Mea'ai mo Chordoma!

faʻatomuaga

Mea'ai mo Chordoma e tatau ona fa'apitoa mo tagata ta'ito'atasi ma e tatau fo'i ona fetuuna'i pe a o'o i togafitiga o le kanesa po'o suiga o le tumo. O le fa'avasegaina ma le fetuutuuna'iga e tatau ona mafaufau i mea aoga uma po'o meaola fa'aola o lo'o i totonu o mea'ai eseese e fa'atatau i le biology o le kanesa, genetics, togafitiga, tulaga o le olaga ma mea e fiafia i ai. O le mea lea e ui o mea'ai o se tasi lea o filifiliga taua tele mo se tagata ma'i kanesa ma tagata ta'ito'atasi o lo'o a'afia i le kanesa e fai - o le auala e filifili ai mea'ai e 'ai e le o se galuega faigofie.

Chordoma ose ituaiga kanesa e seasea tupu a'e i ponaivi, e masani ona tupu ile sacrum po'o le ivi si'usi'u (coccyx). O otootoga o le pathology e taua tele i le malamalama i uiga o le chordoma ma le taʻitaʻia o suʻesuʻega saʻo. O metotia fa'a-radiology, e aofia ai su'esu'ega MRI, e taua tele mo le va'aiga ma le su'esu'eina o tumo o le chordoma. O fa'alapotopotoga e pei o le Chordoma Foundation e tu'uina atu le lagolago taua ma punaoa mo gasegase ma fa'alauiloa su'esu'ega i lenei kanesa e seasea maua. Fa'ailoga o le chordoma e mafai ona fesuisuiai ae e mafai ona aofia ai le tiga, malo, ma fa'ailoga neurological i le vaega ua a'afia e pei ole ivi si'usi'u. Ole fua ole ola mo le chordoma e fa'alagolago i mea eseese, e aofia ai le tulaga ma le lautele ole tuma. Fa'ailoga sa'o i le fa'aogaina o le ICD-10 fa'avasegaina faiga fa'amautinoaina lelei fa'amaumauga o chordoma i fa'amaumauga fa'afoma'i. E ui o le chordoma e masani ona fesoʻotaʻi ma tagata, e mafai foi ona tupu i manu e pei o ferrets. O le malamalama i le fa'amatalaga ma uiga o le chordoma e fesoasoani i le iloaina ma le puleaina o lenei kanesa faigata. Chordoma e mafai foi ona aafia ai isi vaega o le tino, e pei o le clivus. Togafitiga mo le chordoma e aofia ai le tele o aʻoaʻoga, e aofia ai le taotoga, togafitiga faʻamalositino, ma le chemotherapy. Togafitiga taʻiala ma faʻataʻitaʻiga faʻapitoa e fesoasoani i le alualu i luma i le pulega o le chordoma. E mafai ona fa'aogaina le kemoterapi i tulaga e le mafai ona toe fa'amama le tumo po'o ua fa'amastasi. O suʻesuʻega vave ma saʻo e taua tele mo le faʻatinoina o togafitiga talafeagai mo chordoma. I le aotelega, o su'esu'ega faifaipea ma togafitiga fou o lo'o tuliloaina ma le malosi e fa'aleleia ai taunu'uga ma tulaga lelei o le olaga mo tagata ta'ito'atasi e a'afia ile chordoma.

Mo Chordoma e afaina po o a fualaau faisua, fualaau aina, nati, fatu e 'ai e se tasi?

O se fesili masani o mea'ai e fesiligia e tagata ma'i kanesa ma tagata ta'ito'atasi e ono maua i le kanesa - mo kanesa e pei o Chordoma e afaina po'o a mea'ai ou te 'ai ae leai? Pe afai ou te mulimuli i se meaʻai e faʻavae i laʻau e lava lena mo le kanesa pei o Chordoma?

Mo se faʻataʻitaʻiga e afaina pe a sili atu le taumafaina o fualaau faisua Globe Artichoke pe a faʻatusatusa i Cardoon? E i ai se eseesega pe a sili atu le fua Pummelo nai lo Rabbiteye Blueberry? Fa'apena fo'i pe a fai filifiliga fa'apena mo nati/ fatu e pei o le Butternut i luga o Pasila Nut ma mo fatu fa'apei o Alfalfa i luga o Lentils. Ma afai e afaina mea ou te 'ai - e faapefea ona iloa e se tasi meaʻai e fautuaina mo Chordoma ma pe tutusa le tali mo tagata uma e tutusa le suʻesuʻega poʻo le faʻafitauli tau kenera?

Ioe! Mea'ai e te 'ai e taua mo Chordoma!

O fautuaga o mea'ai atonu e le tutusa mo tagata uma ma e mafai ona eseese e tusa lava pe tutusa le su'esu'ega ma fa'alavelave fa'aletagata.

Mea'ai uma (fualaau faisua, fualaau 'aina, nati, fatu, fatu, suau'u ma isi mea'ai) ma mea'ai fa'aopoopo o lo'o faia i le sili atu ma le tasi le mole mole ga'o po'o bio-actives i vaega eseese ma aofa'i. O mea aoga ta'itasi o lo'o i ai se faiga fa'apitoa e fa'atino ai - e mafai ona fa'agaoioia pe fa'alavelaveina ala fa'aolaola eseese. O mea'ai ma mea'ai fa'aopoopo o lo'o fautuaina e le fa'atupuina le fa'atuputeleina o mea'ai mole mole o le kanesa ae fa'aitiitia. A leai o na meaai e le tatau ona fautuaina. O mea'ai e aofia ai le tele o mea aoga - o le mea lea pe a iloiloina mea'ai ma mea'ai faaopoopo e tatau ona e mafaufau i le a'afiaga o mea aoga uma fa'aopoopo nai lo le ta'ito'atasi.

Mo se faʻataʻitaʻiga Pummelo o loʻo i ai mea aoga Quercetin, Curcumin, Apigenin, Daidzein, Lupeol. Ma Rabbiteye Blueberry o loʻo i ai mea aoga Quercetin, Linalool, P-coumaric Acid, Geraniol, Eugenol ma atonu o isi.

O se mea sese masani e fai pe a filifili ma filifili mea'ai e 'ai mo Chordoma - o le iloiloina na'o mea aoga filifilia o lo'o i totonu o mea'ai ae le amana'ia isi mea'ai. Ona o mea aoga eseese o lo'o i totonu o mea'ai e ono iai ni a'afiaga fa'afeagai i aveta'avale o le kanesa - e le mafai ona e fa'amalieina le filifilia o mea aoga i mea'ai ma mea fa'aopoopo mo le faia o se filifiliga tau mea'ai mo Chordoma.

IOE – FILIFILIGA O MEAAI E TAUA MO LE KANESA. E TATAU ONA MAFAUFAU I FILIFILIGA FA'ANUI UMA O MEA UA FAI O MEAAI.

Tomai e Manaomia mo Mea'ai Fa'apitoa mo Chordoma?

Mea'ai fa'apitoa mo kanesa e pei o Chordoma e aofia ai mea'ai / fa'aopoopoga fautuaina; mea'ai e le fautuaina / fa'aopoopoga fa'atasi ai ma fa'ata'ita'iga fua e fa'amuamua le fa'aogaina o mea'ai fautuaina. O se faʻataʻitaʻiga o meaʻai faʻapitoa e mafai ona vaʻaia i lenei mea fesoʻotaʻiga.

Ole filifiliga po'o fea mea'ai e fautuaina pe leai e matua faigata lava, e mana'omia ai le poto i le Chordoma biology, food science, genetics, biochemistry fa'atasi ai ma le malamalama lelei i le auala e galue ai togafitiga o le kanesa ma fa'afitauli fa'aletonu e ono taofia ai le aoga.

FA'ATA'ITA'I FA'AMANATU FA'AMATALAGA E MANA'OINA MO FA'A'I'I FA'A'AI MO LE KANESA E IA: KANESA BIOLOGY, SCIENCE FOOD, TAGA'IGA KANESA MA GENETICS.

Uiga o kanesa pei o Chordoma

O kanesa uma e pei o Chordoma e mafai ona faʻaalia i se seti tulaga ese o auala biochemical - o auala saini a Chordoma. O auala faʻaola e pei o le Cell Cycle, Focal Adhesion, PI3K-AKT-MTOR Signaling, Oncogenic Cancer Epigenetics o se vaega o le faʻamatalaga saini o Chordoma. E mafai ona 'ese'ese le kenera o le kanesa o tagata ta'ito'atasi ma o lea e mafai ai ona tulaga ese a latou saini fa'apitoa ole kanesa.

O togafitiga e aoga mo Chordoma e mana'omia le iloa lelei o auala fa'aola biochemical e feso'ota'i mo ma'i kanesa ta'ito'atasi ma tagata ta'ito'atasi o lo'o a'afia i gasegase. O lea la o togafitiga eseese ma auala eseese o gaioiga e aoga mo gasegase eseese. E fa'apena fo'i ma mo mafua'aga lava e tasi e mana'omia ai le fa'apitoa o mea'ai ma mea'ai mo tagata ta'ito'atasi. O le mea lea e fautuaina ai nisi o mea'ai ma mea'ai mo Chordoma pe a fai togafitiga o le kanesa Radiation, ma o nisi mea'ai ma mea'ai faaopoopo e le fautuaina.

Punavai pei cBioPortal ma le tele o isi o lo'o tu'uina mai ai fa'amatalaga o tagata ma'i e le o ta'ua mai fa'ata'ita'iga mo fa'ailoga uma o le kanesa. O nei fa'amaumauga e aofia ai fa'amatalaga su'esu'ega fa'ata'ita'i fa'ata'ita'i e pei o le lapo'a / numera o tagata mama'i, vaitausaga, itupa, ituaiga, togafitiga, nofoaga tumo ma so'o se suiga fa'aletagata.

DNMT3A, GRM5, PIK3CA, TERT ma CDKN2A o le pito i luga o loʻo lipotia genes mo Chordoma. DNMT3A o loʻo lipotia i le 12.0% o sui faʻamaʻi i faʻataʻitaʻiga uma. Ma o le GRM5 o loʻo lipotia i le 8.0%. O fa'amaumauga tu'ufa'atasi o tagata ma'i e aofia ai tausaga mai le 10 i le 85. 58.0 % o fa'amaumauga o ma'i ua fa'ailoaina o tane. O le Chordoma biology fa'atasi ai ma genetics ua lipotia fa'atasi e fa'amatala ai le faitau aofa'i o ala fa'aola biochemical saini mo lenei kanesa. Afai o le tagata ta'ito'atasi o le kanesa tumo genetics po'o genes o lo'o saofagā i le lamatiaga o lo'o iloa fo'i ona tatau lea ona fa'aoga mo le fa'avasegaina o mea'ai.

O FILIFILIGA FA'A'I MEA'AI E TATAU ONA FA'A'OGA MA LE SAINI KANAGA A TA'ATatasi.

Mea'ai ma Mea'ai mo Chordoma

Mo Ma'i Kanesa

E mana'omia e tagata mama'i o le kanesa i togafitiga po'o le tausiga fa'alesoifua maloloina ona fai fa'ai'uga i mea'ai ma mea fa'aopoopo - mo mea'ai e mana'omia, mo le puleaina o so'o se a'afiaga o togafitiga ma fa'apea fo'i le fa'aleleia atili o le puleaina o le kanesa. O mea'ai uma e fa'atatau i la'au e le tutusa ma e taua ma lavelave le filifilia ma le fa'amuamua o mea'ai e fa'apitoa ma fa'apitoa mo togafitiga fa'aauau. O nisi nei o fa'ata'ita'iga o lo'o tu'uina atu ai ta'iala mo le faia o filifiliga o mea'ai.

Filifili Fua'ai GLOBE ARTICHOKE po'o CARDOON?

Vegetable Globe Artichoke o loʻo i ai le tele o mea aoga poʻo meaola faʻapitoa e pei o Curcumin, Apigenin, Daidzein, Lupeol, Luteolin. O nei mea aoga e faʻaogaina auala eseese o meaola e pei o le Extracellular Matrix Remodelling, Cell Cycle, PI3K-AKT-MTOR Signaling ma le MYC Signaling ma isi. O le Globe Artichoke e fautuaina mo Chordoma pe a faʻaauau togafitiga o le kanesa o le Radiation. E mafua ona o le Globe Artichoke e suia na ala o meaola fa'asaienisi ua lipotia fa'asaienisi e fa'amanino ai le a'afiaga o Radiation.

O nisi o mea aoga poʻo bioactives i fualaau faisua Cardoon o Curcumin, Apigenin, Daidzein, Lupeol, Caffeine. O mea aoga ia e fa'aogaina auala fa'aola fa'aola e pei o le DNA Repair ma le Heat Stress Response ma isi. E le fautuaina le Cardoon mo Chordoma pe a fai le togafitiga o le kanesa o le Radiation aua e suia ai na auala biochemical e mafai ai ona tetee le kanesa pe itiiti le tali atu.

ARTICHOKE GLOBE VUGA E FAATUATUA I CARDOON MO Chordoma MA TOGOTAGA Fa'avevela.

Filifili Fualaau RABBITEYE BLUEBERRY poʻo PUMMELO?

Fua Rabbiteye Blueberry o loʻo i ai le tele o mea aoga poʻo meaola faʻapitoa e pei ole Quercetin, Linalool, P-coumaric Acid, Geraniol, Eugenol. O nei mea aoga e faʻaogaina auala eseese o meaola e pei o le Cell Cycle, PI3K-AKT-MTOR Signaling, Oncogenic Cancer Epigenetics ma le MYC Signaling ma isi. Rabbiteye Blueberry e fautuaina mo Chordoma pe a faʻaauau togafitiga o le kanesa o le Radiation. E mafua ona o le Rabbiteye Blueberry e suia na ala o meaola fa'asaienisi ua lipotia fa'asaienitisi e fa'ailoa ai le aafiaga o le Radiation.

O nisi o mea aoga poʻo mea olaola i totonu o fualaau aina Pummelo o Quercetin, Curcumin, Apigenin, Daidzein, Lupeol. O mea aoga ia e fa'aogaina auala fa'aola fa'aola e pei ole DNA Repair ma Heat Stress Response ma isi. E le fautuaina le Pummelo mo Chordoma pe a fai le togafitiga o le kanesa o le Radiation aua e suia ai na auala biochemical e mafai ai ona tetee le kanesa pe itiiti le tali atu.

FRUIT RABBITEYE BLUEBERRY E FAUTUAINA IA PUMMELO MO Chordoma MA TOGOTAGA Radiation.

Filifili Nut BUTTERNUT poʻo BRAZIL NUT?

Butternut o loʻo i ai le tele o mea aoga poʻo meaola faʻapitoa e pei o Curcumin, Apigenin, Daidzein, Lupeol, Caffeine. O lo'o fa'agaoioia nei mea e fa'aogaina auala fa'aola fa'aola e pei o le Cell Cycle, PI3K-AKT-MTOR Signaling ma le MYC Signaling ma isi. O le Butternut e fautuaina mo Chordoma pe a faʻaauau togafitiga o le kanesa o le Radiation. E mafua ona ua suia e Butternut ia auala fa'aola fa'asaienisi ua lipotia fa'asaienitisi e fa'ailoa ai le aafiaga ole Radiation.

O nisi o mea aoga poʻo mea olaola i Brazil Nut o le Ellagic Acid, Curcumin, Daidzein, Lupeol, Formononetin. O nei mea aoga e fa'aogaina ai auala eseese o meaola e pei o le PI3K-AKT-MTOR Signaling, Heat Stress Response ma le MYC Signaling ma isi. E le fautuaina le Pasila Nut mo Chordoma pe a fai o togafitiga o le kanesa o le Radiation aua e suia ai na auala biochemical lea e mafai ai ona tetee le kanesa togafitiga pe itiiti le tali atu.

E FAATUATUA LE BUTTERNUT I LE NUT BRAZIL MO Chordoma MA TOGOTAGA Fa'avevela.

Mo Tagata ta'ito'atasi e iai le lamatiaga o le kanesa

O le fesili na fesiligia e tagata taʻitoʻatasi o loʻo i ai le lamatiaga o le Chordoma poʻo le talafaasolopito o aiga o le "O le a le mea e tatau ona ou 'ai ese mai le taimi muamua?" ma le auala e tatau ona latou filifilia ai mea'ai ma mea faaopoopo e pulea ai tulaga lamatia o le ma'i. Talu ai mo le lamatiaga o le kanesa e leai se mea e mafai ona faia i le tulaga o togafitiga - o filifiliga o meaʻai ma mea faaopoopo e taua tele ma o se tasi o mea laiti e mafai ona fai. O mea'ai uma e fa'atatau i la'au e le tutusa ma fa'avae ile kenera ma saini ala - o filifiliga o mea'ai ma mea'ai e tatau ona fa'apitoa.

Filifili fualaau faisua GIANT BUTTERBUR poʻo CABBAGE BLACK?

Vegetable Giant Butterbur o loʻo i ai le tele o mea aoga poʻo meaola faʻapitoa e pei o Apigenin, Curcumin, Lupeol, Daidzein, Beta-sitosterol. O nei mea aoga e faʻaogaina auala eseese o meaola e pei o Angiogenesis, Cell Cycle, PI3K-AKT-MTOR Signaling ma Stem Cell Signaling ma isi. Giant Butterbur e fautuaina mo le lamatiaga o le Chordoma pe a oʻo i le faʻalavelave faʻaleagaina ole CDKN2A. E mafua ona o Giant Butterbur faʻateleina na auala biochemical e faʻafefe ai le saini avetaavale.

O nisi o mea aoga po'o mea olaola i fualaau faisua Kapisi Uliuli o le Apigenin, Curcumin, Lupeol, Daidzein, Beta-sitosterol. O nei mea aoga e faʻaogaina auala eseese o meaola e pei o Stem Cell Signaling ma Oncogenic Cancer Epigenetics ma isi. E le fautuaina le Kapisi Uliuli pe a a'afia le Chordoma pe a o'o iai le fa'alavelave fa'aletagata o le CDKN2A aua e fa'ateleina ai le saini ala.

E FAATUATUA LE PATI LAUAU LAUUA I LE KAPISI ULITIA MO CDKN2A ATUAGA I LE KANESA.

Filifili Fualaau NANCE po'o MALUS (CRAB APPLE)?

Fua Nance o loʻo i ai le tele o mea aoga poʻo meaola faʻapitoa e pei ole Apigenin, Curcumin, Lupeol, Daidzein, Beta-sitosterol. O nei mea aoga e faʻaogaina auala eseese o meaola e pei o Cell Cycle, PI3K-AKT-MTOR Signaling ma Hypoxia ma isi. E fautuaina le Nance mo le lamatiaga o le Chordoma pe a o'o i le fa'alavelave fa'aletagata ole CDKN2A. E mafua ona ua fa'ateleina e Nance ia auala fa'aolaola e fa'afete'ena'i ai le saini o lo'o ave ai.

O nisi o mea aoga po'o mea olaola i totonu o fualaau aina Malus (Apu Apple) o le Apigenin, Curcumin, Lupeol, Daidzein, Beta-sitosterol. O nei mea aoga e fa'aogaina ai auala fa'aola fa'aola e pei o Stem Cell Signaling ma Cell Cycle Checkpoints ma isi. Malus (crab Apple) e le fautuaina pe a lamatia le Chordoma pe a a'afia fa'atupu fa'alavelave ole CDKN2A aua e fa'ateleina ai le saini ala o ia.

FRUIT NANCE E FAATUATUA I MALUS (CRAB APPLE) MO CDKN2A GENETIC RISK OF CANCER.

Filifili nati COMMON WALNUT po'o EUROPEAN CHESTNUT?

O Walnut masani o loʻo i ai le tele o mea aoga poʻo meaola faʻapitoa e pei o Curcumin, Quercetin, Lupeol, Ellagic Acid, Daidzein. O nei mea aoga e faʻaogaina auala eseese o meaola e pei o Angiogenesis, Cell Cycle, PI3K-AKT-MTOR Signaling ma Stem Cell Signaling ma isi. O le Walnut masani e fautuaina mo le lamatiaga o le Chordoma pe a o'o i le fa'alavelave fa'aletagata ole CDKN2A. E mafua ona o le Common Walnut e fa'ateleina ala fa'aola fa'aola e fa'afete'ena'i ai le saini fa'ata'avale.

O nisi o mea aoga poʻo meaola faʻaola i Europa Chestnut o Apigenin, Curcumin, Quercetin, Lupeol, Ellagic Acid. O nei mea aoga e fa'aogaina auala fa'aola fa'aola e pei o Stem Cell Signaling ma isi. E le fautuaina le European Chestnut pe a lamatia le Chordoma pe a o'o i le CDKN2A fa'afitauli ona e fa'ateleina ai le saini ala.

UA FAATUATUA LE COMMON WALNUT IA EUROPEAN CHESTNUT MO CDKN2A GENETIC RISK OF CANCER.

I le Faaiuga

Mea'ai ma Supplements ua filifilia o ni filifiliga taua mo kanesa pei o Chordoma. O tagata maʻi Chordoma ma tagata taʻitoʻatasi e iai aʻafiaga faʻaleagaina e masani lava ona i ai le fesili lenei: "O a meaʻai ma meaʻai faʻaopoopo e fautuaina mo aʻu ae e leai?" E iai le talitonuga masani ose manatu sese e faapea o mea'ai uma e fa'avae i la'au e mafai ona aoga pe leai ae e le afaina. O nisi mea'ai ma mea'ai fa'aopoopo e mafai ona fa'alavelave i togafitiga o le kanesa po'o le fa'atupuina o le molecular pathway aveta'avale o le kanesa.

E 'ese'ese ituaiga fa'ailoga o le kanesa e pei o Chordoma, e ta'itasi ma tu'u fa'atupu fa'ama'i fa'atasi ai ma isi fa'asologa o genomic i tagata ta'ito'atasi. E le gata i lea, o togafitiga uma o le kanesa ma le chemotherapy e iai se faiga tulaga ese o gaioiga. O mea'ai ta'itasi e pei o le Globe Artichoke o lo'o i ai bioactives eseese i aofa'iga 'ese'ese, e iai sona a'afiaga i seti eseese ma ma'oti o auala fa'aola. O le fa'amatalaga o mea'ai fa'apitoa o mea'ai fa'apitoa mo le fa'ailoga o le kanesa, togafitiga, kenera, olaga ma isi mea. Fa'ai'uga fa'apitoa mo le kanesa e mana'omia le malamalama i le biology o le kanesa, fa'asaienisi mea'ai ma le malamalama i togafitiga eseese o le chemotherapy. Mulimuli ane pe a iai ni suiga o togafitiga po'o fa'ailoa fo'i genomics fou - e mana'omia le toe fa'avasegaina o mea'ai.

O le addon nutrition personalization solution e faigofie ai le faia o filifiliga ma aveese uma taumatematega i le taliina o le fesili, "O a meaʻai e tatau ona ou filifilia pe le filifilia mo Chordoma?". O le addon multi-disciplinary team e aofia ai fomaʻi o le kanesa, saienitisi falemaʻi, inisinia polokalama ma saienitisi faʻamaumauga.

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• https://www.ncbi.nlm.nih.gov/books/NBK430846
• https://my.clevelandclinic.org/health/diseases/17916-chordomas