Zakudya za Matenda a Extramammary Paget!

Introduction

Zakudya za Extramammary Paget Disease ziyenera kukhala zamunthu aliyense payekha komanso zimayenera kusintha ngati chithandizo cha khansa kapena chotupa chikusintha. Kusintha kwamunthu ndikusintha kuyenera kuganizira zonse zomwe zimagwira ntchito kapena ma bioactive omwe ali muzakudya zosiyanasiyana molingana ndi biology ya khansa, chibadwa, chithandizo, moyo ndi zomwe amakonda. Chifukwa chake ngakhale zakudya ndi chimodzi mwazosankha zofunika kwambiri kwa wodwala khansa komanso munthu yemwe ali pachiwopsezo cha khansa - momwe angasankhire zakudya zomwe angadye si ntchito yophweka.

Matenda a Extramammary Paget's, khansa yapakhungu yosowa kwambiri yomwe imakhudza kwambiri madera omwe ali ndi tiziwalo tambiri ta apocrine, imakhala ndi zovuta zapadera pakuzindikira komanso kuchiza. Matendawa amatha kuchitika mwa amuna ndi akazi, zomwe zimachitika kwambiri mu maliseche kwa amayi komanso maliseche kapena perianal mwa amuna. Mafotokozedwe a matenda a extramammary Paget's matenda amapereka chidziwitso chofunikira pamawonekedwe ake am'manja ndikuthandizira kuwongolera chisankho chamankhwala. Chithandizo chimaphatikizapo kudulidwa opaleshoni, ndipo nthawi zina, chithandizo chamankhwala kapena ma radiotherapy amatha kuganiziridwa. Khodi ya ICD-10 ya matenda a extramammary Paget imathandizira malipoti okhazikika komanso kutsatira chithandizo. DermNet ndi zinthu zina zapakhungu zimapereka chidziwitso chofunikira pazachipatala komanso kasamalidwe ka matendawa. Ngakhale kuti matenda a extramammary Paget amakhudza kwambiri khungu, kufotokozera kwake komanso funso loti ndi lakupha kumadalira zinthu zingapo, kuphatikizapo kukhalapo kwa matenda osokoneza bongo kapena zilonda zam'mimba. Kusoweka kwa matenda a Paget's extramammary kumawonjezera zovuta pakuwerenga ndikumvetsetsa, ndikupangitsa kuti ikhale phunziro lopitilira kafukufuku. Mwachidule, kasamalidwe koyenera ka matenda a extramammary Paget kumafuna kumvetsetsa bwino za matenda ake, kuganizira mozama za njira zochiritsira, komanso kuzindikira kuopsa kwake, makamaka pazochitika zapamwamba kapena zowonongeka.

Kwa Matenda a Extramammary Paget kodi zili ndi masamba, zipatso, mtedza, mbewu zomwe munthu amadya?

Funso lodziwika bwino lazakudya lomwe limafunsidwa ndi odwala khansa komanso anthu omwe ali pachiwopsezo cha khansa ndi - la khansa ngati Extramammary Paget Disease kodi zilibe kanthu kuti ndikudya chiyani komanso zomwe sindidya? Kapena ngati nditsatira zakudya zochokera ku zomera ndizokwanira khansa monga Matenda a Extramammary Paget?

Mwachitsanzo kodi zilibe kanthu ngati masamba a Karoti amadyedwa kwambiri poyerekeza ndi Sipinachi ya Malabar? Kodi zimapanga kusiyana kulikonse ngati zipatso za Black Elderberry zimakonda kuposa Evergreen Blackberry? Komanso ngati kusankha kofanana kumapangidwira mtedza/mbewu monga Walnut waku Japan ku Europe Chestnut komanso zokometsera ngati Nsonga wamaso akuda pa Nyemba wamba. Ndipo ngati zomwe ndimadya zili ndi vuto - ndiye kuti munthu angadziwe bwanji zakudya zomwe zimalimbikitsidwa ku Matenda a Extramammary Paget ndipo ndi yankho lomwelo kwa aliyense yemwe ali ndi matenda omwewo kapena chiwopsezo cha majini?

Inde! Zakudya zomwe mumadya ndizofunikira pa Matenda a Extramammary Paget!

Malingaliro a zakudya sangakhale ofanana kwa aliyense ndipo akhoza kukhala osiyana ngakhale pa matenda omwewo komanso chiopsezo cha majini.

Zakudya zonse (masamba, zipatso, mtedza, mbewu, phala, mafuta ndi zina) ndi zakudya zopatsa thanzi zimapangidwa ndi mamolekyulu opitilira imodzi kapena zogwira ntchito mosiyanasiyana komanso kuchuluka kwake. Chilichonse chogwiritsidwa ntchito chimakhala ndi njira yapadera yochitirapo kanthu - yomwe imatha kuyambitsa kapena kuletsa njira zosiyanasiyana zama biochemical. Zakudya zongotchulidwa mwachidule ndi zowonjezera zomwe zimalimbikitsidwa ndizomwe sizimayambitsa kuchuluka kwa maselo oyambitsa khansa koma zimawachepetsa. Apo ayi zakudya zimenezo siziyenera kuvomerezedwa. Zakudya zimakhala ndi zosakaniza zingapo zomwe zimagwira ntchito - chifukwa chake powunika zakudya ndi zowonjezera, muyenera kuganizira momwe zosakaniza zonse zimakhudzira thupi limodzi osati payekhapayekha.

Mwachitsanzo Black Elderberry ili ndi zinthu zogwira ntchito Curcumin, Daidzein, Formononetin, Cinnamaldehyde, Melatonin. Ndipo Evergreen Blackberry ili ndi zopangira Ellagic Acid, Cinnamaldehyde, Eugenol, Myricetin, Linalool ndi ena.

Kulakwitsa kofala komwe kumachitika posankha ndikusankha zakudya zodyera Extramammary Paget Disease - ndikuwunika zosankhidwa zokha zomwe zili muzakudya ndikunyalanyaza zina zonse. Chifukwa zosakaniza zosiyanasiyana zomwe zili muzakudya zitha kukhala ndi zotsatira zotsutsana ndi oyendetsa khansa - simungathe kusankha zosakaniza muzakudya ndi zowonjezera kuti mupange chisankho chazakudya cha Extramammary Paget Disease.

INDE - ZOSANKHA CHAKUDYA NDINKHANI PA KANSA. ZINSINSI ZA KALERE ZIYENERA KUGANIZIRA ZONSE ZONSE ZOKHUDZA ZOKHUDZA ZAKUDYA.

Maluso Ofunika Pakukonda Chakudya Chake pa Matenda a Extramammary Paget?

Zakudya zamakhansa monga Extramammary Paget Disease zimakhala ndi zakudya zovomerezeka / zowonjezera; zakudya zosavomerezeka / zowonjezera zomwe zili ndi maphikidwe achitsanzo omwe amaika patsogolo kugwiritsa ntchito zakudya zoyenera. Chitsanzo cha kadyedwe kake kamakonda kuwoneka pa izi kugwirizana.

Kusankha zakudya zomwe zimalangizidwa kapena ayi ndizovuta kwambiri, zomwe zimafuna ukatswiri mu biology ya Matenda a Extramammary Paget, sayansi yazakudya, majini, biochemistry komanso kumvetsetsa bwino momwe chithandizo cha khansa chimagwirira ntchito komanso zovuta zomwe mankhwalawo angasiye kugwira ntchito.

ZOCHEPA ZODZIWA ZOCHEPA ZOFUNIKA KUTI MUZITHANDIZA KUKHALA KWA MANKHWALA A KANSA NDI: CANCER BIOLOGY, FOOD SAYANSI, MANKHWALA A KANSA NDI MA GENETICS.

Makhalidwe a khansa ngati Matenda a Extramammary Paget

Makhansa onse monga Matenda a Extramammary Paget amatha kudziwika ndi njira yapadera ya biochemical - njira zosainira za Matenda a Extramammary Paget. Njira zama biochemical monga PI3K-AKT-MTOR Signaling, Growth Factor Signaling, Chromatin Remodeling, MAPK Signaling ndi gawo la tanthauzo la siginecha ya Extramammary Paget Disease. Mitundu ya khansa ya munthu aliyense imatha kukhala yosiyana chifukwa chake siginecha yawo yeniyeni ya khansa imatha kukhala yapadera.

Chithandizo chomwe chili chothandiza pa Matenda a Extramammary Paget akuyenera kuzindikirika ndi ma signature a biochemical omwe amagwirizana nawo kwa wodwala khansa aliyense komanso munthu yemwe ali pachiwopsezo cha majini. Choncho mankhwala osiyanasiyana omwe ali ndi njira zosiyanasiyana zochitira zinthu ndi othandiza kwa odwala osiyanasiyana. Momwemonso komanso pazifukwa zomwezo zakudya ndi zowonjezera ziyenera kukhala zamunthu aliyense payekhapayekha. Chifukwa chake zakudya zina ndi zowonjezera zimalimbikitsidwa kwa Matenda a Extramammary Paget mukamamwa mankhwala a khansa Pazopanib, ndipo zakudya zina ndi zowonjezera sizimalimbikitsidwa.

Magwero ngati cBioPortal ndipo ena ambiri amapereka deta yosadziwika ya odwala omwe ali ndi chiwerengero cha anthu omwe amachokera ku mayesero a zachipatala pa zizindikiro zonse za khansa. Izi zili ndi tsatanetsatane wa kafukufuku wazachipatala monga kukula kwa zitsanzo / kuchuluka kwa odwala, magulu azaka, jenda, fuko, chithandizo, malo otupa ndi masinthidwe aliwonse.

ERBB2, PPP2R1A ndi SMARCA4 ndi omwe ali pamwamba pa jini ya Extramammary Paget Disease. ERBB2 imanenedwa mu 33.3% ya odwala oyimira m'mayesero onse azachipatala. Ndipo PPP2R1A imanenedwa mu 33.3%. Deta yophatikizidwa ya odwala imakhudza zaka kuyambira mpaka . 50.0 % ya deta ya odwala amadziwika kuti ndi amuna. The Extramammary Paget Disease biology pamodzi ndi ma genetics omwe adanenedwa palimodzi amatanthauzira kuchuluka kwa anthu omwe amayimira njira zama biochemical za khansa iyi. Ngati chibadwa cha khansa ya munthu kapena majini omwe amathandizira pachiwopsezo amadziwikanso ndiye kuti ayenera kugwiritsidwanso ntchito pakusintha zakudya.

ZOSANKHA ZA KALERE ZIYENERA KUGWIRITSA NTCHITO NDI SIZINI YA KANSA YA MUNTHU ALIYENSE.

Chakudya ndi Zowonjezera pa Matenda a Extramammary Paget

Kwa Odwala Khansa

Odwala khansa omwe ali ndi chithandizo chamankhwala kapena ochepetsa chithandizo chamankhwala amayenera kupanga zisankho pazakudya ndi zowonjezera - pazakudya zopatsa thanzi, kuthana ndi zovuta zilizonse komanso kuwongolera kasamalidwe ka khansa. Zakudya zonse zozikidwa pamasamba sizofanana ndipo kusankha ndikuyika patsogolo zakudya zomwe zimasankhidwa payekhapayekha komanso zomwe zimasinthidwa kuti zigwiritsidwe ntchito ndi khansa ndizofunikira komanso zovuta. Nazi zitsanzo zopereka malangizo opangira zisankho za kadyedwe.

Sankhani masamba a CARROT kapena MALABAR SPINACH?

Karoti wamasamba ali ndi zinthu zambiri zogwira ntchito kapena bioactives monga Curcumin, Gamma-linolenic Acid, Daidzein, Formononetin, Cinnamaldehyde. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga PI3K-AKT-MTOR Signaling ndi ena. Karoti amalangizidwa pa Matenda a Extramammary Paget pamene chithandizo cha khansa chikupitirirabe ndi Pazopanib. Izi ndichifukwa choti Karoti amasintha njira zama biochemical zomwe zanenedwa mwasayansi kuti zidziwitse zotsatira za Pazopanib.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu masamba a Malabar Sipinachi ndi Curcumin, Daidzein, Formononetin, Cinnamaldehyde, Melatonin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga PI3K-AKT-MTOR Signaling ndi ena. Sipinachi ya Malabar siyovomerezeka kwa Matenda a Extramammary Paget pamene chithandizo cha khansa chikupitirirabe ndi Pazopanib chifukwa chimasintha njira za biochemical zomwe zimapangitsa kuti chithandizo cha khansa zisawonongeke kapena kuti chisamayankhe.

KAROTI WA MASAMBA AKUKONZEDWA PA MALABAR SPINACH PA ZOKHUDZA ZA Extramammary Paget Matenda NDI Mchiritsi wa Pazopanib.

Sankhani Zipatso EVERGREEN BLACKBERRY kapena BLACK ELDERBERRY?

Chipatso Evergreen Blackberry ili ndi zinthu zambiri zomwe zimagwira ntchito kapena bioactives monga Ellagic Acid, Cinnamaldehyde, Eugenol, Myricetin, Linalool. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga PI3K-AKT-MTOR Signaling ndi ena. Evergreen Blackberry ikulimbikitsidwa ku matenda a Extramammary Paget pamene chithandizo cha khansa chikuchitika ndi Pazopanib. Izi ndichifukwa choti Evergreen Blackberry imasintha njira zama biochemical zomwe zanenedwa mwasayansi kuti zidziwitse zotsatira za Pazopanib.

Zina mwazinthu zomwe zimagwira ntchito kapena ma bioactive mu zipatso za Black Elderberry ndi Curcumin, Daidzein, Formononetin, Cinnamaldehyde, Melatonin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga PI3K-AKT-MTOR Signaling ndi ena. Black Elderberry sivomerezedwa kwa Matenda a Extramammary Paget pamene chithandizo cha khansa chikupitirirabe ndi Pazopanib chifukwa chimasintha njira za biochemical zomwe zimapangitsa kuti chithandizo cha khansa zisawonongeke kapena kuti chisamayankhe.

FRUIT EVERGREEN BLACKBERRY AKUYAMBIRA PA BLACK ELDERBERRY KWA Extramammary Paget Matenda NDI MANKHWALA Pazopanib.

Sankhani Nut JAPANESE WALNUT kapena EUROPEAN CHESTNUT?

Walnut waku Japan uli ndi zinthu zambiri zogwira ntchito kapena bioactives monga Curcumin, Ellagic Acid, Daidzein, Cinnamaldehyde, Formononetin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga PI3K-AKT-MTOR Signaling ndi ena. Walnut waku Japan amalimbikitsidwa ku Matenda a Extramammary Paget pamene chithandizo cha khansa chikupitilira ndi Pazopanib. Izi ndichifukwa choti Walnut waku Japan amasintha njira zama biochemical zomwe zanenedwa mwasayansi kuti zidziwitse zotsatira za Pazopanib.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu European Chestnut ndi Curcumin, Ellagic Acid, Daidzein, Cinnamaldehyde, Formononetin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga PI3K-AKT-MTOR Signaling ndi ena. European Chestnut ndiyosavomerezeka ku Matenda a Extramammary Paget pamene chithandizo cha khansa chikupitilira ndi Pazopanib chifukwa chimasintha njira zama biochemical zomwe zimapangitsa kuti chithandizo cha khansa chisamve kapena kuyankha.

WALNUT WA KU JAPANESE AKUKONZEDWA PA CHESTNUT YA KU ULAYA PA NKHANI YA Extramammary Paget Matenda NDI Mchiritsi wa Pazopanib.

Kwa Anthu Amene Ali ndi Genetic Risk of Cancer

Funso lofunsidwa ndi anthu omwe ali ndi chiopsezo cha chibadwa cha Matenda a Extramammary Paget kapena mbiri ya banja ndi "Kodi Ndiyenera Kudya Chiyani Mosiyana ndi Kale?" ndi momwe angasankhire zakudya ndi zowonjezera kuti athe kuthana ndi kuopsa kwa matendawa. Popeza pachiwopsezo cha khansa palibe chomwe chingachitike pankhani ya chithandizo - zosankha zazakudya ndi zowonjezera zimakhala zofunika komanso chimodzi mwazinthu zochepa zomwe zingatheke. Zakudya zonse zochokera ku zomera sizofanana ndipo zimatengera chibadwa chodziwika ndi siginecha ya njira - zosankha za zakudya ndi zowonjezera ziyenera kukhala zaumwini.

Sankhani Masamba NEW ZEALAND SPINACH kapena CUCURBITA?

Masamba a New Zealand Sipinachi ali ndi zinthu zambiri zogwira ntchito kapena bioactives monga Curcumin, Apigenin, Delphinidin, Quercetin, Lycopene. Zosakaniza zogwira izi zimagwiritsa ntchito njira zingapo zama biochemical monga Kuzindikiritsa kwa MAPK, Kuwonetsa Phospholipase, Kuwonetsa Kukula kwa Factor ndi MYC Signaling ndi ena. Sipinachi ya New Zealand imalimbikitsidwa kuti ikhale pachiwopsezo cha Matenda a Extramammary Paget pamene chiwopsezo chokhudzana ndi majini ndi ERBB2. Izi ndichifukwa choti Sipinachi ya New Zealand imachulukitsa njira za biochemical zomwe zimatsutsana ndi oyendetsa siginecha ake.

Zina mwazinthu zomwe zimagwira ntchito kapena ma bioactive mu masamba a Cucurbita ndi Curcumin, Delphinidin, Daidzein, Lupeol, Formononetin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga MYC Signaling ndi PI3K-AKT-MTOR Signaling ndi ena. Cucurbita sichivomerezedwa ngati chiopsezo cha matenda a Extramammary Paget pamene chiwopsezo cha majini ndi ERBB2 chifukwa chimawonjezera njira zake.

VEGETABLE NEW ZEALAND SPINACH AMAKONZEDWA PA CUCURBITA PA ERBB2 GENETIC RISK OF CANCER.

Sankhani Chipatso BILBERRY kapena PUMMELO?

Zipatso za Bilberry zili ndi zinthu zambiri zogwira ntchito kapena bioactives monga Curcumin, Apigenin, Delphinidin, Quercetin, Lycopene. Zosakaniza zogwira izi zimagwiritsa ntchito njira zingapo zama biochemical monga Kuzindikiritsa kwa MAPK, Ma cell Cycle Checkpoints, Phospholipase Signaling ndi MYC Signaling ndi ena. Bilberry ikulimbikitsidwa kuti pakhale chiopsezo cha Matenda a Extramammary Paget pamene chiopsezo chokhudzana ndi majini ndi ERBB2. Izi ndichifukwa choti Bilberry imachulukitsa njira za biochemical zomwe zimatsutsana ndi oyendetsa siginecha ake.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu zipatso Pummelo ndi Curcumin, Apigenin, Delphinidin, Naringenin, Hesperetin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Cell Cycle Checkpoints ndi Epithelial to Mesenchymal Transition ndi ena. Pummelo sichivomerezedwa pamene chiopsezo cha Extramammary Paget Disease pamene chiwopsezo cha majini chikugwirizana ndi ERBB2 chifukwa chimawonjezera njira zake.

FRUIT BILBERRY NDIKONDIKONZEDWA PA PUMMELO PA ERBB2 GENETIC RISK OF CANCER.

Sankhani Nut COMMON HAZELNUT kapena CHESTNUT?

Hazelnut Wamba imakhala ndi zinthu zambiri zogwira ntchito kapena bioactives monga Curcumin, Delphinidin, Quercetin, Lycopene, Daidzein. Zosakaniza zogwira izi zimagwiritsa ntchito njira zingapo zama biochemical monga Kuzindikiritsa kwa MAPK, Kuwonetsa Phospholipase, Kuwonetsa Kukula kwa Factor ndi MYC Signaling ndi ena. Common Hazelnut akulimbikitsidwa kuti pakhale chiopsezo cha Extramammary Paget Disease pamene chiopsezo chokhudzana ndi majini ndi ERBB2. Izi ndichifukwa choti Common Hazelnut imachulukitsa njira zama biochemical zomwe zimatsutsana ndi madalaivala ake.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu Chestnut ndi Curcumin, Ellagic Acid, Apigenin, Delphinidin, Lycopene. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Cell Cycle Checkpoints ndi Epithelial to Mesenchymal Transition ndi ena. Chestnut sichivomerezedwa pamene chiopsezo cha Extramammary Paget Disease pamene chiwopsezo cha chibadwa ndi ERBB2 chifukwa chimawonjezera njira zake.

HAZELNUT WAMWAMBA AMAKONZEDWA PA CHESTNUT PA ERBB2 GENETIC RISK OF CANCER.

Pomaliza

Zakudya ndi Zowonjezera zomwe zasankhidwa ndi zosankha zofunika pa khansa monga Matenda a Extramammary Paget. Odwala a Extramammary Paget Disease komanso anthu omwe ali pachiwopsezo cha majini nthawi zonse amakhala ndi funso ili: "Ndi zakudya ziti ndi zakudya zowonjezera zomwe zimandilimbikitsa komanso zomwe sizili?" Pali chikhulupiliro chofala chomwe ndi lingaliro lolakwika kuti zakudya zonse zokhala ndi mbewu zitha kukhala zopindulitsa kapena ayi koma sizingakhale zovulaza. Zakudya zina ndi zowonjezera zimatha kusokoneza chithandizo cha khansa kapena kulimbikitsa madalaivala a khansa.

Pali mitundu yosiyanasiyana yazizindikiro za khansa monga Matenda a Extramammary Paget, iliyonse ili ndi chibadwa chosiyana cha chotupa chokhala ndi ma genomic osiyanasiyana pamunthu aliyense. Kuphatikiza apo, chithandizo chilichonse cha khansa ndi chemotherapy chili ndi njira yapadera yochitira. Chakudya chilichonse monga Karoti chimakhala ndi ma bioactive osiyanasiyana mosiyanasiyana, omwe amakhudza njira zosiyanasiyana zama biochemical. Tanthauzo la zakudya zamunthu payekhapayekha ndi malingaliro amunthu payekhapayekha pazowonetsa khansa, machiritso, ma genetic, moyo ndi zina. Zosankha zokhudzana ndi thanzi la khansa zimafuna kudziwa za biology ya khansa, sayansi yazakudya komanso kumvetsetsa kwamankhwala osiyanasiyana a chemotherapy. Pomaliza pakakhala kusintha kwamankhwala kapena ma genomics atsopano azindikirika - kusintha kwa zakudya kumafunika kuunikanso.

Njira yothetsera makonda a addon imapangitsa kupanga chisankho kukhala kosavuta ndikuchotsa zongoyerekeza poyankha funso, "Ndi zakudya ziti zomwe ndiyenera kusankha kapena kusasankha pa Matenda a Extramammary Paget?". Gulu la addon lamitundu yambiri limaphatikizapo madokotala a khansa, asayansi azachipatala, akatswiri opanga mapulogalamu ndi asayansi a data.

Zothandizira

• Msk Impact 2017
• Mawonekedwe osinthika a khansa ya metastatic adawululidwa kuchokera kwa odwala 10,000 omwe akuyembekezeka.
• Daidzein imachita zotsutsana ndi zotupa motsutsana ndi ma cell a khansa ya chikhodzodzo kudzera pakuletsa njira ya FGFR3.
• Asidi ya Shikimic imalimbikitsa estrogen receptor (ER) -ma cell a khansa ya m'mawere yowonjezereka kudzera mu kutsegula kwa NF-κB chizindikiro.
• Kutulutsa kwa sinamoni yamadzimadzi (ACE-c) kuchokera ku khungwa la Cinnamomum cassia kumayambitsa apoptosis mu cell line ya khomo lachiberekero (SiHa) chifukwa cha kutayika kwa nembanemba ya mitochondrial.
• Kupewa kwa butyric acid, nicotinamide, calcium glucarate yokha kapena kuphatikiza pa 7, 12-dimethylbenz (a) anthracene induced mouse skin tumorigenesis kudzera modulation of K-Ras-PI3K-AKTpathway and related micro RNAs.
• Kafukufuku akupita patsogolo pa zotsatira za anticancer za vitamini K2.
• https://my.clevelandclinic.org/health/diseases/24266-extramammary-pagets-disease
• https://www.ncbi.nlm.nih.gov/books/NBK493224