Mea'ai mo le Fa'ama'i Erdheim Chester!

faʻatomuaga

Mea'ai mo Erdheim Chester Fa'ama'i e tatau ona fa'apitoa mo tagata ta'ito'atasi ma e tatau fo'i ona fetuutuunai pe a o'o i togafitiga o le kanesa po'o suiga o le tumo. O le fa'avasegaina ma le fetuutuuna'iga e tatau ona mafaufau i mea aoga uma po'o meaola fa'aola o lo'o i totonu o mea'ai eseese e fa'atatau i le biology o le kanesa, genetics, togafitiga, tulaga o le olaga ma mea e fiafia i ai. O le mea lea e ui o mea'ai o se tasi lea o filifiliga taua tele mo se tagata ma'i kanesa ma tagata ta'ito'atasi o lo'o a'afia i le kanesa e fai - o le auala e filifili ai mea'ai e 'ai e le o se galuega faigofie.

O le Fa'ama'i Erdheim-Chester (ECD) e seasea maua, e le o Langerhans cell histiocytosis, e masani ona ta'ua o se kanesa, ma lona mafua'aga o lo'o su'esu'eina ae e le masani ona ta'ua o se gafa po'o se kenera. Fa'ailogaina i fa'ailoga fa'apitoa e pei o le tiga o ponaivi ma fa'aaliga o le neura, o su'esu'ega ECD e aofia ai le fa'afefiloi o metotia fa'a leitio, e aofia ai le CT ma le fai'ai MRI, ma fa'ata'ita'iga mae'ae'a. Fuafuaga mo togafitiga mo le Erdheim-Chester Disease o loʻo faʻaauau pea ona faʻaleleia, faʻatasi ai ma faʻamatalaga faʻafouina e mafai ona maua e ala i luga ole UpToDate ma le Erdheim-Chester Disease Global Alliance. O le ECD e masani ona aofia ai totoga e pei o mama ma le fai'ai, ma o le leitio e taua tele mo le su'esu'eina ma le mataituina o faama'i. Fa'avasegaina i lalo ole faiga ole ICD-10, o lo'o fa'amalamalamaina le pulega a le ECD e ala i iloiloga ma su'esu'ega fa'ata'ita'iga, e fa'ailoa ai le taua o su'esu'ega faifaipea ma fa'alauiloa ile fo'ia o lenei fa'ama'i lavelave.

Mo Erdheim Chester Disease e afaina po o a fualaau faisua, fualaau aina, nati, fatu e 'ai e se tasi?

O se fesili masani o mea'ai e fesiligia e tagata ma'i kanesa ma tagata ta'ito'atasi e ono maua i le kanesa - mo kanesa e pei o le Erdheim Chester Disease e afaina po'o a mea'ai ou te 'ai ae leai? Pe afai ou te mulimulita'i i mea'ai e fa'atatau i la'au ua lava lea mo le kanesa pei ole Erdheim Chester Disease?

Mo se fa'ata'ita'iga e afaina pe a sili atu le taumafaina o fuala'au eggplant pe a fa'atusatusa i le Chayote? E iai se eseesega pe afai e sili atu le fua o le Sugar Apple nai lo le Arctic Blackberry? E fa'apea fo'i pe a fai filifiliga fa'apena mo nati/ fatu e pei o le Walnut Uliuli i luga o le Macadamia Nut ma mo pulus pei o Green Bean i luga o Catjang Pea. Ae afai e afaina mea ou te 'ai - e faapefea la ona iloa e se tasi mea'ai e fautuaina mo le Erdheim Chester Disease ma pe tutusa ea le tali mo tagata uma e tutusa le su'esu'ega po'o le fa'alavelave fa'aletagata?

Ioe! Mea'ai e te 'ai e afaina mo Erdheim Chester Disease!

O fautuaga o mea'ai atonu e le tutusa mo tagata uma ma e mafai ona eseese e tusa lava pe tutusa le su'esu'ega ma fa'alavelave fa'aletagata.

Mea'ai uma (fualaau faisua, fualaau 'aina, nati, fatu, fatu, suau'u ma isi mea'ai) ma mea'ai fa'aopoopo o lo'o faia i le sili atu ma le tasi le mole mole ga'o po'o bio-actives i vaega eseese ma aofa'i. O mea aoga ta'itasi o lo'o i ai se faiga fa'apitoa e fa'atino ai - e mafai ona fa'agaoioia pe fa'alavelaveina ala fa'aolaola eseese. O mea'ai ma mea'ai fa'aopoopo o lo'o fautuaina e le fa'atupuina le fa'atuputeleina o mea'ai mole mole o le kanesa ae fa'aitiitia. A leai o na meaai e le tatau ona fautuaina. O mea'ai e aofia ai le tele o mea aoga - o le mea lea pe a iloiloina mea'ai ma mea'ai faaopoopo e tatau ona e mafaufau i le a'afiaga o mea aoga uma fa'aopoopo nai lo le ta'ito'atasi.

Mo se faʻataʻitaʻiga Sugar Apple o loʻo i ai mea aoga Myricetin, Lycopene, Pelargonidin, Curcumin, Cinnamaldehyde. Ma Arctic Blackberry o loʻo i ai mea aoga Ellagic Acid, Lycopene, Curcumin, Quercetin, Cinnamaldehyde ma atonu o isi.

O se mea sese masani e fai pe a filifili ma filifili mea'ai e 'ai mo le Erdheim Chester Disease - o le iloiloina na'o mea aoga ua filifilia o lo'o i totonu o mea'ai ae le amana'ia isi mea'ai. Ona o mea aoga eseese o lo'o i totonu o mea'ai e ono iai ni a'afiaga fa'afeagai i aveta'avale o le kanesa - e le mafai ona e filifilia mea aoga i mea'ai ma mea fa'aopoopo mo le faia o se filifiliga tau mea'ai mo le Erdheim Chester Disease.

IOE – FILIFILIGA O MEAAI E TAUA MO LE KANESA. E TATAU ONA MAFAUFAU I FILIFILIGA FA'ANUI UMA O MEA UA FAI O MEAAI.

Tomai e Manaomia mo Mea'ai Fa'apitoa mo Erdheim Chester Disease?

Mea'ai fa'apitoa mo kanesa e pei ole Erdheim Chester Disease e aofia ai mea'ai / fa'aopoopoga fautuaina; mea'ai e le fautuaina / fa'aopoopoga fa'atasi ai ma fa'ata'ita'iga fua e fa'amuamua le fa'aogaina o mea'ai fautuaina. O se faʻataʻitaʻiga o meaʻai faʻapitoa e mafai ona vaʻaia i lenei mea fesoʻotaʻiga.

O le filifili po o fea mea'ai e fautuaina pe leai e matua faigata lava, e mana'omia ai le poto i le Erdheim Chester Disease biology, food science, genetics, biochemistry fa'atasi ai ma le malamalama lelei i le auala e galue ai togafitiga o le kanesa ma fa'afitauli fa'aletonu e ono taofia ai le aoga.

FA'ATA'ITA'I FA'AMANATU FA'AMATALAGA E MANA'OINA MO FA'A'I'I FA'A'AI MO LE KANESA E IA: KANESA BIOLOGY, SCIENCE FOOD, TAGA'IGA KANESA MA GENETICS.

O uiga o kanesa e pei ole Erdheim Chester Disease

O kanesa uma e pei o le Erdheim Chester Disease e mafai ona fa'ailogaina i se seti tulaga ese o ala fa'aola kemikolo - o ala saini a le Erdheim Chester Disease. O auala faʻaola e pei o le RAS-RAF Signaling, MAPK Signaling, Cytoskeletal Dynamics, Angiogenesis o se vaega o le faʻamatalaga saini o Erdheim Chester Disease. E mafai ona 'ese'ese le kenera o le kanesa o tagata ta'ito'atasi ma o lea e mafai ai ona tulaga ese a latou saini fa'apitoa ole kanesa.

O togafitiga e aoga mo le Erdheim Chester Disease e mana'omia le iloa lelei o ala fa'aola biochemical e feso'ota'i mo tagata ma'i kanesa ta'ito'atasi ma tagata ta'ito'atasi o lo'o a'afia i gasegase. O lea la o togafitiga eseese ma auala eseese o gaioiga e aoga mo gasegase eseese. E fa'apena fo'i ma mo mafua'aga lava e tasi e mana'omia ai le fa'apitoa o mea'ai ma mea'ai mo tagata ta'ito'atasi. O le mea lea e fautuaina ai nisi o mea'ai ma mea'ai mo le Erdheim Chester Disease pe a fai togafitiga o le kanesa Vemurafenib, ma o nisi mea'ai ma mea'ai faaopoopo e le fautuaina.

Punavai pei cBioPortal ma le tele o isi o lo'o tu'uina mai ai fa'amatalaga o tagata ma'i e le o ta'ua mai fa'ata'ita'iga mo fa'ailoga uma o le kanesa. O nei fa'amaumauga e aofia ai fa'amatalaga su'esu'ega fa'ata'ita'i fa'ata'ita'i e pei o le lapo'a / numera o tagata mama'i, vaitausaga, itupa, ituaiga, togafitiga, nofoaga tumo ma so'o se suiga fa'aletagata.

MAP2K1, ARAF, ARID5B, BRAF ma MYCN o le pito i luga o lo'o lipotia genes mo Erdheim Chester Disease. MAP2K1 o loʻo lipotia i le 25.0% o sui maʻi i faʻataʻitaʻiga uma. Ma o le ARAF o loʻo lipotia i le 12.5%. O fa'amaumauga tu'ufa'atasi o tagata ma'i e aofia ai tausaga mai le . 61.5% o faʻamaumauga o maʻi ua faʻamaonia o tane. Ole biology ole Erdheim Chester Disease fa'atasi ai ma genetics ua lipotia fa'atasi e fa'amatala ai le faitau aofa'i o ala fa'aola biochemical saini mo lenei kanesa. Afai o le tagata ta'ito'atasi o le kanesa tumo genetics po'o genes o lo'o saofagā i le lamatiaga o lo'o iloa fo'i ona tatau lea ona fa'aoga mo le fa'avasegaina o mea'ai.

O FILIFILIGA FA'A'I MEA'AI E TATAU ONA FA'A'OGA MA LE SAINI KANAGA A TA'ATatasi.

Mea'ai ma Mea'ai mo le Fa'ama'i Erdheim Chester

Mo Ma'i Kanesa

E mana'omia e tagata mama'i o le kanesa i togafitiga po'o le tausiga fa'alesoifua maloloina ona fai fa'ai'uga i mea'ai ma mea fa'aopoopo - mo mea'ai e mana'omia, mo le puleaina o so'o se a'afiaga o togafitiga ma fa'apea fo'i le fa'aleleia atili o le puleaina o le kanesa. O mea'ai uma e fa'atatau i la'au e le tutusa ma e taua ma lavelave le filifilia ma le fa'amuamua o mea'ai e fa'apitoa ma fa'apitoa mo togafitiga fa'aauau. O nisi nei o fa'ata'ita'iga o lo'o tu'uina atu ai ta'iala mo le faia o filifiliga o mea'ai.

Filifili Fualaau EGGPLANT poʻo CHAYOTE?

Fualaau eggplant o loʻo i ai le tele o mea aoga poʻo meaola faʻapitoa e pei ole Myricetin, Isorhamnetin, Gallic Acid, Curcumin, Quercetin. O nei mea aoga e faʻaogaina auala eseese o meaola e pei o le WNT Beta Catenin Signaling, RAS-RAF Signaling ma MAPK Signaling ma isi. E fautuaina le eggplant mo le Erdheim Chester Disease pe a fai le togafitiga o le kanesa o le Vemurafenib. E mafua ona ua suia e le Eggplant ia auala fa'aola fa'asaienisi ua lipotia fa'asaienitisi e fa'ailoa ai le aafiaga ole Vemurafenib.

O nisi o mea aoga poʻo meaola olaola i fualaau faisua Chayote o Myricetin, Pelargonidin, Curcumin, Cinnamaldehyde, Isoliquiritigenin. O nei mea aoga e faʻaogaina auala eseese o meaola e pei o le WNT Beta Catenin Signaling ma le MAPK Signaling ma isi. E le fautuaina le Chayote mo le Erdheim Chester Disease pe a fai o togafitiga o le kanesa o le Vemurafenib aua e suia ai na auala biochemical e mafai ai ona tetee le kanesa pe itiiti le tali atu.

E FAUTUA LE FAI FAI FA'AALAAU I LE CHAYOTE MO Fa'ama'i Erdheim Chester MA TOFOAGA Vemurafenib.

Filifili Fualaau ARCTIC BLACKBERRY poʻo SUGAR APPLE?

Fua Arctic Blackberry o loʻo i ai le tele o mea aoga poʻo meaola faʻapitoa e pei ole Ellagic Acid, Lycopene, Curcumin, Quercetin, Cinnamaldehyde. O nei mea aoga e faʻaogaina auala eseese o meaola e pei o le WNT Beta Catenin Signaling, RAS-RAF Signaling ma MAPK Signaling ma isi. O le Arctic Blackberry e fautuaina mo le Erdheim Chester Disease pe a faʻaauau togafitiga o le kanesa o Vemurafenib. E mafua ona ua suia e Arctic Blackberry ia auala faʻaola faʻasaienisi ua lipotia faʻasaienisi e faʻaalia ai le aafiaga o Vemurafenib.

O nisi o mea aoga poʻo meaola faʻaola i totonu o fualaau suamalie Sugar Apple o Myricetin, Lycopene, Pelargonidin, Curcumin, Cinnamaldehyde. O nei mea aoga e fa'aogaina auala fa'aola fa'aola e pei o le WNT Beta Catenin Signaling ma isi. E le fautuaina le Sugar Apple mo le Erdheim Chester Disease pe a fai le togafitiga o le kanesa o le Vemurafenib aua e suia ai na auala biochemical e mafai ai ona puipuia le kanesa togafitiga pe itiiti le tali atu.

FRUIT ARCTIC BLACKBERRY E FAUTUAINA IA APOLI SUKA MO Erdheim Chester Fa'ama'i MA TOGAGA ​​Vemurafenib.

Filifili nati BLACK WALNUT po'o MACADAMIA NUT?

Black Walnut o loʻo i ai le tele o mea aoga poʻo meaola faʻapitoa e pei ole Myricetin, Ellagic Acid, Pelargonidin, Gallic Acid, Curcumin. O nei mea aoga e fa'aogaina auala fa'aola fa'aola e pei o le RAS-RAF Signaling ma le MAPK Signaling ma isi. Ua fautuaina le Black Walnut mo le fa'ama'i Erdheim Chester pe'a fa'aauau le togafitiga o le kanesa o Vemurafenib. E mafua ona ua suia e le Black Walnut ia auala faʻaola faʻasaienisi ua lipotia faʻasaienisi e faʻaalia ai le aafiaga o Vemurafenib.

O nisi o mea aoga poʻo meaola faʻapitoa i Macadamia Nut o Myricetin, Pelargonidin, Curcumin, Cinnamaldehyde, Isoliquiritigenin. O nei mea aoga e faʻaogaina auala eseese o meaola e pei o le WNT Beta Catenin Signaling ma le MAPK Signaling ma isi. E le fautuaina le Macadamia Nut mo le Erdheim Chester Disease pe a fai le togafitiga o le kanesa o le Vemurafenib aua e suia ai na auala biochemical lea e mafai ai ona tetee le kanesa pe itiiti le tali atu.

E FAATUATUA LE NATI BLACK I LE MACADAMIA NUT MO ERDheim Chester Disease MA TOGOTAGA Vemurafenib.

Mo Tagata ta'ito'atasi e iai le lamatiaga o le kanesa

O le fesili na fesiligia e tagata taʻitoʻatasi o loʻo i ai le lamatiaga o le Erdheim Chester Disease poʻo le talafaasolopito o aiga o le "O le a le mea e tatau ona ou 'ai ese mai le taimi muamua?" ma le auala e tatau ona latou filifilia ai meaai ma mea faaopoopo e pulea ai tulaga lamatia o le faamai. Talu ai mo le lamatiaga o le kanesa e leai se mea e mafai ona faia i le tulaga o togafitiga - o filifiliga o meaʻai ma mea faaopoopo e taua tele ma o se tasi o mea laiti e mafai ona fai. O mea'ai uma e fa'atatau i la'au e le tutusa ma fa'avae ile kenera ma saini ala - o filifiliga o mea'ai ma mea'ai e tatau ona fa'apitoa.

Filifili fualaau faisua GIANT BUTTERBUR poʻo GARLAND CHRYSANTHEMUM?

Vegetable Giant Butterbur o loʻo i ai le tele o mea aoga poʻo meaola faʻapitoa e pei ole Apigenin, Curcumin, Myricetin, Lycopene, Lupeol. O nei mea aoga e faʻaogaina auala eseese o meaola e pei o Angiogenesis, RAS-RAF Signaling, Cell Cycle ma le PI3K-AKT-MTOR Signaling ma isi. Giant Butterbur e fautuaina mo le lamatiaga o le Erdheim Chester Disease pe a o'o i le gasegase o le ARAF. E mafua ona o Giant Butterbur ua faʻateleina na auala biochemical e faʻafefe ai le saini avetaavale.

O nisi o mea aoga poʻo meaola olaola i fualaau faisua Garland Chrysanthemum o Apigenin, Curcumin, Myricetin, Lupeol, Daidzein. O nei mea aoga e faʻaogaina auala eseese o meaola e pei o le WNT Beta Catenin Signaling ma le MAPK Signaling ma isi. E le fautuaina le Garland Chrysanthemum pe a a'afia i le Erdheim Chester Disease pe a o'o iai fa'afitauli fa'aletagata ole ARAF aua e fa'ateleina ai le saini ala o ia.

FAATUATUA LE GARLAND CHRYSANTHEMUM MO LE ARAF GENETIC RISET OF CANCER.

Filifili Fua NANCE po'o PUMMELO?

Fua Nance o loʻo iai le tele o mea aoga poʻo meaola faʻapitoa e pei ole Apigenin, Curcumin, Myricetin, Lupeol, Daidzein. O nei mea aoga e faʻaogaina auala eseese o meaola e pei o Angiogenesis, RAS-RAF Signaling, Cell Cycle ma le PI3K-AKT-MTOR Signaling ma isi. E fautuaina le Nance mo le ono maua i le Erdheim Chester Disease pe a o'o iai le fa'alavelave fa'aletagata ole ARAF. E mafua ona ua fa'ateleina e Nance ia auala fa'aola kemikolo e fa'afete'ena'i ai le saini fa'ata'avale.

O nisi o mea aoga poʻo mea olaola i totonu o fualaau aina Pummelo o Apigenin, Curcumin, Quercetin, Lycopene, Lupeol. O nei mea aoga e fa'aogaina ai ala fa'aola fa'aola e pei ole WNT Beta Catenin Signaling ma Cell Cycle Checkpoints ma isi. E le fautuaina le Pummelo pe a a'afia i le Erdheim Chester Disease pe a o'o iai fa'afitauli fa'aletagata ole ARAF aua e fa'ateleina ai le saini ala.

FRUIT NANCE E FAATUATUA I LE PUMMELO MO ARAF GENETIC RISK I LE KANESA.

Filifili nati COMMON HAZELNUT po'o EUROPEAN CHESTNUT?

O le Hazelnut masani o loʻo i ai le tele o mea aoga poʻo meaola faʻapitoa e pei o Curcumin, Quercetin, Myricetin, Lycopene, Lupeol. O nei mea aoga e faʻaogaina auala eseese o meaola e pei o Angiogenesis, RAS-RAF Signaling, Cell Cycle ma le PI3K-AKT-MTOR Signaling ma isi. O le Hazelnut masani e fautuaina mo le lamatiaga o le Erdheim Chester Disease pe a o'o i le fa'alavelave fa'aletagata ole ARAF. E mafua ona o le Common Hazelnut e fa'atuputeleina ai auala fa'aola fa'aola e fa'afete'ena'i ai le saini fa'ata'avale.

O nisi o mea aoga poʻo meaola faʻaola i Europa Chestnut o Apigenin, Ellagic Acid, Curcumin, Quercetin, Myricetin. O nei mea aoga e fa'aogaina ai ala fa'aola fa'aola e pei o le WNT Beta Catenin Signaling, PI3K-AKT-MTOR Signaling ma le MYC Signaling ma isi. E le fautuaina le European Chestnut pe a a'afia i le Erdheim Chester Disease pe a o'o iai fa'alavelave fa'aletagata ole ARAF aua e fa'ateleina ai le saini ala.

O LE HAZELNUT MASANI E FAATUATUA IA IA EUROPEAN CHESTNUT MO ARAF GENETIC ATUAGA O LE KANESA.

I le Faaiuga

Mea'ai ma Supplements ua filifilia o ni filifiliga taua mo kanesa pei ole Erdheim Chester Disease. O tagata mama'i o le Erdheim Chester Disease ma tagata ta'ito'atasi e iai a'afiaga tau kenera e masani lava ona i ai le fesili lenei: "O a mea'ai ma mea'ai fa'aopoopo e fautuaina mo a'u ae e leai?" E iai le talitonuga masani ose manatu sese e faapea o mea'ai uma e fa'avae i la'au e mafai ona aoga pe leai ae e le afaina. O nisi mea'ai ma mea'ai fa'aopoopo e mafai ona fa'alavelave i togafitiga o le kanesa po'o le fa'atupuina o le molecular pathway aveta'avale o le kanesa.

E iai ituaiga fa'ailoga o le kanesa e pei o le Erdheim Chester Disease, e tofu lava ma fa'ama'i tumo eseese ma isi suiga fa'agenomic i tagata ta'ito'atasi. E le gata i lea, o togafitiga uma o le kanesa ma le chemotherapy e iai se faiga tulaga ese o gaioiga. O mea'ai ta'itasi e pei o le Eggplant o lo'o iai ni meaola fa'aola i le aofa'i 'ese'ese, e iai sona a'afiaga i seti eseese ma ma'oti o ala fa'aola. O le fa'amatalaga o mea'ai fa'apitoa o mea'ai fa'apitoa mo le fa'ailoga o le kanesa, togafitiga, kenera, olaga ma isi mea. Fa'ai'uga fa'apitoa mo le kanesa e mana'omia le malamalama i le biology o le kanesa, fa'asaienisi mea'ai ma le malamalama i togafitiga eseese o le chemotherapy. Mulimuli ane pe a iai ni suiga o togafitiga po'o fa'ailoa fo'i genomics fou - e mana'omia le toe fa'avasegaina o mea'ai.

O le addon nutrition personalization solution e faigofie ai le faia o filifiliga ma aveese uma taumatematega i le taliina o le fesili, "O a mea'ai e tatau ona ou filifilia pe leai foi mo le Erdheim Chester Disease?". O le addon multi-disciplinary team e aofia ai fomaʻi o le kanesa, saienitisi falemaʻi, inisinia polokalama ma saienitisi faʻamaumauga.

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• https://medlineplus.gov/genetics/condition/erdheim-chester-disease/#resources
• https://rarediseases.org/rare-diseases/erdheim-chester-disease
• https://histio.org/histiocytic-disorders/erdheim-chester-disease
• https://www.lls.org/sites/default/files/2022-07/FS37_Erdheim_Chester_2022.pdf