Zvokudya zveAnorectal Mucosal Melanoma!

ziviso

Zvikafu zveAnorectal Mucosal Melanoma zvinofanirwa kuve zvakasarudzika kune wega wega uye zvakare zvinofanirwa kuchinjika kana kenza kurapwa kana bundu genetic shanduko. Iyo yemunhu uye kugadzirisa kunofanirwa kufunga nezvese zvinoshanda zvinosanganiswa kana bioactives zviri muzvokudya zvakasiyana zvine chekuita negomarara biology, genetics, marapirwo, mararamiro uye zvido zvekudya. Saka nepo chikafu chiri chimwe chezvisarudzo zvakakosha zvemurwere wegomarara uye munhu ari panjodzi yegomarara - kusarudza chikafu chekudya harisi basa riri nyore.

Kune Anorectal Mucosal Melanoma zvine basa here kuti miriwo, michero, nzungu, mhodzi munhu anodya chii?

Mubvunzo wakajairika wekudya unobvunzwa nevarwere vegomarara uye vanhu vari pa-genetic njodzi yegomarara ndeye - kumakonza akaita seAnorectal Mucosal Melanoma zvine basa here kuti ndechipi chikafu chandinodya uye chandisingade? Kana kuti ndikatevera kudya-kwekudyara kunokwana kenza seAnorectal Mucosal Melanoma?

Semuenzaniso zvine basa here kana muriwo Wax Gourd uchidyiwa zvakanyanya zvichienzaniswa neBroccoli? Zvinoita mutsauko here kana muchero Fox Grape uchisarudzwa pane Red Raspberry? Zvakare kana sarudzo dzakafanana dzikaitirwa nzungu/mhodzi dzakaita seHazelnut pamusoro peBrazil Nut uye yemapuruzi akaita seBlack-eyed Pea pamusoro peGram Bean. Uye kana izvo zvandinodya zvine basa - zvino munhu angaziva sei zvikafu zvinokurudzirwa Anorectal Mucosal Melanoma uye ndiyo mhinduro imwechete kune wese ane chirwere chakafanana kana genetic njodzi?

Ehe! Zvokudya zvaunodya zvine chekuita neAnorectal Mucosal Melanoma!

Mazano echikafu anogona kunge asina kufanana kune wese munhu uye anogona kuve akasiyana kunyangwe kune imwechete kuongororwa uye genetic njodzi.

Zvokudya zvose (miriwo, michero, nzungu, mhodzi, pulses, mafuta nezvimwewo) uye zvokudya zvinovaka muviri zvinoumbwa nezvinodarika imwe inoshanda mamolecular ingredient kana bio-actives muzvikamu zvakasiyana uye uwandu. Chinhu chimwe nechimwe chinoshanda chine nzira yakasarudzika yekuita - iyo inogona kuve activation kana inhibition yeakasiyana biochemical nzira. Zvikafu zvakangotaurwa uye zvekuwedzera izvo zvinokurudzirwa ndezviya zvisingakonzere kuwedzera kwemamorekuru anotyaira cancer asi anodzideredza. Zvikasadaro izvo zvikafu hazvifanirwe kukurudzirwa. Chikafu chine akawanda anoshanda zvinongedzo - saka kana uchiongorora chikafu uye zvekuwedzera iwe unofanirwa kufunga nezve mabatiro ezvese zvinoshanda zvinongedzo zvakapetwa kwete zvega.

Semuenzaniso Fox Mazambiringa ane zvinoshanda zvinosanganisa Apigenin, Curcumin, Quercetin, Myricetin, Isoliquiritigenin. Uye Red Raspberry ine inoshanda zvinoshandiswa Ellagic Acid, Curcumin, Quercetin, Isoliquiritigenin, Lupeol uye pamwe nevamwe.

Chikanganiso chinowanzoitwa pakusarudza nekusarudza chikafu chekudya cheAnorectal Mucosal Melanoma - kuongorora chete zvakasarudzwa zvinoshandiswa zviri muzvokudya uye kufuratira zvimwe. Nekuti zvakasiyana-siyana zvinoshanda zviri mukudya zvinogona kuva nemhedzisiro inopikisa kune vatyairi vegomarara - haugone kutora cherry zvinoshanda muzvikafu uye zvinowedzera kuita sarudzo yekudya kune Anorectal Mucosal Melanoma.

HONGU – ZVOKUSARUDZA ZVOKUDYA ZVINOKOSHA NEGONSA. ZVISARUDZO ZVOKUDYA ZVINOFANIRA KUFUNGA ZVINHU ZVINHU ZVINHU ZVINOSHANDA PACHIDYA.

Unyanzvi hunodiwa paKudya Kwekudya Kwemunhu kune Anorectal Mucosal Melanoma?

Kudya kwakasarudzika kwegomarara seAnorectal Mucosal Melanoma ine zvinokurudzirwa zvekudya / zvinowedzera; zvisingakurudzirwe chikafu / ma supplements ane semuenzaniso mabikirwo anotungamira kushandiswa kwezvikafu zvinokurudzirwa. Muenzaniso wekudya kwakasiyana-siyana unogona kuonekwa pane izvi batanidzo.

Kufunga kuti ndezvipi zvekudya zvinokurudzirwa kana kwete zvakaomesesa, zvinoda hunyanzvi muAnorectal Mucosal Melanoma biology, sainzi yechikafu, genetics, biochemistry pamwe nekunzwisisa kwakanaka kwemashandiro anoita marapirwo egomarara uye kusagadzikana kwakabatana uko kurapwa kwaigona kumira kushanda.

ZVINONYANYA ZVINONYANYA ZVINODIWA KUTI ZVINOVAKA ZVINOVAKA MUNHU ZVINHU ZVINHU ZVINOITA: CANCER BIOLOGY, FOOD SCIENCE, KURAPA MAKANZA UYE GENETICS.

Hunhu hwegomarara seAnorectal Mucosal Melanoma

Ese magomarara seAnorectal Mucosal Melanoma anogona kuratidzirwa neyakasiyana seti yebiochemical nzira - iyo siginecha nzira dzeAnorectal Mucosal Melanoma. Nzira dzeBiochemical dzakadai sePI3K-AKT-MTOR Chiratidzo, Amino Acid Metabolism, RAS-RAF Signaling, MAPK Signaling chikamu chetsanangudzo yeAnorectal Mucosal Melanoma. Kenza yemunhu wega genetics inogona kuve yakasiyana uye nekudaro siginicha yavo yegomarara inogona kuve yakasarudzika.

Mishonga iyo inoshanda kune Anorectal Mucosal Melanoma inofanirwa kuziva iyo inosanganisirwa siginecha biochemical nzira kune yega yega murwere wegomarara uye munhu ari panjodzi yemajini. Saka marapirwo akasiyana ane maitiro akasiyana ezviito anoshanda kune varwere vakasiyana. Saizvozvo uye nekuda kwezvikonzero zvakafanana zvekudya uye zvekuwedzera zvinoda kuitirwa munhu wega wega. Saka zvimwe zvekudya uye zvekuwedzera zvinokurudzirwa kune Anorectal Mucosal Melanoma kana uchitora kenza kurapwa Belinostat, uye zvimwe zvekudya uye zvinowedzera hazvikurudzirwe.

Sources like cBioPortal uye vamwe vazhinji vanopa mumiriri wehuwandu hwevarwere data risingazivikanwe kubva kukiriniki miedzo yezvese zviratidzo zvegomarara. Iyi dhata ine yekiriniki yekuongorora yeruzivo senge sampuli saizi / nhamba yevarwere, mapoka ezera, murume kana mukadzi, dzinza, marapirwo, bundu saiti uye chero genetic mutations.

SF3B1, NF1, KIT, TP53 neNRAS ndiwo emhando yepamusoro akashumwa majini eAnorectal Mucosal Melanoma. SF3B1 inoshumwa mu 27.5% yevanomiririra varwere mumakiriniki ese ekuedzwa. Uye NF1 inoshumwa mu20.3%. Iyo yakasanganiswa yehuwandu hwevarwere data inovhara mazera kubva kusvika . 44.9% yedata revarwere vanoonekwa sevarume. Iyo Anorectal Mucosal Melanoma biology pamwe neyakashumwa genetics pamwe chete inotsanangura huwandu hwevanhu vanomiririrwa siginecha biochemical nzira dzegomarara iri. Kana iyo yega cancer tumor genetics kana majini anokonzera njodzi achizivikanwawo saka izvo zvinofanirwa kushandiswawo kune hutano hwemunhu.

ZVAKASARUDZA KUDYA ZVINODYA ZVINOFANIRA KUFANIRA NEMUNHU WEMUNHU WEMUNHU WEMUNHU WEGONSI.

Chikafu uye Zvekuwedzera zveAnorectal Mucosal Melanoma

Kune Varwere veCancer

Varwere vegomarara vari pakurapa kana pakuchengeta palliative vanofanira kuita sarudzo pazvekudya uye zvekuwedzera - zvemacalorie anodiwa ekudya, kubata chero mhedzisiro yekurapa uyezve nekugadzirisa kenza. Zvese zvinodyarwa-zvikafu hazvina kuenzana uye kusarudza uye kuisa pamberi pezvikafu zvakagadzirirwa munhu uye zvakagadzirirwa kuenderera mberi kurapwa kwegomarara kwakakosha uye kwakaoma. Heano mimwe mienzaniso inopa nhungamiro yekuita sarudzo dzekudya.

Sarudza Vegetable WAX ​​GOURD kana BROCCOLI?

Vegetable Wax Gourd ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seApigenin, Curcumin, Myricetin, Isoliquiritigenin, Lupeol. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical senge RAS-RAF Signaling, JAK-STAT Signaling, PI3K-AKT-MTOR Signaling uye DNA Kugadzirisa uye vamwe. Wax Gourd inokurudzirwa kuAnorectal Mucosal Melanoma apo chirwere chegomarara chiri kuramba chiri Belinostat. Izvi zvinodaro nekuti Wax Gourd inogadzirisa idzo nzira dzebiochemical dzakataurwa nesainzi kuti dzigonese mashandiro eBelinostat.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuriwo Broccoli ndeye Curcumin, Quercetin, Isoliquiritigenin, Lupeol, Resveratrol. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seOxidative Stress uye DNA Kugadzirisa uye vamwe. Broccoli haikurudzirwe kune Anorectal Mucosal Melanoma kana kurapwa kwegomarara kuri kuenderera mberi kuri Belinostat nekuti inogadzirisa idzo biochemical nzira dzinoita kuti kurapwa kwegomarara risarambe kana kusadaira.

MURIWO WAX GOURD INOKURUDZWA PAMUSORO PEBROCCOLI YEAnorectal Mucosal Melanoma UYE KURAPA Belinostat.

Sarudza Muchero RED RASPBERRY kana FOX GRAPE?

Chibereko Chitsvuku Raspberry chine zvakawanda zvinoshanda zvinosanganisa kana bioactives seEllagic Acid, Curcumin, Quercetin, Isoliquiritigenin, Lupeol. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical senge Oxidative Stress, JAK-STAT Signaling, PI3K-AKT-MTOR Kuratidzira uye Amino Acid Metabolism nevamwe. Red Raspberry inokurudzirwa kune Anorectal Mucosal Melanoma apo inoenderera mberi kurapwa kwegomarara iri Belinostat. Izvi zvinodaro nekuti Red Raspberry inogadzirisa idzo biochemical nzira dzakataurwa nesainzi kuti dzikurudzire mhedzisiro yeBelinostat.

Zvimwe zvezvishandiso zvinoshandiswa kana bioactives mumuchero Fox Grape ndeye Apigenin, Curcumin, Quercetin, Myricetin, Isoliquiritigenin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seOxidative Stress uye DNA Kugadzirisa uye vamwe. Fox Grape haikurudzirwe kune Anorectal Mucosal Melanoma kana ichienderera mberi kurapwa kwegomarara iri Belinostat nekuti inogadzirisa idzo biochemical nzira dzinoita kuti kurapwa kwegomarara kumire kana kusadaira.

MUCHERO RED RASPBERRY INOKURUDZWA PAMUSORO PAMUSORO PEFOX MABHIPI YEAnorectal Mucosal Melanoma UYE KURAPA Belinostat.

Sarudza Nut HAZELNUT kana BRAZIL NUT?

Hazelnut ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seApigenin, Curcumin, Myricetin, Isoliquiritigenin, Lupeol. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical senge Amino Acid Metabolism, JAK-STAT Signaling, PI3K-AKT-MTOR Kuratidzira uye Hypoxia nevamwe. Hazelnut inokurudzirwa kuAnorectal Mucosal Melanoma apo chirwere chegomarara chiri kuramba chiri Belinostat. Izvi zvinodaro nekuti Hazelnut inogadzirisa idzo nzira dzebiochemical dzakataurwa nesainzi kuti dzikurudzire kuita kweBelinostat.

Zvimwe zvezvinhu zvinoshanda kana bioactives muBrazil Nut ndeye Ellagic Acid, Curcumin, Isoliquiritigenin, Lupeol, Daidzein. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical senge Oxidative Stress, JAK-STAT Signaling uye PI3K-AKT-MTOR Kuratidzira uye vamwe. Brazil Nut haikurudzirwe kune Anorectal Mucosal Melanoma kana ichiramba ichirapwa kenza iri Belinostat nekuti inogadzirisa idzo biochemical nzira dzinoita kuti kurapwa kwegomarara risarambe kana kusadaira.

HAZELNUT INOKURUDZIRWA PAMUSORO PEBRAZIL NUT YEAnorectal Mucosal Melanoma UYE KURAPA Belinostat.

Kune Vanhu Vane Genetic Risk yeCancer

Mubvunzo wakabvunzwa nevanhu vane genetic risk yeAnorectal Mucosal Melanoma kana nhoroondo yemhuri ndeye "Chii Chandinofanira Kudya Zvakasiyana Kubva Kare?" uye masarudzire avanofanira kuita zvekudya uye zvekuwedzera kuti vatarise njodzi dzechirwere. Sezvo kune njodzi yegomarara hapana chinogoneka maererano nekurapa - sarudzo dzezvekudya uye zvekuwedzera zvinove zvakakosha uye chimwe chezvinhu zvishoma zvingaite zvinogona kuitwa. Zvese zvinodyarwa-zvikafu hazvina kuenzana uye zvichibva pane zvakazivikanwa genetics uye nzira siginecha - sarudzo dzechikafu nekuwedzera dzinofanirwa kuve munhu.

Sarudza Vegetable CAULIFLOWER kana CHINESE MUSTARD?

Vegetable Cauliflower ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seCurcumin, Formononetin, Lupeol, Daidzein, Isoliquiritigenin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana-siyana dzebiochemical seApoptosis, PI3K-AKT-MTOR Kuratidzira, MAPK Kusaina uye P53 Kuratidzira nevamwe. Koliflower inokurudzirwa kune njodzi yeAnorectal Mucosal Melanoma kana yakabatana neiyo genetic njodzi iKIT. Izvi zvinodaro nekuti Cauliflower inowedzera idzo nzira dzebiochemical dzinopokana nemadhiraivha ayo anosaina.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuriwo Chinese Mustard ndeye Apigenin, Curcumin, Quercetin, Formononetin, Lupeol. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical sePI3K-AKT-MTOR Kuratidzira uye Oncogenic Cancer Epigenetics nevamwe. Chinese Mustard haikurudzirwe kana njodzi yeAnorectal Mucosal Melanoma kana yakabatana genetic njodzi iri KIT nekuti inowedzera siginecha nzira dzayo.

VEGETABLE CAULIFLOWER INAKURUDZIRWA PAMUSORO PECHINESE MUSTARD YEKIT GENETIC RISK YECANCER.

Sarudza Chibereko NANCE kana PUMMELO?

Chibereko Nance chine zvakawanda zvinoshanda zvinosanganisa kana bioactives seApigenin, Curcumin, Formononetin, Lupeol, Myricetin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana-siyana dzebiochemical seAngiogenesis, JAK-STAT Signaling, PI3K-AKT-MTOR Signaling uye P53 Signaling nevamwe. Nance inokurudzirwa kune njodzi yeAnorectal Mucosal Melanoma kana yakabatana genetic njodzi iri KIT. Izvi zvinodaro nekuti Nance inowedzera idzo biochemical nzira dzinopokana nemadhiraivha emasaini ayo.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuchero Pummelo ndeye Apigenin, Curcumin, Quercetin, Formononetin, Lycopene. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical seSero Cycle Checkpoints, PI3K-AKT-MTOR Signaling uye MYC Signaling nevamwe. Pummelo haikurudzirwe kana njodzi yeAnorectal Mucosal Melanoma kana yakabatana genetic njodzi iri KIT nekuti inowedzera siginecha nzira dzayo.

FRUIT NANCE INOKURUDZWA PAMUSORO PAPUMMELO YEKIT GENETIC RISK YECANCER.

Sarudza Nut COMMON HAZELNUT kana CHESTNUT?

Common Hazelnut ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seCurcumin, Quercetin, Formononetin, Lycopene, Lupeol. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical seAngiogenesis, JAK-STAT Signaling, PI3K-AKT-MTOR Kuratidzira uye Kukura Factor Signaling nevamwe. Common Hazelnut inokurudzirwa kune njodzi yeAnorectal Mucosal Melanoma kana yakabatana genetic njodzi iri KIT. Izvi zvinodaro nekuti Common Hazelnut inowedzera idzo biochemical nzira dzinopokana nemadhiraivha emasaini ayo.

Zvimwe zvezvinhu zvinoshanda kana bioactives muChestnut ndeye Apigenin, Curcumin, Ellagic Acid, Formononetin, Lycopene. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical sePI3K-AKT-MTOR Kuratidzira uye Oncogenic Cancer Epigenetics nevamwe. Chestnut haikurudzirwe kana njodzi yeAnorectal Mucosal Melanoma kana yakabatana genetic njodzi iri KIT nekuti inowedzera siginecha nzira dzayo.

COMMON HAZELNUT INOKURUDZWA PAMUSORO PACHESTNUT YEKIT GENETIC RISK YECANCER.

Mhedziso

Chikafu uye Zvekuwedzera zvakasarudzwa sarudzo dzakakosha kune cancer seAnorectal Mucosal Melanoma. Anorectal Mucosal Melanoma varwere uye vanhu vane genetic-njodzi vanogara vaine mubvunzo uyu: "Ndezvipi zvekudya uye zvinovaka muviri zvinokurudzirwa kwandiri uye izvo zvisiri?" Pane chitendero chakajairika chinova fungidziro isiriyo yekuti zvese zvinodyarwa-zvikafu zvinogona kubatsira kana kwete asi zvisingakuvadze. Zvimwe zvekudya uye zvekuwedzera zvinogona kukanganisa marapirwo egomarara kana kukurudzira mamorekuru enzira yegomarara.

Kune marudzi akasiyana ezviratidzo zvegomarara seAnorectal Mucosal Melanoma, imwe neimwe iine bundu genetics ine mamwe ma genomic akasiyana pamunhu wega wega. Kuwedzera kurapwa kwegomarara uye chemotherapy ine yakasarudzika nzira yekuita. Chikafu chega chega seWax Gourd chine mabioactive akasiyana muhuwandu hwakasiyana, izvo zvine chekuita nenzira dzakasiyana uye dzakasiyana dzebiochemical nzira. Tsanangudzo yekudya yakasarudzika ndeyakasarudzika chikafu kurudziro yegomarara chiratidzo, marapirwo, genetics, mararamiro uye zvimwe zvinhu. Sarudzo dzehutano hwemunhu hwegomarara dzinoda ruzivo rwegomarara biology, sainzi yechikafu uye kunzwisisa kweakasiyana chemotherapy marapirwo. Chekupedzisira kana paine shanduko yekurapa kana nyowani genomics inoonekwa - iyo inovaka muviri inoda kuongororwazve.

Iyo addon nutrition personalization solution inoita kuti sarudzo ive nyore uye inobvisa zvese zvekufungidzira mukupindura mubvunzo, "Ndezvipi zvekudya zvandinofanira kusarudza kana kusasarudzira Anorectal Mucosal Melanoma?". Iyo addon yakawanda-yekuranga timu inosanganisira varapi vegomarara, masayendisiti ekiriniki, mainjiniya esoftware uye masayendisiti edata.

References

• Tmb Mskcc 2018
• Mutational landscape yekenza yemetastatic yakaratidzwa kubva kune vangangove vanotarisirwa kutevedzana kwevarwere zviuru gumi.
• BRCA1 uye BRCA2 sema molecular targets for phytochemicals indole-3-carbinol uye genistein mumazamu nekenza yeprostate.
• Mhedzisiro ye isoliquiritigenin pamasero egomarara reovarian.
• Inhibitory mhedzisiro yeHibiscus protocatechuic acid pakusimudzira tumor muganda regonzo.
• Mhedzisiro uye kukosha kweformononetin pamatanho ekutaura eHIF-1α uye VEGF mune mbeva yecervical cancer tissue.
• Kudzivirira mhedzisiro yebutyric acid, nicotinamide, calcium glucarate yoga kana musanganiswa panguva ye7, 12-dimethylbenz (a) anthracene induced mouse skin tumorigenesis kuburikidza nemodulation yeK-Ras-PI3K-AKTpathway uye yakabatana micro RNAs.