Nderipi gomarara raizobatsirwa nekubatanidza Feverfew mukudya kwavo?

Muchidimbu

Feverfew inozivikanwa zvakanyanya nekuda kwehutano hwayo uye inowanzoshandiswa nevarwere vegomarara uye avo vari panjodzi yemajini. Asi, kuchengetedzeka uye kushanda kweFeverfew yevarwere vegomarara kunoenderana nezvinhu zvakawanda senge chiratidzo chegomarara, chemotherapy, kumwe marapirwo, uye genetics yebundu. Kuziva kuti zvimwe zvekudya uye zvekuwedzera, senge mazambiringa uye sipinachi, zvinogona kudyidzana zvisina kunaka nemishonga yekenza uye kukonzera kusawirirana kwakakosha.

Kudya kwakakosha pakurapwa kenza nekuti kunogona kukanganisa mhedzisiro yekurapa. Varwere vegomarara vanofanira kunyatsosarudza uye nekubatanidza chikafu chakakodzera uye chekuwedzera mukudya kwavo. Semuenzaniso, Feverfew inogona kubatsira avo vane Primary Penile Squamous Cell Carcinoma vari pasi peMitomycin, asi zvingasava zvakanaka kune varwere vanogamuchira Pembrolizumab yePrimary Mucinous Stomach Adenocarcinoma. Uyezve, nepo Feverfew inogona kubatsira vanhu vane genetic risk factor "KIT", inogona kunge isingafungidzirwe kune avo vane imwe genetic njodzi "ASXL1". Kugadzirisa zvirongwa zvekudya zvinoenderana nehutano, kurapwa, uye genetics kwakakosha.

Kunzwisisa kuti kuita sarudzo pamusoro pekukodzera kweFeverfew kune murwere wegomarara kunofanirwa kuve munhu mumwe kwakakosha. Zvinhu zvakakosha serudzi rwegomarara, nzira dzekurapa, genetic makeup, njodzi dzemajini, zera, uremu hwemuviri, uye mararamiro zvakakosha pakusarudza kana Feverfew iriyo sarudzo yakakodzera. Genetics uye genomics, kunyanya, inonyanya kutariswa. Sezvo zvinhu izvi zvichigona kushanduka, zvakakosha kuti ugare uchiongorora uye kugadzirisa sarudzo dzekudya kuti dzienderane nekuchinja kwehutano uye kurapwa.

Mukupedzisa, maitiro akazara esarudzo dzekudya akakosha, tichitarisa pane zvese zvinokonzeresa zvese zvinoshanda zvinoringana muzvikafu / zvekuwedzera seFeverfew pachinzvimbo chekuongorora chega chega chega chega kana kufuratira zvachose. Maonero akafara aya anosimudzira nzira inonzwisisika uye yesainzi yekuronga kudya kwegomarara.

Pfupiso Pfupiso

Kushandiswa kwezvikafu zvakadyarwa nezvirimwa uye zvekuwedzera, senge mavhitamini, maruva, zvicherwa, probiotics, uye akasiyana siyana ekuwedzera, ari kuwedzera pakati pevarwere vegomarara. Izvi zvekuwedzera zvakagadzirirwa kuendesa yakakwira yakakwira yeaya anoshanda zvimisikidzo, mazhinji acho ari mukudya kwakasiyana. Iko kusungirirwa uye kusiyanisa kwezvinhu zvinoshanda zvinosiyana pakati pezvikafu zvese uye zvekuwedzera. Zvokudya zvinowanzopa huwandu hwezvinhu zvinoshanda asi pazvishoma zvakadzika, nepo ma supplements achipa huwandu hwepamusoro hwezvimwe zvinhu.

Tichifunga nezveakasiyana esainzi uye biological mabasa ega ega rinoshanda padanho remamorekuru, zvakakosha kuti uzvidavirire kune akasanganiswa mhedzisiro yezvikamu izvi kana uchifunga nezvechikafu uye chekuwedzera chekudya kana kusadya.

Mubvunzo wakaoma unomuka: Iwe unofanirwa here kuisa Feverfew mukudya kwako sechinhu chekudya kana chekuwedzera? Zvinokurudzirwa here kushandisa Feverfew kana uine genetic predisposition kune cancer yakabatana neKIT gene? Ko kana pachinzvimbo chako genetic njodzi ichibva kuASXL1 gene? Zvinobatsira here kuisa Feverfew mukudya kwako kana uchinge wabatwa nePrimary Mucinous Stomach Adenocarcinoma, kana kuti chirwere chako chiri Primary Penile Squamous Cell Carcinoma? Uyezve, manwiro ako eFeverfew anofanira kugadziriswa sei kana uri kurapwa neMitomycin kana chirongwa chako chekurapa chichibva kuMitomycin kuenda kuPembrolizumab? Izvo zvakakosha kuti uzive kuti zvirevo zviri nyore senge 'Feverfew ndezvakasikwa, saka zvinogara zvichibatsira' kana kuti 'Feverfew inowedzera kusadzivirirwa' hazvina kukwana pasarudzo dzechikafu/ dzekuwedzera.

Pamusoro pezvo, zvakakosha kuti uongorore zvakare kukodzera kwekubatanidza Feverfew mukudya kwako kana paine shanduko muchirongwa chako chekurapa. Muchidimbu, kana uchiita sarudzo dzekuisa chikafu kana ma supplements seFeverfew mukudya kwako nekuda kwemabhenefiti ayo, iwe unofanirwa kufunga nezvese biochemical mhedzisiro yezvese zvinongedzo, uchifunga nezvemhando dzakadai serudzi rwegomarara, marapirwo chaiwo auri kuita, genetic predispositions. , uye sarudzo dzemararamiro.

kenza

Kenza inoramba iri dambudziko rakakura mune zvekurapa, kazhinji ichikonzera kunetseka kwakapararira. Nekudaro, kufambira mberi kwazvino kwakavandudza marapirwo ekurapa, kunyanya kuburikidza nemaitiro ekurapa emunhu, nzira dzisingapindire dzekutarisa uchishandisa ropa uye mate samples, uye kuvandudzwa kweimmunotherapy. Kuonekwa kwekutanga uye kupindira panguva yakakodzera kwave kwakakosha mukupesvedzera zvakanaka mhedzisiro yekurapa.

Kuongororwa kweGenetic kunopa vimbiso yakakosha mukuongorora njodzi yegomarara uye kukurumidza kutanga. Nekudaro, kune vanhu vazhinji vane mhuri uye genetic predispositions kugomarara, sarudzo dzekupindira kwekurapa, kunyangwe nekutarisa nguva dzose, kazhinji dzinogumira kana hapana. Kana waonekwa kuti une imwe mhando yegomarara, yakadai sePrimary Penile Squamous Cell Carcinoma kana Primary Mucinous Stomach Adenocarcinoma, nzira dzekurapa dzinoda kugadziridzwa zvichienderana nebundu remunhu, danho rechirwere, pamwe nezvinhu zvakaita sezera uye murume kana mukadzi. ”

Mushure mekurapa, kuenderera mberi kwekutarisa kwakakosha kuti uone chero zviratidzo zvekenza kudzoka uye kuzivisa sarudzo dzinotevera. Vazhinji varwere vegomarara uye avo vari panjodzi vanowanzo tsvaga zano rekubatanidza zvimwe zvekudya uye zvekuwedzera mukudya kwavo, izvo zvinotora basa rakakosha mukuita kwavo kwese kwekuita sarudzo maererano nehutano hwehutano.

Mubvunzo wakaoma ndewekuti ungakonzeresa njodzi dzemajini uye negomarara chairo kana uchifunga nezvesarudzo dzekudya, senge Feverfew. Ko genetic njodzi yegomarara kubva mukushanduka muKIT ine zvakafanana biochemical nzira nzira sekuchinja muASXL1? Kubva pane zvinovaka muviri, njodzi inosanganisirwa nePrimary Penile Squamous Cell Carcinoma inofananidzwa nePrimary Mucinous Stomach Adenocarcinoma? Uyezve, kutariswa kwekudya kunoramba kwakafanana here kune avo vari kuita Pembrolizumab kune avo vanogamuchira Mitomycin? Aya mafungidziro akakosha pakuita sarudzo dzechikafu kune vanhu vane njodzi dzakasiyana dzemajini uye marapirwo egomarara.

Feverfew – A Nutritional Supplement

Iyo yekuwedzera Feverfew inosanganisa huwandu hwezvinhu zvinoshanda, zvinosanganisira Luteolin, Vitamin K, Centaureidin uye Parthenolide, yega yega iripo panguva dzakasiyana. Izvi zvinongedzo zvinopesvedzera nzira dzemamorekuru, kunyanya Extracellular Matrix Remodelling, WNT Beta Catenin Signaling, DNA Repair uye Oncogenic Cancer Epigenetics, iyo inotonga zvakakosha zvegomarara padanho remaserura, sekukura kwebundu, kupararira, uye kufa kwesero. Tichifunga izvi biological pesvedzero, kusarudza akakodzera anowedzera seFeverfew, ari ega kana musanganiswa, inova sarudzo yakakosha mumamiriro ehutano hwegomarara. Paunenge uchifunga kushandisa Feverfew yegomarara, zvakakosha kuti utarise izvi zvakasiyana-siyana zvinhu uye maitiro. Izvi zvinodaro nekuti, zvakafanana nekurapa gomarara, kushandiswa kweFeverfew haisi sarudzo yepasirese yakakodzera vese vane cancer asi inoda kuve munhu.

Kusarudza Feverfew Supplements

Kutarisana nemubvunzo wekuti 'Ndirini pandinofanira kudzivirira Feverfew mumamiriro ezvinhu eCancer' zvinonetsa nekuti mhinduro yacho ndeyemunhu mumwe chete - zvinongoreva 'Zvinoenderana!'. Zvakangofanana nemabatiro ekurapa kwegomarara anogona kusashanda kune wese murwere, kukosha uye kuchengetedzeka kana mabhenefiti eFeverfew anosiyana zvichienderana nemamiriro emunhu. Zvinhu zvakadai semhando chaiyo yegomarara, genetic predispositions, marapirwo azvino, mamwe ma supplements ari kutorwa, mararamiro, BMI, uye chero allergies zvese zvine basa mukuona kuti Feverfew yakakodzera here kana kuti inofanira kudziviswa, zvichisimbisa kukosha kwekufunga kwemunhu. zvisarudzo zvakadaro.

1. Ko Feverfew Supplements ichabatsira here Primary Mucinous Stomach Adenocarcinoma Varwere vari kurapwa Pembrolizumab?

Primary Mucinous Stomach Adenocarcinoma inoratidzwa nekumwe kushanduka kwemajini, anoti GRIN3A, TMEM26 uye TP53, izvo zvinotungamira kune shanduko mubiochemical nzira, kunyanya WNT Beta Catenin Signaling, Cell Cycle Checkpoints uye Apoptosis. Kubudirira kwekurapwa kwegomarara, senge Pembrolizumab, zvinoenderana nemabatiro ayo ekuita pane idzi nzira. Iro zano rakakodzera rinosanganisira kuenzanisa chiito chekurapa nenzira dzinotyaira cancer, nekudaro kuve nechokwadi chemunhu uye nzira inoshanda. Mumamiriro ezvinhu akadai, kudzivirira chikafu kana kudya kunovaka muviri kunogona kupokana nemhedzisiro yekurapa kana kuderedza kurongeka uku kwakakosha. Semuyenzaniso, iyo Feverfew yekuwedzera, iyo inobata iyo WNT Beta Catenin Signaling, inogona kunge isiri iyo sarudzo yakanaka munyaya yePrimary Mucinous Stomach Adenocarcinoma kana ichiitwa Pembrolizumab. Izvi zvinodaro nekuti zvinogona kuwedzera kufambira mberi kwechirwere kana kukanganisa kushanda kwekurapa. Pakusarudza chirongwa chekudya, zvakakosha kuti utarise zvinhu zvakaita serudzi rwegomarara, marapirwo anoenderera mberi, zera, murume kana mukadzi, BMI, mararamiro, uye chero inozivikanwa genetic mutations.

2. Ko Feverfew Supplements ichabatsira here Varwere vePenile Squamous Cell Carcinoma vari kurapwa neMitomycin?

Primary Penile Squamous Cell Carcinoma inotaridzwa neakananga genetic mutations, senge ABRAXAS1, PIK3CB uye NUP93, izvo zvinokonzeresa shanduko mubiochemical nzira, kunyanya Extracellular Matrix Remodelling, Hematopoiesis uye Inositol Phosphate Signaling. Kushanda kwekurapa kenza, seMitomycin, kunotemerwa nekudyidzana kwayo nenzira idzi. Chinangwa ndechekuona kuti kurapwa kunoenderana nemakwara anotyaira cancer, achigonesa nzira yemunhu yekurapa. Muchirevo chechinyorwa chino, zvekudya kana zvekuwedzera zvinowirirana nekurapa kana kuwedzera kurongeka uku kunofanirwa kutariswa. Semuenzaniso, iyo Feverfew yekuwedzera isarudzo ine musoro kune avo vane Primary Penile Squamous Cell Carcinoma iri pasi peMitomycin. Izvi zvinodaro nekuti Feverfew inokanganisa nzira dzakadai seExtracellular Matrix Remodelling, iyo inogona kutadzisa zvinhu zvinotyaira Primary Penile Squamous Cell Carcinoma kana kubatsira kushanda kweMitomycin.

3. Ko Feverfew Supplements Yakachengeteka Kune Vane Utano Vanhu Vane ASXL1 Mutation Associated Genetic Risk?

Makambani akasiyana-siyana anopa gene mapaneru ekuongorora njodzi yemajini emhando dzakasiyana dzegomarara. Aya mapaneru anosanganisira majini akabatana nezamu, ovarian, uterine, prostate, uye gomarara remudumbu. Kuedza aya majini kunogona kusimbisa kuongororwa uye kuzivisa kurapwa uye manejimendi nzira. Kuziva musiyano unokonzera chirwere kunogona kubatsira mukuyedza uye kuongororwa kwehama dzinogona kunge dziri panjodzi. Iyo ASXL1 gene inowanzo verengerwa mune aya mapaneru ekuongorora njodzi yegomarara.

Shanduko muASXL1 gene inokanganisa nzira dzebiochemical kana maitirwo, akadai seDNA Repair, Oncogenic Cancer Epigenetics uye Suppressive Histone Methylation, idzo dzakanangana kana zvisina kunanga kutyaira cancer padanho remamorekuru. Kana genetic panel yakaratidza shanduko muASXL1 yakabatana nenjodzi yakawedzera yeChronic Myelomonocytic Leukemia, chikonzero chesainzi chinoratidza kudzivirira kushandiswa kwekuwedzera Feverfew. Izvi zvinodaro nekuti yekuwedzera Feverfew inopesvedzera nzira dzakaita seDNA Kugadziriswa, izvo zvinogona kutungamira kune yakaipa mhedzisiro mumamiriro eiyo ASXL1 mutation uye ane hukama nekenza mamiriro.

4. Ko Feverfew Supplements Yakachengeteka Kune Vanhu Vane Utano Vane KIT Mutation Inobatanidza Genetic Risk?

KIT inoita basa rakakosha mukuongorora njodzi yegomarara. Shanduko muKIT inogona kukanganisa nzira dzakakomba dzebiochemical, kusanganisira Oncogenic Cancer Epigenetics uye Kukura Factor Signaling, iyo inokanganisa kukura kwegomarara. Kana yako genetic panel ikaratidza shanduko muKIT yakabatana neGastric Cancer, funga kuisa Feverfew supplement muchirongwa chako chekudya. Izvi zvinowedzera zvinogona kupesvedzera nzira dzakaita seOncogenic Cancer Epigenetics, kubatsirwa nekupa rutsigiro rwakakodzera kune vanhu vane KIT kuchinja uye zvine chekuita nehutano.

Mhedziso

Zvinhu zviviri zvakakosha zvekuyeuka ndezvekuti marapirwo egomarara uye chikafu chinovaka muviri hazvina kumbofanana kune wese munhu. Zvokudya zvinovaka muviri, kusanganisira chikafu uye zvekuwedzera senge Feverfew, chishandiso chinoshanda chinogona kudzorwa newe uchitarisana negomarara.

"Ndodyei?" ndiwo mubvunzo unonyanya kubvunzwa nevarwere vegomarara uye avo vari panjodzi yegomarara. Mhinduro chaiyo ndeyekuti zvinoenderana nezvinhu zvakaita serudzi rwegomarara, genetics yebundu, marapirwo azvino, allergies, mararamiro, uye BMI.

Tora kudya kwako kwegomarara kubva kuAddon nekudzvanya chinongedzo pazasi uye kupindura mibvunzo nezve rudzi rwegomarara rako, marapirwo, mararamiro, allergies, zera, uye murume kana mukadzi.

References

• cBioPortal yeCancer Genomics
• cBioPortal yeCancer Genomics
• Crystal chimiro chemunhu cyclin-inotsamira kinase 6 yakaoma ine flavonol inhibitor, fisetin.
• Inhibition ye hypoxia-induced epithelial mesenchymal transition ne luteolin mune isiri-diki cell kenza yemapapu maseru.
• Kubatanidzwa kwe integrinβ1 kunokonzeresa kuramba kwemasero egomarara redundiro kune mitomycin-C.
• Pan-cancer kuongororwa kweiyo genomes yakazara.
• Luteolin inokurudzira apoptotic cell death kuburikidza nekusimudzirwa kweNrf2 kutaura neDNA demethylase uye kusangana kweNrf2 ne p53 mumasero emukenza wekoloni.
• Immune activation uye mhinduro kune pembrolizumab muPOLE-mutant endometrial cancer.
• Cancer therapy inoumba kusimba kwenzvimbo ye clonal hematopoiesis.