisaa dariiqooyinka saxiixa.

Ubaxa khudaarta leh ayaa lagula talinayaa korka fallaadha ee CNOT3 Khatarta hidda-socodka ee Kansarka.

Dooro Lemon Miraha ama PUMMELO?

Liin dhanaantu waxay ka kooban tahay waxyaabo badan oo firfircoon ama bioactives sida Isoliquiritigenin, D-limonene, Luteolin, Linalool, Curcumin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimiko oo kala duwan sida Histone Methylation Suppressive, RAS-RAF Signaling, PI3K-AKT-MTOR Signaling iyo MYC Signaling iyo kuwa kale. Liin dhanaantu waxa lagula taliyaa khatarta ah mastocytosis systemic marka khatarta hidde ee la xidhiidha ay tahay CNOT3. Tani waa sababta oo ah liinku wuxuu kordhiyaa dariiqyada biochemical ee ka hor imaanaya saxiixyada darawalada.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee ku jira miro Pummelo waa Apigenin, Quercetin, Isoliquiritigenin, Curcumin, Lycopene. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida PI3K-AKT-MTOR Signaling iyo MYC Signaling iyo kuwa kale. Pummelo laguma talinayo marka khatarta ah mastocytosis nidaamsan marka khatarta hidde-sidaha ee la xidhiidha ay tahay CNOT3 sababtoo ah waxay kordhisaa dariiqooyinka saxiixa.

Liin dhanaan miraha waxaa lagula talinayaa PUMMELO oo loogu talagalay CNOT3 Khatarta Hidde ee Kansarka.

Dooro BUTTERNUT lowska ama XARUNTA YURUB?

Butternut wuxuu ka kooban yahay waxyaabo badan oo firfircoon ama bioactives sida Apigenin, Myricetin, Isoliquiritigenin, Kaempferol, Luteolin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida JAK-STAT Signaling, Signaling RAS-RAF, Signaling MAPK iyo MYC Signaling iyo kuwa kale. Butternut ayaa lagula talinayaa khatarta ah mastocytosis nidaamsan marka khatarta hidde-raaca ee la xiriirta ay tahay CNOT3. Tani waa sababta oo ah Butternut waxay kordhisaa dariiqyada biochemical ee ka soo horjeeda wadayaasha saxiixa.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee Chestnut Yurub waa Apigenin, Quercetin, Myricetin, Isoliquiritigenin, Kaempferol. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida Calaamadaynta Unugyada Jirka iyo Kansarka Oncogenic Epigenetics iyo kuwa kale. Chestnut Yurub laguma talinayo marka khatarta ah mastocytosis nidaamsan marka khatarta hidda-socodka ee la xiriirta ay tahay CNOT3 sababtoo ah waxay kordhisaa dariiqooyinka saxiixa.

BUTTERNUT waxa lagula talinayaa laabta YURUB EE CNOT3 Khatarta Hidde ee Kansarka.

In Gabagabo

Cuntooyinka iyo Kaabayaasha la doortay ayaa ah go'aamo muhiim u ah kansarrada sida Systemic Mastocytosis. Bukaannada Mastocytosis ee nidaamka iyo shakhsiyaadka leh khatarta hidde-sidaha waxay had iyo jeer qabaan su'aashan: "Waa maxay cuntooyinka iyo nafaqooyinka nafaqada ee lagu taliyey aniga iyo kuwa aan ahayn?" Waxaa jira aaminsanaan guud oo ah fikrad khaldan oo ah in dhammaan cuntooyinka dhirta ku salaysan ay faa'iido yeelan karaan ama aysan ahayn laakiin aan waxyeello lahayn. Cuntooyinka qaarkood iyo kaabisyada qaarkood waxay faragelin karaan daawaynta kansarka ama waxay kor u qaadi karaan wadayaasha dariiqyada molecular ee kansarka.

Waxaa jira noocyo kala duwan oo tilmaamayaasha kansarka sida Systemic Mastocytosis, mid kasta oo leh hidde-sidaha burooyinka kala duwan oo leh kala duwanaansho genomic dheeraad ah oo qof kasta ah. Intaa waxaa dheer daawaynta kansar kasta iyo kiimoterabi kasta waxay leeyihiin hab wax-qabad oo gaar ah. Cunto kasta sida Brussel Sprouts waxay ka kooban tahay noocyo kala duwan oo bioactives ah oo tirooyin kala duwan leh, kuwaas oo saameyn ku leh noocyo kala duwan oo kala duwan oo ah dariiqyada biochemical. Qeexida nafaqeynta shakhsi ahaaneed waa talooyinka cuntada ee gaarka ah ee tilmaamaya kansarka, daawaynta, genetics, qaab nololeedka iyo arrimo kale. Go'aannada shakhsiyaynta nafaqada ee kansarka waxay u baahan yihiin aqoonta bayoolajiga kansarka, sayniska cuntada iyo fahamka daaweynta kemotherabi ee kala duwan. Ugu dambeyntii marka ay jiraan isbeddel daaweyn ama genomics cusub ayaa la aqoonsaday - shakhsiyeynta nafaqeynta waxay u baahan tahay dib-u-qiimeyn.

Xalka shakhsiyaynta nafaqeynta ee addon ayaa ka dhigaysa go'aan qaadashada mid fudud oo meesha ka saaraysa dhammaan mala-awaalka ka jawaabaya su'aasha, "Cunto noocee ah ayaan dooran karaa ama ma dooran karaa Mastocytosis System?". Kooxda edbinta badan ee addon waxaa ka mid ah dhakhaatiirta kansarka, saynisyahano caafimaad, injineerada software iyo saynisyahano xogta.

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