Zvokudya zveWaldenstrom Macroglobulinemia!

ziviso

Zvikafu zveWaldenstrom Macroglobulinemia zvinofanirwa kuve zvakasarudzika kune wega wega uye zvakare zvinofanirwa kuchinjika kana kenza kurapwa kana bundu genetic shanduko. Iyo yemunhu uye kugadzirisa kunofanirwa kufunga nezvese zvinoshanda zvinosanganiswa kana bioactives zviri muzvokudya zvakasiyana zvine chekuita negomarara biology, genetics, marapirwo, mararamiro uye zvido zvekudya. Saka nepo chikafu chiri chimwe chezvisarudzo zvakakosha zvemurwere wegomarara uye munhu ari panjodzi yegomarara - kusarudza chikafu chekudya harisi basa riri nyore.

Waldenstrom macroglobulinemia chirwere chisingawanzoitiki, chisingaperi chinokanganisa masero machena eropa (lymphocytes). Imhando ye-non-Hodgkin lymphoma. Inonziwo lymphoplasmacytic lymphoma. Ikenza yeropa isingawanzoitiki, inononoka kukura iyo inoratidzwa nekuvapo kwehuwandu hwemacroglobulin (immunoglobin M [IgM]. Iprotein yeM inokora ropa, ichikanganisa kuyerera kweropa kuburikidza netutsinga tuduku, mamiriro asingawanzoitiki. Waldenstrom macroglobulinemia inonzi hyper viscosity syndrome.Serum inonzi viscous serum dzimwe nguva inogona kukonzera misodzi mutsinga diki dzeropa, zvichiita kuti mhino, mazamu, kana kuti retina mumaziso abude ropa. uye kuvharisa masero eropa ajairika zvichikonzera kudzikira kushanda kwemasero matsvuku eropa, neutrophils nemaplatelet zvokonzera cytopenic conditions seanemia, neutropenia, uye thrombocytopenia. yeWaldenstrom macroglobulinemia inosanganisira kuneta, kupisa muviri, kurasikirwa nechido chekudya, kudikitira usiku, kushaya simba, kubuda ropa mumhino, kusaona zvakanaka, chiropa chakawedzera kana spleen uye kuzvimba lymph nodes. Chimwe chezvikonzero zvinokonzeresa zveWaldenstrom macroglobulinemia mu90% yevarwere vakaonekwa ndeyekuchinja kwejini MYD88. Mwero wemakore mashanu ekupona kwevarwere vakawanikwa vaine chirwere ichi 5% (American Cancer Society, 78). Marapirwo angasarudzwa eWaldenstrom macroglobulinemia anosanganisira plasmapheresis (plasma exchange), chemotherapy, immunotherapy, targeted therapy, radiation therapy uye stem cell kana bone marrow transplant. Pamusoro pezvo, chikafu chakakodzera (chikafu uye zvechisikigo zvekuwedzera) zvakaenderana nedanho regomarara uye mamiriro ekurapa anogona kuwedzera hutano hwevarwere.

Kune Waldenstrom Macroglobulinemia zvine basa here kuti miriwo, michero, nzungu, mhodzi munhu anodya chii?

Mubvunzo wakajairika wekudya unobvunzwa nevarwere vegomarara uye vanhu vari pa-genetic njodzi yegomarara ndeye - kumakonza akaita seWaldenstrom Macroglobulinemia zvine basa here kuti ndechipi chikafu chandinodya uye chandisingade? Kana kuti ndikatevera kudya-kwekudyara kunokwana kenza seWaldenstrom Macroglobulinemia?

Semuenzaniso zvine basa here kana muriwo weChicory Leaves uchidyiwa zvakanyanya kana uchienzaniswa neChando Squash? Zvinoita mutsauko here kana muchero Grapefruit inosarudzwa pane Pear? Zvakare kana sarudzo dzakafanana dzakaitirwa nzungu/mhodzi dzakaita seWalnut pamusoro peWalnut yekuJapan uye nemapumhu akaita seCowpea pamusoro peWhite Lupine. Uye kana izvo zvandinodya zvine basa - zvino munhu angaziva sei zvikafu zvinokurudzirwa kuWaldenstrom Macroglobulinemia uye ndiyo mhinduro imwechete kune wese ane chirwere chakafanana kana genetic ngozi?

Ehe! Zvokudya zvaunodya zvine chekuita neWaldenstrom Macroglobulinemia!

Mazano echikafu anogona kunge asina kufanana kune wese munhu uye anogona kuve akasiyana kunyangwe kune imwechete kuongororwa uye genetic njodzi.

Zvokudya zvose (miriwo, michero, nzungu, mhodzi, pulses, mafuta nezvimwewo) uye zvokudya zvinovaka muviri zvinoumbwa nezvinodarika imwe inoshanda mamolecular ingredient kana bio-actives muzvikamu zvakasiyana uye uwandu. Chinhu chimwe nechimwe chinoshanda chine nzira yakasarudzika yekuita - iyo inogona kuve activation kana inhibition yeakasiyana biochemical nzira. Zvikafu zvakangotaurwa uye zvekuwedzera izvo zvinokurudzirwa ndezviya zvisingakonzere kuwedzera kwemamorekuru anotyaira cancer asi anodzideredza. Zvikasadaro izvo zvikafu hazvifanirwe kukurudzirwa. Chikafu chine akawanda anoshanda zvinongedzo - saka kana uchiongorora chikafu uye zvekuwedzera iwe unofanirwa kufunga nezve mabatiro ezvese zvinoshanda zvinongedzo zvakapetwa kwete zvega.

Semuenzaniso Grapefruit ine zvinhu zvinoshanda Chlorogenic Acid, Ferulic Acid, Curcumin, Isoliquiritigenin, Delphinidin. Uye Pear ine zvinoshanda zvinosanganisa Chlorogenic Acid, Gallic Acid, Isoliquiritigenin, Curcumin, Genistein uye pamwe nevamwe.

Chikanganiso chinowanzoitwa pakusarudza nekusarudza chikafu chekudya cheWaldenstrom Macroglobulinemia - kuongorora chete zvakasarudzwa zvinoshandiswa zviri muzvokudya uye kufuratira zvimwe. Nekuti zvakasiyana-siyana zvinoshanda zviri muzvokudya zvinogona kuva nemhedzisiro inopikisa kune vatyairi vegomarara - haugone kutora cherry inoshanda mukudya uye ma supplements ekuita sarudzo yehutano yeWaldenstrom Macroglobulinemia.

HONGU – ZVOKUSARUDZA ZVOKUDYA ZVINOKOSHA NEGONSA. ZVISARUDZO ZVOKUDYA ZVINOFANIRA KUFUNGA ZVINHU ZVINHU ZVINHU ZVINOSHANDA PACHIDYA.

Unyanzvi Hunodiwa Kuti Kuve Nekudya Kwemunhu KweWaldenstrom Macroglobulinemia?

Kudya kwakasarudzika kwegomarara seWaldenstrom Macroglobulinemia ine chikafu chinokurudzirwa / ma supplements; zvisingakurudzirwe chikafu / ma supplements ane semuenzaniso mabikirwo anotungamira kushandiswa kwezvikafu zvinokurudzirwa. Muenzaniso wekudya kwakasiyana-siyana unogona kuonekwa pane izvi batanidzo.

Kufunga kuti ndezvipi zvekudya zvinokurudzirwa kana kwete zvakaomesesa, zvinoda hunyanzvi muWaldenstrom Macroglobulinemia biology, sainzi yechikafu, genetics, biochemistry pamwe nekunzwisisa kwakanaka kwemashandiro anoita marapirwo egomarara pamwe nekusagadzikana kwakabatana uko kurapwa kwaigona kumira kushanda.

ZVINONYANYA ZVINONYANYA ZVINODIWA KUTI ZVINOVAKA ZVINOVAKA MUNHU ZVINHU ZVINHU ZVINOITA: CANCER BIOLOGY, FOOD SCIENCE, KURAPA MAKANZA UYE GENETICS.

Hunhu hwegomarara seWaldenstrom Macroglobulinemia

Ese magomarara seWaldenstrom Macroglobulinemia anogona kuratidzirwa neyakasiyana seti yebiochemical nzira - iyo siginecha nzira dzeWaldenstrom Macroglobulinemia. Biochemical pathways seNFKB Signaling, Chromatin Remodeling, Growth Factor Signaling, MAPK Signaling chikamu chetsanangudzo yeSiginecha yeWaldenstrom Macroglobulinemia. Kenza yemunhu wega genetics inogona kuve yakasiyana uye nekudaro siginicha yavo yegomarara inogona kuve yakasarudzika.

Kurapa kunoshanda kuWaldenstrom Macroglobulinemia kunoda kuziva nezve siginecha yebiochemical nzira kune wese murwere wegomarara uye munhu ari panjodzi yemajini. Saka marapirwo akasiyana ane maitiro akasiyana ezviito anoshanda kune varwere vakasiyana. Saizvozvo uye nekuda kwezvikonzero zvakafanana zvekudya uye zvekuwedzera zvinoda kuitirwa munhu wega wega. Saka zvimwe zvekudya uye zvekuwedzera zvinokurudzirwa kuWaldenstrom Macroglobulinemia kana uchitora kurapwa kenza Ibrutinib, uye zvimwe zvekudya uye zvekuwedzera hazvikurudzirwe.

Sources like cBioPortal uye vamwe vazhinji vanopa mumiriri wehuwandu hwevarwere data risingazivikanwe kubva kukiriniki miedzo yezvese zviratidzo zvegomarara. Iyi dhata ine yekiriniki yekuongorora yeruzivo senge sampuli saizi / nhamba yevarwere, mapoka ezera, murume kana mukadzi, dzinza, marapirwo, bundu saiti uye chero genetic mutations.

ARID1A, IGF1R, MAP3K1 uye MYD88 ndiwo mazita epamusoro akashumwa majini eWaldenstrom Macroglobulinemia. ARID1A inoshumwa mu100.0% yevanomiririra varwere mukati meyese miedzo yekiriniki. Uye IGF1R inoshumwa mu100.0%. Iyo yakasanganiswa yehuwandu hwevarwere data inovhara mazera kubva kusvika . 100.0% yedata revarwere vanoonekwa sevarume. Iyo Waldenstrom Macroglobulinemia biology pamwe chete neiyo genetics yakashumwa pamwe chete inotsanangura huwandu hwevanhu vanomiririrwa nemasaini ebiochemical nzira dzegomarara iri. Kana iyo yega cancer tumor genetics kana majini anokonzera njodzi achizivikanwawo saka izvo zvinofanirwa kushandiswawo kune hutano hwemunhu.

ZVAKASARUDZA KUDYA ZVINODYA ZVINOFANIRA KUFANIRA NEMUNHU WEMUNHU WEMUNHU WEMUNHU WEGONSI.

Chikafu uye Zvekuwedzera zveWaldenstrom Macroglobulinemia

Kune Varwere veCancer

Varwere vegomarara vari pakurapa kana pakuchengeta palliative vanofanira kuita sarudzo pazvekudya uye zvekuwedzera - zvemacalorie anodiwa ekudya, kubata chero mhedzisiro yekurapa uyezve nekugadzirisa kenza. Zvese zvinodyarwa-zvikafu hazvina kuenzana uye kusarudza uye kuisa pamberi pezvikafu zvakagadzirirwa munhu uye zvakagadzirirwa kuenderera mberi kurapwa kwegomarara kwakakosha uye kwakaoma. Heano mimwe mienzaniso inopa nhungamiro yekuita sarudzo dzekudya.

Sarudza Vegetable CHICORY LEAves kana WINTER SQUASH?

Vegetable Chicory Mashizha ane akawanda anoshanda zvinhu kana bioactives akadai Chlorogenic Acid, Gallic Acid, Isoliquiritigenin, Curcumin, Apigenin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seNFKB Signaling uye nevamwe. Chicory Leaves inokurudzirwa kuWaldenstrom Macroglobulinemia apo chirwere chegomarara chiri kuramba chiri Ibrutinib. Izvi zvinodaro nekuti Chicory Mashizha anogadzirisa idzo nzira dzebiochemical dzakataurwa nesainzi kuti dzigonese mhedzisiro yeIbrutinib.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuriwo Winter Squash ndeye Chlorogenic Acid, Protocatechuic Acid, Isoliquiritigenin, Apigenin, Curcumin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seNFKB Signaling uye nevamwe. Nguva yechando Squash haikurudzirwe kuWaldenstrom Macroglobulinemia kana chirwere chegomarara chiri kuramba chiri Ibrutinib nekuti chinogadzirisa nzira dziye dzebiochemical dzinoita kuti kurapwa kwegomarara kumire kana kusadaira.

MURIWO CHICORY MASHIVI ANOKURUKURWA PAMUSORO PEZVAKA SQUASH YEWaldenstrom Macroglobulinemia UYE KURAPA Ibrutinib.

Sarudza Chibereko PEAR kana GRAPEFRUIT?

Fruit Pear ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seChlorogenic Acid, Gallic Acid, Isoliquiritigenin, Curcumin, Genistein. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seNFKB Signaling nevamwe. Pear inokurudzirwa kuWaldenstrom Macroglobulinemia apo chirwere chegomarara chiri kuramba chiri Ibrutinib. Izvi zvinodaro nekuti Pear inogadzirisa idzo nzira dzebiochemical dzakataurwa nesainzi kuti dzikurudzire maitiro eIbrutinib.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuchero Grapefruit ndeye Chlorogenic Acid, Ferulic Acid, Curcumin, Isoliquiritigenin, Delphinidin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seNFKB Signaling uye nevamwe. Grapefruit haikurudzirwe kuWaldenstrom Macroglobulinemia kana kurapwa kwegomarara kuri kuramba kuchiitwa Ibrutinib nekuti inogadzirisa idzo biochemical nzira dzinoita kuti kurapwa kwegomarara kurambe kana kusadaira.

FRUIT PEAR INOKURUDZWA PAMUSORO PERAPEFRUIT YEWaldenstrom Macroglobulinemia UYE KURAPA Ibrutinib.

Sarudza Nut WALNUT kana JAPANESE WALNUT?

Walnut ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seCarvacrol, Chlorogenic Acid, Protocatechuic Acid, Curcumin, Isoliquiritigenin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seNFKB Signaling uye nevamwe. Walnut inokurudzirwa kuWaldenstrom Macroglobulinemia apo chirwere chegomarara chiri kuramba chiri Ibrutinib. Izvi zvinodaro nekuti Walnut inogadzirisa idzo nzira dzebiochemical dzakataurwa nesainzi kuti dzikurudzire maitiro eIbrutinib.

Zvimwe zvezvinhu zvinoshanda kana bioactive muJapan Walnut ndeye Chlorogenic Acid, Protocatechuic Acid, Apigenin, Curcumin, Isoliquiritigenin. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seNFKB Signaling uye nevamwe. Japanese Walnut haikurudzirwe kuWaldenstrom Macroglobulinemia kana ichiramba ichirapwa kenza iri Ibrutinib nekuti inogadzirisa idzo biochemical nzira dzinoita kuti kurapwa kwegomarara risarambe kana kusadaira.

WALNUT INOKURUDZIRWA PAMUSORO PAWALNUT YEJAPANESE YEWaldenstrom Macroglobulinemia UYE KURAPA Ibrutinib.

Kune Vanhu Vane Genetic Risk yeCancer

Mubvunzo wakabvunzwa nevanhu vane genetic risk yeWaldenstrom Macroglobulinemia kana nhoroondo yemhuri ndewekuti "Chii Chandinofanira Kudya Zvakasiyana Kubva Kare?" uye masarudzire avanofanira kuita zvekudya uye zvekuwedzera kuti vatarise njodzi dzechirwere. Sezvo kune njodzi yegomarara hapana chinogoneka maererano nekurapa - sarudzo dzezvekudya uye zvekuwedzera zvinove zvakakosha uye chimwe chezvinhu zvishoma zvingaite zvinogona kuitwa. Zvese zvinodyarwa-zvikafu hazvina kuenzana uye zvichibva pane zvakazivikanwa genetics uye nzira siginecha - sarudzo dzechikafu nekuwedzera dzinofanirwa kuve munhu.

Sarudza Vegetable GIANT BUTTERBUR kana MUSTARD SPINACH?

Vegetable Giant Butterbur ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seCurcumin, Apigenin, Lupeol, Daidzein, Lycopene. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical seSero Cycle, P53 Signaling, MAPK Signaling uye MYC Signaling nevamwe. Giant Butterbur inokurudzirwa kune njodzi yeWaldenstrom Macroglobulinemia kana njodzi yemajini yakabatana iri ARID1A. Izvi zvinodaro nekuti Giant Butterbur inowedzera idzo biochemical nzira dzinopokana nemadhiraivha emasaini ayo.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuriwo Mustard Sipinachi ndeye Curcumin, Apigenin, Lupeol, Daidzein, Lycopene. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seEpithelial kuenda kuMesenchymal Transition, WNT Beta Catenin Signaling uye NFKB Signaling nevamwe. Mustard Sipinachi haikurudzirwe kana njodzi yeWaldenstrom Macroglobulinemia kana yakabatana genetic njodzi iri ARID1A nekuti inowedzera siginecha nzira dzayo.

MURIWO MURUME BUTTERBUR ANOKURUKURIRWA PAMUSORO PEMUSTARD SPINACH KUTI ARID1A GENETIC RISK YECANCER.

Sarudza Muchero JAVA PLUM kana PUMMELO?

Chibereko Java Plum ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seCurcumin, Apigenin, Lupeol, Daidzein, Lycopene. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical seSero Cycle, P53 Signaling, MAPK Signaling uye MYC Signaling nevamwe. Java Plum inokurudzirwa kune njodzi yeWaldenstrom Macroglobulinemia kana njodzi yemajini yakabatana iri ARID1A. Izvi zvinodaro nekuti Java Plum inowedzera idzo biochemical nzira dzinopokana nemadhiraivha emasaini ayo.

Zvimwe zvezvinhu zvinoshanda kana bioactives mumuchero Pummelo ndeye Curcumin, Apigenin, Lupeol, Daidzein, Lycopene. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana dzebiochemical seEpithelial kuenda kuMesenchymal Transition uye WNT Beta Catenin Signaling nevamwe. Pummelo haikurudzirwe kana njodzi yeWaldenstrom Macroglobulinemia kana yakabatana genetic njodzi iri ARID1A nekuti inowedzera siginecha nzira dzayo.

FRUIT JAVA PLUM INAKURUDZIRWA PAMUSORO PEPUMMELO YEARID1A GENETIC RISK OF CANCER.

Sarudza Nut BUTTERNUT kana FLEXSEED?

Butternut ine zvakawanda zvinoshanda zvinosanganisa kana bioactives seCurcumin, Apigenin, Lupeol, Daidzein, Lycopene. Izvi zvinoshanda zvinosanganisa nzira dzakasiyana siyana dzebiochemical seSero Cycle, P53 Signaling, MAPK Signaling uye MYC Signaling nevamwe. Butternut inokurudzirwa kune njodzi yeWaldenstrom Macroglobulinemia kana njodzi yemajini yakabatana iri ARID1A. Izvi zvinodaro nekuti Butternut inowedzera idzo nzira dzebiochemical dzinopesana nemadhiraivha ayo.

Zvimwe zvezvinhu zvinoshanda kana bioactives muFlaxseed ndeye Curcumin, Apigenin, Lupeol, Daidzein, Beta-sitosterol. Izvi zvinoshandiswa zvinoshandiswa zvinoshandisa nzira dzakasiyana dzebiochemical seMAPK Signaling, Epithelial kuenda kuMesenchymal Transition, WNT Beta Catenin Signaling uye PI3K-AKT-MTOR Signaling nevamwe. Flaxseed haikurudzirwe kana njodzi yeWaldenstrom Macroglobulinemia kana yakabatana genetic njodzi iri ARID1A nekuti inowedzera siginecha nzira dzayo.

BUTTERNUT INOKURUDZIRWA PAMUSORO PEFLEXSEED YEARID1A GENETIC RISK YECANCER.

Mhedziso

Zvokudya uye Zvekuwedzera zvakasarudzwa sarudzo dzakakosha dzegomarara seWaldenstrom Macroglobulinemia. Waldenstrom Macroglobulinemia varwere uye vanhu vane genetic-njodzi vanogara vaine mubvunzo uyu: "Ndezvipi zvekudya uye zvinovaka muviri zvinokurudzirwa ini uye izvo zvisiri?" Pane chitendero chakajairika chinova fungidziro isiriyo yekuti zvese zvinodyarwa-zvikafu zvinogona kubatsira kana kwete asi zvisingakuvadze. Zvimwe zvekudya uye zvekuwedzera zvinogona kukanganisa marapirwo egomarara kana kusimudzira mamorekuru enzira yegomarara.

Kune marudzi akasiyana ezviratidzo zvegomarara seWaldenstrom Macroglobulinemia, imwe neimwe iine bundu genetics ine mamwe ma genomic musiyano pamunhu wega wega. Kuwedzera kurapwa kwegomarara uye chemotherapy ine yakasarudzika nzira yekuita. Chikafu chega chega seChicory Mashizha chine mabioactive akasiyana muhuwandu hwakasiyana, izvo zvine chekuita neakasiyana uye akasiyana seti yebiochemical nzira. Tsanangudzo yekudya yakasarudzika ndeyakasarudzika chikafu kurudziro yegomarara chiratidzo, marapirwo, genetics, mararamiro uye zvimwe zvinhu. Sarudzo dzehutano hwemunhu hwegomarara dzinoda ruzivo rwegomarara biology, sainzi yechikafu uye kunzwisisa kweakasiyana chemotherapy marapirwo. Chekupedzisira kana paine shanduko yekurapa kana nyowani genomics inoonekwa - iyo inovaka muviri inoda kuongororwazve.

Iyo addon nutrition personalization solution inoita kuti sarudzo ive nyore uye inobvisa zvese zvekufungidzira mukupindura mubvunzo, "Ndezvipi zvekudya zvandinofanira kusarudza kana kusasarudzira Waldenstrom Macroglobulinemia?". Iyo addon yakawanda-yekuranga timu inosanganisira varapi vegomarara, masayendisiti ekiriniki, mainjiniya esoftware uye masayendisiti edata.

References

• Msk Impact 2017
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• Chlorogenic-induced inhibition yeasiri-diki cancer maseru anoitika kuburikidza nemutemo we histone deacetylase 6.
• Curcumin inhibisa kukura kuburikidza neWnt / β-catenin nzira mune isiri-diki-sero kenza yemapapu maseru.
• Paederia foetida induces anticancer chiitiko nekugadzirisa chromatin modification enzymes uye kushandura pro-inflammatory cytokine gene kutaura mumunhu masero ekenza yeprostate.
• Betulinic Acid Inoderedza Breast Cancer Metastasis neTargeting GRP78-Mediated Glycolysis uye ER Stress Apoptotic Pathway.
• Vitamin C inowedzera epigenetic modifications inokonzerwa ne5-azacytidine uye cell cycle kusungwa muhepatocellular carcinoma cell lines HLE uye Huh7.
• https://emedicine.medscape.com/article/207097-overview
• https://my.clevelandclinic.org/health/diseases/17951-waldenstrom-macroglobulinemia
• https://www.mayoclinic.org/diseases-conditions/waldenstrom-macroglobulinemia/symptoms-causes/syc- 20359967