Nderipi gomarara raizobatsirwa nekubatanidza Broccoli mukudya kwavo?

Muchidimbu

Broccoli inozivikanwa zvakanyanya nekuda kwehutano hwayo uye inowanzoshandiswa nevarwere vegomarara uye avo vari panjodzi yemajini. Asi, kuchengetedzeka uye kushanda kweBroccoli yevarwere vegomarara kunoenderana nezvinhu zvakawanda senge chiratidzo chegomarara, chemotherapy, kumwe kurapwa, uye genetics yebundu. Kuziva kuti zvimwe zvekudya uye zvekuwedzera, senge mazambiringa uye sipinachi, zvinogona kudyidzana zvisina kunaka nemishonga yekenza uye kukonzera kusawirirana kwakakosha.

Kudya kwakakosha pakurapwa kenza nekuti kunogona kukanganisa mhedzisiro yekurapa. Varwere vegomarara vanofanira kunyatsosarudza uye nekubatanidza chikafu chakakodzera uye chekuwedzera mukudya kwavo. Semuenzaniso, Broccoli inogona kubatsira avo vane Primary Solitary Fibrous Tumor vari pasi peAvastin, asi zvingasava zvakanaka kune varwere vanowana Gemcitabine yePrimary Sarcomoid Carcinoma yeUrinary Bladder. Uyezve, nepo Broccoli inogona kubatsira vanhu vane genetic risk factor "ASXL1", inogona kunge isingafungidzirwe kune avo vane imwe genetic njodzi "ALK". Kugadzirisa zvirongwa zvekudya zvinoenderana nehutano, kurapwa, uye genetics kwakakosha.

Kunzwisisa kuti kuita sarudzo pakukodzera kweBroccoli kune murwere wegomarara kunofanirwa kuve munhu mumwe kwakakosha. Zvinhu zvakakosha serudzi rwegomarara, nzira dzekurapa, genetic makeup, genetic njodzi, zera, uremu hwemuviri, uye mararamiro zvakakosha pakusarudza kana Broccoli iriyo sarudzo yakakodzera. Genetics uye genomics, kunyanya, inonyanya kutariswa. Sezvo zvinhu izvi zvichigona kushanduka, zvakakosha kuti ugare uchiongorora uye kugadzirisa sarudzo dzekudya kuti dzienderane nekuchinja kwehutano uye kurapwa.

Mukupedzisa, maitiro akazara esarudzo dzechikafu akakosha, achitarisa pane zvese zvinokonzeresa zvese zvinoshanda zvinoringana muzvikafu/zvinowedzera zvakaita seBroccoli pachinzvimbo chekuongorora chega chega chega chega chega kana kufuratira zvachose. Maonero akafara aya anosimudzira nzira inonzwisisika uye yesainzi yekuronga kudya kwegomarara.

Pfupiso Pfupiso

Kushandiswa kwezvikafu zvakadyarwa nezvirimwa uye zvekuwedzera, senge mavhitamini, maruva, zvicherwa, probiotics, uye akasiyana siyana ekuwedzera, ari kuwedzera pakati pevarwere vegomarara. Izvi zvekuwedzera zvakagadzirirwa kuendesa yakakwira yakakwira yeaya anoshanda zvimisikidzo, mazhinji acho ari mukudya kwakasiyana. Iko kusungirirwa uye kusiyanisa kwezvinhu zvinoshanda zvinosiyana pakati pezvikafu zvese uye zvekuwedzera. Zvokudya zvinowanzopa huwandu hwezvinhu zvinoshanda asi pazvishoma zvakadzika, nepo ma supplements achipa huwandu hwepamusoro hwezvimwe zvinhu.

Tichifunga nezveakasiyana esainzi uye biological mabasa ega ega rinoshanda padanho remamorekuru, zvakakosha kuti uzvidavirire kune akasanganiswa mhedzisiro yezvikamu izvi kana uchifunga nezvechikafu uye chekuwedzera chekudya kana kusadya.

Mubvunzo wakaoma unomuka: Iwe unofanirwa here kuisa Broccoli mukudya kwako sechinhu chekudya kana chekuwedzera? Zvinokurudzirwa here kushandisa Broccoli kana uine genetic predisposition kune cancer yakabatana neiyo ASXL1 gene? Zvakadini kana panzvimbo yako njodzi yemajini ichibva kune ALK gene? Zvinobatsira here kuisa Broccoli mukudya kwako kana ukawanikwa uine Primary Sarcomatoid Carcinoma yeUrinary Bladder, kana kuti chirwere chako chiri Primary Solitary Fibrous Tumor? Uyezve, manwiro ako eBroccoli anofanira kugadziriswa sei kana uri kurapwa neAvastin kana chirongwa chako chekurapa chichibva kuAvastin kuenda kuGemcitabine? Izvo zvakakosha kuti uzive kuti zvirevo zviri nyore senge 'Broccoli ndeyechisikigo, saka inogara inobatsira' kana 'Broccoli inosimudzira kusadzivirirwa' haina kukwana kune ruzivo rwechikafu/yekuwedzera sarudzo.

Pamusoro pezvo, zvakakosha kuti uongorore zvakare kukodzera kwekubatanidza Broccoli mukudya kwako kana paine shanduko muchirongwa chako chekurapa. Muchidimbu, kana uchiita sarudzo nezve kubatanidza chikafu kana ma supplements seBroccoli mukudya kwako kune mabhenefiti ayo, unofanirwa kufunga nezvese biochemical mhedzisiro yezvese zvinongedzo, uchifunga zvinhu zvakaita serudzi rwegomarara, marapirwo auri kuita, genetic predispositions. , uye sarudzo dzemararamiro.

kenza

Kenza inoramba iri dambudziko rakakura mune zvekurapa, kazhinji ichikonzera kunetseka kwakapararira. Nekudaro, kufambira mberi kwazvino kwakavandudza marapirwo ekurapa, kunyanya kuburikidza nemaitiro ekurapa emunhu, nzira dzisingapindire dzekutarisa uchishandisa ropa uye mate samples, uye kuvandudzwa kweimmunotherapy. Kuonekwa kwekutanga uye kupindira panguva yakakodzera kwave kwakakosha mukupesvedzera zvakanaka mhedzisiro yekurapa.

Kuongororwa kweGenetic kunopa vimbiso yakakosha mukuongorora njodzi yegomarara uye kukurumidza kutanga. Nekudaro, kune vanhu vazhinji vane mhuri uye genetic predispositions kugomarara, sarudzo dzekupindira kwekurapa, kunyangwe nekutarisa nguva dzose, kazhinji dzinogumira kana hapana. Kana waonekwa kuti une imwe mhando yegomarara, yakadai sePrimary Solitary Fibrous Tumor kana Primary Sarcomatoid Carcinoma yeUrinary Bladder, nzira dzekurapa dzinofanirwa kugadziridzwa zvichienderana nebundu remunhu genetics, danho rechirwere, pamwe nezvinhu zvakaita sezera uye. murume kana mukadzi.”

Mushure mekurapa, kuenderera mberi kwekutarisa kwakakosha kuti uone chero zviratidzo zvekenza kudzoka uye kuzivisa sarudzo dzinotevera. Vazhinji varwere vegomarara uye avo vari panjodzi vanowanzo tsvaga zano rekubatanidza zvimwe zvekudya uye zvekuwedzera mukudya kwavo, izvo zvinotora basa rakakosha mukuita kwavo kwese kwekuita sarudzo maererano nehutano hwehutano.

Mubvunzo wakaoma ndewekuti ungakonzeresa njodzi dzemajini uye negomarara rekuongororwa kana uchifunga nezvesarudzo dzekudya, seBroccoli. Ko genetic njodzi yegomarara kubva mukushanduka muASXL1 ine zvakafanana biochemical nzira nzira sekuchinja muALK? Kubva pane zvinovaka muviri, njodzi inosanganisirwa nePrimary Solitary Fibrous Tumor inofanana nePrimary Sarcomoid Carcinoma yeUrinary Bladder? Uyezve, kutariswa kwekudya kunoramba kwakafanana kune avo vari kuenda kuGemcitabine kune avo vanogamuchira Avastin? Aya mafungidziro akakosha pakuita sarudzo dzechikafu kune vanhu vane njodzi dzakasiyana dzemajini uye marapirwo egomarara.

Broccoli - A Nutritional Supplement

Iyo yekuwedzera Broccoli inosanganisira huwandu hwezvinhu zvinoshanda, zvinosanganisira Brassinin, Indole-3-carbinol, Vitamin A, Vitamin K uye Vitamin C, imwe neimwe iripo panguva dzakasiyana. Izvi zvinongedzo zvinopesvedzera nzira dzemamorekuru, kunyanya MYC Signaling uye PI3K-AKT-MTOR Signaling, iyo inoronga zvakakosha zvegomarara padanho remasero, sekukura kwebundu, kupararira, uye kufa kwesero. Tichifunga izvi biological pesvedzero, kusarudza iyo yakakodzera yekuwedzera seBroccoli, yega kana musanganiswa, inova sarudzo yakakosha mumamiriro ehutano hwegomarara. Paunenge uchifunga nezvekushandisa Broccoli yegomarara, zvakakosha kuti utarise izvi zvakasiyana zvinhu uye maitiro. Izvi zvinodaro nekuti, zvakafanana nekurapa cancer, kushandiswa kweBroccoli haisi sarudzo yepasirese yakakodzera vese vane cancer asi inoda kuve munhu.

Kusarudza Broccoli Supplements

Kutarisana nemubvunzo wekuti 'Ndirini pandinofanira kudzivisa Broccoli mumamiriro ezvinhu eCancer' zvinonetsa nokuti mhinduro yacho ndeyemunhu oga - zvinongoreva 'Zvinoenderana!'. Zvakangofanana nemabatiro ekurapa cancer anogona kusashanda kune wese murwere, kukosha uye kuchengetedzeka kana mabhenefiti eBroccoli anosiyana zvichienderana nemamiriro emunhu. Zvinhu zvakadai semhando chaiyo yegomarara, genetic predispositions, marapirwo azvino, zvimwe zvekuwedzera zviri kutorwa, mararamiro, BMI, uye chero allergies zvese zvine basa mukuona kuti Broccoli yakakodzera here kana kuti inofanira kudziviswa, zvichisimbisa kukosha kwekufunga kwemunhu zvisarudzo zvakadaro.

1. Ko Broccoli Supplements ichabatsira here Primary Sarcomatoid Carcinoma yeUrinary Bladder Patients vari kurapwa neGemcitabine?

Primary Sarcomatoid Carcinoma yeUrinary Bladder inoratidzwa nekumwe kushanduka kwemajini, anoti ERCC2, KRAS uye LATS2, izvo zvinotungamira kune shanduko munzira dzebiochemical nzira, kunyanya MYC Signaling, DNA Repair, Chromatin Remodeling, G-protein-coupled Receptor Signaling, Growth Factor Signal. neHippo Signaling. Kubudirira kwekurapwa kwegomarara, senge Gemcitabine, zvinoenderana nemaitiro ayo ekuita pane idzi nzira dzakananga. Iro zano rakakodzera rinosanganisira kuenzanisa chiito chekurapa nenzira dzinotyaira cancer, nekudaro kuve nechokwadi chemunhu uye nzira inoshanda. Mumamiriro ezvinhu akadai, kudzivirira chikafu kana kudya kunovaka muviri kunogona kupokana nemhedzisiro yekurapa kana kuderedza kurongeka uku kwakakosha. Semuyenzaniso, iyo Broccoli yekuwedzera, iyo inobata iyo MYC Signaling, inogona kunge isiri iyo sarudzo yakanaka munyaya yePrimary Sarcomoid Carcinoma yeUrinary Bladder kana uchiitwa Gemcitabine. Izvi zvinodaro nekuti zvinogona kuwedzera kufambira mberi kwechirwere kana kukanganisa kushanda kwekurapa. Pakusarudza chirongwa chekudya, zvakakosha kuti utarise zvinhu zvakaita serudzi rwegomarara, marapirwo anoenderera mberi, zera, murume kana mukadzi, BMI, mararamiro, uye chero inozivikanwa genetic mutations.

2. Ko Broccoli Supplements ichabatsira Varwere Vekutanga Vega Fibrous Tumor Varwere vari kurapwa neAvastin?

Primary Solitary Fibrous Tumor inotaridzwa neiyo chaiyo genetic mutations, senge BRD4, FLI1 uye KMT2C, izvo zvinoguma nekuchinja mune biochemical nzira, kunyanya MYC Signaling, Chromatin Remodeling, DNA Repair, Oncogenic Histone Methylation uye Amino Acid Metabolism. Kubudirira kwekurapwa kwegomarara, senge Avastin, kunotemerwa nekudyidzana kwayo nenzira idzi. Chinangwa ndechekuona kuti kurapwa kunoenderana nemakwara anotyaira cancer, achigonesa nzira yemunhu yekurapa. Muchirevo chechinyorwa chino, zvikafu kana zvekuwedzera zvinowirirana nekurapa kana kuwedzera kurongeka uku kunofanirwa kutariswa. Semuenzaniso, iyo Broccoli yekuwedzera isarudzo ine musoro kune avo vane Primary Solitary Fibrous Tumor iri pasi peAvastin. Izvi zvinodaro nekuti Broccoli inopesvedzera nzira dzakadai seMYC Signaling, inogona kuvharisa zvinhu zvinotyaira Primary Solitary Fibrous Tumor kana kubatsira kushanda kweAvastin.

3. Ko Broccoli Supplements Yakachengeteka Kune Vanhu Vane Utano Vane ALK Mutation Associated Genetic Risk?

Makambani akasiyana-siyana anopa gene mapaneru ekuongorora njodzi yemajini emhando dzakasiyana dzegomarara. Aya mapaneru anosanganisira majini akabatana nezamu, ovarian, uterine, prostate, uye gomarara remudumbu. Kuedza aya majini kunogona kusimbisa kuongororwa uye kuzivisa kurapwa uye manejimendi nzira. Kuziva musiyano unokonzera chirwere kunogona kubatsira mukuyedza uye kuongororwa kwehama dzinogona kunge dziri panjodzi. Iyo ALK gene inowanzobatanidzwa mune aya mapaneru ekuongorora njodzi yekenza.

Shanduko muAlK gene inokanganisa nzira dzebiochemical kana maitiro, akadai seMYC Signaling uye Growth Factor Signaling, ayo anobatanidzwa zvakananga kana zvisina kunanga mukutyaira cancer padanho remamorekuru. Kana genetic panel ikaratidza shanduko muALK yakabatana nenjodzi yakawedzera yeCentral Nervous System, chikonzero chesainzi chinoratidza kudzivirira kushandiswa kweBroccoli yekuwedzera. Izvi zvinodaro nekuti yekuwedzera Broccoli inopesvedzera nzira dzakaita seMYC Signaling, iyo inogona kutungamira kune yakaipa mhedzisiro mumamiriro eiyo ALK mutation uye ane hukama nekenza mamiriro.

4. Ko Broccoli Supplements Yakachengeteka Kune Vanhu Vane Utano Vane ASXL1 Mutation Associated Genetic Risk?

ASXL1 inoita basa rakakosha mukuongorora njodzi yegomarara. Shanduko muASXL1 inogona kukanganisa nzira dzakakosha dzebiochemical, kusanganisira PI3K-AKT-MTOR Chiratidzo, Oncogenic Cancer Epigenetics uye Suppressive Histone Methylation, iyo inokanganisa kukura kwegomarara. Kana yako genetic panel inoratidza shanduko muASXL1 yakabatana neChronic Myelomonocytic Leukemia, funga kuisa Broccoli yekuwedzera muchirongwa chako chekudya. Izvi zvinowedzera zvinogona kupesvedzera nzira dzakaita sePI3K-AKT-MTOR Signaling, kubatsirwa nekupa rubatsiro rwakakodzera kune vanhu vane ASXL1 shanduko uye zvine chekuita nehutano.

Mhedziso

Zvinhu zviviri zvakakosha zvekuyeuka ndezvekuti marapirwo egomarara uye chikafu chinovaka muviri hazvina kumbofanana kune wese munhu. Zvokudya zvinovaka muviri, kusanganisira chikafu uye zvekuwedzera seBroccoli, chishandiso chinoshanda chinogona kudzorwa newe uchitarisana negomarara.

"Ndodyei?" ndiwo mubvunzo unonyanya kubvunzwa nevarwere vegomarara uye avo vari panjodzi yegomarara. Mhinduro chaiyo ndeyekuti zvinoenderana nezvinhu zvakaita serudzi rwegomarara, genetics yebundu, marapirwo azvino, allergies, mararamiro, uye BMI.

Tora kudya kwako kwegomarara kubva kuAddon nekudzvanya chinongedzo pazasi uye kupindura mibvunzo nezve rudzi rwegomarara rako, marapirwo, mararamiro, allergies, zera, uye murume kana mukadzi.

References

• Mutational landscape yekenza yemetastatic yakaratidzwa kubva kune vangangove vanotarisirwa kutevedzana kwevarwere zviuru gumi.
• Triplex-inogadzira oligonucleotides yakananga c-MYC inogonesa iyo anti-tumor chiitiko chegemcitabine mune mbeva modhi yegomarara remunhu.
• cBioPortal yeCancer Genomics
• Kugadziriswazve kwePTEN tumor suppressor kurapwa kwegomarara kuburikidza nekuvharirwa kweMYC-WWP1 inhibitory nzira.
• cBioPortal yeCancer Genomics
• Brassinin induces G1 phase kusungwa kuburikidza nekuwedzera kwep21 uye p27 nekudzivirirwa kwephosphatidylinositol 3-kinase yekusaina nzira mumaseru ekenza yekoloni.
• Basa re tumor microenvironment mukupikisa anti-angiogenic therapy.