Zakudya za Gliosarcoma!

Introduction

Zakudya za Gliosarcoma ziyenera kukhala zamunthu payekhapayekha komanso ziyenera kusinthidwa ndi chithandizo cha khansa kapena kusintha kwa chibadwa cha chotupa. Kusintha kwamunthu ndikusintha kuyenera kuganizira zonse zomwe zimagwira ntchito kapena ma bioactive omwe ali muzakudya zosiyanasiyana molingana ndi biology ya khansa, majini, chithandizo, moyo komanso zomwe amakonda. Chifukwa chake ngakhale zakudya ndi chimodzi mwazosankha zofunika kwambiri kwa wodwala khansa komanso munthu yemwe ali pachiwopsezo cha khansa - momwe angasankhire zakudya zomwe angadye si ntchito yophweka.

Gliosarcoma, chotupa muubongo chosowa kwambiri komanso chowopsa chomwe nthawi zambiri chimatengedwa ngati mtundu wina wa glioblastoma, chili ndi mawonekedwe ake apadera komanso azachipatala. Mafotokozedwe a matenda a gliosarcoma amawulula kuphatikiza kwa zinthu za glial ndi sarcomatous, kuzisiyanitsa ndi glioblastoma. Radiology, makamaka MRI, imagwira ntchito yofunika kwambiri pakuzindikira matenda, kuwonetsa mawonekedwe apadera azithunzi. Zizindikiro za gliosarcoma ndizofanana ndi zotupa zina za muubongo, kuphatikiza mutu, khunyu, ndi kuperewera kwaubongo. Kutalika kwa moyo komanso kuneneratu kwa odwala gliosarcoma nthawi zambiri kumakhala kocheperako, kupulumuka kutengera zinthu zosiyanasiyana monga komwe chotupacho komanso thanzi la wodwalayo. Khodi ya ICD-10 ya gliosarcoma imayika magawo ake muzolemba zamankhwala. Kumvetsetsa zomwe zimayambitsa gliosarcoma ikadali nkhani yopitilira kafukufuku. Chithandizo chimaphatikizapo opaleshoni, chemotherapy, ndi radiotherapy, koma mphamvu zake zimatha kusiyana. Zokumana nazo za opulumuka a gliosarcoma zimapereka chidziwitso chofunikira pakukhala ndi vutoli. Kuyika kwa gliosarcoma, kofunika kwambiri pokonzekera chithandizo, kumatsatira malangizo a WHO 2021, omwe nthawi zambiri amatchulidwa kuti IDH-wildtype WHO grade 4, kusonyeza khalidwe lawo laukali. Chisamaliro chakumapeto kwa moyo ndi chofunikira kwambiri pazigawo zapamwamba, kuyang'ana pa kayendetsedwe ka zizindikiro ndi khalidwe la moyo. Kuwongolera kwathunthu kwa gliosarcoma kumafunikira njira zosiyanasiyana, kuphatikizira kafukufuku waposachedwa ndi njira zamankhwala kuti zithandizire zotulukapo za omwe akhudzidwa ndi chotupa chaubongo chovutachi.

Kwa Gliosarcoma, kodi zili ndi masamba, zipatso, mtedza, mbewu zomwe munthu amadya?

Funso lodziwika bwino lazakudya lomwe limafunsidwa ndi odwala khansa komanso anthu omwe ali pachiwopsezo cha khansa ndi - la khansa ngati Gliosarcoma kodi zilibe kanthu kuti ndi zakudya ziti zomwe ndimadya komanso zomwe sindidya? Kapena ngati nditsatira zakudya zochokera ku zomera ndizokwanira khansa ngati Gliosarcoma?

Mwachitsanzo, kodi zilibe kanthu ngati Kolifulawa wamasamba amadyedwa kwambiri poyerekeza ndi anyezi a Wales? Kodi pamakhala kusiyana kulikonse ngati zipatso za Pummelo zimakondedwa kuposa Grapefruit/pummelo Hybrid? Komanso ngati kusankha kofananako kumapangidwira mtedza/mbewu monga Butternut pamwamba pa Pili Nut komanso zamasamba monga Adzuki Bean pa Catjang Pea. Ndipo ngati zomwe ndimadya zili ndi vuto - ndiye kuti munthu angadziwe bwanji zakudya zomwe zimalimbikitsidwa ndi Gliosarcoma ndipo ndi yankho lomwelo kwa aliyense yemwe ali ndi matenda omwewo kapena chiwopsezo cha majini?

Inde! Zakudya zomwe mumadya ndizofunikira pa Gliosarcoma!

Malingaliro a zakudya sangakhale ofanana kwa aliyense ndipo akhoza kukhala osiyana ngakhale pa matenda omwewo komanso chiopsezo cha majini.

Zakudya zonse (masamba, zipatso, mtedza, mbewu, phala, mafuta ndi zina) ndi zakudya zopatsa thanzi zimapangidwa ndi mamolekyulu opitilira imodzi kapena zogwira ntchito mosiyanasiyana komanso kuchuluka kwake. Chilichonse chogwiritsidwa ntchito chimakhala ndi njira yapadera yochitirapo kanthu - yomwe imatha kuyambitsa kapena kuletsa njira zosiyanasiyana zama biochemical. Zakudya zongotchulidwa mwachidule ndi zowonjezera zomwe zimalimbikitsidwa ndizomwe sizimayambitsa kuchuluka kwa maselo oyambitsa khansa koma zimawachepetsa. Apo ayi zakudya zimenezo siziyenera kuvomerezedwa. Zakudya zimakhala ndi zosakaniza zingapo zomwe zimagwira ntchito - chifukwa chake powunika zakudya ndi zowonjezera, muyenera kuganizira momwe zosakaniza zonse zimakhudzira thupi limodzi osati payekhapayekha.

Mwachitsanzo Pummelo ili ndi zinthu zogwira ntchito Quercetin, Curcumin, Apigenin, Caffeine, Lupeol. Ndipo Grapefruit/pummelo Hybrid ili ndi zosakaniza zogwira ntchito Curcumin, Apigenin, Caffeine, Lupeol, Lycopene ndipo mwina ena.

Kulakwitsa kofala komwe kumachitika posankha ndikusankha zakudya zoyenera kudya za Gliosarcoma - ndikuwunika zomwe zasankhidwa zokha zomwe zili muzakudya ndikunyalanyaza zina. Chifukwa zosakaniza zosiyanasiyana zomwe zili muzakudya zitha kukhala ndi zotsatira zotsutsana ndi oyendetsa khansa - simungathe kusankha zosakaniza muzakudya ndi zowonjezera kuti mupange chisankho chazakudya cha Gliosarcoma.

INDE - ZOSANKHA CHAKUDYA NDINKHANI PA KANSA. ZINSINSI ZA KALERE ZIYENERA KUGANIZIRA ZONSE ZONSE ZOKHUDZA ZOKHUDZA ZAKUDYA.

Maluso Ofunika Pakukonda Chakudya Mwamakonda a Gliosarcoma?

Zakudya zamakhansa ngati Gliosarcoma zimakhala ndi zakudya / zowonjezera; zakudya zosavomerezeka / zowonjezera zomwe zili ndi maphikidwe achitsanzo omwe amaika patsogolo kugwiritsa ntchito zakudya zoyenera. Chitsanzo cha kadyedwe kake kamakonda kuwoneka pa izi kugwirizana.

Kusankha zakudya zomwe zikulimbikitsidwa kapena ayi ndizovuta kwambiri, zomwe zimafuna ukadaulo wa Gliosarcoma biology, sayansi yazakudya, majini, biochemistry komanso kumvetsetsa bwino momwe chithandizo cha khansa chimagwirira ntchito komanso zovuta zina zomwe chithandizocho chingasiye kugwira ntchito.

ZOCHEPA ZODZIWA ZOCHEPA ZOFUNIKA KUTI MUZITHANDIZA KUKHALA KWA MANKHWALA A KANSA NDI: CANCER BIOLOGY, FOOD SAYANSI, MANKHWALA A KANSA NDI MA GENETICS.

Makhalidwe a khansa ngati Gliosarcoma

Makhansa onse ngati Gliosarcoma amatha kudziwika ndi njira zapadera za biochemical - njira zosayina za Gliosarcoma. Njira zama biochemical monga TWEAK Signaling, Growth Factor Signaling, PI3K-AKT-MTOR Signaling, Apoptosis ndi gawo la tanthauzo la siginecha ya Gliosarcoma. Mitundu ya khansa ya munthu aliyense imatha kukhala yosiyana chifukwa chake siginecha yawo yeniyeni ya khansa imatha kukhala yapadera.

Chithandizo chomwe chili chothandiza kwa Gliosarcoma chiyenera kuzindikirika ndi ma signature a biochemical omwe amalumikizana nawo kwa wodwala khansa aliyense komanso munthu yemwe ali pachiwopsezo cha majini. Choncho mankhwala osiyanasiyana omwe ali ndi njira zosiyanasiyana zochitira zinthu ndi othandiza kwa odwala osiyanasiyana. Momwemonso komanso pazifukwa zomwezo zakudya ndi zowonjezera ziyenera kukhala zamunthu aliyense payekhapayekha. Chifukwa chake zakudya zina ndi zowonjezera zimalimbikitsidwa kwa Gliosarcoma mukamamwa mankhwala a khansa ya Temozolomide, ndipo zakudya zina ndi zowonjezera sizovomerezeka.

Magwero ngati cBioPortal ndipo ena ambiri amapereka deta yosadziwika ya odwala omwe ali ndi chiwerengero cha anthu omwe amachokera ku mayesero a zachipatala pa zizindikiro zonse za khansa. Izi zili ndi tsatanetsatane wa kafukufuku wazachipatala monga kukula kwa zitsanzo / kuchuluka kwa odwala, magulu azaka, jenda, fuko, chithandizo, malo otupa ndi masinthidwe aliwonse.

TP53, TERT, BRAF, RB1 ndi PTEN ndi omwe ali pamwamba pa jini za Gliosarcoma. TP53 imanenedwa mu 9.1% ya odwala oyimira m'mayesero onse azachipatala. Ndipo TERT imanenedwa mu 9.1%. Deta yophatikizidwa ya odwala imaphimba zaka zapakati pa 52 mpaka 80. 50.0 % ya data ya odwala amadziwika kuti ndi amuna. Biology ya Gliosarcoma pamodzi ndi ma genetics omwe adanenedwa palimodzi amafotokozera kuchuluka kwazomwe zimayimiridwa ndi njira zama biochemical za khansa iyi. Ngati chibadwa cha khansa ya munthu kapena majini omwe amathandizira pachiwopsezo amadziwikanso ndiye kuti ayenera kugwiritsidwanso ntchito pakusintha zakudya.

ZOSANKHA ZA KALERE ZIYENERA KUGWIRITSA NTCHITO NDI SIZINI YA KANSA YA MUNTHU ALIYENSE.

Zakudya ndi Zowonjezera za Gliosarcoma

Kwa Odwala Khansa

Odwala khansa omwe ali ndi chithandizo chamankhwala kapena ochepetsa chithandizo chamankhwala amayenera kupanga zisankho pazakudya ndi zowonjezera - pazakudya zopatsa thanzi, kuthana ndi zovuta zilizonse komanso kuwongolera kasamalidwe ka khansa. Zakudya zonse zozikidwa pamasamba sizofanana ndipo kusankha ndikuyika patsogolo zakudya zomwe zimasankhidwa payekhapayekha komanso zomwe zimasinthidwa kuti zigwiritsidwe ntchito ndi khansa ndizofunikira komanso zovuta. Nazi zitsanzo zopereka malangizo opangira zisankho za kadyedwe.

Sankhani masamba a CAULIFLOWER kapena WELSH anyanisi?

Kolifulawa wamasamba ali ndi zinthu zambiri zogwira ntchito kapena bioactives monga Curcumin, Lupeol, Delphinidin, Daidzein, Brassinin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Angiogenesis, P53 Signaling, NFKB Signaling ndi PI3K-AKT-MTOR Signaling ndi ena. Kolifulawa akulimbikitsidwa kwa Gliosarcoma pamene chithandizo cha khansa chopitilira ndi Temozolomide. Izi ndichifukwa choti Kolifulawa amasintha njira zama biochemical zomwe zanenedwa mwasayansi kuti zidziwitse zotsatira za Temozolomide.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu masamba a Welsh anyezi ndi Curcumin, Caffeine, Lupeol, Lycopene, Delphinidin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga NFKB Signaling ndi ena. Anyezi a ku Welsh sakuvomerezedwa kwa Gliosarcoma pamene chithandizo cha khansa chikupitirirabe ndi Temozolomide chifukwa chimasintha njira zomwe zimapangitsa kuti chithandizo cha khansa chisagwirizane kapena chisamayankhe.

CAULIFLOWER YA MASABATA AMAKONZEDWA PA WELSH ANYESI WA Gliosarcoma NDI MANKHWALA A Temozolomide.

Sankhani Chipatso GRAPEFRUIT/PUMMELO HYBRID kapena PUMMELO?

Zipatso za Grapefruit/pummelo Hybrid zili ndi zinthu zambiri zogwira ntchito kapena bioactives monga Curcumin, Apigenin, Caffeine, Lupeol, Lycopene. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga kukonza DNA, TGFB Signaling, NFKB Signaling ndi PI3K-AKT-MTOR Signaling ndi ena. Grapefruit/pummelo Hybrid ikulimbikitsidwa kwa Gliosarcoma pamene chithandizo cha khansa chopitilira ndi Temozolomide. Izi zili choncho chifukwa Grapefruit/pummelo Hybrid imasintha njira za biochemical zomwe zanenedwa mwasayansi kuti zidziwitse zotsatira za Temozolomide.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu zipatso Pummelo ndi Quercetin, Curcumin, Apigenin, Caffeine, Lupeol. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga kukonza DNA ndi TGFB Signaling ndi ena. Pummelo sivomerezedwa kwa Gliosarcoma pamene chithandizo cha khansa chikupitirirabe ndi Temozolomide chifukwa chimasintha njira za biochemical zomwe zimapangitsa kuti chithandizo cha khansa chisagwirizane kapena chisamayankhe.

ZIPATSO ZA GRAPEFRUIT/PUMMELO HYBRID AMAKONZEDWA PA PUMMELO PA Gliosarcoma NDI MACHIRETO Temozolomide.

Sankhani Nut BUTTERNUT kapena PILI NUT?

Butternut imakhala ndi zinthu zambiri zogwira ntchito kapena bioactives monga Curcumin, Apigenin, Caffeine, Lupeol, Lycopene. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga kukonza DNA, MYC Signaling, NFKB Signaling ndi PI3K-AKT-MTOR Signaling ndi ena. Butternut akulimbikitsidwa kwa Gliosarcoma pamene chithandizo cha khansa chikupitirirabe ndi Temozolomide. Izi ndichifukwa choti Butternut imasintha njira zama biochemical zomwe zanenedwa mwasayansi kuti zidziwitse zotsatira za Temozolomide.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu Pili Nut ndi Curcumin, Apigenin, Caffeine, Lupeol, Lycopene. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga kukonza DNA ndi TGFB Signaling ndi ena. Pili Nut sizovomerezeka kwa Gliosarcoma pamene chithandizo cha khansa chikupitirirabe ndi Temozolomide chifukwa chimasintha njira za biochemical zomwe zimapangitsa kuti chithandizo cha khansa zisawonongeke kapena kuti chisamayankhe.

BUTTERNUT AMAKONZEDWA PA NTHAWI YA PILI PA Gliosarcoma NDI MACHITIDWE A Temozolomide.

Kwa Anthu Amene Ali ndi Genetic Risk of Cancer

Funso lofunsidwa ndi anthu omwe ali ndi chiwopsezo cha chibadwa cha Gliosarcoma kapena mbiri yabanja ndi "Kodi Ndiyenera Kudya Chiyani Mosiyana ndi Kale?" ndi momwe angasankhire zakudya ndi zowonjezera kuti athe kuthana ndi kuopsa kwa matendawa. Popeza pachiwopsezo cha khansa palibe chomwe chingachitike pankhani ya chithandizo - zosankha zazakudya ndi zowonjezera zimakhala zofunika komanso chimodzi mwazinthu zochepa zomwe zingatheke. Zakudya zonse zochokera ku zomera sizofanana ndipo zimatengera chibadwa chodziwika ndi siginecha ya njira - zosankha za zakudya ndi zowonjezera ziyenera kukhala zaumwini.

Sankhani Masamba GIANT BUTTERBUR kapena BLACK KABIJI?

Masamba a Giant Butterbur ali ndi zinthu zambiri zogwira ntchito kapena bioactives monga Apigenin, Curcumin, Lupeol, Formononetin, Daidzein. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Kuzindikiritsa kwa MAPK, Kukonza kwa DNA, Kuyika Ma cell Stem ndi PI3K-AKT-MTOR Signaling ndi ena. Giant Butterbur ikulimbikitsidwa kuti ikhale pachiwopsezo cha Gliosarcoma pomwe chiwopsezo chokhudzana ndi majini ndi BRAF. Izi ndichifukwa choti Giant Butterbur imakulitsa njira za biochemical zomwe zimatsutsana ndi oyendetsa siginecha ake.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu masamba a Black Kabichi ndi Apigenin, Curcumin, Lupeol, Formononetin, Daidzein. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Oncogenic Cancer Epigenetics ndi Stem Cell Signaling ndi ena. Kabichi wakuda ndi osavomerezeka pamene chiopsezo cha Gliosarcoma pamene chiwopsezo cha majini ndi BRAF chifukwa chimawonjezera njira zake.

MANKHWALA WABWINO WA MASWERO AKUTHANDIZANI PA KABIJI WAKUDA PA BRAF GENETIC RISK OF CANCER.

Sankhani Chipatso NANCE kapena ACEROLA?

Zipatso za Nance zili ndi zinthu zambiri zogwira ntchito kapena bioactives monga Apigenin, Curcumin, Lupeol, Formononetin, Daidzein. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Kuzindikiritsa kwa MAPK, Kukonza kwa DNA, Kuyika Ma cell Stem ndi PI3K-AKT-MTOR Signaling ndi ena. Nance akulimbikitsidwa pachiwopsezo cha Gliosarcoma pomwe chiwopsezo chokhudzana ndi majini ndi BRAF. Izi ndichifukwa choti Nance amawonjezera njira za biochemical zomwe zimatsutsana ndi oyendetsa siginecha ake.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu zipatso za Acerola ndi Apigenin, Curcumin, Quercetin, Lupeol, Formononetin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Oncogenic Cancer Epigenetics ndi Stem Cell Signaling ndi ena. Acerola sivomerezedwa ngati chiwopsezo cha Gliosarcoma chikugwirizana ndi chiwopsezo cha majini ndi BRAF chifukwa chimawonjezera ma signature awo.

FRUIT NANCE AKUKONZEDWA PA ACEROLA PA BRAF GENETIC RISK OF CANCER.

Sankhani Nut COMMON WALNUT kapena EUROPEAN CHESTNUT?

Walnut wamba amakhala ndi zinthu zambiri zogwira ntchito kapena bioactives monga Curcumin, Quercetin, Ellagic Acid, Lupeol, Formononetin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Kuzindikiritsa kwa MAPK, Kukonzanso kwa DNA, Ma cell Cycle Checkpoints ndi MYC Signaling ndi ena. Walnut wamba amalangizidwa pachiwopsezo cha Gliosarcoma pomwe chiwopsezo cha majini ndi BRAF. Izi ndichifukwa choti Common Walnut imachulukitsa njira za biochemical zomwe zimatsutsana ndi oyendetsa siginecha ake.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu European Chestnut ndi Apigenin, Curcumin, Quercetin, Ellagic Acid, Lupeol. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Stem Cell Signaling ndi ena. European Chestnut sivomerezedwa ngati chiopsezo cha Gliosarcoma ngati chiwopsezo cha majini ndi BRAF chifukwa chimawonjezera njira zake.

WALNUT WAMWAMBA AMAKONZEDWA PA CHESTNUT YA KU ULAYA PA BRAF GENETIC RISK OF CANCER.

Pomaliza

Zakudya ndi Zowonjezera zomwe zasankhidwa ndizofunikira kwambiri pamakhansa ngati Gliosarcoma. Odwala a Gliosarcoma ndi anthu omwe ali pachiwopsezo cha majini nthawi zonse amakhala ndi funso ili: "Ndi zakudya ziti ndi zakudya zowonjezera zomwe zimandilimbikitsa komanso zomwe sizili?" Pali chikhulupiliro chofala chomwe ndi lingaliro lolakwika kuti zakudya zonse zokhala ndi mbewu zitha kukhala zopindulitsa kapena ayi koma sizingakhale zovulaza. Zakudya zina ndi zowonjezera zimatha kusokoneza chithandizo cha khansa kapena kulimbikitsa madalaivala a khansa.

Pali mitundu yosiyanasiyana yazizindikiro za khansa monga Gliosarcoma, iliyonse ili ndi chibadwa chosiyana cha chotupa chokhala ndi ma genomic osiyanasiyana pamunthu aliyense. Kuphatikiza apo, chithandizo chilichonse cha khansa ndi chemotherapy chili ndi njira yapadera yochitira. Chakudya chilichonse monga Kolifulawa chimakhala ndi ma bioactive osiyanasiyana mosiyanasiyana, omwe amakhudza njira zosiyanasiyana zama biochemical. Tanthauzo la zakudya zamunthu payekhapayekha ndi malingaliro amunthu payekhapayekha pazowonetsa khansa, machiritso, ma genetic, moyo ndi zina. Zosankha zokhudzana ndi thanzi la khansa zimafuna kudziwa za biology ya khansa, sayansi yazakudya komanso kumvetsetsa kwamankhwala osiyanasiyana a chemotherapy. Pomaliza pakakhala kusintha kwamankhwala kapena ma genomics atsopano azindikirika - kusintha kwa zakudya kumafunika kuunikanso.

Njira yothetsera makonda a addon imapangitsa kupanga chisankho kukhala kosavuta ndikuchotsa malingaliro onse poyankha funso, "Ndi zakudya ziti zomwe ndiyenera kusankha kapena kusasankha Gliosarcoma?". Gulu la addon lamitundu yambiri limaphatikizapo madokotala a khansa, asayansi azachipatala, akatswiri opanga mapulogalamu ndi asayansi a data.

Zothandizira

• Glioma Mskcc 2019
• Tumor mutational load imalosera kupulumuka pambuyo pa immunotherapy pamitundu ingapo ya khansa.
• Kupewa kwa butyric acid, nicotinamide, calcium glucarate yokha kapena kuphatikiza pa 7, 12-dimethylbenz (a) anthracene induced mouse skin tumorigenesis kudzera modulation of K-Ras-PI3K-AKTpathway and related micro RNAs.
• Naringin imalimbikitsa ma cell a khansa ya prostate ku chithandizo cha paclitaxel.
• Brassinin Yophatikizidwa ndi Capsaicin Imawonjezera Apoptotic ndi Anti-metastatic Effects mu PC-3 Human Prostate Cancer Cells.
• Kuwongolera koyipa kwa transducer ya ma signal ndi activator ya transcript-3 signing cascade ndi lupeol imalepheretsa kukula ndikupangitsa apoptosis mu cell hepatocellular carcinoma.