Nderipi gomarara raizobatsirwa nekubatanidza Vitamin B2 mukudya kwavo?

Muchidimbu

Vitamin B2 inozivikanwa zvakanyanya nekuda kwehutano hwayo uye inowanzoshandiswa nevanorwara nekenza uye avo vari panjodzi yemagene. Asi, kuchengetedzeka uye kushanda kweVitamin B2 kune varwere vegomarara kunoenderana nezvinhu zvakawanda senge chiratidzo chegomarara, chemotherapy, kumwe kurapwa, uye genetics yebundu. Kuziva kuti zvimwe zvekudya uye zvekuwedzera, senge mazambiringa uye sipinachi, zvinogona kudyidzana zvisina kunaka nemishonga yekenza uye kukonzera kusawirirana kwakakosha.

Kudya kwakakosha pakurapwa kenza nekuti kunogona kukanganisa mhedzisiro yekurapa. Varwere vegomarara vanofanira kunyatsosarudza uye nekubatanidza chikafu chakakodzera uye chekuwedzera mukudya kwavo. Semuenzaniso, Vitamin B2 inogona kubatsira avo vane Primary Angiocentric Glioma vari pasi peLomustine, asi zvingasava zvakanaka kune varwere vanogamuchira Pembrolizumab yePrimary High-Grade Neuroepithelial Tumor. Uyezve, nepo Vitamin B2 ichigona kubatsira vanhu vane genetic risk factor "B2M", inogona kunge isingafungidzirwe kune avo vane imwe genetic njodzi "ASXL1". Kugadzirisa zvirongwa zvekudya zvinoenderana nehutano, kurapwa, uye genetics kwakakosha.

Kunzwisisa kuti kuita sarudzo pakukodzera kweVitamin B2 kune murwere wegomarara kunofanirwa kuve munhu mumwe kwakakosha. Zvinhu zvakakosha serudzi rwegomarara, nzira dzekurapa, genetic makeup, njodzi dzemajini, zera, uremu hwemuviri, uye mararamiro zvakakosha pakusarudza kana Vitamin B2 iriyo sarudzo yakakodzera. Genetics uye genomics, kunyanya, inonyanya kutariswa. Sezvo zvinhu izvi zvichigona kushanduka, zvakakosha kuti ugare uchiongorora uye kugadzirisa sarudzo dzekudya kuti dzienderane nekuchinja kwehutano uye kurapwa.

Mukupedzisa, nzira yakasarudzika yesarudzo yekudya yakakosha, tichitarisa pane zvese zvinokonzeresa zvese zvinoshanda zvinoringana muzvikafu / zvekuwedzera seVhitamini B2 pachinzvimbo chekuongorora chega chega chega chega chega kana kuregeredza zvachose. Maonero akafara aya anosimudzira nzira inonzwisisika uye yesainzi yekuronga kudya kwegomarara.

Pfupiso Pfupiso

Kushandiswa kwezvikafu zvakadyarwa nezvirimwa uye zvekuwedzera, senge mavhitamini, maruva, zvicherwa, probiotics, uye akasiyana siyana ekuwedzera, ari kuwedzera pakati pevarwere vegomarara. Izvi zvekuwedzera zvakagadzirirwa kuendesa yakakwira yakakwira yeaya anoshanda zvimisikidzo, mazhinji acho ari mukudya kwakasiyana. Iko kusungirirwa uye kusiyanisa kwezvinhu zvinoshanda zvinosiyana pakati pezvikafu zvese uye zvekuwedzera. Zvokudya zvinowanzopa huwandu hwezvinhu zvinoshanda asi pazvishoma zvakadzika, nepo ma supplements achipa huwandu hwepamusoro hwezvimwe zvinhu.

Tichifunga nezveakasiyana esainzi uye biological mabasa ega ega rinoshanda padanho remamorekuru, zvakakosha kuti uzvidavirire kune akasanganiswa mhedzisiro yezvikamu izvi kana uchifunga nezvechikafu uye chekuwedzera chekudya kana kusadya.

Mubvunzo wakaoma unomuka: Iwe unofanirwa here kuisa Vitamin B2 mukudya kwako sechinhu chekudya kana chekuwedzera? Zvinokurudzirwa here kushandisa Vitamin B2 kana uine genetic predisposition kune cancer yakabatana neB2M gene? Ko kana pachinzvimbo chako genetic njodzi ichibva kuASXL1 gene? Zvinobatsira here kuisa Vitamin B2 mukudya kwako kana ukabatwa nePrimary High-Grade Neuroepithelial Tumor, kana kuti chirwere chako chiri Primary Angiocentric Glioma? Uyezve, manwiro ako eVitamin B2 anofanira kugadziriswa sei kana uri kurapwa Lomustine kana chirongwa chako chekurapa chichibva kuLomustine kuenda kuPembrolizumab? Izvo zvakakosha kuti uzive kuti zvirevo zviri nyore senge 'Vitamin B2 ndezvakasikwa, saka zvinogara zvichibatsira' kana 'Vitamin B2 inosimudzira kusadzivirirwa kwemuviri' haina kukwana kune ruzivo rwechikafu / chekuwedzera sarudzo.

Pamusoro pezvo, zvakakosha kuti uongorore zvakare kukodzera kwekusanganisira Vitamin B2 mukudya kwako kana paine shanduko muchirongwa chako chekurapa. Muchidimbu, kana uchiita sarudzo dzekubatanidza chikafu kana ma supplements seVitamin B2 mukudya kwako kune zvakanakira, iwe unofanirwa kufunga nezvese biochemical mhedzisiro yezvese zvinongedzo, uchifunga zvinhu zvakaita serudzi rwegomarara, marapirwo chaiwo auri kuita, genetic. predispositions, uye mararamiro esarudzo.

kenza

Kenza inoramba iri dambudziko rakakura mune zvekurapa, kazhinji ichikonzera kunetseka kwakapararira. Nekudaro, kufambira mberi kwazvino kwakavandudza marapirwo ekurapa, kunyanya kuburikidza nemaitiro ekurapa emunhu, nzira dzisingapindire dzekutarisa uchishandisa ropa uye mate samples, uye kuvandudzwa kweimmunotherapy. Kuonekwa kwekutanga uye kupindira panguva yakakodzera kwave kwakakosha mukupesvedzera zvakanaka mhedzisiro yekurapa.

Kuongororwa kweGenetic kunopa vimbiso yakakosha mukuongorora njodzi yegomarara uye kukurumidza kutanga. Nekudaro, kune vanhu vazhinji vane mhuri uye genetic predispositions kugomarara, sarudzo dzekupindira kwekurapa, kunyangwe nekutarisa nguva dzose, kazhinji dzinogumira kana hapana. Kana ukangoonekwa uine imwe mhando yegomarara, sePrimary Angiocentric Glioma kana Primary High-Grade Neuroepithelial Tumor, nzira dzekurapa dzinoda kugadziridzwa zvichienderana nebundu remunhu genetics, danho rechirwere, pamwe nezvinhu zvakaita sezera uye murume. ”

Mushure mekurapa, kuenderera mberi kwekutarisa kwakakosha kuti uone chero zviratidzo zvekenza kudzoka uye kuzivisa sarudzo dzinotevera. Vazhinji varwere vegomarara uye avo vari panjodzi vanowanzo tsvaga zano rekubatanidza zvimwe zvekudya uye zvekuwedzera mukudya kwavo, izvo zvinotora basa rakakosha mukuita kwavo kwese kwekuita sarudzo maererano nehutano hwehutano.

Mubvunzo wakaoma ndewekuti ungakonzeresa njodzi dzemajini uye negomarara chairo kana uchifunga nezvesarudzo dzekudya, senge Vitamin B2. Ko genetic njodzi yegomarara kubva mukushandurwa muB2M ine zvakafanana biochemical nzira nzira sekuchinja muASXL1? Kubva pane zvinovaka muviri, njodzi inosanganisirwa nePrimary Angiocentric Glioma inofanana nePrimary High-Grade Neuroepithelial Tumor? Uyezve, kutariswa kwekudya kunoramba kwakafanana kune avo vari kuita Pembrolizumab sevaya vanogamuchira Lomustine? Aya mafungidziro akakosha pakuita sarudzo dzechikafu kune vanhu vane njodzi dzakasiyana dzemajini uye marapirwo egomarara.

Vitamin B2 - A Nutritional Supplement

Iyo yekuwedzera Vitamin B2 inosanganisira huwandu hwezvinhu zvinoshanda, zvinosanganisira Vitamin B2, yega yega iripo panguva dzakasiyana. Izvi zvinongedzo zvinopesvedzera nzira dzemamorekuru, kunyanya Oncogenic Cancer Epigenetics uye Oncogenic Histone Methylation, iyo inoronga zvakakosha zvegomarara padanho remasero, senge bundu kukura, kupararira, uye kufa kwesero. Tichifunga izvi biological pesvedzero, kusarudza akakodzera ekuwedzera seVitamin B2, ega kana musanganiswa, inova sarudzo yakakosha mumamiriro ehutano hwegomarara. Paunenge uchifunga nezvekushandisa Vitamin B2 kune cancer, zvakakosha kufunga izvi zvakasiyana zvinhu uye maitiro. Izvi zvinodaro nekuti, zvakafanana nekurapa gomarara, kushandiswa kweVitamin B2 haisi sarudzo yepasirese yakakodzera vese vane cancer asi inoda kuve munhu.

Kusarudza Vitamin B2 Zvekuwedzera

Kutarisana nemubvunzo wekuti 'Ndirini pandinofanira kudzivirira Vitamin B2 mumamiriro ezvinhu eCancer' zvinonetsa nokuti mhinduro yacho ndeyemunhu oga - zvinongoreva 'Zvinoenderana!'. Zvakafanana nemabatiro ekurapa kwegomarara kusingashande kune wese murwere, kukosha uye kuchengetedzeka kana mabhenefiti eVitamin B2 anosiyana zvichienderana nemamiriro emunhu. Zvinhu zvakadai semhando chaiyo yegomarara, genetic predispositions, marapirwo azvino, mamwe ma supplements ari kutorwa, mararamiro, BMI, uye chero allergies zvese zvine basa mukuona kuti Vitamin B2 yakakodzera here kana kuti inofanira kudziviswa, zvichisimbisa kukosha kwekufunga kwemunhu. muzvisarudzo zvakadaro.

1. Ko Vitamin B2 Supplements ichabatsira Primary High-Grade Neuroepithelial Tumor Varwere vari kurapwa Pembrolizumab?

Primary High-Giredhi Neuroepithelial Tumor inoratidzwa neakanyanya genetic mutations, anoti ASXL1, DNMT3A uye MYCN, izvo zvinotungamira kune shanduko mubiochemical nzira, kunyanya Oncogenic Cancer Epigenetics, Suppressive Histone Methylation, Focal Adhesion uye Cell Cycle. Kubudirira kwekurapwa kwegomarara, senge Pembrolizumab, zvinoenderana nemabatiro ayo ekuita pane idzi nzira. Iro zano rakakodzera rinosanganisira kuenzanisa chiito chekurapa nenzira dzinotyaira cancer, nekudaro kuve nechokwadi chemunhu uye nzira inoshanda. Mumamiriro ezvinhu akadai, kudzivirira chikafu kana kudya kunovaka muviri kunogona kupokana nemhedzisiro yekurapa kana kuderedza kurongeka uku kwakakosha. Semuyenzaniso, iyo Vitamin B2 yekuwedzera, iyo inobata iyo Oncogenic Cancer Epigenetics, inogona kunge isiri iyo sarudzo yakanaka munyaya yePrimary High-Grade Neuroepithelial Tumor kana ichiitwa Pembrolizumab. Izvi zvinodaro nekuti zvinogona kuwedzera kufambira mberi kwechirwere kana kukanganisa kushanda kwekurapa. Pakusarudza chirongwa chekudya, zvakakosha kuti utarise zvinhu zvakaita serudzi rwegomarara, marapirwo anoenderera mberi, zera, murume kana mukadzi, BMI, mararamiro, uye chero inozivikanwa genetic mutations.

2. Ko Vitamin B2 Supplements ichabatsira here Primary Angiocentric Glioma Varwere vari kurapwa Lomustine?

Primary Angiocentric Glioma inocherechedzwa neyakajeka genetic mutations, senge KMT2D, KRAS uye MEF2B, izvo zvinokonzeresa shanduko mubiochemical nzira, kunyanya Oncogenic Cancer Epigenetics, Oncogenic Histone Methylation, Amino Acid Metabolism, G-protein-yakabatana Receptor Signaling uye Kukura Factor Signaling. . Kushanda kwekurapa cancer, seLomustine, kunotemerwa nekudyidzana kwayo nenzira idzi. Chinangwa ndechekuona kuti kurapwa kunoenderana nemakwara anotyaira cancer, achigonesa nzira yemunhu yekurapa. Muchirevo chechinyorwa chino, zvikafu kana zvekuwedzera zvinowirirana nekurapa kana kuwedzera kurongeka uku kunofanirwa kutariswa. Semuenzaniso, iyo Vitamin B2 yekuwedzera isarudzo ine musoro kune avo vane Primary Angiocentric Glioma vari pasi peLomustine. Izvi zvinodaro nekuti Vitamin B2 inokanganisa nzira dzakadai seOncogenic Cancer Epigenetics, inogona kuvharisa zvinhu zvinotyaira Primary Angiocentric Glioma kana kubatsira kushanda kweLomustine.

3. Ko Vitamin B2 Supplements Yakachengeteka Kune Vane Utano Vanhu Vane ASXL1 Mutation Associated Genetic Risk?

Makambani akasiyana-siyana anopa gene mapaneru ekuongorora njodzi yemajini emhando dzakasiyana dzegomarara. Aya mapaneru anosanganisira majini akabatana nezamu, ovarian, uterine, prostate, uye gomarara remudumbu. Kuedza aya majini kunogona kusimbisa kuongororwa uye kuzivisa kurapwa uye manejimendi nzira. Kuziva musiyano unokonzera chirwere kunogona kubatsira mukuyedza uye kuongororwa kwehama dzinogona kunge dziri panjodzi. Iyo ASXL1 gene inowanzo verengerwa mune aya mapaneru ekuongorora njodzi yegomarara.

Shanduko iri muASXL1 gene inokanganisa nzira dzebiochemical kana maitiro, akadai seOncogenic Cancer Epigenetics uye Suppressive Histone Methylation, ayo anobatanidzwa zvakananga kana zvisina kunanga mukutyaira cancer padanho remamorekuru. Kana genetic panel yakaratidza shanduko muASXL1 yakabatana nenjodzi yakawedzera yeChronic Myelomonocytic Leukemia, chikonzero chesainzi chinoratidza kudzivirira kushandiswa kwekuwedzera Vitamin B2. Izvi zvinodaro nekuti kuwedzera Vitamin B2 inokanganisa nzira dzakaita seOncogenic Cancer Epigenetics, iyo inogona kutungamira kune yakaipa mhedzisiro mumamiriro eiyo ASXL1 mutation uye ane hukama nekenza mamiriro.

4. Ko Vitamin B2 Supplements Yakachengeteka Kune Vanhu Vane Utano Vane B2M Mutation Associated Genetic Risk?

B2M inoita basa rakakosha mukuongorora njodzi yegomarara. Kuchinja muB2M kunogona kukanganisa nzira dzakakosha dzebiochemical, kusanganisira Oncogenic Histone Methylation uye Antigen Presentation, iyo inokanganisa kukura kwegomarara. Kana yako genetic panel ikaratidza shanduko muB2M yakabatana neDiffuse Large B-cell Lymphoma, funga kuisa Vitamin B2 yekuwedzera muchirongwa chako chekudya. Izvi zvinowedzera zvinogona kupesvedzera nzira dzakaita seOncogenic Histone Methylation, kubatsirwa nekupa rutsigiro rwakakodzera kune vanhu vane B2M shanduko uye zvine chekuita nehutano.

Mhedziso

Zvinhu zviviri zvakakosha zvekuyeuka ndezvekuti marapirwo egomarara uye chikafu chinovaka muviri hazvina kumbofanana kune wese munhu. Zvokudya zvinovaka muviri, kusanganisira chikafu uye zvinowedzera seVitamin B2, chishandiso chinoshanda chinogona kudzorwa newe uchitarisana negomarara.

"Ndodyei?" ndiwo mubvunzo unonyanya kubvunzwa nevarwere vegomarara uye avo vari panjodzi yegomarara. Mhinduro chaiyo ndeyekuti zvinoenderana nezvinhu zvakaita serudzi rwegomarara, genetics yebundu, marapirwo azvino, allergies, mararamiro, uye BMI.

Tora kudya kwako kwegomarara kubva kuAddon nekudzvanya chinongedzo pazasi uye kupindura mibvunzo nezve rudzi rwegomarara rako, marapirwo, mararamiro, allergies, zera, uye murume kana mukadzi.

References

• PD-1 blockade inokonzeresa mhinduro nekudzivisa adaptive immune immune resistance.
• Methyl Donor Micronutrients inoshandura DNA Methylation uye Cancer Mhedzisiro.
• IDH1/2 mutation chiratidzo chekupona uye inofanotaura mhinduro kune chemotherapy yegiredhi II gliomas inorapwa pamwe chete neradiation therapy.
• Cancer therapy inoumba kusimba kwenzvimbo ye clonal hematopoiesis.
• Kuita kwakaderera kweLSD1 kunopa pro-inflammatory gene expression profile mu riboflavin-inoshaya munhu T Lymphoma Jurkat masero.
• cBioPortal yeCancer Genomics