Zvokudya zveGomarara reMapapu risiri diki!

ziviso

Zvikafu zveAsiri-diki Cell Lung Cancer zvinofanirwa kuve zvakasarudzika kune wega wega uye zvakare zvinofanirwa kuchinjika kana kenza kurapwa kana bundu genetic shanduko. Iyo yemunhu uye kugadzirisa kunofanirwa kufunga nezvese zvinoshanda zvinosanganiswa kana bioactives zviri muzvokudya zvakasiyana zvine chekuita negomarara biology, genetics, marapirwo, mararamiro uye zvido zvekudya. Saka nepo chikafu chiri chimwe chezvisarudzo zvakakosha zvemurwere wegomarara uye munhu ari panjodzi yegomarara - kusarudza chikafu chekudya harisi basa riri nyore.

Kune Isiri-diki Cell Lung Cancer zvine basa here kuti munhu anodya miriwo, michero, nzungu, mhodzi ipi?

Mubvunzo wakajairika wekudya unobvunzwa nevarwere vegomarara uye vanhu vari pa-genetic njodzi yegomarara ndeye - kumakonza akaita seNon-small Cell Lung Cancer zvine basa here kuti ndechipi chikafu chandinodya uye chandisingade? Kana kuti ndikatevera kudya-kwekudyara kunokwana kenza seNon-small Cell Lung Cancer?

Semuenzaniso zvine basa here kana muriwo weCauliflower uchidyiwa zvakanyanya kana uchienzaniswa neRocket Salad (ssp.)? Zvinoita mutsauko here kana muchero Malus (gakanje Apple) rikasarurwa pane Black Mulberry? Zvakare kana sarudzo dzakafanana dzakaitirwa nzungu/mhodzi dzakaita seButternut pamusoro peEuropean Chestnut uye nemapuruzi akaita seGram Bean pamusoro peMung Bean. Uye kana izvo zvandinodya zvine basa - zvino munhu angaziva sei zvikafu zvinokurudzirwa kuNon-Diki Cell Lung Cancer uye ndiyo mhinduro imwechete kune wese ane chirwere chakafanana kana genetic njodzi?

Ehe! Zvokudya zvaunodya zvine chekuita neNon-small Cell Lung Cancer!

Mazano echikafu anogona kunge asina kufanana kune wese munhu uye anogona kuve akasiyana kunyangwe kune imwechete kuongororwa uye genetic njodzi.

Zvokudya zvose (miriwo, michero, nzungu, mhodzi, pulses, mafuta nezvimwewo) uye zvokudya zvinovaka muviri zvinoumbwa nezvinodarika imwe inoshanda mamolecular ingredient kana bio-actives muzvikamu zvakasiyana uye uwandu. Chinhu chimwe nechimwe chinoshanda chine nzira yakasarudzika yekuita - iyo inogona kuve activation kana inhibition yeakasiyana biochemical nzira. Zvikafu zvakangotaurwa uye zvekuwedzera izvo zvinokurudzirwa ndezviya zvisingakonzere kuwedzera kwemamorekuru anotyaira cancer asi anodzideredza. Zvikasadaro izvo zvikafu hazvifanirwe kukurudzirwa. Chikafu chine akawanda anoshanda zvinongedzo - saka kana uchiongorora chikafu uye zvekuwedzera iwe unofanirwa kufunga nezve mabatiro ezvese zvinoshanda zvinongedzo zvakapetwa kwete zvega.

Semuenzaniso Malus (crab Apple) ine zvinhu zvinoshanda Curcumin, Delphinidin, Lycopene, Isoliquiritigenin, Formononetin. Uye Black Mulberry ine zvinhu zvinoshanda Quercetin, Curcumin, Delphinidin, Isoliquiritigenin, Formononetin uye pamwe nevamwe.

Chikanganiso chinowanzoitwa pakusarudza nekusarudza chikafu chekudya cheNon-Diki Cell Lung Cancer - kuongorora chete zvakasarudzwa zvinoshandiswa zviri muzvokudya uye kufuratira zvimwe. Nekuti zvakasiyana-siyana zvinoshanda zviri mukudya zvinogona kuva nemhedzisiro inopikisa kune vatyairi vegomarara - haugone kutora cherry inoshanda mukudya uye ma supplements ekuita sarudzo yekudya kune Isiri-diki Cell Lung Cancer.

HONGU – ZVOKUSARUDZA ZVOKUDYA ZVINOKOSHA NEGONSA. ZVISARUDZO ZVOKUDYA ZVINOFANIRA KUFUNGA ZVINHU ZVINHU ZVINHU ZVINOSHANDA PACHIDYA.

Hunyanzvi Hunodiwa Kuti Kuve Nezvokudya Zvinovaka Munhu Kwegomarara Repamapapu Risiri diki?

Kudya kwakasarudzika kwegomarara senge Isiri diki Cell Lung Cancer ine zvinokurudzirwa zvekudya / zvinowedzera; zvisingakurudzirwe chikafu / ma supplements ane muenzaniso mabikirwo ayo anotungamira kushandiswa kwezvikafu zvinokurudzirwa. Muenzaniso wekudya kwakasiyana-siyana unogona kuonekwa pane izvi batanidzo.

Kufunga kuti ndezvipi zvekudya zvinokurudzirwa kana kwete zvakaomesesa, zvinoda hunyanzvi muIsiri diki Cell Lung Cancer biology, chikafu sainzi, genetics, biochemistry pamwe nekunzwisisa kwakanaka kwemashandiro anoita marapirwo egomarara uye kusagadzikana kwakabatana uko kurapwa kwaigona kumira kushanda.

ZVINONYANYA ZVINONYANYA ZVINODIWA KUTI ZVINOVAKA ZVINOVAKA MUNHU ZVINHU ZVINHU ZVINOITA: CANCER BIOLOGY, FOOD SCIENCE, KURAPA MAKANZA UYE GENETICS.

Hunhu hwegomarara seNon-small Cell Lung Cancer

Ese magomarara seAsiri diki Cell Lung Cancer anogona kuratidzwa neyakasiyana seti yebiochemical nzira - nzira dzekusaina dzeIsiri diki Cell Lung Cancer. Nzira dzeBiochemical dzakadai seRAS-RAF Chiratidzo, Apoptosis, Diki Molecule Transport, Extracellular Matrix Remodeling chikamu chetsanangudzo yeSiri-diki Cell Lung Cancer. Kenza yemunhu wega genetics inogona kuve yakasiyana uye nekudaro siginicha yavo yegomarara inogona kuve yakasarudzika.

Kurapa kunoshanda kune Isiri diki Cell Lung Cancer inofanirwa kuziva iyo inosanganisirwa siginecha yebiochemical nzira kune wega wega cancer murwere uye munhu ari panjodzi yemajini. Saka marapirwo akasiyana ane maitiro akasiyana ezviito anoshanda kune varwere vakasiyana. Saizvozvo uye nekuda kwezvikonzero zvakafanana zvekudya uye zvekuwedzera zvinoda kuitirwa munhu wega wega. Saka zvimwe zvekudya uye zvekuwedzera zvinokurudzirwa kune Isiri-diki Cell Lung Cancer kana uchitora kenza kurapwa Erlotinib, uye zvimwe zvekudya uye zvinowedzera hazvikurudzirwe.

Sources like cBioPortal uye vamwe vazhinji vanopa mumiriri wehuwandu hwevarwere data risingazivikanwe kubva kukiriniki miedzo yezvese zviratidzo zvegomarara. Iyi dhata ine yekiriniki yekuongorora yeruzivo senge sampuli saizi / nhamba yevarwere, mapoka ezera, murume kana mukadzi, dzinza, marapirwo, bundu saiti uye chero genetic mutations.

LRP2, CACNA1E, SI, TIAM1 uye COL6A3 ndiwo epamusoro-soro akataurwa majini eNon-Diki Cell Lung Cancer. LRP2 inoshumwa mu10.1% yevanomiririra varwere mukati meyese miedzo yekiriniki. Uye CACNA1E inoshumwa mu9.4%. Iyo yakasanganiswa yehuwandu hwevarwere data inovhara makore kubva pa37 kusvika 88. 49.4 % yedata remurwere inozivikanwa sevarume. Iyo Isiri diki Cell Lung Cancer biology pamwe neyakashumwa genetics pamwe chete inotsanangura huwandu hwehuwandu hunomiririrwa siginecha biochemical nzira dzegomarara iri. Kana iyo yega cancer tumor genetics kana majini anokonzera njodzi achizivikanwawo saka izvo zvinofanirwa kushandiswawo kune hutano hwemunhu.

ZVAKASARUDZA KUDYA ZVINODYA ZVINOFANIRA KUFANIRA NEMUNHU WEMUNHU WEMUNHU WEMUNHU WEGONSI.

Chikafu uye Zvekuwedzera kune Isiri diki Cell Lung Cancer

Kune Varwere veCancer

Varwere vegomarara vari pakurapa kana pakuchengeta palliative vanofanira kuita sarudzo pazvekudya uye zvekuwedzera - zvemacalorie anodiwa ekudya, kubata chero mhedzisiro yekurapa uyezve nekugadzirisa kenza. Zvese zvinodyarwa-zvikafu hazvina kuenzana uye kusarudza uye kuisa pamberi pezvikafu zvakagadzirirwa munhu uye zvakagadzirirwa kuenderera mberi kurapwa kwegomarara kwakakosha uye kwakaoma. Heano mimwe mienzaniso inopa nhungamiro yekuita sarudzo dzekudya.

Sarudza Vegetable CAULIFLOWER kana ROCKET SALAD (SSP.)?

Vegetable Cauliflower ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seCurcumin, Delphinidin, Isoliquiritigenin, Formononetin, Phloretin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seEpithelial kuenda kuMesenchymal Transition, P53 Signaling, WNT Beta Catenin Signaling uye MYC Signaling nevamwe. Koliflower inokurudzirwa kuNon-small Cell Lung Cancer kana chirwere chegomarara chiri kuramba chiri Erlotinib. Izvi zvinodaro nekuti Cauliflower inogadzirisa idzo nzira dzebiochemical dzakataurwa nesainzi kuti dzigonese mhedzisiro yeErlotinib.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuriwo Rocket Salad (ssp.) ndeye Quercetin, Curcumin, Delphinidin, Lycopene, Isoliquiritigenin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seTGFB Signaling uye PI3K-AKT-MTOR Signaling nevamwe. Rocket Salad (ssp.) haikurudzirwe kuNon-Diki Cell Lung Cancer kana ichienderera mberi kurapwa kwegomarara iri Erlotinib nekuti inogadzirisa idzo biochemical nzira dzinoita kuti kurapwa kwegomarara risarambe kana kusadaira.

VEGETABLE CAULIFLOWER INORUDZIRWA PAMUSORO PAMUSORO PEROCKET SALAD (SSP.) Kune Isiri diki Cell Lung Cancer UYE KURAPA Erlotinib.

Sarudza Muchero BLACK MULBERRY kana MALUS (CRAB APPLE)?

Fruit Black Mulberry ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seQuercetin, Curcumin, Delphinidin, Isoliquiritigenin, Formononetin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana-siyana dzebiochemical seEpithelial kuenda kuMesenchymal Transition, Extracellular Matrix Remodelling, Apoptosis uye MAPK Signaling nevamwe. Black Mulberry inokurudzirwa kuNon-small Cell Lung Cancer kana chirwere chegomarara chiri kuramba chiri Erlotinib. Izvi zvinodaro nekuti Black Mulberry inogadzirisa idzo nzira dzebiochemical dzakataurwa nesainzi kuti dzikurudzire maitiro eErlotinib.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuchero Malus (crab Apple) ndeye Curcumin, Delphinidin, Lycopene, Isoliquiritigenin, Formononetin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seTGFB Signaling uye PI3K-AKT-MTOR Signaling nevamwe. Malus (gakanje Apple) haikurudzirwe kune Isiri-diki Cell Lung Cancer kana ichienderera mberi kurapwa kwegomarara iri Erlotinib nekuti inogadzirisa idzo nzira dzebiochemical dzinoita kuti kurapwa kwegomarara kumire kana kusadaira.

MUCHERO MUTEMA MUMARU INOKURURWA PAMUSORO PAMALUS (CRAB APPLE) KUNE Isiri diki Cell Lung Cancer UYE KURAPA Erlotinib.

Sarudza Nut BUTTERNUT kana EUROPEAN CHESTNUT?

Butternut ine zvinhu zvakawanda zvinoshanda kana bioactives seCurcumin, Delphinidin, Lycopene, Isoliquiritigenin, Formononetin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seTGFB Signaling, P53 Signaling, MAPK Signaling uye MYC Signaling nevamwe. Butternut inokurudzirwa kuNon-small Cell Lung Cancer kana chirwere chegomarara chiri kuramba chiri Erlotinib. Izvi zvinodaro nekuti Butternut inogadzirisa idzo nzira dzebiochemical dzakataurwa nesainzi kuti dzikurudzire maitiro eErlotinib.

Zvimwe zvezvinhu zvinoshanda kana bioactives muEuropean Chestnut ndeye Quercetin, Ellagic Acid, Curcumin, Delphinidin, Isoliquiritigenin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seTGFB Signaling, Epithelial kune Mesenchymal Transition uye WNT Beta Catenin Signaling nevamwe. European Chestnut haikurudzirwe kune Isiri diki Cell Lung Cancer kana ichienderera mberi kurapwa kwegomarara iri Erlotinib nekuti inogadzirisa idzo biochemical nzira dzinoita kuti kurapwa kwegomarara kumire kana kusadaira.

BUTTERNUT INOKURUKURIRWA PAMUSORO PEEUROPA CHESTNUT KUNE Isiri diki Cell Lung Gomarara UYE KURAPA Erlotinib.

Kune Vanhu Vane Genetic Risk yeCancer

Mubvunzo wakabvunzwa nevanhu vane genetic risk yeIsiri diki Cell Lung Cancer kana nhoroondo yemhuri ndeye "Chii Chandinofanira Kudya Zvakasiyana Kubva Kare?" uye masarudzire avanofanira kuita zvekudya uye zvekuwedzera kuti vatarise njodzi dzechirwere. Sezvo kune njodzi yegomarara hapana chinogoneka maererano nekurapa - sarudzo dzezvekudya uye zvekuwedzera zvinove zvakakosha uye chimwe chezvinhu zvishoma zvingaite zvinogona kuitwa. Zvese zvinodyarwa-zvikafu hazvina kuenzana uye zvichibva pane zvakazivikanwa genetics uye nzira siginecha - sarudzo dzechikafu nekuwedzera dzinofanirwa kuve munhu.

Sarudza Vegetable GIANT BUTTERBUR kana OYSTER MUSHROOM?

Vegetable Giant Butterbur ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seApigenin, Curcumin, Lupeol, Formononetin, Daidzein. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seAdherens junction, P53 Signaling, Cell Junctions uye RAS-RAF Signaling nevamwe. Giant Butterbur inokurudzirwa panjodzi yeNon-Diki Cell Lung Cancer kana njodzi yemajini yakabatana iri CACNA1E. Izvi zvinodaro nekuti Giant Butterbur inowedzera idzo biochemical nzira dzinopokana nemadhiraivha emasaini ayo.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuriwo Oyster Mushroom ndeye Apigenin, Curcumin, Lupeol, Formononetin, Daidzein. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seDiki Molecule Yekutakura uye PI3K-AKT-MTOR Kuratidzira uye vamwe. Oyster Mushroom haakurudzirwe kana njodzi yeIsiri diki Cell Lung Cancer kana yakabatana genetic njodzi iri CACNA1E nekuti inowedzera siginecha nzira dzayo.

MURIWO MURUME BUTTERBUR ANOKURUKURWA PAMUSORO PEOYSTER MUSHROOM YECACNA1E GENETIC RISK YECANCER.

Sarudza Chibereko CLOUDBERRY kana PUMMELO?

Chibereko Cloudberry chine zvakawanda zvinoshanda zvinosanganisa kana bioactives seApigenin, Curcumin, Quercetin, Ellagic Acid, Lupeol. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical seAdherens junction, P53 Signaling uye PI3K-AKT-MTOR Signaling nevamwe. Cloudberry inokurudzirwa panjodzi yeNon-small Cell Lung Cancer kana genetic risk iri CACNA1E. Izvi zvinodaro nekuti Cloudberry inowedzera idzo biochemical nzira dzinopokana nemadhiraivha emasaini ayo.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuchero Pummelo ndeye Apigenin, Curcumin, Quercetin, Lupeol, Formononetin. Izvi zvinoshandiswa zvinoshandiswa zvinoshandisa nzira dzakasiyana-siyana dzebiochemical dzakadai seExtracellular Matrix Remodelling, Diki Molecule Transport, Cytoskeletal Dynamics uye Cell Junctions nezvimwe. Pummelo haikurudzirwe kana njodzi yeIsiri-diki Cell Lung Cancer kana yakabatana genetic njodzi iri CACNA1E nekuti inowedzera siginecha nzira dzayo.

FRUIT CLOUDBERRY INOKURUKURWA PAMUSORO PEPUMMELO YECACNA1E GENETIC RISK YECANCER.

Sarudza Nut CHIA kana PISTACHIO?

Chia ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seApigenin, Curcumin, Lupeol, Formononetin, Daidzein. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical senge P53 Signaling, Focal Adhesion, Cell Junctions uye Diki Molecule Yekufambisa uye nevamwe. Chia inokurudzirwa panjodzi yeNon-small Cell Lung Cancer kana njodzi yemajini yakabatana iri CACNA1E. Izvi zvinodaro nekuti Chia inowedzera idzo nzira dzebiochemical dzinopesana nemadhiraivha ayo.

Zvimwe zvezvinhu zvinoshanda kana bioactives muPistachio ndeye Curcumin, Quercetin, Lupeol, Formononetin, Daidzein. Izvi zvinoshandiswa zvinoshandiswa zvinoshandisa nzira dzakasiyana dzebiochemical seFocal Adhesion, Cytoskeletal Dynamics uye Cell Junctions nevamwe. Pistachio haikurudzirwe kana njodzi yeIsiri diki Cell Lung Cancer kana yakabatana genetic njodzi iri CACNA1E nekuti inowedzera siginecha nzira dzayo.

CHIA INOKURUKURWA PASI PISTACHIO YECACNA1E GENETIC RISK YECANCER.

Mhedziso

Zvokudya uye Zvekuwedzera zvakasarudzwa sarudzo dzakakosha kune cancer seNon-diki Cell Lung Cancer. Vasiri diki Cell Lung Cancer varwere uye vanhu vane genetic-njodzi vanogara vaine mubvunzo uyu: "Ndezvipi zvekudya uye zvinovaka muviri zvinokurudzirwa kwandiri uye izvo zvisiri?" Pane chitendero chakajairika chinova fungidziro isiriyo yekuti zvese zvinodyarwa-zvikafu zvinogona kubatsira kana kwete asi zvisingakuvadze. Zvimwe zvekudya uye zvekuwedzera zvinogona kukanganisa marapirwo egomarara kana kukurudzira mamorekuru enzira yegomarara.

Kune marudzi akasiyana ezviratidzo zvegomarara senge Isiri diki Cell Lung Cancer, imwe neimwe iine akasiyana bundu genetics ine mamwe genomic misiyano pamunhu wega wega. Kuwedzera kurapwa kwegomarara uye chemotherapy ine yakasarudzika nzira yekuita. Chikafu chega chega seCauliflower chine mabioactive akasiyana muhuwandu hwakasiyana, izvo zvine chekuita neakasiyana uye akasiyana seti yebiochemical nzira. Tsanangudzo yekudya yakasarudzika ndeyakasarudzika chikafu kurudziro yegomarara chiratidzo, marapirwo, genetics, mararamiro uye zvimwe zvinhu. Sarudzo dzehutano hwemunhu hwegomarara dzinoda ruzivo rwegomarara biology, sainzi yechikafu uye kunzwisisa kweakasiyana chemotherapy marapirwo. Chekupedzisira kana paine shanduko yekurapa kana nyowani genomics inoonekwa - iyo inovaka muviri inoda kuongororwazve.

Iyo addon nutrition personalization solution inoita kuti sarudzo ive nyore uye inobvisa fungidziro yese mukupindura mubvunzo, "Ndezvipi zvekudya zvandinofanira kusarudza kana kusasarudzira Isiri-diki Cell Lung Cancer?". Iyo addon yakawanda-yekuranga timu inosanganisira varapi vegomarara, masayendisiti ekiriniki, mainjiniya esoftware uye masayendisiti edata.

References

• Pan Yakatangwa 2020
• Molecular Determinants of Response to Anti-Programmed Cell Death (PD) -1 uye Anti-Programmed Death-Ligand 1 (PD-L1) Blockade muVarwere Vasina-Diki-Sero-Sero Kenza Yemapapu Profiled With Targeted Next-Generation Sequencing.
• Morusin inokonzera kufa kwesero kuburikidza nekuita kusaina STAT3 mumaseru ekenza yeprostate.
• Vitamin C inowedzera epigenetic modifications inokonzerwa ne5-azacytidine uye cell cycle kusungwa muhepatocellular carcinoma cell lines HLE uye Huh7.
• Brassinin Inodzoreredza Inopindira Inogona YeLung Carcinoma Masero kuburikidza neDeactivation yePI3K/Akt/mTOR Signaling Cascade.
• β-Sitosterol uye Gemcitabine Exhibit Synergistic Anti-pancreatic Cancer Activity neModulating Apoptosis uye Inhibiting Epithelial-Mesenchymal Transition by Deactivating Akt / GSK-3β Signaling.
• Antiproliferative mhedzisiro yep-Coumaric acid inotarisa UPR activation nekudzikisira Grp78 mucolon cancer.