Nderipi gomarara raizobatsirikana nekubatanidza Celandine mukudya kwavo?

Muchidimbu

Celandine inozivikanwa zvakanyanya nekuda kwehutano hwayo uye inowanzoshandiswa nevarwere vegomarara uye avo vari panjodzi yemajini. Asi, kuchengetedzeka uye kushanda kweCelandine yevarwere vegomarara kunoenderana nezvinhu zvakawanda senge chiratidzo chegomarara, chemotherapy, kumwe kurapwa, uye genetics yebundu. Kuziva kuti zvimwe zvekudya uye zvekuwedzera, senge mazambiringa uye sipinashi, zvinogona kupindirana zvisina kunaka nemishonga yekenza uye kukonzera kusawirirana kwakakosha.

Kudya kwakakosha pakurapwa kenza nekuti kunogona kukanganisa mhedzisiro yekurapa. Varwere vegomarara vanofanira kunyatsosarudza uye nekubatanidza chikafu chakakodzera uye chekuwedzera mukudya kwavo. Semuenzaniso, Celandine inogona kubatsira avo vane Primary Penile Squamous Cell Carcinoma vari pasi peMitomycin. Uyezve, nepo Celandine inogona kubatsira vanhu vane genetic risk factor "CDH1", inogona kunge isingafungidzirwe kune avo vane imwe genetic ngozi "ASXL1". Kugadzirisa zvirongwa zvekudya zvinoenderana nehutano, kurapwa, uye genetics kwakakosha.

Kunzwisisa kuti kuita sarudzo pakukodzera kweCelandine kune murwere wegomarara kunofanirwa kuve munhu mumwe kwakakosha. Zvinhu zvakakosha serudzi rwegomarara, nzira dzekurapa, genetic makeup, genetic njodzi, zera, uremu hwemuviri, uye mararamiro zvakakosha pakusarudza kana Celandine iriyo sarudzo yakakodzera. Genetics uye genomics, kunyanya, inonyanya kutariswa. Sezvo zvinhu izvi zvichigona kushanduka, zvakakosha kuti ugare uchiongorora uye kugadzirisa sarudzo dzekudya kuti dzienderane nekuchinja kwehutano uye kurapwa.

Mukupedzisa, nzira yakasarudzika yesarudzo yekudya yakakosha, kutarisa kune yakazara mhedzisiro yezvinhu zvese zvinoshanda muzvokudya / zvinowedzera seCelandine panzvimbo yekuongorora imwe neimwe inoshanda musanganiswa kana kuifuratira zvachose. Maonero akafara aya anosimudzira nzira inonzwisisika uye yesainzi yekuronga kudya kwegomarara.

Pfupiso Pfupiso

Kushandiswa kwezvikafu zvakadyarwa nezvirimwa uye zvekuwedzera, senge mavhitamini, maruva, zvicherwa, probiotics, uye akasiyana siyana ekuwedzera, ari kuwedzera pakati pevarwere vegomarara. Izvi zvekuwedzera zvakagadzirirwa kuendesa yakakwira yakakwira yeaya anoshanda zvimisikidzo, mazhinji acho ari mukudya kwakasiyana. Iko kusungirirwa uye kusiyanisa kwezvinhu zvinoshanda zvinosiyana pakati pezvikafu zvese uye zvekuwedzera. Zvokudya zvinowanzopa huwandu hwezvinhu zvinoshanda asi pazvishoma zvakadzika, nepo ma supplements achipa huwandu hwepamusoro hwezvimwe zvinhu.

Tichifunga nezveakasiyana esainzi uye biological mabasa ega ega rinoshanda padanho remamorekuru, zvakakosha kuti uzvidavirire kune akasanganiswa mhedzisiro yezvikamu izvi kana uchifunga nezvechikafu uye chekuwedzera chekudya kana kusadya.

Mubvunzo wakaoma unomuka: Iwe unofanirwa here kuisa Celandine mukudya kwako sechinhu chekudya kana chekuwedzera? Zvinokurudzirwa here kushandisa Celandine kana uine genetic predisposition kune cancer yakabatana neCDH1 gene? Ko kana pachinzvimbo chako genetic njodzi ichibva kuASXL1 gene? Zvinobatsira here kuisa Celandine mukudya kwako kana ukabatwa nePrimary Penile Squamous Cell Carcinoma? Uyezve, manwiro ako eCelandine anofanira kugadziriswa sei kana uri kurapwa neMitomycin kana chirongwa chako chekurapa chichibva kuMitomycin? Izvo zvakakosha kuti uzive kuti zvirevo zviri nyore senge 'Celandine ndeyechisikigo, saka zvinogara zvichibatsira' kana 'Celandine inosimudzira kusadzivirirwa' hazvina kukwana kune ruzivo rwechikafu / chekuwedzera sarudzo.

Pamusoro pezvo, zvakakosha kuti uongorore zvakare kukodzera kwekusanganisira Celandine mukudya kwako kana paine shanduko muchirongwa chako chekurapa. Muchidimbu, kana uchiita sarudzo nezve kubatanidza chikafu kana ma supplements seCelandine mukudya kwako kune mabhenefiti ayo, iwe unofanirwa kufunga nezvese biochemical mhedzisiro yezvese zvinongedzo, uchifunga zvinhu zvakaita serudzi rwegomarara, marapirwo auri kuita, genetic predispositions. , uye sarudzo dzemararamiro.

kenza

Kenza inoramba iri dambudziko rakakura mune zvekurapa, kazhinji ichikonzera kunetseka kwakapararira. Nekudaro, kufambira mberi kwazvino kwakavandudza marapirwo ekurapa, kunyanya kuburikidza nemaitiro ekurapa emunhu, nzira dzisingapindire dzekutarisa uchishandisa ropa uye mate samples, uye kuvandudzwa kweimmunotherapy. Kuonekwa kwekutanga uye kupindira panguva yakakodzera kwave kwakakosha mukupesvedzera zvakanaka mhedzisiro yekurapa.

Kuongororwa kweGenetic kunopa vimbiso yakakosha mukuongorora njodzi yegomarara uye kukurumidza kutanga. Nekudaro, kune vanhu vazhinji vane mhuri uye genetic predispositions kugomarara, sarudzo dzekupindira kwekurapa, kunyangwe nekutarisa nguva dzose, kazhinji dzinogumira kana hapana. Kana ukangoonekwa uine imwe mhando yegomarara, sePrimary Penile Squamous Cell Carcinoma, nzira dzekurapa dzinofanirwa kugadziridzwa zvichienderana nebundu remunhu, danho rechirwere, pamwe nezvinhu zvakaita sezera uye murume.

Mushure mekurapa, kuenderera mberi kwekutarisa kwakakosha kuti uone chero zviratidzo zvekenza kudzoka uye kuzivisa sarudzo dzinotevera. Vazhinji varwere vegomarara uye avo vari panjodzi vanowanzo tsvaga zano rekubatanidza zvimwe zvekudya uye zvekuwedzera mukudya kwavo, izvo zvinotora basa rakakosha mukuita kwavo kwese kwekuita sarudzo maererano nehutano hwehutano.

Mubvunzo wakaoma ndewekuti ungakonzeresa njodzi dzemajini uye negomarara rekuongororwa kana uchifunga nezvesarudzo dzekudya, senge Celandine. Ko genetic njodzi yegomarara kubva mukuchinjika muCDH1 ine zvakafanana biochemical nzira nzira sekuchinja muASXL1? Kubva pane zvinovaka muviri, njodzi inosanganisirwa nePrimary Penile Squamous Cell Carcinoma yakafanana nemamwe magomarara here? Uyezve, kufunga nezvekudya kunoramba kwakafanana kune avo vari kurapwa kumwe kune avo vanogamuchira Mitomycin? Aya mafungidziro akakosha pakuita sarudzo dzechikafu kune vanhu vane njodzi dzakasiyana dzemajini uye marapirwo egomarara.

Celandine - Mushonga weKudya

Iyo yekuwedzera Celandine inosanganisira huwandu hwezvinhu zvinoshanda, zvinosanganisira Chelidonine uye Chelerythrine, imwe neimwe iripo panguva dzakasiyana. Izvi zvinongedzo zvinopesvedzera nzira dzemamorekuru, kunyanya NFKB Signaling, DNA Repair uye Adherens junction, iyo inoronga zvakakomba zvegomarara padanho remasero, senge bundu kukura, kupararira, uye kufa kwesero. Tichifunga izvi biological pesvedzero, kusarudza akakodzera anowedzera seCelandine, ari ega kana musanganiswa, inova sarudzo yakakosha mumamiriro ehutano hwegomarara. Paunenge uchifunga kushandisa Celandine yegomarara, zvakakosha kuti utarise izvi zvakasiyana-siyana zvinhu uye maitiro. Izvi zvinodaro nekuti, zvakafanana nekurapa cancer, kushandiswa kweCelandine haisi sarudzo yepasirese yakakodzera vese vane cancer asi inoda kuve munhu.

Kusarudza Celandine Supplements

Kugadzirisa mubvunzo wekuti 'Ndirini pandinofanira kudzivirira Celandine mumamiriro ezvinhu eCancer' zvinonetsa nokuti mhinduro yacho ndeyemunhu oga - zvinongoreva 'Zvinoenderana!'. Zvakafanana nemabatiro ekurapa kwegomarara anogona kusashanda kune wese murwere, kukosha uye kuchengetedzeka kana mabhenefiti eCelandine anosiyana zvichienderana nemamiriro emunhu. Zvinhu zvakadai semhando chaiyo yegomarara, genetic predispositions, marapirwo azvino, mamwe ma supplements ari kutorwa, mararamiro, BMI, uye chero allergies zvese zvine basa mukuona kuti Celandine yakakodzera here kana kuti inofanira kudziviswa, zvichisimbisa kukosha kwekufunga kwemunhu. zvisarudzo zvakadaro.

1. Ko Celandine Supplements ichabatsira here Primary Penile Squamous Cell Carcinoma Varwere vari kurapwa Mitomycin?

Yekutanga Penile Squamous Cell Carcinoma inotaridzwa neyakajeka genetic mutations, seABRAXAS1, PIK3CB uye NUP93, izvo zvinokonzeresa shanduko mubiochemical nzira, kunyanya NFKB Signaling, Hematopoiesis uye Inositol Phosphate Signaling. Kushanda kwekurapa kenza, seMitomycin, kunotemerwa nekudyidzana kwayo nenzira idzi. Chinangwa ndechekuona kuti kurapwa kunoenderana nemakwara anotyaira cancer, achigonesa nzira yemunhu yekurapa. Muchirevo chechinyorwa chino, zvikafu kana zvekuwedzera zvinowirirana nekurapa kana kuwedzera kurongeka uku kunofanirwa kutariswa. Semuenzaniso, iyo Celandine yekuwedzera isarudzo ine musoro kune avo vane Primary Penile Squamous Cell Carcinoma iri pasi peMitomycin. Izvi zvinodaro nekuti Celandine inokanganisa nzira dzakadai seNFKB Signaling, inogona kuvharisa zvinhu zvinotyaira Primary Penile Squamous Cell Carcinoma kana kubatsira kushanda kweMitomycin.

2. Ko Celandine Supplements Yakachengeteka Kune Vane Utano Vanhu vane ASXL1 Mutation Associated Genetic Risk?

Makambani akasiyana-siyana anopa gene mapaneru ekuongorora njodzi yemajini emhando dzakasiyana dzegomarara. Aya mapaneru anosanganisira majini akabatana nezamu, ovarian, uterine, prostate, uye gomarara remudumbu. Kuedza aya majini kunogona kusimbisa kuongororwa uye kuzivisa kurapwa uye manejimendi nzira. Kuziva musiyano unokonzera chirwere kunogona kubatsira mukuyedza uye kuongororwa kwehama dzinogona kunge dziri panjodzi. Iyo ASXL1 gene inowanzo verengerwa mune aya mapaneru ekuongorora njodzi yegomarara.

Shanduko muASXL1 gene inokanganisa nzira dzebiochemical kana maitiro, akadai seDNA Repair, Oncogenic Cancer Epigenetics uye Suppressive Histone Methylation, idzo dzakanangana kana zvisina kunanga kutyaira cancer padanho remamorekuru. Kana genetic panel yakaratidza shanduko muASXL1 yakabatana nenjodzi yakawedzera yeChronic Myelomonocytic Leukemia, chikonzero chesainzi chinoratidza kudzivirira kushandiswa kwekuwedzera Celandine. Izvi zvinodaro nekuti kuwedzera Celandine kunopesvedzera nzira dzakaita seDNA Kugadzirisa, izvo zvinogona kutungamira kune yakaipa mhedzisiro mumamiriro eiyo ASXL1 mutation uye ane hukama nekenza mamiriro.

3. Ko Celandine Supplements Yakachengeteka Kune Vanhu Vane Utano Vane CDH1 Mutation Associated Genetic Risk?

CDH1 inobata basa rakakosha mukuongorora njodzi yegomarara. Kuchinja muCDH1 kunogona kukanganisa nzira dzakakosha dzebiochemical, kusanganisira Adherens junction uye Epithelial kuMesenchymal Transition, iyo inokonzera kukura kwegomarara. Kana genetic panel yako ikaratidza shanduko muCDH1 yakabatana neGastric Cancer, funga kuisa Celandine supplement muchirongwa chako chekudya. Izvi zvinowedzera zvinogona kupesvedzera nzira dzakaita seAdherens junction, kubatsirwa nekupa rubatsiro rwakakodzera kune vanhu vane CDH1 shanduko uye zvine chekuita nehutano.

Mhedziso

Zvinhu zviviri zvakakosha zvekuyeuka ndezvekuti marapirwo egomarara uye chikafu chinovaka muviri hazvina kumbofanana kune wese munhu. Zvokudya zvinovaka muviri, kusanganisira chikafu uye zvinowedzera seCelandine kune mabhenefiti ayo, chishandiso chinoshanda chinogona kudzorwa newe uchitarisana negomarara.

"Ndodyei?" ndiwo mubvunzo unonyanya kubvunzwa nevarwere vegomarara uye avo vari panjodzi yegomarara. Mhinduro chaiyo ndeyekuti zvinoenderana nezvinhu zvakaita serudzi rwegomarara, genetics yebundu, marapirwo azvino, allergies, mararamiro, uye BMI.

Tora kudya kwako kwegomarara kubva kuAddon nekudzvanya chinongedzo pazasi uye kupindura mibvunzo nezve rudzi rwegomarara rako, marapirwo, mararamiro, allergies, zera, uye murume kana mukadzi.

References

• cBioPortal yeCancer Genomics
• Cancer therapy inoumba kusimba kwenzvimbo ye clonal hematopoiesis.
• Chelidonine inodzvinyirira LPS-Induced kugadzirwa kwevamiririri vanovhiringidza kuburikidza nekudzivisa kweTLR4 / NF-κB nzira yekucherechedza muRAW264.7 macrophages.
• Chelidonine inowedzera antitumor mhedzisiro ye lenvatinib pane hepatocellular carcinoma masero.
• Piperine (PP) yakagadziridzwa mitomycin-C (MMC) kurapwa kwegomarara remuchibereko chemunhu kuburikidza nekudzvanya nzira yechiratidzo yeBcl-2 kuburikidza nekusaita STAT3/NF-κB.