Zvokudya zveNhetembo Syndrome!

ziviso

Zvokudya zveNhetembo Syndrome zvinofanirwa kuve zvakasarudzika kune wega wega uye zvakare zvinofanirwa kuchinjika kana kenza kurapwa kana bundu genetic shanduko. Iyo yemunhu uye kugadzirisa kunofanirwa kufunga nezvese zvinoshanda zvinosanganiswa kana bioactives zviri muzvokudya zvakasiyana zvine chekuita negomarara biology, genetics, marapirwo, mararamiro uye zvido zvekudya. Saka nepo chikafu chiri chimwe chezvisarudzo zvakakosha zvemurwere wegomarara uye munhu ari panjodzi yegomarara - kusarudza chikafu chekudya harisi basa riri nyore.

Nhetembo chidimbu chinomirira zviratidzo zvishanu zvikuru zvechirwere ichi zvinosanganisira Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal gammopathy uye Skin abnormalities. Ichi chirwere chisingawanzoitiki chinokonzereswa nekusakwana kwekudzivirira kwemuviri nemuviri kune bundu regomarara, umo muviri unorwisa netsaona maseru akajairwa mutsinga. Zvidzidzo zvakataura zvisingaite yakakwira mazinga evascular endothelial growth factor (VEGF) uye pro-inflammatory cytokines muropa revanhu vane POEMS syndrome. POEMS syndrome inoitika 1.5 nguva kakawanda pakati pevarume kupfuura vakadzi uye inowanzoitika kune vanhu vakuru mumakore avo makumi mashanu. Zviratidzo zvakajairika zvePOEMS syndrome zvinosanganisira kupera simba kwetsinga mumawoko nemakumbo, chiropa chakakura zvisina mwero uye / kana spleen, lymph nodes yakakura, kusviba kweganda, kukora kweganda uye kukura kwebvudzi. POEMS syndrome chirwere chisingaperi, uye kufungidzira kwayo kunoenderana nekukura kwechirwere uye mhinduro dzevanhu pakurapwa. Iko hakuna kurapa kwakajairwa kwePOEMS syndrome. Nzira dzekurapa dzinosanganisira radiation therapy, chemotherapy, immune modulatory kana hematopoietic cell transplant. Kupona kwepakati kwevarwere vane POEMS syndrome kunopfuura makore gumi nemana. Kutsigira kutsigirwa nekudya kwakakodzera (zvekudya uye zvechisikigo zvekuwedzera) zvinogonawo kubatsira kuvandudza kugara kwevarwere.

KuNhetembo Syndrome zvine basa here kuti munhu anodyei muriwo, michero, nzungu, mhodzi?

Mubvunzo wakajairika wekudya unobvunzwa nevarwere vegomarara uye vanhu vari pa-genetic njodzi yegomarara ndeye - kumakonza akaita seNhetembo Syndrome zvine basa here kuti ndechipi chikafu chandinodya uye chandisingade? Kana kuti ndikatevera kudya kwezvirimwa kunokwana gomarara seNhetembo Syndrome?

Semuenzaniso zvine basa here kana muriwo Wax Gourd uchidyiwa zvakanyanya zvichienzaniswa neGreen Bell Pepper? Zvinoita mutsauko here kana muchero Pummelo uchifarirwa pane Red Raspberry? Zvakare kana sarudzo dzakafanana dzikaitirwa nzungu/mhodzi dzakaita seHazelnut pamusoro peBrazil Nut uye nezvinomera zvakaita sePea ine maziso matema pamusoro pe Cowpea. Uye kana izvo zvandinodya zvine basa - zvino munhu angaziva sei chikafu chinokurudzirwa Nhetembo Syndrome uye ndiyo mhinduro imwechete kune wese ane chirwere chakafanana kana genetic njodzi?

Ehe! Zvokudya zvaunodya zvine chekuita neNhetembo Syndrome!

Mazano echikafu anogona kunge asina kufanana kune wese munhu uye anogona kuve akasiyana kunyangwe kune imwechete kuongororwa uye genetic njodzi.

Zvokudya zvose (miriwo, michero, nzungu, mhodzi, pulses, mafuta nezvimwewo) uye zvokudya zvinovaka muviri zvinoumbwa nezvinodarika imwe inoshanda mamolecular ingredient kana bio-actives muzvikamu zvakasiyana uye uwandu. Chinhu chimwe nechimwe chinoshanda chine nzira yakasarudzika yekuita - iyo inogona kuve activation kana inhibition yeakasiyana biochemical nzira. Zvikafu zvakangotaurwa uye zvekuwedzera izvo zvinokurudzirwa ndezviya zvisingakonzere kuwedzera kwemamorekuru anotyaira cancer asi anodzideredza. Zvikasadaro izvo zvikafu hazvifanirwe kukurudzirwa. Chikafu chine akawanda anoshanda zvinongedzo - saka kana uchiongorora chikafu uye zvekuwedzera iwe unofanirwa kufunga nezve mabatiro ezvese zvinoshanda zvinongedzo zvakapetwa kwete zvega.

Somuenzaniso Pummelo ine zvinhu zvinoshanda Quercetin, Apigenin, Caffeine, Isoliquiritigenin, Formononetin. Uye Red Raspberry ine zvinoshanda zvinosanganisa Quercetin, Ellagic Acid, Isoliquiritigenin, Formononetin, Curcumin uye pamwe nevamwe.

Chikanganiso chinowanzoitwa pakusarudza nekusarudza chikafu chekudya cheNhetembo Syndrome - kuongorora chete zvakasarudzwa zvinoshandiswa zviri muzvokudya uye kufuratira zvimwe. Nekuti zvakasiyana-siyana zvinoshanda zviri mukudya zvinogona kuva nemhedzisiro inopikisa kune vatyairi vegomarara - haugone cherry kutora zvinoshanda mukudya uye ma supplements ekuita sarudzo yekudya kune Nhetembo Syndrome.

HONGU – ZVOKUSARUDZA ZVOKUDYA ZVINOKOSHA NEGONSA. ZVISARUDZO ZVOKUDYA ZVINOFANIRA KUFUNGA ZVINHU ZVINHU ZVINHU ZVINOSHANDA PACHIDYA.

Hunyanzvi hunodiwa paKudya Kwekudya Kwemunhu kune Nhetembo Syndrome?

Kudya kwakasarudzika kwegomarara senge Nhetembo Syndrome ine zvinokurudzirwa zvekudya / zvinowedzera; zvisingakurudzirwe chikafu / ma supplements ane semuenzaniso mabikirwo anotungamira kushandiswa kwezvikafu zvinokurudzirwa. Muenzaniso wekudya kwakasiyana-siyana unogona kuonekwa pane izvi batanidzo.

Kufunga kuti ndezvipi zvekudya zvinokurudzirwa kana kwete zvakaomesesa, zvinoda hunyanzvi muNhetembo Syndrome biology, sainzi yechikafu, genetics, biochemistry pamwe nekunzwisisa kwakanaka kwemashandiro anoita marapirwo egomarara uye kusagadzikana kwakabatana uko kurapwa kwaigona kumira kushanda.

ZVINONYANYA ZVINONYANYA ZVINODIWA KUTI ZVINOVAKA ZVINOVAKA MUNHU ZVINHU ZVINHU ZVINOITA: CANCER BIOLOGY, FOOD SCIENCE, KURAPA MAKANZA UYE GENETICS.

Hunhu hwegomarara seNhetembo Syndrome

Magomarara ese akaita seNhetembo Syndrome anogona kuratidzirwa neyakasiyana seti ye biochemical nzira - masiginecha nzira dzeNhetembo Syndrome. Nzira dzeBiochemical dzakadai seExtracellular Matrix Remodelling, Cytokine Signaling, PI3K-AKT-MTOR Signaling, MAPK Signaling chikamu chetsanangudzo yeSiginecha yeNhetembo Syndrome. Kenza yemunhu wega genetics inogona kuve yakasiyana uye nekudaro siginicha yavo yegomarara inogona kuve yakasarudzika.

Kurapa kunoshanda kweNhetembo Syndrome kunofanirwa kuziva nzira dzakasaina dzebiochemical yemurwere wega wega wegomarara uye munhu ari panjodzi yemajini. Saka marapirwo akasiyana ane maitiro akasiyana ezviito anoshanda kune varwere vakasiyana. Saizvozvo uye nekuda kwezvikonzero zvakafanana zvekudya uye zvekuwedzera zvinoda kuitirwa munhu wega wega. Saka zvimwe zvekudya uye zvekuwedzera zvinokurudzirwa kuNhetembo Syndrome kana uchitora kurapwa kenza Melphalan, uye zvimwe zvekudya uye zvekuwedzera hazvikurudzirwe.

Sources like cBioPortal uye vamwe vazhinji vanopa mumiriri wehuwandu hwevarwere data risingazivikanwe kubva kukiriniki miedzo yezvese zviratidzo zvegomarara. Iyi dhata ine yekiriniki yekuongorora yeruzivo senge sampuli saizi / nhamba yevarwere, mapoka ezera, murume kana mukadzi, dzinza, marapirwo, bundu saiti uye chero genetic mutations.

LATS2, CYSLTR2, IRS2, CUL4A neERCC5 ndiwo mazita emhando yepamusoro akashumwa mazita eNhetembo Syndrome. LATS2 inoshumwa mu50.41176471% yevanomiririra varwere mukati meyese miedzo yekiriniki. Uye CYSLTR2 inonzi mu50.41176471%. Iyo yakasanganiswa yehuwandu hwevarwere data inovhara mazera kubva kusvika . % yedata revarwere vanoonekwa sevarume. Iyo Nhetembo Syndrome biology pamwe neyakashumwa genetics pamwe chete inotsanangura huwandu hwehuwandu hunomiririrwa siginecha biochemical nzira dzegomarara iri. Kana iyo yega cancer bundu genetics kana majini anokonzera njodzi achizivikanwa zvakare saka izvo zvinofanirwa kushandiswawo kune chikafu chemunhu.

ZVAKASARUDZA KUDYA ZVINODYA ZVINOFANIRA KUFANIRA NEMUNHU WEMUNHU WEMUNHU WEMUNHU WEGONSI.

Zvokudya neZviwedzerwa zveNhetembo Syndrome

Kune Varwere veCancer

Varwere vegomarara vari pakurapa kana pakuchengeta palliative vanofanira kuita sarudzo pazvekudya uye zvekuwedzera - zvemacalorie anodiwa ekudya, kubata chero mhedzisiro yekurapa uyezve nekugadzirisa kenza. Zvese zvinodyarwa-zvikafu hazvina kuenzana uye kusarudza uye kuisa pamberi pezvikafu zvakagadzirirwa munhu uye zvakagadzirirwa kuenderera mberi kurapwa kwegomarara kwakakosha uye kwakaoma. Heano mimwe mienzaniso inopa nhungamiro yekuita sarudzo dzekudya.

Sarudza Vegetable WAX ​​GOURD kana GREEN BELL PEPPER?

Vegetable Wax Gourd ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seMyricetin, Apigenin, Isoliquiritigenin, Formononetin, Curcumin. Izvi zvinoshandiswa zvinosanganisa zvinoshandisa nzira dzakasiyana dzebiochemical seJAK-STAT Signaling, MAPK Signaling, NFKB Signaling uye MYC Signaling nevamwe. Wax Gourd inokurudzirwa kuNhetembo Syndrome apo chirwere chegomarara chiri kuenderera mberi chiri Melphalan. Izvi zvinodaro nekuti Wax Gourd inogadziridza idzo nzira dzebiochemical dzakataurwa nesainzi kuti dzigonese mashandiro eMelplan.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuriwo Green Bell Pepper ndeyeMyricetin, Quercetin, Isoliquiritigenin, Resveratrol, Formononetin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical senge DNA Kugadzirisa, Cytokine Signaling uye PI3K-AKT-MTOR Kuratidzira uye vamwe. Green Bell Pepper haikurudzirwe kune Nhetembo Syndrome kana ichiramba ichirapwa kenza iri Melphalan nekuti inogadzirisa idzo biochemical nzira dzinoita kuti kurapwa kwegomarara kurambe kana kusadaira.

MUDONDO WEWAX WEMURIWO INOKURUDZWA PAMUSORO PAMUSORO PEREEN BELL MPIPI YENhetembo Syndrome NEKURAPA Melphalan.

Sarudza Muchero RED RASPBERRY kana PUMMELO?

Chibereko Chitsvuku Raspberry chine zvakawanda zvinoshanda zvinosanganisa kana bioactives seQuercetin, Ellagic Acid, Isoliquiritigenin, Formononetin, Curcumin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical seDNA Kugadzirisa, Hypoxia, MAPK Kuratidzira uye Oxidative Stress nevamwe. Red Raspberry inokurudzirwa kune Nhetembo Syndrome apo inoenderera mberi kurapwa kwegomarara iri Melphalan. Izvi zvinodaro nekuti Red Raspberry inogadzirisa idzo biochemical nzira dzakataurwa nesainzi kuti dzikurudzire maitiro eMelphalan.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuchero Pummelo ndeye Quercetin, Apigenin, Caffeine, Isoliquiritigenin, Formononetin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical seDNA Repair uye Oxidative Stress nevamwe. Pummelo haina kukurudzirwa kuNhetembo Syndrome kana ichienderera mberi kurapwa kwegomarara iri Melphalan nekuti inogadzirisa idzo biochemical nzira dzinoita kuti kurapwa kwegomarara kurambe kana kusadaira.

MUCHERO RED RASPBERRY INOKURUDZWA PAMUSORO PAMUSORO PAMUSORO PAMUSORO PEPUMMELO YENhetembo Syndrome NEKURAPA Melphalan.

Sarudza Nut HAZELNUT kana BRAZIL NUT?

Hazelnut ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seMyricetin, Apigenin, Isoliquiritigenin, Formononetin, Curcumin. Izvi zvinoshandiswa zvinosanganisa zvinoshandisa nzira dzakasiyana dzebiochemical seJAK-STAT Signaling, Hypoxia, MAPK Signaling uye MYC Signaling nevamwe. Hazelnut inokurudzirwa kuNhetembo Syndrome kana ichienderera mberi kurapwa kwegomarara iri Melphalan. Izvi zvinodaro nekuti Hazelnut inogadzirisa idzo nzira dzebiochemical dzakataurwa nesainzi kuti dzikurudzire kuita kweMelphalan.

Zvimwe zvezvinhu zvinoshanda kana bioactives muBrazil Nut ndeye Ellagic Acid, Isoliquiritigenin, Formononetin, Curcumin, Phloretin. Izvi zvinoshanda zvinosanganisa zvinoshandisa nzira dzakasiyana dzebiochemical seDNA Kugadzirisa, MAPK Kusaina uye MYC Kuratidzira uye vamwe. Brazil Nut haikurudzirwe kune Nhetembo Syndrome kana ichienderera mberi kurapwa kwegomarara iri Melphalan nekuti inogadzirisa idzo biochemical nzira dzinoita kuti kurapwa kwegomarara kurambe kana kusadaira.

HAZELNUT INOKURUDZWA PAMUSORO PAMUSORO PEBRAZIL NUT YENhetembo Syndrome NEKURAPA Melphalan.

Kune Vanhu Vane Genetic Risk yeCancer

Mubvunzo wakabvunzwa nevanhu vane genetic risk yeNhetembo Syndrome kana nhoroondo yemhuri ndeye "Chii Chandinofanira Kudya Zvakasiyana Kubva Kare?" uye masarudzire avanofanira kuita zvekudya uye zvekuwedzera kuti vatarise njodzi dzechirwere. Sezvo kune njodzi yegomarara hapana chinogoneka maererano nekurapa - sarudzo dzezvekudya uye zvekuwedzera zvinove zvakakosha uye chimwe chezvinhu zvishoma zvingaite zvinogona kuitwa. Zvese zvinodyarwa-zvikafu hazvina kuenzana uye zvichibva pane zvakazivikanwa genetics uye nzira siginecha - sarudzo dzechikafu nekuwedzera dzinofanirwa kuve munhu.

Sarudza Vegetable GIANT BUTTERBUR kana MUSTARD SPINACH?

Vegetable Giant Butterbur ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seApigenin, Kaempferol, Myricetin, Isoliquiritigenin, Curcumin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seDNA Kugadzirisa, P53 Signaling, Angiogenesis uye MYC Signaling nevamwe. Giant Butterbur inokurudzirwa kune njodzi yeNhetembo Syndrome kana yakabatana genetic njodzi iri CUL4A. Izvi zvinodaro nekuti Giant Butterbur inowedzera idzo biochemical nzira dzinopokana nemadhiraivha emasaini ayo.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuriwo Mustard Sipinachi ndeye Apigenin, Kaempferol, Myricetin, Isoliquiritigenin, Curcumin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical senge DNA Kugadzirisa uye Cell Cycle Checkpoints nevamwe. Mustard Sipinachi haikurudzirwe kana njodzi yeNhetembo Syndrome kana yakabatana genetic njodzi iri CUL4A nekuti inowedzera siginecha nzira dzayo.

VEGETABLE GIANT BUTTERBUR INORUDZIRWA PAMUSORO PEMUSTARD SPINACH YECUL4A GENETIC RISK YECANCER.

Sarudza Chibereko NANCE kana FIG?

Chibereko Nance chine zvakawanda zvinoshanda zvinosanganisa kana bioactives seApigenin, Kaempferol, Myricetin, Isoliquiritigenin, Curcumin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical senge Hypoxia, P53 Signaling uye Angiogenesis nevamwe. Nance inokurudzirwa kune njodzi yeNhetembo Syndrome kana yakabatana genetic njodzi iri CUL4A. Izvi zvinodaro nekuti Nance inowedzera idzo biochemical nzira dzinopokana nemadhiraivha emasaini ayo.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuchero Fig ndeye Quercetin, Kaempferol, Isoliquiritigenin, Curcumin, Catechol. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical senge MAPK Kusaina, DNA Kugadzirisa uye PI3K-AKT-MTOR Kuratidzira uye vamwe. Fig haikurudzirwe kana njodzi yeNhetembo Syndrome kana yakabatana genetic njodzi iri CUL4A nekuti inowedzera siginecha nzira dzayo.

FRUIT NANCE INOKURUDZWA PAMUSORO PAMUSORO PECUL4A GENETIC RISK YECANCER.

Sarudza Nut BUTTERNUT kana EUROPEAN CHESTNUT?

Butternut ine zvakawanda zvinoshanda zvinosanganisa kana bioactives zvakaita seApigenin, Kaempferol, Myricetin, Isoliquiritigenin, Curcumin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical seDNA Kugadzirisa, Hypoxia, P53 Signaling uye MAPK Signaling nevamwe. Butternut inokurudzirwa kune njodzi yeNhetembo Syndrome kana yakabatana genetic ngozi iri CUL4A. Izvi zvinodaro nekuti Butternut inowedzera idzo nzira dzebiochemical dzinopesana nemadhiraivha ayo.

Zvimwe zvezvinoshandiswa zvinoshandiswa kana bioactives muEurope Chestnut ndeye Apigenin, Quercetin, Kaempferol, Myricetin, Isoliquiritigenin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical seDNA Kugadzirisa uye vamwe. European Chestnut haikurudzirwe kana njodzi yeNhetembo Syndrome kana yakabatana genetic njodzi iri CUL4A nekuti inowedzera siginecha nzira dzayo.

BUTTERNUT INOKURUKURWA PAMUSORO PAEUROPA CHESTNUT YECUL4A GENETIC RISK YECANCER.

Mhedziso

Zvokudya uye Zvekuwedzera zvakasarudzwa sarudzo dzakakosha kune vane gomarara seNhetembo Syndrome. Nhetembo Syndrome varwere uye vanhu vane genetic-njodzi vanogara vaine mubvunzo uyu: "Ndezvipi zvekudya uye zvinovaka muviri zvinokurudzirwa kwandiri uye izvo zvisiri?" Pane chitendero chakajairika chinova fungidziro isiriyo yekuti zvese zvinodyarwa-zvikafu zvinogona kubatsira kana kwete asi zvisingakuvadze. Zvimwe zvekudya uye zvekuwedzera zvinogona kukanganisa marapirwo egomarara kana kusimudzira mamorekuru enzira yegomarara.

Kune marudzi akasiyana ezviratidzo zvegomarara senge Nhetembo Syndrome, imwe neimwe iine tumor genetics ine mamwe ma genomic akasiyana kune mumwe nemumwe. Kuwedzera kurapwa kwegomarara uye chemotherapy ine yakasarudzika nzira yekuita. Chikafu chega chega seWax Gourd chine mabioactive akasiyana muhuwandu hwakasiyana, izvo zvine chekuita nenzira dzakasiyana uye dzakasiyana dzebiochemical nzira. Tsanangudzo yekudya yakasarudzika ndeyakasarudzika chikafu kurudziro yegomarara chiratidzo, marapirwo, genetics, mararamiro uye zvimwe zvinhu. Sarudzo dzehutano hwemunhu hwegomarara dzinoda ruzivo rwegomarara biology, sainzi yechikafu uye kunzwisisa kweakasiyana chemotherapy marapirwo. Chekupedzisira kana paine shanduko yekurapa kana nyowani genomics inoonekwa - iyo inovaka muviri inoda kuongororwazve.

Iyo addon nutrition personalization mhinduro inoita kuti sarudzo ive nyore uye inobvisa zvese zvekufungidzira mukupindura mubvunzo, "Ndezvipi zvekudya zvandinofanira kusarudza kana kusasarudzira Nhetembo Syndrome?". Iyo addon yakawanda-yekuranga timu inosanganisira varapi vegomarara, masayendisiti ekiriniki, mainjiniya esoftware uye masayendisiti edata.

References

• Daidzein mhedzisiro pahomoni refractory prostate cancer in vitro uye in vivo ichienzaniswa negenistein uye soy inobvisa: kugona kweradiotherapy.
• Iyo citrus flavonoid naringenin inokurudzira DNA kugadziriswa mumasero ekenza yeprostate.
• Kukonzeresa kwenguva pfupi receptor inogona vanilloid mhando 1 (TRPV1) ne capsaicin induces Fas/CD95-mediated apoptosis yemasero ekenza yeurothelial nenzira inoenderana neATM.
• Mhedzisiro ye isoliquiritigenin pamasero egomarara reovarian.
• https://rarediseases.org/rare-diseases/poems-syndrome
• https://www.mayoclinic.org/diseases-conditions/poems-syndrome/symptoms-causes/syc-20352678#:~:text=POEMS%20syndrome%20is%20a%20rare,your%20hands%20%E2%80%94%20and%20difficulty%20breathing.
• https://my.clevelandclinic.org/health/diseases/17985-poems-syndrome )