ziviso
Chikafu cheKuputa Multiple Myeloma chinofanirwa kuve chakasarudzika kune wega wega uye zvakare chinofanirwa kuchinjika kana kenza kurapwa kana bundu genetic shanduko. Iyo yemunhu uye kugadzirisa kunofanirwa kufunga nezvese zvinoshanda zvinosanganiswa kana bioactives zviri muzvokudya zvakasiyana zvine chekuita negomarara biology, genetics, marapirwo, mararamiro uye zvido zvekudya. Saka nepo chikafu chiri chimwe chezvisarudzo zvakakosha zvemurwere wegomarara uye munhu ari panjodzi yegomarara - kusarudza chikafu chekudya harisi basa riri nyore.
Kusvuta kwakawanda myeloma (SMM) chirwere cheprecancerous chinowanzoonekwa sechikamu chepakati pakati peMGUS (monoclonal gammopathy yekukosha kusingazivikanwi) uye inoshanda yakawanda myeloma, ine maitiro akasiyana uye ICD-10 kodhi chaiyo yekurekodha kurapwa. Kunzwisisa mutsauko uripo pakati pekuputa myeloma nemultiple myeloma kwakakosha, sezvo zvichisiyana maererano nezviratidzo, nzira dzekurapa, uye kufungidzira. Kusvuta akawanda myeloma zviratidzo kazhinji hazvina kusimba pane izvo zvemyeloma yakazara-inoputika asi zvinogona kusanganisira kuneta uye zvimwe zvisingaoneki zviratidzo. Kuongororwa kweSMM kunoenderana nemaitiro chaiwo, ayo anotsanangurwa mune dzakasiyana zviwanikwa zvekurapa, kusanganisira pathology rondedzero. Iyo inopfungaira yakawanda myeloma prognosis uye chiyero chekupona chinogona kusiyana zvakanyanya, zvichipesvedzerwa nezvakasiyana zvinhu zvakaita sekukura kwechirwere uye hutano hwemunhu. Kurapa kweSMM kunowanzo chengetedza zvakanyanya kana zvichienzaniswa neyakawanda myeloma, kazhinji inosanganisira kunyatsotarisisa uye dzimwe nguva miedzo yekiriniki yekuputa akawanda myeloma, ayo anoongorora nzira nyowani dzekurapa. Iyi miedzo yekiriniki yakakosha mukusimudzira kunzwisisa kwedu uye manejimendi echirwere ichi, zvichizotungamira kune mamwe marapirwo anoshanda mune ramangwana.
Zvekusvuta Multiple Myeloma zvine basa here kuti miriwo, michero, nzungu, mhodzi anodya chii?
Mubvunzo wakajairika wekudya unobvunzwa nevarwere vegomarara uye vanhu vari pa-genetic njodzi yegomarara ndeye - yegomarara seSmoldering Multiple Myeloma zvine basa here kuti ndechipi chikafu chandinodya uye chandisingade? Kana kuti kana ndikatevera kudya-kwekudyara kunokwana kenza seSmoldering Multiple Myeloma?
Semuenzaniso zvine basa here kana muriwo weBrussels Sprouts uchidyiwa zvakanyanya uchienzaniswa neCardoon? Zvinoita mutsauko here kana muchero Lime inosarudzwa pane Kiwi? Zvakare kana sarudzo dzakafanana dzakaitirwa nzungu/mhodzi dzakaita seButternut pamusoro peChestnut uye dzemapunzi seBroad Bean pamusoro peMoth Bean. Uye kana izvo zvandinodya zvine basa - zvino munhu anoona sei chikafu chinokurudzirwa kuSmoldering Multiple Myeloma uye ndiyo mhinduro imwechete kune wese ane chirwere chakafanana kana genetic njodzi?
Ehe! Zvokudya zvaunodya zvine chekuita neSmoldering Multiple Myeloma!
Mazano echikafu anogona kunge asina kufanana kune wese munhu uye anogona kuve akasiyana kunyangwe kune imwechete kuongororwa uye genetic njodzi.
Zvokudya zvose (miriwo, michero, nzungu, mhodzi, pulses, mafuta nezvimwewo) uye zvokudya zvinovaka muviri zvinoumbwa nezvinodarika imwe inoshanda mamolecular ingredient kana bio-actives muzvikamu zvakasiyana uye uwandu. Chinhu chimwe nechimwe chinoshanda chine nzira yakasarudzika yekuita - iyo inogona kuve activation kana inhibition yeakasiyana biochemical nzira. Zvikafu zvakangotaurwa uye zvekuwedzera izvo zvinokurudzirwa ndezviya zvisingakonzere kuwedzera kwemamorekuru anotyaira cancer asi anodzideredza. Zvikasadaro izvo zvikafu hazvifanirwe kukurudzirwa. Chikafu chine akawanda anoshanda zvinongedzo - saka kana uchiongorora chikafu uye zvekuwedzera iwe unofanirwa kufunga nezve mabatiro ezvese zvinoshanda zvinongedzo zvakapetwa kwete zvega.
Semuenzaniso Lime ine zvinoshanda zvinosanganisa Isoliquiritigenin, Curcumin, Catechol, Lycopene, Melatonin. Uye Kiwi ine zvinoshanda zvinosanganisa Kaempferol, Isoliquiritigenin, Curcumin, Catechol, Melatonin uye pamwe nevamwe.
Chikanganiso chinowanzoitwa pakusarudza nekusarudza chikafu chekudya cheSmoldering Multiple Myeloma - ndeyekuongorora chete zvakasarudzwa zvinoshandiswa zviri muzvokudya uye kufuratira zvimwe. Nekuti zvakasiyana-siyana zvinoshanda zviri mukudya zvinogona kuva nemhedzisiro inopikisa kune vatyairi vegomarara - haugone kutora cherry inoshanda mukudya uye ma supplements ekuita sarudzo yehutano hweSmoldering Multiple Myeloma.
HONGU – ZVOKUSARUDZA ZVOKUDYA ZVINOKOSHA NEGONSA. ZVISARUDZO ZVOKUDYA ZVINOFANIRA KUFUNGA ZVINHU ZVINHU ZVINHU ZVINOSHANDA PACHIDYA.
Hunyanzvi hunodiwa paKudya Kwekudya Kwemunhu Wekuputa Multiple Myeloma?
Kudya kwakasarudzika kwegomarara senge Smoldering Multiple Myeloma ine zvinokurudzirwa zvekudya / zvinowedzera; zvisingakurudzirwe chikafu / ma supplements ane semuenzaniso mabikirwo anotungamira kushandiswa kwezvikafu zvinokurudzirwa. Muenzaniso wekudya kwakasiyana-siyana unogona kuonekwa pane izvi batanidzo.
Kufunga kuti ndezvipi zvekudya zvinokurudzirwa kana kwete zvakaomesesa, zvinoda hunyanzvi muSmoldering Multiple Myeloma biology, sainzi yechikafu, genetics, biochemistry pamwe nekunzwisisa kwakanaka kwemashandiro anoita marapirwo egomarara uye kusagadzikana kwakabatana uko kurapwa kwaigona kumira kushanda.
ZVINONYANYA ZVINONYANYA ZVINODIWA KUTI ZVINOVAKA ZVINOVAKA MUNHU ZVINHU ZVINHU ZVINOITA: CANCER BIOLOGY, FOOD SCIENCE, KURAPA MAKANZA UYE GENETICS.
Chikafu chekudya Mushure meKenza Kuongorora!
Hapana kanzura mbiri dzakafanana. Enda pamusoro peyakajairwa nhungamiro yemunhu wese uye utore sarudzo dzakagadzirirwa nezve chikafu uye zvinowedzerwa uine chivimbo.
Hunhu hwegomarara senge Smoldering Multiple Myeloma
Magomarara ese akaita seSmoldering Multiple Myeloma anogona kuratidzirwa neyakasiyana seti ye biochemical nzira - siginecha nzira dzeSmoldering Multiple Myeloma. Biochemical nzira senge Amino Acid Metabolism, NFKB Signaling, PI3K-AKT-MTOR Signaling, Hypoxia chikamu cheiyo siginecha tsananguro yeSmoldering Multiple Myeloma. Kenza yemunhu wega genetics inogona kuve yakasiyana uye nekudaro siginicha yavo yegomarara inogona kuve yakasarudzika.
Kurapa kunoshanda kuSmoldering Multiple Myeloma kunofanirwa kuve nekuziva nezve inobatanidzwa siginecha biochemical nzira kune yega yega murwere wegomarara uye munhu ari panjodzi yemajini. Saka marapirwo akasiyana ane maitiro akasiyana ezviito anoshanda kune varwere vakasiyana. Saizvozvo uye nekuda kwezvikonzero zvakafanana zvekudya uye zvekuwedzera zvinoda kuitirwa munhu wega wega. Saka zvimwe zvekudya uye zvekuwedzera zvinokurudzirwa kuSmoldering Multiple Myeloma kana uchitora kurapwa gomarara Lenalidomide, uye zvimwe zvekudya nekuwedzera hazvikurudzirwe.
Sources like cBioPortal uye vamwe vazhinji vanopa mumiriri wehuwandu hwevarwere data risingazivikanwe kubva kukiriniki miedzo yezvese zviratidzo zvegomarara. Iyi dhata ine yekiriniki yekuongorora yeruzivo senge sampuli saizi / nhamba yevarwere, mapoka ezera, murume kana mukadzi, dzinza, marapirwo, bundu saiti uye chero genetic mutations.
BRCA2, IRS2, CDK8, RB1 uye LCP1 ndiwo epamusoro akaverengerwa majini eSmoldering Multiple Myeloma. BRCA2 inoshumwa mu45.0% yevanomiririra varwere mukati meyese miedzo yekiriniki. Uye IRS2 inoshumwa mu45.0%. Iyo yakasanganiswa yehuwandu hwevarwere data inovhara mazera kubva kusvika . % yedata revarwere vanoonekwa sevarume. Iyo Smoldering Multiple Myeloma biology pamwe neyakashumwa genetics pamwe chete inotsanangura huwandu hwevanhu vanomiririrwa siginecha biochemical nzira dzegomarara iri. Kana iyo yega cancer tumor genetics kana majini anokonzera njodzi achizivikanwawo saka izvo zvinofanirwa kushandiswawo kune hutano hwemunhu.
ZVAKASARUDZA KUDYA ZVINODYA ZVINOFANIRA KUFANIRA NEMUNHU WEMUNHU WEMUNHU WEMUNHU WEGONSI.
Chikafu uye Zvekuwedzera Zvekuputa Multiple Myeloma
Kune Varwere veCancer
Varwere vegomarara vari pakurapa kana pakuchengeta palliative vanofanira kuita sarudzo pazvekudya uye zvekuwedzera - zvemacalorie anodiwa ekudya, kubata chero mhedzisiro yekurapa uyezve nekugadzirisa kenza. Zvese zvinodyarwa-zvikafu hazvina kuenzana uye kusarudza uye kuisa pamberi pezvikafu zvakagadzirirwa munhu uye zvakagadzirirwa kuenderera mberi kurapwa kwegomarara kwakakosha uye kwakaoma. Heano mimwe mienzaniso inopa nhungamiro yekuita sarudzo dzekudya.
Sarudza Vegetable BRUSSEL sprouts kana CARDOON?
Vegetable Brussel Sprouts ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seIsoliquiritigenin, Curcumin, Catechol, Melatonin, Daidzein. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seSero Cycle, Cell Survival, P53 Signaling uye Angiogenesis nevamwe. Brussel Sprouts inokurudzirwa kuSmoldering Multiple Myeloma apo chirwere chegomarara chiri kuramba chiri kuLenalidomide. Izvi zvinodaro nekuti Brussel Sprouts inogadzirisa idzo nzira dzebiochemical dzakataurwa nesainzi kuti dzigonese mhedzisiro yeLenalidomide.
Zvimwe zvezvinhu zvinoshanda kana bioactives mumuriwo Cardoon ndeapigenin, Kaempferol, Isoliquiritigenin, Curcumin, Catechol. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical seOncogenic Histone Methylation, Oncogenic Cancer Epigenetics uye NFKB Signaling nevamwe. Cardoon haikurudzirwe kuSmoldering Multiple Myeloma kana ichiramba ichirapwa gomarara iri Lenalidomide nekuti inogadzirisa nzira dzebiochemical dziya dzinoita kuti kurapwa kwegomarara kusamirire kana kusadaira.
MIRIWO YEBRUSSEL NZIRA INOKURUDZWA PAMUSORO PECARDOON YEKUPITISA Multiple Myeloma UYE KURAPA Lenalidomide.
Sarudza Chibereko KIWI kana LIME?
Chibereko Kiwi ine akawanda anoshanda zvinosanganisa kana bioactives seKaempferol, Isoliquiritigenin, Curcumin, Catechol, Melatonin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical seSero Cycle, Hypoxia uye P53 Signaling nevamwe. Kiwi inokurudzirwa kuSmoldering Multiple Myeloma kana iri kuramba ichirapwa gomarara iri Lenalidomide. Izvi zvinodaro nekuti Kiwi inogadzirisa idzo nzira dzebiochemical dzakataurwa nesainzi kuti dzikurudzire maitiro eLenalidomide.
Zvimwe zvezvinhu zvinoshanda kana bioactives mumuchero Lime ndeyeIsoliquiritigenin, Curcumin, Catechol, Lycopene, Melatonin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seWNT Beta Catenin Signaling, Microtubule Dynamics uye NFKB Signaling nevamwe. Lime haikurudzirwe kuSmoldering Multiple Myeloma kana ichiramba ichirapwa gomarara iri Lenalidomide nekuti inogadzirisa idzo biochemical nzira dzinoita kuti kurapwa kwegomarara kurambe kana kusadaira.
MUCHERO KIWI INOKURUKURWA PAMUSORO PE LIME PAKUPVISA Multiple Myeloma UYE KURAPA Lenalidomide.
Sarudza Nut BUTTERNUT kana CHESTNUT?
Butternut ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seApigenin, Kaempferol, Isoliquiritigenin, Curcumin, Catechol. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical dzakadai seDNA Kugadzirisa, Cell Cycle, Angiogenesis uye Microtubule Dynamics nevamwe. Butternut inokurudzirwa kuSmoldering Multiple Myeloma apo chirwere chegomarara chiri kuramba chiri kuLenalidomide. Izvi zvinodaro nekuti Butternut inogadzirisa idzo nzira dzebiochemical dzakataurwa nesainzi kuti dzikurudzire maitiro eLenalidomide.
Zvimwe zvezvinhu zvinoshanda kana bioactives muChestnut ndeye Apigenin, Kaempferol, Isoliquiritigenin, Curcumin, Catechol. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seDNA Kugadzirisa uye WNT Beta Catenin Signaling uye nevamwe. Chestnut haikurudzirwe kuSmoldering Multiple Myeloma kana ichiramba ichirapwa gomarara iri Lenalidomide nekuti inoshandura nzira dzebiochemical dziya dzinoita kuti kurapwa kwegomarara kusamirire kana kusadaira.
BUTTERNUT INOKURUKUDZWA PAMUSORO PECHESTNUT YEKUSvuta Multiple Myeloma UYE KURAPA Lenalidomide.
Kune Vanhu Vane Genetic Risk yeCancer
Mubvunzo wakabvunzwa nevanhu vane genetic risk yeSmoldering Multiple Myeloma kana nhoroondo yemhuri ndeye "Chii Chandinofanira Kudya Zvakasiyana Kubva Kare?" uye masarudzire avanofanira kuita zvekudya uye zvekuwedzera kuti vatarise njodzi dzechirwere. Sezvo kune njodzi yegomarara hapana chinogoneka maererano nekurapa - sarudzo dzezvekudya uye zvekuwedzera zvinove zvakakosha uye chimwe chezvinhu zvishoma zvingaite zvinogona kuitwa. Zvese zvinodyarwa-zvikafu hazvina kuenzana uye zvichibva pane zvakazivikanwa genetics uye nzira siginecha - sarudzo dzechikafu nekuwedzera dzinofanirwa kuve munhu.
Sarudza Vegetable ORANGE BELL PEPPER kana CAROB?
Vegetable Orange Bell Pepper ine zvakawanda zvinoshanda zvinoshandiswa kana bioactives seApigenin, Curcumin, Lupeol, Daidzein, Formononetin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical senge DNA Kugadzirisa, Cell Cycle, Cell Cycle Checkpoints uye MYC Signaling nevamwe. Orange Bell Pepper inokurudzirwa kune njodzi yekusvuta Multiple Myeloma kana yakabatana genetic njodzi iri BRCA2. Izvi zvinodaro nekuti Orange Bell Pepper inowedzera idzo biochemical nzira dzinopokana nemadhiraivha emasaini ayo.
Zvimwe zvezvinhu zvinoshanda kana bioactives mumuriwo weCarob ndeye Apigenin, Curcumin, Lupeol, Daidzein, Quercetin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical seDNA Kugadzirisa uye Kukura Kwechinhu Chiratidzo uye nevamwe. Carob haikurudzirwe kana njodzi yeSmoldering Multiple Myeloma kana yakabatana genetic njodzi iri BRCA2 nekuti inowedzera siginicha nzira dzayo.
MURIWO ORANGE BELL PEPPER INOKURUDZWA PAMUSORO PECAROB KUTI BRCA2 GENETIC RISK YECANCER.
Sarudza Chibereko JAVA PLUM kana GRAPEFRUIT?
Chibereko Java Plum ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seApigenin, Curcumin, Ellagic Acid, Lupeol, Daidzein. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seSero Cycle, P53 Signaling, DNA Repair uye Angiogenesis nevamwe. Java Plum inokurudzirwa kune njodzi yeSmoldering Multiple Myeloma kana yakabatana genetic njodzi iri BRCA2. Izvi zvinodaro nekuti Java Plum inowedzera idzo biochemical nzira dzinopokana nemadhiraivha emasaini ayo.
Zvimwe zvezvinhu zvinoshanda kana bioactives mumuchero Grapefruit ndeye Curcumin, Lupeol, Daidzein, Formononetin, Naringin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical dzakadai seDNA Kugadzirisa, Stem Cell Signaling uye Kukura Factor Signaling nevamwe. Grapefruit haikurudzirwe kana njodzi yeSmoldering Multiple Myeloma kana yakabatana genetic njodzi iri BRCA2 nekuti inowedzera siginecha nzira dzayo.
CHICHERO JAVA PLUM INOKURUKUDZWA PAMUSORO PAMUSORO PERAPEFRUIT YEBRCA2 GENETIC RISK YECANCER.
Sarudza Nut COMMON HAZELNUT kana EUROPEAN CHESTNUT?
Common Hazelnut ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seCurcumin, Lupeol, Daidzein, Quercetin, Formononetin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical senge DNA Kugadzirisa, Cell Cycle, Angiogenesis uye Stem Cell Signaling nevamwe. Common Hazelnut inokurudzirwa kune njodzi yekusvuta Multiple Myeloma kana yakabatana genetic njodzi iri BRCA2. Izvi zvinodaro nekuti Common Hazelnut inowedzera idzo biochemical nzira dzinopokana nemadhiraivha emasaini ayo.
Zvimwe zvezvinhu zvinoshanda kana bioactives muEuropean Chestnut ndeye Apigenin, Curcumin, Ellagic Acid, Lupeol, Daidzein. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical seDNA Kugadzirisa uye Stem Cell Signaling nevamwe. European Chestnut haikurudzirwe kana njodzi yekusvuta Multiple Myeloma kana yakabatana genetic njodzi iri BRCA2 nekuti inowedzera siginecha nzira dzayo.
COMMON HAZELNUT INOKURUDZWA PAMUSORO PEEUROPA CHESTNUT YEBRCA2 GENETIC RISK YECANCER.
Mhedziso
Zvokudya uye Zvekuwedzera zvakasarudzwa sarudzo dzakakosha dzegomarara seSmoldering Multiple Myeloma. Kusvuta Multiple Myeloma varwere uye vanhu vane genetic-njodzi vanogara vaine mubvunzo uyu: "Ndezvipi zvekudya uye zvinovaka muviri zvinokurudzirwa kwandiri uye izvo zvisiri?" Pane chitendero chakajairika chinova fungidziro isiriyo yekuti zvese zvinodyarwa-zvikafu zvinogona kubatsira kana kwete asi zvisingakuvadze. Zvimwe zvekudya uye zvekuwedzera zvinogona kukanganisa marapirwo egomarara kana kusimudzira mamorekuru enzira yegomarara.
Kune marudzi akasiyana ezviratidzo zvegomarara senge Smoldering Multiple Myeloma, imwe neimwe iine bundu genetics ine mamwe ma genomic akasiyana pamunhu wega wega. Kuwedzera kurapwa kwegomarara uye chemotherapy ine yakasarudzika nzira yekuita. Chikafu chega chega seBrussel Sprouts chine akasiyana bioactives muhuwandu hwakasiyana, izvo zvine chekuita pane akasiyana uye akasiyana seti e biochemical nzira. Tsanangudzo yekudya yakasarudzika ndeyakasarudzika chikafu kurudziro yegomarara chiratidzo, marapirwo, genetics, mararamiro uye zvimwe zvinhu. Sarudzo dzehutano hwemunhu hwegomarara dzinoda ruzivo rwegomarara biology, sainzi yechikafu uye kunzwisisa kweakasiyana chemotherapy marapirwo. Chekupedzisira kana paine shanduko yekurapa kana nyowani genomics inoonekwa - iyo inovaka muviri inoda kuongororwazve.
Iyo addon nutrition personalization mhinduro inoita kuti sarudzo ive nyore uye inobvisa zvese zvekufungidzira mukupindura mubvunzo, "Ndezvipi zvekudya zvandinofanira kusarudza kana kusasarudza zveSmoldering Multiple Myeloma?". Iyo addon yakawanda-yekuranga timu inosanganisira varapi vegomarara, masayendisiti ekiriniki, mainjiniya esoftware uye masayendisiti edata.
Hunhu Hwakakosheswa Nekamwe Kenza!
Gomarara rinoshanduka nekufamba kwenguva. Gadzirisa uye gadzirisa chikafu chako zvichibva pachiratidzo chegomarara, marapirwo, mararamiro, zvaunofarira zvekudya, allergies uye zvimwe zvinhu.
References
- Mhedzisiro ye isoliquiritigenin pamasero egomarara reovarian.
- Brassinin inhibits STAT3 yekusaina nzira kuburikidza nemodulation yePIAS-3 uye SOCS-3 kutaura uye inosimbisa kenza yemapapu yemunhu xenograft mu nude mice kuenda paclitaxel.
- Gallic acid inomutsa kukuvara kweDNA uye inodzvanya DNA kugadzirisa gene kutaura mukenza yeprostate yemunhu PC-3 masero.
- Betulinic acid inhibits stemness uye EMT yepancreatic cancer maseru kuburikidza ne activation ye AMPK kusaina.
- Modulation yeHER2 kutaura neferulic acid pagomarara rezamu remunhu MCF7 masero.
- Anti-inflammatory uye anticarcinogenic effect ye genistein yega kana pamwe chete ne capsaicin muTPA-inorapwa rat mammary glands kana mammary cancer cell line.
- Negative regulation ye signal transducer uye activator ye transcription-3 signing cascade ne lupeol inhibits kukura uye induces apoptosis muhepatocellular carcinoma masero.