Zvokudya zveGastrointestinal Stromal Sarcoma!

ziviso

Zvikafu zveGastrointestinal Stromal Sarcoma zvinofanirwa kuve zvakasarudzika kune wega wega uye zvakare zvinofanirwa kuchinjika kana kenza kurapwa kana bundu genetic shanduko. Iyo yemunhu uye kugadzirisa kunofanirwa kufunga nezvese zvinoshanda zvinosanganiswa kana bioactives zviri muzvokudya zvakasiyana zvine chekuita negomarara biology, genetics, marapirwo, mararamiro uye zvido zvekudya. Saka nepo chikafu chiri chimwe chezvisarudzo zvakakosha zvemurwere wegomarara uye munhu ari panjodzi yegomarara - kusarudza chikafu chekudya harisi basa riri nyore.

ZveGastrointestinal Stromal Sarcoma zvine basa here kuti miriwo, michero, nzungu, mhodzi anodya chii?

Mubvunzo wakajairika wekudya unobvunzwa nevarwere vegomarara uye vanhu vari pa-genetic njodzi yegomarara ndeye - kumakonza akaita seGastrointestinal Stromal Sarcoma zvine basa here kuti ndechipi chikafu chandinodya uye chandisingade? Kana kuti ndikatevera kudya-kwekudyara kunokwana gomarara seGastrointestinal Stromal Sarcoma?

Semuenzaniso zvine basa here kana muriwo Bitter Gourd ukadyiwa zvakanyanya uchienzaniswa neKohlrabi? Zvinoita mutsauko here kana muchero Pummelo uchifarirwa pane Pomegranate? Zvakare kana sarudzo dzakafanana dzakaitirwa nzungu/mhodzi dzakaita seButternut pamusoro peChestnut uye dzemapulses seAdzuki Bean pamusoro peLima Bean. Uye kana zvandinodya zvine basa - zvino munhu angaziva sei zvikafu zvinokurudzirwa kuGastrointestinal Stromal Sarcoma uye ndiyo mhinduro imwechete kune wese ane chirwere chakafanana kana genetic njodzi?

Ehe! Zvokudya zvaunodya zvine chekuita neGastrointestinal Stromal Sarcoma!

Mazano echikafu anogona kunge asina kufanana kune wese munhu uye anogona kuve akasiyana kunyangwe kune imwechete kuongororwa uye genetic njodzi.

Zvokudya zvose (miriwo, michero, nzungu, mhodzi, pulses, mafuta nezvimwewo) uye zvokudya zvinovaka muviri zvinoumbwa nezvinodarika imwe inoshanda mamolecular ingredient kana bio-actives muzvikamu zvakasiyana uye uwandu. Chinhu chimwe nechimwe chinoshanda chine nzira yakasarudzika yekuita - iyo inogona kuve activation kana inhibition yeakasiyana biochemical nzira. Zvikafu zvakangotaurwa uye zvekuwedzera izvo zvinokurudzirwa ndezviya zvisingakonzere kuwedzera kwemamorekuru anotyaira cancer asi anodzideredza. Zvikasadaro izvo zvikafu hazvifanirwe kukurudzirwa. Chikafu chine akawanda anoshanda zvinongedzo - saka kana uchiongorora chikafu uye zvekuwedzera iwe unofanirwa kufunga nezve mabatiro ezvese zvinoshanda zvinongedzo zvakapetwa kwete zvega.

Somuenzaniso Pummelo ine zvinhu zvinoshanda Quercetin, Curcumin, Formononetin, Lupeol, Daidzein. Uye Pomegranate ine inoshanda zvinoshandiswa Ellagic Acid, Quercetin, Curcumin, Formononetin, Lupeol uye pamwe nevamwe.

Chikanganiso chinowanzoitwa pakusarudza nekusarudza chikafu chekudya cheGastrointestinal Stromal Sarcoma - kuongorora chete zvakasarudzwa zvinoshandiswa zviri muzvokudya uye kufuratira zvimwe. Nekuti zvakasiyana-siyana zvinoshanda zviri muzvokudya zvinogona kuva nemhedzisiro inopikisa kune vatyairi vegomarara - haugone kutora cherry inoshanda mukudya uye ma supplements ekuita sarudzo yehutano hweGastrointestinal Stromal Sarcoma.

HONGU – ZVOKUSARUDZA ZVOKUDYA ZVINOKOSHA NEGONSA. ZVISARUDZO ZVOKUDYA ZVINOFANIRA KUFUNGA ZVINHU ZVINHU ZVINHU ZVINOSHANDA PACHIDYA.

Hunyanzvi hunodiwa paKudya Kwekudya Kwemunhu kune Gastrointestinal Stromal Sarcoma?

Kudya kwakasarudzika kwegomarara seGastrointestinal Stromal Sarcoma ine zvinokurudzirwa zvekudya / zvinowedzera; zvisingakurudzirwe chikafu / ma supplements ane semuenzaniso mabikirwo anotungamira kushandiswa kwezvikafu zvinokurudzirwa. Muenzaniso wekudya kwakasiyana-siyana unogona kuonekwa pane izvi batanidzo.

Kufunga kuti ndezvipi zvekudya zvinokurudzirwa kana kwete zvakaomesesa, zvinoda hunyanzvi muGastrointestinal Stromal Sarcoma biology, sainzi yechikafu, genetics, biochemistry pamwe nekunzwisisa kwakanaka kwemashandiro anoita marapirwo egomarara uye kusagadzikana kwakabatana uko kurapwa kwaigona kumira kushanda.

ZVINONYANYA ZVINONYANYA ZVINODIWA KUTI ZVINOVAKA ZVINOVAKA MUNHU ZVINHU ZVINHU ZVINOITA: CANCER BIOLOGY, FOOD SCIENCE, KURAPA MAKANZA UYE GENETICS.

Hunhu hwegomarara seGastrointestinal Stromal Sarcoma

Magomarara ese akaita seGastrointestinal Stromal Sarcoma anogona kuratidzirwa neyakasiyana seti yebiochemical nzira - iyo siginecha nzira dzeGastrointestinal Stromal Sarcoma. Nzira dzeBiochemical dzakadai seSero Cycle, MAPK Signaling, PI3K-AKT-MTOR Signaling, Growth Factor Signaling chikamu chetsanangudzo yeGastrointestinal Stromal Sarcoma. Kenza yemunhu wega genetics inogona kuve yakasiyana uye nekudaro siginicha yavo yegomarara inogona kuve yakasarudzika.

Kurapa kunoshanda kweGastrointestinal Stromal Sarcoma kunoda kuziva nezve siginecha yebiochemical nzira kune wese murwere wegomarara uye munhu ari panjodzi yemajini. Saka marapirwo akasiyana ane maitiro akasiyana ezviito anoshanda kune varwere vakasiyana. Saizvozvo uye nekuda kwezvikonzero zvakafanana zvekudya uye zvekuwedzera zvinoda kuitirwa munhu wega wega. Saka zvimwe zvekudya uye zvekuwedzera zvinokurudzirwa kune Gastrointestinal Stromal Sarcoma kana uchitora cancer kurapwa Octreotide, uye zvimwe zvekudya uye zvekuwedzera hazvikurudzirwe.

Sources like cBioPortal uye vamwe vazhinji vanopa mumiriri wehuwandu hwevarwere data risingazivikanwe kubva kukiriniki miedzo yezvese zviratidzo zvegomarara. Iyi dhata ine yekiriniki yekuongorora yeruzivo senge sampuli saizi / nhamba yevarwere, mapoka ezera, murume kana mukadzi, dzinza, marapirwo, bundu saiti uye chero genetic mutations.

KIT, TSC1, SETD2, MAX uye PDGFRA ndiwo epamusoro akaverengerwa majini eGastrointestinal Stromal Sarcoma. KIT inoshumwa mu5.2% yevanomiririra varwere mukati meyese miedzo yekiriniki. Uye TSC1 inoshumwa mu1.1%. Kubatanidzwa kwehuwandu hwehuwandu hwemurwere data inovhara makore kubva pa16 kusvika ku90. 55.2 % yedata revarwere vanoonekwa sevarume. Iyo Gastrointestinal Stromal Sarcoma biology pamwe neyakashumwa genetics pamwe chete inotsanangura huwandu hwehuwandu hunomiririrwa nemasaini ebiochemical nzira dzegomarara iri. Kana iyo yega cancer tumor genetics kana majini anokonzera njodzi achizivikanwawo saka izvo zvinofanirwa kushandiswawo kune hutano hwemunhu.

ZVAKASARUDZA KUDYA ZVINODYA ZVINOFANIRA KUFANIRA NEMUNHU WEMUNHU WEMUNHU WEMUNHU WEGONSI.

Chikafu uye Zvekuwedzera zveGastrointestinal Stromal Sarcoma

Kune Varwere veCancer

Varwere vegomarara vari pakurapa kana pakuchengeta palliative vanofanira kuita sarudzo pazvekudya uye zvekuwedzera - zvemacalorie anodiwa ekudya, kubata chero mhedzisiro yekurapa uyezve nekugadzirisa kenza. Zvese zvinodyarwa-zvikafu hazvina kuenzana uye kusarudza uye kuisa pamberi pezvikafu zvakagadzirirwa munhu uye zvakagadzirirwa kuenderera mberi kurapwa kwegomarara kwakakosha uye kwakaoma. Heano mimwe mienzaniso inopa nhungamiro yekuita sarudzo dzekudya.

Sarudza Vegetable BITTER GOURD kana KOHLRABI?

Vegetable Bitter Gourd ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seCurcumin, Formononetin, Lupeol, Daidzein, Isoliquiritigenin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical seMAPK Kusaina, JAK-STAT Signaling, Angiogenesis uye PI3K-AKT-MTOR Kuratidzira uye vamwe. Bitter Gourd inokurudzirwa kuGastrointestinal Stromal Sarcoma apo kurapwa kwegomarara kuri kuramba kuchiitwa Octreotide. Izvi zvinodaro nekuti Bitter Gourd inogadziridza idzo nzira dzebiochemical dzakataurwa nesainzi kuti dzikurudzire kuita kweOctreotide.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuriwo Kohlrabi ndeye Quercetin, Curcumin, Formononetin, Lupeol, Daidzein. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical seMAPK Kusaina, WNT Beta Catenin Signaling uye PI3K-AKT-MTOR Kuratidzira uye vamwe. Kohlrabi haikurudzirwe kune Gastrointestinal Stromal Sarcoma kana ichienderera mberi kurapwa kwegomarara iri Octreotide nekuti inogadzirisa iwo biochemical nzira dzinoita kuti kurapwa kwegomarara kumire kana kusadaira.

MURIWO UNORUVA UNORUDZIRWA PAMUSORO PAKOHLRABI YEGastrointestinal Stromal Sarcoma UYE KURAPA Octreotide.

Sarudza Muchero POMEGRANATE kana PUMMELO?

Muchero Damba rine zvakawanda zvinoshanda zvinosanganisa kana bioactives seEllagic Acid, Quercetin, Curcumin, Formononetin, Lupeol. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical senge MAPK Signaling, Angiogenesis, Growth Factor Signaling uye PI3K-AKT-MTOR Signaling nevamwe. Pomegranate inokurudzirwa kuGastrointestinal Stromal Sarcoma apo kurapwa kwegomarara kuri kuramba kuchiitwa Octreotide. Izvi zvinodaro nekuti Damba rinogadzirisa nzira dziya dzebiochemical dzakataurwa nesainzi kuti dzikurudzire kuita kweOctreotide.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuchero Pummelo ndeye Quercetin, Curcumin, Formononetin, Lupeol, Daidzein. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seWNT Beta Catenin Signaling uye PI3K-AKT-MTOR Signaling nevamwe. Pummelo haikurudzirwe kuGastrointestinal Stromal Sarcoma kana ichiramba ichirapwa kenza iri Octreotide nekuti inogadzirisa idzo biochemical nzira dzinoita kuti kurapwa kwegomarara risarambe kana kusadaira.

MUCHERO POMEGRANATE INOKURUDZWA PAMUSORO PEPUMMELO YEGastrointestinal Stromal Sarcoma UYE KURAPA Octreotide.

Sarudza Nut BUTTERNUT kana CHESTNUT?

Butternut ine zvinhu zvakawanda zvinoshanda kana bioactives seCurcumin, Formononetin, Lupeol, Daidzein, Isoliquiritigenin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical seMAPK Kusaina, JAK-STAT Signaling, Angiogenesis uye PI3K-AKT-MTOR Kuratidzira uye vamwe. Butternut inokurudzirwa kuGastrointestinal Stromal Sarcoma apo chirwere chegomarara chiri kuramba chiri Octreotide. Izvi zvinodaro nekuti Butternut inogadzirisa idzo nzira dzebiochemical dzakataurwa nesainzi kuti dzikurudzire kuita kweOctreotide.

Zvimwe zvezvinhu zvinoshanda kana bioactives muChestnut ndeye Ellagic Acid, Curcumin, Formononetin, Lupeol, Daidzein. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seWNT Beta Catenin Signaling uye PI3K-AKT-MTOR Signaling nevamwe. Chestnut haikurudzirwe kuGastrointestinal Stromal Sarcoma kana ichiramba ichirapwa cancer iri Octreotide nekuti inogadzirisa nzira dziya dzebiochemical dzinoita kuti kurapwa kwegomarara risarambe kana kusadaira.

BUTTERNUT INOKURUMBIRWA PAMUSORO PACHESTNUT YEGastrointestinal Stromal Sarcoma UYE KURAPA Octreotide.

Kune Vanhu Vane Genetic Risk yeCancer

Mubvunzo wakabvunzwa nevanhu vane genetic risk yeGastrointestinal Stromal Sarcoma kana nhoroondo yemhuri ndeye "Chii Chandinofanira Kudya Zvakasiyana Kubva Kare?" uye masarudzire avanofanira kuita zvekudya uye zvekuwedzera kuti vatarise njodzi dzechirwere. Sezvo kune njodzi yegomarara hapana chinogoneka maererano nekurapa - sarudzo dzezvekudya uye zvekuwedzera zvinove zvakakosha uye chimwe chezvinhu zvishoma zvingaite zvinogona kuitwa. Zvese zvinodyarwa-zvikafu hazvina kuenzana uye zvichibva pane zvakazivikanwa genetics uye nzira siginecha - sarudzo dzechikafu nekuwedzera dzinofanirwa kuve munhu.

Sarudza Vegetable CAULIFLOWER kana RED BELL PEPPER?

Vegetable Cauliflower ine akawanda anoshanda zvinhu kana bioactives akadai Curcumin, Lupeol, Isoliquiritigenin, Daidzein, Phloretin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical seMAPK Signaling, RAS-RAF Signaling, Angiogenesis uye PI3K-AKT-MTOR Signaling nevamwe. Koliflower inokurudzirwa kune njodzi yeGastrointestinal Stromal Sarcoma kana njodzi yemajini yakabatana iri KIT. Izvi zvinodaro nekuti Cauliflower inowedzera idzo nzira dzebiochemical dzinopokana nemadhiraivha ayo anosaina.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuriwo Red Bell Pepper ndeye Quercetin, Curcumin, Lupeol, Luteolin, Isoliquiritigenin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical seMAPK Signaling uye Stem Cell Signaling nevamwe. Red Bell Pepper haikurudzirwe kana njodzi yeGastrointestinal Stromal Sarcoma kana yakabatana nejeneki njodzi iri KIT nekuti inowedzera siginecha nzira dzayo.

VEGETABLE CAULIFLOWER INAKURUDZIRWA PAMUSORO PAMUSORO RED BELL PEPPER YEKIT GENETIC RISK YECANCER.

Sarudza Muchero BILBERRY kana SWEET ORANGE?

Chibereko Bilberry ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seApigenin, Quercetin, Curcumin, Lupeol, Luteolin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical senge MAPK Kusaina, MYC Signaling, Stem Cell Signaling uye PI3K-AKT-MTOR Signaling nevamwe. Bilberry inokurudzirwa kune njodzi yeGastrointestinal Stromal Sarcoma kana njodzi yemajini yakabatana iri KIT. Izvi zvinodaro nekuti Bilberry inowedzera idzo biochemical nzira dzinopokana nemadhiraivha emasaini ayo.

Zvimwe zvezvishandiso zvinoshandiswa kana bioactives mumuchero Inotapira Orange ndeye D-limonene, Curcumin, Lupeol, Vitamin D3, Luteolin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical seSero Cycle, Stem Cell Signaling uye PI3K-AKT-MTOR Signaling nevamwe. Sweet Orange haikurudzirwe kana njodzi yeGastrointestinal Stromal Sarcoma kana yakabatana genetic njodzi iri KIT nekuti inowedzera siginecha nzira dzayo.

FRUIT BILBERRY INOKURUKURWA PAMUSORO PAMUSORO ZVINOTADZA ORANGE YEKIT GENETIC RISK YECANCER.

Sarudza Nut COMMON HAZELNUT kana EUROPEAN CHESTNUT?

Common Hazelnut ine akawanda anoshanda zvinhu kana bioactives seQuercetin, Curcumin, Lupeol, Isoliquiritigenin, Daidzein. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical senge MAPK Kusaina, MYC Signaling, Stem Cell Signaling uye PI3K-AKT-MTOR Signaling nevamwe. Common Hazelnut inokurudzirwa kune njodzi yeGastrointestinal Stromal Sarcoma kana njodzi yemajini yakabatana iri KIT. Izvi zvinodaro nekuti Common Hazelnut inowedzera idzo biochemical nzira dzinopokana nemadhiraivha emasaini ayo.

Zvimwe zvezvinhu zvinoshanda kana bioactives muEuropean Chestnut ndeye Apigenin, Quercetin, Curcumin, Ellagic Acid, Lupeol. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seStem Cell Signaling uye vamwe. European Chestnut haikurudzirwe kana njodzi yeGastrointestinal Stromal Sarcoma kana yakabatana nejeneki njodzi iri KIT nekuti inowedzera siginicha nzira dzayo.

COMMON HAZELNUT INOKURUKURWA PAMUSORO PEEUROPA CHESTNUT YEKIT GENETIC RISK YECANCER.

Mhedziso

Chikafu uye Zvekuwedzera zvakasarudzwa sarudzo dzakakosha dzegomarara seGastrointestinal Stromal Sarcoma. Gastrointestinal Stromal Sarcoma varwere uye vanhu vane genetic-njodzi vanogara vaine mubvunzo uyu: "Ndezvipi zvekudya uye zvinovaka muviri zvinokurudzirwa ini uye izvo zvisiri?" Pane chitendero chakajairika chinova fungidziro isiriyo yekuti zvese zvinodyarwa-zvikafu zvinogona kubatsira kana kwete asi zvisingakuvadze. Zvimwe zvekudya uye zvekuwedzera zvinogona kukanganisa marapirwo egomarara kana kusimudzira mamorekuru enzira yegomarara.

Kune marudzi akasiyana ezviratidzo zvegomarara seGastrointestinal Stromal Sarcoma, imwe neimwe iine tumor genetics ine mamwe ma genomic akasiyana pamunhu wega wega. Kuwedzera kurapwa kwegomarara uye chemotherapy ine yakasarudzika nzira yekuita. Chikafu chega chega seBitter Gourd chine akasiyana bioactives muhuwandu hwakasiyana, izvo zvine chekuita neakasiyana uye akasiyana seti yebiochemical nzira. Tsanangudzo yekudya yakasarudzika ndeyakasarudzika chikafu kurudziro yegomarara chiratidzo, marapirwo, genetics, mararamiro uye zvimwe zvinhu. Sarudzo dzehutano hwemunhu hwegomarara dzinoda ruzivo rwegomarara biology, sainzi yechikafu uye kunzwisisa kweakasiyana chemotherapy marapirwo. Chekupedzisira kana paine shanduko yekurapa kana nyowani genomics inoonekwa - iyo inovaka muviri inoda kuongororwazve.

Iyo addon nutrition personalization solution inoita kuti sarudzo ive nyore uye inobvisa zvese zvekufungidzira mukupindura mubvunzo, "Ndezvipi zvekudya zvandinofanira kusarudza kana kusasarudzira Gastrointestinal Stromal Sarcoma?". Iyo addon yakawanda-yekuranga timu inosanganisira varapi vegomarara, masayendisiti ekiriniki, mainjiniya esoftware uye masayendisiti edata.

References

• Msk Impact 2017
• Cancer therapy inoumba kusimba kwenzvimbo ye clonal hematopoiesis.
• Kudzivirira mhedzisiro yebutyric acid, nicotinamide, calcium glucarate yoga kana musanganiswa panguva ye7, 12-dimethylbenz (a) anthracene induced mouse skin tumorigenesis kuburikidza nemodulation yeK-Ras-PI3K-AKTpathway uye yakabatana micro RNAs.
• Betulinic acid inhibisa kenza yeprostate kukura kuburikidza nekudzivirirwa kweiyo chaiyo protein transcription factor.
• Gallic acid, a phenolic compound, inoshandisa anti-angiogenic migumisiro kuburikidza nePTEN/AKT/HIF-1α/VEGF nzira yechiratidzo mumasero ekenza ye ovarian.
• Kukura kwekukurudzira kwemasero emunhu pulmonary adenocarcinoma uye madiki epithelial masero emhepo ne beta-carotene kuburikidza ne activation ye cAMP, PKA, CREB uye ERK1/2.
• Mhedzisiro uye kukosha kweformononetin pamatanho ekutaura eHIF-1α uye VEGF mune mbeva yecervical cancer tissue.
• Negative regulation ye signal transducer uye activator ye transcription-3 signing cascade ne lupeol inhibits kukura uye induces apoptosis muhepatocellular carcinoma masero.
• Chlorogenic acid inhibits kuwanda uye induces apoptosis muA498 masero ekenza yeitsvo yemunhu kuburikidza nekusaita PI3K/Akt/mTOR nzira yekusaina.
• Brassinin inhibits STAT3 yekusaina nzira kuburikidza nemodulation yePIAS-3 uye SOCS-3 kutaura uye inosimbisa kenza yemapapu yemunhu xenograft mu nude mice kuenda paclitaxel.
• Kukonzeresa kwenguva pfupi receptor inogona vanilloid mhando 1 (TRPV1) ne capsaicin induces Fas/CD95-mediated apoptosis yemasero ekenza yeurothelial nenzira inoenderana neATM.