Nderipi gomarara raizobatsirwa nekubatanidza Atractylode mukudya kwavo?

Muchidimbu

Atractylode inozivikanwa zvakanyanya nekuda kwehutano hwayo uye inowanzoshandiswa nevarwere vegomarara uye avo vari panjodzi yemajini. Asi, kuchengetedzeka uye kushanda kweAtractylode yevarwere vegomarara kunoenderana nezvinhu zvakawanda senge chiratidzo chegomarara, chemotherapy, mamwe marapirwo, uye bundu genetics. Kuziva kuti zvimwe zvekudya uye zvekuwedzera, senge mazambiringa uye sipinachi, zvinogona kudyidzana zvisina kunaka nemishonga yekenza uye kukonzera kusawirirana kwakakosha.

Kudya kwakakosha pakurapwa kenza nekuti kunogona kukanganisa mhedzisiro yekurapa. Varwere vegomarara vanofanira kunyatsosarudza uye nekubatanidza chikafu chakakodzera uye chekuwedzera mukudya kwavo. Semuenzaniso, Atractylode inogona kubatsira avo vane Primary Esophageal Neuroendocrine Tumor iri pasi peRadiation, asi zvingasava zvakanaka kune varwere vanogamuchira Radiation yePrimary Urethral Squamous Cell Carcinoma. Uyezve, nepo Atractylode inogona kubatsira vanhu vane genetic risk factor "KMT2D", inogona kunge isingafungidzirwe kune avo vane genetic risk yakasiyana "ASXL1". Kugadzirisa zvirongwa zvekudya zvinoenderana nehutano, kurapwa, uye genetics kwakakosha.

Kunzwisisa kuti kuita sarudzo pakukodzera kweAtractylode yemurwere wegomarara kunofanirwa kuve munhu mumwe kwakakosha. Zvinhu zvakakosha serudzi rwegomarara, nzira dzekurapa, genetic makeup, genetic njodzi, zera, uremu hwemuviri, uye mararamiro zvakakosha pakusarudza kana Atractylode iriyo sarudzo yakakodzera. Genetics uye genomics, kunyanya, inonyanya kutariswa. Sezvo zvinhu izvi zvichigona kushanduka, zvakakosha kuti ugare uchiongorora uye kugadzirisa sarudzo dzekudya kuti dzienderane nekuchinja kwehutano uye kurapwa.

Mukupedzisa, nzira yakasarudzika yesarudzo yekudya yakakosha, ichitarisa kune yakazara mhedzisiro yezvinhu zvese zvinoshanda mukudya / zvinowedzera seAtractylode pachinzvimbo chekuongorora chega chega chega chega kana kuregeredza zvachose. Maonero akafara aya anosimudzira nzira inonzwisisika uye yesainzi yekuronga kudya kwegomarara.

Pfupiso Pfupiso

Kushandiswa kwezvikafu zvakadyarwa nezvirimwa uye zvekuwedzera, senge mavhitamini, maruva, zvicherwa, probiotics, uye akasiyana siyana ekuwedzera, ari kuwedzera pakati pevarwere vegomarara. Izvi zvekuwedzera zvakagadzirirwa kuendesa yakakwira yakakwira yeaya anoshanda zvimisikidzo, mazhinji acho ari mukudya kwakasiyana. Iko kusungirirwa uye kusiyanisa kwezvinhu zvinoshanda zvinosiyana pakati pezvikafu zvese uye zvekuwedzera. Zvokudya zvinowanzopa huwandu hwezvinhu zvinoshanda asi pazvishoma zvakadzika, nepo ma supplements achipa huwandu hwepamusoro hwezvimwe zvinhu.

Tichifunga nezveakasiyana esainzi uye biological mabasa ega ega rinoshanda padanho remamorekuru, zvakakosha kuti uzvidavirire kune akasanganiswa mhedzisiro yezvikamu izvi kana uchifunga nezvechikafu uye chekuwedzera chekudya kana kusadya.

Mubvunzo wakaoma unomuka: Iwe unofanirwa here kubatanidza Atractylode mukudya kwako sechinhu chekudya kana chekuwedzera? Zvinogoneka here kushandisa Atractylode kana uine genetic predisposition kune cancer yakabatana neKMT2D gene? Ko kana pachinzvimbo chako genetic njodzi ichibva kuASXL1 gene? Zvinobatsira here kuisa Atractylode mukudya kwako kana uchinge wabatwa nePrimary Urethral Squamous Cell Carcinoma, kana kuti chirwere chako chiri Primary Esophageal Neuroendocrine Tumor? Uyezve, mashandisiro ako eAtractylode anofanira kugadziriswa sei kana uri kurapwa neRadiation kana chirongwa chako chekurapa chichibva paRadiation kuenda kuRadiation? Izvo zvakakosha kuti uzive kuti zvirevo zviri nyore senge 'Atractylode ndeyechisikigo, saka inogara ichibatsira' kana 'Atractylode inosimudzira kusadzivirirwa' haina kukwana kune ruzivo rwechikafu/yekuwedzera sarudzo.

Pamusoro pezvo, zvakakosha kuti uongorore zvakare kukodzera kwekubatanidza Atractylode mukudya kwako kana paine shanduko muchirongwa chako chekurapa. Muchidimbu, kana uchiita sarudzo dzekuisa chikafu kana ma supplements seAtractylode mukudya kwako kune mabhenefiti ayo, unofanirwa kufunga nezvese biochemical mhedzisiro yezvese zvinongedzo, uchifunga nezvemhando dzakadai serudzi rwegomarara, marapirwo chaiwo auri kuita, genetic predispositions. , uye sarudzo dzemararamiro.

kenza

Kenza inoramba iri dambudziko rakakura mune zvekurapa, kazhinji ichikonzera kunetseka kwakapararira. Nekudaro, kufambira mberi kwazvino kwakavandudza marapirwo ekurapa, kunyanya kuburikidza nemaitiro ekurapa emunhu, nzira dzisingapindire dzekutarisa uchishandisa ropa uye mate samples, uye kuvandudzwa kweimmunotherapy. Kuonekwa kwekutanga uye kupindira panguva yakakodzera kwave kwakakosha mukupesvedzera zvakanaka mhedzisiro yekurapa.

Kuongororwa kweGenetic kunopa vimbiso yakakosha mukuongorora njodzi yegomarara uye kukurumidza kutanga. Nekudaro, kune vanhu vazhinji vane mhuri uye genetic predispositions kugomarara, sarudzo dzekupindira kwekurapa, kunyangwe nekutarisa nguva dzose, kazhinji dzinogumira kana hapana. Kana waonekwa kuti une imwe mhando yegomarara, sePrimary Esophageal Neuroendocrine Tumor kana Primary Urethral Squamous Cell Carcinoma, nzira dzekurapa dzinoda kugadziridzwa zvichienderana nebundu remunhu, danho rechirwere, pamwe nezvinhu zvakaita sezera uye murume kana mukadzi. ”

Mushure mekurapa, kuenderera mberi kwekutarisa kwakakosha kuti uone chero zviratidzo zvekenza kudzoka uye kuzivisa sarudzo dzinotevera. Vazhinji varwere vegomarara uye avo vari panjodzi vanowanzo tsvaga zano rekubatanidza zvimwe zvekudya uye zvekuwedzera mukudya kwavo, izvo zvinotora basa rakakosha mukuita kwavo kwese kwekuita sarudzo maererano nehutano hwehutano.

Mubvunzo wakaoma ndewekuti ungakonzeresa njodzi dzemajini uye negomarara rekuongororwa kana uchifunga nezvesarudzo dzekudya, senge Atractylode. Ko genetic njodzi yegomarara kubva mukushandurwa muKMT2D ine zvakafanana biochemical nzira nzira sekuchinja muASXL1? Kubva pane zvinovaka muviri, njodzi inosanganisirwa nePrimary Esophageal Neuroendocrine Tumor inofanana nePrimary Urethral Squamous Cell Carcinoma? Uyezve, kutariswa kwechikafu kunoramba kwakafanana here kune avo vari kuenda kuRadiation sekune avo vanogamuchira Radiation? Aya mafungidziro akakosha pakuita sarudzo dzechikafu kune vanhu vane njodzi dzakasiyana dzemajini uye marapirwo egomarara.

Atractylode – A Nutritional Supplement

Iyo yekuwedzera Atractylode inosanganisira huwandu hwezvinhu zvinoshanda, zvinosanganisira Syringin, Stigmasterol, Scopoletin, Protocatechuic Acid uye Palmitic Acid, imwe neimwe iripo panguva dzakasiyana. Izvi zvinongedzo zvinopesvedzera nzira dzemamorekuru, kunyanya MYC Signaling, DNA Repair, mRNA Splicing uye RAS-RAF Signaling, iyo inodzora zvinhu zvakakosha zvegomarara padanho remasero, sekukura kwebundu, kupararira, uye kufa kwesero. Tichifunga izvi biological pesvedzero, kusarudza akakodzera anowedzera seAtractylode, ari ega kana musanganiswa, inova sarudzo yakakosha mumamiriro ehutano hwegomarara. Paunenge uchifunga nezve kushandisa Atractylode yegomarara, zvakakosha kuti utarise izvi zvakasiyana zvinhu uye maitiro. Izvi zvinodaro nekuti, zvakafanana nekurapa cancer, kushandiswa kweAtractylode haisi sarudzo yepasirese yakakodzera vese vane cancer asi inoda kuve munhu.

Kusarudza Atractylode Supplements

Kugadzirisa mubvunzo wekuti 'Ndirini pandinofanira kudzivirira Atractylode mumamiriro eCancer' zvinonetsa nekuti mhinduro yacho ndeyemunhu mumwe chete - zvinongoreva 'Zvinoenderana!'. Zvakafanana nemabatiro ekurapa kwegomarara anogona kusashanda kune wese murwere, kukosha uye kuchengetedzeka kana mabhenefiti eAtractylode anosiyana zvichienderana nemamiriro emunhu. Zvinhu zvakadai semhando chaiyo yegomarara, genetic predispositions, marapirwo azvino, mamwe ma supplements ari kutorwa, mararamiro, BMI, uye chero allergies zvese zvine basa mukuona kuti Atractylode yakakodzera here kana kuti inofanira kudziviswa, zvichisimbisa kukosha kwekufunga kwemunhu zvisarudzo zvakadaro.

1. Ko Atractylode Supplements ichabatsira here Primary Urethral Squamous Cell Carcinoma Varwere vari kurapwa neRadiation?

Yekutanga Urethral Squamous Cell Carcinoma inoratidzwa nekumwe genetic mutations, iyo BLM, BRCA1 uye CTCF, izvo zvinotungamira kune shanduko mubiochemical nzira, kunyanya Androgen Signaling uye DNA Repair. Kubudirira kwekurapwa kwegomarara, senge Radiation, zvinoenderana nemaitiro ayo ekuita pane idzi nzira dzakananga. Iro zano rakakodzera rinosanganisira kuenzanisa chiito chekurapa nenzira dzinotyaira cancer, nekudaro kuve nechokwadi chemunhu uye nzira inoshanda. Mumamiriro ezvinhu akadai, kudzivirira chikafu kana kudya kunovaka muviri kunogona kupokana nemhedzisiro yekurapa kana kuderedza kurongeka uku kwakakosha. Semuyenzaniso, iyo Atractylode yekuwedzera, iyo inobata iyo DNA Kugadziriswa, inogona kunge isiri iyo sarudzo yakanaka munyaya yePrimary Urethral Squamous Cell Carcinoma kana ichiitwa neRadiation. Izvi zvinodaro nekuti zvinogona kuwedzera kufambira mberi kwechirwere kana kukanganisa kushanda kwekurapa. Pakusarudza chirongwa chekudya, zvakakosha kuti utarise zvinhu zvakaita serudzi rwegomarara, marapirwo anoenderera mberi, zera, murume kana mukadzi, BMI, mararamiro, uye chero inozivikanwa genetic mutations.

2. Ko Atractylode Supplements ichabatsira Primary Esophageal Neuroendocrine Tumor Varwere vari kurapwa neRadiation?

Primary Esophageal Neuroendocrine Tumor inotaridzwa neakananga genetic mutations, seTP53, RB1 uye APEX1, izvo zvinoguma nekuchinja kwebiochemical nzira, kunyanya MYC Signaling, Cell Cycle Checkpoints, Apoptosis uye DNA Repair. Kushanda kwekurapa cancer, seRadiation, kunotemerwa nekudyidzana kwayo nenzira idzi. Chinangwa ndechekuona kuti kurapwa kunoenderana nemakwara anotyaira cancer, achigonesa nzira yemunhu yekurapa. Muchirevo chechinyorwa chino, zvikafu kana zvekuwedzera zvinowirirana nekurapa kana kuwedzera kurongeka uku kunofanirwa kutariswa. Semuenzaniso, iyo Atractylode yekuwedzera isarudzo ine musoro kune avo vane Primary Esophageal Neuroendocrine Tumor iri kuita Radiation. Izvi zvinodaro nekuti Atractylode inopesvedzera nzira dzakadai seMYC Signaling, inogona kuvharisa zvinhu zvinotyaira Primary Esophageal Neuroendocrine Tumor kana kubatsira kushanda kweRadiation.

3. Ko Atractylode Supplements Yakachengeteka Kune Vane Utano Vanhu Vane ASXL1 Mutation Associated Genetic Risk?

Makambani akasiyana-siyana anopa gene mapaneru ekuongorora njodzi yemajini emhando dzakasiyana dzegomarara. Aya mapaneru anosanganisira majini akabatana nezamu, ovarian, uterine, prostate, uye gomarara remudumbu. Kuedza aya majini kunogona kusimbisa kuongororwa uye kuzivisa kurapwa uye manejimendi nzira. Kuziva musiyano unokonzera chirwere kunogona kubatsira mukuyedza uye kuongororwa kwehama dzinogona kunge dziri panjodzi. Iyo ASXL1 gene inowanzo verengerwa mune aya mapaneru ekuongorora njodzi yegomarara.

Shanduko muASXL1 gene inokanganisa nzira dzebiochemical kana maitiro, senge mRNA Splicing, Oncogenic Cancer Epigenetics uye Suppressive Histone Methylation, idzo dzakabatanidzwa zvakananga kana zvisina kunanga mukutyaira cancer padanho remamorekuru. Kana genetic panel yakaratidza shanduko muASXL1 yakabatana nenjodzi yakawedzera yeChronic Myelomonocytic Leukemia, chikonzero chesainzi chinoratidza kudzivirira kushandiswa kweAtractylode yekuwedzera. Izvi zvinodaro nekuti yekuwedzera Atractylode inopesvedzera nzira dzakaita semRNA Splicing, izvo zvinogona kutungamira kune yakaipa mhedzisiro mumamiriro eiyo ASXL1 mutation uye ane hukama nekenza mamiriro.

4. Ko Atractylode Supplements Yakachengeteka Kune Vanhu Vane Utano Vane KMT2D Mutation Associated Genetic Risk?

KMT2D inoita basa rakakosha mukuongorora njodzi yegomarara. Kuchinja muKMT2D kunogona kukanganisa nzira dzakakosha dzebiochemical, kusanganisira RAS-RAF Signaling uye Oncogenic Histone Methylation, iyo inokanganisa kukura kwegomarara. Kana genetic panel yako ikaratidza shanduko muKMT2D yakabatana neBladder Urothelial Carcinoma, funga kuisa Atractylode supplement muchirongwa chako chekudya. Izvi zvinowedzera zvinogona kupesvedzera nzira dzakaita seRAS-RAF Signaling, kubatsirwa nekupa rutsigiro rwakakodzera kune vanhu vane KMT2D shanduko uye zvine chekuita nehutano.

Mhedziso

Zvinhu zviviri zvakakosha zvekuyeuka ndezvekuti marapirwo egomarara uye chikafu chinovaka muviri hazvina kumbofanana kune wese munhu. Zvokudya zvinovaka muviri, kusanganisira chikafu uye zvekuwedzera senge Atractylode, chishandiso chinoshanda chinogona kudzorwa newe uchitarisana negomarara.

"Ndodyei?" ndiwo mubvunzo unonyanya kubvunzwa nevarwere vegomarara uye avo vari panjodzi yegomarara. Mhinduro chaiyo ndeyekuti zvinoenderana nezvinhu zvakaita serudzi rwegomarara, genetics yebundu, marapirwo azvino, allergies, mararamiro, uye BMI.

Tora kudya kwako kwegomarara kubva kuAddon nekudzvanya chinongedzo pazasi uye kupindura mibvunzo nezve rudzi rwegomarara rako, marapirwo, mararamiro, allergies, zera, uye murume kana mukadzi.

References

• A redox-resistant sirtuin-1 mutant inodzivirira kubva kune hepatic metabolic uye oxidant kusagadzikana.
• cBioPortal yeCancer Genomics
• Functional lipidomics: Palmitic acid inokanganisa hepatocellular carcinoma kukura nekugadzirisa membrane fluidity uye glucose metabolism.
• cBioPortal yeCancer Genomics
• Impact of oncogenic K-RAS paYB-1 phosphorylation inokonzerwa neionizing radiation.
• Mutational landscape yekenza yemetastatic yakaratidzwa kubva kune vangangove vanotarisirwa kutevedzana kwevarwere zviuru gumi.
• BRCA1 kutaura kunodzoreredza kuramba kwemwaranzi muBRCA1-yakakanganisika cancer maseru kuburikidza nekusimudzira kwekunyora-kwakabatana DNA kugadzirisa.