Ndi khansa iti yomwe ingapindule ndi kuphatikiza Tiyi Wobiriwira muzakudya zawo?

Mfundo

Tiyi Wobiriwira amadziwika kwambiri chifukwa cha thanzi lake ndipo amagwiritsidwa ntchito kawirikawiri ndi odwala khansa komanso omwe ali pachiopsezo cha majini. Komabe, chitetezo ndi mphamvu ya Tiyi Wobiriwira kwa odwala khansa zimadalira zinthu zambiri monga kuwonetsa khansa, chemotherapy, chithandizo china, ndi chibadwa cha chotupacho. Kudziwa kuti zakudya zina ndi zowonjezera, monga manyumwa ndi sipinachi, zimatha kugwirizana bwino ndi mankhwala a khansa ndipo zimayambitsa zovuta ndizofunikira.

Zakudya ndizofunikira kwambiri pochiza khansa chifukwa zingakhudze zotsatira za chithandizo. Odwala khansa ayenera kusankha mosamala komanso kuphatikiza zakudya zoyenera ndi zowonjezera m'zakudya zawo. Mwachitsanzo, tiyi wobiriwira akhoza kupindulitsa iwo omwe ali ndi Chotupa Chokhazikika Chokhachokha cha Avastin, koma sichingakhale chabwino kwa odwala omwe akulandira Radiation for Primary Sinonasal Adenocarcinoma. Kuphatikiza apo, ngakhale Tiyi Yobiriwira imatha kuthandiza anthu omwe ali ndi vuto la "CDH1", sizingaganizidwe kwa omwe ali ndi chiwopsezo chosiyana "ERBB2". Kusankha zakudya zoyenera malinga ndi thanzi, chithandizo, ndi majini ndikofunikira.

Kumvetsetsa kuti kupanga chisankho pakuyenera kwa Tiyi Wobiriwira kwa wodwala khansa kuyenera kukhala payekha ndikofunikira. Zinthu zovuta monga mtundu wa khansa, njira zothandizira, mapangidwe a majini, kuopsa kwa majini, zaka, kulemera kwa thupi, ndi moyo ndizofunika kwambiri posankha ngati Tiyi Wobiriwira ndiye chisankho choyenera. Genetics ndi genomics, makamaka, ndizofunikira kwambiri. Popeza zinthuzi zimatha kusinthika, ndikofunikira kuyang'ana pafupipafupi ndikusintha zakudya kuti zigwirizane ndi kusintha kwaumoyo ndi chithandizo.

Pomaliza, njira yokwanira yosankha zakudya ndiyofunikira, kuyang'ana pa zotsatira zonse zomwe zimagwira ntchito muzakudya / zowonjezera monga Tiyi Wobiriwira m'malo mowunika chilichonse chophatikizira padera kapena kunyalanyaza kwathunthu. Kuwona kwakukulu uku kumalimbikitsa njira yomveka komanso yasayansi yokonzekera zakudya za khansa.

Mwachidule

Kugwiritsiridwa ntchito kwa zakudya za zomera ndi zowonjezera, monga mavitamini, zitsamba, mchere, ma probiotics, ndi zina zapadera zowonjezera, zikuwonjezeka pakati pa odwala khansa. Zowonjezera izi zidapangidwa kuti zipereke kuchuluka kwazinthu zomwe zimagwira ntchito, zambiri zomwe zimakhalanso muzakudya zosiyanasiyana. Kusakanizika ndi kusiyanasiyana kwazinthu zogwira ntchito kumasiyana pakati pazakudya zonse ndi zowonjezera. Zakudya nthawi zambiri zimapereka zinthu zingapo zogwira ntchito koma zotsika kwambiri, pomwe zowonjezera zimapereka kuchuluka kwazinthu zinazake.

Poganizira ntchito zosiyanasiyana zasayansi ndi zachilengedwe za chinthu chilichonse chomwe chimagwiritsidwa ntchito pamlingo wa mamolekyulu, ndikofunikira kuwerengera zotsatira zophatikizana za zigawozi posankha zakudya ndi zowonjezera zomwe mungadye kapena ayi.

Funso lofunikira limabuka: Kodi muyenera kuphatikiza Tiyi Wobiriwira muzakudya zanu ngati chakudya kapena chowonjezera? Kodi ndi bwino kudya Tiyi Wobiriwira ngati muli ndi chibadwa cha khansa yokhudzana ndi jini ya CDH1? Nanga bwanji ngati m'malo mwake chiwopsezo chanu cha chibadwa chimachokera ku jini ya ERBB2? Kodi ndizopindulitsa kuphatikiza Tiyi Wobiriwira muzakudya zanu ngati mwapezeka ndi Primary Sinonasal Adenocarcinoma, kapena ngati matenda anu ndi Primary Solitary Fibrous Tumor? Komanso, kodi mukuyenera kusintha bwanji kumwa Tiyi Wobiriwira ngati mukulandira chithandizo cha Avastin kapena ngati dongosolo lanu lamankhwala likuchoka ku Avastin kupita ku Radiation? Ndikofunika kuzindikira kuti zonena zosavuta monga 'Tiyi Wobiriwira ndi wachilengedwe, choncho nthawi zonse zimakhala zopindulitsa' kapena 'Tiyi Wobiriwira imapangitsa kuti chitetezo chitetezeke' ndizosakwanira pa zosankha za chakudya / zowonjezera.

Kuphatikiza apo, ndikofunikira kuti muwonenso kuyenera kwa kuphatikiza Tiyi Wobiriwira muzakudya zanu ngati pali kusintha kwamankhwala anu. Mwachidule, popanga zisankho zophatikizira zakudya kapena zowonjezera monga Green Tea muzakudya zanu chifukwa cha zopindulitsa zake, muyenera kuganizira momwe biochemical imakhudzira zosakaniza zonse, poganizira zinthu monga mtundu wa khansa, chithandizo chamankhwala chomwe mukukumana nacho, majini. mayendedwe, ndi zosankha za moyo.

Cancer

Khansara imakhalabe vuto lalikulu m'zachipatala, zomwe nthawi zambiri zimayambitsa nkhawa. Komabe, kupita patsogolo kwaposachedwa kwasintha zotsatira za chithandizo, makamaka kudzera mu njira zochizira makonda, njira zowunikira zosasokoneza pogwiritsa ntchito zitsanzo zamagazi ndi malovu, komanso chitukuko cha immunotherapy. Kuzindikira koyambirira komanso kuchitapo kanthu pa nthawi yake kwakhala kofunika kwambiri pakulimbikitsa zotsatira za chithandizo chonse.

Kuyeza kwa ma genetic kumapereka chiyembekezo chachikulu pakuwunika chiopsezo cha khansa komanso kutengeka koyambirira. Komabe, kwa anthu ambiri omwe ali ndi matenda am'banja komanso chibadwa ku khansa, njira zothandizira chithandizo, ngakhale kuyang'anitsitsa nthawi zonse, nthawi zambiri zimakhala zochepa kapena palibe. Akapezeka ndi mtundu wina wa khansa, monga Primary Solitary Fibrous Tumor kapena Primary Sinonasal Adenocarcinoma, njira zamankhwala ziyenera kusinthidwa malinga ndi chibadwa cha chotupa cha munthu, siteji ya matendawa, komanso zinthu monga zaka komanso jenda.

Pambuyo pa chithandizo, kuyang'anira kosalekeza ndikofunikira kuti muwone zizindikiro zilizonse zakuyambiranso kwa khansa ndikudziwitsanso zisankho zotsatila. Odwala ambiri omwe ali ndi khansa komanso omwe ali pachiwopsezo nthawi zambiri amafunsira upangiri wophatikizira zakudya zina ndi zowonjezera m'zakudya zawo, zomwe zimathandiza kwambiri popanga zisankho pazaumoyo.

Funso lofunika kwambiri ndilakuti mungakhale ndi chiopsezo cha majini ndi matenda enaake a khansa posankha zakudya, monga tiyi wobiriwira. Kodi chiwopsezo cha chibadwa cha khansa chochokera ku kusintha kwa CDH1 chimakhala ndi njira yofananira ndi biochemical monga kusintha kwa ERBB2? Kuchokera pazakudya, kodi chiopsezo chokhudzana ndi Primary Solitary Fibrous Tumor chikufanana ndi Primary Sinonasal Adenocarcinoma? Kuonjezera apo, kodi kulingalira kwa zakudya kumakhalabe komweko kwa omwe akudwala Radiation monga omwe amalandira Avastin? Izi ndizofunikira pakusankha zakudya mwanzeru kwa anthu omwe ali ndi ziwopsezo zamitundu yosiyanasiyana komanso chithandizo cha khansa.

Tiyi Wobiriwira - Chowonjezera Chakudya

Tiyi Yobiriwira Yowonjezera imaphatikizapo zinthu zambiri zogwira ntchito, kuphatikizapo Geraniin, Epigallocatechin Gallate, Epicatechin Gallate, Rutin ndi Epigallocatechin 3-(3-methylgallate), aliyense akupezeka mosiyanasiyana. Zosakaniza izi zimakhudza njira zama cell, makamaka MYC Signaling, Notch Signaling, PI3K-AKT-MTOR Signaling ndi Oncogenic Histone Methylation, yomwe imayang'anira zovuta za khansa pama cell, monga kukula kwa chotupa, kufalikira, ndi kufa kwa cell. Chifukwa cha kukhudzidwa kwachilengedwechi, kusankha zowonjezera zowonjezera monga Tiyi Wobiriwira, payekha kapena kuphatikiza, kumakhala chisankho chofunikira pazakudya za khansa. Poganizira kugwiritsa ntchito tiyi wobiriwira kwa khansa, ndikofunikira kuganizira izi ndi njira zosiyanasiyana. Izi zili choncho chifukwa, mofanana ndi chithandizo cha khansa, kugwiritsa ntchito Tiyi Wobiriwira sichigamulo chapadziko lonse chomwe chili choyenera makhansa onse koma chiyenera kukhala chamunthu.

Kusankha Zowonjezera Tiyi Wobiriwira

Kuyankha funso loti 'Ndiyenera kupewa liti tiyi wobiriwira munkhani ya khansa' ndizovuta chifukwa yankho limakhala lamunthu payekha - zimangotengera 'zimadalira!'. Mofanana ndi momwe chithandizo chilichonse cha khansa sichingakhale chothandiza kwa wodwala aliyense, kufunika ndi chitetezo kapena ubwino wa Tiyi Wobiriwira zimasiyana malinga ndi momwe munthu alili. Zinthu monga mtundu weniweni wa khansa, chibadwa, chithandizo chamakono, zowonjezera zowonjezera zomwe zimatengedwa, zizoloŵezi za moyo, BMI, ndi ziwengo zilizonse zimathandizira kudziwa ngati tiyi wobiriwira ndi woyenera kapena ayenera kupeŵedwa, kutsindika kufunika koganizira zaumwini. muzosankha zotero.

1. Kodi Green Tea Supplements idzathandiza Odwala a Primary Sinonasal Adenocarcinoma omwe akulandira chithandizo cha Radiation?

Primary Sinonasal Adenocarcinoma imadziwika ndi kusintha kwa majini, komwe ndi ATRX, NOTCH1 ndi PTPRD, zomwe zimabweretsa kusintha kwa njira zama biochemical, makamaka Notch Signaling ndi RUNX Signaling. Kuchita bwino kwa chithandizo cha khansa, monga Radiation, kumadalira momwe amachitira panjira izi. Njira yoyenera imaphatikizapo kugwirizanitsa machitidwe a chithandizo ndi njira zomwe zimayendetsa khansara, potero kuonetsetsa kuti munthu ali ndi njira yoyenera komanso yothandiza. Zikatero, kupewa zakudya kapena zakudya zopatsa thanzi zomwe zitha kuthana ndi zotsatira za mankhwalawa kapena kuchepetsa kusanja kumeneku ndikofunikira. Mwachitsanzo, chowonjezera cha Tiyi Wobiriwira, chomwe chimakhudza Chizindikiro cha Notch, sichingakhale chisankho choyenera pankhani ya Primary Sinonasal Adenocarcinoma mukakhala ndi Radiation. Izi zili choncho chifukwa zikhoza kukulitsa kukula kwa matendawa kapena kusokoneza mphamvu ya mankhwala. Posankha zakudya zoyenera, ndikofunikira kuganizira zinthu monga mtundu wa khansa, chithandizo chopitilira, zaka, jenda, BMI, moyo, ndi masinthidwe aliwonse odziwika bwino.

2. Kodi Zowonjezera Za Tiyi Wobiriwira Zingathandize Odwala Omwe Amakhala Okhazikika Omwe Amakhala Omwe Akulandira Chithandizo cha Avastin?

Chotupa Chokhazikika Chokhazikika Chokhazikika chimadziwika ndi kusintha kwa majini, monga BRD4, FLI1 ndi KMT2C, zomwe zimabweretsa kusintha kwa njira za biochemical, makamaka MYC Signaling, Chromatin Remodeling, DNA Repair, Oncogenic Histone Methylation ndi Amino Acid Metabolism. Kuchita bwino kwa chithandizo cha khansa, monga Avastin, kumatsimikiziridwa ndi kuyanjana kwake ndi njira izi. Cholinga chake ndikuwonetsetsa kuti chithandizocho chikugwirizana bwino ndi njira zomwe zimayendetsa khansara, ndikupangitsa njira yochizira payekha. M'nkhaniyi, zakudya kapena zowonjezera zomwe zimagwirizana ndi chithandizo kapena kupititsa patsogolo kugwirizanitsa kumeneku ziyenera kuganiziridwa. Mwachitsanzo, chowonjezera cha Tiyi Wobiriwira ndi njira yabwino kwa iwo omwe ali ndi Primary Solitary Fibrous Tumor omwe akukumana ndi Avastin. Izi ndichifukwa choti Tiyi Yobiriwira imakhudza njira monga MYC Signaling, yomwe imatha kuletsa zinthu zomwe zimayendetsa Primary Solitary Fibrous Tumor kapena kupindulitsa mphamvu ya Avastin.

3. Kodi Zowonjezera za Tiyi Wobiriwira Ndi Zotetezeka kwa Anthu Athanzi Amene Ali ndi ERBB2 Mutation Associated Genetic Risk?

Makampani osiyanasiyana amapereka magulu a majini kuti awone kuopsa kwa ma genetic a mitundu yosiyanasiyana ya khansa. Maguluwa amaphatikizapo majini okhudzana ndi khansa ya m'mawere, ovarian, chiberekero, prostate, ndi khansa ya m'mimba. Kuyesa majiniwa kumatha kutsimikizira matenda ndikudziwitsa njira zamankhwala ndi kasamalidwe. Kuzindikira kusiyanasiyana komwe kumayambitsa matenda kungathandizenso kuyesa ndikuzindikira achibale omwe ali pachiwopsezo. Jini la ERBB2 nthawi zambiri limaphatikizidwa m'magulu awa pakuwunika chiopsezo cha khansa.

Kusintha kwa jini ya ERBB2 kumakhudza njira za biochemical kapena njira, monga Growth Factor Signaling ndi PI3K-AKT-MTOR Signaling, zomwe zimakhudzidwa mwachindunji kapena molakwika pakuyendetsa khansa pamlingo wa maselo. Pamene gulu la majini likuwonetsa kusintha kwa ERBB2 komwe kumakhudzana ndi chiwopsezo chowonjezereka cha Esophageal Adenocarcinoma, malingaliro asayansi akuwonetsa kupeŵa kugwiritsa ntchito tiyi wobiriwira wowonjezera. Izi ndichifukwa choti kuwonjezera Tea Yobiriwira kumakhudza njira ngati PI3K-AKT-MTOR Signaling, zomwe zitha kubweretsa zotsatira zoyipa pakusintha kwa ERBB2 ndi zovuta zina za khansa.

4. Kodi Zowonjezera za Tiyi Wobiriwira Ndi Zotetezeka kwa Anthu Amene Ali ndi CDH1 Mutation Associated Genetic Risk?

CDH1 imagwira ntchito yofunika kwambiri pakuwunika chiopsezo cha khansa. Kusintha kwa CDH1 kumatha kusokoneza njira zovuta zamankhwala zamankhwala, kuphatikiza Oncogenic Histone Methylation, Adherens junction ndi Epithelial to Mesenchymal Transition, zomwe zimakhudza kukula kwa khansa. Ngati chibadwa chanu chikuwonetsa masinthidwe a CDH1 okhudzana ndi Khansa Yam'mimba, ganizirani kuphatikiza zowonjezera za Tiyi Wobiriwira mu dongosolo lanu lazakudya. Zowonjezera izi zimatha kukhudza njira monga Oncogenic Histone Methylation, kupindula popereka chithandizo choyenera kwa anthu omwe ali ndi kusintha kwa CDH1 ndi nkhawa zokhudzana ndi thanzi.

Pomaliza

Zinthu ziwiri zofunika kwambiri kukumbukira ndikuti chithandizo cha khansa ndi zakudya sizikhala zofanana kwa aliyense. Zakudya zopatsa thanzi, kuphatikiza chakudya ndi zowonjezera monga Green Tea, ndi chida chothandiza chomwe chingathe kuwongoleredwa ndi inu mukukumana ndi khansa.

"Ndidye chiyani?" ndi funso lomwe limafunsidwa kwambiri ndi odwala khansa komanso omwe ali pachiwopsezo cha khansa. Yankho lolondola ndiloti zimatengera zinthu monga mtundu wa khansa, chibadwa cha chotupa, chithandizo chamakono, ziwengo, moyo, ndi BMI.

Pezani makonda anu a khansa kuchokera ku addon podina ulalo womwe uli pansipa ndikuyankha mafunso okhudza mtundu wa khansa yanu, chithandizo, moyo, ziwengo, zaka, komanso jenda.

Zothandizira

• cBioPortal ya Cancer Genomics
• Kuponderezedwa kwa lipopolysaccharide-induced nuclear factor-kappaB ntchito ndi theaflavin-3,3'-digallate kuchokera ku tiyi wakuda ndi ma polyphenols ena kupyolera mu ndondomeko yotsika ya IkappaB kinase ntchito mu macrophages.
• cBioPortal ya Cancer Genomics
• Mawonekedwe osinthika a khansa ya metastatic adawululidwa kuchokera kwa odwala 10,000 omwe akuyembekezeka.