Ndeipi cancer yaizobatsirika nekubatanidza Pterostilbene mukudya kwavo?

Muchidimbu

Pterostilbene inozivikanwa zvakanyanya nekuda kwehutano hwayo uye inowanzoshandiswa nevarwere vegomarara uye avo vari panjodzi yemajini. Asi, kuchengetedzeka uye kushanda kwePterostilbene yevarwere vegomarara kunoenderana nezvinhu zvakawanda senge chiratidzo chegomarara, chemotherapy, mamwe marapirwo, uye bundu genetics. Kuziva kuti zvimwe zvekudya uye zvekuwedzera, senge mazambiringa uye sipinashi, zvinogona kupindirana zvisina kunaka nemishonga yekenza uye kukonzera kusawirirana kwakakosha.

Kudya kwakakosha pakurapwa kenza nekuti kunogona kukanganisa mhedzisiro yekurapa. Varwere vegomarara vanofanira kunyatsosarudza uye nekubatanidza chikafu chakakodzera uye chekuwedzera mukudya kwavo. Semuyenzaniso, Pterostilbene inogona kubatsira avo vane Primary Mucinous colorectal adenocarcinoma vari pasi peCetuximab, asi zvingasava zvakanaka kune varwere vanogamuchira Radiation yePrimary Sinonasal Adenocarcinoma. Uyezve, nepo Pterostilbene ichigona kubatsira vanhu vane genetic risk factor "TERT", inogona kusapihwa kune avo vane imwe genetic njodzi. Kugadzirisa zvirongwa zvekudya zvinoenderana nehutano, kurapwa, uye genetics kwakakosha.

Kunzwisisa kuti kuita sarudzo pakukodzera kwePterostilbene kune murwere wegomarara kunofanirwa kuve munhu mumwe kwakakosha. Zvinhu zvakakosha serudzi rwegomarara, nzira dzekurapa, genetic makeup, genetic njodzi, zera, uremu hwemuviri, uye mararamiro zvakakosha pakusarudza kana Pterostilbene iriyo sarudzo yakakodzera. Genetics uye genomics, kunyanya, inonyanya kutariswa. Sezvo zvinhu izvi zvichigona kushanduka, zvakakosha kuti ugare uchiongorora uye kugadzirisa sarudzo dzekudya kuti dzienderane nekuchinja kwehutano uye kurapwa.

Mukupedzisa, maitiro akazara esarudzo dzechikafu akakosha, tichitarisa pane zvese zvinokonzeresa zvese zvinoshanda zvinoringana muzvikafu/zvinowedzera sePterostilbene pachinzvimbo chekuongorora chega chega chinoshanda chega kana kuchiregeredza zvachose. Maonero akafara aya anosimudzira nzira inonzwisisika uye yesainzi yekuronga kudya kwegomarara.

Pfupiso Pfupiso

Kushandiswa kwezvikafu zvakadyarwa nezvirimwa uye zvekuwedzera, senge mavhitamini, maruva, zvicherwa, probiotics, uye akasiyana siyana ekuwedzera, ari kuwedzera pakati pevarwere vegomarara. Izvi zvekuwedzera zvakagadzirirwa kuendesa yakakwira yakakwira yeaya anoshanda zvimisikidzo, mazhinji acho ari mukudya kwakasiyana. Iko kusungirirwa uye kusiyanisa kwezvinhu zvinoshanda zvinosiyana pakati pezvikafu zvese uye zvekuwedzera. Zvokudya zvinowanzopa huwandu hwezvinhu zvinoshanda asi pazvishoma zvakadzika, nepo ma supplements achipa huwandu hwepamusoro hwezvimwe zvinhu.

Tichifunga nezveakasiyana esainzi uye biological mabasa ega ega rinoshanda padanho remamorekuru, zvakakosha kuti uzvidavirire kune akasanganiswa mhedzisiro yezvikamu izvi kana uchifunga nezvechikafu uye chekuwedzera chekudya kana kusadya.

Mubvunzo wakaoma unomuka: Unofanira kubatanidza Pterostilbene mukudya kwako sechinhu chechikafu kana chekuwedzera? Zvinokurudzirwa kushandisa Pterostilbene kana uine genetic predisposition kune cancer yakabatana neTERT gene? Ko kana pachinzvimbo njodzi yako yemajini ichibva kune gene? Zvinobatsira here kuisa Pterostilbene mukudya kwako kana ukawanikwa uine Primary Sinonasal Adenocarcinoma, kana kana chirwere chako chiri Primary Mucinous colorectal adenocarcinoma? Uyezve, mashandisiro ako ePterostilbene anofanira kugadziriswa sei kana uri kurapwa neCetuximab kana chirongwa chako chekurapa chichibva kuCetuximab kuenda kuRadiation? Izvo zvakakosha kuti uzive kuti zvirevo zvakareruka senge 'Pterostilbene ndezvakasikwa, saka zvinogara zvichibatsira' kana 'Pterostilbene inosimudzira kusadzivirirwa' haina kukwana kune ruzivo rwechikafu / chekuwedzera sarudzo.

Pamusoro pezvo, zvakakosha kuti uongororezve ikodzera kwekusanganisira Pterostilbene mukudya kwako kana paine shanduko muchirongwa chako chekurapa. Muchidimbu, kana uchiita sarudzo nezve kubatanidza chikafu kana ma supplements sePterostilbene mukudya kwako kune mabhenefiti ayo, iwe unofanirwa kufunga nezvese biochemical mhedzisiro yezvese zvinongedzo, uchifunga zvinhu zvakaita serudzi rwegomarara, marapirwo chaiwo auri kuita, genetic predispositions. , uye sarudzo dzemararamiro.

kenza

Kenza inoramba iri dambudziko rakakura mune zvekurapa, kazhinji ichikonzera kunetseka kwakapararira. Nekudaro, kufambira mberi kwazvino kwakavandudza marapirwo ekurapa, kunyanya kuburikidza nemaitiro ekurapa emunhu, nzira dzisingapindire dzekutarisa uchishandisa ropa uye mate samples, uye kuvandudzwa kweimmunotherapy. Kuonekwa kwekutanga uye kupindira panguva yakakodzera kwave kwakakosha mukupesvedzera zvakanaka mhedzisiro yekurapa.

Kuongororwa kweGenetic kunopa vimbiso yakakosha mukuongorora njodzi yegomarara uye kukurumidza kutanga. Nekudaro, kune vanhu vazhinji vane mhuri uye genetic predispositions kugomarara, sarudzo dzekupindira kwekurapa, kunyangwe nekutarisa nguva dzose, kazhinji dzinogumira kana hapana. Kana ukangoonekwa uine imwe mhando yegomarara, yakadai sePrimary Mucinous colorectal adenocarcinoma kana Primary Sinonasal Adenocarcinoma, nzira dzekurapa dzinofanirwa kugadziridzwa zvichienderana nebundu remunhu, danho rechirwere, pamwe nezvinhu zvakaita sezera uye murume.

Mushure mekurapa, kuenderera mberi kwekutarisa kwakakosha kuti uone chero zviratidzo zvekenza kudzoka uye kuzivisa sarudzo dzinotevera. Vazhinji varwere vegomarara uye avo vari panjodzi vanowanzo tsvaga zano rekubatanidza zvimwe zvekudya uye zvekuwedzera mukudya kwavo, izvo zvinotora basa rakakosha mukuita kwavo kwese kwekuita sarudzo maererano nehutano hwehutano.

Mubvunzo wakaoma ndewekuti ungaite here mungozi dzemajini uye negomarara rekuongororwa kana uchifunga nezvechikafu sarudzo, senge Pterostilbene. Ko genetic njodzi yegomarara kubva mukushanduka muTERT ine zvakafanana biochemical nzira nzira sekuchinja mune imwe gene? Kubva pane zvinovaka muviri, njodzi inosanganisirwa nePrimary Mucinous colorectal adenocarcinoma inoenzana nePrimary Sinonasal Adenocarcinoma? Uyezve, kutariswa kwechikafu kunoramba kwakafanana here kune avo vari kuita Radiation sevaya vanogamuchira Cetuximab? Aya mafungidziro akakosha pakuita sarudzo dzechikafu kune vanhu vane njodzi dzakasiyana dzemajini uye marapirwo egomarara.

Pterostilbene - A Nutritional Supplement

Iyo yekuwedzera Pterostilbene inombundira huwandu hwezvinhu zvinoshanda, zvinosanganisira Pterostilbene, yega yega iripo panguva dzakasiyana. Izvi zvinongedzo zvinopesvedzera nzira dzemamorekuru, kunyanya MYC Signaling, Notch Signaling, Chromatin Remodeling uye Cell Cycle, iyo inodzora zvinhu zvakakosha zvegomarara padanho remasero, sekukura kwebundu, kupararira, uye kufa kwesero. Tichifunga izvi biological pesvedzero, kusarudza akakodzera anowedzera sePterostilbene, ari ega kana musanganiswa, inova sarudzo yakakosha mumamiriro ehutano hwegomarara. Kana uchifunga kushandisa Pterostilbene yegomarara, zvakakosha kuti utarise izvi zvakasiyana zvinhu uye maitiro. Izvi zvinodaro nekuti, zvakafanana nekurapa cancer, kushandiswa kwePterostilbene haisi sarudzo yepasirese yakakodzera vese cancer asi inoda kuve munhu.

Kusarudza Pterostilbene Supplements

Kugadzirisa mubvunzo wekuti 'Ndirini pandinofanira kudzivirira Pterostilbene mumamiriro ezvinhu eCancer' zvinonetsa nekuti mhinduro yacho ndeyemunhu mumwe chete - inongo 'Inoenderana!'. Zvakafanana nemabatiro api neapi ekurapa cancer anogona kusashanda kune wese murwere, kukosha uye kuchengetedzeka kana mabhenefiti ePterostilbene anosiyana zvichienderana nemamiriro emunhu. Zvinhu zvakadai semhando chaiyo yegomarara, genetic predispositions, marapirwo azvino, zvimwe zvekuwedzera zviri kutorwa, mararamiro, BMI, uye chero allergies zvese zvinotora chikamu mukuona kuti Pterostilbene yakakodzera here kana kuti inofanirwa kudziviswa, zvichisimbisa kukosha kwekufunga kwemunhu. zvisarudzo zvakadaro.

1. Ko Pterostilbene Supplements ichabatsira Varwere vePrimary Sinonasal Adenocarcinoma vari kurapwa neRadiation?

Yekutanga Sinonasal Adenocarcinoma inoratidzwa neakanyanya genetic mutations, anoti ATRX, NOTCH1 uye PTPRD, izvo zvinotungamira kune shanduko mubiochemical nzira, kunyanya Notch Signaling uye RUNX Signaling. Kubudirira kwekurapwa kwegomarara, senge Radiation, zvinoenderana nemaitiro ayo ekuita pane idzi nzira dzakananga. Iro zano rakakodzera rinosanganisira kuenzanisa chiito chekurapa nenzira dzinotyaira cancer, nekudaro kuve nechokwadi chemunhu uye nzira inoshanda. Mumamiriro ezvinhu akadai, kudzivirira chikafu kana kudya kunovaka muviri kunogona kupokana nemhedzisiro yekurapa kana kuderedza kurongeka uku kwakakosha. Semuyenzaniso, iyo Pterostilbene yekuwedzera, iyo inobata iyo Notch Signaling, inogona kunge isiri iyo sarudzo chaiyo munyaya yePrimary Sinonasal Adenocarcinoma kana ichiitwa neRadiation. Izvi zvinodaro nekuti zvinogona kuwedzera kufambira mberi kwechirwere kana kukanganisa kushanda kwekurapa. Pakusarudza chirongwa chekudya, zvakakosha kuti utarise zvinhu zvakaita serudzi rwegomarara, marapirwo anoenderera mberi, zera, murume kana mukadzi, BMI, mararamiro, uye chero inozivikanwa genetic mutations.

2. Ko Pterostilbene Supplements ichabatsira here Primary Mucinous colorectal adenocarcinoma Varwere vari kurapwa Cetuximab?

Primary Mucinous colorectal adenocarcinoma inotaridzwa nechaiyo genetic mutations, seTTN, APC uye KRAS, izvo zvinokonzeresa shanduko mubiochemical nzira, kunyanya MYC Signaling, Angiogenesis, G-protein-coupled Receptor Signaling uye Growth Factor Signaling. Kushanda kwekurapa cancer, senge Cetuximab, kunotemerwa nekudyidzana kwayo nenzira idzi. Chinangwa ndechekuona kuti kurapwa kunoenderana nemakwara anotyaira cancer, achigonesa nzira yekurapa yemunhu. Muchirevo chechinyorwa chino, zvekudya kana zvekuwedzera zvinowirirana nekurapa kana kuwedzera kurongeka uku kunofanirwa kutariswa. Semuenzaniso, iyo Pterostilbene yekuwedzera isarudzo ine musoro kune avo vane Primary Mucinous colorectal adenocarcinoma iri pasi peCetuximab. Izvi zvinodaro nekuti Pterostilbene inofurira nzira dzakadai seMYC Signaling, inogona kuvharisa zvinhu zvinotyaira Primary Mucinous colorectal adenocarcinoma kana kubatsira kushanda kweCetuximab.

3. Pterostilbene Supplements Yakachengeteka Kune Vanhu Vane Utano Vane TERT Mutation Yakabatana Nengozi YeGenetic?

TERT inoita basa rakakosha mukuongorora njodzi yegomarara. Shanduko muTERT inogona kukanganisa nzira dzakakosha dzebiochemical, kusanganisira Cell Cycle uye DNA Repair, izvo zvinokanganisa kukura kwegomarara. Kana yako genetic panel ikaratidza shanduko muTERT yakabatana neHematological Cancer, funga kubatanidza Pterostilbene yekuwedzera muchirongwa chako chekudya. Izvi zvinowedzera zvinogona kupesvedzera nzira dzakaita seCell Cycle, kubatsirwa nekupa rutsigiro rwakakodzera kune vanhu vane TERT shanduko uye zvine chekuita nehutano.

Mhedziso

Zvinhu zviviri zvakakosha zvekuyeuka ndezvekuti marapirwo egomarara uye chikafu chinovaka muviri hazvina kumbofanana kune wese munhu. Zvokudya zvinovaka muviri, kusanganisira chikafu uye zvekuwedzera sePterostilbene, chishandiso chinoshanda chinogona kudzorwa newe uchitarisana negomarara.

"Ndodyei?" ndiwo mubvunzo unonyanya kubvunzwa nevarwere vegomarara uye avo vari panjodzi yegomarara. Mhinduro chaiyo ndeyekuti zvinoenderana nezvinhu zvakaita serudzi rwegomarara, genetics yebundu, marapirwo azvino, allergies, mararamiro, uye BMI.

Tora kudya kwako kwegomarara kubva kuAddon nekudzvanya chinongedzo pazasi uye kupindura mibvunzo nezve rudzi rwegomarara rako, marapirwo, mararamiro, allergies, zera, uye murume kana mukadzi.

References

• Kuenzanisa kwemapoka kana mhedzisiro iri pachiyero chakarairwa.
• cBioPortal yeCancer Genomics
• Targeting Notch kukunda radiation kuramba.
• Kudya kwekudya kwepterostilbene, chikamu cheblueberries, inhibits iyo beta-catenin / p65 yakadzika nzira yekusaina nzira uye colon carcinogenesis mumakonzo.
• Pterostilbene inoshandisa antitumor chiitiko kuburikidza neNotch1 yekusaina nzira mumapapu emunhu adenocarcinoma masero.
• Pterostilbene pasi-inogadzirisa hTERT pakudzika kwemuviri mumasero egomarara rezamu: Zvinogoneka kuburikidza nekudzivirirwa kwecMyc.
• Pan-cancer kuongororwa kweiyo genomes yakazara.
• cBioPortal yeCancer Genomics
• Mutational landscape yekenza yemetastatic yakaratidzwa kubva kune vangangove vanotarisirwa kutevedzana kwevarwere zviuru gumi.