Ndi khansa iti yomwe ingapindule pophatikiza Ashitaba muzakudya zawo?

Mfundo

Ashitaba amadziwika kwambiri chifukwa cha thanzi lake ndipo amagwiritsidwa ntchito pafupipafupi ndi odwala khansa komanso omwe ali pachiwopsezo cha majini. Komabe, chitetezo ndi mphamvu ya Ashitaba kwa odwala khansa zimadalira zinthu zambiri monga kuwonetsa khansa, chemotherapy, chithandizo china, ndi chibadwa cha chotupacho. Kudziwa kuti zakudya zina ndi zowonjezera, monga manyumwa ndi sipinachi, zimatha kugwirizana bwino ndi mankhwala a khansa ndipo zimayambitsa zovuta ndizofunikira.

Zakudya ndizofunikira kwambiri pochiza khansa chifukwa zimatha kukhudza zotsatira za chithandizo. Odwala khansa ayenera kusankha mosamala komanso kuphatikiza zakudya zoyenera ndi zowonjezera m'zakudya zawo. Mwachitsanzo, Ashitaba ikhoza kupindulitsa iwo omwe ali ndi Primary Penile Squamous Cell Carcinoma omwe akudwala Mitomycin, koma sizingakhale zabwino kwa odwala omwe akulandira Letrozole for Primary Paget matenda a bere. Kuphatikiza apo, ngakhale Ashitaba atha kuthandiza anthu omwe ali ndi chiwopsezo cha chibadwa "ALK", sizingaganizidwe kwa omwe ali ndi chiopsezo chosiyana ndi "ATM". Kusankha zakudya zoyenera malinga ndi thanzi, chithandizo, ndi majini ndikofunikira.

Kumvetsetsa kuti kupanga chisankho pakuyenera kwa Ashitaba kwa wodwala khansa kuyenera kukhala payekha ndikofunikira. Zinthu zovuta monga mtundu wa khansa, njira zothandizira, mapangidwe a majini, kuopsa kwa majini, zaka, kulemera kwa thupi, ndi moyo ndizofunika kwambiri posankha ngati Ashitaba ndiye chisankho choyenera. Genetics ndi genomics, makamaka, ndizofunikira kwambiri. Popeza zinthuzi zimatha kusinthika, ndikofunikira kuyang'ana pafupipafupi ndikusintha zakudya kuti zigwirizane ndi kusintha kwaumoyo ndi chithandizo.

Pomaliza, njira yokwanira yosankha zakudya ndiyofunikira, kuyang'ana pa zonse zomwe zimagwira ntchito muzakudya / zowonjezera monga Ashitaba m'malo mowunika chilichonse chophatikizira padera kapena kunyalanyaza kwathunthu. Kuwona kwakukulu uku kumalimbikitsa njira yomveka komanso yasayansi yokonzekera zakudya za khansa.

Mwachidule

Kugwiritsiridwa ntchito kwa zakudya za zomera ndi zowonjezera, monga mavitamini, zitsamba, mchere, ma probiotics, ndi zina zapadera zowonjezera, zikuwonjezeka pakati pa odwala khansa. Zowonjezera izi zidapangidwa kuti zipereke kuchuluka kwazinthu zomwe zimagwira ntchito, zambiri zomwe zimakhalanso muzakudya zosiyanasiyana. Kusakanizika ndi kusiyanasiyana kwazinthu zogwira ntchito kumasiyana pakati pazakudya zonse ndi zowonjezera. Zakudya nthawi zambiri zimapereka zinthu zingapo zogwira ntchito koma zotsika kwambiri, pomwe zowonjezera zimapereka kuchuluka kwazinthu zinazake.

Poganizira ntchito zosiyanasiyana zasayansi ndi zachilengedwe za chinthu chilichonse chomwe chimagwiritsidwa ntchito pamlingo wa mamolekyulu, ndikofunikira kuwerengera zotsatira zophatikizana za zigawozi posankha zakudya ndi zowonjezera zomwe mungadye kapena ayi.

Funso lovuta limabuka: Kodi muyenera kuphatikiza Ashitaba muzakudya zanu ngati chakudya kapena chowonjezera? Kodi ndizoyenera kudya Ashitaba ngati muli ndi chibadwa cha khansa yokhudzana ndi jini ya ALK? Nanga bwanji ngati m'malo mwake chiopsezo chanu cha chibadwa chimachokera ku jini ya ATM? Kodi ndizopindulitsa kuphatikiza Ashitaba muzakudya zanu ngati mwapezeka ndi matenda a Primary Paget a bere, kapena ngati matenda anu ali Primary Penile Squamous Cell Carcinoma? Komanso, kodi kumwa kwanu kwa Ashitaba kungasinthidwe bwanji ngati mukulandira chithandizo cha Mitomycin kapena ngati dongosolo lanu lamankhwala likuchoka ku Mitomycin kupita ku Letrozole? Ndikofunika kuzindikira kuti zonena zosavuta monga 'Ashitaba ndi zachilengedwe, choncho zimakhala zopindulitsa nthawi zonse' kapena 'Ashitaba imapangitsa chitetezo cha mthupi' sichikwanira kusankha zakudya kapena zowonjezera.

Kuphatikiza apo, ndikofunikira kuti muwonenso kuyenera kwa kuphatikiza Ashitaba muzakudya zanu ngati pali kusintha kwamankhwala anu. Mwachidule, popanga zisankho zophatikizira zakudya kapena zowonjezera monga Ashitaba muzakudya zanu chifukwa cha zopindulitsa zake, muyenera kuganizira momwe biochemical imakhudzira zosakaniza zonse, poganizira zinthu monga mtundu wa khansa, machiritso omwe mukukumana nawo, ma genetic predispositions. , ndi zosankha za moyo.

Cancer

Khansara imakhalabe vuto lalikulu m'zachipatala, zomwe nthawi zambiri zimayambitsa nkhawa. Komabe, kupita patsogolo kwaposachedwa kwasintha zotsatira za chithandizo, makamaka kudzera mu njira zochizira makonda, njira zowunikira zosasokoneza pogwiritsa ntchito zitsanzo zamagazi ndi malovu, komanso chitukuko cha immunotherapy. Kuzindikira koyambirira komanso kuchitapo kanthu pa nthawi yake kwakhala kofunika kwambiri pakulimbikitsa zotsatira za chithandizo chonse.

Kuyeza kwa ma genetic kumapereka chiyembekezo chachikulu pakuwunika chiopsezo cha khansa komanso kutengeka koyambirira. Komabe, kwa anthu ambiri omwe ali ndi matenda am'banja komanso chibadwa ku khansa, njira zothandizira chithandizo, ngakhale kuyang'anitsitsa nthawi zonse, nthawi zambiri zimakhala zochepa kapena palibe. Mukapezeka ndi mtundu wina wa khansa, monga Primary Penile Squamous Cell Carcinoma kapena Primary Paget matenda a bere, njira zothandizira ziyenera kusinthidwa malinga ndi chibadwa cha chotupa cha munthu, siteji ya matendawa, komanso zinthu monga zaka ndi jenda.”

Pambuyo pa chithandizo, kuyang'anira kosalekeza ndikofunikira kuti muwone zizindikiro zilizonse zakuyambiranso kwa khansa ndikudziwitsanso zisankho zotsatila. Odwala ambiri omwe ali ndi khansa komanso omwe ali pachiwopsezo nthawi zambiri amafunsira upangiri wophatikizira zakudya zina ndi zowonjezera m'zakudya zawo, zomwe zimathandiza kwambiri popanga zisankho pazaumoyo.

Funso lofunika kwambiri ndiloti mungakhale ndi chiopsezo cha majini ndi matenda enaake a khansa posankha zakudya, monga Ashitaba. Kodi chiwopsezo cha chibadwa cha khansa yobwera chifukwa cha kusintha kwa ALK chimakhala ndi zotsatira zofananira ndi kusintha kwa ATM? Kuchokera pazakudya, kodi chiopsezo chokhudzana ndi Primary Penile Squamous Cell Carcinoma chikufanana ndi Primary Paget matenda a bere? Kuonjezera apo, kodi kulingalira kwa zakudya kumakhalabe komweko kwa omwe akudwala Letrozole monga omwe amalandira Mitomycin? Izi ndizofunikira pakusankha zakudya mwanzeru kwa anthu omwe ali ndi ziwopsezo zamitundu yosiyanasiyana komanso chithandizo cha khansa.

Ashtaba - Chowonjezera Chakudya

Chowonjezera cha Ashitaba chimaphatikizapo zinthu zingapo zomwe zimagwira ntchito, kuphatikiza Isobavachalcone, iliyonse yomwe ilipo mosiyanasiyana. Zosakaniza izi zimakhudza njira zama cell, makamaka Lipid Metabolism, PI3K-AKT-MTOR Signaling ndi MAPK Signaling, yomwe imayang'anira zovuta za khansa pama cell, monga kukula kwa chotupa, kufalikira, ndi kufa kwa ma cell. Chifukwa cha kukhudzidwa kwachilengedwechi, kusankha zakudya zoyenera monga Ashitaba, yekha kapena kuphatikiza, kumakhala chisankho chofunikira pazakudya za khansa. Mukaganizira kugwiritsa ntchito Ashitaba pa khansa, ndikofunikira kuganizira izi ndi njira zosiyanasiyana. Izi zili choncho chifukwa, mofanana ndi chithandizo cha khansa, kugwiritsa ntchito Ashitaba si chisankho chapadziko lonse choyenera kwa makhansa onse koma chiyenera kukhala payekha.

Kusankha Zowonjezera za Ashitaba

Kuyankha funso loti 'Kodi ndipewe liti Ashitaba munkhani ya Khansa' ndizovuta chifukwa yankho lake ndi lamunthu payekha - zimangotengera 'zimadalira!'. Mofanana ndi momwe chithandizo chilichonse cha khansa sichingakhale chothandiza kwa wodwala aliyense, kufunika ndi chitetezo kapena ubwino wa Ashtaba zimasiyana malinga ndi momwe munthu alili. Zinthu monga mtundu weniweni wa khansa, ma genetic predispositions, chithandizo chamakono, zowonjezera zowonjezera zomwe zikumwedwa, zizolowezi za moyo, BMI, ndi ziwengo zilizonse zimathandizira kudziwa ngati Ashitaba ndi woyenera kapena ayenera kupewa, kutsindika kufunika koganizira za munthu payekha. zisankho zotere.

1. Kodi Zowonjezera za Ashitaba zidzapindula ndi matenda a Primary Paget of the breast Patients omwe akulandira chithandizo cha Letrozole?

Matenda a Primary Paget a m'mawere amadziwika ndi kusintha kwa majini, komwe ndi TTN, MUC22 ndi CCDC168, zomwe zimabweretsa kusintha kwa njira zamoyo, makamaka PI3K-AKT-MTOR Signaling. Kuchita bwino kwa chithandizo cha khansa, monga Letrozole, kumadalira momwe amachitira panjira izi. Njira yoyenera imaphatikizapo kugwirizanitsa machitidwe a chithandizo ndi njira zomwe zimayendetsa khansara, potero kuonetsetsa kuti munthu ali ndi njira yoyenera komanso yothandiza. Zikatero, kupewa zakudya kapena zakudya zopatsa thanzi zomwe zitha kuthana ndi zotsatira za mankhwalawa kapena kuchepetsa kusanja kumeneku ndikofunikira. Mwachitsanzo, chithandizo cha Ashitaba, chomwe chimakhudza PI3K-AKT-MTOR Signaling, sichingakhale chisankho choyenera pa matenda a Primary Paget a m'mawere pamene akudwala Letrozole. Izi zili choncho chifukwa zikhoza kukulitsa kukula kwa matendawa kapena kusokoneza mphamvu ya mankhwala. Posankha dongosolo lazakudya, ndikofunikira kuganizira zinthu monga mtundu wa khansa, chithandizo chopitilira, zaka, jenda, BMI, moyo, ndi masinthidwe aliwonse odziwika bwino.

2. Kodi Zowonjezera za Ashitaba Zingapindule Odwala a Primary Penile Squamous Cell Carcinoma Omwe Akulandira Chithandizo cha Mitomycin?

Primary Penile Squamous Cell Carcinoma imadziwika ndi kusintha kwa majini, monga ABRAXAS1, PIK3CB ndi NUP93, zomwe zimabweretsa kusintha kwa biochemical pathways, makamaka Lipid Metabolism, Hematopoiesis ndi Inositol Phosphate Signaling. Kuchita bwino kwa chithandizo cha khansa, monga Mitomycin, kumatsimikiziridwa ndi kuyanjana kwake ndi njira izi. Cholinga chake ndikuwonetsetsa kuti chithandizocho chikugwirizana bwino ndi njira zomwe zimayendetsa khansara, ndikupangitsa njira yochizira payekha. M'nkhaniyi, zakudya kapena zowonjezera zomwe zimagwirizana ndi chithandizo kapena kupititsa patsogolo kugwirizanitsa kumeneku ziyenera kuganiziridwa. Mwachitsanzo, chowonjezera cha Ashitaba ndi njira yabwino kwa iwo omwe ali ndi Primary Penile Squamous Cell Carcinoma akukumana ndi Mitomycin. Izi ndichifukwa choti Ashitaba imakhudza njira monga Lipid Metabolism, zomwe zimatha kuletsa zinthu zomwe zimayendetsa Primary Penile Squamous Cell Carcinoma kapena kupindulitsa mphamvu ya Mitomycin.

3. Kodi Zowonjezera za Ashitaba Ndi Zotetezeka kwa Anthu Athanzi Amene Ali ndi ATM Mutation Associated Genetic Risk?

Makampani osiyanasiyana amapereka magulu a majini kuti awone kuopsa kwa ma genetic a mitundu yosiyanasiyana ya khansa. Maguluwa amaphatikizapo majini okhudzana ndi khansa ya m'mawere, ovarian, chiberekero, prostate, ndi khansa ya m'mimba. Kuyesa majiniwa kumatha kutsimikizira matenda ndikudziwitsa njira zamankhwala ndi kasamalidwe. Kuzindikira kusiyanasiyana komwe kumayambitsa matenda kungathandizenso kuyesa ndikuzindikira achibale omwe ali pachiwopsezo. Jini la ATM nthawi zambiri limaphatikizidwa m'magawo awa pakuwunika chiopsezo cha khansa.

Kusintha kwa jini ya ATM kumakhudza njira zama biochemical kapena njira, monga PI3K-AKT-MTOR Signaling ndi DNA Repair, zomwe zimakhudzidwa mwachindunji kapena mosalunjika pakuyendetsa khansa pamlingo wa maselo. Pamene gulu la majini likuwonetsa kusintha kwa ATM komwe kumakhudzana ndi chiopsezo chowonjezereka cha Chronic Myelomonocytic Leukemia, zomveka za sayansi zimasonyeza kupeŵa kugwiritsa ntchito Ashitaba. Izi ndichifukwa choti kuwonjezera kwa Ashitaba kumakhudza njira ngati PI3K-AKT-MTOR Signaling, zomwe zitha kubweretsa zovuta pakusintha kwa ATM ndi zina zokhudzana ndi khansa.

4. Kodi Zowonjezera za Ashitaba Ndi Zotetezeka kwa Anthu Athanzi Amene Ali ndi ALK Mutation Associated Genetic Risk?

ALK imagwira ntchito yofunika kwambiri pakuwunika chiopsezo cha khansa. Kusintha kwa ALK kumatha kusokoneza njira zovuta zama biochemical, kuphatikiza MAPK Signaling ndi Growth Factor Signaling, zomwe zimakhudza kukula kwa khansa. Ngati gulu lanu la majini likuwonetsa kusintha kwa ALK komwe kumalumikizidwa ndi Central Nervous System, lingalirani zophatikiza zowonjezera za Ashitaba mu dongosolo lanu lazakudya. Zowonjezera izi zimatha kukhudza njira ngati MAPK Signaling, kupindula popereka chithandizo choyenera kwa anthu omwe ali ndi kusintha kwa ALK ndi nkhawa zokhudzana ndi thanzi.

Pomaliza

Zinthu ziwiri zofunika kwambiri kukumbukira ndikuti chithandizo cha khansa ndi zakudya sizikhala zofanana kwa aliyense. Zakudya zopatsa thanzi, kuphatikiza zakudya ndi zowonjezera monga Ashitaba, ndi chida chothandiza chomwe chingathe kuwongoleredwa ndi inu mukukumana ndi khansa.

"Ndidye chiyani?" ndi funso lomwe limafunsidwa kwambiri ndi odwala khansa komanso omwe ali pachiwopsezo cha khansa. Yankho lolondola ndiloti zimatengera zinthu monga mtundu wa khansa, chibadwa cha chotupa, chithandizo chamakono, ziwengo, moyo, ndi BMI.

Pezani makonda anu a khansa kuchokera ku addon podina ulalo womwe uli pansipa ndikuyankha mafunso okhudza mtundu wa khansa yanu, chithandizo, moyo, ziwengo, zaka, komanso jenda.

Zothandizira

• cBioPortal ya Cancer Genomics
• Anti-kutupa ndi anticholinesterase ntchito ya ma flavonoid asanu ndi limodzi otalikirana ndi mitundu ya Polygonum ndi Dorstenia.
• Chithandizo cha khansa chimapanga mawonekedwe olimba a clonal hematopoiesis.
• Isobavachalcone yotalikirana ndi Psoralea corylifolia imalepheretsa kukula kwa maselo ndipo imapangitsa kuti apoptosis iwonongeke poletsa njira ya AKT/GSK-3β/β-catenin m'maselo a khansa ya colorectal.
• Isobavachalcone imakhala ndi anti-proliferative and pro-apoptotic zotsatira pa maselo a khansa ya chiwindi cha munthu poyang'ana njira yowonetsera ERKs / RSK2.
• Imani ndi khansa ya Ib yophunzira ya pan-phosphoinositide-3-kinase inhibitor buparlisib yokhala ndi letrozole mu estrogen receptor-positive/human epidermal growth factor receptor 2-negative metastatic breast cancer.
• [Cyclooxygenase-2 mawu m'maselo a khansa ya esophageal ndi kulowetsedwa ndi mitomycin C].