Ndi khansa iti yomwe ingapindule ndikuphatikizira Horse Chestnut muzakudya zawo?

Mfundo

Horse Chestnut imadziwika kwambiri chifukwa cha thanzi lake ndipo imagwiritsidwa ntchito pafupipafupi ndi odwala khansa komanso omwe ali pachiwopsezo cha majini. Komabe, chitetezo ndi mphamvu ya Horse Chestnut kwa odwala khansa zimadalira zinthu zambiri monga kuwonetsa khansa, chemotherapy, chithandizo china, ndi chibadwa cha chotupacho. Kudziwa kuti zakudya zina ndi zowonjezera, monga manyumwa ndi sipinachi, zimatha kugwirizana bwino ndi mankhwala a khansa ndipo zimayambitsa zovuta ndizofunikira.

Zakudya ndizofunikira kwambiri pochiza khansa chifukwa zingakhudze zotsatira za chithandizo. Odwala khansa ayenera kusankha mosamala komanso kuphatikiza zakudya zoyenera ndi zowonjezera m'zakudya zawo. Mwachitsanzo, Horse Chestnut ikhoza kupindulitsa iwo omwe ali ndi Primary Mucosal Melanoma ya Urethra omwe akudwala Doxorubicin, koma sizingakhale zabwino kwa odwala omwe akulandira Radiation for Primary Sclerosing Epithelioid Fibrosarcoma. Komanso, ngakhale Horse Chestnut ingathandize anthu omwe ali ndi chiopsezo cha chibadwa cha "CDH1", sizingaganizidwe kwa omwe ali ndi chiopsezo chosiyana ndi "ASXL1". Kusankha zakudya zoyenera malinga ndi thanzi, chithandizo, ndi majini ndikofunikira.

Kumvetsetsa kuti kupanga chisankho pakuyenera kwa Horse Chestnut kwa wodwala khansa kuyenera kukhala payekha ndikofunikira. Zinthu zovuta monga mtundu wa khansa, njira zothandizira, mapangidwe a majini, kuopsa kwa majini, zaka, kulemera kwa thupi, ndi moyo ndizofunika kwambiri posankha ngati Horse Chestnut ndiye chisankho choyenera. Genetics ndi genomics, makamaka, ndizofunikira kwambiri. Popeza zinthuzi zimatha kusinthika, ndikofunikira kuyang'ana pafupipafupi ndikusintha zakudya kuti zigwirizane ndi kusintha kwaumoyo ndi chithandizo.

Pomaliza, njira yokwanira yosankha zakudya ndiyofunikira, kuyang'ana pa zotsatira zonse zomwe zimagwira ntchito muzakudya / zowonjezera monga Horse Chestnut m'malo mowunika chilichonse chophatikizira padera kapena kunyalanyaza kwathunthu. Kuwona kwakukulu uku kumalimbikitsa njira yomveka komanso yasayansi yokonzekera zakudya za khansa.

Mwachidule

Kugwiritsiridwa ntchito kwa zakudya za zomera ndi zowonjezera, monga mavitamini, zitsamba, mchere, ma probiotics, ndi zina zapadera zowonjezera, zikuwonjezeka pakati pa odwala khansa. Zowonjezera izi zidapangidwa kuti zipereke kuchuluka kwazinthu zomwe zimagwira ntchito, zambiri zomwe zimakhalanso muzakudya zosiyanasiyana. Kusakanizika ndi kusiyanasiyana kwazinthu zogwira ntchito kumasiyana pakati pazakudya zonse ndi zowonjezera. Zakudya nthawi zambiri zimapereka zinthu zingapo zogwira ntchito koma zotsika kwambiri, pomwe zowonjezera zimapereka kuchuluka kwazinthu zinazake.

Poganizira ntchito zosiyanasiyana zasayansi ndi zachilengedwe za chinthu chilichonse chomwe chimagwiritsidwa ntchito pamlingo wa mamolekyulu, ndikofunikira kuwerengera zotsatira zophatikizana za zigawozi posankha zakudya ndi zowonjezera zomwe mungadye kapena ayi.

Funso lovuta limabuka: Kodi muyenera kuphatikiza Horse Chestnut muzakudya zanu ngati chakudya kapena chowonjezera? Kodi ndizoyenera kudya Horse Chestnut ngati muli ndi chibadwa cha khansa yokhudzana ndi jini ya CDH1? Nanga bwanji ngati m'malo mwake chiwopsezo chanu cha chibadwa chimachokera ku jini ya ASXL1? Kodi ndizopindulitsa kuphatikiza Horse Chestnut muzakudya zanu ngati mwapezeka ndi Primary Sclerosing Epithelioid Fibrosarcoma, kapena ngati matenda anu ndi Primary Mucosal Melanoma of the Urethra? Komanso, kadyedwe kanu ka Horse Chestnut kuyenera kusinthidwa bwanji ngati mukulandira chithandizo cha Doxorubicin kapena ngati dongosolo lanu lamankhwala likuchoka ku Doxorubicin kupita ku Radiation? Ndikofunika kuzindikira kuti zonena zosavuta monga 'Horse Chestnut ndi zachilengedwe, choncho zimakhala zopindulitsa nthawi zonse' kapena 'Horse Chestnut imalimbitsa chitetezo cha mthupi' ndizosakwanira pa zosankha za chakudya / zowonjezera.

Kuphatikiza apo, ndikofunikira kuti muwonenso kuyenera kwa kuphatikiza Horse Chestnut muzakudya zanu ngati pali kusintha kwamankhwala anu. Mwachidule, popanga zisankho zophatikizira zakudya kapena zowonjezera monga Horse Chestnut muzakudya zanu chifukwa cha zopindulitsa zake, muyenera kuganizira zazachilengedwe zonse zomwe zimapangidwira, poganizira zinthu monga mtundu wa khansa, chithandizo chamankhwala chomwe mukukumana nacho, majini. mayendedwe, ndi zosankha za moyo.

Cancer

Khansara imakhalabe vuto lalikulu m'zachipatala, zomwe nthawi zambiri zimayambitsa nkhawa. Komabe, kupita patsogolo kwaposachedwa kwasintha zotsatira za chithandizo, makamaka kudzera mu njira zochizira makonda, njira zowunikira zosasokoneza pogwiritsa ntchito zitsanzo zamagazi ndi malovu, komanso chitukuko cha immunotherapy. Kuzindikira koyambirira komanso kuchitapo kanthu pa nthawi yake kwakhala kofunika kwambiri pakulimbikitsa zotsatira za chithandizo chonse.

Kuyeza kwa ma genetic kumapereka chiyembekezo chachikulu pakuwunika chiopsezo cha khansa komanso kutengeka koyambirira. Komabe, kwa anthu ambiri omwe ali ndi matenda am'banja komanso chibadwa ku khansa, njira zothandizira chithandizo, ngakhale kuyang'anitsitsa nthawi zonse, nthawi zambiri zimakhala zochepa kapena palibe. Mukapezeka ndi mtundu wina wa khansa, monga Primary Mucosal Melanoma ya Urethra kapena Primary Sclerosing Epithelioid Fibrosarcoma, njira zothandizira ziyenera kusinthidwa malinga ndi chibadwa cha chotupa cha munthu, siteji ya matendawa, komanso zinthu monga zaka ndi jenda. .”

Pambuyo pa chithandizo, kuyang'anira kosalekeza ndikofunikira kuti muwone zizindikiro zilizonse zakuyambiranso kwa khansa ndikudziwitsanso zisankho zotsatila. Odwala ambiri omwe ali ndi khansa komanso omwe ali pachiwopsezo nthawi zambiri amafunsira upangiri wophatikizira zakudya zina ndi zowonjezera m'zakudya zawo, zomwe zimathandiza kwambiri popanga zisankho pazaumoyo.

Funso lofunika kwambiri ndiloti mungakhale ndi chiopsezo cha majini ndi matenda enieni a khansa posankha zakudya, monga Horse Chestnut. Kodi chiwopsezo cha chibadwa cha khansa yobwera chifukwa cha kusintha kwa CDH1 chimakhala ndi njira yofananira ndi kusintha kwa ASXL1? Kuchokera pazakudya, kodi chiopsezo chokhudzana ndi Primary Mucosal Melanoma ya Urethra chikufanana ndi Primary Sclerosing Epithelioid Fibrosarcoma? Kuphatikiza apo, kodi kulingalira kwazakudya kumakhalabe komweko kwa omwe akudwala Radiation ngati omwe amalandira Doxorubicin? Izi ndizofunikira pakusankha zakudya mwanzeru kwa anthu omwe ali ndi ziwopsezo zamitundu yosiyanasiyana komanso chithandizo cha khansa.

Horse Chestnut - Chakudya Chakudya Chowonjezera

Horse Chestnut yowonjezera imaphatikizapo zinthu zambiri zogwira ntchito, kuphatikizapo Esculin ndi Aescin, zomwe zilipo mosiyanasiyana. Zosakaniza izi zimakhudza njira zama cell, makamaka Cell Cycle Checkpoints, TGFB Signaling and Inflammation, zomwe zimayang'anira zovuta za khansa pama cell, monga kukula kwa chotupa, kufalikira, ndi kufa kwa cell. Chifukwa cha kukhudzidwa kwachilengedwechi, kusankha zowonjezera zowonjezera monga Horse Chestnut, yokha kapena kuphatikiza, kumakhala chisankho chofunikira pazakudya za khansa. Poganizira kugwiritsa ntchito Horse Chestnut kwa khansa, ndikofunikira kuganizira izi ndi njira zosiyanasiyana. Izi zili choncho chifukwa, mofanana ndi chithandizo cha khansa, kugwiritsa ntchito Horse Chestnut sichigamulo chapadziko lonse choyenera kwa makhansa onse koma chiyenera kukhala payekha.

Kusankha Zowonjezera za Horse Chestnut

Kuyankha funso loti 'Ndiyenera kupewa liti Horse Chestnut munkhani ya Cancer' ndizovuta chifukwa yankho limakhala lamunthu payekhapayekha - limangoti 'Zimadalira!'. Mofanana ndi momwe chithandizo chilichonse cha khansa sichingakhale chothandiza kwa wodwala aliyense, kufunika ndi chitetezo kapena ubwino wa Horse Chestnut zimasiyana malinga ndi momwe munthu alili. Zinthu monga mtundu weniweni wa khansa, ma genetic predispositions, chithandizo chamakono, zowonjezera zowonjezera zomwe zikumwedwa, zizolowezi za moyo, BMI, ndi ziwengo zilizonse zimathandizira kudziwa ngati Horse Chestnut ndi yoyenera kapena iyenera kupeŵedwa, kutsindika kufunika koganizira munthu payekha. muzosankha zotero.

1. Kodi Horse Chestnut Supplements idzapindula Odwala a Primary Sclerosing Epithelioid Fibrosarcoma omwe akulandira chithandizo cha radiation?

Primary Sclerosing Epithelioid Fibrosarcoma imadziwika ndi kusintha kwa majini, komwe ndi PBRM1, ATRX ndi PIK3C2G, zomwe zimabweretsa kusintha kwa njira zama biochemical, makamaka TGFB Signaling ndi Inositol Phosphate Signaling. Kuchita bwino kwa chithandizo cha khansa, monga Radiation, kumadalira momwe amachitira panjira izi. Njira yoyenera imaphatikizapo kugwirizanitsa machitidwe a chithandizo ndi njira zomwe zimayendetsa khansara, potero kuonetsetsa kuti munthu ali ndi njira yoyenera komanso yothandiza. Zikatero, kupewa zakudya kapena zakudya zopatsa thanzi zomwe zitha kuthana ndi zotsatira za mankhwalawa kapena kuchepetsa kusanja kumeneku ndikofunikira. Mwachitsanzo, Horse Chestnut supplement, yomwe imakhudza Chizindikiro cha TGFB, sichingakhale chisankho choyenera pa nkhani ya Primary Sclerosing Epithelioid Fibrosarcoma pamene akudutsa Radiation. Izi zili choncho chifukwa zikhoza kukulitsa kukula kwa matendawa kapena kusokoneza mphamvu ya mankhwala. Posankha dongosolo lazakudya, ndikofunikira kuganizira zinthu monga mtundu wa khansa, chithandizo chopitilira, zaka, jenda, BMI, moyo, ndi masinthidwe aliwonse odziwika bwino.

2. Kodi Zakudya Zamchere Za Horse Zingathandize Odwala a Urethra Omwe Akulandira Chithandizo cha Doxorubicin?

Primary Mucosal Melanoma ya Urethra imadziwika ndi kusintha kwa majini, monga TP53, SMARCA4 ndi FAT1, zomwe zimapangitsa kusintha kwa biochemical pathways, makamaka Cell Cycle Checkpoints, Apoptosis, Androgen Signaling ndi Chromatin Remodeling. Kuchita bwino kwa chithandizo cha khansa, monga Doxorubicin, kumatsimikiziridwa ndi kulumikizana kwake ndi njira izi. Cholinga chake ndikuwonetsetsa kuti chithandizocho chikugwirizana bwino ndi njira zomwe zimayendetsa khansara, ndikupangitsa njira yochizira payekha. M'nkhaniyi, zakudya kapena zowonjezera zomwe zimagwirizana ndi chithandizo kapena kupititsa patsogolo kugwirizanitsa kumeneku ziyenera kuganiziridwa. Mwachitsanzo, Horse Chestnut supplement ndi njira yabwino kwa iwo omwe ali ndi Primary Mucosal Melanoma ya Urethra omwe akukumana ndi Doxorubicin. Izi zili choncho chifukwa Horse Chestnut imakhudza njira monga Cell Cycle Checkpoints, zomwe zimatha kuletsa zinthu zomwe zimayendetsa Primary Mucosal Melanoma ya Urethra kapena kupindulitsa mphamvu ya Doxorubicin.

3. Kodi Horse Chestnut Supplements Ndiotetezeka kwa Anthu Athanzi Amene Ali ndi ASXL1 Mutation Associated Genetic Risk?

Makampani osiyanasiyana amapereka magulu a majini kuti awone kuopsa kwa ma genetic a mitundu yosiyanasiyana ya khansa. Maguluwa amaphatikizapo majini okhudzana ndi khansa ya m'mawere, ovarian, chiberekero, prostate, ndi khansa ya m'mimba. Kuyesa majiniwa kumatha kutsimikizira matenda ndikudziwitsa njira zamankhwala ndi kasamalidwe. Kuzindikira kusiyanasiyana komwe kumayambitsa matenda kungathandizenso kuyesa ndikuzindikira achibale omwe ali pachiwopsezo. Jini la ASXL1 nthawi zambiri limaphatikizidwa m'magawo awa pakuwunika chiopsezo cha khansa.

Kusintha kwa jini ya ASXL1 kumakhudza njira zama biochemical kapena njira, monga Kutupa, Oncogenic Cancer Epigenetics ndi Suppressive Histone Methylation, zomwe zimakhudzidwa mwachindunji kapena mosalunjika pakuyendetsa khansa pamlingo wa maselo. Pamene gulu la majini likuwonetsa kusintha kwa ASXL1 komwe kumakhudzana ndi chiwopsezo chowonjezereka cha Chronic Myelomonocytic Leukemia, malingaliro asayansi akuwonetsa kupeŵa kugwiritsa ntchito Horse Chestnut yowonjezera. Izi ndichifukwa choti kuwonjezera pa Horse Chestnut kumakhudza njira ngati Kutupa, komwe kumatha kubweretsa zotsatirapo zoyipa pakusintha kwa ASXL1 ndi zina zokhudzana ndi khansa.

4. Kodi Zakudya Zamchere Za Horse Ndi Zotetezeka kwa Anthu Athanzi Amene Ali ndi CDH1 Mutation Associated Genetic Risk?

CDH1 imagwira ntchito yofunika kwambiri pakuwunika chiopsezo cha khansa. Kusintha kwa CDH1 kungathe kusokoneza njira zowonongeka za biochemical, kuphatikizapo Cell Cycle Checkpoints, Adherens junction ndi Epithelial to Mesenchymal Transition, zomwe zimakhudza kukula kwa khansa. Ngati chibadwa chanu chikuwonetsa masinthidwe a CDH1 okhudzana ndi Khansa Yam'mimba, ganizirani kuphatikiza zowonjezera za Horse Chestnut mu dongosolo lanu lazakudya. Zowonjezera izi zitha kulimbikitsa njira ngati Cell Cycle Checkpoints, kupindula popereka chithandizo choyenera kwa anthu omwe ali ndi kusintha kwa CDH1 ndi nkhawa zokhudzana ndi thanzi.

Pomaliza

Zinthu ziwiri zofunika kwambiri kukumbukira ndikuti chithandizo cha khansa ndi zakudya sizikhala zofanana kwa aliyense. Zakudya, kuphatikizapo chakudya ndi zowonjezera monga Horse Chestnut, ndi chida chothandiza chomwe chingathe kulamulidwa ndi inu mukukumana ndi khansa.

"Ndidye chiyani?" ndi funso lomwe limafunsidwa kwambiri ndi odwala khansa komanso omwe ali pachiwopsezo cha khansa. Yankho lolondola ndiloti zimatengera zinthu monga mtundu wa khansa, chibadwa cha chotupa, chithandizo chamakono, ziwengo, moyo, ndi BMI.

Pezani makonda anu a khansa kuchokera ku addon podina ulalo womwe uli pansipa ndikuyankha mafunso okhudza mtundu wa khansa yanu, chithandizo, moyo, ziwengo, zaka, komanso jenda.

Zothandizira

• Kukana kwa p53 ma cell ogogoda ku doxorubicin kumakhudzana ndi kuchepetsedwa kwa mapangidwe a DNA strand breaks m'malo mosokoneza ma signature a apoptotic.
• cBioPortal ya Cancer Genomics
• Mawonekedwe osinthika a khansa ya metastatic adawululidwa kuchokera kwa odwala 10,000 omwe akuyembekezeka.
• Kukana kwawayilesi m'maselo a khansa ya m'mawere kumalumikizidwa kudzera mu chizindikiro cha TGF-β, hybrid epithelial-mesenchymal phenotype ndi ma cell stem cell.