Zvokudya zveSinonasal Adenocarcinoma!

ziviso

Zvikafu zveSinonasal Adenocarcinoma zvinofanirwa kuve zvakasarudzika kune wega wega uye zvakare zvinofanirwa kuchinjika kana kenza kurapwa kana bundu genetic shanduko. Iyo yemunhu uye kugadzirisa kunofanirwa kufunga nezvese zvinoshanda zvinosanganiswa kana bioactives zviri muzvokudya zvakasiyana zvine chekuita negomarara biology, genetics, marapirwo, mararamiro uye zvido zvekudya. Saka nepo chikafu chiri chimwe chezvisarudzo zvakakosha zvemurwere wegomarara uye munhu ari panjodzi yegomarara - kusarudza chikafu chekudya harisi basa riri nyore.

Kune Sinonasal Adenocarcinoma zvine basa here kuti miriwo, michero, nzungu, mhodzi munhu anodya chii?

Mubvunzo wakajairika wekudya unobvunzwa nevarwere vegomarara uye vanhu vari pa-genetic njodzi yegomarara ndeye - kumakonza akaita seSinonasal Adenocarcinoma zvine basa here kuti ndechipi chikafu chandinodya uye chandisingade? Kana kuti kana ndikatevera kudya-kwekudyara kunokwana kenza seSinonasal Adenocarcinoma?

Semuenzaniso zvine basa here kana muriwo Thistle uchidyiwa zvakanyanya kana uchienzaniswa neChinese Broccoli? Pane mutsauko here kana muchero Pitanga uchifarirwa pane Pomegranate? Zvakare kana sarudzo dzakafanana dzakaitirwa nzungu/mhodzi dzakaita seWalnut pamusoro peMacadamia Nut uye nemapuruzi seSoy Bean pamusoro peCommon Pea. Uye kana izvo zvandinodya zvine basa - zvino munhu angaziva sei zvikafu zvinokurudzirwa kuSinonasal Adenocarcinoma uye ndiyo mhinduro imwechete kune wese ane chirwere chakafanana kana genetic njodzi?

Ehe! Zvokudya zvaunodya zvine chekuita neSinonasal Adenocarcinoma!

Mazano echikafu anogona kunge asina kufanana kune wese munhu uye anogona kuve akasiyana kunyangwe kune imwechete kuongororwa uye genetic njodzi.

Zvokudya zvose (miriwo, michero, nzungu, mhodzi, pulses, mafuta nezvimwewo) uye zvokudya zvinovaka muviri zvinoumbwa nezvinodarika imwe inoshanda mamolecular ingredient kana bio-actives muzvikamu zvakasiyana uye uwandu. Chinhu chimwe nechimwe chinoshanda chine nzira yakasarudzika yekuita - iyo inogona kuve activation kana inhibition yeakasiyana biochemical nzira. Zvikafu zvakangotaurwa uye zvekuwedzera izvo zvinokurudzirwa ndezviya zvisingakonzere kuwedzera kwemamorekuru anotyaira cancer asi anodzideredza. Zvikasadaro izvo zvikafu hazvifanirwe kukurudzirwa. Chikafu chine akawanda anoshanda zvinongedzo - saka kana uchiongorora chikafu uye zvekuwedzera iwe unofanirwa kufunga nezve mabatiro ezvese zvinoshanda zvinongedzo zvakapetwa kwete zvega.

Semuenzaniso Pitanga ine zvinhu zvinoshanda Eugenol, Luteolin, Chlorogenic Acid, Lutein, Beta-carotene. Uye Pomegranate ine zvinoshanda zvinosanganisa Corilagin, Eugenol, Luteolin, Linolenic Acid, Lutein uye pamwe nevamwe.

Chikanganiso chinowanzoitwa pakusarudza nekusarudza chikafu chekudya cheSinonasal Adenocarcinoma - kuongorora chete zvakasarudzwa zvinoshandiswa zviri muzvokudya uye kufuratira zvimwe. Nekuti zvakasiyana-siyana zvinoshanda zviri mukudya zvinogona kuva nemhedzisiro inopikisa kune vatyairi vegomarara - haugone kutora cherry inoshanda mukudya uye ma supplements ekuita sarudzo yehutano yeSinonasal Adenocarcinoma.

HONGU – ZVOKUSARUDZA ZVOKUDYA ZVINOKOSHA NEGONSA. ZVISARUDZO ZVOKUDYA ZVINOFANIRA KUFUNGA ZVINHU ZVINHU ZVINHU ZVINOSHANDA PACHIDYA.

Unyanzvi hunodiwa paKudya Kwekudya Kwemunhu kune Sinonasal Adenocarcinoma?

Kudya kwakasarudzika kwegomarara seSinonasal Adenocarcinoma ine zvinokurudzirwa zvekudya / zvinowedzera; zvisingakurudzirwe chikafu / ma supplements ane semuenzaniso mabikirwo anotungamira kushandiswa kwezvikafu zvinokurudzirwa. Muenzaniso wekudya kwakasiyana-siyana unogona kuonekwa pane izvi batanidzo.

Kufunga kuti ndezvipi zvekudya zvinokurudzirwa kana kwete zvakaomesesa, zvinoda hunyanzvi muSinonasal Adenocarcinoma biology, sainzi yechikafu, genetics, biochemistry pamwe nekunzwisisa kwakanaka kwemashandiro anoita marapirwo egomarara uye kusagadzikana kwakabatana uko kurapwa kwaigona kumira kushanda.

ZVINONYANYA ZVINONYANYA ZVINODIWA KUTI ZVINOVAKA ZVINOVAKA MUNHU ZVINHU ZVINHU ZVINOITA: CANCER BIOLOGY, FOOD SCIENCE, KURAPA MAKANZA UYE GENETICS.

Hunhu hwegomarara seSinonasal Adenocarcinoma

Ese magomarara seSinonasal Adenocarcinoma anogona kuratidzirwa neyakasiyana seti yebiochemical nzira - iyo siginecha nzira dzeSinonasal Adenocarcinoma. Nzira dzeBiochemical dzakadai seNotch Signaling, Chromatin Remodeling, RAS-RAF Signaling, Oncogenic Cancer Epigenetics chikamu chetsanangudzo yeSinonasal Adenocarcinoma. Kenza yemunhu wega genetics inogona kuve yakasiyana uye nekudaro siginicha yavo yegomarara inogona kuve yakasarudzika.

Kurapa kunoshanda kweSinonasal Adenocarcinoma kunofanirwa kuve nekuziva kune inosanganisirwa siginecha biochemical nzira kune wega wega cancer murwere uye munhu ari panjodzi yemajini. Saka marapirwo akasiyana ane maitiro akasiyana ezviito anoshanda kune varwere vakasiyana. Saizvozvo uye nekuda kwezvikonzero zvakafanana zvekudya uye zvekuwedzera zvinoda kuitirwa munhu wega wega. Saka zvimwe zvekudya uye zvekuwedzera zvinokurudzirwa kuSinonasal Adenocarcinoma kana uchitora kurapwa kwegomarara Radiation, uye zvimwe zvekudya uye zvekuwedzera hazvikurudzirwe.

Sources like cBioPortal uye vamwe vazhinji vanopa mumiriri wehuwandu hwevarwere data risingazivikanwe kubva kukiriniki miedzo yezvese zviratidzo zvegomarara. Iyi dhata ine yekiriniki yekuongorora yeruzivo senge sampuli saizi / nhamba yevarwere, mapoka ezera, murume kana mukadzi, dzinza, marapirwo, bundu saiti uye chero genetic mutations.

ATRX, TCF3, ARID1A, BRAF uye CTCF ndiwo mazita epamusoro akashumwa majini eSinonasal Adenocarcinoma. ATRX inoshumwa mu 25.0% yevanomiririra varwere mumatambudziko ose emakiriniki. Uye TCF3 inoshumwa mu25.0%. Iyo yakasanganiswa yehuwandu hwevarwere data inovhara mazera kubva kusvika . 100.0% yedata revarwere vanoonekwa sevarume. Iyo Sinonasal Adenocarcinoma biology pamwe neyakashumwa genetics pamwe chete inotsanangura huwandu hwevanhu vanomiririrwa siginecha biochemical nzira dzegomarara iri. Kana iyo yega cancer tumor genetics kana majini anokonzera njodzi achizivikanwawo saka izvo zvinofanirwa kushandiswawo kune hutano hwemunhu.

ZVAKASARUDZA KUDYA ZVINODYA ZVINOFANIRA KUFANIRA NEMUNHU WEMUNHU WEMUNHU WEMUNHU WEGONSI.

Chikafu uye Zvekuwedzera zveSinonasal Adenocarcinoma

Kune Varwere veCancer

Varwere vegomarara vari pakurapa kana pakuchengeta palliative vanofanira kuita sarudzo pazvekudya uye zvekuwedzera - zvemacalorie anodiwa ekudya, kubata chero mhedzisiro yekurapa uyezve nekugadzirisa kenza. Zvese zvinodyarwa-zvikafu hazvina kuenzana uye kusarudza uye kuisa pamberi pezvikafu zvakagadzirirwa munhu uye zvakagadzirirwa kuenderera mberi kurapwa kwegomarara kwakakosha uye kwakaoma. Heano mimwe mienzaniso inopa nhungamiro yekuita sarudzo dzekudya.

Sarudza Vegetable THISTLE kana CHINESE BROCCOLI?

Vegetable Thistle ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seSilibinin, Eugenol, Luteolin, Chlorogenic Acid, Lutein. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seNotch Signaling uye nevamwe. Thistle inokurudzirwa kuSinonasal Adenocarcinoma apo kurapwa gomarara kuri kuramba kuchiitwa Radiation. Izvi zvinodaro nekuti Thistle inogadzirisa idzo nzira dzebiochemical dzakataurwa nesainzi kuti dzikurudzire maitiro eRadiation.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuriwo weChinese Broccoli ndeyeEugenol, Luteolin, Chlorogenic Acid, Lutein, Beta-carotene. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seNotch Signaling uye nevamwe. Chinese Broccoli haikurudzirwe yeSinonasal Adenocarcinoma kana ichiramba ichirapwa cancer iri Radiation nekuti inogadzirisa idzo biochemical nzira dzinoita kuti kurapwa kwegomarara kurambe kana kusadaira.

MURIWO UNO INOKURUDZWA PAMUSORO PAMUSORO PECHINESE BROCCOLI YESinonasal Adenocarcinoma UYE KURAPA Radiation.

Sarudza Muchero POMEGRANATE kana PITANGA?

Muchero Damba rine zvakawanda zvinoshanda zvinosanganisa kana bioactives seCorilagin, Eugenol, Luteolin, Linolenic Acid, Lutein. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seNotch Signaling uye nevamwe. Pomegranate inokurudzirwa kuSinonasal Adenocarcinoma apo kurapwa kwegomarara kuri kuramba kuchiitwa Radiation. Izvi zvinodaro nekuti Damba rinogadzirisa nzira dziya dzebiochemical dzakataurwa nesainzi kuti dzikurudzire kuita kweRadiation.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuchero Pitanga ndeEugenol, Luteolin, Chlorogenic Acid, Lutein, Beta-carotene. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seNotch Signaling uye nevamwe. Pitanga haikurudzirwe kuSinonasal Adenocarcinoma kana ichiramba ichirapwa cancer iri Radiation nekuti inogadzirisa nzira dzebiochemical dziya dzinoita kuti kurapwa kwegomarara risarambe kana kusadaira.

MUCHERO POMEGRANATE INOKURUDZWA PAMUSORO PITANGA YESinonasal Adenocarcinoma UYE KURAPA Radiation.

Sarudza Nut WALNUT kana MACADAMIA NUT?

Walnut ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seCarvacrol, Eugenol, Luteolin, Chlorogenic Acid, Juglone. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seNotch Signaling uye nevamwe. Walnut inokurudzirwa kuSinonasal Adenocarcinoma apo kurapwa kwegomarara kuri kuramba kuchiitwa Radiation. Izvi zvinodaro nekuti Walnut inogadzirisa idzo nzira dzebiochemical dzakataurwa nesainzi kuti dzikurudzire maitiro eRadiation.

Zvimwe zvezvinhu zvinoshanda kana bioactives muMacadamia Nut ndeye Eugenol, Luteolin, Chlorogenic Acid, Lutein, Beta-carotene. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seNotch Signaling uye nevamwe. Macadamia Nut haikurudzirwe yeSinonasal Adenocarcinoma kana ichienderera mberi kurapwa kwegomarara iri Radiation nekuti inogadzirisa idzo biochemical nzira dzinoita kuti kurapwa kwegomarara kumire kana kusadaira.

WALNUT INAKURUDZIRWA PAMUSORO PEMACADAMIA NUT YESinonasal Adenocarcinoma UYE KURAPA Radiation.

Kune Vanhu Vane Genetic Risk yeCancer

Mubvunzo wakabvunzwa nevanhu vane genetic risk yeSinonasal Adenocarcinoma kana nhoroondo yemhuri ndewekuti "Chii Chandinofanira Kudya Zvakasiyana Kubva Kare?" uye masarudzire avanofanira kuita zvekudya uye zvekuwedzera kuti vatarise njodzi dzechirwere. Sezvo kune njodzi yegomarara hapana chinogoneka maererano nekurapa - sarudzo dzezvekudya uye zvekuwedzera zvinove zvakakosha uye chimwe chezvinhu zvishoma zvingaite zvinogona kuitwa. Zvese zvinodyarwa-zvikafu hazvina kuenzana uye zvichibva pane zvakazivikanwa genetics uye nzira siginecha - sarudzo dzechikafu nekuwedzera dzinofanirwa kuve munhu.

Sarudza Vegetable NEW ZEALAND SPINACH kana OSTRICH FERN?

Vegetable New Zealand Sipinachi ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seCurcumin, Apigenin, Lycopene, Lupeol, Beta-sitosterol. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical seSero Cycle, P53 Signaling, MAPK Signaling uye MYC Signaling nevamwe. New Zealand Sipinachi inokurudzirwa panjodzi yeSinonasal Adenocarcinoma kana njodzi yemajini yakabatana iri ARID1A. Izvi zvinodaro nekuti New Zealand Sipinachi inowedzera idzo biochemical nzira dzinopokana nemadhiraivha emasaini ayo.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuriwo Ostrich Fern ndeye Curcumin, Apigenin, Lycopene, Lupeol, Beta-sitosterol. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical seEpithelial kuenda kuMesenchymal Transition uye MAPK Signaling nevamwe. Ostrich Fern haikurudzirwe kana njodzi yeSinonasal Adenocarcinoma kana yakabatana nengozi yemajini iri ARID1A nekuti inowedzera siginicha nzira dzayo.

MURIWO NEW ZEALAND SIPICHI INOKURUDZWA PAMUSORO PEOSTRICH FERN KUTI ARID1A GENETIC RISK YECANCER.

Sarudza Chibereko NANCE kana LINGONBERRY?

Chibereko Nance chine zvakawanda zvinoshanda zvinosanganisa kana bioactives seCurcumin, Apigenin, Lupeol, Beta-sitosterol, Phloretin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical seSero Cycle, P53 Signaling, MAPK Signaling uye MYC Signaling nevamwe. Nance inokurudzirwa kune njodzi yeSinonasal Adenocarcinoma kana yakabatana genetic njodzi iri ARID1A. Izvi zvinodaro nekuti Nance inowedzera idzo biochemical nzira dzinopokana nemadhiraivha emasaini ayo.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuchero Lingonberry ndeye Curcumin, Lycopene, Lupeol, Beta-sitosterol, Phloretin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seEpithelial kuenda kuMesenchymal Transition, P53 Signaling uye WNT Beta Catenin Signaling nevamwe. Lingonberry haikurudzirwe kana njodzi yeSinonasal Adenocarcinoma kana yakabatana genetic njodzi iri ARID1A nekuti inowedzera siginecha nzira dzayo.

FRUIT NANCE INOKURUDZWA PAMUSORO PELINGONBERRY KUARID1A GENETIC RISK YECANCER.

Sarudza Nut BUTTERNUT kana CHESTNUT?

Butternut ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seCurcumin, Apigenin, Lycopene, Lupeol, Beta-sitosterol. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical seSero Cycle, P53 Signaling, MAPK Signaling uye MYC Signaling nevamwe. Butternut inokurudzirwa panjodzi yeSinonasal Adenocarcinoma kana njodzi yemajini yakabatana iri ARID1A. Izvi zvinodaro nekuti Butternut inowedzera idzo nzira dzebiochemical dzinopesana nemadhiraivha ayo.

Zvimwe zvezvinhu zvinoshanda kana bioactives muChestnut ndeye Curcumin, Apigenin, Ellagic Acid, Lycopene, Lupeol. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seEpithelial kuenda kuMesenchymal Transition uye WNT Beta Catenin Signaling nevamwe. Chestnut haikurudzirwe kana njodzi yeSinonasal Adenocarcinoma kana yakabatana genetic njodzi iri ARID1A nekuti inowedzera siginecha nzira dzayo.

BUTTERNUT INOKURUDZWA PAMUSORO PECHESTNUT YEARID1A GENETIC RISK YECANCER.

Mhedziso

Chikafu uye Zvekuwedzera zvakasarudzwa sarudzo dzakakosha dzegomarara seSinonasal Adenocarcinoma. Varwere veSinonasal Adenocarcinoma uye vanhu vane genetic-njodzi vanogara vaine mubvunzo uyu: "Ndezvipi zvekudya uye zvinovaka muviri zvinokurudzirwa kwandiri uye izvo zvisiri?" Pane chitendero chakajairika chinova fungidziro isiriyo yekuti zvese zvinodyarwa-zvikafu zvinogona kubatsira kana kwete asi zvisingakuvadze. Zvimwe zvekudya uye zvekuwedzera zvinogona kukanganisa marapirwo egomarara kana kusimudzira mamorekuru enzira yegomarara.

Kune marudzi akasiyana ezviratidzo zvegomarara seSinonasal Adenocarcinoma, imwe neimwe iine bundu genetics ine mamwe ma genomic musiyano pamunhu wega wega. Kuwedzera kurapwa kwegomarara uye chemotherapy ine yakasarudzika nzira yekuita. Chikafu chega chega senge Thistle chine ma bioactive akasiyana muhuwandu hwakasiyana, izvo zvine chekuita neakasiyana uye akasiyana seti yebiochemical nzira. Tsanangudzo yekudya yakasarudzika ndeyakasarudzika chikafu kurudziro yegomarara chiratidzo, marapirwo, genetics, mararamiro uye zvimwe zvinhu. Sarudzo dzehutano hwemunhu hwegomarara dzinoda ruzivo rwegomarara biology, sainzi yechikafu uye kunzwisisa kweakasiyana chemotherapy marapirwo. Chekupedzisira kana paine shanduko yekurapa kana nyowani genomics inoonekwa - iyo inovaka muviri inoda kuongororwazve.

Iyo addon nutrition personalization mhinduro inoita kuti sarudzo ive nyore uye inobvisa zvese zvekufungidzira mukupindura mubvunzo, "Ndezvipi zvekudya zvandinofanira kusarudza kana kusasarudzira Sinonasal Adenocarcinoma?". Iyo addon yakawanda-yekuranga timu inosanganisira varapi vegomarara, masayendisiti ekiriniki, mainjiniya esoftware uye masayendisiti edata.

References

• Msk Impact 2017
• Mutational landscape yekenza yemetastatic yakaratidzwa kubva kune vangangove vanotarisirwa kutevedzana kwevarwere zviuru gumi.
• Rhamnetin uye cirsiliol inokurudzira radiosensitization uye inhibition ye epithelial-mesenchymal transition (EMT) ne miR-34a-mediated kudzvanywa kweNotch-1 kutaura mune isiri-diki cell kenza yemapapu maseru.
• Eugenol inorambidza Cancer Stem Cell huwandu nekuderedzwa kwe β-catenin kuburikidza neN-terminal Ser37 phosphorylation-an in vivo uye in vitro yekuedza kuongorora.
• Kukura kwekukurudzira kwemasero emunhu pulmonary adenocarcinoma uye madiki epithelial masero emhepo ne beta-carotene kuburikidza ne activation ye cAMP, PKA, CREB uye ERK1/2.
• Corilagin inodzvinyirira cholangiocarcinoma kufambira mberi kuburikidza neNotch kusaina nzira mu vitro uye mu vivo.
• Silybin-mediated inhibition yeNotch signing inoshandisa antitumor chiitiko mumasero emunhu hepatocellular carcinoma.
• Carvacrol Induced Program Cell Death uye Cell Cycle Kusungwa muAndrogen-Yakazvimirira Human Prostate Cancer Cells kuburikidza neInhibition yeNotch Signaling.
• Paederia foetida induces anticancer chiitiko nekugadzirisa chromatin modification enzymes uye kushandura pro-inflammatory cytokine gene kutaura mumunhu masero ekenza yeprostate.
• Dziviriro inopesana nekusimudzira mhedzisiro yeti chena uye caffeine paPhIP-induced tumorigenesis uye beta-catenin kutaura mugonzo.
• Lycopene zvakasiyana-siyana inokonzera quiescence uye apoptosis mune androgen-inopindura uye -yakazvimirira prostate cancer cell mitsara.