Nderipi gomarara raizobatsirikana nekubatanidza Maral mukudya kwavo?

Muchidimbu

Maral inozivikanwa zvakanyanya nekuda kwehutano hwayo uye inowanzoshandiswa nevarwere vegomarara uye avo vari panjodzi yemajini. Asi, kuchengetedzeka uye kushanda kweMaral kune varwere vegomarara kunoenderana nezvinhu zvakawanda senge chiratidzo chegomarara, chemotherapy, kumwe kurapwa, uye genetics yebundu. Kuziva kuti zvimwe zvekudya uye zvekuwedzera, senge mazambiringa uye sipinachi, zvinogona kudyidzana zvisina kunaka nemishonga yekenza uye kukonzera kusawirirana kwakakosha.

Kudya kwakakosha pakurapwa kenza nekuti kunogona kukanganisa mhedzisiro yekurapa. Varwere vegomarara vanofanira kunyatsosarudza uye kuisa chikafu chakakodzera uye chekuwedzera mukudya kwavo. Semuenzaniso, Maral anogona kubatsira avo vane Primary Penile Squamous Cell Carcinoma vari pasi peMitomycin, asi zvingasava zvakanaka kune varwere vanogamuchira Irinotecan yePrimary Astrocytoma. Uyezve, nepo Maral achigona kubatsira vanhu vane genetic risk factor "ALK", inogona kunge isingakurudzirwe kune avo vane imwe genetic njodzi "KRAS". Kugadzirisa zvirongwa zvekudya zvinoenderana nehutano, kurapwa, uye genetics kwakakosha.

Kunzwisisa kuti kuita sarudzo pakukodzera kweMaral kune murwere wegomarara kunofanirwa kuve munhu mumwe kwakakosha. Zvinhu zvakakosha serudzi rwegomarara, nzira dzekurapa, genetic makeup, njodzi dzemajini, zera, uremu hwemuviri, uye mararamiro zvakakosha pakusarudza kana Maral iriyo sarudzo yakakodzera. Genetics uye genomics, kunyanya, inonyanya kutariswa. Sezvo zvinhu izvi zvichigona kushanduka, zvakakosha kuti ugare uchiongorora uye kugadzirisa sarudzo dzekudya kuti dzienderane nekuchinja kwehutano uye kurapwa.

Mukupedzisa, maitiro akazara esarudzo dzechikafu akakosha, tichitarisa pane zvese zvinokonzeresa zvese zvinoshanda zvinoringana muzvikafu / zvekuwedzera seMaral pachinzvimbo chekuongorora chega chega chega chega chega kana kufuratira zvachose. Maonero akafara aya anosimudzira nzira inonzwisisika uye yesainzi yekuronga kudya kwegomarara.

Pfupiso Pfupiso

Kushandiswa kwezvikafu zvakadyarwa nezvirimwa uye zvekuwedzera, senge mavhitamini, maruva, zvicherwa, probiotics, uye akasiyana siyana ekuwedzera, ari kuwedzera pakati pevarwere vegomarara. Izvi zvekuwedzera zvakagadzirirwa kuendesa yakakwira yakakwira yeaya anoshanda zvimisikidzo, mazhinji acho ari mukudya kwakasiyana. Iko kusungirirwa uye kusiyanisa kwezvinhu zvinoshanda zvinosiyana pakati pezvikafu zvese uye zvekuwedzera. Zvokudya zvinowanzopa huwandu hwezvinhu zvinoshanda asi pazvishoma zvakadzika, nepo ma supplements achipa huwandu hwepamusoro hwezvimwe zvinhu.

Tichifunga nezveakasiyana esainzi uye biological mabasa ega ega rinoshanda padanho remamorekuru, zvakakosha kuti uzvidavirire kune akasanganiswa mhedzisiro yezvikamu izvi kana uchifunga nezvechikafu uye chekuwedzera chekudya kana kusadya.

Mubvunzo wakaoma unomuka: Iwe unofanirwa here kubatanidza Maral mukudya kwako sechinhu chekudya kana chekuwedzera? Zvinokurudzirwa here kushandisa Maral kana iwe uine genetic predisposition kune cancer yakabatana neiyo ALK gene? Ko kana pachinzvimbo chako genetic njodzi ichibva kuKRAS gene? Zvinobatsira here kuisa Maral mukudya kwako kana waonekwa kuti une Primary Astrocytoma, kana kuti chirwere chako chiri Primary Penile Squamous Cell Carcinoma? Uyezve, manwiro ako eMaral anofanira kugadziriswa sei kana uri kurapwa neMitomycin kana chirongwa chako chekurapa chichibva kuMitomycin kuenda kuIrinotecan? Izvo zvakakosha kuti uzive kuti zvirevo zviri nyore senge 'Maral ndezvemusikirwo, saka zvinogara zvichibatsira' kana 'Maral inosimudzira kusadzivirirwa' hazvina kukwana pasarudzo dzekudya/zvekuwedzera.

Pamusoro pezvo, zvakakosha kuti uongorore zvakare kukodzera kwekusanganisira Maral mukudya kwako kana paine shanduko muchirongwa chako chekurapa. Muchidimbu, kana uchiita sarudzo nezve kubatanidza chikafu kana ma supplements seMaral mukudya kwako kune mabhenefiti ayo, iwe unofanirwa kufunga nezvese biochemical mhedzisiro yezvese zvinongedzo, uchifunga zvinhu zvakaita serudzi rwegomarara, marapirwo auri kuita, genetic predispositions. , uye sarudzo dzemararamiro.

kenza

Kenza inoramba iri dambudziko rakakura mune zvekurapa, kazhinji ichikonzera kunetseka kwakapararira. Nekudaro, kufambira mberi kwazvino kwakavandudza marapirwo ekurapa, kunyanya kuburikidza nemaitiro ekurapa emunhu, nzira dzisingapindire dzekutarisa uchishandisa ropa uye mate samples, uye kuvandudzwa kweimmunotherapy. Kuonekwa kwekutanga uye kupindira panguva yakakodzera kwave kwakakosha mukupesvedzera zvakanaka mhedzisiro yekurapa.

Kuongororwa kweGenetic kunopa vimbiso yakakosha mukuongorora njodzi yegomarara uye kukurumidza kutanga. Nekudaro, kune vanhu vazhinji vane mhuri uye genetic predispositions kugomarara, sarudzo dzekupindira kwekurapa, kunyangwe nekutarisa nguva dzose, kazhinji dzinogumira kana hapana. Kana ukangoonekwa uine imwe mhando yegomarara, yakadai sePrimary Penile Squamous Cell Carcinoma kana Primary Astrocytoma, nzira dzekurapa dzinofanirwa kugadziridzwa zvichienderana nebundu remunhu genetics, danho rechirwere, pamwe nezvinhu zvakaita sezera uye murume.

Mushure mekurapa, kuenderera mberi kwekutarisa kwakakosha kuti uone chero zviratidzo zvekenza kudzoka uye kuzivisa sarudzo dzinotevera. Vazhinji varwere vegomarara uye avo vari panjodzi vanowanzo tsvaga zano rekubatanidza zvimwe zvekudya uye zvekuwedzera mukudya kwavo, izvo zvinotora basa rakakosha mukuita kwavo kwese kwekuita sarudzo maererano nehutano hwehutano.

Mubvunzo wakaoma ndewekuti ungakonzeresa njodzi dzemajini uye negomarara rekuongororwa kana uchifunga nezvesarudzo dzekudya, senge Maral. Ko genetic njodzi yegomarara kubva mukushandurwa muALK ine zvakafanana biochemical nzira nzira sekuchinja muKRAS? Kubva pane zvinovaka muviri, njodzi inosanganisirwa nePrimary Penile Squamous Cell Carcinoma inofanana nePrimary Astrocytoma? Uyezve, kutariswa kwekudya kunoramba kwakafanana here kune avo vari pasi peIrinotecan kune avo vanogamuchira Mitomycin? Aya mafungidziro akakosha pakuita sarudzo dzechikafu kune vanhu vane njodzi dzakasiyana dzemajini uye marapirwo egomarara.

Maral – Mushonga Wekudya kunovaka muviri

Iyo yekuwedzera Maral inosanganisira huwandu hwezvinhu zvinoshanda, zvinosanganisira Ecdysterone, imwe neimwe iripo panguva dzakasiyana. Izvi zvinongedzo zvinopesvedzera mamorekuru nzira, kunyanya Lipid Metabolism uye Growth Factor Signaling, iyo inogadzirisa zvakakosha zvegomarara padanho remaserura, senge bundu kukura, kupararira, uye kufa kwesero. Tichifunga izvi biological pesvedzero, kusarudza akakodzera anowedzera seMaral, ari ega kana musanganiswa, inova sarudzo yakakosha mumamiriro ehutano hwegomarara. Paunenge uchifunga nezve kushandisa Maral yegomarara, zvakakosha kuti utarise izvi zvakasiyana zvinhu uye maitiro. Izvi zvinodaro nekuti, zvakafanana nekurapa cancer, kushandiswa kweMaral haisi sarudzo yepasirese yakakodzera vese vane cancer asi inoda kuve munhu.

Kusarudza Maral Supplements

Kutarisana nemubvunzo wekuti 'Ndirini pandinofanira kudzivisa Maral mumamiriro ezvinhu eCancer' zvinonetsa nokuti mhinduro yacho ndeyemunhu oga - zvinongoreva 'Zvinoenderana!'. Zvakafanana nemabatiro ekurapa kwegomarara anogona kusashanda kune wese murwere, kukosha uye kuchengetedzeka kana mabhenefiti eMaral anosiyana zvichienderana nemamiriro emunhu. Zvinhu zvakadai semhando chaiyo yegomarara, genetic predispositions, marapirwo azvino, mamwe ma supplements ari kutorwa, mararamiro, BMI, uye chero allergies zvese zvine basa mukuona kuti Maral akakodzera here kana kuti anofanirwa kudziviswa, zvichisimbisa kukosha kwekufunga kwemunhu. zvisarudzo zvakadaro.

1. Ko Maral Supplements ichabatsira Varwere vePrimary Astrocytoma vari kurapwa Irinotecan?

Primary Astrocytoma inoratidzwa neakanyanya genetic mutations, anoti NF1, PIK3CA uye TERT, izvo zvinotungamira kune shanduko munzira dzebiochemical, kunyanya Kukura Factor Signaling, MAPK Signaling, PI3K-AKT-MTOR Kuratidzira, Angiogenesis, Hematopoiesis, Cell Cycle Checkpoints uye Apop. Kubudirira kwekurapwa kwegomarara, senge Irinotecan, zvinoenderana nemabatiro ayo ekuita pane idzi nzira. Iro zano rakakodzera rinosanganisira kuenzanisa chiito chekurapa nenzira dzinotyaira cancer, nekudaro kuve nechokwadi chemunhu uye nzira inoshanda. Mumamiriro ezvinhu akadai, kudzivirira chikafu kana kudya kunovaka muviri kunogona kupokana nemhedzisiro yekurapa kana kuderedza kurongeka uku kwakakosha. Semuenzaniso, iyo Maral yekuwedzera, iyo inobata iyo Growth Factor Signaling, inogona kunge isiri iyo sarudzo yakanaka munyaya yePrimary Astrocytoma kana ichienda Irinotecan. Izvi zvinodaro nekuti zvinogona kuwedzera kufambira mberi kwechirwere kana kukanganisa kushanda kwekurapa. Pakusarudza chirongwa chekudya, zvakakosha kuti utarise zvinhu zvakaita serudzi rwegomarara, marapirwo anoenderera mberi, zera, murume kana mukadzi, BMI, mararamiro, uye chero inozivikanwa genetic mutations.

2. Ko Maral Supplements ichabatsira here Primary Penile Squamous Cell Carcinoma Varwere vari kurapwa Mitomycin?

Yekutanga Penile Squamous Cell Carcinoma inotaridzwa neyakajeka genetic mutations, senge ABRAXAS1, PIK3CB uye NUP93, izvo zvinokonzeresa shanduko mubiochemical nzira, kunyanya Lipid Metabolism, Hematopoiesis uye Inositol Phosphate Signaling. Kushanda kwekurapa kenza, seMitomycin, kunotemerwa nekudyidzana kwayo nenzira idzi. Chinangwa ndechekuona kuti kurapwa kunoenderana nemakwara anotyaira cancer, achigonesa nzira yemunhu yekurapa. Muchirevo chechinyorwa chino, zvikafu kana zvekuwedzera zvinowirirana nekurapa kana kuwedzera kurongeka uku kunofanirwa kutariswa. Semuyenzaniso, iyo Maral yekuwedzera isarudzo ine musoro kune avo vane Primary Penile Squamous Cell Carcinoma iri kuita Mitomycin. Izvi zvinodaro nekuti Maral inokanganisa nzira dzakadai seLipid Metabolism, iyo inogona kuvharisa zvinhu zvinotyaira Primary Penile Squamous Cell Carcinoma kana kubatsira kushanda kweMitomycin.

3. Ko Maral Supplements Yakachengeteka Kune Vane Hutano Vanhu Vane KRAS Mutation Associated Genetic Risk?

Makambani akasiyana-siyana anopa gene mapaneru ekuongorora njodzi yemajini emhando dzakasiyana dzegomarara. Aya mapaneru anosanganisira majini akabatana nezamu, ovarian, uterine, prostate, uye gomarara remudumbu. Kuedza aya majini kunogona kusimbisa kuongororwa uye kuzivisa kurapwa uye manejimendi nzira. Kuziva musiyano unokonzera chirwere kunogona kubatsira mukuyedza uye kuongororwa kwehama dzinogona kunge dziri panjodzi. Iyo KRAS gene inowanzobatanidzwa mune aya mapaneru ekuongorora njodzi yegomarara.

Shanduko muKRAS gene inokanganisa nzira dzebiochemical kana maitirwo, akadai seKukura Factor Signaling, MAPK Signaling, PI3K-AKT-MTOR Signaling uye RAS-RAF Signaling, ayo akabatanidzwa zvakananga kana zvisina kunanga mukutyaira cancer padanho remamorekuru. Kana genetic panel yakaratidza shanduko muKRAS ine chekuita nenjodzi yakawedzera yeCancer yeLung, chikonzero chesainzi chinoratidza kudzivirira kushandiswa kwekuwedzera Maral. Izvi zvinodaro nekuti kuwedzera kweMaral kunopesvedzera nzira dzakaita seKukura kweFactor Signaling, izvo zvinogona kutungamira kune yakaipa mhedzisiro mumamiriro ekuchinja kweKRAS uye ane chekuita nekenza mamiriro.

4. Ko Maral Supplements Yakachengeteka Kune Vanhu Vane Utano Vane ALK Mutation Associated Genetic Risk?

ALK inoita basa rakakosha mukuongorora njodzi yegomarara. Shanduko muALK inogona kukanganisa nzira dzakakosha dzebiochemical, kusanganisira Lipid Metabolism uye Kukura Factor Signaling, iyo inokanganisa kukura kwegomarara. Kana genetic panel yako ichiratidzira shanduko muALK yakabatana neCentral Nervous System, funga kuisa Maral supplement muchirongwa chako chekudya. Izvi zvinowedzera zvinogona kukanganisa nzira dzakadai seLipid Metabolism, kubatsirwa nekupa rubatsiro rwakakodzera kune vanhu vane ALK mutations uye zvinetso zvehutano zvine chokuita.

Mhedziso

Zvinhu zviviri zvakakosha zvekuyeuka ndezvekuti marapirwo egomarara uye chikafu chinovaka muviri hazvina kumbofanana kune wese munhu. Zvokudya zvinovaka muviri, kusanganisira chikafu uye zvekuwedzera senge Maral, chishandiso chinoshanda chinogona kudzorwa newe paunenge wakatarisana negomarara.

"Ndodyei?" ndiwo mubvunzo unonyanya kubvunzwa nevarwere vegomarara uye avo vari panjodzi yegomarara. Mhinduro chaiyo ndeyekuti zvinoenderana nezvinhu zvakaita serudzi rwegomarara, genetics yebundu, marapirwo azvino, allergies, mararamiro, uye BMI.

Tora kudya kwako kwegomarara kubva kuAddon nekudzvanya chinongedzo pazasi uye kupindura mibvunzo nezve rudzi rwegomarara rako, marapirwo, mararamiro, allergies, zera, uye murume kana mukadzi.

References

• Irinotecan kuramba inoperekedzwa nekusimudzirwa kweEGFR uye Src kusaina mumhando dzekenza yevanhu.
• cBioPortal yeCancer Genomics
• Mishonga yemakemikari yeMelandrium firmum Rohrbach uye basa ravo rinopesana nekuputika.
• Cancer therapy inoumba kusimba kwenzvimbo ye clonal hematopoiesis.
• Estrogen receptor beta inobatanidzwa mu skeletal muscle hypertrophy inokonzerwa ne phytoecdysteroid ecdysterone.
• Mutational landscape yekenza yemetastatic yakaratidzwa kubva kune vangangove vanotarisirwa kutevedzana kwevarwere zviuru gumi.
• [Cyclooxygenase-2 kutaura mune esophageal cancer maseru uye induction ne mitomycin C].