Zvokudya zveAmpullary Carcinoma?

ziviso

Zvikafu zveAmpullary Carcinoma zvinofanirwa kuve zvakasarudzika kune wega wega uye zvakare zvinofanirwa kuchinjika kana kenza kurapwa kana bundu genetic shanduko. Iyo yemunhu uye kugadzirisa kunofanirwa kufunga nezvese zvinoshanda zvinosanganiswa kana bioactives zviri muzvokudya zvakasiyana zvine chekuita negomarara biology, genetics, marapirwo, mararamiro uye zvido zvekudya. Saka nepo chikafu chiri chimwe chezvisarudzo zvakakosha zvemurwere wegomarara uye munhu ari panjodzi yegomarara - kusarudza chikafu chekudya harisi basa riri nyore.

Ampullary carcinoma, chirwere chisingawanzoitiki chinoitika panosangana bile duct uye pancreatic duct, yakasiyana mukuratidzwa kwayo uye kufungidzira. Iyo ICD-10 classification yeampullary carcinoma aids mune yayo yakajairwa kushuma uye kurapwa kwekutevera. Pathology rondedzero yegomarara iri yakakosha pakuongororwa, kazhinji inoratidzira yakasarudzika histological maficha. Staging, iyo inogona kutsanangurwa kuburikidza neradiology, kusanganisira CT scans, yakakosha pakuongorora kukura kwebundu uye kuronga kurapwa, nekuita radiology ichiita basa rakakosha. Chiyero chekupona uye kufungidzira kweampullary carcinoma inosiyana, zvichienderana nedanho rekuongororwa uye kupindura kurapwa. Zviratidzo zvakajairika zvinosanganisira jaundice, kurwadziwa mudumbu, uye kurasikirwa nehuremu. Kurapa kunowanzo sanganisira kuvhiya kuvhiyiwa, kungangoteverwa neadjuvant chemotherapy, kunyanya kana bundu racho rakura kana paine njodzi huru yekudzokazve. Iyo CAP (College of American Pathologists) protocol inopa nhungamiro yekuongororwa kwepathological yeampullary carcinoma. Kuenzanisa necholangiocarcinoma, imwe kenza yebiliary turakiti, yakakosha pakuongororwa kwakarurama, sezvo nzira yekurapa uye kufungidzira kunogona kusiyana zvakanyanya pakati pemamiriro maviri aya. Pakazara, kutungamirirwa kweampullary carcinoma kunoda nzira yakazara uye yakasiyana-siyana, kubatanidza nzira dzekuvhiya uye chemotherapeutic yekuvandudza migumisiro yevarwere.

Kune Ampullary Carcinoma zvine basa here kuti miriwo, michero, nzungu, mhodzi munhu anodya chii?

Mubvunzo wakajairika wekudya unobvunzwa nevarwere vegomarara uye vanhu vari pa-genetic njodzi yegomarara ndeye - kumakonza akaita seAmpullary Carcinoma zvine basa here kuti ndechipi chikafu chandinodya uye chandisingade? Kana kuti ndikatevera kudya-kwekudyara kunokwana kenza seAmpullary Carcinoma?

Semuenzaniso zvine basa here kana muriwo Giant Butterbur uchidyiwa zvakanyanya uchienzaniswa neSweden? Zvinoita mutsauko here kana muchero Pummelo uchifarirwa pane Red Raspberry? Zvakare kana sarudzo dzakafanana dzakaitirwa nzungu/mhodzi dzakaita seButternut pamusoro peEuropean Chestnut uye yemapurusi akaita seBroad Bean pamusoro peSoy Bean. Uye kana izvo zvandinodya zvine basa - zvino munhu angaziva sei zvikafu zvinokurudzirwa kuAmpullary Carcinoma uye ndiyo mhinduro imwechete kune wese ane chirwere chakafanana kana genetic njodzi?

Ehe! Zvokudya zvaunodya zvine chekuita neAmpullary Carcinoma!

Mazano echikafu anogona kunge asina kufanana kune wese munhu uye anogona kuve akasiyana kunyangwe kune imwechete kuongororwa uye genetic njodzi.

Zvokudya zvose (miriwo, michero, nzungu, mhodzi, pulses, mafuta nezvimwewo) uye zvokudya zvinovaka muviri zvinoumbwa nezvinodarika imwe inoshanda mamolecular ingredient kana bio-actives muzvikamu zvakasiyana uye uwandu. Chinhu chimwe nechimwe chinoshanda chine nzira yakasarudzika yekuita - iyo inogona kuve activation kana inhibition yeakasiyana biochemical nzira. Zvikafu zvakangotaurwa uye zvekuwedzera izvo zvinokurudzirwa ndezviya zvisingakonzere kuwedzera kwemamorekuru anotyaira cancer asi anodzideredza. Zvikasadaro izvo zvikafu hazvifanirwe kukurudzirwa. Chikafu chine akawanda anoshanda zvinongedzo - saka kana uchiongorora chikafu uye zvekuwedzera iwe unofanirwa kufunga nezve mabatiro ezvese zvinoshanda zvinongedzo zvakapetwa kwete zvega.

Somuenzaniso Pummelo ine zvinhu zvinoshanda Quercetin, Curcumin, Phloretin, Naringenin, Naringin. Uye Red Raspberry ine zvinoshanda zvinosanganisa Quercetin, Ellagic Acid, Curcumin, Phloretin, Formononetin uye pamwe nevamwe.

Chikanganiso chinowanzoitwa pakusarudza nekusarudza chikafu chekudya cheAmpullary Carcinoma - kuongorora chete zvakasarudzwa zvinoshandiswa zviri mukudya uye kufuratira zvimwe. Nekuti zvakasiyana-siyana zvinoshanda zviri mukudya zvinogona kuva nemhedzisiro inopikisa kune vatyairi vegomarara - haugone cherry kutora zvinoshanda muzvikafu uye zvinowedzera kuita sarudzo yekudya kune Ampullary Carcinoma.

HONGU – ZVOKUSARUDZA ZVOKUDYA ZVINOKOSHA NEGONSA. ZVISARUDZO ZVOKUDYA ZVINOFANIRA KUFUNGA ZVINHU ZVINHU ZVINHU ZVINOSHANDA PACHIDYA.

Unyanzvi hunodiwa paKudya Kwekudya Kwemunhu kune Ampullary Carcinoma?

Kudya kwakasarudzika kwegomarara senge Ampullary Carcinoma ine zvinokurudzirwa zvekudya / zvinowedzera; zvisingakurudzirwe chikafu / ma supplements ane semuenzaniso mabikirwo anotungamira kushandiswa kwezvikafu zvinokurudzirwa. Muenzaniso wekudya kwakasiyana-siyana unogona kuonekwa pane izvi batanidzo.

Kufunga kuti ndezvipi zvekudya zvinokurudzirwa kana kwete zvakaomesesa, zvinoda hunyanzvi muAmpullary Carcinoma biology, sainzi yechikafu, genetics, biochemistry pamwe nekunzwisisa kwakanaka kwemashandiro anoita marapirwo egomarara uye kusagadzikana kwakabatana uko kurapwa kwaigona kumira kushanda.

ZVINONYANYA ZVINONYANYA ZVINODIWA KUTI ZVINOVAKA ZVINOVAKA MUNHU ZVINHU ZVINHU ZVINOITA: CANCER BIOLOGY, FOOD SCIENCE, KURAPA MAKANZA UYE GENETICS.

Hunhu hwegomarara senge Ampullary Carcinoma

Ese magomarara seAmpullary Carcinoma anogona kuratidzirwa neyakasiyana seti yebiochemical nzira - iyo siginecha nzira dzeAmpullary Carcinoma. Biochemical pathways seNucleotide metabolism, Amino Acid Metabolism, PI3K-AKT-MTOR Signaling, MAPK Signaling chikamu chetsanangudzo yeAmpullary Carcinoma. Kenza yemunhu wega genetics inogona kuve yakasiyana uye nekudaro siginicha yavo yegomarara inogona kuve yakasarudzika.

Kurapa kunoshanda kweAmpullary Carcinoma kunoda kuziva nzira dzakasaina dzebiochemical kune mumwe nemumwe murwere wegomarara uye munhu ari panjodzi yemajini. Saka marapirwo akasiyana ane maitiro akasiyana ezviito anoshanda kune varwere vakasiyana. Saizvozvo uye nekuda kwezvikonzero zvakafanana zvekudya uye zvekuwedzera zvinoda kuitirwa munhu wega wega. Saka zvimwe zvekudya uye zvekuwedzera zvinokurudzirwa kuAmpullary Carcinoma kana uchitora kurapwa kenza Gemcitabine, uye zvimwe zvekudya uye zvekuwedzera hazvikurudzirwe.

Sources like cBioPortal uye vamwe vazhinji vanopa mumiriri wehuwandu hwevarwere data risingazivikanwe kubva kukiriniki miedzo yezvese zviratidzo zvegomarara. Iyi dhata ine yekiriniki yekuongorora yeruzivo senge sampuli saizi / nhamba yevarwere, mapoka ezera, murume kana mukadzi, dzinza, marapirwo, bundu saiti uye chero genetic mutations.

TP53, KRAS, APC, SMAD4 uye PIK3CA ndiwo mazita epamusoro akashumwa majini eAmpullary Carcinoma. TP53 inoshumwa mu56.2% yevanomiririra varwere mukati meyese miedzo yekiriniki. Uye KRAS inoshumwa mu48.9%. Kubatanidzwa kwehuwandu hwevarwere data inovhara mazera kubva pa32 kusvika 87. 62.3 % yedata remurwere inozivikanwa sevarume. Iyo Ampullary Carcinoma biology pamwe neyakashumwa genetics pamwe chete inotsanangura huwandu hwevanhu vanomiririrwa siginecha biochemical nzira dzegomarara iri. Kana iyo yega cancer bundu genetics kana majini anokonzera njodzi achizivikanwa zvakare saka izvo zvinofanirwa kushandiswawo kune chikafu chemunhu.

ZVAKASARUDZA KUDYA ZVINODYA ZVINOFANIRA KUFANIRA NEMUNHU WEMUNHU WEMUNHU WEMUNHU WEGONSI.

Chikafu uye Zvekuwedzera zveAmpullary Carcinoma

Kune Varwere veCancer

Varwere vegomarara vari pakurapa kana pakuchengeta palliative vanofanira kuita sarudzo pazvekudya uye zvekuwedzera - zvemacalorie anodiwa ekudya, kubata chero mhedzisiro yekurapa uyezve nekugadzirisa kenza. Zvese zvinodyarwa-zvikafu hazvina kuenzana uye kusarudza uye kuisa pamberi pezvikafu zvakagadzirirwa munhu uye zvakagadzirirwa kuenderera mberi kurapwa kwegomarara kwakakosha uye kwakaoma. Heano mimwe mienzaniso inopa nhungamiro yekuita sarudzo dzekudya.

Sarudza Vegetable GIANT BUTTERBUR kana SWEDE?

Vegetable Giant Butterbur ine zvakawanda zvinoshanda zvinosanganisa kana bioactives zvakaita seCurcumin, Myricetin, Phloretin, Formononetin, Lycopene. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seMetastasis, PI3K-AKT-MTOR Signaling, NFKB Signaling uye Epithelial kune Mesenchymal Transition nevamwe. Giant Butterbur inokurudzirwa kuAmpullary Carcinoma apo chirwere chegomarara chiri kuramba chiri Gemcitabine. Izvi zvinodaro nekuti Giant Butterbur inogadzirisa idzo nzira dzebiochemical dzakataurwa nesainzi kuti dzikurudzire maitiro eGemcitabine.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuriwo weSwede ndeye Curcumin, Phloretin, Formononetin, Lupeol, Caffeic Acid. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical senge Oxidative Stress, TGFB Signaling uye Endoplasmic Reticulum Stress nevamwe. Swede haikurudzirwe kuAmpullary Carcinoma kana ichiramba ichirapwa kenza iri Gemcitabine nekuti inogadzirisa idzo nzira dzebiochemical dzinoita kuti kurapwa kwegomarara kurambe kana kusadaira.

VEGETABLE GIANT BUTTERBUR INORUMBIRWA PAMUSORO PASWEDE YEAmpullary Carcinoma UYE KURAPA Gemcitabine.

Sarudza Muchero RED RASPBERRY kana PUMMELO?

Chibereko Chitsvuku Raspberry chine zvakawanda zvinoshanda zvinosanganisa kana bioactives seQuercetin, Ellagic Acid, Curcumin, Phloretin, Formononetin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seMetastasis, PI3K-AKT-MTOR Signaling, NFKB Signaling uye Epithelial kune Mesenchymal Transition nevamwe. Red Raspberry inokurudzirwa kuAmpullary Carcinoma apo chirwere chegomarara chiri kuramba chiri Gemcitabine. Izvi zvinodaro nekuti Red Raspberry inogadzirisa idzo biochemical nzira dzakataurwa nesainzi kuti dzikurudzire mhedzisiro yeGemcitabine.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuchero Pummelo ndeye Quercetin, Curcumin, Phloretin, Naringenin, Naringin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seOxidative Stress uye Endoplasmic Reticulum Stress nevamwe. Pummelo haikurudzirwe kuAmpullary Carcinoma kana ichiramba ichirapwa kenza iri Gemcitabine nekuti inogadzirisa idzo biochemical nzira dzinoita kuti kurapwa kwegomarara risarambe kana kusadaira.

MUCHERO RED RASPBERRY INOKURURWA PAMUSORO PEPUMMELO YEAmpullary Carcinoma UYE KURAPA Gemcitabine.

Sarudza Nut BUTTERNUT kana EUROPEAN CHESTNUT?

Butternut ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seCurcumin, Myricetin, Phloretin, Formononetin, Lycopene. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seMetastasis, NFKB Signaling, Cell Cycle uye Epithelial kune Mesenchymal Transition uye vamwe. Butternut inokurudzirwa kuAmpullary Carcinoma apo chirwere chegomarara chiri kuramba chiri Gemcitabine. Izvi zvinodaro nekuti Butternut inogadzirisa idzo nzira dzebiochemical dzakataurwa nesainzi kuti dzikurudzire maitiro eGemcitabine.

Zvimwe zvezvinhu zvinoshanda kana bioactives muEuropean Chestnut ndeye Quercetin, Ellagic Acid, Curcumin, Myricetin, Phloretin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seOxidative Stress uye TGFB Signaling nevamwe. European Chestnut haikurudzirwe kuAmpullary Carcinoma kana ichiramba ichirapwa kenza iri Gemcitabine nekuti inogadzirisa idzo nzira dzebiochemical dzinoita kuti kurapwa kwegomarara kumire kana kusadaira.

BUTTERNUT INOKURUKURWA PAKATI PAEUROPA CHESTNUT YEAmpullary Carcinoma UYE KURAPA Gemcitabine.

Kune Vanhu Vane Genetic Risk yeCancer

Mubvunzo wakabvunzwa nevanhu vane genetic risk yeAmpullary Carcinoma kana nhoroondo yemhuri ndeye "Chii Chandinofanira Kudya Zvakasiyana Kubva Kare?" uye masarudzire avanofanira kuita zvekudya uye zvekuwedzera kuti vatarise njodzi dzechirwere. Sezvo kune njodzi yegomarara hapana chinogoneka maererano nekurapa - sarudzo dzezvekudya uye zvekuwedzera zvinove zvakakosha uye chimwe chezvinhu zvishoma zvingaite zvinogona kuitwa. Zvese zvinodyarwa-zvikafu hazvina kuenzana uye zvichibva pane zvakazivikanwa genetics uye nzira siginecha - sarudzo dzechikafu nekuwedzera dzinofanirwa kuve munhu.

Sarudza Vegetable WILD LEEK kana TURNIP?

Vegetable Wild Leek ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seCurcumin, Apigenin, Lupeol, Daidzein, Formononetin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical seTGFB Signaling, Oxidative Stress, Cell Cycle uye PI3K-AKT-MTOR Signaling nevamwe. Wild Leek inokurudzirwa kune njodzi yeAmpullary Carcinoma kana njodzi yemajini yakabatana iri APC. Izvi zvinodaro nekuti Wild Leek inowedzera idzo biochemical nzira dzinopokana nemadhiraivha emasaini ayo.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuriwo Turnip ndeye Ellagic Acid, Curcumin, Quercetin, Lupeol, Daidzein. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical senge Oxidative Stress nevamwe. Turnip haikurudzirwe kana njodzi yeAmpullary Carcinoma kana yakabatana genetic njodzi iri APC nekuti inowedzera siginecha nzira dzayo.

MURIWO WWILD LEEK INOKURUKURWA PAKUSHANDA KUTI APC GENETIC RISK YECANCER.

Sarudza Chibereko NANCE kana JUJUBE?

Chibereko Nance chine zvakawanda zvinoshanda zvinosanganisa kana bioactives seCurcumin, Apigenin, Myricetin, Lupeol, Daidzein. Izvi zvinoshandiswa zvinoshandiswa zvinoshandisa nzira dzakasiyana dzebiochemical seTGFB Signaling, RAS-RAF Signaling, Cell Cycle uye PI3K-AKT-MTOR Signaling nevamwe. Nance inokurudzirwa kune njodzi yeAmpullary Carcinoma kana yakabatana genetic njodzi iri APC. Izvi zvinodaro nekuti Nance inowedzera idzo biochemical nzira dzinopokana nemadhiraivha emasaini ayo.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuchero Jujube ndeye Curcumin, Quercetin, Apigenin, Myricetin, Lupeol. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical senge Oxidative Stress, Angiogenesis uye PI3K-AKT-MTOR Signaling nevamwe. Jujube haikurudzirwe kana njodzi yeAmpullary Carcinoma kana yakabatana genetic njodzi iri APC nekuti inowedzera siginecha nzira dzayo.

FRUIT NANCE INAKURUDZWA PAMUSORO JUJUBE YEAPC GENETIC RISK OF CANCER.

Sarudza Nut COMMON HAZELNUT kana CHESTNUT?

Common Hazelnut ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seCurcumin, Quercetin, Myricetin, Lupeol, Daidzein. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seAngiogenesis, RAS-RAF Signaling, Cell Cycle uye PI3K-AKT-MTOR Signaling nevamwe. Common Hazelnut inokurudzirwa kune njodzi yeAmpullary Carcinoma kana yakabatana genetic njodzi iri APC. Izvi zvinodaro nekuti Common Hazelnut inowedzera idzo biochemical nzira dzinopokana nemadhiraivha emasaini ayo.

Zvimwe zvezvinhu zvinoshanda kana bioactives muChestnut ndeyeEllagic Acid, Curcumin, Apigenin, Myricetin, Lupeol. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical senge Oxidative Stress, Stem Cell Signaling uye TGFB Signaling nevamwe. Chestnut haikurudzirwe kana njodzi yeAmpullary Carcinoma kana yakabatana genetic njodzi iri APC nekuti inowedzera siginecha nzira dzayo.

COMMON HAZELNUT INOKURUDZWA PAMUSORO PACHESTNUT YEAPC GENETIC RISK YECANCER.

Mhedziso

Chikafu uye Zvekuwedzera zvakasarudzwa sarudzo dzakakosha kune cancer seAmpullary Carcinoma. Ampullary Carcinoma varwere uye vanhu vane genetic-njodzi vanogara vaine mubvunzo uyu: "Ndezvipi zvekudya uye zvinovaka muviri zvinokurudzirwa kwandiri uye izvo zvisiri?" Pane chitendero chakajairika chinova fungidziro isiriyo yekuti zvese zvinodyarwa-zvikafu zvinogona kubatsira kana kwete asi zvisingakuvadze. Zvimwe zvekudya uye zvekuwedzera zvinogona kukanganisa marapirwo egomarara kana kusimudzira mamorekuru enzira yegomarara.

Kune marudzi akasiyana ezviratidzo zvegomarara senge Ampullary Carcinoma, imwe neimwe iine bundu genetics ine mamwe ma genomic musiyano pamunhu wega wega. Kuwedzera kurapwa kwegomarara uye chemotherapy ine yakasarudzika nzira yekuita. Chikafu chega chega seGiant Butterbur chine mabioactive akasiyana muhuwandu hwakasiyana, izvo zvine chekuita neakasiyana uye akasiyana seti yebiochemical nzira. Tsanangudzo yekudya yakasarudzika ndeyakasarudzika chikafu kurudziro yegomarara chiratidzo, marapirwo, genetics, mararamiro uye zvimwe zvinhu. Sarudzo dzehutano hwemunhu hwegomarara dzinoda ruzivo rwegomarara biology, sainzi yechikafu uye kunzwisisa kweakasiyana chemotherapy marapirwo. Chekupedzisira kana paine shanduko yekurapa kana nyowani genomics inoonekwa - iyo inovaka muviri inoda kuongororwazve.

Iyo addon nutrition personalization mhinduro inoita kuti sarudzo ive nyore uye inobvisa zvese zvekufungidzira mukupindura mubvunzo, "Ndezvipi zvekudya zvandinofanira kusarudza kana kusasarudzira Ampullary Carcinoma?". Iyo addon yakawanda-yekuranga timu inosanganisira varapi vegomarara, masayendisiti ekiriniki, mainjiniya esoftware uye masayendisiti edata.

References

• Msk Impact 2017
• Cancer therapy inoumba kusimba kwenzvimbo ye clonal hematopoiesis.
• Mafungiro matsva mu phospholipase D kusaina mukuzvimba uye cancer.
• Dietary compound isoliquiritigenin inotarisa GRP78 kuchemosensitize kenza yemazamu stem masero kuburikidza ne β-catenin/ABCG2 kusaina.
• Daidzein mhedzisiro pahomoni refractory prostate cancer in vitro uye in vivo ichienzaniswa negenistein uye soy inobvisa: kugona kweradiotherapy.