Zvokudya zveRetinoblastoma!

ziviso

Zvikafu zveRetinoblastoma zvinofanirwa kuve zvakasarudzika kune wega wega uye zvakare zvinofanirwa kuchinjika kana kenza kurapwa kana bundu genetic shanduko. Iyo yemunhu uye kugadzirisa kunofanirwa kufunga nezvese zvinoshanda zvinosanganiswa kana bioactives zviri muzvokudya zvakasiyana zvine chekuita negomarara biology, genetics, marapirwo, mararamiro uye zvido zvekudya. Saka nepo chikafu chiri chimwe chezvisarudzo zvakakosha zvemurwere wegomarara uye munhu ari panjodzi yegomarara - kusarudza chikafu chekudya harisi basa riri nyore.

Retinoblastoma igomarara reziso remucheche rinokura muretina. Inokonzerwa nekushanduka kwejene retinoblastoma (RB1) uye inogona kukanganisa rimwe kana maziso ose. Zviratidzo zve retinoblastoma zvinogona kusanganisira leukocoria (pupi yeziso ichiita chena), kuderera kwekuona, uye strabismus (kukanganisa kwemaziso), kurwadziwa, kukura kana kuputika kweziso, ropa riri pamberi pekamuri yeziso kana utachiona, kuzvimba kana kuzvimba kwemaziso. ziso kana nyama yakapoteredza. Kuzivikanwa kwe retinoblastoma red reflex panguva yekuongororwa kwemaziso kwakakosha pakukurumidza kuonekwa. Genetics inoita basa rakakosha mu retinoblastoma, sezvo inogona kugarwa nhaka kana kuitika yega. Nzira dzekurapa retinoblastoma dzinoenderana nekukura kwebundu uye zvinogona kusanganisira chemotherapy, radiation therapy, cryotherapy, uye enucleation (kuvhiya kubviswa kweziso). Kunyatsotevedzera mirairo yekurapa kwakakosha kune mhedzisiro yakanaka. Kufungidzira uye mararamiro ehupenyu anosiyana zvichienderana nezvinhu zvakadai sedanho rechirwere uye kuchinjwa kwemajini chaiwo. Kutungamirirwa kweretinoblastoma kunoda nzira yakasiyana-siyana inosanganisira vana oncologists, ophthalmologists, uye genetic counselors.

Kune Retinoblastoma zvine basa here kuti miriwo, michero, nzungu, mhodzi munhu anodya chii?

Mubvunzo wakajairika wekudya unobvunzwa nevarwere vegomarara uye vanhu vari pa-genetic njodzi yegomarara ndeye - kugomarara senge Retinoblastoma zvine basa here kuti ndechipi chikafu chandinodya uye chandisingade? Kana kuti kana ndikatevera kudya-kwekudyara kunokwana kenza seRetinoblastoma?

Semuyenzaniso zvine basa here kana muriwo Towel Gourd ukadyiwa zvakanyanya uchienzaniswa neAmerican Pokeweed? Zvinoita mutsauko here kana muchero Durian uchifarirwa pane Pomegranate? Zvakare kana sarudzo dzakafanana dzakaitirwa nzungu/mhodzi dzakaita seAlmond pamusoro peEuropean Chestnut uye nemapurusi akaita seLentils pamusoro peCatjang Pea. Uye kana zvandinodya zvine basa - zvino munhu angaziva sei chikafu chinokurudzirwa kuRetinoblastoma uye ndiyo mhinduro imwechete kune wese ane chirwere chakafanana kana genetic njodzi?

Ehe! Zvokudya zvaunodya zvine chekuita neRetinoblastoma!

Mazano echikafu anogona kunge asina kufanana kune wese munhu uye anogona kuve akasiyana kunyangwe kune imwechete kuongororwa uye genetic njodzi.

Zvokudya zvose (miriwo, michero, nzungu, mhodzi, pulses, mafuta nezvimwewo) uye zvokudya zvinovaka muviri zvinoumbwa nezvinodarika imwe inoshanda mamolecular ingredient kana bio-actives muzvikamu zvakasiyana uye uwandu. Chinhu chimwe nechimwe chinoshanda chine nzira yakasarudzika yekuita - iyo inogona kuve activation kana inhibition yeakasiyana biochemical nzira. Zvikafu zvakangotaurwa uye zvekuwedzera izvo zvinokurudzirwa ndezviya zvisingakonzere kuwedzera kwemamorekuru anotyaira cancer asi anodzideredza. Zvikasadaro izvo zvikafu hazvifanirwe kukurudzirwa. Chikafu chine akawanda anoshanda zvinongedzo - saka kana uchiongorora chikafu uye zvekuwedzera iwe unofanirwa kufunga nezve mabatiro ezvese zvinoshanda zvinongedzo zvakapetwa kwete zvega.

Semuenzaniso Durian ine zvinhu zvinoshanda Myricetin, Apigenin, Caffeine, Isoliquiritigenin, Allicin. Uye Pomegranate ine inoshanda zvinosanganisa Myricetin, Apigenin, Oleic Acid, Betulinic Acid, Isoliquiritigenin uye pamwe nevamwe.

Chikanganiso chinowanzoitwa pakusarudza nekusarudza chikafu chekudya cheRetinoblastoma - kuongorora chete zvakasarudzwa zvinoshandiswa zviri muzvokudya uye kufuratira zvimwe. Nekuti zvakasiyana-siyana zvinoshanda zviri mukudya zvinogona kuva nemhedzisiro inopikisa kune vatyairi vegomarara - haugone kutora cherry inoshanda mukudya uye ma supplements ekuita sarudzo yehutano hweRetinoblastoma.

HONGU – ZVOKUSARUDZA ZVOKUDYA ZVINOKOSHA NEGONSA. ZVISARUDZO ZVOKUDYA ZVINOFANIRA KUFUNGA ZVINHU ZVINHU ZVINHU ZVINOSHANDA PACHIDYA.

Hunyanzvi hunodiwa paKudya Kwekudya Kwemunhu kune Retinoblastoma?

Kudya kwakasarudzika kwegomarara senge Retinoblastoma ine zvinokurudzirwa zvekudya / zvinowedzera; zvisingakurudzirwe chikafu / ma supplements ane semuenzaniso mabikirwo anotungamira kushandiswa kwezvikafu zvinokurudzirwa. Muenzaniso wekudya kwakasiyana-siyana unogona kuonekwa pane izvi batanidzo.

Kufunga kuti ndezvipi zvekudya zvinokurudzirwa kana kwete zvakaomesesa, zvinoda hunyanzvi muRetinoblastoma biology, sainzi yechikafu, genetics, biochemistry pamwe nekunzwisisa kwakanaka kwemashandiro anoita marapirwo egomarara uye kusagadzikana kwakabatana uko kurapwa kwaigona kumira kushanda.

ZVINONYANYA ZVINONYANYA ZVINODIWA KUTI ZVINOVAKA ZVINOVAKA MUNHU ZVINHU ZVINHU ZVINOITA: CANCER BIOLOGY, FOOD SCIENCE, KURAPA MAKANZA UYE GENETICS.

Hunhu hwegomarara senge Retinoblastoma

Ese magomarara seRetinoblastoma anogona kuratidzirwa neyakasiyana seti yebiochemical nzira - iyo siginecha nzira dzeRetinoblastoma. Nzira dzeBiochemical seDNA Kugadzirisa, Hypoxia, Cell Cycle, Cell Cycle Checkpoints chikamu chetsanangudzo yeSiginecha yeRetinoblastoma. Kenza yemunhu wega genetics inogona kuve yakasiyana uye nekudaro siginicha yavo yegomarara inogona kuve yakasarudzika.

Kurapa kunoshanda kuRetinoblastoma kunoda kuziva nzira dzakasaina dzebiochemical yemurwere wega wega wegomarara uye munhu ari panjodzi yemajini. Saka marapirwo akasiyana ane maitiro akasiyana ezviito anoshanda kune varwere vakasiyana. Saizvozvo uye nekuda kwezvikonzero zvakafanana zvekudya uye zvekuwedzera zvinoda kuitirwa munhu wega wega. Saka zvimwe zvekudya uye zvekuwedzera zvinokurudzirwa kuRetinoblastoma kana uchitora kurapa cancer Etoposide, uye zvimwe zvekudya uye zvekuwedzera hazvikurudzirwe.

Sources like cBioPortal uye vamwe vazhinji vanopa mumiriri wehuwandu hwevarwere data risingazivikanwe kubva kukiriniki miedzo yezvese zviratidzo zvegomarara. Iyi dhata ine yekiriniki yekuongorora yeruzivo senge sampuli saizi / nhamba yevarwere, mapoka ezera, murume kana mukadzi, dzinza, marapirwo, bundu saiti uye chero genetic mutations.

RB1, CRTC1, BCOR, ABL2 uye SMARCA2 ndiwo mazita epamusoro akataurwa majini eRetinoblastoma. RB1 inoshumwa mu57.8% yevanomiririra varwere mukati meyese miedzo yekiriniki. Uye CRTC1 inoshumwa mu16.7%. Iyo yakasanganiswa yehuwandu hwevarwere data inovhara mazera kubva ku1 kusvika ku21. 52.8 % yedata remurwere inozivikanwa sevarume. Iyo Retinoblastoma biology pamwe neyakashumwa genetics pamwe chete inotsanangura huwandu hwevanhu vanomiririrwa siginecha biochemical nzira dzegomarara iri. Kana iyo yega cancer tumor genetics kana majini anokonzera njodzi achizivikanwawo saka izvo zvinofanirwa kushandiswawo kune hutano hwemunhu.

ZVAKASARUDZA KUDYA ZVINODYA ZVINOFANIRA KUFANIRA NEMUNHU WEMUNHU WEMUNHU WEMUNHU WEGONSI.

Zvokudya uye Zvekuwedzera zveRetinoblastoma

Kune Varwere veCancer

Varwere vegomarara vari pakurapa kana pakuchengeta palliative vanofanira kuita sarudzo pazvekudya uye zvekuwedzera - zvemacalorie anodiwa ekudya, kubata chero mhedzisiro yekurapa uyezve nekugadzirisa kenza. Zvese zvinodyarwa-zvikafu hazvina kuenzana uye kusarudza uye kuisa pamberi pezvikafu zvakagadzirirwa munhu uye zvakagadzirirwa kuenderera mberi kurapwa kwegomarara kwakakosha uye kwakaoma. Heano mimwe mienzaniso inopa nhungamiro yekuita sarudzo dzekudya.

Sarudza Vegetable TOWEL GOURD kana AMERICAN POKEWEED?

Vegetable Towel Gourd ine zvakawanda zvinoshanda zvinoshandiswa kana bioactives zvakadai seApigenin, Oleic Acid, Isoliquiritigenin, Allicin, Daidzein. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical senge DNA Kugadzirisa, Hypoxia uye PI3K-AKT-MTOR Kuratidzira uye vamwe. Towel Gourd inokurudzirwa kuRetinoblastoma apo chirwere chegomarara chiri kuramba chiri Etoposide. Izvi zvinodaro nekuti Towel Gourd inogadziridza idzo nzira dzebiochemical dzakataurwa nesainzi kuti dzigonese mashandiro eEtoposide.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuriwo weAmerican Pokeweed ndiwo Myricetin, Apigenin, Isoliquiritigenin, Allicin, Daidzein. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical senge DNA Kugadzirisa uye PI3K-AKT-MTOR Kuratidzira uye vamwe. American Pokeweed haikurudzirwe kuRetinoblastoma kana ichiramba ichirapwa gomarara iri Etoposide nekuti inogadzirisa idzo biochemical nzira dzinoita kuti kurapwa kwegomarara kurambe kana kusadaira.

VEGETABLE TOWEL GOURD INOKURUDZWA PAMUSORO PEAMERICAN POKEWEED YERetinoblastoma UYE KURAPA Etoposide.

Sarudza Muchero POMEGRANATE kana DURIAN?

Muchero Damba rine zvinhu zvakawanda zvinoshanda kana bioactives seMyricetin, Apigenin, Oleic Acid, Betulinic Acid, Isoliquiritigenin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical senge Hedgehog Signaling, Hypoxia, DNA Kugadzirisa uye PI3K-AKT-MTOR Kuratidzira uye vamwe. Pomegranate inokurudzirwa kuRetinoblastoma apo chirwere chegomarara chiri kuramba chiri Etoposide. Izvi zvinodaro nekuti Damba rinogadzirisa nzira dziya dzebiochemical dzakataurwa nesainzi kuti dzikurudzire kuita kweEtoposide.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuchero Durian ndeyeMyricetin, Apigenin, Caffeine, Isoliquiritigenin, Allicin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical senge DNA Kugadzirisa uye PI3K-AKT-MTOR Kuratidzira uye vamwe. Durian haikurudzirwe kuRetinoblastoma kana ichienderera mberi kurapwa kwegomarara iri Etoposide nekuti inogadzirisa idzo biochemical nzira dzinoita kuti kurapwa kwegomarara kurambe kana kusadaira.

MUCHERO POMEGRANATE INOKURUDZWA PAMUSORO PADURIAN YERetinoblastoma UYE KURAPA Etoposide.

Sarudza Nut ALMOND kana EUROPEAN CHESTNUT?

Almond ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seOleic Acid, Isoliquiritigenin, Allicin, Daidzein, Curcumin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical senge Hypoxia uye PI3K-AKT-MTOR Kuratidzira uye vamwe. Almond inokurudzirwa kuRetinoblastoma apo chirwere chegomarara chiri kuramba chiri Etoposide. Izvi zvinodaro nekuti Almond inogadzirisa idzo nzira dzebiochemical dzakataurwa nesainzi kuti dzikurudzire maitiro eEtoposide.

Zvimwe zvezvinhu zvinoshanda kana bioactives muEuropean Chestnut ndeyeMyricetin, Apigenin, Isoliquiritigenin, Allicin, Daidzein. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical sePI3K-AKT-MTOR Kuratidzira uye vamwe. European Chestnut haikurudzirwe kuRetinoblastoma kana ichienderera mberi kurapwa kwegomarara iri Etoposide nekuti inogadzirisa idzo biochemical nzira dzinoita kuti kurapwa kwegomarara risarambe kana kusadaira.

ALMOND INOKURUDZIRWA KUPINDA YEEUROPA CHESTNUT YERetinoblastoma UYE KURAPA Etoposide.

Kune Vanhu Vane Genetic Risk yeCancer

Mubvunzo wakabvunzwa nevanhu vane genetic risk yeRetinoblastoma kana nhoroondo yemhuri ndeye "Chii Chandinofanira Kudya Zvakasiyana Kubva Kare?" uye masarudzire avanofanira kuita zvekudya uye zvekuwedzera kuti vatarise njodzi dzechirwere. Sezvo panjodzi yegomarara hapana chinoitwa maererano nekurapa - sarudzo dzezvekudya uye zvekuwedzera zvinove zvakakosha uye chimwe chezvinhu zvishoma zvingaite zvinogona kuitwa. Zvese zvinodyarwa-zvikafu hazvina kuenzana uye zvichibva pane zvakazivikanwa genetics uye nzira siginecha - sarudzo dzechikafu nekuwedzera dzinofanirwa kuve munhu.

Sarudza Vegetable CAULIFLOWER kana MUSTARD SPINACH?

Vegetable Cauliflower ine akawanda anoshanda zvinhu kana bioactives akadai Curcumin, Lupeol, Daidzein, Formononetin, Beta-sitosterol. Izvi zvinoshandiswa zvinoshandiswa zvinoshandisa nzira dzakasiyana dzebiochemical seSero Cycle, P53 Signaling, Cell Cycle Checkpoints uye MYC Signaling nevamwe. Koliflower inokurudzirwa kune njodzi yeRetinoblastoma kana njodzi yemajini yakabatana iri ABL2. Izvi zvinodaro nekuti Cauliflower inowedzera idzo nzira dzebiochemical dzinopokana nemadhiraivha ayo anosaina.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuriwo Mustard Sipinachi ndeye Apigenin, Curcumin, Lupeol, Daidzein, Formononetin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical senge DNA Kugadzirisa, PI3K-AKT-MTOR Signaling uye Cell Cycle Checkpoints nevamwe. Mustard Sipinachi haikurudzirwe kana njodzi yeRetinoblastoma kana yakabatana genetic njodzi iri ABL2 nekuti inowedzera siginecha nzira dzayo.

MURIWO KAULIFLOWER INOKURUDZWA PAMUSORO PEMUSTARD SPINACH YEABL2 GENETIC RISK YECANCER.

Sarudza Chibereko NANCE kana PUMMELO?

Chibereko Nance chine zvakawanda zvinoshanda zvinosanganisa kana bioactives seApigenin, Curcumin, Lupeol, Daidzein, Formononetin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical seSero Cycle, P53 Signaling, DNA Repair uye MYC Signaling nevamwe. Nance inokurudzirwa kune njodzi yeRetinoblastoma kana yakabatana genetic njodzi iri ABL2. Izvi zvinodaro nekuti Nance inowedzera idzo biochemical nzira dzinopokana nemadhiraivha emasaini ayo.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuchero Pummelo ndeye Apigenin, Curcumin, Quercetin, Lupeol, Daidzein. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical senge DNA Kugadzirisa, PI3K-AKT-MTOR Signaling uye Cell Cycle Checkpoints nevamwe. Pummelo haikurudzirwe kana njodzi yeRetinoblastoma kana yakabatana genetic njodzi iri ABL2 nekuti inowedzera siginecha nzira dzayo.

FRUIT NANCE INOKURUDZWA PAMUSORO PAMUSORO PAMUSORO PE ABL2 GENETIC RISK YECANCER.

Sarudza Nut COMMON HAZELNUT kana CHESTNUT?

Common Hazelnut ine akawanda anoshanda zvinhu kana bioactives akadai Curcumin, Quercetin, Lupeol, Daidzein, Formononetin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical dzakadai seDNA Kugadzirisa, Cell Cycle, Angiogenesis uye MYC Signaling nevamwe. Common Hazelnut inokurudzirwa kune njodzi yeRetinoblastoma kana njodzi yemajini yakabatana iri ABL2. Izvi zvinodaro nekuti Common Hazelnut inowedzera idzo biochemical nzira dzinopokana nemadhiraivha emasaini ayo.

Zvimwe zvezvinhu zvinoshanda kana bioactives muChestnut ndeye Apigenin, Curcumin, Ellagic Acid, Lupeol, Daidzein. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical senge DNA Kugadzirisa, PI3K-AKT-MTOR Signaling uye Cell Cycle Checkpoints nevamwe. Chestnut haikurudzirwe kana njodzi yeRetinoblastoma kana yakabatana genetic njodzi iri ABL2 nekuti inowedzera siginicha nzira dzayo.

COMMON HAZELNUT INOKUDZWA PAMUSORO PACHESTNUT YEABL2 GENETIC RISK YECANCER.

Mhedziso

Zvokudya uye Zvekuwedzera zvakasarudzwa sarudzo dzakakosha dzegomarara seRetinoblastoma. Varwere veRetinoblastoma uye vanhu vane genetic-njodzi vanogara vaine mubvunzo uyu: "Ndezvipi zvekudya uye zvinovaka muviri zvinokurudzirwa kwandiri uye izvo zvisiri?" Pane chitendero chakajairika chinova fungidziro isiriyo yekuti zvese zvinodyarwa-zvikafu zvinogona kubatsira kana kwete asi zvisingakuvadze. Zvimwe zvekudya uye zvekuwedzera zvinogona kukanganisa marapirwo egomarara kana kusimudzira mamorekuru enzira yegomarara.

Kune marudzi akasiyana ezviratidzo zvegomarara senge Retinoblastoma, imwe neimwe iine bundu genetics ine mamwe ma genomic musiyano pamunhu wega wega. Kuwedzera kurapwa kwegomarara uye chemotherapy ine yakasarudzika nzira yekuita. Chikafu chega chega seTowel Gourd chine ma bioactives akasiyana muhuwandu hwakasiyana, izvo zvine chekuita neakasiyana uye akasiyana seti yebiochemical nzira. Tsanangudzo yekudya yakasarudzika ndeyakasarudzika chikafu kurudziro yegomarara chiratidzo, marapirwo, genetics, mararamiro uye zvimwe zvinhu. Sarudzo dzehutano hwemunhu hwegomarara dzinoda ruzivo rwegomarara biology, sainzi yechikafu uye kunzwisisa kweakasiyana chemotherapy marapirwo. Chekupedzisira kana paine shanduko yekurapa kana nyowani genomics inoonekwa - iyo inovaka muviri inoda kuongororwazve.

Iyo addon nutrition personalization solution inoita kuti sarudzo ive nyore uye inobvisa zvese zvekufungidzira mukupindura mubvunzo, "Ndezvipi zvekudya zvandinofanira kusarudza kana kusasarudzira Retinoblastoma?". Iyo addon yakawanda-yekuranga timu inosanganisira varapi vegomarara, masayendisiti ekiriniki, mainjiniya esoftware uye masayendisiti edata.

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• Sengupta S et al, Indian J Opthalmol., 2016
• https://my.clevelandclinic.org/health/diseases/retinoblastoma
• https://www.ncbi.nlm.nih.gov/books/NBK545276