Nderipi gomarara raizobatsirwa nekubatanidza Perilla mukudya kwavo?

Muchidimbu

Perilla inozivikanwa zvakanyanya nekuda kwehutano hwayo uye inowanzoshandiswa nevarwere vegomarara uye avo vari panjodzi yemajini. Asi, kuchengetedzeka uye kushanda kwePerilla yevarwere vegomarara kunoenderana nezvinhu zvakawanda senge chiratidzo chegomarara, chemotherapy, kumwe marapirwo, uye genetics yebundu. Kuziva kuti zvimwe zvekudya uye zvekuwedzera, senge mazambiringa uye sipinachi, zvinogona kudyidzana zvisina kunaka nemishonga yekenza uye kukonzera kusawirirana kwakakosha.

Kudya kwakakosha pakurapwa kenza nekuti kunogona kukanganisa mhedzisiro yekurapa. Varwere vegomarara vanofanira kunyatsosarudza uye nekubatanidza chikafu chakakodzera uye chekuwedzera mukudya kwavo. Semuenzaniso, Perilla inogona kubatsira avo vane Primary Small Cell Bladder Cancer vari pasi peMethotrexate, asi zvingasava zvakanaka kune varwere vanowana Radiation yePrimary Urethral Squamous Cell Carcinoma. Uyezve, nepo Perilla achigona kubatsira vanhu vane genetic risk factor "KMT2D", inogona kunge isinga taurirwe kune avo vane imwe genetic ngozi "B2M". Kugadzirisa zvirongwa zvekudya zvinoenderana nehutano, kurapwa, uye genetics kwakakosha.

Kunzwisisa kuti kuita sarudzo pakukodzera kwePerilla kune murwere wegomarara kunofanirwa kuve munhu mumwe kwakakosha. Zvinhu zvakakosha serudzi rwegomarara, nzira dzekurapa, genetic makeup, genetic njodzi, zera, uremu hwemuviri, uye mararamiro zvakakosha pakusarudza kana Perilla iriyo sarudzo yakakodzera. Genetics uye genomics, kunyanya, inonyanya kutariswa. Sezvo zvinhu izvi zvichigona kushanduka, zvakakosha kuti ugare uchiongorora uye kugadzirisa sarudzo dzekudya kuti dzienderane nekuchinja kwehutano uye kurapwa.

Mukupedzisa, maitiro akazara esarudzo dzekudya akakosha, achitarisa pane zvese zvinokonzeresa zvese zvinoshanda zvinoringana muzvikafu / zvekuwedzera sePerilla pachinzvimbo chekuongorora chega chega chinoshanda chega kana kuregeredza zvachose. Maonero akafara aya anosimudzira nzira inonzwisisika uye yesainzi yekuronga kudya kwegomarara.

Pfupiso Pfupiso

Kushandiswa kwezvikafu zvakadyarwa nezvirimwa uye zvekuwedzera, senge mavhitamini, maruva, zvicherwa, probiotics, uye akasiyana siyana ekuwedzera, ari kuwedzera pakati pevarwere vegomarara. Izvi zvekuwedzera zvakagadzirirwa kuendesa yakakwira yakakwira yeaya anoshanda zvimisikidzo, mazhinji acho ari mukudya kwakasiyana. Iko kusungirirwa uye kusiyanisa kwezvinhu zvinoshanda zvinosiyana pakati pezvikafu zvese uye zvekuwedzera. Zvokudya zvinowanzopa huwandu hwezvinhu zvinoshanda asi pazvishoma zvakadzika, nepo ma supplements achipa huwandu hwepamusoro hwezvimwe zvinhu.

Tichifunga nezveakasiyana esainzi uye biological mabasa ega ega rinoshanda padanho remamorekuru, zvakakosha kuti uzvidavirire kune akasanganiswa mhedzisiro yezvikamu izvi kana uchifunga nezvechikafu uye chekuwedzera chekudya kana kusadya.

Mubvunzo wakaoma unomuka: Iwe unofanirwa here kubatanidza Perilla mukudya kwako sechinhu chekudya kana chekuwedzera? Zvinogoneka here kushandisa Perilla kana iwe uine genetic predisposition kune cancer yakabatana neKMT2D gene? Ko kana pachinzvimbo chako genetic njodzi ichibva kuB2M gene? Zvinobatsira here kuisa Perilla mukudya kwako kana wabatwa nePrimary Urethral Squamous Cell Carcinoma, kana kuti chirwere chako chiri Primary Small Cell Bladder Cancer? Uyezve, manwiro ako ePerilla anofanira kugadziriswa sei kana uri kurapwa neMethotrexate kana chirongwa chako chekurapa chichibva kuMethotrexate kuenda kuRadiation? Izvo zvakakosha kuti uzive kuti zvirevo zviri nyore senge 'Perilla ndezvakasikwa, saka zvinogara zvichibatsira' kana kuti 'Perilla inosimudzira kusadzivirirwa' hazvina kukwana kune ruzivo rwekudya / yekuwedzera sarudzo.

Pamusoro pezvo, zvakakosha kuti uongorore zvakare kukodzera kwekubatanidza Perilla mukudya kwako kana paine shanduko muchirongwa chako chekurapa. Muchidimbu, kana uchiita sarudzo nezve kubatanidza chikafu kana ma supplements sePerilla mukudya kwako kune mabhenefiti ayo, iwe unofanirwa kufunga nezvese biochemical mhedzisiro yezvese zvinongedzo, uchifunga zvinhu zvakaita serudzi rwegomarara, marapirwo chaiwo auri kuita, genetic predispositions. , uye sarudzo dzemararamiro.

kenza

Kenza inoramba iri dambudziko rakakura mune zvekurapa, kazhinji ichikonzera kunetseka kwakapararira. Nekudaro, kufambira mberi kwazvino kwakavandudza marapirwo ekurapa, kunyanya kuburikidza nemaitiro ekurapa emunhu, nzira dzisingapindire dzekutarisa uchishandisa ropa uye mate samples, uye kuvandudzwa kweimmunotherapy. Kuonekwa kwekutanga uye kupindira panguva yakakodzera kwave kwakakosha mukupesvedzera zvakanaka mhedzisiro yekurapa.

Kuongororwa kweGenetic kunopa vimbiso yakakosha mukuongorora njodzi yegomarara uye kukurumidza kutanga. Nekudaro, kune vanhu vazhinji vane mhuri uye genetic predispositions kugomarara, sarudzo dzekupindira kwekurapa, kunyangwe nekutarisa nguva dzose, kazhinji dzinogumira kana hapana. Kana waonekwa kuti une imwe mhando yegomarara, sePrimary Diki Cell Bladder Cancer kana Primary Urethral Squamous Cell Carcinoma, nzira dzekurapa dzinofanirwa kugadziridzwa zvichienderana nebundu remunhu genetics, danho rechirwere, pamwe nezvinhu zvakaita sezera uye murume. .”

Mushure mekurapa, kuenderera mberi kwekutarisa kwakakosha kuti uone chero zviratidzo zvekenza kudzoka uye kuzivisa sarudzo dzinotevera. Vazhinji varwere vegomarara uye avo vari panjodzi vanowanzo tsvaga zano rekubatanidza zvimwe zvekudya uye zvekuwedzera mukudya kwavo, izvo zvinotora basa rakakosha mukuita kwavo kwese kwekuita sarudzo maererano nehutano hwehutano.

Mubvunzo wakaoma ndewekuti ungakonzeresa njodzi dzemajini uye negomarara chairo kana uchifunga nezvesarudzo dzekudya, senge Perilla. Ko genetic njodzi yegomarara kubva mukushanduka muKMT2D ine zvakafanana biochemical nzira nzira sekuchinja muB2M? Kubva pamaonero ezvekudya kunovaka muviri, njodzi inosanganisirwa nePrimary Small Cell Bladder Cancer inofanana nePrimary Urethral Squamous Cell Carcinoma? Uyezve, kutariswa kwekudya kunoramba kwakafanana kune avo vari kuita Radiation sevaya vanogamuchira Methotrexate? Aya mafungidziro akakosha pakuita sarudzo dzechikafu kune vanhu vane njodzi dzakasiyana dzemajini uye marapirwo egomarara.

Perilla – A Nutritional Supplement

Iyo yekuwedzera Perilla inosanganisira huwandu hwezvinhu zvinoshanda, zvinosanganisira Stigmasterol, Shikimic Acid, Perillaldehyde, Linalool uye Caffeic Acid, imwe neimwe iripo panguva dzakasiyana. Izvi zvinongedzo zvinopesvedzera nzira dzemamorekuru, kunyanya MYC Signaling, DNA Repair, TWEAK Signaling uye DAP12 Signaling, iyo inoronga zvakakomba zvegomarara padanho remasero, sekukura kwebundu, kupararira, uye kufa kwesero. Tichifunga izvi biological pesvedzero, kusarudza iwo akakodzera ekuwedzera sePerilla, ari ega kana musanganiswa, inova sarudzo yakakosha mumamiriro ehutano hwegomarara. Paunenge uchifunga kushandisa Perilla yegomarara, zvakakosha kuti utarise izvi zvakasiyana zvinhu uye maitiro. Izvi zvinodaro nekuti, zvakafanana nekurapa cancer, kushandiswa kwePerilla haisi sarudzo yepasirese yakakodzera vese cancer asi inoda kuve munhu.

Kusarudza Perilla Supplements

Kugadzirisa mubvunzo wekuti 'Ndirini pandinofanira kudzivirira Perilla mumamiriro eCancer' zvinonetsa nekuti mhinduro yacho ndeyemunhu mumwe chete - zvinongoreva 'Zvinoenderana!'. Zvakafanana nemabatiro ekurapa kwegomarara anogona kusashanda kune wese murwere, kukosha uye kuchengetedzeka kana mabhenefiti ePerilla anosiyana zvichienderana nemamiriro emunhu. Zvinhu zvakadai semhando chaiyo yegomarara, genetic predispositions, marapirwo azvino, mamwe ma supplements ari kutorwa, mararamiro, BMI, uye chero allergies zvese zvine basa mukuona kuti Perilla yakakodzera here kana kuti inofanirwa kudziviswa, zvichisimbisa kukosha kwekufunga kwemunhu. zvisarudzo zvakadaro.

1. Ko Perilla Supplements ichabatsira here Primary Urethral Squamous Cell Carcinoma Varwere vari kurapwa neRadiation?

Yekutanga Urethral Squamous Cell Carcinoma inoratidzwa nekumwe genetic mutations, iyo BLM, BRCA1 uye CTCF, izvo zvinotungamira kune shanduko mubiochemical nzira, kunyanya Androgen Signaling uye DNA Repair. Kubudirira kwekurapwa kwegomarara, senge Radiation, zvinoenderana nemaitiro ayo ekuita pane idzi nzira dzakananga. Iro zano rakakodzera rinosanganisira kuenzanisa chiito chekurapa nenzira dzinotyaira cancer, nekudaro kuve nechokwadi chemunhu uye nzira inoshanda. Mumamiriro ezvinhu akadai, kudzivirira chikafu kana kudya kunovaka muviri kunogona kupokana nemhedzisiro yekurapa kana kuderedza kurongeka uku kwakakosha. Semuyenzaniso, iyo Perilla yekuwedzera, iyo inobata iyo DNA Kugadziriswa, inogona kunge isiri iyo sarudzo yakanaka munyaya yePrimary Urethral Squamous Cell Carcinoma kana ichiitwa neRadiation. Izvi zvinodaro nekuti zvinogona kuwedzera kufambira mberi kwechirwere kana kukanganisa kushanda kwekurapa. Pakusarudza chirongwa chekudya, zvakakosha kuti utarise zvinhu zvakaita serudzi rwegomarara, marapirwo anoenderera mberi, zera, murume kana mukadzi, BMI, mararamiro, uye chero inozivikanwa genetic mutations.

2. Ko Perilla Supplements ichabatsira Varwere veGomarara Dundi reDundira Varwere vari kurapwa neMethotrexate?

Chekutanga Diki Cell Dundi Regomarara rinoonekwa neakananga genetic mutations, seTERT neTP53, izvo zvinokonzeresa shanduko mubiochemical nzira, kunyanya MYC Signaling, Cell Cycle Checkpoints uye Apoptosis. Kushanda kwekurapa kenza, seMethotrexate, kunotemerwa nekudyidzana kwayo nenzira idzi. Chinangwa ndechekuona kuti kurapwa kunoenderana nemakwara anotyaira cancer, achigonesa nzira yekurapa yemunhu. Muchirevo chechinyorwa chino, zvekudya kana zvekuwedzera zvinowirirana nekurapa kana kuwedzera kurongeka uku kunofanirwa kutariswa. Semuenzaniso, iyo Perilla yekuwedzera isarudzo ine musoro kune avo vane Primary Diki Cell Bladder Cancer iri pasi peMethotrexate. Izvi zvinodaro nekuti Perilla inokanganisa nzira dzakaita seMYC Signaling, inogona kuvharisa zvinhu zvinotyaira Primary Diki Cell Bladder Cancer kana kubatsira kushanda kweMethotrexate.

3. Ko Perilla Supplements Yakachengeteka Kune Vanhu Vane Utano Vane B2M Mutation Yakabatana Nengozi YeGenetic?

Makambani akasiyana-siyana anopa gene mapaneru ekuongorora njodzi yemajini emhando dzakasiyana dzegomarara. Aya mapaneru anosanganisira majini akabatana nezamu, ovarian, uterine, prostate, uye gomarara remudumbu. Kuedza aya majini kunogona kusimbisa kuongororwa uye kuzivisa kurapwa uye manejimendi nzira. Kuziva musiyano unokonzera chirwere kunogona kubatsira mukuyedza uye kuongororwa kwehama dzinogona kunge dziri panjodzi. Iyo B2M gene inowanzo verengerwa mune aya mapaneru ekuongorora njodzi yegomarara.

Shanduko iri muB2M gene inokanganisa nzira dzebiochemical kana maitirwo, akadai se TWEAK Signaling uye Antigen Presentation, ayo anobatanidzwa zvakananga kana zvisina kunanga mukutyaira cancer padanho remamorekuru. Kana genetic panel yakaratidza shanduko muB2M yakabatana nenjodzi yakawedzera yeDiffuse Large B-cell Lymphoma, zvikonzero zvesainzi zvinoratidza kudzivirira kushandiswa kwekuwedzera Perilla. Izvi zvinodaro nekuti yekuwedzera Perilla inopesvedzera nzira senge TWEAK Signaling, iyo inogona kutungamira kune yakaipa mhedzisiro mumamiriro eiyo B2M shanduko uye ane hukama nekenza mamiriro.

4. Ko Perilla Supplements Yakachengeteka Kune Vanhu Vane Utano Vane KMT2D Mutation Associated Genetic Risk?

KMT2D inoita basa rakakosha mukuongorora njodzi yegomarara. Kuchinja muKMT2D kunogona kukanganisa nzira dzakakosha dzebiochemical, kusanganisira DAP12 Signaling uye Oncogenic Histone Methylation, iyo inokanganisa kukura kwegomarara. Kana genetic panel yako ikaratidza shanduko muKMT2D yakabatana neBladder Urothelial Carcinoma, funga kuisa Perilla supplement muchirongwa chako chekudya. Izvi zvinowedzera zvinogona kupesvedzera nzira dzakaita seDAP12 Signaling, kubatsirwa nekupa rutsigiro rwakakodzera kune vanhu vane KMT2D shanduko uye zvine chekuita nehutano.

Mhedziso

Zvinhu zviviri zvakakosha zvekuyeuka ndezvekuti marapirwo egomarara uye chikafu chinovaka muviri hazvina kumbofanana kune wese munhu. Zvokudya zvinovaka muviri, kusanganisira chikafu uye zvekuwedzera sePerilla, chishandiso chinoshanda chinogona kudzorwa newe uchitarisana negomarara.

"Ndodyei?" ndiwo mubvunzo unonyanya kubvunzwa nevarwere vegomarara uye avo vari panjodzi yegomarara. Mhinduro chaiyo ndeyekuti zvinoenderana nezvinhu zvakaita serudzi rwegomarara, genetics yebundu, marapirwo azvino, allergies, mararamiro, uye BMI.

Tora kudya kwako kwegomarara kubva kuAddon nekudzvanya chinongedzo pazasi uye kupindura mibvunzo nezve rudzi rwegomarara rako, marapirwo, mararamiro, allergies, zera, uye murume kana mukadzi.

References

• Caffeic acid, phenolic phytochemical mukofi, inodzivisa zvakananga basa reFyn kinase uye UVB-induced COX-2 kutaura.
• Chromatographic kupatsanurwa uye electrochemical kutsunga kwecholesterol hydroperoxides inogadzirwa nephotodynamic chiito.
• cBioPortal yeCancer Genomics
• Integrative kliniki genomics yekenza yemetastatic.
• Kudzikira kwemhinduro dzekuzvimba neinoveli caffeic acid ester derivative nekudzivisa NF-kappa B.
• Histone deacetylase inhibitor inodzoreredza kuramba kwemishonga yakawanda nekudzikamisa iyo nucleophosmin nhanho kuburikidza nePI3K/Akt nzira mugomarara rezamu.
• Mutational landscape yekenza yemetastatic yakaratidzwa kubva kune vangangove vanotarisirwa kutevedzana kwevarwere zviuru gumi.