faʻatomuaga
Mea'ai mo le Myelodysplastic Syndrome e feso'ota'i i Togafitiga e tatau ona fa'apitoa mo tagata ta'ito'atasi ma e tatau fo'i ona fetuutuunai pe a suia togafitiga ole kanesa po'o le tumo. O le fa'avasegaina ma le fetuutuuna'iga e tatau ona mafaufau i mea aoga uma po'o meaola fa'aola o lo'o i totonu o mea'ai eseese e fa'atatau i le biology o le kanesa, genetics, togafitiga, tulaga o le olaga ma mea e fiafia i ai. O le mea lea e ui o mea'ai o se tasi lea o filifiliga taua tele mo se tagata ma'i kanesa ma tagata ta'ito'atasi o lo'o a'afia i le kanesa e fai - o le auala e filifili ai mea'ai e 'ai e le o se galuega faigofie.
O se fesili masani o mea'ai e fesiligia e tagata ma'i kanesa ma tagata ta'ito'atasi e ono maua i le kanesa o le - mo kanesa e pei ole Therapy-related Myelodysplastic Syndrome e afaina po'o a mea'ai ou te 'ai ae ou te le faia? Pe afai ou te mulimulita'i i se mea'ai e fa'atatau i la'au ua lava lea mo le kanesa e pei ole Therapy-related Myelodysplastic Syndrome?
Mo se fa'ata'ita'iga e afaina pe a fa'atauina le latisi fuala'au pe a fa'atusatusa i le Arrowhead? E iai se eseesega pe afai e sili atu le fua Pummelo nai lo Mandarin Orange (clementine, Tangerine)? Fa'apena fo'i pe a fai filifiliga fa'apena mo nati/ fatu e pei o le Butternut i luga o le Macadamia Nut ma mo pulus pei ole Broad Bean i luga ole Common Bean. Ae afai e afaina mea ou te 'ai - e faapefea la ona iloa e se tasi mea'ai e fautuaina mo le Therapy-related Myelodysplastic Syndrome ma pe tutusa le tali mo tagata uma e tutusa le suʻesuʻega poʻo le faʻalavelave faʻaleagaina?
Ioe! O mea'ai e te 'ai e taua mo Togafitiga e feso'ota'i ma le Myelodysplastic Syndrome!
O fautuaga o mea'ai atonu e le tutusa mo tagata uma ma e mafai ona eseese e tusa lava pe tutusa le su'esu'ega ma fa'alavelave fa'aletagata.
Mea'ai uma (fualaau faisua, fualaau 'aina, nati, fatu, fatu, suau'u ma isi mea'ai) ma mea'ai fa'aopoopo o lo'o faia i le sili atu ma le tasi le mole mole ga'o po'o bio-actives i vaega eseese ma aofa'i. O mea aoga ta'itasi o lo'o i ai se faiga fa'apitoa e fa'atino ai - e mafai ona fa'agaoioia pe fa'alavelaveina ala fa'aolaola eseese. O mea'ai ma mea'ai fa'aopoopo o lo'o fautuaina e le fa'atupuina le fa'atuputeleina o mea'ai mole mole o le kanesa ae fa'aitiitia. A leai o na meaai e le tatau ona fautuaina. O mea'ai e aofia ai le tele o mea aoga - o le mea lea pe a iloiloina mea'ai ma mea'ai faaopoopo e tatau ona e mafaufau i le a'afiaga o mea aoga uma fa'aopoopo nai lo le ta'ito'atasi.
Mo se faʻataʻitaʻiga Pummelo o loʻo i ai mea aoga Apigenin, Curcumin, Lycopene, Protocatechuic Acid, Lupeol. Ma Mandarin Orange (clementine, Tangerine) o loʻo i ai mea aoga Curcumin, Linalool, Protocatechuic Acid, Lupeol, Daidzein ma atonu o isi.
O se mea sese masani e fai pe a filifili ma filifili mea'ai e 'ai mo le Therapy-related Myelodysplastic Syndrome - o le iloiloina na'o mea aoga ua filifilia o lo'o i totonu o mea'ai ae le amana'ia isi mea. Ona o mea aoga eseese o lo'o i totonu o mea'ai e ono iai ni a'afiaga fa'afeagai i aveta'avale o le kanesa - e le mafai ona e fa'amalieina le filifilia o mea aoga i mea'ai ma mea fa'aopoopo mo le faia o se fa'ai'uga o mea'ai mo le Togafitiga o le Myelodysplastic Syndrome.
IOE – FILIFILIGA O MEAAI E TAUA MO LE KANESA. E TATAU ONA MAFAUFAU I FILIFILIGA FA'ANUI UMA O MEA UA FAI O MEAAI.
Mea'ai fa'apitoa mo kanesa e pei ole Togafitiga ile Myelodysplastic Syndrome e aofia ai mea'ai / fa'aopoopoga fautuaina; mea'ai e le fautuaina / fa'aopoopoga fa'atasi ai ma fa'ata'ita'iga fua e fa'amuamua le fa'aogaina o mea'ai fautuaina. O se faʻataʻitaʻiga o meaʻai faʻapitoa e mafai ona vaʻaia i lenei mea fesoʻotaʻiga.
Ole filifiliga po'o fea mea'ai e fautuaina pe leai e matua faigata lava, e mana'omia ai le tomai ile Therapy-related Myelodysplastic Syndrome biology, food science, genetics, biochemistry fa'atasi ai ma le malamalama lelei ile auala e galue ai togafitiga o le kanesa ma fa'afitauli fa'aletonu e ono taofia ai le aoga.
FA'ATA'ITA'I FA'AMANATU FA'AMATALAGA E MANA'OINA MO FA'A'I'I FA'A'AI MO LE KANESA E IA: KANESA BIOLOGY, SCIENCE FOOD, TAGA'IGA KANESA MA GENETICS.
Meaʻai e 'ai Ina ua maeʻa faʻamaʻi kanesa!
Leai lua kanesa e tutusa. Alu i talaatu o le masani taʻiala taiala mo tagata uma ma faia filifiliga faʻapitoa e uiga i meaʻai ma faʻaopopoga ma le mautinoa.
O kanesa uma e pei ole Therapy-related Myelodysplastic Syndrome e mafai ona fa'ailoaina ile seti tulaga ese ole biochemical pathways - o auala saini ole Therapy-related Myelodysplastic Syndrome. O auala fa'aola e pei o le PI3K-AKT-MTOR Signaling, mRNA Splicing, Oncogenic Cancer Epigenetics, Cell Cycle Checkpoints o se vaega o le saini fa'auigaina ole Therapy-related Myelodysplastic Syndrome. E mafai ona 'ese'ese le kenera o le kanesa o tagata ta'ito'atasi ma o lea e mafai ai ona tulaga ese a latou saini fa'apitoa ole kanesa.
O togafitiga e aoga mo le Myelodysplastic Syndrome e feso'otai i Togafitiga e mana'omia le iloa lelei o ala fa'aola fa'aola mo tagata ma'i kanesa ta'ito'atasi ma tagata ta'ito'atasi o lo'o a'afia i gasegase. O lea la o togafitiga eseese ma auala eseese o gaioiga e aoga mo gasegase eseese. E fa'apena fo'i ma mo mafua'aga lava e tasi e mana'omia ai le fa'apitoa o mea'ai ma mea'ai mo tagata ta'ito'atasi. O lea ua fautuaina ai nisi o mea'ai ma mea'ai mo le Myelodysplastic Syndrome e feso'ota'i i Togafitiga pe a fai togafitiga o le kanesa o le Fludarabine, ma o nisi mea'ai ma mea'ai faaopoopo e le fautuaina.
Punavai pei cBioPortal ma le tele o isi o lo'o tu'uina mai ai fa'amatalaga o tagata ma'i e le o ta'ua mai fa'ata'ita'iga mo fa'ailoga uma o le kanesa. O nei fa'amaumauga e aofia ai fa'amatalaga su'esu'ega fa'ata'ita'i fa'ata'ita'i e pei o le lapo'a / numera o tagata mama'i, vaitausaga, itupa, ituaiga, togafitiga, nofoaga tumo ma so'o se suiga fa'aletagata.
O le TP53, TET2, ASXL1, EZH2 ma le ZRSR2 o lo'o i luga o fa'asologa o kenera ua lipotia mo le Togafitiga e feso'ota'i ma Myelodysplastic Syndrome. O le TP53 o loʻo lipotia i le 63.6% o sui o gasegase i faʻataʻitaʻiga uma. Ma ua lipotia le TET2 i le 27.3%. O fa'amaumauga tu'ufa'atasi o tagata ma'i e aofia ai tausaga mai le . 0.0% o faʻamaumauga o maʻi ua faʻamaonia o tane. Ole Therapy-related Myelodysplastic Syndrome biology fa'atasi ai ma genetics ua lipotia fa'atasi e fa'amatala fa'atasi ai le faitau aofa'i o le faitau aofa'i o ala fa'aola kemikolo mo lenei kanesa. Afai o le tagata ta'ito'atasi o le kanesa tumo genetics po'o genes o lo'o saofagā i le lamatiaga o lo'o iloa fo'i ona tatau lea ona fa'aoga mo le fa'avasegaina o mea'ai.
O FILIFILIGA FA'A'I MEA'AI E TATAU ONA FA'A'OGA MA LE SAINI KANAGA A TA'ATatasi.
Mo Ma'i Kanesa
E mana'omia e tagata mama'i o le kanesa i togafitiga po'o le tausiga fa'alesoifua maloloina ona fai fa'ai'uga i mea'ai ma mea fa'aopoopo - mo mea'ai e mana'omia, mo le puleaina o so'o se a'afiaga o togafitiga ma fa'apea fo'i le fa'aleleia atili o le puleaina o le kanesa. O mea'ai uma e fa'atatau i la'au e le tutusa ma e taua ma lavelave le filifilia ma le fa'amuamua o mea'ai e fa'apitoa ma fa'apitoa mo togafitiga fa'aauau. O nisi nei o fa'ata'ita'iga o lo'o tu'uina atu ai ta'iala mo le faia o filifiliga o mea'ai.
Filifili Latisi Fua'ai po'o le ARROWHEAD?
Latisi fuala'au e iai le tele o mea aoga po'o meaola fa'aola e pei o Curcumin, Protocatechuic Acid, Lupeol, Daidzein, Formononetin. O nei mea aoga e faʻaogaina auala eseese o meaola e pei o Apoptosis, PI3K-AKT-MTOR Signaling ma MYC Signaling ma isi. E fautuaina le latisi mo togafitiga ole Myelodysplastic Syndrome pe a fai ole togafitiga ole kanesa ole Fludarabine. E mafua ona ua suia e le Lettuce ia auala fa'aola fa'asaienisi ua lipotia fa'asaienitisi e fa'ailoa ai le aafiaga ole Fludarabine.
O nisi o mea aoga poʻo meaola faʻaola i fualaau faisua Arrowhead o Apigenin, Curcumin, Lycopene, Protocatechuic Acid, Lupeol. O nei mea aoga e faʻaogaina auala eseese o meaola e pei o Cell Cycle Checkpoints ma mRNA Splicing ma isi. E le fautuaina le Arrowhead mo le Therapy-related Myelodysplastic Syndrome pe a fai o togafitiga o le kanesa o le Fludarabine aua e suia ai na auala biochemical e mafai ai ona tetee le kanesa togafitiga pe itiiti le tali atu.
E FAATUATUA LE LUSUSI FA'A'AU FA'A'AU MO FOLAFAGA E feso'ota'i ma le Myelodysplastic Syndrome MA TOGAGA Fludarabine.
Filifili Fualaau MANDARIN ORANGE (CLEMENTINE, TANGERINE) poʻo PUMMELO?
Fua Mandarin Orange (clementine, Tangerine) o loʻo i ai le tele o mea aoga poʻo meaola faʻapitoa e pei o Curcumin, Linalool, Protocatechuic Acid, Lupeol, Daidzein. O nei mea aoga e faʻaogaina auala eseese o meaola e pei o Apoptosis, P53 Signaling, MAPK Signaling ma Cell Cycle Checkpoints ma isi. Mandarin Orange (clementine, Tangerine) e fautuaina mo Togafitiga e fesoʻotaʻi ma Myelodysplastic Syndrome pe a faʻaauau togafitiga o le kanesa o le Fludarabine. E mafua ona o le Mandarin Orange (clementine, Tangerine) e suia na auala faʻaolaola ua lipotia faʻasaienisi e faʻaalia ai le aafiaga o le Fludarabine.
O nisi o mea aoga poʻo meaola olaola i totonu o fualaau aina Pummelo o Apigenin, Curcumin, Lycopene, Protocatechuic Acid, Lupeol. O nei mea aoga e faʻaogaina auala eseese o meaola e pei o Cell Cycle Checkpoints, PI3K-AKT-MTOR Signaling ma mRNA Splicing ma isi. E le fautuaina le Pummelo mo le Myelodysplastic Syndrome e feso'ota'i i Togafitiga pe a fa'aauau le togafitiga o le kanesa o le Fludarabine aua e suia ai na ala fa'aola kemikolo e fa'asa'o ai le togafitiga o le kanesa pe itiiti le tali atu.
FRUIT MANDARIN ORANGE (CLEMENTINE, TANGERINE) E FAATUATUA IA PUMMELO MO Togafitiga e fesoʻotaʻi ma Myelodysplastic Syndrome MA TOGAGA Fludarabine.
Filifili Nut BUTTERNUT poʻo MACADAMIA NUT?
Butternut o loʻo i ai le tele o mea aoga poʻo meaola faʻapitoa e pei ole Apigenin, Curcumin, Lycopene, Protocatechuic Acid, Lupeol. O nei mea aoga e fa'aogaina ai auala fa'aola fa'aola e pei o Apoptosis, P53 Signaling, MAPK Signaling ma MYC Signaling ma isi. O le Butternut e fautuaina mo le Togafitiga e feso'ota'i ma le Myelodysplastic Syndrome pe a fa'aauau le togafitiga ole kanesa ole Fludarabine. E mafua ona ua suia e Butternut ia auala faʻaola faʻasaienisi ua lipotia faʻasaienisi e faʻaalia ai le aafiaga ole Fludarabine.
O nisi o mea aoga poʻo meaola faʻapitoa i Macadamia Nut o Apigenin, Curcumin, Protocatechuic Acid, Lupeol, Daidzein. O lo'o fa'agaoioia nei mea e fa'aogaina ai auala fa'aolaola e pei o le MAPK Signaling ma le PI3K-AKT-MTOR Signaling ma isi. E le fautuaina le Nut Macadamia mo le Myelodysplastic Syndrome e feso'ota'i i Togafitiga pe a fa'aauau le togafitiga o le kanesa o le Fludarabine aua e fa'aleleia ai auala fa'aola fa'aola e fa'asa'o ai le togafitiga o le kanesa pe itiiti le tali atu.
E FAATUATUA LE PUTTERNUT I LE MACADAMIA NUT MO FOLAFAGA E feso'ota'i ma le Myelodysplastic Syndrome MA TOFOAGA Fludarabine.
Mo Tagata ta'ito'atasi e iai le lamatiaga o le kanesa
O le fesili e fesiligia e tagata taʻitoʻatasi o loʻo iai aʻafiaga faʻaleagaga o le Myelodysplastic Syndrome e fesoʻotaʻi ma le Togafitiga poʻo talafaasolopito o aiga o le "O le a le mea e tatau ona ou 'ai ese mai le taimi muamua?" ma le auala e tatau ona latou filifilia ai meaai ma mea faaopoopo e pulea ai tulaga lamatia o le faamai. Talu ai mo le lamatiaga o le kanesa e leai se mea e mafai ona faia i le tulaga o togafitiga - o filifiliga o meaʻai ma mea faaopoopo e taua ma o se tasi o nai mea e mafai ona fai e mafai ona fai. O mea'ai uma e fa'atatau i la'au e le tutusa ma fa'avae i luga ole kenera ma saini ala - o filifiliga o mea'ai ma mea'ai e tatau ona fa'apitoa.
Filifili Fua'ai CALABASH po'o YAM?
Vegetable Calabash o loʻo i ai le tele o mea aoga poʻo meaola faʻapitoa e pei ole Apigenin, Curcumin, Formononetin, Lupeol, Daidzein. O lo'o fa'agaoioia nei mea e fa'aogaina ai ala fa'aolaola e pei o le JAK-STAT Signaling, P53 Signaling, MAPK Signaling ma Cell Cycle Checkpoints ma isi. E fautuaina le Calabash mo le lamatiaga o le Myelodysplastic Syndrome e feso'ota'i i Togafitiga pe a o'o iai le a'afiaga fa'aletagata ole ASXL1. E mafua ona o le Calabash e faʻateleina auala faʻaola e faʻafefe ai le saini o loʻo ave ai.
O nisi o mea aoga po'o meaola fa'aola i totonu o fualaau faisua o le Apigenin, Curcumin, Formononetin, Lupeol, Daidzein. O nei mea aoga e faʻaogaina auala eseese o meaola e pei ole Oxidative Stress ma Oncogenic Cancer Epigenetics ma isi. E le fautuaina le ufi pe a a'afia i le Myelodysplastic Syndrome e feso'ota'i ile Togafitiga pe a o'o ile ASXL1 ona fa'ateleina ai le saini ala.
E FAATUATUA LE KALABASH IA UGA MO LE ASXL1 ATUAGA I LE KANESA.
Filifili Fua'A'AU WATERMELON po'o ALASKA BLUEBERRY?
Fua Suavai o loʻo i ai le tele o mea aoga poʻo meaola faʻapitoa e pei o Curcumin, Formononetin, Lupeol, Daidzein, Bergapten. O lo'o fa'agaoioia nei mea e fa'aogaina ai ala fa'aolaola e pei o le JAK-STAT Signaling, P53 Signaling, MAPK Signaling ma Cell Cycle Checkpoints ma isi. E fautuaina le meleni mo le lamatiaga o le Myelodysplastic Syndrome e feso'ota'i i Togafitiga pe a o'o iai fa'ama'i fa'aletagata ole ASXL1. E mafua ona o le Meleni e fa'ateleina ai auala fa'aolaola e fa'afete'ena'i ai le saini a le aveta'avale.
O nisi o mea aoga po'o meaola fa'aola i fua Alaska Blueberry o le Apigenin, Curcumin, Formononetin, Lupeol, Daidzein. O nei mea aoga e faʻaogaina auala eseese o meaola e pei ole Oxidative Stress ma Oncogenic Cancer Epigenetics ma isi. E le fautuaina le Alaska Blueberry pe a a'afia ile Therapy-related Myelodysplastic Syndrome pe a fa'agata fa'ama'i fa'atupu ole ASXL1 aua e fa'ateleina ai le saini ala.
E FAATUATUA IA LE ALASKA BLUEBERRY MO LE ASXL1 GENETIC RISK I LE KANESA.
Filifili nati COMMON HAZELNUT poʻo CHESTNUT?
Common Hazelnut o loʻo i ai le tele o mea aoga poʻo meaola faʻapitoa e pei o Curcumin, Quercetin, Formononetin, Lupeol, Daidzein. O lo'o fa'agaoioia nei mea e fa'aogaina ai ala fa'aolaola e pei o le JAK-STAT Signaling, P53 Signaling, MAPK Signaling ma Cell Cycle Checkpoints ma isi. O le Hazelnut masani e fautuaina mo le lamatiaga o le Myelodysplastic Syndrome e fesoʻotaʻi i Togafitiga pe a oʻo i le faʻamaʻi pipisi ole ASXL1. E mafua ona o le Common Hazelnut e fa'atuputeleina ai auala fa'aola fa'aola e fa'afete'ena'i ai le saini fa'ata'avale.
O nisi o mea aoga poʻo mea olaola i Chestnut o Apigenin, Curcumin, Ellagic Acid, Formononetin, Lupeol. O nei mea aoga e faʻaogaina auala eseese o meaola e pei ole Oxidative Stress ma Oncogenic Cancer Epigenetics ma isi. E le fautuaina le Chestnut pe a a'afia i le Myelodysplastic Syndrome e feso'ota'i i Togafiti pe a o'o iai le fa'alavelave fa'aletagata ole ASXL1 aua e fa'ateleina ai le saini ala.
O LE HAZELNUT MASANI E FAUTUA I LE CHESTNUT MO LE ASXL1 ATUAGA I LE KANESA.
I le Faaiuga
Mea'ai ma Mea'ai ua filifilia o ni fa'ai'uga taua mo kanesa e pei ole Togafitiga ole Myelodysplastic Syndrome. Ole Myelodysplastic Syndrome e feso'ota'i ile Togafitiga ma tagata ta'ito'atasi e iai a'afiaga tau kenera e masani lava ona i ai le fesili lenei: "O a mea'ai ma mea'ai fa'aopoopo e fautuaina mo a'u ae e leai?" E iai le talitonuga masani ose manatu sese e faapea o mea'ai uma e fa'avae i la'au e mafai ona aoga pe leai ae e le afaina. O nisi mea'ai ma mea'ai fa'aopoopo e mafai ona fa'alavelave i togafitiga o le kanesa po'o le fa'atupuina o le molecular pathway aveta'avale o le kanesa.
E eseese ituaiga o fa'ailoga ole kanesa e pei ole Therapy-related Myelodysplastic Syndrome, e tofu lava ma fa'ama'i tumo 'ese'ese fa'atasi ai ma isi suiga fa'agenomic i tagata ta'ito'atasi. E le gata i lea, o togafitiga uma o le kanesa ma le chemotherapy ei ai se faiga tulaga ese o gaioiga. O mea'ai ta'itasi e pei o le Lettuce o lo'o i ai bioactives eseese i aofa'iga 'ese'ese, e iai sona a'afiaga i seti eseese ma ma'oti o ala fa'aola. O le fa'amatalaga o mea'ai fa'apitoa o mea'ai fa'apitoa mo le fa'ailoga o le kanesa, togafitiga, kenera, olaga ma isi mea. Fa'ai'uga fa'apitoa mo le kanesa e mana'omia le malamalama i le biology o le kanesa, fa'asaienisi mea'ai ma le malamalama i togafitiga eseese o le chemotherapy. Mulimuli ane pe a iai ni suiga o togafitiga po'o fa'ailoa fo'i genomics fou - e mana'omia le toe fa'avasegaina o mea'ai.
O le addon nutrition personalization solution e faigofie ai le faia o filifiliga ma aveese uma taumatematega i le taliina o le fesili, "O a mea'ai e tatau ona ou filifilia pe le filifilia mo le Therapy-related Myelodysplastic Syndrome?". O le addon multi-disciplinary team e aofia ai fomaʻi o le kanesa, saienitisi falemaʻi, inisinia polokalama ma saienitisi faʻamaumauga.
Mea'ai Fa'apitoa mo Kanesa!
E suia le kanesa i le taimi. Fa'asinomaga ma fesuia'i au mea'ai e fa'atatau i fa'ailoga o le kanesa, togafitiga, ituaiga olaga, mea'ai e fiafia i ai, allergies ma isi mea.
mau faasino
- Mds Mskcc 2020
- Hesperidin fa'aoso apoptosis ma G0/G1 pu'eina i le tagata e le o ni tama'i sela mama kanesa A549 sela.
- Su'esu'ega alualu i luma ile a'afiaga ole kanesa ole vaitamini K2.
- Fa'aosofia le tuputupu a'e o sela adenocarcinoma pulmonary tagata ma sela laiti epithelial ea e ala i le beta-carotene e ala i le fa'agaoioia o le cAMP, PKA, CREB ma ERK1/2.
- Formonetin e taofiofia le faʻateleina o le kanesa o le mama sela e le o ni tamaʻi sela e ala i le faʻaosoina o le puʻeina o le taamilosaga ma le apoptosis.