Ndi khansa iti yomwe ingapindule pophatikiza Sumac muzakudya zawo?

Mfundo

Sumac imadziwika kwambiri chifukwa cha thanzi lake ndipo imagwiritsidwa ntchito pafupipafupi ndi odwala khansa komanso omwe ali pachiwopsezo cha majini. Komabe, chitetezo ndi mphamvu ya Sumac kwa odwala khansa zimadalira zinthu zambiri monga kuwonetsa khansa, chemotherapy, chithandizo china, ndi chibadwa cha chotupacho. Kudziwa kuti zakudya zina ndi zowonjezera, monga manyumwa ndi sipinachi, zimatha kugwirizana bwino ndi mankhwala a khansa ndipo zimayambitsa zovuta ndizofunikira.

Zakudya ndizofunikira kwambiri pochiza khansa chifukwa zimatha kukhudza zotsatira za chithandizo. Odwala khansa ayenera kusankha mosamala komanso kuphatikiza zakudya zoyenera ndi zowonjezera m'zakudya zawo. Mwachitsanzo, Sumac ikhoza kupindulitsa iwo omwe ali ndi Primary Penile Squamous Cell Carcinoma omwe akudwala Mitomycin, koma sizingakhale zabwino kwa odwala omwe akulandira Radiation for Primary Adamantinoma. Komanso, ngakhale kuti Sumac ikhoza kuthandiza anthu omwe ali ndi chiwopsezo chamtundu wa "ERBB2", sizingaganizidwe kwa omwe ali ndi chiwopsezo chamtundu wina "CTNNB1". Kusankha zakudya zoyenera malinga ndi thanzi, chithandizo, ndi majini ndikofunikira.

Kumvetsetsa kuti kupanga chisankho pakuyenera kwa Sumac kwa wodwala khansa kuyenera kukhala payekha ndikofunikira. Zinthu zovuta monga mtundu wa khansa, njira zothandizira, mapangidwe a majini, kuopsa kwa majini, zaka, kulemera kwa thupi, ndi moyo ndizofunika kwambiri posankha ngati Sumac ndiye chisankho choyenera. Genetics ndi genomics, makamaka, ndizofunikira kwambiri. Popeza zinthuzi zimatha kusinthika, ndikofunikira kuyang'ana pafupipafupi ndikusintha zakudya kuti zigwirizane ndi kusintha kwaumoyo ndi chithandizo.

Pomaliza, njira yokwanira yosankha zakudya ndiyofunikira, kuyang'ana pa zonse zomwe zimagwira ntchito muzakudya / zowonjezera monga Sumac m'malo mowunika chilichonse chomwe chimagwira padera kapena kunyalanyaza kwathunthu. Kuwona kwakukulu uku kumalimbikitsa njira yomveka komanso yasayansi yokonzekera zakudya za khansa.

Mwachidule

Kugwiritsiridwa ntchito kwa zakudya za zomera ndi zowonjezera, monga mavitamini, zitsamba, mchere, ma probiotics, ndi zina zapadera zowonjezera, zikuwonjezeka pakati pa odwala khansa. Zowonjezera izi zidapangidwa kuti zipereke kuchuluka kwazinthu zomwe zimagwira ntchito, zambiri zomwe zimakhalanso muzakudya zosiyanasiyana. Kusakanizika ndi kusiyanasiyana kwazinthu zogwira ntchito kumasiyana pakati pazakudya zonse ndi zowonjezera. Zakudya nthawi zambiri zimapereka zinthu zingapo zogwira ntchito koma zotsika kwambiri, pomwe zowonjezera zimapereka kuchuluka kwazinthu zinazake.

Poganizira ntchito zosiyanasiyana zasayansi ndi zachilengedwe za chinthu chilichonse chomwe chimagwiritsidwa ntchito pamlingo wa mamolekyulu, ndikofunikira kuwerengera zotsatira zophatikizana za zigawozi posankha zakudya ndi zowonjezera zomwe mungadye kapena ayi.

Funso lofunikira limabuka: Kodi muyenera kuphatikiza Sumac muzakudya zanu ngati chakudya kapena chowonjezera? Kodi ndi bwino kudya Sumac ngati muli ndi chibadwa cha khansa yokhudzana ndi jini ya ERBB2? Bwanji ngati m'malo mwake chiwopsezo chanu cha majini chimachokera ku jini ya CTNNB1? Kodi ndizopindulitsa kuphatikiza Sumac muzakudya zanu ngati mwapezeka ndi Primary Adamantinoma, kapena ngati matenda anu ndi Primary Penile Squamous Cell Carcinoma? Komanso, kodi mukuyenera kusintha bwanji kumwa kwa Sumac ngati mukulandira chithandizo cha Mitomycin kapena ngati dongosolo lanu lamankhwala likuchoka ku Mitomycin kupita ku Radiation? Ndikofunika kuzindikira kuti zonena zosavuta monga 'Sumac ndi zachilengedwe, choncho zimakhala zopindulitsa nthawi zonse' kapena 'Sumac imalimbitsa chitetezo cha mthupi' ndizosakwanira pa zosankha za chakudya / zowonjezera.

Kuphatikiza apo, ndikofunikira kuti muwonenso kuyenera kophatikiza Sumac muzakudya zanu ngati pali kusintha kwamankhwala anu. Mwachidule, popanga zisankho zophatikizira zakudya kapena zowonjezera monga Sumac muzakudya zanu chifukwa cha zopindulitsa zake, muyenera kuganizira zachilengedwe chonse chazinthu zonse, poganizira zinthu monga mtundu wa khansa, machiritso omwe mukukumana nawo, ma genetic predispositions. , ndi zosankha za moyo.

Cancer

Khansara imakhalabe vuto lalikulu m'zachipatala, zomwe nthawi zambiri zimayambitsa nkhawa. Komabe, kupita patsogolo kwaposachedwa kwasintha zotsatira za chithandizo, makamaka kudzera mu njira zochizira makonda, njira zowunikira zosasokoneza pogwiritsa ntchito zitsanzo zamagazi ndi malovu, komanso chitukuko cha immunotherapy. Kuzindikira koyambirira komanso kuchitapo kanthu pa nthawi yake kwakhala kofunika kwambiri pakulimbikitsa zotsatira za chithandizo chonse.

Kuyeza kwa ma genetic kumapereka chiyembekezo chachikulu pakuwunika chiopsezo cha khansa komanso kutengeka koyambirira. Komabe, kwa anthu ambiri omwe ali ndi matenda am'banja komanso chibadwa ku khansa, njira zothandizira chithandizo, ngakhale kuyang'anitsitsa nthawi zonse, nthawi zambiri zimakhala zochepa kapena palibe. Mukapezeka ndi mtundu wina wa khansa, monga Primary Penile Squamous Cell Carcinoma kapena Primary Adamantinoma, njira zothandizira ziyenera kusinthidwa malinga ndi chibadwa cha chotupa cha munthu, siteji ya matendawa, komanso zinthu monga zaka ndi jenda. "

Pambuyo pa chithandizo, kuyang'anira kosalekeza ndikofunikira kuti muwone zizindikiro zilizonse zakuyambiranso kwa khansa ndikudziwitsanso zisankho zotsatila. Odwala ambiri omwe ali ndi khansa komanso omwe ali pachiwopsezo nthawi zambiri amafunsira upangiri wophatikizira zakudya zina ndi zowonjezera m'zakudya zawo, zomwe zimathandiza kwambiri popanga zisankho pazaumoyo.

Funso lofunika kwambiri ndilakuti mungakhale ndi chiwopsezo cha majini ndi matenda enaake a khansa posankha zakudya, monga Sumac. Kodi chiwopsezo cha chibadwa cha khansa chomwe chimachokera ku kusintha kwa ERBB2 chimakhala ndi njira yofananira ndi biochemical monga kusintha kwa CTNNB1? Kuchokera pazakudya, kodi chiopsezo chokhudzana ndi Primary Penile Squamous Cell Carcinoma chikufanana ndi Primary Adamantinoma? Kuonjezera apo, kodi kulingalira kwa zakudya kumakhalabe komweko kwa omwe akudwala Radiation monga omwe amalandira Mitomycin? Izi ndizofunikira pakusankha zakudya mwanzeru kwa anthu omwe ali ndi ziwopsezo zamitundu yosiyanasiyana komanso chithandizo cha khansa.

Sumac - Chakudya Chakudya Chowonjezera

Sumac yowonjezera imaphatikizapo zinthu zambiri zogwira ntchito, kuphatikizapo Moronic Acid, Quercitrin, Quercetin, Myrictrin ndi Myricetin, aliyense akupezeka mosiyanasiyana. Zosakaniza izi zimakhudza njira zama cell, makamaka Kukonzanso kwa DNA, Epithelial to Mesenchymal Transition, Stem Cell Signaling ndi PI3K-AKT-MTOR Signaling, yomwe imayang'anira zovuta za khansa pama cell, monga kukula kwa chotupa, kufalikira, ndi kufa kwa cell. Chifukwa cha kukhudzidwa kwachilengedwechi, kusankha zowonjezera zowonjezera monga Sumac, zokha kapena zophatikiza, zimakhala chisankho chofunikira pazakudya za khansa. Mukaganizira kugwiritsa ntchito Sumac pa khansa, ndikofunikira kuganizira izi ndi njira zosiyanasiyana. Izi zili choncho chifukwa, mofanana ndi chithandizo cha khansa, kugwiritsa ntchito Sumac si chisankho chapadziko lonse choyenera makhansa onse koma chiyenera kukhala chamunthu.

Kusankha Zowonjezera za Sumac

Kuyankha funso loti 'Ndiyenera kupewa liti Sumac pankhani ya Khansa' ndizovuta chifukwa yankho limakhala lamunthu payekhapayekha - zimangotengera 'zimadalira!'. Mofanana ndi momwe chithandizo chilichonse cha khansa sichingakhale chothandiza kwa wodwala aliyense, kufunika ndi chitetezo kapena ubwino wa Sumac zimasiyana malinga ndi momwe munthu alili. Zinthu monga mtundu wa khansa, chibadwa, chithandizo chamakono, zowonjezera zowonjezera zomwe zimatengedwa, zizoloŵezi za moyo, BMI, ndi ziwengo zilizonse zimathandizira kudziwa ngati Sumac ndi yoyenera kapena iyenera kupeŵedwa, kutsindika kufunikira kwa kulingalira kwaumwini. zisankho zotere.

1. Kodi Sumac Supplements idzathandiza Odwala a Adamantinoma omwe akulandira chithandizo cha radiation?

Adamantinoma yoyambirira imadziwika ndi kusintha kwa majini, komwe ndi ARHGAP45, PI4KB ndi SDSL, zomwe zimabweretsa kusintha kwa njira zam'magazi, makamaka Epithelial to Mesenchymal Transition ndi Inositol Phosphate Signaling. Kuchita bwino kwa chithandizo cha khansa, monga Radiation, kumadalira momwe amachitira panjira izi. Njira yoyenera imaphatikizapo kugwirizanitsa machitidwe a chithandizo ndi njira zomwe zimayendetsa khansara, potero kuonetsetsa kuti munthu ali ndi njira yoyenera komanso yothandiza. Zikatero, kupewa zakudya kapena zakudya zopatsa thanzi zomwe zitha kuthana ndi zotsatira za mankhwalawa kapena kuchepetsa kusanja kumeneku ndikofunikira. Mwachitsanzo, chowonjezera cha Sumac, chomwe chimakhudza Epithelial kupita ku Mesenchymal Transition, sichingakhale chisankho choyenera pankhani ya Primary Adamantinoma pamene akudutsa Radiation. Izi zili choncho chifukwa zikhoza kukulitsa kukula kwa matendawa kapena kusokoneza mphamvu ya mankhwala. Posankha dongosolo lazakudya, ndikofunikira kuganizira zinthu monga mtundu wa khansa, chithandizo chopitilira, zaka, jenda, BMI, moyo, ndi masinthidwe aliwonse odziwika bwino.

2. Kodi Sumac Supplements ingathandize Odwala a Primary Penile Squamous Cell Carcinoma omwe akulandira Chithandizo cha Mitomycin?

Primary Penile Squamous Cell Carcinoma imadziwika ndi kusintha kwa majini, monga ABRAXAS1, PIK3CB ndi NUP93, zomwe zimabweretsa kusintha kwa biochemical pathways, makamaka DNA Repair, Hematopoiesis ndi Inositol Phosphate Signaling. Kuchita bwino kwa chithandizo cha khansa, monga Mitomycin, kumatsimikiziridwa ndi kuyanjana kwake ndi njira izi. Cholinga chake ndikuwonetsetsa kuti chithandizocho chikugwirizana bwino ndi njira zomwe zimayendetsa khansara, ndikupangitsa njira yochizira payekha. M'nkhaniyi, zakudya kapena zowonjezera zomwe zimagwirizana ndi chithandizo kapena kupititsa patsogolo kugwirizanitsa kumeneku ziyenera kuganiziridwa. Mwachitsanzo, Sumac supplement ndi njira yabwino kwa iwo omwe ali ndi Primary Penile Squamous Cell Carcinoma akukumana ndi Mitomycin. Izi ndichifukwa choti Sumac imakhudza njira monga DNA Repair, zomwe zimatha kuletsa zinthu zomwe zimayendetsa Primary Penile Squamous Cell Carcinoma kapena kupindulitsa mphamvu ya Mitomycin.

3. Kodi Sumac Supplements Ndi Yotetezeka kwa Anthu Athanzi Amene Ali ndi CTNNB1 Mutation Associated Genetic Risk?

Makampani osiyanasiyana amapereka magulu a majini kuti awone kuopsa kwa ma genetic a mitundu yosiyanasiyana ya khansa. Maguluwa amaphatikizapo majini okhudzana ndi khansa ya m'mawere, ovarian, chiberekero, prostate, ndi khansa ya m'mimba. Kuyesa majiniwa kumatha kutsimikizira matenda ndikudziwitsa njira zamankhwala ndi kasamalidwe. Kuzindikira kusiyanasiyana komwe kumayambitsa matenda kungathandizenso kuyesa ndikuzindikira achibale omwe ali pachiwopsezo. Jini la CTNNB1 nthawi zambiri limaphatikizidwa m'magulu awa pakuwunika chiopsezo cha khansa.

Kusintha kwa jini ya CTNNB1 kumakhudza njira za biochemical kapena njira, monga Stem Cell Signaling, Adherens junction ndi Epithelial to Mesenchymal Transition, zomwe zimakhudzidwa mwachindunji kapena molakwika pakuyendetsa khansa pamlingo wa maselo. Pamene gulu la majini likuwonetsa kusintha kwa CTNNB1 komwe kumakhudzana ndi chiopsezo chowonjezereka cha Adrenocortical Carcinoma, zomveka za sayansi zimasonyeza kupeŵa kugwiritsa ntchito Sumac yowonjezera. Izi ndichifukwa choti kuwonjezera Sumac kumakhudza njira ngati Stem Cell Signaling, zomwe zitha kubweretsa zovuta pakusintha kwa CTNNB1 ndi zovuta zina za khansa.

4. Kodi Sumac Supplements Ndi Yotetezeka kwa Anthu Athanzi Amene Ali ndi ERBB2 Mutation Associated Genetic Risk?

ERBB2 imagwira ntchito yofunika kwambiri pakuwunika chiopsezo cha khansa. Kusintha kwa ERBB2 kungathe kusokoneza njira zowonongeka zowonongeka, kuphatikizapo Kukula kwa Factor Signaling ndi PI3K-AKT-MTOR Signaling, zomwe zimakhudza kukula kwa khansa. Ngati chibadwa chanu chikuwonetsa masinthidwe mu ERBB2 okhudzana ndi Esophageal Adenocarcinoma, lingalirani zophatikiza zowonjezera za Sumac mu dongosolo lanu lazakudya. Zowonjezera izi zitha kulimbikitsa njira ngati PI3K-AKT-MTOR Signaling, kupindula popereka chithandizo choyenera kwa anthu omwe ali ndi masinthidwe a ERBB2 ndi nkhawa zokhudzana ndi thanzi.

Pomaliza

Zinthu ziwiri zofunika kwambiri kukumbukira ndikuti chithandizo cha khansa ndi zakudya sizikhala zofanana kwa aliyense. Zakudya zopatsa thanzi, kuphatikiza chakudya ndi zowonjezera monga Sumac, ndi chida chothandiza chomwe chitha kuwongoleredwa ndi inu mukukumana ndi khansa.

"Ndidye chiyani?" ndi funso lomwe limafunsidwa kwambiri ndi odwala khansa komanso omwe ali pachiwopsezo cha khansa. Yankho lolondola ndiloti zimatengera zinthu monga mtundu wa khansa, chibadwa cha chotupa, chithandizo chamakono, ziwengo, moyo, ndi BMI.

Pezani makonda anu a khansa kuchokera ku addon podina ulalo womwe uli pansipa ndikuyankha mafunso okhudza mtundu wa khansa yanu, chithandizo, moyo, ziwengo, zaka, komanso jenda.

Zothandizira

• cBioPortal ya Cancer Genomics
• Myricetin imapondereza p21-activated kinase 1 m'maselo a khansa ya m'mawere a MCF-7 kupyolera mumtsinje wapansi wa njira ya β-catenin.
• cBioPortal ya Cancer Genomics
• Endonuclease ya ERCC1/XPF ndiyofunika kuti amalize kuphatikizikanso kofanana kwa mafoloko a DNA oimitsidwa ndi maulalo apakati.
• Pan-cancer kusanthula ma genomes onse.
• Chithandizo cha khansa chimapanga mawonekedwe olimba a clonal hematopoiesis.
• Kukana kwawayilesi m'maselo a khansa ya m'mawere kumalumikizidwa kudzera mu chizindikiro cha TGF-β, hybrid epithelial-mesenchymal phenotype ndi ma cell stem cell.
• Protein-tyrosine kinase inhibition: kutulukira kwa ma antitumor agents.
• [Maganizidwe ofunikira a ntchito za maphunziro apadera pokonzanso anthu olumala].