Zvokudya zveHemangioblastoma!

ziviso

Zvikafu zveHemangioblastoma zvinofanirwa kuve zvakasarudzika kune wega wega uye zvakare zvinofanirwa kuchinjika kana kenza kurapwa kana bundu genetic shanduko. Iyo yemunhu uye kugadzirisa kunofanirwa kufunga nezvese zvinoshanda zvinosanganiswa kana bioactives zviri muzvokudya zvakasiyana zvine chekuita negomarara biology, genetics, marapirwo, mararamiro uye zvido zvekudya. Saka nepo chikafu chiri chimwe chezvisarudzo zvakakosha zvemurwere wegomarara uye munhu ari panjodzi yegomarara - kusarudza chikafu chekudya harisi basa riri nyore.

Hemangioblastoma ibundu risina kenza (benign) rinokura mumutsara wetsinga yeropa, uye inoumba muchikamu chezasi cheuropi, musana, kana retina. Iwo mamota anokura zvishoma nezvishoma ayo anogona kazhinji kurapwa kusati kwaitika matambudziko asingaperi. Vanhu vazhinji vane shanduko mujini VHL (kana nevon Hippel-Lindau syndrome) vane mukana wakakura wekuita hemangioblastomas. Hemangioblastomas inowanzoitika kune vanhu vakuru pakati pemakore e20-65 ekuberekwa. Zviratidzo zve hemangioblastoma zvinogona kusiyana zvichienderana nenzvimbo yebundu uye inowanzokura zvishoma nezvishoma. Zviratidzo zvakajairika zvinosanganisira kutemwa nemusoro, kurasikirwa kwekubatana uye kuenzanisa, kusvotwa, kurutsa, kushaya simba kwetsandanyama kana kupera simba, kuvimbiswa, kusagadzikana. Radiosurgery ndiyo yakakosha sarudzo yekurapa hemangioblastomas. Kana yakabudirira kurapwa, haina matambudziko enguva refu uye kazhinji haidzokeri, asi kana hemangioblastoma yakakura uye yakakuvadza tsinga muuropi, panogona kuva nezvinetso zvenguva refu. Kutsigira kuchengetedza nekudya kwakakodzera (chikafu uye zvisikwa zvekuwedzera) zvinogona kuwedzera kubatsira nekuvandudza kugara kwevarwere.

Kune Hemangioblastoma zvine basa here kuti miriwo, michero, nzungu, mhodzi munhu anodya chii?

Mubvunzo wakajairika wekudya unobvunzwa nevarwere vegomarara uye vanhu vari pa-genetic njodzi yegomarara ndeye - kugomarara senge Hemangioblastoma zvine basa here kuti ndechipi chikafu chandinodya uye chandisingade? Kana kuti kana ndikatevera kudya-kwekudyara kunokwana kenza seHemangioblastoma?

Semuyenzaniso zvine basa here kana muriwo Bitter Gourd ukadyiwa zvakanyanya zvichienzaniswa neMasitadhi Sipinachi? Zvinoita mutsauko here kana muchero Pummelo uchifarirwa pane Red Raspberry? Zvakare kana sarudzo dzakafanana dzikaitirwa nzungu/mhodzi dzakaita seCommon Walnut pamusoro peMacadamia Nut uye nemapuruzi akaita seBroad Bean pamusoro peLima Bean. Uye kana izvo zvandinodya zvine basa - zvino munhu angaziva sei chikafu chinokurudzirwa kuHemangioblastoma uye ndiyo mhinduro imwechete kune wese ane chirwere chakafanana kana genetic njodzi?

Ehe! Zvokudya zvaunodya zvine chekuita neHemangioblastoma!

Mazano echikafu anogona kunge asina kufanana kune wese munhu uye anogona kuve akasiyana kunyangwe kune imwechete kuongororwa uye genetic njodzi.

Zvokudya zvose (miriwo, michero, nzungu, mhodzi, pulses, mafuta nezvimwewo) uye zvokudya zvinovaka muviri zvinoumbwa nezvinodarika imwe inoshanda mamolecular ingredient kana bio-actives muzvikamu zvakasiyana uye uwandu. Chinhu chimwe nechimwe chinoshanda chine nzira yakasarudzika yekuita - iyo inogona kuve activation kana inhibition yeakasiyana biochemical nzira. Zvikafu zvakangotaurwa uye zvekuwedzera izvo zvinokurudzirwa ndezviya zvisingakonzere kuwedzera kwemamorekuru anotyaira cancer asi anodzideredza. Zvikasadaro izvo zvikafu hazvifanirwe kukurudzirwa. Chikafu chine akawanda anoshanda zvinongedzo - saka kana uchiongorora chikafu uye zvekuwedzera iwe unofanirwa kufunga nezve mabatiro ezvese zvinoshanda zvinongedzo zvakapetwa kwete zvega.

Somuenzaniso Pummelo ine zvinhu zvinoshanda Quercetin, Catechol, Daidzein, Delphinidin, Isoliquiritigenin. Uye Red Raspberry ine inoshanda zvinoshandiswa Ellagic Acid, Quercetin, Catechol, Daidzein, Delphinidin uye pamwe nevamwe.

Chikanganiso chinowanzoitwa pakusarudza nekusarudza chikafu chekudya cheHemangioblastoma - kuongorora chete zvakasarudzwa zvinoshandiswa zviri muzvokudya uye kufuratira zvimwe. Nekuti zvakasiyana-siyana zvinoshanda zviri mukudya zvinogona kuva nemhedzisiro inopikisa kune vatyairi vegomarara - haugone kutora cherry inoshanda mukudya uye ma supplements ekuita sarudzo yehutano hweHemangioblastoma.

HONGU – ZVOKUSARUDZA ZVOKUDYA ZVINOKOSHA NEGONSA. ZVISARUDZO ZVOKUDYA ZVINOFANIRA KUFUNGA ZVINHU ZVINHU ZVINHU ZVINOSHANDA PACHIDYA.

Hunyanzvi hunodiwa paKudya Kwekudya Kwemunhu kune Hemangioblastoma?

Kudya kwakasarudzika kwegomarara senge Hemangioblastoma ine zvinokurudzirwa zvekudya / zvinowedzera; zvisingakurudzirwe chikafu / ma supplements ane semuenzaniso mabikirwo anotungamira kushandiswa kwezvikafu zvinokurudzirwa. Muenzaniso wekudya kwakasiyana-siyana unogona kuonekwa pane izvi batanidzo.

Kufunga kuti ndezvipi zvekudya zvinokurudzirwa kana kwete zvakaomesesa, zvinoda hunyanzvi muHemangioblastoma biology, sainzi yechikafu, genetics, biochemistry pamwe nekunzwisisa kwakanaka kwemashandiro anoita marapirwo egomarara uye kusagadzikana kwakabatana uko kurapwa kwaigona kumira kushanda.

ZVINONYANYA ZVINONYANYA ZVINODIWA KUTI ZVINOVAKA ZVINOVAKA MUNHU ZVINHU ZVINHU ZVINOITA: CANCER BIOLOGY, FOOD SCIENCE, KURAPA MAKANZA UYE GENETICS.

Hunhu hwegomarara senge Hemangioblastoma

Magomarara ese akaita seHemangioblastoma anogona kuratidzirwa neyakasiyana seti yebiochemical nzira - iyo siginecha nzira dzeHemangioblastoma. Biochemical pathways seAngiogenesis, MAPK Signaling, Hypoxia, DNA Repair chikamu chetsanangudzo siginecha yeHemangioblastoma. Kenza yemunhu wega genetics inogona kuve yakasiyana uye nekudaro siginicha yavo yegomarara inogona kuve yakasarudzika.

Kurapa kunoshanda kuHemangioblastoma kunoda kuziva nzira dzakasaina dzebiochemical yemurwere wega wega wegomarara uye munhu ari panjodzi yemagene. Saka marapirwo akasiyana ane maitiro akasiyana ezviito anoshanda kune varwere vakasiyana. Saizvozvo uye nekuda kwezvikonzero zvakafanana zvekudya uye zvekuwedzera zvinoda kuitirwa munhu wega wega. Saka zvimwe zvekudya uye zvekuwedzera zvinokurudzirwa kuHemangioblastoma kana uchitora kurapwa kenza Bevacizumab, uye zvimwe zvekudya uye zvekuwedzera hazvikurudzirwe.

Sources like cBioPortal uye vamwe vazhinji vanopa mumiriri wehuwandu hwevarwere data risingazivikanwe kubva kukiriniki miedzo yezvese zviratidzo zvegomarara. Iyi dhata ine yekiriniki yekuongorora yeruzivo senge sampuli saizi / nhamba yevarwere, mapoka ezera, murume kana mukadzi, dzinza, marapirwo, bundu saiti uye chero genetic mutations.

VHL, XPC, FUS, KDM6B uye TP53BP1 ndiwo mazita epamusoro akashumwa majini eHemangioblastoma. VHL inoshumwa mu58.6% yevanomiririra varwere mukati meyese miedzo yekiriniki. Uye XPC inoshumwa mu18.2%. Iyo yakasanganiswa yehuwandu hwevarwere data inovhara mazera kubva kusvika . 66.7% yedata revarwere vanoonekwa sevarume. Iyo Hemangioblastoma biology pamwe neyakashumwa genetics pamwe chete inotsanangura huwandu hwehuwandu hunomiririrwa siginecha biochemical nzira dzegomarara iri. Kana iyo yega cancer bundu genetics kana majini anokonzera njodzi achizivikanwa zvakare saka izvo zvinofanirwa kushandiswawo kune chikafu chemunhu.

ZVAKASARUDZA KUDYA ZVINODYA ZVINOFANIRA KUFANIRA NEMUNHU WEMUNHU WEMUNHU WEMUNHU WEGONSI.

Chikafu uye Zvekuwedzera zveHemangioblastoma

Kune Varwere veCancer

Varwere vegomarara vari pakurapa kana pakuchengeta palliative vanofanira kuita sarudzo pazvekudya uye zvekuwedzera - zvemacalorie anodiwa ekudya, kubata chero mhedzisiro yekurapa uyezve nekugadzirisa kenza. Zvese zvinodyarwa-zvikafu hazvina kuenzana uye kusarudza uye kuisa pamberi pezvikafu zvakagadzirirwa munhu uye zvakagadzirirwa kuenderera mberi kurapwa kwegomarara kwakakosha uye kwakaoma. Heano mimwe mienzaniso inopa nhungamiro yekuita sarudzo dzekudya.

Sarudza Vegetable BITTER GOURD kana MUSTARD SPINACH?

Vegetable Bitter Gourd ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seCatechol, Daidzein, Delphinidin, Isoliquiritigenin, Cinnamaldehyde. Izvi zvinoshanda zvinongedzo zvinoshandisa nzira dzakasiyana dzebiochemical seMAPK Signaling, Angiogenesis uye PI3K-AKT-MTOR Signaling nevamwe. Bitter Gourd inokurudzirwa kuHemangioblastoma kana iri kuramba ichirapwa gomarara iri Bevacizumab. Izvi zvinodaro nekuti Bitter Gourd inogadziridza idzo nzira dzebiochemical dzakataurwa nesainzi kuti dzikurudzire maitiro eBevacizumab.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuriwo Mustard Sipinachi iCatechol, Daidzein, Delphinidin, Isoliquiritigenin, Cinnamaldehyde. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seTGFB Signaling uye PI3K-AKT-MTOR Signaling nevamwe. Mustard Sipinachi haikurudzirwe kuHemangioblastoma kana ichienderera mberi kurapwa kwegomarara iri Bevacizumab nekuti inogadzirisa idzo biochemical nzira dzinoita kuti kurapwa kwegomarara kurambe kana kusadaira.

MURIWO UNOVAVA UNOKURUDZWA PAMUSORO PEMISTARD SIPICHI YEHemangioblastoma NEKURAPA Bevacizumab.

Sarudza Muchero RED RASPBERRY kana PUMMELO?

Chibereko Chitsvuku Raspberry chine zvakawanda zvinoshanda zvinosanganisa kana bioactives seEllagic Acid, Quercetin, Catechol, Daidzein, Delphinidin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical nzira seMAPK Kuratidzira, Hypoxia, TGFB Kuratidzira uye PI3K-AKT-MTOR Kuratidzira uye vamwe. Red Raspberry inokurudzirwa kuHemangioblastoma kana ichienderera mberi kurapwa kwegomarara iri Bevacizumab. Izvi zvinodaro nekuti Red Raspberry inogadzirisa idzo biochemical nzira dzakataurwa nesainzi kuti dzikurudzire maitiro eBevacizumab.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuchero Pummelo ndeye Quercetin, Catechol, Daidzein, Delphinidin, Isoliquiritigenin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seTGFB Signaling uye PI3K-AKT-MTOR Signaling nevamwe. Pummelo haikurudzirwe kuHemangioblastoma kana ichiramba ichirapwa cancer iri Bevacizumab nekuti inogadzirisa idzo biochemical nzira dzinoita kuti kurapwa kwegomarara risarambe kana kusadaira.

MUCHERO RED RASPBERRY INOKURUDZWA PAMUSORO PEPUMMELO YEHemangioblastoma NEKURAPA Bevacizumab.

Sarudza Nut COMMON WALNUT kana MACADAMIA NUT?

Yakajairika Walnut ine akawanda anoshanda zvinhu kana bioactives seEllagic Acid, Quercetin, Catechol, Daidzein, Delphinidin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical nzira seMAPK Kuratidzira, Hypoxia, TGFB Kuratidzira uye PI3K-AKT-MTOR Kuratidzira uye vamwe. Common Walnut inokurudzirwa kuHemangioblastoma kana ichiramba ichirapwa cancer iri Bevacizumab. Izvi zvinodaro nekuti Common Walnut inogadzirisa idzo nzira dzebiochemical dzakataurwa nesainzi kuti dzikurudzire maitiro eBevacizumab.

Zvimwe zvezvinhu zvinoshanda kana bioactives muMacadamia Nut iCatechol, Daidzein, Delphinidin, Isoliquiritigenin, Cinnamaldehyde. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical nzira seMAPK Signaling, TGFB Signaling uye PI3K-AKT-MTOR Signaling nevamwe. Macadamia Nut haikurudzirwe kuHemangioblastoma kana ichiramba ichirapwa kenza iri Bevacizumab nekuti inogadzirisa idzo biochemical nzira dzinoita kuti kurapwa kwegomarara kurambe kana kusadaira.

WALNUT YAKAWANDA INOKUDZWA PAMUSORO PEMACADAMIA NUT YEHemangioblastoma UYE KURAPA Bevacizumab.

Kune Vanhu Vane Genetic Risk yeCancer

Mubvunzo wakabvunzwa nevanhu vane genetic risk yeHemangioblastoma kana nhoroondo yemhuri ndeye "Chii Chandinofanira Kudya Zvakasiyana Kubva Kare?" uye masarudzire avanofanira kuita zvekudya uye zvekuwedzera kuti vatarise njodzi dzechirwere. Sezvo kune njodzi yegomarara hapana chinogoneka maererano nekurapa - sarudzo dzezvekudya uye zvekuwedzera zvinove zvakakosha uye chimwe chezvinhu zvishoma zvingaite zvinogona kuitwa. Zvese zvinodyarwa-zvikafu hazvina kuenzana uye zvichibva pane zvakazivikanwa genetics uye nzira siginecha - sarudzo dzechikafu nekuwedzera dzinofanirwa kuve munhu.

Sarudza Vegetable GIANT BUTTERBUR kana MEXICAN GROUNDCHERRY?

Vegetable Giant Butterbur ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seApigenin, Curcumin, Lycopene, Vitamin C, Catechol. Izvi zvinoshandiswa zvinosanganisa zvinoshandisa nzira dzakasiyana dzebiochemical seMAPK Signaling, Carbohydrate Metabolism, Stem Cell Signaling uye Post Dudziro Modhisheni uye nevamwe. Giant Butterbur inokurudzirwa kune njodzi yeHemangioblastoma kana yakabatana genetic njodzi iri FUS. Izvi zvinodaro nekuti Giant Butterbur inowedzera idzo biochemical nzira dzinopokana nemadhiraivha emasaini ayo.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuriwo Mexican Groundcherry ndeapigenin, Curcumin, Catechol, Protocatechuic Acid, Kaempferol. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seEndoplasmic Reticulum Stress uye Stem Cell Signaling uye vamwe. Mexican Groundcherry haikurudzirwe kana njodzi yeHemangioblastoma kana yakabatana genetic njodzi iri FUS nekuti inowedzera siginecha nzira dzayo.

MURIWO MURUME BUTTERBUR ANOKURUKURWA PAMUSORO PAMEXICAN GROUNDCHERRY YEFUS GENETIC RISK YECANCER.

Sarudza Fruit NANCE kana BREADNUT MUTI MBEU?

Chibereko Nance chine zvakawanda zvinoshanda zvinosanganisa kana bioactives seApigenin, Curcumin, Vitamin C, Catechol, Protocatechuic Acid. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical seMAPK Signaling, Hypoxia uye Carbohydrate Metabolism nevamwe. Nance inokurudzirwa kune njodzi yeHemangioblastoma kana yakabatana genetic njodzi iri FUS. Izvi zvinodaro nekuti Nance inowedzera idzo biochemical nzira dzinopokana nemadhiraivha emasaini ayo.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuchero Breadnut Tree Mbeu ndeye Apigenin, Curcumin, Lycopene, Catechol, Protocatechuic Acid. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seEndoplasmic Reticulum Stress uye Stem Cell Signaling uye vamwe. Breadnut Tree Mbeu haikurudzirwe kana njodzi yeHemangioblastoma kana yakabatana genetic njodzi iri FUS nekuti inowedzera siginecha nzira dzayo.

FRUIT NANCE INOKURUDZWA PAMUSORO PAMUSORO MBEU YEMUTI WEBREADNUT FOR FUS GENETIC RISK OF CANCER.

Sarudza Nut BUTTERNUT kana ALMOND?

Butternut ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seApigenin, Curcumin, Lycopene, Catechol, Protocatechuic Acid. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical nzira seMAPK Kusaina, Endoplasmic Reticulum Stress, Stem Cell Signaling uye MYC Signaling nevamwe. Butternut inokurudzirwa kune njodzi yeHemangioblastoma kana yakabatana neiyo genetic njodzi iri FUS. Izvi zvinodaro nekuti Butternut inowedzera idzo nzira dzebiochemical dzinopesana nemadhiraivha ayo.

Zvimwe zvezvinhu zvinoshanda kana bioactives muAlmond ndeye Curcumin, Catechol, Isoliquiritigenin, Phloretin, Melatonin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seEndoplasmic Reticulum Stress uye vamwe. Almond haikurudzirwe kana njodzi yeHemangioblastoma kana yakabatana genetic njodzi iri FUS nekuti inowedzera siginecha nzira dzayo.

BUTTERNUT INOKURUDZWA PAMUSORO PEARMOND YEFUS GENETIC RISK YECANCER.

Mhedziso

Chikafu uye Zvekuwedzera zvakasarudzwa sarudzo dzakakosha kune cancer seHemangioblastoma. Varwere veHemangioblastoma uye vanhu vane genetic-njodzi vanogara vaine mubvunzo uyu: "Ndezvipi zvekudya uye zvinovaka muviri zvinokurudzirwa kwandiri uye izvo zvisiri?" Pane chitendero chakajairika chinova fungidziro isiriyo yekuti zvese zvinodyarwa-zvikafu zvinogona kubatsira kana kwete asi zvisingakuvadze. Zvimwe zvekudya uye zvekuwedzera zvinogona kukanganisa marapirwo egomarara kana kusimudzira mamorekuru enzira yegomarara.

Kune marudzi akasiyana ezviratidzo zvegomarara senge Hemangioblastoma, imwe neimwe iine bundu genetics ine mamwe ma genomic akasiyana pamunhu wega wega. Kuwedzera kurapwa kwegomarara uye chemotherapy ine yakasarudzika nzira yekuita. Chikafu chega chega seBitter Gourd chine akasiyana bioactives muhuwandu hwakasiyana, izvo zvine chekuita neakasiyana uye akasiyana seti yebiochemical nzira. Tsanangudzo yekudya yakasarudzika ndeyakasarudzika chikafu kurudziro yegomarara chiratidzo, marapirwo, genetics, mararamiro uye zvimwe zvinhu. Sarudzo dzehutano hwemunhu hwegomarara dzinoda ruzivo rwegomarara biology, sainzi yechikafu uye kunzwisisa kweakasiyana chemotherapy marapirwo. Chekupedzisira kana paine shanduko yekurapa kana nyowani genomics inoonekwa - iyo inovaka muviri inoda kuongororwazve.

Iyo addon nutrition personalization mhinduro inoita kuti sarudzo ive nyore uye inobvisa zvese zvekufungidzira mukupindura mubvunzo, "Ndezvipi zvekudya zvandinofanira kusarudza kana kusasarudzira Hemangioblastoma?". Iyo addon yakawanda-yekuranga timu inosanganisira varapi vegomarara, masayendisiti ekiriniki, mainjiniya esoftware uye masayendisiti edata.

References

• Msk Impact 2017
• Mutational landscape yekenza yemetastatic yakaratidzwa kubva kune vangangove vanotarisirwa kutevedzana kwevarwere zviuru gumi.
• Daidzein mhedzisiro pahomoni refractory prostate cancer in vitro uye in vivo ichienzaniswa negenistein uye soy inobvisa: kugona kweradiotherapy.
• Melatonin uye vhitamini D3 synergistically pasi-regulate Akt uye MDM2 inotungamira kuTGFβ-1-inotsamira kukura inhibition yekenza yemazamu maseru.
• Lycopene attenuated hepatic tumorigenesis kuburikidza nenzira dzakasiyana zvichienderana necarotenoid cleavage enzyme mumakonzo.
• https://rarediseases.info.nih.gov/diseases/8232/hemangioblastoma
• https://www.healthline.com/health/hemangioblastoma