Nderipi gomarara raizobatsirwa nekubatanidza Pedra mukudya kwavo?

Muchidimbu

Pedra inozivikanwa zvakanyanya nekuda kwehutano hwayo uye inowanzoshandiswa nevanorwara nekenza uye avo vari panjodzi yemajini. Asi, kuchengetedzeka uye kushanda kwePedra kune varwere vegomarara kunoenderana nezvinhu zvakawanda senge chiratidzo chegomarara, chemotherapy, kumwe kurapwa, uye genetics yebundu. Kuziva kuti zvimwe zvekudya uye zvekuwedzera, senge mazambiringa uye sipinachi, zvinogona kudyidzana zvisina kunaka nemishonga yekenza uye kukonzera kusawirirana kwakakosha.

Kudya kwakakosha pakurapwa kenza nekuti kunogona kukanganisa mhedzisiro yekurapa. Varwere vegomarara vanofanira kunyatsosarudza uye nekubatanidza chikafu chakakodzera uye chekuwedzera mukudya kwavo. Semuyenzaniso, Pedra inogona kubatsira avo vane Primary Stomach Adenocarcinoma vari pasi peOxaliplatin, asi zvingasava zvakanaka kune varwere vanogamuchira Trifluridine yePrimary Stomach signet ring cell carcinoma. Uyezve, nepo Pedra achigona kubatsira vanhu vane genetic risk factor "ALK", inogona kusapihwa kune avo vane imwe genetic ngozi "KMT2D". Kugadzirisa zvirongwa zvekudya zvinoenderana nehutano, kurapwa, uye genetics kwakakosha.

Kunzwisisa kuti kuita sarudzo pakukodzera kwePedra kune murwere wegomarara kunofanirwa kuve munhu mumwe kwakakosha. Zvinhu zvakakosha serudzi rwegomarara, nzira dzekurapa, genetic makeup, njodzi dzemajini, zera, uremu hwemuviri, uye mararamiro zvakakosha pakusarudza kana Pedra iriyo sarudzo yakakodzera. Genetics uye genomics, kunyanya, inonyanya kutariswa. Sezvo zvinhu izvi zvichigona kushanduka, zvakakosha kuti ugare uchiongorora uye kugadzirisa sarudzo dzekudya kuti dzienderane nekuchinja kwehutano uye kurapwa.

Mukupedzisa, maitiro akazara esarudzo dzekudya akakosha, achitarisa pane zvese zvinokonzeresa zvese zvinoshanda zvinoriumba muzvokudya/zvinowedzera sePedra pane kuongorora chimwe nechimwe chinoshandiswa chinoshandiswa zvakasiyana kana kusachifuratira zvachose. Maonero akafara aya anosimudzira nzira inonzwisisika uye yesainzi yekuronga kudya kwegomarara.

Pfupiso Pfupiso

Kushandiswa kwezvikafu zvakadyarwa nezvirimwa uye zvekuwedzera, senge mavhitamini, maruva, zvicherwa, probiotics, uye akasiyana siyana ekuwedzera, ari kuwedzera pakati pevarwere vegomarara. Izvi zvekuwedzera zvakagadzirirwa kuendesa yakakwira yakakwira yeaya anoshanda zvimisikidzo, mazhinji acho ari mukudya kwakasiyana. Iko kusungirirwa uye kusiyanisa kwezvinhu zvinoshanda zvinosiyana pakati pezvikafu zvese uye zvekuwedzera. Zvokudya zvinowanzopa huwandu hwezvinhu zvinoshanda asi pazvishoma zvakadzika, nepo ma supplements achipa huwandu hwepamusoro hwezvimwe zvinhu.

Tichifunga nezveakasiyana esainzi uye biological mabasa ega ega rinoshanda padanho remamorekuru, zvakakosha kuti uzvidavirire kune akasanganiswa mhedzisiro yezvikamu izvi kana uchifunga nezvechikafu uye chekuwedzera chekudya kana kusadya.

Mubvunzo wakaoma unomuka: Unofanira kubatanidza Pedra mukudya kwako sechinhu chekudya kana chekuwedzera? Zvinokurudzirwa here kushandisa Pedra kana uine genetic predisposition kune cancer yakabatana neiyo ALK gene? Ko kana pachinzvimbo chako genetic njodzi ichibva kuKMT2D gene? Zvinobatsira here kuisa Pedra mukudya kwako kana wabatwa nePrimary Stomach signet ring cell carcinoma, kana kuti chirwere chako chiri Primary Stomach Adenocarcinoma? Uyezve, manwiro ako ePedra anofanira kugadziriswa sei kana uri kurapwa neOxaliplatin kana chirongwa chako chekurapa chichibva kuOxaliplatin kuenda kuTrifluridine? Izvo zvakakosha kuti uzive kuti zvirevo zviri nyore senge 'Pedra ndeyemusikirwo, saka zvinogara zvichibatsira' kana 'Pedra inosimudzira kusadzivirirwa' haina kukwana kune ruzivo rwekudya / yekuwedzera sarudzo.

Uyezve, zvakakosha kuti uongorore zvakare kukodzera kwekubatanidza Pedra mukudya kwako kana pane shanduko mukurapa kwako. Muchidimbu, paunenge uchiita sarudzo nezve kubatanidza chikafu kana ma supplements sePedra mukudya kwako kune zvakanakira, iwe unofanirwa kufunga nezvesese biochemical mhedzisiro yezvinhu zvese zvinongedzo, uchifunga nezvemhando dzakadai serudzi rwegomarara, marapirwo chaiwo auri kuita, genetic predispositions. , uye sarudzo dzemararamiro.

kenza

Kenza inoramba iri dambudziko rakakura mune zvekurapa, kazhinji ichikonzera kunetseka kwakapararira. Nekudaro, kufambira mberi kwazvino kwakavandudza marapirwo ekurapa, kunyanya kuburikidza nemaitiro ekurapa emunhu, nzira dzisingapindire dzekutarisa uchishandisa ropa uye mate samples, uye kuvandudzwa kweimmunotherapy. Kuonekwa kwekutanga uye kupindira panguva yakakodzera kwave kwakakosha mukupesvedzera zvakanaka mhedzisiro yekurapa.

Kuongororwa kweGenetic kunopa vimbiso yakakosha mukuongorora njodzi yegomarara uye kukurumidza kutanga. Nekudaro, kune vanhu vazhinji vane mhuri uye genetic predispositions kugomarara, sarudzo dzekupindira kwekurapa, kunyangwe nekutarisa nguva dzose, kazhinji dzinogumira kana hapana. Kana waonekwa kuti une imwe mhando yegomarara, sePrimary Stomach Adenocarcinoma kana Primary Stomach signet ring cell carcinoma, nzira dzekurapa dzinoda kugadziridzwa zvichienderana nebundu remunhu, danho rechirwere, pamwe nezvinhu zvakaita sezera uye murume kana mukadzi. ”

Mushure mekurapa, kuenderera mberi kwekutarisa kwakakosha kuti uone chero zviratidzo zvekenza kudzoka uye kuzivisa sarudzo dzinotevera. Vazhinji varwere vegomarara uye avo vari panjodzi vanowanzo tsvaga zano rekubatanidza zvimwe zvekudya uye zvekuwedzera mukudya kwavo, izvo zvinotora basa rakakosha mukuita kwavo kwese kwekuita sarudzo maererano nehutano hwehutano.

Mubvunzo wakaoma ndewekuti ungakonzeresa njodzi dzemajini uye negomarara chairo kana uchifunga nezvesarudzo dzekudya, senge Pedra. Ko genetic njodzi yegomarara kubva mukushanduka muALK ine zvakafanana biochemical nzira nzira sekuchinja muKMT2D? Kubva pakuona kwekudya, njodzi ine chekuita nePrimary Stomach Adenocarcinoma inofananidzwa nePrimary Stomach signet ring cell carcinoma? Uyezve, kutariswa kwechikafu kunoramba kwakafanana here kune avo vari kuita Trifluridine kune avo vanogamuchira Oxaliplatin? Aya mafungidziro akakosha pakuita sarudzo dzechikafu kune vanhu vane njodzi dzakasiyana dzemajini uye marapirwo egomarara.

Pedra – A Nutritional Supplement

Iyo yekuwedzera Pedra inosanganisira huwandu hwezvinhu zvinoshanda, kusanganisira Myrcene, imwe neimwe iripo panguva dzakasiyana. Izvi zvinongedzo zvinopesvedzera nzira dzemamorekuru, kunyanya Extracellular Matrix Remodelling, TGFB Signaling uye MAPK Signaling, iyo inoronga zvakakosha zvegomarara padanho remasero, sekukura kwebundu, kupararira, uye kufa kwesero. Tichifunga izvi biological pesvedzero, kusarudza akakodzera anowedzera sePedra, ari ega kana musanganiswa, inova sarudzo yakakosha mumamiriro ehutano hwegomarara. Paunenge uchifunga kushandisa Pedra kwegomarara, zvakakosha kufunga izvi zvakasiyana siyana uye maitiro. Izvi zvinodaro nekuti, zvakafanana nekurapa cancer, kushandiswa kwePedra haisi sarudzo yepasirese yakakodzera vese vane cancer asi inoda kuve munhu.

Kusarudza Pedra Supplements

Kugadzirisa mubvunzo wekuti 'Ndirini pandinofanira kudzivisa Pedra mumamiriro ezvinhu eCancer' zvinonetsa nokuti mhinduro yacho ndeyemunhu oga - zvinongoreva 'Zvinoenderana!'. Zvakangofanana nemabatiro ekurapa kwegomarara anogona kusashanda kune wese murwere, kukosha uye kuchengetedzeka kana mabhenefiti ePedra anosiyana zvichienderana nemamiriro emunhu. Zvinhu zvakadai semhando chaiyo yegomarara, genetic predispositions, marapirwo azvino, mamwe ma supplements ari kutorwa, mararamiro ehupenyu, BMI, uye chero allergies zvese zvine basa mukuona kuti Pedra yakakodzera here kana kuti inofanira kudziviswa, zvichisimbisa kukosha kwekufunga kwemunhu zvisarudzo zvakadaro.

1. Ko Pedra Supplements ichabatsira here Primary Stomach signet ring cell carcinoma Varwere vari kurapwa Trifluridine?

Primary Dumbu sigineti ring cell carcinoma inoratidzwa nekumwe kushanduka kwemajini, zvinoti TTN, CSMD1 uye SLITRK2, izvo zvinotungamira kune shanduko mubiochemical nzira, kunyanya TGFB Chiratidzo. Kubudirira kwekurapwa kwegomarara, senge Trifluridine, zvinoenderana nemabatiro ayo ekuita pane idzi nzira. Iro zano rakakodzera rinosanganisira kuenzanisa chiito chekurapa nenzira dzinotyaira cancer, nekudaro kuve nechokwadi chemunhu uye nzira inoshanda. Mumamiriro ezvinhu akadai, kudzivirira chikafu kana kudya kunovaka muviri kunogona kupokana nemhedzisiro yekurapa kana kuderedza kurongeka uku kwakakosha. Semuyenzaniso, iyo Pedra yekuwedzera, iyo inobata iyo TGFB Signaling, inogona kunge isiri iyo sarudzo yakanaka munyaya yePrimary Stomach sigineti ring cell carcinoma kana ichiitwa Trifluridine. Izvi zvinodaro nekuti zvinogona kuwedzera kufambira mberi kwechirwere kana kukanganisa kushanda kwekurapa. Pakusarudza chirongwa chekudya, zvakakosha kuti utarise zvinhu zvakaita serudzi rwegomarara, marapirwo anoenderera mberi, zera, murume kana mukadzi, BMI, mararamiro, uye chero inozivikanwa genetic mutations.

2. Ko Pedra Supplements ichabatsira Varwere Vekutanga Mudumbu Adenocarcinoma vari kurapwa Oxaliplatin?

Primary Dumbu Adenocarcinoma inotaridzwa neakananga genetic mutations, seTP53, TTN uye PEG3, izvo zvinoguma nekuchinja mune biochemical nzira, kunyanya Extracellular Matrix Remodelling, Cell Cycle Checkpoints uye Apoptosis. Kushanda kwekurapa cancer, senge Oxaliplatin, kunotemerwa nekudyidzana kwayo nenzira idzi. Chinangwa ndechekuona kuti kurapwa kunoenderana nemakwara anotyaira cancer, achigonesa nzira yekurapa yemunhu. Muchirevo chechinyorwa chino, zvekudya kana zvekuwedzera zvinowirirana nekurapa kana kuwedzera kurongeka uku kunofanirwa kutariswa. Semuenzaniso, iyo Pedra yekuwedzera isarudzo ine musoro kune avo vane Primary Stomach Adenocarcinoma iri pasi peOxaliplatin. Izvi zvinodaro nekuti Pedra inokanganisa nzira dzakadai seExtracellular Matrix Remodelling, iyo inogona kuvharisa zvinhu zvinotyaira Primary Dumbu Adenocarcinoma kana kubatsira kushanda kweOxaliplatin.

3. Ko Pedra Supplements Yakachengeteka Kuvanhu Vane Utano Vane KMT2D Mutation Associated Genetic Risk?

Makambani akasiyana-siyana anopa gene mapaneru ekuongorora njodzi yemajini emhando dzakasiyana dzegomarara. Aya mapaneru anosanganisira majini akabatana nezamu, ovarian, uterine, prostate, uye gomarara remudumbu. Kuedza aya majini kunogona kusimbisa kuongororwa uye kuzivisa kurapwa uye manejimendi nzira. Kuziva musiyano unokonzera chirwere kunogona kubatsira mukuyedza uye kuongororwa kwehama dzinogona kunge dziri panjodzi. Iyo KMT2D gene inowanzobatanidzwa mune aya mapaneru ekuongorora njodzi yegomarara.

Kuchinja muKMT2D gene kunokanganisa nzira dzebiochemical kana maitiro, akadai seExtracellular Matrix Remodeling uye Oncogenic Histone Methylation, iyo inobatanidzwa zvakananga kana zvisina kunanga mukutyaira kenza padanho remamorekuru. Kana genetic panel ikaratidza shanduko muKMT2D ine chekuita nenjodzi yakawedzera yeBladder Urothelial Carcinoma, chikonzero chesainzi chinoratidza kudzivirira kushandiswa kwekuwedzera Pedra. Izvi zvinodaro nekuti kuwedzera Pedra kunopesvedzera nzira dzakaita seExtracellular Matrix Remodelling, izvo zvinogona kutungamira kune yakaipa mhedzisiro mumamiriro eiyo KMT2D shanduko uye ane hukama nekenza mamiriro.

4. Ko Pedra Supplements Yakachengeteka Kune Vanhu Vane Utano Vane ALK Mutation Associated Genetic Risk?

ALK inoita basa rakakosha mukuongorora njodzi yegomarara. Shanduko muALK inogona kukanganisa nzira dzakakosha dzebiochemical, kusanganisira MAPK Signaling uye Kukura Factor Signaling, iyo inokanganisa kukura kwegomarara. Kana genetic panel yako ichiratidzira shanduko muALK yakabatana neCentral Nervous System, funga kuisa Pedra supplement muchirongwa chako chekudya. Izvi zvinowedzera zvinogona kupesvedzera nzira dzakaita seMAPK Signaling, kubatsirwa nekupa rutsigiro rwakakodzera kune vanhu vane ALK mutations uye zvine chekuita nehutano.

Mhedziso

Zvinhu zviviri zvakakosha zvekuyeuka ndezvekuti marapirwo egomarara uye chikafu chinovaka muviri hazvina kumbofanana kune wese munhu. Zvokudya zvinovaka muviri, kusanganisira chikafu uye zvekuwedzera sePedra, chishandiso chinoshanda chinogona kudzorwa newe uchitarisana negomarara.

"Ndodyei?" ndiwo mubvunzo unonyanya kubvunzwa nevarwere vegomarara uye avo vari panjodzi yegomarara. Mhinduro chaiyo ndeyekuti zvinoenderana nezvinhu zvakaita serudzi rwegomarara, genetics yebundu, marapirwo azvino, allergies, mararamiro, uye BMI.

Tora kudya kwako kwegomarara kubva kuAddon nekudzvanya chinongedzo pazasi uye kupindura mibvunzo nezve rudzi rwegomarara rako, marapirwo, mararamiro, allergies, zera, uye murume kana mukadzi.

References

• cBioPortal yeCancer Genomics
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• cBioPortal yeCancer Genomics
• Comprehensive molecular characterization of gastric adenocarcinoma.
• Pan-cancer kuongororwa kweiyo genomes yakazara.
• Myrcene, Iyo Inonhuhwirira Volatile Compound, Inosimbisa Ganda Remunhu Extrinsic Kuchembera kuburikidza neRegulation yeMMPs Production.