Zvokudya zveChondroblastic Osteosarcoma!

ziviso

Zvikafu zveChondroblastic Osteosarcoma zvinofanirwa kuve zvakasarudzika kune wega wega uye zvakare zvinofanirwa kuchinjika kana kenza kurapwa kana bundu genetic shanduko. Iyo yemunhu uye kugadzirisa kunofanirwa kufunga nezvese zvinoshanda zvinosanganiswa kana bioactives zviri muzvokudya zvakasiyana zvine chekuita negomarara biology, genetics, marapirwo, mararamiro uye zvido zvekudya. Saka nepo chikafu chiri chimwe chezvisarudzo zvakakosha zvemurwere wegomarara uye munhu ari panjodzi yegomarara - kusarudza chikafu chekudya harisi basa riri nyore.

Chondroblastic osteosarcoma, subtype yegomarara reosteosarcoma inoratidzwa nekugadzirwa kwecartilaginous matrix, inopa matambudziko akasiyana mukuongororwa uye kurapwa. Iyo pathology rondedzero uye histology ye chondroblastic osteosarcoma inoratidza maitiro ayo akasiyana, anosanganisira chondroid uye osteoid zvinhu, izvo zvakakosha pakuisiyanisa kubva kuchondrosarcoma. Radiology, kunyanya MRI uye CT scans, inoita basa rakakosha mukuongororwa kwebundu, ichipa mifananidzo yakadzama yehukuru hwaro uye chiyero. Gomarara iri, rakafukidzwa pasi pechikamu cheICD-10, rinogona kubata vanhu nemhuka, nenyaya dzinocherechedzwa mumbwa. Zviratidzo zvinowanzo sanganisira kurwadziwa uye kuzvimba panzvimbo yebundu, izvo zvinogona kuitika mumapfupa akasiyana siyana, kusanganisira shaya uye maxilla. Mwero wekupona uye fungidziro yechondroblastic osteosarcoma inosiyana, zvichienderana nezvinhu zvakaita senzvimbo yebundu racho, saizi, uye mhinduro pakurapwa. Kurapa kunowanzo sanganisira musanganiswa wekuvhiya uye chemotherapy, ine chinangwa chekubvisa bundu uye kuderedza njodzi yemetastasis. Kunzwisisa zvinokonzeresa chondroblastic osteosarcoma, kunyangwe ichiri pasi pekutsvagirwa, kwakakosha pakugadzira nzira dzekudzivirira. Kutarisira kwegomarara iri rinotyisa kunoda nzira yemhando dzakasiyana siyana, yakatarisana nekuvhiya kubviswa kwebundu uye kurapwa kwehurongwa kuvandudza mikana yemhedzisiro yakanaka kune varwere vanobatwa nemamiriro ezvinhu akaomarara.

Kune Chondroblastic Osteosarcoma zvine basa kuti miriwo, michero, nzungu, mhodzi anodya chii?

Mubvunzo wakajairika wekudya unobvunzwa nevarwere vegomarara uye vanhu vari pa-genetic njodzi yegomarara ndeye - yegomarara seChondroblastic Osteosarcoma zvine basa kuti ndechipi chikafu chandinodya uye chandisingade? Kana kuti kana ndikatevera kudya-kwekudyara kunokwana kenza seChondroblastic Osteosarcoma?

Semuyenzaniso zvine basa here kana muriwo Wild Leek uchidyiwa zvakanyanya uchienzaniswa neRomaine Lettuce? Zvinoita mutsauko here kana muchero Pummelo uchifarirwa pane Red Raspberry? Zvakare kana sarudzo dzakafanana dzakaitirwa nzungu/mhodzi dzakaita seCommon Hazelnut pamusoro peEuropean Chestnut uye yemapuruzi akaita seHyacinth Bean pamusoro pePigeon Pea. Uye kana izvo zvandinodya zvine basa - zvino munhu angaziva sei zvikafu zvinokurudzirwa Chondroblastic Osteosarcoma uye ndiyo mhinduro imwechete kune wese ane chirwere chakafanana kana genetic njodzi?

Ehe! Zvokudya zvaunodya zvine chekuita neChondroblastic Osteosarcoma!

Mazano echikafu anogona kunge asina kufanana kune wese munhu uye anogona kuve akasiyana kunyangwe kune imwechete kuongororwa uye genetic njodzi.

Zvokudya zvose (miriwo, michero, nzungu, mhodzi, pulses, mafuta nezvimwewo) uye zvokudya zvinovaka muviri zvinoumbwa nezvinodarika imwe inoshanda mamolecular ingredient kana bio-actives muzvikamu zvakasiyana uye uwandu. Chinhu chimwe nechimwe chinoshanda chine nzira yakasarudzika yekuita - iyo inogona kuve activation kana inhibition yeakasiyana biochemical nzira. Zvikafu zvakangotaurwa uye zvekuwedzera izvo zvinokurudzirwa ndezviya zvisingakonzere kuwedzera kwemamorekuru anotyaira cancer asi anodzideredza. Zvikasadaro izvo zvikafu hazvifanirwe kukurudzirwa. Chikafu chine akawanda anoshanda zvinongedzo - saka kana uchiongorora chikafu uye zvekuwedzera iwe unofanirwa kufunga nezve mabatiro ezvese zvinoshanda zvinongedzo zvakapetwa kwete zvega.

Semuyenzaniso Pummelo ine zvinoshanda zvinosanganisa Curcumin, Quercetin, Caffeine, Lupeol, Formononetin. Uye Red Raspberry ine inoshanda zvinoshandiswa Ellagic Acid, Curcumin, Quercetin, Lupeol, Formononetin uye pamwe nevamwe.

Chikanganiso chakajairika pakusarudza nekusarudza chikafu chekudya cheChondroblastic Osteosarcoma - kuongorora chete zvakasarudzwa zvinoshandiswa zviri muzvokudya uye kufuratira zvimwe. Nekuti zvakasiyana-siyana zvinoshanda zviri mukudya zvinogona kuve nemhedzisiro inopikisa kune vatyairi vegomarara - haugone kutora cherry inoshanda mukudya uye ma supplements ekuita sarudzo yehutano hweChondroblastic Osteosarcoma.

HONGU – ZVOKUSARUDZA ZVOKUDYA ZVINOKOSHA NEGONSA. ZVISARUDZO ZVOKUDYA ZVINOFANIRA KUFUNGA ZVINHU ZVINHU ZVINHU ZVINOSHANDA PACHIDYA.

Unyanzvi hunodiwa paKudya Kwekudya Kwemunhu kune Chondroblastic Osteosarcoma?

Kudya kwakasarudzika kwekenza seChondroblastic Osteosarcoma ine zvinokurudzirwa zvekudya / zvinowedzera; zvisingakurudzirwe chikafu / ma supplements ane semuenzaniso mabikirwo anotungamira kushandiswa kwezvikafu zvinokurudzirwa. Muenzaniso wekudya kwakasiyana-siyana unogona kuonekwa pane izvi batanidzo.

Kufunga kuti ndezvipi zvekudya zvinokurudzirwa kana kwete zvakaomesesa, zvinoda hunyanzvi muChondroblastic Osteosarcoma biology, sainzi yechikafu, genetics, biochemistry pamwe nekunzwisisa kwakanaka kwemashandiro anoita marapirwo egomarara uye kusagadzikana kwakabatana uko kurapwa kwaigona kumira kushanda.

ZVINONYANYA ZVINONYANYA ZVINODIWA KUTI ZVINOVAKA ZVINOVAKA MUNHU ZVINHU ZVINHU ZVINOITA: CANCER BIOLOGY, FOOD SCIENCE, KURAPA MAKANZA UYE GENETICS.

Hunhu hwegomarara seChondroblastic Osteosarcoma

Ese magomarara seChondroblastic Osteosarcoma anogona kuratidzirwa neyakasiyana seti ye biochemical nzira - siginecha nzira dzeChondroblastic Osteosarcoma. Biochemical pathways seSero Cycle, Angiogenesis, PI3K-AKT-MTOR Kuratidzira, Oncogenic Cancer Epigenetics chikamu chetsanangudzo yeSiginecha yeChondroblastic Osteosarcoma. Kenza yemunhu wega genetics inogona kuve yakasiyana uye nekudaro siginicha yavo yegomarara inogona kuve yakasarudzika.

Iwo marapirwo anoshanda eChondroblastic Osteosarcoma anofanirwa kuziva iyo inosanganisirwa siginecha biochemical nzira kune yega yega murwere wegomarara uye munhu ari panjodzi yemajini. Saka marapirwo akasiyana ane maitiro akasiyana ezviito anoshanda kune varwere vakasiyana. Saizvozvo uye nekuda kwezvikonzero zvakafanana zvekudya uye zvekuwedzera zvinoda kuitirwa munhu wega wega. Saka zvimwe zvekudya uye zvekuwedzera zvinokurudzirwa Chondroblastic Osteosarcoma kana uchitora cancer kurapwa Radiation, uye zvimwe zvekudya uye zvekuwedzera hazvikurudzirwe.

Sources like cBioPortal uye vamwe vazhinji vanopa mumiriri wehuwandu hwevarwere data risingazivikanwe kubva kukiriniki miedzo yezvese zviratidzo zvegomarara. Iyi dhata ine yekiriniki yekuongorora yeruzivo senge sampuli saizi / nhamba yevarwere, mapoka ezera, murume kana mukadzi, dzinza, marapirwo, bundu saiti uye chero genetic mutations.

TERT, IDH1, IDH2, BCOR uye ERBB3 ndiwo mazita emhando yepamusoro anonzi Chondroblastic Osteosarcoma. TERT inoshumwa mu29.4% yevanomiririra varwere mukati meyese miedzo yekiriniki. Uye IDH1 inoshumwa mu17.6%. Iyo yakasanganiswa yehuwandu hwevarwere data inovhara mazera kubva kusvika . 57.7% yedata revarwere vanoonekwa sevarume. Iyo Chondroblastic Osteosarcoma biology pamwe neyakashumwa genetics pamwe chete inotsanangura huwandu hwehuwandu hunomiririrwa siginecha biochemical nzira dzegomarara iri. Kana iyo yega cancer tumor genetics kana majini anokonzera njodzi achizivikanwawo saka izvo zvinofanirwa kushandiswawo kune hutano hwemunhu.

ZVAKASARUDZA KUDYA ZVINODYA ZVINOFANIRA KUFANIRA NEMUNHU WEMUNHU WEMUNHU WEMUNHU WEGONSI.

Chikafu uye Zvekuwedzera zveChondroblastic Osteosarcoma

Kune Varwere veCancer

Varwere vegomarara vari pakurapa kana pakuchengeta palliative vanofanira kuita sarudzo pazvekudya uye zvekuwedzera - zvemacalorie anodiwa ekudya, kubata chero mhedzisiro yekurapa uyezve nekugadzirisa kenza. Zvese zvinodyarwa-zvikafu hazvina kuenzana uye kusarudza uye kuisa pamberi pezvikafu zvakagadzirirwa munhu uye zvakagadzirirwa kuenderera mberi kurapwa kwegomarara kwakakosha uye kwakaoma. Heano mimwe mienzaniso inopa nhungamiro yekuita sarudzo dzekudya.

Sarudza Vegetable WILD LEEK kana ROMAINE LETTUCE?

Vegetable Wild Leek ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seCurcumin, Lupeol, Formononetin, Phloretin, Apigenin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical senge Oxidative Stress, Cell Cycle, Epithelial kune Mesenchymal Transition uye TGFB Signaling nevamwe. Wild Leek inokurudzirwa kuChondroblastic Osteosarcoma kana ichienderera mberi kurapwa kwegomarara iri Radiation. Izvi zvinodaro nekuti Wild Leek inogadzirisa idzo nzira dzebiochemical dzakataurwa nesainzi kuti dzikurudzire maitiro eRadiation.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuriwo Romaine Lettuce ndeye Curcumin, Lupeol, Phloretin, Formononetin, Apigenin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical senge Oxidative Stress, TGFB Signaling uye DNA Kugadzirisa uye vamwe. Romaine Lettuce haikurudzirwe kune Chondroblastic Osteosarcoma kana ichienderera mberi kurapwa kwegomarara iri Radiation nekuti inogadzirisa idzo biochemical nzira dzinoita kuti kurapwa kwegomarara risarambe kana kusadaira.

VEGETABLE WILD LEEK INOKURUDZWA PAMUSORO PEROMINE LETTUCE YEChondroblastic Osteosarcoma UYE KURAPA Radiation.

Sarudza Muchero RED RASPBERRY kana PUMMELO?

Chibereko Chitsvuku Raspberry chine zvakawanda zvinoshanda zvinosanganisa kana bioactives seEllagic Acid, Curcumin, Quercetin, Lupeol, Formononetin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana-siyana dzebiochemical seOxidative Stress, Epithelial kune Mesenchymal Transition, JAK-STAT Signaling uye PI3K-AKT-MTOR Signaling nevamwe. Red Raspberry inokurudzirwa kuChondroblastic Osteosarcoma apo inoenderera mberi kurapwa kwegomarara iri Radiation. Izvi zvinodaro nekuti Red Raspberry inogadzirisa idzo biochemical nzira dzakataurwa nesainzi kuti dzikurudzire mhedzisiro yeRadiation.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuchero Pummelo ndeye Curcumin, Quercetin, Caffeine, Lupeol, Formononetin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical senge Oxidative Stress nevamwe. Pummelo haikurudzirwe kuChondroblastic Osteosarcoma kana ichienderera mberi kurapwa kwegomarara iri Radiation nekuti inogadzirisa idzo biochemical nzira dzinoita kuti kurapwa kwegomarara rirambe kana kusadaira.

MUCHERO RED RASPBERRY INOKURUDZWA PAMUSORO PAMUSORO PAMUSORO PECHOndroblastic Osteosarcoma UYE KURAPA Radiation.

Sarudza Nut COMMON HAZELNUT kana EUROPEAN CHESTNUT?

Common Hazelnut ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seCurcumin, Quercetin, Caffeine, Lupeol, Formononetin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seAngiogenesis, Cell Cycle, JAK-STAT Signaling uye Epithelial kune Mesenchymal Transition uye vamwe. Common Hazelnut inokurudzirwa kuChondroblastic Osteosarcoma kana ichiramba ichirapwa cancer iri Radiation. Izvi zvinodaro nekuti Common Hazelnut inogadzirisa idzo nzira dzebiochemical dzakataurwa nesainzi kuti dzikurudzire maitiro eRadiation.

Zvimwe zvezvinhu zvinoshanda kana bioactives muEuropean Chestnut ndeyeEllagic Acid, Curcumin, Quercetin, Lupeol, Formononetin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seOxidative Stress uye TGFB Signaling nevamwe. European Chestnut haikurudzirwe kuChondroblastic Osteosarcoma kana ichiramba ichirapwa cancer iri Radiation nekuti inogadzirisa idzo biochemical nzira dzinoita kuti kurapwa kwegomarara risarambe kana kusadaira.

COMMON HAZELNUT INOKURUDZWA PAMUSORO PEEUROPA CHESTNUT YEChondroblastic Osteosarcoma UYE KURAPA Radiation.

Kune Vanhu Vane Genetic Risk yeCancer

Mubvunzo wakabvunzwa nevanhu vane genetic risk yeChondroblastic Osteosarcoma kana nhoroondo yemhuri ndeye "Chii Chandinofanira Kudya Zvakasiyana Kubva Kare?" uye masarudzire avanofanira kuita zvekudya uye zvekuwedzera kuti vatarise njodzi dzechirwere. Sezvo kune njodzi yegomarara hapana chinogoneka maererano nekurapa - sarudzo dzezvekudya uye zvekuwedzera zvinove zvakakosha uye chimwe chezvinhu zvishoma zvingaite zvinogona kuitwa. Zvese zvinodyarwa-zvikafu hazvina kuenzana uye zvichibva pane zvakazivikanwa genetics uye nzira siginecha - sarudzo dzechikafu nekuwedzera dzinofanirwa kuve munhu.

Sarudza Vegetable GIANT BUTTERBUR kana GARDEN RHUBARB?

Vegetable Giant Butterbur ine zvakawanda zvinoshanda zvinosanganisa kana bioactives zvakaita seCurcumin, Apigenin, Formononetin, Lycopene, Lupeol. Izvi zvinoshandiswa zvinoshandiswa zvinoshandisa nzira dzakasiyana dzebiochemical seApoptosis, JAK-STAT Signaling, PI3K-AKT-MTOR Signaling uye P53 Signaling nevamwe. Giant Butterbur inokurudzirwa kune njodzi yeChondroblastic Osteosarcoma kana yakabatana genetic njodzi iri BCOR. Izvi zvinodaro nekuti Giant Butterbur inowedzera idzo biochemical nzira dzinopokana nemadhiraivha emasaini ayo.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuriwo Bindu Rhubarb ndeye Curcumin, Apigenin, Quercetin, Emodin, Rhein. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seGlutathione Metabolism uye vamwe. Gadheni Rhubarb harikurudzirwe kana njodzi yeChondroblastic Osteosarcoma kana yakabatana genetic njodzi iri BCOR nekuti inowedzera siginecha nzira dzayo.

MURIWO MHOMBE BUTTERBUR INOKURUKURWA PAMUSORO PAMUSORO PEGArden RHUBARB YEBCOR GENETIC RISK YECANCER.

Sarudza Chibereko NANCE kana GRAPEFRUIT?

Chibereko Nance chine zvakawanda zvinoshanda zvinosanganisa kana bioactives seCurcumin, Apigenin, Formononetin, Lupeol, Delphinidin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical sePI3K-AKT-MTOR Signaling, Hypoxia uye P53 Signaling nevamwe. Nance inokurudzirwa kune njodzi yeChondroblastic Osteosarcoma kana yakabatana genetic njodzi iri BCOR. Izvi zvinodaro nekuti Nance inowedzera idzo biochemical nzira dzinopokana nemadhiraivha emasaini ayo.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuchero Grapefruit ndeye Curcumin, Formononetin, Lycopene, Lupeol, Delphinidin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seGlutathione Metabolism uye vamwe. Grapefruit haikurudzirwe kana njodzi yeChondroblastic Osteosarcoma kana yakabatana genetic njodzi iri BCOR nekuti inowedzera siginecha nzira dzayo.

FRUIT NANCE INOKURUDZWA PAMUSORO PERAPEFRUIT YEBCOR GENETIC RISK OF CANCER.

Sarudza Nut BUTTERNUT kana PILI NUT?

Butternut ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seCurcumin, Apigenin, Formononetin, Lycopene, Lupeol. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical nzira seJAK-STAT Signaling, PI3K-AKT-MTOR Signaling, Growth Factor Signaling uye Apoptosis nevamwe. Butternut inokurudzirwa panjodzi yeChondroblastic Osteosarcoma kana njodzi yemajini yakabatana iri BCOR. Izvi zvinodaro nekuti Butternut inowedzera idzo nzira dzebiochemical dzinopesana nemadhiraivha ayo.

Zvimwe zvezvinhu zvinoshanda kana bioactives muPili Nut ndeye Curcumin, Apigenin, Formononetin, Lycopene, Lupeol. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seGlutathione Metabolism uye Oncogenic Cancer Epigenetics nevamwe. Pili Nut haikurudzirwe kana njodzi yeChondroblastic Osteosarcoma kana yakabatana genetic njodzi iri BCOR nekuti inowedzera siginecha nzira dzayo.

BUTTERNUT INOKURUDZWA PAMUSORO PILI NUT YEBCOR GENETIC RISK YECANCER.

Mhedziso

Chikafu uye Zvekuwedzera zvakasarudzwa sarudzo dzakakosha dzegomarara seChondroblastic Osteosarcoma. Chondroblastic Osteosarcoma varwere uye vanhu vane genetic-njodzi vanogara vaine mubvunzo uyu: "Ndezvipi zvekudya uye zvinovaka muviri zvinokurudzirwa kwandiri uye izvo zvisiri?" Pane chitendero chakajairika chinova fungidziro isiriyo yekuti zvese zvinodyarwa-zvikafu zvinogona kubatsira kana kwete asi zvisingakuvadze. Zvimwe zvekudya uye zvekuwedzera zvinogona kukanganisa marapirwo egomarara kana kusimudzira mamorekuru enzira yegomarara.

Kune marudzi akasiyana ezviratidzo zvegomarara seChondroblastic Osteosarcoma, imwe neimwe iine bundu genetics ine mamwe ma genomic akasiyana pamunhu wega wega. Kuwedzera kurapwa kwegomarara uye chemotherapy ine yakasarudzika nzira yekuita. Chikafu chega chega senge Wild Leek chine akasiyana bioactive muhuwandu hwakasiyana, izvo zvine chekuita neakasiyana uye akasiyana seti yebiochemical nzira. Tsanangudzo yekudya yakasarudzika ndeyakasarudzika chikafu kurudziro yegomarara chiratidzo, marapirwo, genetics, mararamiro uye zvimwe zvinhu. Sarudzo dzehutano hwemunhu hwegomarara dzinoda ruzivo rwegomarara biology, sainzi yechikafu uye kunzwisisa kweakasiyana chemotherapy marapirwo. Chekupedzisira kana paine shanduko yekurapa kana nyowani genomics inoonekwa - iyo inovaka muviri inoda kuongororwazve.

Iyo addon nutrition personalization solution inoita kuti sarudzo ive nyore uye inobvisa zvese zvekufungidzira mukupindura mubvunzo, "Ndezvipi zvekudya zvandinofanira kusarudza kana kusasarudza Chondroblastic Osteosarcoma?". Iyo addon yakawanda-yekuranga timu inosanganisira varapi vegomarara, masayendisiti ekiriniki, mainjiniya esoftware uye masayendisiti edata.

References

• Pan Yakatangwa 2020
• Mutational landscape yekenza yemetastatic yakaratidzwa kubva kune vangangove vanotarisirwa kutevedzana kwevarwere zviuru gumi.
• Anti-Metastatic Effects yeLupeol kuburikidza neInhibition yeMAPK / ERK Pathway muLung Cancer.
• Retinol inoderedza beta-catenin mapuroteni mazinga mu retinoic acid-inodzivirira colon cancer cell mitsara.
• Formononetin inodzvinyirira kuwanda kwegomarara remapapu revanhu risiri diki kuburikidza nekuiswa kwesero cycle kusungwa uye apoptosis.