faatumutumuga
E leai ni kanesa se lua e tutusa, e le tutusa foi togafitiga, ma e le tatau foi ona tutusa meaʻai mo tagata uma. Mea'ai e aofia ai mea'ai e pei o fatu, fualaau faisua, fualaau 'aina, nati, suauu, laau afu ma mea manogi. E iai fo'i mea'ai e aofia ai fa'aopoopoga o mea'ai maualuga po'o le maualuga o mea'ai e maua i mea'ai. Mo kanesa e pei o le Multiple Myeloma pe a e faia le chemotherapy po'o le taimi e te iloa ai o lo'o i ai sau fa'alavelave fa'aletagata mo le atia'e o le Multiple Myeloma ona o suiga ole gene NRAS ma BRAF, o se fesili taua tele "O a mea'ai e tatau ona ou aloese mai ai ma o a mea'ai e fautuaina faapitoa mo au?" . O le isi fesili fa'atatau o le "O a ni mea'ai fa'aopoopo e tatau ona ou 'alofia?".
E leai se tasi tali i lenei fesili mo gasegase pei ole Multiple Myeloma lea e mafai ona maua ile su'esu'ega ile initaneti. O le tali i le fesili "E Fa'alagolago" aua o le fuafuaga o mea'ai e tatau ona fa'apitoa mo oe. O mea'ai e tatau ona fa'alagolago i le fa'ailoga o le kanesa, fa'amatalaga tau kenera, matua po'o tamaiti, fa'asologa, tulaga muamua po'o le lua, maualuga, metastatic, toe fa'afo'i po'o fa'aletonu, togafitiga faifaipea pe a iai, mea'ai fa'aopoopo e ave, tausaga ma mea e pei o le itupa, mamafa, maualuga, olaga. , allergies ma mea'ai e fiafia i ai.
I se faapuupuuga - o le faagasologa e tali ai fesili e pei o le "Pe tatau ona ou aloese mai le aiina o fualaau aina Passion Fruit" poʻo le "Faʻaaofia fualaau aina Partridgeberry i laʻu meaʻai" poʻo le "Pe tatau ona ou faʻaitiitia le taumafaina o fualaau faisua Uila" poʻo le "E mafai ona ou inu Ellagic Acid ma Dim supplements" e le faigofie pei o sailiga i luga ole laiga. O le faagasologa e matua faigata ma o tali e faʻavae i luga o le iloa o genetics, gaioiga o togafitiga, mea aoga i meaʻai ma a latou gaioiga faʻaola. Mulimuli ane, o le tali i le fesili tau taumafa e tatau ona fa'apitoa mo oe.
FAUTUAGA: FA'ATA'ATA'I IA AU MEA'AI MA FA'AIGA FA'AVAE I LE MELELOMA FA'AVAE, TO'IGA, FA'AMATALAGA FA'AGA, MA ISI TU'IGA.
O le fa'amoemoe atoa o mea'ai fa'apitoa mo le Multiple Myeloma o le fa'aitiitia lea o mea'ai ma mea'ai fa'aopoopo o lo'o iai a'afiaga leaga ma aveta'avale mole mole kanesa ma togafitiga faifaipea. Ma fa'ailoa na mea'ai ma fa'aopoopoga o lo'o i ai se gaioiga aoga. So'o se taimi e iai suiga i togafitiga po'o su'esu'ega - e taua le manatua o au mea'ai ma mea'ai e mana'omia le toe iloiloga. Ma o tali i le fesili o mea'ai e mafai ona eseese e fa'atatau i le tala fou.
FAUTUAGA: FA'ATAU AU MEAAI MO LE MYELOMA MELE, PE A SUIA TOGIGA, TULAGA FA'I MA ISI TU'IGA.
E uiga i le Myeloma Tele
cBioPortal ose tasi puna o le aoina o kanesa fa'amaumauga o gasegase mai su'esu'ega fa'apitoa ile 350 fa'atasi ma fa'ailoga ole kanesa. O faʻamaumauga mai faʻataʻitaʻiga taʻitasi e aofia ai le igoa ole suʻesuʻega ile falemaʻi ma faʻamatalaga suʻesuʻe e pei ole numera o tagata mamaʻi, tausaga, itupa, ituaiga, togafitiga, nofoaga o le tumo, faʻasologa o kenera na maua ma auʻiliʻiliga o faʻamaumauga uma. O le cBioPortal mo Cancer Genomics na muamua fausia i le Memorial Sloan Kettering Cancer Center (MSK). O le nofoaga lautele cBioPortal o loʻo talimalo ai le Nofoaga Autu mo Molecular Oncology i MSK - https://www.cbioportal.org/about.
O le mulimuli i fa'ailoga autu e maua mai fa'amatalaga fa'apitoa mo le tele o Myeloma mai le cBioPortal. O tagata gasegase na lesitalaina i suʻesuʻega mo le Multiple Myeloma o loʻo i le va o le 24 i le 82 ma le averesi o tausaga o le 61. 66.2% o tane ma le 33.8% o fafine o le tufatufaina o itupa i nei suʻesuʻega faʻapitoa. Mai se fa'ata'ita'iga fa'ata'ita'i ma'i o le 212; o kenera pito i luga e iai suiga ma isi fa'alavelave mo Multiple Myeloma e aofia ai kenera KRAS, NRAS, TP53, BRAF ma MUC16. Ole fa'asologa ole fa'asologa o fa'asologa mo nei kenera e 22.0%, 18.0%, 7.3%, 6.3% ma le 6.3%. O nei fa'amatalaga fa'atupu tumo ole Multiple Myeloma o lo'o fa'afanua ile molecular biochemical pathway aveta'avale ole kanesa ma maua ai le fa'amatalaga o uiga uiga ole Multiple Myeloma.
O le tele o le myeloma o se kanesa o le toto o sela plasma o loʻo maua i le gaʻo ponaivi, o le aano omomi i totonu o tatou ponaivi, lea e masani ona fatuina vaega eseese o tatou toto. O sela plasma o se vaega taua o le puipuiga o le tino. Latou te gaosia antibodies e fesoasoani i le tino e tetee atu i siama. E amata le Myeloma pe a suia sela ola maloloina ma tupu le pulea. E ono i'u ai i le tele o manu'a ponaivi e fa'ateleina ai le ono gau o ponaivi, lea e ta'ua o le myeloma tele. O sela plasma e le masani ai e vaevae vave e mafai ona lolofi i fafo pe taofia le tuputupu aʻe o isi sela i le gaʻo ponaivi, e aofia ai sela mumu, sela paʻepaʻe ma platelets. E le gata ina fa'aitiitia ai le puipuiga o le tino, ae mafai fo'i ona fa'atupu ai le anemia ona o le le lava o sela mūmū, o le tele o le toto fa'atasi ma nai tipi laiti ma manu'a ona o le le lava o platelets, ma fa'aitiitia ai le malosi e tete'e ai fa'ama'i pipisi, ona o le le lava o sela pa'epa'e. . O sela o le Myeloma e le mafai ona gaosia ni antibodies o loʻo galue ae nai lo le faia o se porotini M e mafai ona faaputuputu i totonu o le toto ma le urine, e ono faʻaleagaina ai fatugaʻo ma isi totoga, e ese mai le faʻaitiitia o le puipuiga. O se tagata soifua maloloina o loʻo maua e maua sina vaega itiiti o le M protein e taʻua e maua i le monoclonal gammopathy o le le faʻamaonia taua (MGUS), o le faʻamuamua i le tele o myeloma.
Fuafuaina o mataupu fou o le tele o myeloma i le 2022 e sili atu i le 30,000, e tusa ma le 1.8% o mataupu fou uma o le kanesa. O le fua faatatau o le ola 5-tausaga mo tagata mamaʻi e tele myeloma e tusa ma le 58% (Ref: seer.cancer.gov). Togafitiga mo le tele o le myeloma e aofia ai togafitiga e pulea ai le faʻamaʻi faʻapea foʻi ma le tausiga lagolago e faʻaleleia ai le lelei o le olaga, e pei o le faʻamalolo o faʻamaʻi ma le tausia lelei o meaʻai ma meaʻai saʻo ma faʻaopoopoga masani. O le fuafuaga o togafitiga e aofia ai le induction therapy mo le vave pulea o le kanesa; togafitiga fa'atasi ma le tele o le chemotherapy po'o le su'u ponaivi/stem cell transplant and maintenance therapy mo se vaitaimi faaumiumi e puipuia ai le toe tupu mai o le kanesa. O togafitiga e aofia ai le chemotherapy, togafitiga faʻapitoa, vailaʻau faʻamaʻi, vailaʻau faʻamaʻi, vailaʻau e suia ai ponaivi, ma le immunotherapy. O mea'ai sa'o ma mea'ai fa'alenatura e fetaui lelei ma togafitiga e mafai ona fesoasoani atili i le fa'aleleia atili o le soifua manuia ole gasegase. (Ref: https://www.cancer.net/cancer-types/multiple-myeloma/introduction; https://www.cancer.org/cancer/multiple-myeloma/about/key-statistics.html)
Taua o Mea'ai mo Mieloma Tele
O mea'ai uma ma mea'ai fa'aopoopo e aofia ai le aoina o se tasi po'o le sili atu o vaila'au fa'amalosi i vaega eseese ma aofa'i. O le gaioiga a nisi mea aoga i totonu o se mea'ai e mafai ona i ai ni feso'ota'iga leaga ae o isi mea aoga i totonu o mea'ai tutusa e mafai ona lagolago mai le tala o le Multiple Myeloma. Ole mea'ai lava e tasi e lelei ma e le-lelei gaioiga ma au'ili'iliga tu'ufa'atasiga o le a mana'omia e maua ai se fuafuaga fa'apitoa tau taumafa.
Mo se faʻataʻitaʻiga Passion Fruit e aofia ai mea aoga Vitamin C, Oleic Acid, Linolenic Acid, Linoleic Acid, Vitamin A ma isi. Ma Partridgeberry o loʻo i ai mea aoga Resveratrol, Beta-sitosterol, Stigmasterol ma isi. E foliga mai o nisi o nei mea aoga o mea'ai lava e tasi e mafai ona i ai ni a'afiaga fa'afeagai ma o lea e fautuaina ai le fa'ailoaina o mea'ai fautuaina e fa'atatau i le au'ili'iliga o mea'ai maualuga uma o lo'o i totonu o mea'ai.
Mo kanesa e pei o le Multiple Myeloma, fa'agaoioia po'o le fa'asaina o ala fa'aola kemikolo filifilia e pei o le Growth Factor Signaling, Extracellular Matrix Remodelling, RAS-RAF Signaling, MAPK Signaling e taua tele i le fa'atupuina o le kanesa. E fa'apena fo'i togafitiga 'ese'ese e galue e ala i gaioiga mole mole 'ese'ese e le tatau ona fa'aleaogaina e au mea'ai ma fa'aopoopoga. O mea'ai ma mea'ai fa'aopoopo o lo'o i ai mea aoga eseese e tofu lava ma le gaioiga mole mole i luga o ala fa'aola kemikolo eseese. O le mea lea, o le 'ai o nisi mea'ai ma mea'ai fa'aopoopo o le a fautuaina fa'atasi ma se togafitiga fa'apitoa o le Multiple Myeloma, a'o le 'ai o isi mea'ai ma mea fa'aopoopo atonu e le fautuaina.
O se tasi o mea sese masani pe a su'e mea'ai e 'ai pe leai - o le mafaufau na'o ni nai mea aoga o lo'o i totonu o mea'ai e fa'atatau i su'esu'ega i luga o le initaneti ae le amana'ia isi mea. Talu ai ona o mea aoga eseese o lo'o i totonu o mea'ai e ono i ai ni a'afiaga fa'afeagai i ala fa'aola kemikolo talafeagai - e fautuaina e iloilo uma le aofa'i maualuga o mea ga'o o lo'o iai i mea taua ma sili atu nai lo le aofa'i o mea'ai.
FAUTUAGA: IA SU'E MEA'AI FA'ATUATUA MA LE LE FA'A'OA'OINA MO LE MYELOMA E TELE - FA'AMATALAGA A'OA'O E FA'AMATALAGA O LO'O I AI I MEA'AI.
Mea'ai mo le tele o le myeloma o lo'o faia togafitiga o le chemotherapy
I le Multiple Myeloma - o genes KRAS, NRAS, TP53, BRAF ma MUC16 e maualuga le tutupu o genomic abnormalities. E le o nei kenera uma e talafeagai mo kanesa - e ui lava na lipotia mai. O nisi o nei kenera tuusa'o pe le tuusa'o e i'u ai i le fa'aogaina o ala fa'aola fa'aola e feso'otai i le kanesa. O nisi o auala e faʻatatau i avetaavale mo le Multiple Myeloma o le Growth Factor Signaling, Extracellular Matrix Remodelling, Angiogenesis ma isi. Bortezomib o se tasi o vailaʻau faʻapitoa e faʻaaogaina mo togafitiga o le kanesa. O le fa'amoemoega o togafitiga e fa'afitia pe fa'aleaogaina ai a'afiaga o fa'aola fa'aola fa'aolaola Fa'atupu Fa'ailoga Fa'ailoga, Fa'afouga o le Matrix Extracellular, Angiogenesis ina ia fa'aitiitia ai le fa'atuputeleina o fa'ama'i ma taofia ai le tuputupu a'e. O mea'ai ia o lo'o tu'ufa'atasia a latou mea aoga e lagolago ai togafitiga ma e le fa'atupuina ai fa'ama'i, o mea'ai ma mea'ai fa'aopoopo o le a aofia i mea'ai fa'apitoa. Ma fa'apena fo'i - o mea'ai ia o lo'o tu'ufa'atasia a latou mea aoga e le lagolagoina le gaioiga o togafitiga ae i'u ai ina fa'atupu fa'ama'i o le a le fautuaina i lau fuafuaga fa'apitoa tau taumafa.
FAUTUAGA: ALO'O MAI FAIGA FA'AVANOA MA MEA'AI E LE FAALAUTELEINA AI GA'OGA MO TO'AIGA KANESA MA NAIINA E FA'AMATALAGA AI FAAMA'I.
'A'ai atili fatu, Pei Mata Uliuli po'o Pigeon Pea?
O pulus o se vaega taua o le tele o taumafa. O mea aoga o loʻo i ai i le Black-eyed Pea o Vitamin C, Daidzein, Oleic Acid, Linolenic Acid, Beta-carotene ma isi. A o mea aoga o loʻo i totonu o le Pigeon Pea o Vitamin C, Oleic Acid, Linolenic Acid, Genistein, Linoleic Acid ma isi.
Vitamini C e mafai ona fa'aogaina auala fa'aola ole WNT Beta Catenin Signaling, Angiogenesis ma Hypoxia. Daidzein o loʻo i ai gaioiga faʻaola i luga o auala faʻaola PI3K-AKT-MTOR Faʻailoga, Oxidative Stress ma Endoplasmic Reticulum Stress.
E mafai e Genistein ona fa'aogaina auala fa'aola fa'aola ole Oxidative Stress. Vitamini A o lo'o iai gaioiga fa'aola i luga ole auala fa'aola ole Extracellular Matrix Remodelling. Ma faapena atu ai lava.
Pe a togafitia le Multiple Myeloma i le chemotherapy Bortezomib - O meaʻai pei o Black-eyed Pea e fautuaina pe a faʻatusatusa i le Pigeon Pea. E mafua ona o mea aoga o le Genistein ma le Vitamin A i totonu o le Pigeon Pea e fa'alavelave i gaioiga o togafitiga e ala i le fa'aleaogaina o auala olaola e galue ai le chemotherapy. E ui o mea aoga Vitamin C ma le Daidzein o loʻo i totonu o le Black-eyed Pea e lagolagoina le gaioiga o togafitiga e ala i le faʻaleleia o le ala o le biochemical auala e galue ai le chemotherapy.
FAUTUAGA: PEA BLACK-EYED PEA E FAUTUAINA IA PIGEON PEA MO LE MYELOMA E TELE I TOTOGI I LE CHEMOTHERAPY BORTEZOMIB MO NISI TUAGA.
Ai nisi fualaau faisua, Giant Butterbur po'o Ufi?
O fualaau faisua o se vaega taua o le tele o taumafa. O mea aoga o loʻo i ai i Giant Butterbur o Vitamin C, Melatonin, Beta-sitosterol, Kaempferol, Vitamin A ma isi. A o mea aoga o loʻo i totonu o le Uila o Vitamin C, Beta-sitosterol, Oleic Acid, Linolenic Acid, Dioscin ma isi.
Vitamini C e mafai ona fa'aogaina auala fa'aola ole WNT Beta Catenin Signaling, Angiogenesis ma Hypoxia. Melatonin o loʻo iai gaioiga faʻaola i luga o auala faʻaola PI3K-AKT-MTOR Faʻailoga, Faʻailoga Faʻatupu Faʻatupuina ma Faʻamaʻi Oxidative.
E mafai e le Citric Acid ona fa'aogaina auala fa'aola ole Oxidative Stress. O le Dioscin o lo'o iai gaioiga fa'aola i luga o auala fa'aola Notch Signaling. Ma faapena atu ai lava.
Pe a togafitia le Multiple Myeloma i le chemotherapy Bortezomib - Meaʻai e pei o Giant Butterbur e fautuaina pe a faʻatusatusa i le Uila. E mafua ona o mea aoga o le Citric Acid ma le Dioscin i totonu o le Uila e faʻalavelave i gaioiga o togafitiga e ala i le faʻaumatiaina o auala faʻaola o loʻo galue ai le chemotherapy. E ui o mea aoga o Vitamin C ma Melatonin o loʻo i totonu o Giant Butterbur e lagolagoina le gaioiga o togafitiga e ala i le faʻaleleia o le ala o le biochemical lea e galue ai le chemotherapy.
FAUTUAGA: GIANT BUTTERBUR E FAʻAILOA IA LE UIGA MO MULTIPLE MYELOMA I TOTOGI I LE CHEMOTHERAPY BORTEZOMIB MO NISI TUAGA.
Ua le mafai ona fa'afeso'ota'i ile MySQL: Leai se auala e talimalo ai
'A'ai atili fualaau 'aina, Partridgeberry po'o Passion Fruit?
O fua o se vaega taua o le tele o taumafa. O mea aoga o loʻo i totonu o Partridgeberry o Resveratrol, Beta-sitosterol, Stigmasterol ma isi. A o mea aoga o loʻo i totonu o le Passion Fruit o Vitamin C, Oleic Acid, Linolenic Acid, Linoleic Acid, Vitamin A ma isi.
E mafai e le Resveratrol ona faʻaogaina auala faʻapitoa o le Hypoxia, Angiogenesis ma le Endoplasmic Reticulum Stress. O le Beta-sitosterol o lo'o iai gaioiga fa'aola i luga o auala fa'aola WNT Beta Catenin Fa'ailoga, PI3K-AKT-MTOR Fa'ailoga ma Oxidative Stress.
E mafai e le Vitamini A ona fa'aogaina auala fa'aolaola ole Extracellular Matrix Remodelling. O le Citric Acid o lo'o iai ni gaioiga fa'ale-natura i luga o auala fa'aola ole Oxidative Stress. Ma faapena atu ai lava.
Pe a togafitia le Myeloma Tele ma le chemotherapy Bortezomib - O meaʻai e pei o Partridgeberry e fautuaina e faʻatusatusa i Passion Fruit. E mafua ona o mea aoga Vitamin A ma le Citric Acid i Passion Fruit e faʻalavelave i gaioiga o togafitiga e ala i le faʻaumatiaina o auala faʻaola o loʻo galue ai le chemotherapy. E ui o mea aoga Resveratrol ma Beta-sitosterol o loʻo i totonu o le Partridgeberry e lagolagoina le gaioiga o togafitiga e ala i le faʻaleleia atili o le ala o le biochemical lea e galue ai le chemotherapy.
FAUTUAGA: PARTRIDGEBERRY E FAUTUAINA IA PASSION FRUIT MO LE MYELOMA E tele I TOFIGA I LE CHEMOTHERAPY BORTEZOMIB MO NISI TUAGA.
Ai nisi nati, Chestnut po'o Macadamia Nut?
O nati o se vaega taua o le tele o taumafa. O mea aoga o loʻo i totonu o Chestnut o Quercetin, Ellagic Acid, Vitamin C, Oleic Acid, Betulin ma isi. A o mea aoga o loʻo i totonu o le Macadamia Nut o le Beta-sitosterol, Lauric Acid, Palmitic Acid, Myristic Acid, Folic Acid ma isi.
E mafai e le Ellagic Acid ona faʻaogaina auala faʻapitoa ole WNT Beta Catenin Signaling, Angiogenesis ma Extracellular Matrix Remodelling. Betulin ei ai gaioiga fa'aola i luga o auala fa'aola ole Hypoxia, Oxidative Stress ma le PI3K-AKT-MTOR Signaling.
Lauric Acid e mafai ona faʻaogaina auala faʻaola PI3K-AKT-MTOR Faʻailoga. O le Palmitic Acid o loʻo iai gaioiga faʻaola i luga o auala faʻaola WNT Beta Catenin Signaling, Angiogenesis ma Extracellular Matrix Remodelling. Ma faapena atu ai lava.
Pe a togafitia le Multiple Myeloma i le chemotherapy Bortezomib - O mea'ai pei o Chestnut e fautuaina e fa'atusatusa i le Macadamia Nut. E mafua ona o mea aoga o le Lauric Acid ma le Palmitic Acid i le Macadamia Nut e faʻalavelave i togafitiga e ala i le soloia o auala faʻaola e galue ai le chemotherapy. E ui o mea aoga ole Ellagic Acid ma Betulin o loʻo i totonu o Chestnut e lagolagoina le gaioiga o togafitiga e ala i le faʻaleleia o le ala o le biochemical auala e galue ai le chemotherapy.
FAUTUAGA: E FAUTUA LE CHESTNUT I LE MACADAMIA NUT MO LE MELELOMA MELE I TOTOGI I LE CHEMOTHERAPY BORTEZOMIB MO NISI TUAGA.
Mea'ai mo le A'afiaga o Genetic Myeloma
O se tasi o auala e iloilo ai tulaga lamatia o kanesa e ala i le siakiina o le i ai o faʻalavelave faʻaleagaina i se seti o kenera. O lo'o i ai fa'amatalaga muamua i luga o le lisi o kenera o ona suiga ma isi fa'aletonu e mafai ona i ai se sao i tulaga lamatia i kanesa eseese. O le NRAS ma le BRAF o ni kenera e lua o lo'o iai fa'alavelave e a'afia ai le Multiple Myeloma. I se tulaga e ono lamatia ai le kanesa - e ui e masani lava e leai ni togafitiga e mafai e se fomaʻi ona faʻatonuina - o auala eseese biochemical e ono faʻaosoina mole mole o le Multiple Myeloma e mafai ona faʻaaogaina e fai ma taʻiala mo le faia o se fuafuaga faʻapitoa mo meaʻai. Mo le tele o le Myeloma gene NRAS ei ai a'afiaga i luga o auala ola e pei o le G-protein-coupled Receptor Signaling, Growth Factor Signaling ma le RAS-RAF Signaling. Ma o le BRAF o loʻo i ai se aʻafiaga faʻatupu i luga o auala ola e pei o le RAS-RAF Signaling, MAPK Signaling ma Antigen Presentation. Mea'ai ma mea'ai fa'aopoopo o lo'o iai gaioiga mole mole e fa'aleaogaina ai ala fa'aola kemikolo a'afiaga o kenera pei ole NRAS ma le BRAF e tatau ona fa'aofi i totonu ole fuafuaga fa'apitoa tau taumafa. Ma o na mea'ai ma mea'ai fa'aopoopo e fa'aolaina ai a'afiaga o kenera NRAS ma le BRAF e tatau ona 'alofia.
'A'ai isi fatu pi, Mung Pipi po'o Adzuki Bean?
O mea aoga o loʻo i totonu o le Mung Bean o Quercetin, Oleic Acid, Linolenic Acid, Vitamin C, Vitexin ma isi. A o mea aoga o loʻo i totonu o le Adzuki Bean o Isoliquiritigenin, Glucaric Acid, Genistein, Folic Acid ma isi.
Quercetin e mafai ona fa'aogaina auala fa'aola ole MAPK Signaling, Cell Cycle Checkpoints ma le RAS-RAF Signaling. Vitamini C o lo'o iai gaioiga fa'ale-natura i ala fa'aola kemikolo P53 Fa'ailoga, MYC Fa'ailoga ma le PI3K-AKT-MTOR Fa'ailoga.
Ole Folic Acid e mafai ona fa'aogaina auala fa'aola ole MAPK Signaling, Cell Cycle Checkpoints ma le RAS-RAF Signaling. Ma faapena atu ai lava.
Mo fa'alavelave fa'aletagata ole Multiple Myeloma ona o fa'aletonu ile genes NRAS ma BRAF - Mea'ai e pei o le Mung Bean e fautuaina pe a fa'atusatusa ile Adzuki Bean. E mafua ona o mea aoga Folic Acid o loʻo i totonu o le Adzuki Bean e faʻateleina ai aʻafiaga o kenera i luga o ala o meaola. A'o mea aoga Quercetin ma Vitamin C o lo'o i totonu o le Mung Bean o lo'o i ai se aafiaga fa'aleaogaina o kenera i luga o auala biochemical.
FAUTUAGA: O MUNG BEAN UA FAUTUAINA IA AZUKI BEAN MO LE FAAITIITIA O LE FA'AMATALAGA O LE MELELOMA E tele ona o GENES NRAS MA BRAF.
'A'ai atili fualaau faisua, Manioka po'o Seleli?
O mea aoga o loʻo i totonu o le manioka o Beta-sitosterol, Oleic Acid, Linolenic Acid, Vitamin C, Linoleic Acid ma isi. A o mea aoga o loʻo i totonu o le Seleri o le Apigenin, Quercetin, Oleic Acid, Linolenic Acid, Vitamin C ma isi.
Vitamini C e mafai ona fa'aogaina auala fa'aola ole MAPK Signaling, Cell Cycle Checkpoints ma le RAS-RAF Signaling. O le Beta-sitosterol o lo'o iai gaioiga fa'aola i luga o auala fa'aolaola P53 Fa'ailoga, Fa'ailoga MYC ma Fa'ailoga PI3K-AKT-MTOR.
E mafai e le Luteolin ona fa'aogaina auala fa'aola ole MYC Signaling. Chrysin o loʻo iai gaioiga faʻale-natura i luga o auala faʻapitoa ole MYC Signaling. Ma faapena atu ai lava.
Mo a'afiaga fa'atupu ole Multiple Myeloma ona o fa'aletonu ile genes NRAS ma le BRAF - O mea'ai pei o Manioka e fa'atusalia ile Seleri. E mafua ona o mea aoga o le Luteolin ma Chrysin i le Seleri e faʻateleina ai aʻafiaga o kenera i luga o ala o meaola. A'o mea aoga Vitamin C ma le Beta-sitosterol o lo'o i totonu o le manioka fa'atasi e iai le a'afiaga o kenera i luga o auala fa'aola.
FAUTUAGA: E FAATUATUA LE KASASAVA I LE SELERY MO LE FA'ITIITIA O LE FA'AMATALAGA O LE MYELOMA E tele ona o GENES NRAS MA BRAF.
Meaʻai e 'ai Ina ua maeʻa faʻamaʻi kanesa!
Leai lua kanesa e tutusa. Alu i talaatu o le masani taʻiala taiala mo tagata uma ma faia filifiliga faʻapitoa e uiga i meaʻai ma faʻaopopoga ma le mautinoa.
'A'ai atili fualaau 'aina, moli po'o Strawberry?
O mea aoga o loʻo i ai i Orange o le D-limonene, Linalool, Modified Citrus Pectin, Oleic Acid, Linolenic Acid ma isi. A o mea aoga o loʻo i totonu o Strawberry o Ellagic Acid, Lupeol, Cianidanol, Beta-sitosterol, Oleic Acid ma isi.
E mafai e le D-limonene ona fa'aogaina auala fa'aola ole MAPK Signaling, Cell Cycle Checkpoints ma le RAS-RAF Signaling. Vitamini C o lo'o iai gaioiga fa'ale-natura i ala fa'aola kemikolo P53 Fa'ailoga, MYC Fa'ailoga ma le PI3K-AKT-MTOR Fa'ailoga.
E mafai e le Fisetin ona fa'aogaina auala fa'aola ole MYC Signaling. Pelargonidin o loʻo i ai gaioiga faʻale-aganuʻu i luga o auala faʻa-biochemical Suʻesuʻega o le Taʻamilosaga Cell, PI3K-AKT-MTOR Faʻailoga ma le MYC Signaling. Ma faapena atu ai lava.
Mo fa'alavelave fa'aletagata ole Multiple Myeloma ona o fa'aletonu ile genes NRAS ma le BRAF - O mea'ai pei ole Orange e fautuaina pe a fa'atusatusa ile Strawberry. E mafua ona o mea aoga Fisetin ma Pelargonidin i Strawberry e faʻateleina ai aʻafiaga o kenera i luga o auala biochemical. A'o mea aoga D-limonene ma Vitamini C o lo'o iai ile Orange fa'atasi o lo'o i ai le fa'aleaogaina ole a'afiaga o kenera ile ala fa'aola.
FAUTUAGA: ORANGE E FAATUATUA I LE STRAWBERRY MO LE FA'ITIITIA O LE FA'AMATALAGA O LE MYELOMA E tele ona o GENES NRAS MA BRAF.
'A'ai nisi nati, Almond po'o Cashew Nut?
O mea aoga o loʻo i totonu o le Almond o Quercetin, Vitamin E, Beta-sitosterol, Oleic Acid, Linolenic Acid ma isi. A'o mea aoga o lo'o i totonu o le Cashew Nut o le Palmitic Acid, Beta-sitosterol, Vitamin C, Gallic Acid, Butyric Acid ma isi.
E mafai e le Beta-sitosterol ona fa'aogaina auala fa'aolaola. Quercetin o lo'o i ai gaioiga fa'ale-natura i luga o auala fa'aola ole MAPK Fa'ailoga, RAS-RAF Fa'ailoga ma le PI53K-AKT-MTOR Fa'ailoga.
E mafai e le Palmitic Acid ona fa'aogaina auala fa'aola ole MAPK Fa'ailoga. Lauric Acid o lo'o iai gaioiga fa'aola i luga o auala fa'aola kemikolo MYC Signaling, PI3K-AKT-MTOR Signaling ma MAPK Signaling. Ma faapena atu ai lava.
Mo a'afiaga fa'atupu ole Multiple Myeloma ona o fa'aletonu ile genes NRAS ma le BRAF - O mea'ai pei ole Almond e fa'atusalia ile Cashew Nut. E mafua ona o mea aoga o le Palmitic Acid ma le Lauric Acid i Cashew Nut o loʻo faʻateleina ai aʻafiaga o kenera i luga o auala o meaola. A'o mea aoga Beta-sitosterol ma Quercetin o lo'o i totonu o le Almond fa'atasi e i ai le fa'aleaogaina o a'afiaga o kenera i luga o ala o meaola.
FAUTUAGA: ALMOND E FAATUATUA I LE CASHEW NUT MO LE FA'ITIITIA O LE FA'AMATALAGA O LE MYELOMA MULTIPLE ONA O GENES NRAS MA BRAF.
I le Aotelega
O se mea taua e manatua o lena kanesa atonu e le tutusa togafitiga mo tagata uma - ma e le tatau foi ona tutusa au mea'ai. Mea'ai e aofia ai mea'ai ma mea'ai fa'aopoopo ose meafaigaluega aoga tele e pulea e oe.
“O le a se mea e tatau ona ou ai?” ole fesili e masani ona fesiligia ile tulaga ole kanesa. Ole fa'atusatusaga ole tali e lavelave ma e fa'alagolago ile ituaiga kanesa, genomics o lo'o i lalo, togafitiga o lo'o iai nei, so'o se allergies, fa'amatalaga o le olaga, ma mea e pei ole BMI.
O le addon personalized nutrition plan e fautuaina ai mea'ai ma mea faaopoopo e fa'aitiitia ai fegalegaleaiga leaga o mea'ai ma fa'amalosia le lagolago i togafitiga.
E mafai ona e amata NEI ma fa'atulaga se fuafuaga fa'apitoa mo mea'ai mo le Multiple Myeloma e ala i le taliina o fesili ile ituaiga o kanesa, togafitiga o lo'o iai nei, fa'aopoopoga, allergies, vaitausaga, itupa, ma fa'amatalaga o le olaga.
O a meaʻai e te 'ai ma poʻo fea mea faʻaopopo e te aveina o se filifiliga e te faia. Lau filifiliga e tatau ona aofia ai le iloiloina o le kanesa gafa fesuiaʻiga, o le kanesa, faifai pea togafitiga ma faʻaopopoga, soʻo se allies, olaga faʻamatalaga, mamafa, maualuga ma masani.
O le fuafuaina meaʻai mo kanesa mai le addon e le faʻavae luga o initaneti sailiga. E otometi lava le faia o faʻaiuga mo oe faʻavae i luga o molemole faʻasaienisi faʻatinoina e o tatou saienitisi ma inisinia polokalama. Tusa lava pe e te popole e malamalama i le faʻavaeina o meaola niniʻi o le biochemical pe leai - mo le fuafuaina o meaʻai mo le kanesa e manaʻomia le malamalama.
Amata NEI i lau taumafataga fuafuaina e ala i le taliina o fesili i le igoa o le kanesa, fesuiaʻiga o gafa, togafitiga faifai pea ma supa, soʻo se allergy, masani, ituaiga olaga, tausaga kulupu ma itupa.
mau faasino
- Msk Impact 2017
- Faʻasalalau faʻasalalauga faʻapitoa i le tele o myeloma: aʻafiaga mo togafitiga faʻatatau.
- Ole vaila'au C e fa'amateina le KRAS ma le BRAF mutant sela o le kanesa colorectal e ala ile tulituliloaina o le GAPDH.
- Daidzein aafiaga i le homone refractory prostate kanesa in vitro ma in vivo faatusatusa i genistein ma soya extract: potentiation o radiotherapy.
- O le pipii i le matrix extracellular e faʻatonutonu lelei e le retinoic acid i sela HepG2.
- Resveratrol faʻaosoina le autophagy e ala i le faʻasaina saʻo o le mTOR e ala i le tauvaga ATP.
- β-Sitosterol faʻamoemoeina Trx / Trx1 reductase e faʻaoso apoptosis i sela A549 e ala i le ROS faʻasalalau mitochondrial dysregulation ma le p53 activation.
- Melatonin Fa'ato'a Fa'amalieina Lona-2, p38 MAPK, p-AKT, ma mTOR Tulaga i Ovarian Carcinoma o Ethanol-Preferring Rats.
- Aafiaga o le dioscin i luga o le faʻaleleia o le toe faʻafouina o le ate e ala i le faʻagaoioia o le ala faʻailoga Notch1 / Jagged1.
- Indeno [1,2-b] indole derivatives e avea o se vasega fou o le malosi o le protein kinase CK2 inhibitors tagata.
- Fa'asologa o fa'ama'i fatu fa'ato'a fanau mai ile Itumalo o Dallas. 1971-1984.
- Taurine e faʻaleleia ai le faʻamalosia o le inisalini e faʻaosoina i le inisalini e ala i le faʻagaoioia o le PPARγ-mTORC2 ma faʻalavelaveina le autophagy ate.
- Protein kinase ma HDAC inhibitors mai le endophytic fungus Epicoccum nigrum.
- Fa'asologa fa'asologa o le protooncogene i le toe fa'afouina o fatuga'o pe a mae'a manu'a tuga.
- O le D-Limonene e faʻaogaina le mumū, faʻamaʻi faʻamaʻi ma le auala Ras-ERK e taofia ai le tumorigenesis paʻu murine.
- Fa'ailoga tioata o se kinase 6 fa'alagolago i le tagata fa'atasi ma le flavonol inhibitor, fisetin.
- Pelargonidin taofia adipogenesis i 3T3-L1 sela e ala i le taofia o le PPAR-γ ala faailoilo.
- pharmacodynamics falema'i o antihistamines.
- Resveratrol, pterostilbene, ma piceatannol i vine tui.
- HyperFoods: Masini atamai fa'afanua o molela'au tu'i kanesa i mea'ai.
- Fisetin: o se meaʻai antioxidant mo le faʻaleleia o le soifua maloloina.
Mea'ai Fa'apitoa mo Kanesa!
E suia le kanesa i le taimi. Fa'asinomaga ma fesuia'i au mea'ai e fa'atatau i fa'ailoga o le kanesa, togafitiga, ituaiga olaga, mea'ai e fiafia i ai, allergies ma isi mea.