Zvokudya zveSystemic Mastocytosis!

ziviso

Zvikafu zveSystemic Mastocytosis zvinofanirwa kuve zvakasarudzika kune wega wega uye zvakare zvinofanirwa kuchinjika kana kenza kurapwa kana bundu genetic shanduko. Iyo yemunhu uye kugadzirisa kunofanirwa kufunga nezvese zvinoshanda zvinosanganiswa kana bioactives zviri muzvokudya zvakasiyana zvine chekuita negomarara biology, genetics, marapirwo, mararamiro uye zvido zvekudya. Saka nepo chikafu chiri chimwe chezvisarudzo zvakakosha zvemurwere wegomarara uye munhu ari panjodzi yegomarara - kusarudza chikafu chekudya harisi basa riri nyore.

Kune Systemic Mastocytosis zvine basa here kuti miriwo, michero, nzungu, mbeu inodya chii?

Mubvunzo wakajairika wekudya unobvunzwa nevarwere vegomarara uye vanhu vari pa-genetic njodzi yegomarara ndeye - yegomarara seSystemic Mastocytosis zvine basa kuti ndechipi chikafu chandinodya uye chandisingade? Kana kuti ndikatevera kudya-kwekudyara kunokwana kenza seSystemic Mastocytosis?

Semuenzaniso zvine basa here kana muriwo weBrussels Sprouts uchidyiwa zvakanyanya zvichienzaniswa neTunip? Zvinoita mutsauko here kana muchero Fig uchifarirwa pane Rabbiteye Blueberry? Zvakare kana sarudzo dzakafanana dzakaitirwa nzungu/mhodzi seBlack Walnut pamusoro peChestnut uye nemapuruzi seChickpea pamusoro peCatjang Pea. Uye kana izvo zvandinodya zvine basa - zvino munhu anoona sei zvikafu zvinokurudzirwa Systemic Mastocytosis uye ndiyo mhinduro imwechete kune wese munhu ane chirwere chakafanana kana genetic njodzi?

Ehe! Zvokudya zvaunodya zvine chekuita neSystemic Mastocytosis!

Mazano echikafu anogona kunge asina kufanana kune wese munhu uye anogona kuve akasiyana kunyangwe kune imwechete kuongororwa uye genetic njodzi.

Zvokudya zvose (miriwo, michero, nzungu, mhodzi, pulses, mafuta nezvimwewo) uye zvokudya zvinovaka muviri zvinoumbwa nezvinodarika imwe inoshanda mamolecular ingredient kana bio-actives muzvikamu zvakasiyana uye uwandu. Chinhu chimwe nechimwe chinoshanda chine nzira yakasarudzika yekuita - iyo inogona kuve activation kana inhibition yeakasiyana biochemical nzira. Zvikafu zvakangotaurwa uye zvekuwedzera izvo zvinokurudzirwa ndezviya zvisingakonzere kuwedzera kwemamorekuru anotyaira cancer asi anodzideredza. Zvikasadaro izvo zvikafu hazvifanirwe kukurudzirwa. Chikafu chine akawanda anoshanda zvinongedzo - saka kana uchiongorora chikafu uye zvekuwedzera iwe unofanirwa kufunga nezve mabatiro ezvese zvinoshanda zvinongedzo zvakapetwa kwete zvega.

Semuenzaniso Fig ine inoshanda zvinoshandiswa Isoliquiritigenin, Quercetin, Kaempferol, Taxifolin, Curcumin. Uye Rabbiteye Blueberry ine zvinoshanda zvinosanganisa Quercetin, Linalool, Geraniol, Gallic Acid, Ferulic Acid uye zvimwe zvimwe.

Chikanganiso chakajairika pakusarudza nekusarudza chikafu chekudya cheSystemic Mastocytosis - kuongorora chete zvakasarudzwa zvinoshandiswa zviri muzvokudya uye kufuratira zvimwe. Nekuti zvakasiyana-siyana zvinoshanda zviri mukudya zvinogona kuve nemhedzisiro inopikisa kune vatyairi vegomarara - haugone cherry kutora zvinoshanda mukudya uye ma supplements ekuita sarudzo yekudya kune Systemic Mastocytosis.

HONGU – ZVOKUSARUDZA ZVOKUDYA ZVINOKOSHA NEGONSA. ZVISARUDZO ZVOKUDYA ZVINOFANIRA KUFUNGA ZVINHU ZVINHU ZVINHU ZVINOSHANDA PACHIDYA.

Unyanzvi hunodiwa paKudya Kwekudya Kwemunhu kune Systemic Mastocytosis?

Kudya kwakasarudzika kwekenza seSystemic Mastocytosis ine zvinokurudzirwa zvekudya / zvinowedzera; zvisingakurudzirwe chikafu / ma supplements ane semuenzaniso mabikirwo anotungamira kushandiswa kwezvikafu zvinokurudzirwa. Muenzaniso wekudya kwakasiyana-siyana unogona kuonekwa pane izvi batanidzo.

Kufunga kuti ndezvipi zvekudya zvinokurudzirwa kana kwete zvakaomesesa, zvinoda hunyanzvi muSystemic Mastocytosis biology, sainzi yechikafu, genetics, biochemistry pamwe nekunzwisisa kwakanaka kwemashandiro anoita marapirwo egomarara uye kusagadzikana kwakabatana uko kurapwa kwaigona kumira kushanda.

ZVINONYANYA ZVINONYANYA ZVINODIWA KUTI ZVINOVAKA ZVINOVAKA MUNHU ZVINHU ZVINHU ZVINOITA: CANCER BIOLOGY, FOOD SCIENCE, KURAPA MAKANZA UYE GENETICS.

Hunhu hwegomarara seSystemic Mastocytosis

Ese magomarara seSystemic Mastocytosis anogona kuratidzirwa neyakasiyana seti yebiochemical nzira - iyo siginecha nzira dzeSystemic Mastocytosis. Nzira dzeBiochemical dzakadai seJAK-STAT Signaling, MAPK Signaling, PI3K-AKT-MTOR Signaling, RAS-RAF Signaling chikamu chetsanangudzo yeSistimu yeSystemic Mastocytosis. Kenza yemunhu wega genetics inogona kuve yakasiyana uye nekudaro siginicha yavo yegomarara inogona kuve yakasarudzika.

Kurapa kunoshanda kweSystemic Mastocytosis kunoda kuziva nzira yakabatana nayo siginecha yebiochemical yemurwere wega wega wegomarara uye munhu ari panjodzi yemagene. Saka marapirwo akasiyana ane maitiro akasiyana ezviito anoshanda kune varwere vakasiyana. Saizvozvo uye nekuda kwezvikonzero zvakafanana zvekudya uye zvekuwedzera zvinoda kuitirwa munhu wega wega. Saka zvimwe zvekudya uye zvekuwedzera zvinokurudzirwa kuSystemic Mastocytosis kana uchitora kurapwa kenza Midostaurin, uye zvimwe zvekudya uye zvekuwedzera hazvikurudzirwe.

Sources like cBioPortal uye vamwe vazhinji vanopa mumiriri wehuwandu hwevarwere data risingazivikanwe kubva kukiriniki miedzo yezvese zviratidzo zvegomarara. Iyi dhata ine yekiriniki yekuongorora yeruzivo senge sampuli saizi / nhamba yevarwere, mapoka ezera, murume kana mukadzi, dzinza, marapirwo, bundu saiti uye chero genetic mutations.

CNOT3, DNMT3A, FLT3, NPM1 neKIT ndiwo epamusoro akaverengerwa majini eSystemic Mastocytosis. CNOT3 inoshumwa mu50.0% yevanomiririra varwere mumakiriniki ese miedzo. Uye DNMT3A inotaurwa mu50.0%. Iyo yakasanganiswa yehuwandu hwevarwere data inovhara mazera kubva kusvika . 100.0% yedata revarwere vanoonekwa sevarume. Iyo Systemic Mastocytosis biology pamwe neyakashumwa genetics pamwechete inotsanangura huwandu hwevanhu hunomiririrwa siginecha biochemical nzira dzegomarara iri. Kana iyo yega cancer tumor genetics kana majini anokonzera njodzi achizivikanwawo saka izvo zvinofanirwa kushandiswawo kune hutano hwemunhu.

ZVAKASARUDZA KUDYA ZVINODYA ZVINOFANIRA KUFANIRA NEMUNHU WEMUNHU WEMUNHU WEMUNHU WEGONSI.

Chikafu uye Zvekuwedzera zveSystem Mastocytosis

Kune Varwere veCancer

Varwere vegomarara vari pakurapa kana pakuchengeta palliative vanofanira kuita sarudzo pazvekudya uye zvekuwedzera - zvemacalorie anodiwa ekudya, kubata chero mhedzisiro yekurapa uyezve nekugadzirisa kenza. Zvese zvinodyarwa-zvikafu hazvina kuenzana uye kusarudza uye kuisa pamberi pezvikafu zvakagadzirirwa munhu uye zvakagadzirirwa kuenderera mberi kurapwa kwegomarara kwakakosha uye kwakaoma. Heano mimwe mienzaniso inopa nhungamiro yekuita sarudzo dzekudya.

Sarudza Vegetable BRUSSEL sprouts kana TURNIP?

Vegetable Brussel Sprouts ine zvakawanda zvinoshanda zvinoshandiswa kana bioactives seIsoliquiritigenin, Taxifolin, Sulforaphane, Curcumin, Lupeol. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana-siyana dzebiochemical sePI3K-AKT-MTOR Kuratidzira, MAPK Kuratidzira, Oncogenic Cancer Epigenetics uye MYC Signaling nevamwe. Brussel Sprouts inokurudzirwa kuSystemic Mastocytosis kana ichienderera mberi kurapwa kwegomarara iri Midostaurin. Izvi zvinodaro nekuti Brussel Sprouts inogadzirisa idzo nzira dzebiochemical dzakataurwa nesainzi kuti dzikurudzire mashandiro eMidostaurin.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuriwo Turnip ndeyeIsoliquiritigenin, Quercetin, Kaempferol, Taxifolin, Ellagic Acid. Izvi zvinoshandiswa zvinosanganisa zvinoshandisa nzira dzakasiyana dzebiochemical seMYC Signaling, MAPK Signaling uye PI3K-AKT-MTOR Signaling nevamwe. Turnip haikurudzirwe kuSystemic Mastocytosis kana ichienderera mberi kurapwa kwegomarara iri Midostaurin nekuti inogadzirisa idzo biochemical nzira dzinoita kuti kurapwa kwegomarara rirambe kana kusadaira.

MIRIWO YEBRUSSEL ZVINOKUDZWA PAMUSORO PAMUSORO PAMUSORO PESystem Mastocytosis UYE KURAPA Midostaurin.

Sarudza Chibereko RABBITEYE BLUEBERRY kana FIG?

Chibereko Rabbiteye Blueberry ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seQuercetin, Linalool, Geraniol, Gallic Acid, Ferulic Acid. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical seMAPK Signaling uye PI3K-AKT-MTOR Signaling uye vamwe. Rabbiteye Blueberry inokurudzirwa kuSystemic Mastocytosis kana ichienderera mberi kurapwa kwegomarara iri Midostaurin. Izvi zvinodaro nekuti Rabbiteye Blueberry inogadzirisa idzo nzira dzebiochemical dzakataurwa nesainzi kuti dzikurudzire maitiro eMidostaurin.

Zvimwe zvezvishandiso zvinoshandiswa kana bioactives mumuchero Fig is Isoliquiritigenin, Quercetin, Kaempferol, Taxifolin, Curcumin. Izvi zvinoshandiswa zvinoshandiswa zvinoshandisa nzira dzakasiyana-siyana dzebiochemical seMAPK Signaling uye PI3K-AKT-MTOR Signaling uye vamwe. Fig haina kukurudzirwa yeSystemic Mastocytosis kana ichienderera mberi kurapwa kwegomarara iri Midostaurin nekuti inogadzirisa idzo biochemical nzira dzinoita kuti kurapwa kwegomarara kurambe kana kusadaira.

MUCHERO RABBITEYE BLUEBERRY INOKURUDZWA PAMUSORO PEFIGI YESystemic Mastocytosis UYE KURAPA Midostaurin.

Sarudza Nut BLACK WALNUT kana CHESTNUT?

Black Walnut ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seApigenin, Isoliquiritigenin, Myricetin, Quercetin, Kaempferol. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana-siyana dzebiochemical senge RAS-RAF Signaling, PI3K-AKT-MTOR Signaling uye MYC Signaling nevamwe. Black Walnut inokurudzirwa kuSystemic Mastocytosis kana ichienderera mberi kurapwa kwegomarara iri Midostaurin. Izvi zvinodaro nekuti Black Walnut inogadzirisa idzo nzira dzebiochemical dzakataurwa nesainzi kuti dzikurudzire mashandiro eMidostaurin.

Zvimwe zvezvinhu zvinoshanda kana bioactives muChestnut ndeye Apigenin, Isoliquiritigenin, Myricetin, Kaempferol, Luteolin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical sePI3K-AKT-MTOR Signaling, Oncogenic Cancer Epigenetics uye MYC Signaling nevamwe. Chestnut haikurudzirwe kuSystemic Mastocytosis kana ichienderera mberi kurapwa kwegomarara iri Midostaurin nekuti inogadzirisa idzo biochemical nzira dzinoita kuti kurapwa kwegomarara kurambe kana kusadaira.

BLACK WALNUT INAKURUDZIRWA PAMUSORO CHECHESTNUT YESystemic Mastocytosis UYE KURAPA Midostaurin.

Kune Vanhu Vane Genetic Risk yeCancer

Mubvunzo wakabvunzwa nevanhu vane genetic njodzi yeSystemic Mastocytosis kana nhoroondo yemhuri ndeye "Chii Chandinofanira Kudya Zvakasiyana Kubva Kare?" uye masarudzire avanofanira kuita zvekudya uye zvekuwedzera kuti vatarise njodzi dzechirwere. Sezvo kune njodzi yegomarara hapana chinogoneka maererano nekurapa - sarudzo dzezvekudya uye zvekuwedzera zvinove zvakakosha uye chimwe chezvinhu zvishoma zvingaite zvinogona kuitwa. Zvese zvinodyarwa-zvikafu hazvina kuenzana uye zvichibva pane zvakazivikanwa genetics uye nzira siginecha - sarudzo dzechikafu nekuwedzera dzinofanirwa kuve munhu.

Sarudza Vegetable CAULIFLOWER kana ARROWHEAD?

Vegetable Cauliflower ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seIsoliquiritigenin, Curcumin, Catechol, Vitamin C, Lupeol. Izvi zvinoshandiswa zvinosanganisa zvinoshandisa nzira dzakasiyana dzebiochemical sePI3K-AKT-MTOR Signaling, RAS-RAF Signaling, MAPK Signaling uye MYC Signaling nevamwe. Koliflower inokurudzirwa kune njodzi yeSystemic Mastocytosis kana yakabatana genetic njodzi iri CNOT3. Izvi zvinodaro nekuti Cauliflower inowedzera idzo nzira dzebiochemical dzinopokana nemadhiraivha ayo anosaina.

Zvimwe zvezvishandiso zvinoshandiswa kana bioactives mumuriwo Arrowhead ndeye Apigenin, Myricetin, Isoliquiritigenin, Kaempferol, Luteolin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seStem Cell Signaling uye Oncogenic Cancer Epigenetics nevamwe. Museve haukurudzirwe kana njodzi yeSystemic Mastocytosis kana yakabatana genetic njodzi iri CNOT3 nekuti inowedzera siginecha nzira dzayo.

VEGETABLE CAULIFLOWER INAKURUDZIRWA PAMUSORO ARROWHEAD YECNOT3 GENETIC RISK YECANCER.

Sarudza Muchero LEMON kana PUMMELO?

Muchero Lemon ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seIsoliquiritigenin, D-limonene, Luteolin, Linalool, Curcumin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana-siyana dzebiochemical seSuppressive Histone Methylation, RAS-RAF Signaling, PI3K-AKT-MTOR Kuratidzira uye MYC Kuratidzira nevamwe. Lemon inokurudzirwa kune njodzi yeSystemic Mastocytosis kana yakabatana genetic njodzi iri CNOT3. Izvi zvinodaro nekuti Lemon inowedzera idzo biochemical nzira dzinopokana nemadhiraivha emasaini ayo.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuchero Pummelo ndeye Apigenin, Quercetin, Isoliquiritigenin, Curcumin, Lycopene. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical sePI3K-AKT-MTOR Kuratidzira uye MYC Kuratidzira uye vamwe. Pummelo haikurudzirwe kana njodzi yeSystemic Mastocytosis kana yakabatana genetic njodzi iri CNOT3 nekuti inowedzera siginecha nzira dzayo.

MUCHERO LEMON INOKURUDZWA PAMUSORO PAMUSORO PAMUSORO PE CNOT3 GENETIC RISK OF CANCER.

Sarudza Nut BUTTERNUT kana EUROPEAN CHESTNUT?

Butternut ine zvakawanda zvinoshanda zvinosanganisa kana bioactives zvakaita seApigenin, Myricetin, Isoliquiritigenin, Kaempferol, Luteolin. Izvi zvinoshandiswa zvinoshandiswa zvinoshandisa nzira dzakasiyana dzebiochemical seJAK-STAT Signaling, RAS-RAF Signaling, MAPK Signaling uye MYC Signaling nevamwe. Butternut inokurudzirwa kune njodzi yeSystemic Mastocytosis kana yakabatana nejeneki njodzi iri CNOT3. Izvi zvinodaro nekuti Butternut inowedzera idzo nzira dzebiochemical dzinopesana nemadhiraivha ayo.

Zvimwe zvezvinhu zvinoshanda kana bioactives muEuropean Chestnut ndeye Apigenin, Quercetin, Myricetin, Isoliquiritigenin, Kaempferol. Izvi zvinoshandiswa zvinoshandiswa zvinoshandisa nzira dzakasiyana dzebiochemical seStem Cell Signaling uye Oncogenic Cancer Epigenetics nevamwe. European Chestnut haikurudzirwe kana njodzi yeSystemic Mastocytosis kana yakabatana genetic njodzi iri CNOT3 nekuti inowedzera siginecha nzira dzayo.

BUTTERNUT INOKURUKURWA PAMUSORO PAEUROPA CHESTNUT YECNOT3 GENETIC RISK YECANCER.

Mhedziso

Chikafu uye Zvekuwedzera zvakasarudzwa sarudzo dzakakosha dzegomarara seSystemic Mastocytosis. Systemic Mastocytosis varwere uye vanhu vane genetic-njodzi vanogara vaine mubvunzo uyu: "Ndezvipi zvekudya uye zvinovaka muviri zvinokurudzirwa kwandiri uye izvo zvisiri?" Pane chitendero chakajairika chinova fungidziro isiriyo yekuti zvese zvinodyarwa-zvikafu zvinogona kubatsira kana kwete asi zvisingakuvadze. Zvimwe zvekudya uye zvekuwedzera zvinogona kukanganisa marapirwo egomarara kana kusimudzira mamorekuru enzira yegomarara.

Kune marudzi akasiyana ezviratidzo zvegomarara seSystemic Mastocytosis, imwe neimwe iine bundu genetics ine mamwe ma genomic musiyano pamunhu wega wega. Kuwedzera kurapwa kwegomarara uye chemotherapy ine yakasarudzika nzira yekuita. Chikafu chega chega seBrussel Sprouts chine akasiyana bioactives muhuwandu hwakasiyana, izvo zvine chekuita pane akasiyana uye akasiyana seti e biochemical nzira. Tsanangudzo yekudya yakasarudzika ndeyakasarudzika chikafu kurudziro yegomarara chiratidzo, marapirwo, genetics, mararamiro uye zvimwe zvinhu. Sarudzo dzehutano hwemunhu hwegomarara dzinoda ruzivo rwegomarara biology, sainzi yechikafu uye kunzwisisa kweakasiyana chemotherapy marapirwo. Chekupedzisira kana paine shanduko yekurapa kana nyowani genomics inoonekwa - iyo inovaka muviri inoda kuongororwazve.

Iyo addon nutrition personalization solution inoita kuti sarudzo ive nyore uye inobvisa fungidziro yese mukupindura mubvunzo, "Ndezvipi zvekudya zvandinofanira kusarudza kana kusasarudzira Systemic Mastocytosis?". Iyo addon yakawanda-yekuranga timu inosanganisira varapi vegomarara, masayendisiti ekiriniki, mainjiniya esoftware uye masayendisiti edata.

References

• Aml Ohsu 2018
• Mhedzisiro ye isoliquiritigenin pamasero egomarara reovarian.
• Gallic acid indanone uye mangiferin xanthone zvinogadzirisa zvakasimba zve immunosuppressive anti-tumor zvinokonzerwa neMangifera indica L. bark mu MDA-MB231 masero ekenza yemazamu.
• Sulforaphane inokonzera epigenetic kudzvinyirirwa kwehTERT kutaura mukenza yemazamu cell mitsara.
• Kukura kwekukurudzira kwemasero emunhu pulmonary adenocarcinoma uye madiki epithelial masero emhepo ne beta-carotene kuburikidza ne activation ye cAMP, PKA, CREB uye ERK1/2.
• Geraniol, chikamu chezvirimwa zvakakosha oiri, inosimudzira masero egomarara revanhu ku5-Fluorouracil kurapwa.
• Functional lipidomics: Palmitic acid inokanganisa hepatocellular carcinoma kukura nekugadzirisa membrane fluidity uye glucose metabolism.
• D-Limonene inogadzirisa kuzvimba, oxidative kusagadzikana uye Ras-ERK nzira yekudzivisa murine ganda tumorigenesis.
• Kudzivirira mhedzisiro yebutyric acid, nicotinamide, calcium glucarate yoga kana musanganiswa panguva ye7, 12-dimethylbenz (a) anthracene induced mouse skin tumorigenesis kuburikidza nemodulation yeK-Ras-PI3K-AKTpathway uye yakabatana micro RNAs.