Zakudya Zam'mimba Stromal Sarcoma!

Introduction

Zakudya za Stromal Sarcoma za m'mimba ziyenera kukhala zamunthu aliyense payekha komanso ziyenera kusinthidwa ndi chithandizo cha khansa kapena kusintha kwa chibadwa cha chotupa. Kusintha kwamunthu ndikusintha kuyenera kuganizira zonse zomwe zimagwira ntchito kapena ma bioactive omwe ali muzakudya zosiyanasiyana molingana ndi biology ya khansa, majini, chithandizo, moyo komanso zomwe amakonda. Chifukwa chake ngakhale zakudya ndi chimodzi mwazosankha zofunika kwambiri kwa wodwala khansa komanso munthu yemwe ali pachiwopsezo cha khansa - momwe angasankhire zakudya zomwe angadye si ntchito yophweka.

Kwa Gastrointestinal Stromal Sarcoma kodi zili ndi masamba, zipatso, mtedza, mbewu zomwe munthu amadya?

Funso lodziwika bwino lazakudya lomwe limafunsidwa ndi odwala khansa komanso anthu omwe ali pachiwopsezo cha khansa ndi - la khansa ngati Gastrointestinal Stromal Sarcoma kodi zilibe kanthu kuti ndi zakudya ziti zomwe ndimadya komanso zomwe sindidya? Kapena ngati nditsatira zakudya zochokera ku zomera ndizokwanira khansa ngati Gastrointestinal Stromal Sarcoma?

Mwachitsanzo, kodi zilibe kanthu ngati masamba a Bitter Gourd amadyedwa kwambiri poyerekeza ndi Kohlrabi? Kodi pamakhala kusiyana kulikonse ngati Pummelo amakondedwa kuposa makangaza? Komanso ngati kusankha kofanana kumapangidwira mtedza/mbewu monga Butternut pamwamba pa Chestnut ndi ma pulse ngati Adzuki Bean pa Lima Bean. Ndipo ngati zomwe ndimadya zili ndi vuto - ndiye kuti munthu angadziwe bwanji zakudya zomwe zimalimbikitsidwa ndi Gastrointestinal Stromal Sarcoma ndipo ndi yankho lomwelo kwa aliyense yemwe ali ndi matenda omwewo kapena chiwopsezo cha chibadwa?

Inde! Zakudya zomwe mumadya ndizofunikira pa Gastrointestinal Stromal Sarcoma!

Malingaliro a zakudya sangakhale ofanana kwa aliyense ndipo akhoza kukhala osiyana ngakhale pa matenda omwewo komanso chiopsezo cha majini.

Zakudya zonse (masamba, zipatso, mtedza, mbewu, phala, mafuta ndi zina) ndi zakudya zopatsa thanzi zimapangidwa ndi mamolekyulu opitilira imodzi kapena zogwira ntchito mosiyanasiyana komanso kuchuluka kwake. Chilichonse chogwiritsidwa ntchito chimakhala ndi njira yapadera yochitirapo kanthu - yomwe imatha kuyambitsa kapena kuletsa njira zosiyanasiyana zama biochemical. Zakudya zongotchulidwa mwachidule ndi zowonjezera zomwe zimalimbikitsidwa ndizomwe sizimayambitsa kuchuluka kwa maselo oyambitsa khansa koma zimawachepetsa. Apo ayi zakudya zimenezo siziyenera kuvomerezedwa. Zakudya zimakhala ndi zosakaniza zingapo zomwe zimagwira ntchito - chifukwa chake powunika zakudya ndi zowonjezera, muyenera kuganizira momwe zosakaniza zonse zimakhudzira thupi limodzi osati payekhapayekha.

Mwachitsanzo, Pummelo ili ndi zinthu zomwe zimagwira ntchito monga Quercetin, Curcumin, Formononetin, Lupeol, Daidzein. Ndipo makangaza ali ndi zinthu zogwira ntchito Ellagic Acid, Quercetin, Curcumin, Formononetin, Lupeol ndi mwina ena.

Kulakwitsa kofala komwe kumachitika posankha ndikusankha zakudya zodyera za Gastrointestinal Stromal Sarcoma - ndikuwunika zosankhidwa zokha zomwe zili muzakudya ndikunyalanyaza zina zonse. Chifukwa zosakaniza zosiyanasiyana zomwe zili muzakudya zitha kukhala ndi zotsatira zotsutsana ndi oyendetsa khansa - simungasankhe zosakaniza muzakudya ndi zowonjezera kuti mupange chisankho chazakudya cha Gastrointestinal Stromal Sarcoma.

INDE - ZOSANKHA CHAKUDYA NDINKHANI PA KANSA. ZINSINSI ZA KALERE ZIYENERA KUGANIZIRA ZONSE ZONSE ZOKHUDZA ZOKHUDZA ZAKUDYA.

Maluso Ofunika Pakupanga Chakudya Mwamakonda pa Gastrointestinal Stromal Sarcoma?

Zakudya zamakhansa monga Gastrointestinal Stromal Sarcoma zimakhala ndi zakudya zovomerezeka / zowonjezera; zakudya zosavomerezeka / zowonjezera zomwe zili ndi maphikidwe achitsanzo omwe amaika patsogolo kugwiritsa ntchito zakudya zoyenera. Chitsanzo cha kadyedwe kake kamakonda kuwoneka pa izi kugwirizana.

Kusankha zakudya zomwe zimalangizidwa kapena ayi ndizovuta kwambiri, zomwe zimafuna ukadaulo wa Gastrointestinal Stromal Sarcoma biology, sayansi yazakudya, majini, biochemistry komanso kumvetsetsa bwino momwe chithandizo cha khansa chimagwirira ntchito komanso zovuta zina zomwe chithandizocho chingasiye kugwira ntchito.

ZOCHEPA ZODZIWA ZOCHEPA ZOFUNIKA KUTI MUZITHANDIZA KUKHALA KWA MANKHWALA A KANSA NDI: CANCER BIOLOGY, FOOD SAYANSI, MANKHWALA A KANSA NDI MA GENETICS.

Makhalidwe a khansa monga Gastrointestinal Stromal Sarcoma

Makhansa onse monga Gastrointestinal Stromal Sarcoma amatha kudziwika ndi njira zapadera za biochemical - njira zosayina za Gastrointestinal Stromal Sarcoma. Njira zama biochemical monga Cell Cycle, MAPK Signaling, PI3K-AKT-MTOR Signaling, Growth Factor Signaling ndi gawo la tanthauzo la Gastrointestinal Stromal Sarcoma. Mitundu ya khansa ya munthu aliyense imatha kukhala yosiyana chifukwa chake siginecha yawo yeniyeni ya khansa imatha kukhala yapadera.

Chithandizo chomwe chili chothandiza pa Gastrointestinal Stromal Sarcoma chikuyenera kuzindikirika ndi siginecha ya biochemical njira za wodwala khansa aliyense komanso munthu yemwe ali pachiwopsezo cha majini. Choncho mankhwala osiyanasiyana omwe ali ndi njira zosiyanasiyana zochitira zinthu ndi othandiza kwa odwala osiyanasiyana. Momwemonso komanso pazifukwa zomwezo zakudya ndi zowonjezera ziyenera kukhala zamunthu aliyense payekhapayekha. Chifukwa chake zakudya zina ndi zowonjezera zimalimbikitsidwa kwa Gastrointestinal Stromal Sarcoma mukamamwa mankhwala a khansa Octreotide, ndipo zakudya zina ndi zowonjezera sizimalimbikitsidwa.

Magwero ngati cBioPortal ndipo ena ambiri amapereka deta yosadziwika ya odwala omwe ali ndi chiwerengero cha anthu omwe amachokera ku mayesero a zachipatala pa zizindikiro zonse za khansa. Izi zili ndi tsatanetsatane wa kafukufuku wazachipatala monga kukula kwa zitsanzo / kuchuluka kwa odwala, magulu azaka, jenda, fuko, chithandizo, malo otupa ndi masinthidwe aliwonse.

KIT, TSC1, SETD2, MAX ndi PDGFRA ndi omwe ali pamwamba pa jini za Gastrointestinal Stromal Sarcoma. KIT imanenedwa mu 5.2 % ya odwala oyimira m'mayesero onse azachipatala. Ndipo TSC1 imanenedwa mu 1.1%. Deta yophatikizidwa ya odwala imaphimba zaka kuyambira 16 mpaka 90. 55.2 % ya data ya odwala amadziwika kuti ndi amuna. The Gastrointestinal Stromal Sarcoma biology pamodzi ndi ma genetics omwe adanenedwa palimodzi amafotokozera kuchuluka kwazomwe zimayimiridwa ndi njira zama biochemical za khansa iyi. Ngati chibadwa cha khansa ya munthu kapena majini omwe amathandizira pachiwopsezo amadziwikanso ndiye kuti ayenera kugwiritsidwanso ntchito pakusintha zakudya.

ZOSANKHA ZA KALERE ZIYENERA KUGWIRITSA NTCHITO NDI SIZINI YA KANSA YA MUNTHU ALIYENSE.

Chakudya ndi Zowonjezera za Gastrointestinal Stromal Sarcoma

Kwa Odwala Khansa

Odwala khansa omwe ali ndi chithandizo chamankhwala kapena ochepetsa chithandizo chamankhwala amayenera kupanga zisankho pazakudya ndi zowonjezera - pazakudya zopatsa thanzi, kuthana ndi zovuta zilizonse komanso kuwongolera kasamalidwe ka khansa. Zakudya zonse zozikidwa pamasamba sizofanana ndipo kusankha ndikuyika patsogolo zakudya zomwe zimasankhidwa payekhapayekha komanso zomwe zimasinthidwa kuti zigwiritsidwe ntchito ndi khansa ndizofunikira komanso zovuta. Nazi zitsanzo zopereka malangizo opangira zisankho za kadyedwe.

Sankhani Vegetable BITTER GOURD kapena KOHLRABI?

Gourd Wowawa Wamasamba ali ndi zinthu zambiri zogwira ntchito kapena bioactives monga Curcumin, Formononetin, Lupeol, Daidzein, Isoliquiritigenin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga MAPK Signaling, JAK-STAT Signaling, Angiogenesis ndi PI3K-AKT-MTOR Signaling ndi ena. Bitter Gourd akulimbikitsidwa kuti agwiritse ntchito Gastrointestinal Stromal Sarcoma pamene chithandizo cha khansa chopitirira ndi Octreotide. Izi zili choncho chifukwa Bitter Gourd imasintha njira za biochemical zomwe zanenedwa mwasayansi kuti zidziwitse mphamvu ya Octreotide.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu masamba a Kohlrabi ndi Quercetin, Curcumin, Formononetin, Lupeol, Daidzein. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga MAPK Signaling, WNT Beta Catenin Signaling ndi PI3K-AKT-MTOR Signaling ndi ena. Kohlrabi siyovomerezeka kwa Gastrointestinal Stromal Sarcoma pamene chithandizo cha khansa chikupitilira ndi Octreotide chifukwa chimasintha njira zama biochemical zomwe zimapangitsa kuti chithandizo cha khansa zisamve kapena kuyankha.

MBOLE WA MASOMBE WOWAWA AMAKONZEDWA PA KOHLRABI KWA M'mimba Stromal Sarcoma NDI MACHIRETO Octreotide.

Sankhani Chipatso POMEGRANATE kapena PUMMELO?

Chipatso Makangaza ali ndi zinthu zambiri zogwira ntchito kapena bioactives monga Ellagic Acid, Quercetin, Curcumin, Formononetin, Lupeol. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga MAPK Signaling, Angiogenesis, Growth Factor Signaling ndi PI3K-AKT-MTOR Signaling ndi ena. Makangaza amalimbikitsidwa kwa Gastrointestinal Stromal Sarcoma pamene chithandizo cha khansa chopitilira ndi Octreotide. Izi zili choncho chifukwa makangaza amasintha njira za biochemical zomwe zanenedwa mwasayansi kuti zidziwitse mphamvu ya Octreotide.

Zina mwazinthu zomwe zimagwira ntchito kapena ma bioactive mu zipatso za Pummelo ndi Quercetin, Curcumin, Formononetin, Lupeol, Daidzein. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga WNT Beta Catenin Signaling ndi PI3K-AKT-MTOR Signaling ndi ena. Pummelo siyovomerezeka pa Gastrointestinal Stromal Sarcoma pamene chithandizo cha khansa chikupitirirabe ndi Octreotide chifukwa chimasintha njira zama biochemical zomwe zimapangitsa kuti chithandizo cha khansa zisamve kapena kuyankha.

ZIPATSO ZA KANGAZA AMAKONZEDWA KUPOSA PUMMELO KWA M'mimba Stromal Sarcoma NDI MANKHWALA A Octreotide.

Sankhani Nut BUTTERNUT kapena CHESTNUT?

Butternut imakhala ndi zinthu zambiri zogwira ntchito kapena bioactives monga Curcumin, Formononetin, Lupeol, Daidzein, Isoliquiritigenin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga MAPK Signaling, JAK-STAT Signaling, Angiogenesis ndi PI3K-AKT-MTOR Signaling ndi ena. Butternut amalangizidwa kuti agwiritsidwe ntchito ndi Gastrointestinal Stromal Sarcoma pamene chithandizo cha khansa chopitirira ndi Octreotide. Izi ndichifukwa choti Butternut imasintha njira zama biochemical zomwe zanenedwa mwasayansi kuti zidziwitse mphamvu ya Octreotide.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu Chestnut ndi Ellagic Acid, Curcumin, Formononetin, Lupeol, Daidzein. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga WNT Beta Catenin Signaling ndi PI3K-AKT-MTOR Signaling ndi ena. Chestnut ndi yosavomerezeka pa Gastrointestinal Stromal Sarcoma pamene chithandizo cha khansa chikupitirira ndi Octreotide chifukwa chimasintha njira za biochemical zomwe zimapangitsa kuti chithandizo cha khansa zisawonongeke kapena kuti chisamayankhe.

BUTTERNUT AMADALITSIDWA PA CHESTNUT KWA Gastrointestinal Stromal Sarcoma NDI MALANGIZO Octreotide.

Kwa Anthu Amene Ali ndi Genetic Risk of Cancer

Funso lofunsidwa ndi anthu omwe ali ndi chiopsezo cha chibadwa cha Gastrointestinal Stromal Sarcoma kapena mbiri ya banja ndi "Kodi Ndiyenera Kudya Chiyani Mosiyana ndi Kale?" ndi momwe angasankhire zakudya ndi zowonjezera kuti athe kuthana ndi kuopsa kwa matendawa. Popeza pachiwopsezo cha khansa palibe chomwe chingachitike pankhani ya chithandizo - zosankha zazakudya ndi zowonjezera zimakhala zofunika komanso chimodzi mwazinthu zochepa zomwe zingatheke. Zakudya zonse zochokera ku zomera sizofanana ndipo zimatengera chibadwa chodziwika ndi siginecha ya njira - zosankha za zakudya ndi zowonjezera ziyenera kukhala zaumwini.

Sankhani masamba a CAULIFLOWER kapena RED BELL PEPPER?

Kolifulawa wamasamba ali ndi zinthu zambiri zogwira ntchito kapena bioactives monga Curcumin, Lupeol, Isoliquiritigenin, Daidzein, Phloretin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga MAPK Signaling, RAS-RAF Signaling, Angiogenesis ndi PI3K-AKT-MTOR Signaling ndi ena. Kolifulawa akulimbikitsidwa pa chiopsezo cha Gastrointestinal Stromal Sarcoma pamene chiopsezo chokhudzana ndi majini ndi KIT. Izi ndichifukwa choti Kolifulawa imawonjezera njira zama biochemical zomwe zimatsutsana ndi madalaivala ake.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu masamba a Red Bell Tsabola ndi Quercetin, Curcumin, Lupeol, Luteolin, Isoliquiritigenin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga MAPK Signaling ndi Stem Cell Signaling ndi ena. Red Bell Pepper sivomerezedwa ngati chiopsezo cha Gastrointestinal Stromal Sarcoma pamene chiwopsezo cha chibadwa ndi KIT chifukwa chimawonjezera ma signature njira zake.

KAULIFWA WA MASABATA AMAKONZEDWA PA RED PPERPER WOFIIRA PA KIT GENETIC RISK OF CANCER.

Sankhani Zipatso BILBERRY kapena SWEET ORANGE?

Zipatso za Bilberry zili ndi zinthu zambiri zogwira ntchito kapena bioactives monga Apigenin, Quercetin, Curcumin, Lupeol, Luteolin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Kuzindikiritsa kwa MAPK, Kuwonetsa kwa MYC, Kuwonetsa Ma cell Stem ndi PI3K-AKT-MTOR Signaling ndi ena. Bilberry amalangizidwa pachiwopsezo cha Gastrointestinal Stromal Sarcoma pomwe chiopsezo chogwirizana ndi chibadwa ndi KIT. Izi ndichifukwa choti Bilberry imachulukitsa njira za biochemical zomwe zimatsutsana ndi oyendetsa siginecha ake.

Zina mwazinthu zomwe zimagwira ntchito kapena ma bioactive mu chipatso Chokoma Orange ndi D-limonene, Curcumin, Lupeol, Vitamini D3, Luteolin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Cell Cycle, Stem Cell Signaling ndi PI3K-AKT-MTOR Signaling ndi ena. Sweet Orange ali osavomerezeka pamene chiopsezo cha m'mimba Stromal Sarcoma pamene kugwirizana chibadwa chiopsezo KIT chifukwa kumawonjezera siginecha njira zake.

FRUIT BILBERRY NDIBWINO KUPANDA WOtsekemera lalanje PA KIT GENETIC RISK OF CANCER.

Sankhani Nut COMMON HAZELNUT kapena EUROPEAN CHESTNUT?

Mtedza wamba uli ndi zinthu zambiri zogwira ntchito kapena bioactives monga Quercetin, Curcumin, Lupeol, Isoliquiritigenin, Daidzein. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Kuzindikiritsa kwa MAPK, Kuwonetsa kwa MYC, Kuwonetsa Ma cell Stem ndi PI3K-AKT-MTOR Signaling ndi ena. Common Hazelnut akulimbikitsidwa kuti pakhale chiopsezo cha Gastrointestinal Stromal Sarcoma pamene chiopsezo chokhudzana ndi majini ndi KIT. Izi ndichifukwa choti Common Hazelnut imachulukitsa njira zama biochemical zomwe zimatsutsana ndi madalaivala ake.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu European Chestnut ndi Apigenin, Quercetin, Curcumin, Ellagic Acid, Lupeol. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Stem Cell Signaling ndi ena. European Chestnut sivomerezedwa ngati chiwopsezo cha Gastrointestinal Stromal Sarcoma chikugwirizana ndi chiwopsezo cha chibadwa ndi KIT chifukwa chimawonjezera ma signature awo.

HAZELNUT WAMWAMBA IMADALITSIDWA PA CHESTNUT YA KU ULAYA PA CHIFUKWA CHA GENETIC RISK OF CANCER.

Pomaliza

Zakudya ndi Zowonjezera zomwe zasankhidwa ndi zosankha zofunika pa khansa monga Gastrointestinal Stromal Sarcoma. Odwala a Stromal Sarcoma ndi anthu omwe ali pachiwopsezo cha majini nthawi zonse amakhala ndi funso ili: "Ndi zakudya ziti ndi zakudya zowonjezera zomwe zimandilimbikitsa komanso zomwe sizili?" Pali chikhulupiliro chofala chomwe ndi lingaliro lolakwika kuti zakudya zonse zokhala ndi mbewu zitha kukhala zopindulitsa kapena ayi koma sizingakhale zovulaza. Zakudya zina ndi zowonjezera zimatha kusokoneza chithandizo cha khansa kapena kulimbikitsa madalaivala a khansa.

Pali mitundu yosiyanasiyana yazizindikiro za khansa monga Gastrointestinal Stromal Sarcoma, iliyonse ili ndi chibadwa chosiyana cha chotupa chokhala ndi ma genomic osiyanasiyana pamunthu aliyense. Kuphatikiza apo, chithandizo chilichonse cha khansa ndi chemotherapy chili ndi njira yapadera yochitira. Chakudya chilichonse monga Bitter Gourd chimakhala ndi ma bioactive osiyanasiyana mosiyanasiyana, omwe amakhudza njira zosiyanasiyana zama biochemical. Tanthauzo la zakudya zamunthu payekhapayekha ndi malingaliro amunthu payekhapayekha pazowonetsa khansa, machiritso, ma genetic, moyo ndi zina. Zosankha zokhudzana ndi thanzi la khansa zimafuna kudziwa za biology ya khansa, sayansi yazakudya komanso kumvetsetsa kwamankhwala osiyanasiyana a chemotherapy. Pomaliza pakakhala kusintha kwamankhwala kapena ma genomics atsopano azindikirika - kusintha kwa zakudya kumafunika kuunikanso.

Njira yothetsera makonda a addon imapangitsa kupanga chisankho kukhala kosavuta ndikuchotsa zongopeka poyankha funso, "Ndi zakudya ziti zomwe ndiyenera kusankha kapena kusasankha pa Gastrointestinal Stromal Sarcoma?". Gulu la addon lamitundu yambiri limaphatikizapo madokotala a khansa, asayansi azachipatala, akatswiri opanga mapulogalamu ndi asayansi a data.

Zothandizira

• Msk Impact 2017
• Chithandizo cha khansa chimapanga mawonekedwe olimba a clonal hematopoiesis.
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• Betulinic acid imalepheretsa kukula kwa khansa ya prostate chifukwa cha kuletsa kwazinthu zolembera mapuloteni.
• Gallic acid, phenolic compound, imakhala ndi zotsatira zotsutsa-angiogenic kudzera mu njira yowonetsera PTEN/AKT/HIF-1α/VEGF m'maselo a khansa ya ovari.
• Kulimbikitsa kukula kwa maselo amtundu wa pulmonary adenocarcinoma ndi maselo ang'onoang'ono a epithelial airway ndi beta-carotene kudzera mu activation ya cAMP, PKA, CREB ndi ERK1/2.
• Zotsatira ndi kufunikira kwa formononetin pamawu a HIF-1α ndi VEGF mu minofu ya khansa ya khomo lachiberekero.
• Kuwongolera koyipa kwa transducer ya ma signal ndi activator ya transcript-3 signing cascade ndi lupeol imalepheretsa kukula ndikupangitsa apoptosis mu cell hepatocellular carcinoma.
• Chlorogenic acid imalepheretsa kuchulukana ndipo imapangitsa apoptosis m'maselo a khansa ya impso ya anthu A498 kudzera mu inactivating PI3K/Akt/mTOR njira yolumikizira.
• Brassinin imaletsa njira yolumikizira ya STAT3 kudzera mukusintha kwa PIAS-3 ndi SOCS-3 mawu ndikudziwitsa khansa ya m'mapapo ya anthu mu mbewa zamaliseche kupita paclitaxel.
• Kuyambitsa kwa transient receptor kuthekera mtundu wa vanilloid 1 (TRPV1) ndi capsaicin kumapangitsa Fas/CD95-mediated apoptosis ya maselo a khansa ya urothelial motengera ATM.