Zakudya za Khansa ya Chithokomiro!

Introduction

Zakudya za Khansa ya Chithokomiro ziyenera kukhala zamunthu payekhapayekha komanso zimayenera kusintha ngati chithandizo cha khansa kapena chotupa chikusintha. Kusintha kwamunthu ndikusintha kuyenera kuganizira zonse zomwe zimagwira ntchito kapena ma bioactive omwe ali muzakudya zosiyanasiyana molingana ndi biology ya khansa, majini, chithandizo, moyo komanso zomwe amakonda. Chifukwa chake ngakhale zakudya ndi chimodzi mwazosankha zofunika kwambiri kwa wodwala khansa komanso munthu yemwe ali pachiwopsezo cha khansa - momwe angasankhire zakudya zomwe angadye si ntchito yophweka.

Kwa Khansa ya Chithokomiro Kodi zilibe kanthu zomwe munthu amadya zamasamba, zipatso, mtedza, mbewu?

Funso lodziwika bwino lazakudya lomwe limafunsidwa ndi odwala khansa komanso anthu omwe ali pachiwopsezo cha khansa ndi - la khansa ngati Khansa ya Chithokomiro, zilibe kanthu kuti ndi zakudya ziti zomwe ndimadya komanso zomwe sindidya? Kapena ngati nditsatira zakudya zochokera ku zomera ndizokwanira ku khansa monga Khansa ya Chithokomiro?

Mwachitsanzo, kodi zilibe kanthu ngati Kolifulawa wamasamba amadyedwa kwambiri poyerekeza ndi Kale? Kodi pamakhala kusiyana kulikonse ngati zipatso za Sea-buckthornberry zimakondedwa kuposa Black Mulberry? Komanso ngati kusankha kofananako kumapangidwa pa mtedza/mbewu monga Butternut pa Flaxseed ndi nyemba monga Cowpea over Green Bean. Ndipo ngati zomwe ndimadya ndizofunikira - ndiye kuti munthu angadziwe bwanji zakudya zomwe zimalimbikitsidwa ku Khansa ya Chithokomiro ndipo ndi yankho lomwelo kwa aliyense yemwe ali ndi matenda omwewo kapena chiwopsezo cha majini?

Inde! Zakudya zomwe mumadya ndizofunikira pa Khansa ya Chithokomiro!

Malingaliro a zakudya sangakhale ofanana kwa aliyense ndipo akhoza kukhala osiyana ngakhale pa matenda omwewo komanso chiopsezo cha majini.

Zakudya zonse (masamba, zipatso, mtedza, mbewu, phala, mafuta ndi zina) ndi zakudya zopatsa thanzi zimapangidwa ndi mamolekyulu opitilira imodzi kapena zogwira ntchito mosiyanasiyana komanso kuchuluka kwake. Chilichonse chogwiritsidwa ntchito chimakhala ndi njira yapadera yochitirapo kanthu - yomwe imatha kuyambitsa kapena kuletsa njira zosiyanasiyana zama biochemical. Zakudya zongotchulidwa mwachidule ndi zowonjezera zomwe zimalimbikitsidwa ndizomwe sizimayambitsa kuchuluka kwa maselo oyambitsa khansa koma zimawachepetsa. Apo ayi zakudya zimenezo siziyenera kuvomerezedwa. Zakudya zimakhala ndi zosakaniza zingapo zomwe zimagwira ntchito - chifukwa chake powunika zakudya ndi zowonjezera, muyenera kuganizira momwe zosakaniza zonse zimakhudzira thupi limodzi osati payekhapayekha.

Mwachitsanzo Sea-buckthornberry ili ndi zosakaniza zogwira ntchito monga Lycopene, Catechol, Caffeine, Lupeol, Cinnamaldehyde. Ndipo Black Mulberry ili ndi zosakaniza zomwe zimagwira ntchito monga Quercetin, Catechol, Morusin, Lupeol, Cinnamaldehyde ndipo mwina ena.

Kulakwitsa kofala komwe kumachitika posankha ndikusankha zakudya zoyenera kudya chifukwa cha Khansa ya Chithokomiro - ndikuwunika zosankhidwa zokha zomwe zili muzakudya ndikunyalanyaza zina. Chifukwa zosakaniza zosiyanasiyana zomwe zili muzakudya zitha kukhala ndi zotsatira zotsutsana ndi oyendetsa khansa - simungathe kusankha zosakaniza zomwe zimagwira ntchito muzakudya ndi zowonjezera kuti mupange chisankho chazakudya za Khansa ya Chithokomiro.

INDE - ZOSANKHA CHAKUDYA NDINKHANI PA KANSA. ZINSINSI ZA KALERE ZIYENERA KUGANIZIRA ZONSE ZONSE ZOKHUDZA ZOKHUDZA ZAKUDYA.

Maluso Ofunika Pakupanga Chakudya Chake pa Khansa ya Chithokomiro?

Zakudya zokometsera zamakhansa ngati Khansa ya Chithokomiro zimakhala ndi zakudya / zowonjezera; zakudya zosavomerezeka / zowonjezera zomwe zili ndi maphikidwe achitsanzo omwe amaika patsogolo kugwiritsa ntchito zakudya zoyenera. Chitsanzo cha kadyedwe kake kamakonda kuwoneka pa izi kugwirizana.

Kusankha zakudya zomwe zimalangizidwa kapena ayi ndizovuta kwambiri, zomwe zimafuna ukatswiri mu Biology ya Chithokomiro cha Khansa, sayansi yazakudya, majini, biochemistry komanso kumvetsetsa bwino momwe chithandizo cha khansa chimagwirira ntchito komanso zovuta zina zomwe chithandizocho chingasiye kugwira ntchito.

ZOCHEPA ZODZIWA ZOCHEPA ZOFUNIKA KUTI MUZITHANDIZA KUKHALA KWA MANKHWALA A KANSA NDI: CANCER BIOLOGY, FOOD SAYANSI, MANKHWALA A KANSA NDI MA GENETICS.

Makhalidwe a khansa ngati Khansa ya Chithokomiro

Makhansa onse ngati Khansa ya Chithokomiro amatha kudziwika ndi njira zapadera za biochemical - njira zosainira za Khansa ya Chithokomiro. Njira zama biochemical monga RAS-RAF Signaling, Inositol Phosphate Signaling, MAPK Signaling, PI3K-AKT-MTOR Signaling ndi gawo la matanthauzo a siginecha ya Khansa ya Chithokomiro. Mitundu ya khansa ya munthu aliyense imatha kukhala yosiyana chifukwa chake siginecha yawo yeniyeni ya khansa imatha kukhala yapadera.

Chithandizo chomwe chili chothandiza pa Khansa ya Chithokomiro chikuyenera kuzindikirika ndi ma signature a biochemical omwe amagwirizana nawo kwa wodwala khansa aliyense komanso munthu yemwe ali pachiwopsezo cha majini. Choncho mankhwala osiyanasiyana omwe ali ndi njira zosiyanasiyana zochitira zinthu ndi othandiza kwa odwala osiyanasiyana. Momwemonso komanso pazifukwa zomwezo zakudya ndi zowonjezera ziyenera kukhala zamunthu aliyense payekha. Chifukwa chake zakudya zina ndi zowonjezera zimalimbikitsidwa ku Khansa ya Chithokomiro mukamamwa mankhwala a khansa ya Dabrafenib, ndipo zakudya zina ndi zowonjezera sizovomerezeka.

Magwero ngati cBioPortal ndipo ena ambiri amapereka deta yosadziwika ya odwala omwe ali ndi chiwerengero cha anthu omwe amachokera ku mayesero a zachipatala pa zizindikiro zonse za khansa. Izi zili ndi tsatanetsatane wa kafukufuku wazachipatala monga kukula kwa zitsanzo / kuchuluka kwa odwala, magulu azaka, jenda, fuko, chithandizo, malo otupa ndi masinthidwe aliwonse.

BRAF, TERT, NRAS, EIF1AX ndi ATM ndi omwe ali pamwamba pa chibadwa cha khansa ya chithokomiro. BRAF imanenedwa mu 15.8% ya odwala oyimira m'mayesero onse azachipatala. Ndipo TERT imanenedwa mu 15.2%. Deta yophatikizidwa ya odwala imaphimba zaka kuyambira 22 mpaka 87. 51.5 % ya data ya odwala amadziwika kuti ndi amuna. Biology ya Khansa ya Chithokomiro pamodzi ndi ma genetics pamodzi amatanthauzira kuchuluka kwa anthu omwe amayimiridwa ndi njira zama biochemical za khansa iyi. Ngati chibadwa cha khansa ya munthu kapena majini omwe amathandizira pachiwopsezo amadziwikanso ndiye kuti ayenera kugwiritsidwanso ntchito pakusintha zakudya.

ZOSANKHA ZA KALERE ZIYENERA KUGWIRITSA NTCHITO NDI SIZINI YA KANSA YA MUNTHU ALIYENSE.

Chakudya ndi Zowonjezera pa Khansa ya Chithokomiro

Kwa Odwala Khansa

Odwala khansa omwe ali ndi chithandizo chamankhwala kapena ochepetsa chithandizo chamankhwala amayenera kupanga zisankho pazakudya ndi zowonjezera - pazakudya zopatsa thanzi, kuthana ndi zovuta zilizonse komanso kuwongolera kasamalidwe ka khansa. Zakudya zonse zozikidwa pamasamba sizofanana ndipo kusankha ndikuyika patsogolo zakudya zomwe zimasankhidwa payekhapayekha komanso zomwe zimasinthidwa kuti zigwiritsidwe ntchito ndi khansa ndizofunikira komanso zovuta. Nazi zitsanzo zopereka malangizo opangira zisankho za kadyedwe.

Sankhani masamba a CAULIFLOWER kapena KALE?

Kolifulawa wamasamba ali ndi zinthu zambiri zogwira ntchito kapena bioactives monga Catechol, Lupeol, Cinnamaldehyde, Curcumin, Formononetin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga MAPK Signaling, Cell Survival, Angiogenesis ndi Cell Junctions ndi ena. Kolifulawa amalangizidwa ku Khansa ya Chithokomiro pamene chithandizo cha khansa nthawi zonse ndi Dabrafenib. Izi zili choncho chifukwa Kolifulawa amasintha njira za biochemical zomwe zanenedwa mwasayansi kuti zidziwitse zotsatira za Dabrafenib.

Zina mwazinthu zomwe zimagwira ntchito kapena ma bioactive mu masamba a Kale ndi Catechol, Lupeol, Cinnamaldehyde, Curcumin, Protocatechuic Acid. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga DNA Repair ndi Oxidative Stress ndi zina. Kale sivomerezedwa ku Khansa ya Chithokomiro pamene chithandizo cha khansa chikupitirirabe ndi Dabrafenib chifukwa chimasintha njira za biochemical zomwe zimapangitsa kuti chithandizo cha khansa chisagwirizane kapena chisamayankhe.

KAULIFWA WA MASABATA AMAKONZEDWA PA KALE PA Khansa Yachithokomiro NDI Mchiritsi Dabrafenib.

Sankhani Zipatso BLACK MULBERRY kapena SEA-BUCKTHORNBERRY?

Zipatso za Black Mabulosi zimakhala ndi zinthu zambiri zomwe zimagwira ntchito kapena bioactives monga Quercetin, Catechol, Morusin, Lupeol, Cinnamaldehyde. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga kukonza DNA, Angiogenesis ndi Kupulumuka kwa Ma cell ndi ena. Black Mabulosi amalangizidwa ku Khansa ya Chithokomiro pomwe chithandizo cha khansa chopitilira ndi Dabrafenib. Izi zili choncho chifukwa Black Mulberry imasintha njira za biochemical zomwe zanenedwa mwasayansi kuti zidziwitse zotsatira za Dabrafenib.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu zipatso za Sea-buckthornberry ndi Lycopene, Catechol, Caffeine, Lupeol, Cinnamaldehyde. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga DNA Repair ndi Oxidative Stress ndi zina. Sea-buckthornberry sivomerezedwa ku Khansa ya Chithokomiro pamene chithandizo cha khansa chikupitirirabe ndi Dabrafenib chifukwa chimasintha njira za biochemical zomwe zimapangitsa kuti chithandizo cha khansa chisagwirizane kapena chisamayankhe.

ZIPATSO WAKUBILA WA CHIPATSO AMAKONZEDWA PA SEA-BUCKTHORNBERRY PA Khansa ya Chithokomiro NDI Mchiritsi wa Dabrafenib.

Sankhani Nut BUTTERNUT kapena FLEXSEED?

Butternut imakhala ndi zinthu zambiri zogwira ntchito kapena bioactives monga Lycopene, Catechol, Caffeine, Lupeol, Cinnamaldehyde. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga kukonza kwa DNA, Kukula kwa Factor Signaling, Inositol Phosphate Signaling ndi TGFB Signaling ndi ena. Butternut amalangizidwa ku Khansa ya Chithokomiro pamene chithandizo cha khansa chopitilira ndi Dabrafenib. Izi zili choncho chifukwa Butternut amasintha njira za biochemical zomwe zanenedwa mwasayansi kuti zidziwitse zotsatira za Dabrafenib.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu Flaxseed ndi Catechol, Lupeol, Cinnamaldehyde, Curcumin, Protocatechuic Acid. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Cytoskeletal Dynamics, Cell Junctions ndi Oxidative Stress ndi ena. Flaxseed siyovomerezeka kwa Khansa ya Chithokomiro pomwe chithandizo cha khansa chikupitilira ndi Dabrafenib chifukwa chimasintha njira zama biochemical zomwe zimapangitsa kuti chithandizo cha khansa chisamve kapena kuyankha.

BUTTERNUT AMADALITSIDWA PA FLEXSEED PA Khansa ya Chithokomiro NDI Mchiritsi wa Dabrafenib.

Kwa Anthu Amene Ali ndi Genetic Risk of Cancer

Funso lofunsidwa ndi anthu omwe ali ndi chiopsezo chotenga khansa ya chithokomiro kapena mbiri ya banja ndi "Kodi Ndiyenera Kudya Chiyani Mosiyana ndi Kale?" ndi momwe angasankhire zakudya ndi zowonjezera kuti athe kuthana ndi kuopsa kwa matendawa. Popeza pachiwopsezo cha khansa palibe chomwe chingachitike pankhani ya chithandizo - zosankha zazakudya ndi zowonjezera zimakhala zofunika komanso chimodzi mwazinthu zochepa zomwe zingatheke. Zakudya zonse zochokera ku zomera sizofanana ndipo zimatengera chibadwa chodziwika ndi siginecha ya njira - zosankha za zakudya ndi zowonjezera ziyenera kukhala zaumwini.

Sankhani Masamba GIANT BUTTERBUR kapena NAPA KABIJI?

Masamba a Giant Butterbur ali ndi zinthu zambiri zogwira ntchito kapena bioactives monga Apigenin, Curcumin, Myricetin, Lycopene, Protocatechuic Acid. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga kukonza DNA, Hypoxia, P53 Signaling ndi MYC Signaling ndi ena. Giant Butterbur ikulimbikitsidwa kuti ikhale pachiwopsezo cha Khansa ya Chithokomiro pomwe chiwopsezo chokhudzana ndi majini ndi ATM. Izi ndichifukwa choti Giant Butterbur imakulitsa njira za biochemical zomwe zimatsutsana ndi oyendetsa siginecha ake.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu masamba a Napa Kabichi ndi Curcumin, Protocatechuic Acid, Lupeol, Isoliquiritigenin, Daidzein. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga kukonza DNA, PI3K-AKT-MTOR Signaling ndi MYC Signaling ndi ena. Kabichi ya Napa sivomerezedwa ngati chiopsezo cha khansa ya chithokomiro chikugwirizana ndi chiopsezo cha chibadwa ndi ATM chifukwa chimawonjezera njira zake.

BUTTERBUR WACHIKULU WA MASWERO AKUKONZEDWA PA KABIJI WA NAPA PA ATM GENETIC RISK OF CANCER.

Sankhani Chipatso NDIMULO kapena PUMMELO?

Chipatso cha mandimu chili ndi zinthu zambiri zogwira ntchito kapena bioactives monga D-limonene, Curcumin, Linalool, Isorhamnetin, Protocatechuic Acid. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Apoptosis, P53 Signaling, MAPK Signaling ndi Cell Cycle Checkpoints ndi ena. Mandimu amalimbikitsidwa pa chiopsezo cha Khansa ya Chithokomiro pamene chiopsezo chokhudzana ndi majini ndi ATM. Izi ndichifukwa choti mandimu amawonjezera njira za biochemical zomwe zimatsutsana ndi madalaivala ake.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu chipatso Pummelo ndi Apigenin, Curcumin, Quercetin, Lycopene, Protocatechuic Acid. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga kukonza DNA, PI3K-AKT-MTOR Signaling ndi MYC Signaling ndi ena. Pummelo ali osavomerezeka pamene chiopsezo cha chithokomiro Khansa pamene kugwirizana chibadwa chiopsezo ndi ATM chifukwa kumawonjezera siginecha njira zake.

MANDIMU WA CHIPATSO AKUKONZEDWA PA PUMMELO PA ATM GENETIC RISK OF CANCER.

Sankhani Nut BLACK WALNUT kapena EUROPEAN CHESTNUT?

Black Walnut ili ndi zinthu zambiri zogwira ntchito kapena bioactives monga Apigenin, Ellagic Acid, Curcumin, Myricetin, Quercetin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Apoptosis, P53 Signaling, MAPK Signaling ndi Cell Cycle Checkpoints ndi ena. Black Walnut akulimbikitsidwa pachiwopsezo cha Khansa ya Chithokomiro pomwe chiwopsezo cha chibadwa ndi ATM. Izi ndichifukwa choti Black Walnut imachulukitsa njira za biochemical zomwe zimatsutsana ndi oyendetsa siginecha ake.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu European Chestnut ndi Apigenin, Ellagic Acid, Curcumin, Myricetin, Quercetin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga kukonza DNA, PI3K-AKT-MTOR Signaling ndi MYC Signaling ndi ena. European Chestnut ali osavomerezeka pamene chiopsezo cha chithokomiro Khansa pamene kugwirizana chibadwa chiopsezo ndi ATM chifukwa kumawonjezera siginecha njira zake.

WALNUT WAKUDA AKUKONZEDWA PA CHESTNUT YA KU ULAYA PA ATM GENETIC RISK OF CANCER.

Pomaliza

Zakudya ndi Zowonjezera zomwe zasankhidwa ndizofunika kwambiri kwa khansa monga Khansa ya Chithokomiro. Odwala khansa ya chithokomiro komanso anthu omwe ali pachiwopsezo cha majini nthawi zonse amakhala ndi funso ili: "Ndi zakudya ndi zakudya ziti zomwe zimandilimbikitsa komanso zomwe sizili?" Pali chikhulupiliro chofala chomwe ndi lingaliro lolakwika kuti zakudya zonse zokhala ndi mbewu zitha kukhala zopindulitsa kapena ayi koma sizingakhale zovulaza. Zakudya zina ndi zowonjezera zimatha kusokoneza chithandizo cha khansa kapena kulimbikitsa madalaivala a khansa.

Pali mitundu yosiyanasiyana yazizindikiro za khansa monga Khansa ya Chithokomiro, iliyonse ili ndi chibadwa chosiyana cha chotupa chokhala ndi mitundu ina ya ma genomic pamunthu aliyense. Kuphatikiza apo, chithandizo chilichonse cha khansa ndi chemotherapy chili ndi njira yapadera yochitira. Chakudya chilichonse ngati Kolifulawa chimakhala ndi ma bioactive osiyanasiyana mosiyanasiyana, omwe amakhudza njira zosiyanasiyana zama biochemical. Tanthauzo la zakudya zamunthu payekhapayekha ndi malingaliro amunthu payekhapayekha pazowonetsa khansa, machiritso, ma genetic, moyo ndi zina. Zosankha zokhudzana ndi thanzi la khansa zimafuna kudziwa za biology ya khansa, sayansi yazakudya komanso kumvetsetsa kwamankhwala osiyanasiyana a chemotherapy. Pomaliza pakakhala kusintha kwamankhwala kapena ma genomics atsopano azindikirika - kusintha kwa zakudya kumafunika kuunikanso.

Njira yothetsera makonda a addon imapangitsa kupanga chisankho kukhala kosavuta ndikuchotsa zongoganiza poyankha funso, "Ndi zakudya ziti zomwe ndiyenera kusankha kapena kusasankha ku Khansa ya Chithokomiro?". Gulu la addon lamitundu yambiri limaphatikizapo madokotala a khansa, asayansi azachipatala, akatswiri opanga mapulogalamu ndi asayansi a data.

Zothandizira

• Msk Impact 2017
• Mawonekedwe osinthika a khansa ya metastatic adawululidwa kuchokera kwa odwala 10,000 omwe akuyembekezeka.
• Morusin imayambitsa kufa kwa maselo kudzera pakuletsa ma sign a STAT3 m'maselo a khansa ya prostate.
• Kudya mabulosi 1-deoxynojirimycin kumateteza khansa yapakhungu mu mbewa.
• Brassinin Imapondereza Kuthekera Kwa Ma cell a Lung Carcinoma Kupyolera mu Kutsekedwa kwa PI3K/Akt/mTOR Signaling Cascade.
• Malingaliro atsopano mu phospholipase D chizindikiro mu kutupa ndi khansa.
• Paederia foetida imapangitsa ntchito yolimbana ndi khansa posintha ma enzymes osintha chromatin ndikusintha mawonekedwe amtundu wa pro-inflammatory cytokine m'maselo a khansa ya prostate.
• D-Limonene imasintha kutupa, kupsinjika kwa okosijeni ndi njira ya Ras-ERK kuti iletse ngozi ya murine tumorigenesis.
• [Kuchitika kwa kuzungulira kwa chitetezo cha mthupi mu seramu yamagazi ya odwala omwe ali ndi khansa ya khomo lachiberekero asanalandire chithandizo].
• Geraniol, chigawo cha mafuta ofunikira a zomera, chimalimbikitsa maselo a khansa yamtundu wa anthu ku chithandizo cha 5-Fluorouracil.