Ndi khansa iti yomwe ingapindule ndikuphatikiza Black Seed muzakudya zawo?

Mfundo

Black Seed imadziwika kwambiri chifukwa cha thanzi lake ndipo imagwiritsidwa ntchito pafupipafupi ndi odwala khansa komanso omwe ali pachiwopsezo cha majini. Komabe, chitetezo ndi mphamvu ya Black Seed kwa odwala khansa zimadalira zinthu zambiri monga kuwonetsa khansa, chemotherapy, chithandizo china, ndi chibadwa cha chotupacho. Kudziwa kuti zakudya zina ndi zowonjezera, monga manyumwa ndi sipinachi, zimatha kugwirizana bwino ndi mankhwala a khansa ndipo zimayambitsa zovuta ndizofunikira.

Zakudya ndizofunikira kwambiri pochiza khansa chifukwa zingakhudze zotsatira za chithandizo. Odwala khansa ayenera kusankha mosamala komanso kuphatikiza zakudya zoyenera ndi zowonjezera m'zakudya zawo. Mwachitsanzo, Black Seed ikhoza kupindulitsa iwo omwe ali ndi Primary Glioblastoma omwe akudwala Temozolomide. Kuphatikiza apo, ngakhale Mbewu Yakuda imatha kuthandiza anthu omwe ali ndi chiwopsezo chamtundu wa "TERT", sizingaganizidwe kwa iwo omwe ali ndi chiwopsezo chamtundu wina. Kusankha zakudya zoyenera malinga ndi thanzi, chithandizo, ndi majini ndikofunikira.

Kumvetsetsa kuti kupanga chisankho pakuyenera kwa Mbewu Yakuda kwa wodwala khansa kuyenera kukhala payekha ndikofunikira. Zinthu zovuta monga mtundu wa khansa, njira zothandizira, mapangidwe a majini, kuopsa kwa majini, zaka, kulemera kwa thupi, ndi moyo ndizofunika kwambiri posankha ngati Black Seed ndi chisankho choyenera. Genetics ndi genomics, makamaka, ndizofunikira kwambiri. Popeza zinthuzi zimatha kusinthika, ndikofunikira kuyang'ana pafupipafupi ndikusintha zakudya kuti zigwirizane ndi kusintha kwaumoyo ndi chithandizo.

Pomaliza, njira yokwanira yosankha zakudya ndiyofunikira, kuyang'ana pa zonse zomwe zimagwira ntchito muzakudya / zowonjezera monga Black Seed m'malo mowunika chilichonse chomwe chimagwira padera kapena kunyalanyaza kwathunthu. Kuwona kwakukulu uku kumalimbikitsa njira yomveka komanso yasayansi yokonzekera zakudya za khansa.

Mwachidule

Kugwiritsiridwa ntchito kwa zakudya za zomera ndi zowonjezera, monga mavitamini, zitsamba, mchere, ma probiotics, ndi zina zapadera zowonjezera, zikuwonjezeka pakati pa odwala khansa. Zowonjezera izi zidapangidwa kuti zipereke kuchuluka kwazinthu zomwe zimagwira ntchito, zambiri zomwe zimakhalanso muzakudya zosiyanasiyana. Kusakanizika ndi kusiyanasiyana kwazinthu zogwira ntchito kumasiyana pakati pazakudya zonse ndi zowonjezera. Zakudya nthawi zambiri zimapereka zinthu zingapo zogwira ntchito koma zotsika kwambiri, pomwe zowonjezera zimapereka kuchuluka kwazinthu zinazake.

Poganizira ntchito zosiyanasiyana zasayansi ndi zachilengedwe za chinthu chilichonse chomwe chimagwiritsidwa ntchito pamlingo wa mamolekyulu, ndikofunikira kuwerengera zotsatira zophatikizana za zigawozi posankha zakudya ndi zowonjezera zomwe mungadye kapena ayi.

Funso lofunikira limabuka: Kodi muyenera kuphatikiza Mbewu Yakuda muzakudya zanu ngati chakudya kapena chowonjezera? Kodi ndizoyenera kudya Mbewu Yakuda ngati muli ndi chibadwa cha khansa yokhudzana ndi jini ya TERT? Nanga bwanji ngati m'malo mwake chiopsezo chanu cha chibadwa chimachokera ku jini? Kodi ndizopindulitsa kuphatikiza Black Seed muzakudya zanu ngati mwapezeka ndi Primary Glioblastoma? Komanso, kudya kwanu kwa Black Seed kuyenera kusinthidwa bwanji ngati mukulandira chithandizo cha Temozolomide kapena ngati dongosolo lanu lamankhwala likuchoka ku Temozolomide? Ndikofunikira kuzindikira kuti zonena zosavuta monga 'Mbeu Yakuda ndi yachilengedwe, motero imakhala yopindulitsa nthawi zonse' kapena 'Mbeu Yakuda imalimbitsa chitetezo chathupi' sizokwanira kusankha zakudya/zowonjezera zowonjezera.

Kuphatikiza apo, ndikofunikira kuwonanso kuyenera kophatikiza Black Seed muzakudya zanu ngati pali kusintha kwamankhwala anu. Mwachidule, popanga zisankho zophatikizira zakudya kapena zowonjezera monga Black Seed muzakudya zanu chifukwa cha zopindulitsa zake, muyenera kuganizira zotsatira za biochemical pazosakaniza zonse, poganizira zinthu monga mtundu wa khansa, machiritso omwe mukukumana nawo, majini. mayendedwe, ndi zosankha za moyo.

Cancer

Khansara imakhalabe vuto lalikulu m'zachipatala, zomwe nthawi zambiri zimayambitsa nkhawa. Komabe, kupita patsogolo kwaposachedwa kwasintha zotsatira za chithandizo, makamaka kudzera mu njira zochizira makonda, njira zowunikira zosasokoneza pogwiritsa ntchito zitsanzo zamagazi ndi malovu, komanso chitukuko cha immunotherapy. Kuzindikira koyambirira komanso kuchitapo kanthu pa nthawi yake kwakhala kofunika kwambiri pakulimbikitsa zotsatira za chithandizo chonse.

Kuyeza kwa ma genetic kumapereka chiyembekezo chachikulu pakuwunika chiopsezo cha khansa komanso kutengeka koyambirira. Komabe, kwa anthu ambiri omwe ali ndi matenda am'banja komanso chibadwa ku khansa, njira zothandizira chithandizo, ngakhale kuyang'anitsitsa nthawi zonse, nthawi zambiri zimakhala zochepa kapena palibe. Akapezeka ndi mtundu wina wa khansa, monga Primary Glioblastoma, njira zochiritsira ziyenera kusinthidwa malinga ndi chibadwa cha chotupa cha munthuyo, siteji ya matendawa, komanso zinthu monga zaka ndi jenda.

Pambuyo pa chithandizo, kuyang'anira kosalekeza ndikofunikira kuti muwone zizindikiro zilizonse zakuyambiranso kwa khansa ndikudziwitsanso zisankho zotsatila. Odwala ambiri omwe ali ndi khansa komanso omwe ali pachiwopsezo nthawi zambiri amafunsira upangiri wophatikizira zakudya zina ndi zowonjezera m'zakudya zawo, zomwe zimathandiza kwambiri popanga zisankho pazaumoyo.

Funso lofunika kwambiri ndilakuti mungakhale ndi chiwopsezo cha majini ndi matenda enaake a khansa posankha zakudya, monga Black Seed. Kodi chiwopsezo cha chibadwa cha khansa yobwera chifukwa cha kusintha kwa TERT chimakhala ndi zotsatira zofanana ndi zakusintha kwa jini? Kuchokera pazakudya, kodi chiopsezo chokhudzana ndi Primary Glioblastoma chikufanana ndi khansa ina? Komanso, kodi kulingalira kwa zakudya kumakhalabe komweko kwa omwe akulandira chithandizo china monga omwe amalandira Temozolomide? Izi ndizofunikira pakusankha zakudya mwanzeru kwa anthu omwe ali ndi ziwopsezo zamitundu yosiyanasiyana komanso chithandizo cha khansa.

Mbewu Yakuda - Chowonjezera Chakudya

Chowonjezera cha Mbeu Yakuda chimaphatikizapo zinthu zingapo zomwe zimagwira ntchito, kuphatikiza Thymol, Carvacrol ndi Thymoquinone, iliyonse ilipo mosiyanasiyana. Zosakaniza izi zimakhudza njira zama cell, makamaka MAPK Signaling, Small Molecule Transport ndi Cell Cycle, yomwe imayang'anira zovuta za khansa pama cell, monga kukula kwa chotupa, kufalikira, ndi kufa kwa cell. Chifukwa cha kukhudzidwa kwachilengedwechi, kusankha zowonjezera zowonjezera monga Black Seed, zokha kapena kuphatikiza, zimakhala chisankho chofunikira pazakudya za khansa. Poganizira kugwiritsa ntchito Black Seed kwa khansa, ndikofunikira kuganizira izi ndi njira zosiyanasiyana. Izi zili choncho chifukwa, mofanana ndi chithandizo cha khansa, kugwiritsa ntchito Black Seed si chisankho chapadziko lonse choyenera makhansa onse koma chiyenera kukhala chamunthu.

Kusankha Zowonjezera Mbewu zakuda

Kuyankha funso loti 'Ndiyenera kupewa liti Mbeu Yakuda munkhani ya Khansa' ndizovuta chifukwa yankho limakhala lamunthu payekhapayekha - zimangotengera 'zimadalira!'. Mofanana ndi momwe chithandizo chilichonse cha khansa sichingakhale chothandiza kwa wodwala aliyense, kufunika ndi chitetezo kapena ubwino wa Black Seed zimasiyana malinga ndi momwe munthu alili. Zinthu monga mtundu weniweni wa khansa, chibadwa, chithandizo chamakono, zowonjezera zowonjezera zomwe zikumwedwa, zizoloŵezi za moyo, BMI, ndi zowawa zilizonse zimagwira ntchito pozindikira ngati Black Seed ndi yoyenera kapena iyenera kupeŵedwa, kutsindika kufunikira kwa kulingalira kwaumwini. muzosankha zotero.

1. Kodi Zowonjezera Mbewu zakuda zidzathandiza Odwala a Glioblastoma omwe akulandira chithandizo cha Temozolomide?

Primary Glioblastoma imadziwika ndi kusintha kwa majini, monga TRBV7-7, TAS2R46 ndi TP53, zomwe zimabweretsa kusintha kwa njira zama biochemical, makamaka MAPK Signaling, Cell Cycle Checkpoints ndi Apoptosis. Kuchita bwino kwa chithandizo cha khansa, monga Temozolomide, kumatsimikiziridwa ndi kuyanjana kwake ndi njira izi. Cholinga chake ndikuwonetsetsa kuti chithandizocho chikugwirizana bwino ndi njira zomwe zimayendetsa khansara, ndikupangitsa njira yochizira payekha. M'nkhaniyi, zakudya kapena zowonjezera zomwe zimagwirizana ndi chithandizo kapena kupititsa patsogolo kugwirizanitsa kumeneku ziyenera kuganiziridwa. Mwachitsanzo, chowonjezera cha Mbeu Yakuda ndi njira yabwino kwa iwo omwe ali ndi Primary Glioblastoma akukumana ndi Temozolomide. Izi ndichifukwa chakuti Mbewu Yakuda imakhudza njira monga MAPK Signaling, zomwe zingathe kulepheretsa zinthu zomwe zimayendetsa Primary Glioblastoma kapena kupindula ndi mphamvu ya Temozolomide.

2. Kodi Zowonjezera Mbewu zakuda Ndi Zotetezeka kwa Anthu Athanzi Amene Ali ndi TERT Mutation Associated Genetic Risk?

TERT imagwira ntchito yofunika kwambiri pakuwunika chiopsezo cha khansa. Kusintha kwa TERT kumatha kusokoneza njira zama biochemical, kuphatikiza Cell Cycle ndi DNA Repair, zomwe zimakhudza kukula kwa khansa. Ngati gulu lanu la majini likuwonetsa masinthidwe mu TERT okhudzana ndi Khansa ya Hematological, lingalirani zophatikiza zowonjezera za Black Seed mu dongosolo lanu lazakudya. Zowonjezera izi zitha kulimbikitsa njira ngati Cell Cycle, kupindula popereka chithandizo choyenera kwa anthu omwe ali ndi masinthidwe a TERT ndi nkhawa zokhudzana ndi thanzi.

Pomaliza

Zinthu ziwiri zofunika kwambiri kukumbukira ndikuti chithandizo cha khansa ndi zakudya sizikhala zofanana kwa aliyense. Zakudya zopatsa thanzi, kuphatikiza chakudya ndi zowonjezera monga Black Seed, ndi chida chothandiza chomwe chitha kuwongoleredwa ndi inu mukukumana ndi khansa.

"Ndidye chiyani?" ndi funso lomwe limafunsidwa kwambiri ndi odwala khansa komanso omwe ali pachiwopsezo cha khansa. Yankho lolondola ndiloti zimatengera zinthu monga mtundu wa khansa, chibadwa cha chotupa, chithandizo chamakono, ziwengo, moyo, ndi BMI.

Pezani makonda anu a khansa kuchokera ku addon podina ulalo womwe uli pansipa ndikuyankha mafunso okhudza mtundu wa khansa yanu, chithandizo, moyo, ziwengo, zaka, komanso jenda.

Zothandizira

• cBioPortal ya Cancer Genomics
• Cytochrome P450 ndi P-Glycoprotein-Mediated Interactions Interactions African Herbs Zosonyezedwa pa Matenda Osadziwika Odziwika.
• Kuwonetsa kwa MEK-ERK kumayang'anira mawonekedwe a DNA-repair gene MGMT ndi temozolomide kukana kwa ma cell ngati glioblastoma a stem kudzera pa MDM2-p53 axis.
• Chitowe chakuda (Nigella sativa) ndi zomwe zili (thymoquinone): ndemanga pa zotsatira za antimicrobial.
• Carvacrol imaletsa kuchulukana ndipo imapangitsa apoptosis m'maselo a khansa ya m'matumbo a anthu.
• Mawonekedwe a somatic genomic a glioblastoma.
• Carvacrol imachepetsa mayankho otupa mu nyamakazi ya nyamakazi fibroblast-monga synoviocytes.