Introduction
Zakudya za Myelodysplastic Syndrome zokhudzana ndi Therapy ziyenera kukhala zamunthu aliyense payekhapayekha komanso zimayenera kusintha ngati chithandizo cha khansa kapena chotupa chikusintha. Kusintha kwamunthu ndikusintha kuyenera kuganizira zonse zomwe zimagwira ntchito kapena ma bioactive omwe ali muzakudya zosiyanasiyana molingana ndi biology ya khansa, majini, chithandizo, moyo komanso zomwe amakonda. Chifukwa chake ngakhale zakudya ndi chimodzi mwazosankha zofunika kwambiri kwa wodwala khansa komanso munthu yemwe ali pachiwopsezo cha khansa - momwe angasankhire zakudya zomwe angadye si ntchito yophweka.
Funso lodziwika bwino lazakudya lomwe limafunsidwa ndi odwala khansa komanso anthu omwe ali pachiwopsezo cha khansa ndi - la khansa monga Therapy-related Myelodysplastic Syndrome kodi zilibe kanthu kuti ndi zakudya ziti zomwe ndimadya komanso zomwe sindidya? Kapena ngati nditsatira zakudya zochokera ku zomera ndizokwanira khansa monga Therapy-related Myelodysplastic Syndrome?
Mwachitsanzo, kodi zilibe kanthu ngati Letesi wamasamba amadyedwa kwambiri poyerekeza ndi Arrowhead? Kodi zimapanga kusiyana kulikonse ngati zipatso za Pummelo zimakondedwa kuposa Mandarin Orange (clementine, Tangerine)? Komanso ngati kusankha kofananako kumapangidwa pa mtedza/mbewu monga Butternut over Macadamia Nut komanso zamasamba monga Broad Bean over Common Bean. Ndipo ngati zomwe ndimadya zili ndi vuto - ndiye kuti munthu angadziwe bwanji zakudya zomwe zimalimbikitsidwa ndi Therapy-related Myelodysplastic Syndrome ndipo ndi yankho lomwelo kwa aliyense yemwe ali ndi matenda omwewo kapena chiwopsezo cha majini?
Inde! Zakudya zomwe mumadya ndizofunikira pa Therapy-related Myelodysplastic Syndrome!
Malingaliro a zakudya sangakhale ofanana kwa aliyense ndipo akhoza kukhala osiyana ngakhale pa matenda omwewo komanso chiopsezo cha majini.
Zakudya zonse (masamba, zipatso, mtedza, mbewu, phala, mafuta ndi zina) ndi zakudya zopatsa thanzi zimapangidwa ndi mamolekyulu opitilira imodzi kapena zogwira ntchito mosiyanasiyana komanso kuchuluka kwake. Chilichonse chogwiritsidwa ntchito chimakhala ndi njira yapadera yochitirapo kanthu - yomwe imatha kuyambitsa kapena kuletsa njira zosiyanasiyana zama biochemical. Zakudya zongotchulidwa mwachidule ndi zowonjezera zomwe zimalimbikitsidwa ndizomwe sizimayambitsa kuchuluka kwa maselo oyambitsa khansa koma zimawachepetsa. Apo ayi zakudya zimenezo siziyenera kuvomerezedwa. Zakudya zimakhala ndi zosakaniza zingapo zomwe zimagwira ntchito - chifukwa chake powunika zakudya ndi zowonjezera, muyenera kuganizira momwe zosakaniza zonse zimakhudzira thupi limodzi osati payekhapayekha.
Mwachitsanzo Pummelo ili ndi zinthu zogwira ntchito Apigenin, Curcumin, Lycopene, Protocatechuic Acid, Lupeol. Ndipo Mandarin Orange (clementine, Tangerine) ali ndi zosakaniza zogwira ntchito Curcumin, Linalool, Protocatechuic Acid, Lupeol, Daidzein ndi ena.
Cholakwika chofala chomwe chimapangidwa posankha ndikusankha zakudya zoti mudye chifukwa cha Therapy-related Myelodysplastic Syndrome - ndikuwunika zomwe zasankhidwa zokha zomwe zili muzakudya ndikunyalanyaza zina. Chifukwa zosakaniza zosiyanasiyana zomwe zili muzakudya zitha kukhala ndi zotsatira zotsutsana ndi oyendetsa khansa - simungathe kusankha zosakaniza muzakudya ndi zowonjezera kuti mupange chisankho chazakudya cha Myelodysplastic Syndrome yokhudzana ndi Therapy.
INDE - ZOSANKHA CHAKUDYA NDINKHANI PA KANSA. ZINSINSI ZA KALERE ZIYENERA KUGANIZIRA ZONSE ZONSE ZOKHUDZA ZOKHUDZA ZAKUDYA.
Zakudya zamakhansa monga Therapy-related Myelodysplastic Syndrome imakhala ndi zakudya / zowonjezera; zakudya zosavomerezeka / zowonjezera zomwe zili ndi maphikidwe achitsanzo omwe amaika patsogolo kugwiritsa ntchito zakudya zoyenera. Chitsanzo cha kadyedwe kake kamakonda kuwoneka pa izi kugwirizana.
Kusankha zakudya zomwe zikulimbikitsidwa kapena ayi ndizovuta kwambiri, zomwe zimafuna ukadaulo wokhudzana ndi Therapy-Myelodysplastic Syndrome biology, sayansi yazakudya, majini, biochemistry komanso kumvetsetsa bwino momwe chithandizo cha khansa chimagwirira ntchito komanso zovuta zomwe chithandizocho chingasiye kugwira ntchito.
ZOCHEPA ZODZIWA ZOCHEPA ZOFUNIKA KUTI MUZITHANDIZA KUKHALA KWA MANKHWALA A KANSA NDI: CANCER BIOLOGY, FOOD SAYANSI, MANKHWALA A KANSA NDI MA GENETICS.
Zakudya Zoti Mudye Mukatha Kuzindikira Khansa!
Palibe khansa ziwiri zomwezi. Pitani kupitilira malangizo omwe anthu onse amapereka kwa onse ndikupanga zisankho zomwe mungakonde pazakudya ndi zowonjezera ndi chidaliro.
Makhansa onse monga Therapy-related Myelodysplastic Syndrome amatha kudziwika ndi njira zapadera za biochemical - njira zosainira za Therapy-related Myelodysplastic Syndrome. Njira zama biochemical monga PI3K-AKT-MTOR Signaling, mRNA Splicing, Oncogenic Cancer Epigenetics, Cell Cycle Checkpoints ndi gawo la tanthauzo la Therapy-related Myelodysplastic Syndrome. Mitundu ya khansa ya munthu aliyense imatha kukhala yosiyana chifukwa chake siginecha yawo yeniyeni ya khansa imatha kukhala yapadera.
Mankhwala omwe ali othandiza pa Therapy-related Myelodysplastic Syndrome akuyenera kuzindikira njira zomwe zimagwirizana ndizomwe zimachitika kwa wodwala khansa aliyense komanso munthu yemwe ali pachiwopsezo cha majini. Choncho mankhwala osiyanasiyana omwe ali ndi njira zosiyanasiyana zochitira zinthu ndi othandiza kwa odwala osiyanasiyana. Momwemonso komanso pazifukwa zomwezo zakudya ndi zowonjezera ziyenera kukhala zamunthu aliyense payekhapayekha. Chifukwa chake zakudya zina ndi zowonjezera zimalimbikitsidwa pa Therapy-related Myelodysplastic Syndrome mukamamwa mankhwala a khansa a Fludarabine, ndipo zakudya zina ndi zowonjezera sizovomerezeka.
Magwero ngati cBioPortal ndipo ena ambiri amapereka deta yosadziwika ya odwala omwe ali ndi chiwerengero cha anthu omwe amachokera ku mayesero a zachipatala pa zizindikiro zonse za khansa. Izi zili ndi tsatanetsatane wa kafukufuku wazachipatala monga kukula kwa zitsanzo / kuchuluka kwa odwala, magulu azaka, jenda, fuko, chithandizo, malo otupa ndi masinthidwe aliwonse.
TP53, TET2, ASXL1, EZH2 ndi ZRSR2 ndi omwe ali pamwamba pa majini omwe adanenedwa a Therapy-related Myelodysplastic Syndrome. TP53 imanenedwa mu 63.6% ya odwala oyimira m'mayesero onse azachipatala. Ndipo TET2 idanenedwa mu 27.3%. Deta yophatikizidwa ya odwala imakhudza zaka kuyambira mpaka . 0.0% ya data ya odwala amadziwika kuti ndi amuna. Therapy-related Myelodysplastic Syndrome biology pamodzi ndi ma genetics omwe amafotokozedwa palimodzi amatanthauzira kuchuluka kwa anthu omwe amayimira njira zama biochemical za khansa iyi. Ngati chibadwa cha khansa ya munthu kapena majini omwe amathandizira pachiwopsezo amadziwikanso ndiye kuti ayenera kugwiritsidwanso ntchito pakusintha zakudya.
ZOSANKHA ZA KALERE ZIYENERA KUGWIRITSA NTCHITO NDI SIZINI YA KANSA YA MUNTHU ALIYENSE.
Kwa Odwala Khansa
Odwala khansa omwe ali ndi chithandizo chamankhwala kapena ochepetsa chithandizo chamankhwala amayenera kupanga zisankho pazakudya ndi zowonjezera - pazakudya zopatsa thanzi, kuthana ndi zovuta zilizonse komanso kuwongolera kasamalidwe ka khansa. Zakudya zonse zozikidwa pamasamba sizofanana ndipo kusankha ndikuyika patsogolo zakudya zomwe zimasankhidwa payekhapayekha komanso zomwe zimasinthidwa kuti zigwiritsidwe ntchito ndi khansa ndizofunikira komanso zovuta. Nazi zitsanzo zopereka malangizo opangira zisankho za kadyedwe.
Sankhani LETTUCE yamasamba kapena ARROWHEAD?
Letesi wamasamba ali ndi zinthu zambiri zogwira ntchito kapena bioactives monga Curcumin, Protocatechuic Acid, Lupeol, Daidzein, Formononetin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Apoptosis, PI3K-AKT-MTOR Signaling ndi MYC Signaling ndi ena. Letesi akulimbikitsidwa kwa Therapy-related Myelodysplastic Syndrome pamene chithandizo cha khansa chopitirira ndi Fludarabine. Izi ndichifukwa chakuti Letesi amasintha njira za biochemical zomwe zanenedwa mwasayansi kuti zidziwitse zotsatira za Fludarabine.
Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu masamba a Arrowhead ndi Apigenin, Curcumin, Lycopene, Protocatechuic Acid, Lupeol. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Cell Cycle Checkpoints ndi mRNA Splicing ndi ena. Arrowhead siyovomerezedwa ndi Therapy-related Myelodysplastic Syndrome pamene chithandizo cha khansa chikupitilira ndi Fludarabine chifukwa imasintha njira zama biochemical zomwe zimapangitsa kuti chithandizo cha khansa zisamve kapena kuyankha.
LETTUCE WA MASABATA AKUKONDWEREDWA PA ARROWHEAD KWA Therapy yokhudzana ndi Myelodysplastic Syndrome NDI MANKHWALA A Fludarabine.
Sankhani Chipatso MANDARIN ORANGE (CLEMENTINE, TANGERINE) kapena PUMMELO?
Chipatso cha Mandarin Orange (clementine, Tangerine) chili ndi zinthu zambiri zogwira ntchito kapena bioactives monga Curcumin, Linalool, Protocatechuic Acid, Lupeol, Daidzein. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Apoptosis, P53 Signaling, MAPK Signaling ndi Cell Cycle Checkpoints ndi ena. Mandarin Orange (clementine, Tangerine) akulimbikitsidwa Therapy-related Myelodysplastic Syndrome pamene chithandizo cha khansa chopitirira ndi Fludarabine. Izi ndichifukwa choti Mandarin Orange (clementine, Tangerine) amasintha njira zama biochemical zomwe zanenedwa mwasayansi kuti zidziwitse zotsatira za Fludarabine.
Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu chipatso Pummelo ndi Apigenin, Curcumin, Lycopene, Protocatechuic Acid, Lupeol. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Cell Cycle Checkpoints, PI3K-AKT-MTOR Signaling ndi mRNA Splicing ndi ena. Pummelo siyovomerezeka pa Therapy-related Myelodysplastic Syndrome pamene chithandizo cha khansa chikupitilira ndi Fludarabine chifukwa chimasintha njira zama biochemical zomwe zimapangitsa kuti chithandizo cha khansa zisamve kapena kuyankha.
CHIPATSO MANDARIN ORANGE (CLEMENTINE, TANGERINE) AKUTHANDIZANI KUPANDA PUMMELO KWA Thandizo la Myelodysplastic Syndrome NDI MANKHWALA OCHITA Fludarabine.
Sankhani Nut BUTTERNUT kapena MACADAMIA NUT?
Butternut imakhala ndi zinthu zambiri zogwira ntchito kapena bioactives monga Apigenin, Curcumin, Lycopene, Protocatechuic Acid, Lupeol. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Apoptosis, P53 Signaling, MAPK Signaling ndi MYC Signaling ndi ena. Butternut imalimbikitsidwa pa Therapy-related Myelodysplastic Syndrome pamene chithandizo cha khansa chopitirira ndi Fludarabine. Izi ndichifukwa choti Butternut imasintha njira zama biochemical zomwe zanenedwa mwasayansi kuti zidziwitse mphamvu ya Fludarabine.
Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu Macadamia Nut ndi Apigenin, Curcumin, Protocatechuic Acid, Lupeol, Daidzein. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga MAPK Signaling ndi PI3K-AKT-MTOR Signaling ndi ena. Mtedza wa Macadamia ndiwosavomerezeka pa Therapy-related Myelodysplastic Syndrome pamene chithandizo cha khansa chikuchitika ndi Fludarabine chifukwa chimasintha njira za biochemical zomwe zimapangitsa kuti chithandizo cha khansa zisawonongeke kapena kuti chisamayankhe.
BUTTERNUT AMAKONZEDWA PA NTHAWI YA MACADAMIA PA Chithandizo chokhudzana ndi Myelodysplastic Syndrome NDI MANKHWALA A Fludarabine.
Kwa Anthu Amene Ali ndi Genetic Risk of Cancer
Funso lofunsidwa ndi anthu omwe ali ndi chiopsezo cha chibadwa cha Therapy-related Myelodysplastic Syndrome kapena mbiri ya banja ndi "Kodi Ndiyenera Kudya Chiyani Mosiyana ndi Kale?" ndi momwe angasankhire zakudya ndi zowonjezera kuti athe kuthana ndi kuopsa kwa matendawa. Popeza pachiwopsezo cha khansa palibe chomwe chingachitike pankhani ya chithandizo - zosankha zazakudya ndi zowonjezera zimakhala zofunika komanso chimodzi mwazinthu zochepa zomwe zingatheke. Zakudya zonse zochokera ku zomera sizofanana ndipo zimatengera chibadwa chodziwika ndi siginecha ya njira - zosankha za zakudya ndi zowonjezera ziyenera kukhala zaumwini.
Sankhani Masamba CALABASH kapena YAM?
Calabash yamasamba imakhala ndi zinthu zambiri zogwira ntchito kapena bioactives monga Apigenin, Curcumin, Formononetin, Lupeol, Daidzein. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga JAK-STAT Signaling, P53 Signaling, MAPK Signaling ndi Cell Cycle Checkpoints ndi ena. Calabash amalangizidwa pachiwopsezo cha Therapy-related Myelodysplastic Syndrome pomwe chiwopsezo chokhudzana ndi majini ndi ASXL1. Izi ndichifukwa choti Calabash imawonjezera njira za biochemical zomwe zimatsutsana ndi oyendetsa siginecha ake.
Zina mwazinthu zomwe zimagwira ntchito kapena ma bioactive mu masamba a Yam ndi Apigenin, Curcumin, Formononetin, Lupeol, Daidzein. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Oxidative Stress ndi Oncogenic Cancer Epigenetics ndi ena. Chilazi sichivomerezedwa ngati chiopsezo cha Therapy-related Myelodysplastic Syndrome pamene chiwopsezo chokhudzana ndi majini ndi ASXL1 chifukwa chimawonjezera njira zake.
VEGETABLE CALABASH AMAKONZEDWA PA YAM PA ASXL1 GENETIC RISK OF CANCER.
Sankhani Chipatso WATERMELON kapena ALASKA BLUEBERRY?
Chivwende cha Chipatso chimakhala ndi zinthu zambiri zogwira ntchito kapena bioactives monga Curcumin, Formononetin, Lupeol, Daidzein, Bergapten. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga JAK-STAT Signaling, P53 Signaling, MAPK Signaling ndi Cell Cycle Checkpoints ndi ena. Chivwende chikulimbikitsidwa kuti chikhale pachiwopsezo cha Therapy-related Myelodysplastic Syndrome pomwe chiwopsezo chokhudzana ndi majini ndi ASXL1. Izi ndichifukwa choti Watermelon imachulukitsa njira za biochemical zomwe zimatsutsana ndi madalaivala ake.
Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu zipatso za Alaska Blueberry ndi Apigenin, Curcumin, Formononetin, Lupeol, Daidzein. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Oxidative Stress ndi Oncogenic Cancer Epigenetics ndi ena. Alaska Blueberry sivomerezedwa ngati chiopsezo cha Therapy-related Myelodysplastic Syndrome pamene chiwopsezo cha chibadwa ndi ASXL1 chifukwa chimawonjezera njira zake.
MAWIRI WA CHIPATSO AKUKONZEDWA PA ALASKA BLUEBERRY PA ASXL1 GENETIC RISK OF CANCER.
Sankhani Nut COMMON HAZELNUT kapena CHESTNUT?
Mtedza wamba uli ndi zinthu zambiri zogwira ntchito kapena bioactives monga Curcumin, Quercetin, Formononetin, Lupeol, Daidzein. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga JAK-STAT Signaling, P53 Signaling, MAPK Signaling ndi Cell Cycle Checkpoints ndi ena. Common Hazelnut akulimbikitsidwa kuti pakhale chiopsezo cha Therapy-related Myelodysplastic Syndrome pamene chiopsezo chokhudzana ndi majini ndi ASXL1. Izi ndichifukwa choti Common Hazelnut imachulukitsa njira zama biochemical zomwe zimatsutsana ndi madalaivala ake.
Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu Chestnut ndi Apigenin, Curcumin, Ellagic Acid, Formononetin, Lupeol. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Oxidative Stress ndi Oncogenic Cancer Epigenetics ndi ena. Chestnut sichivomerezedwa ngati chiopsezo cha Therapy-related Myelodysplastic Syndrome pamene chiwopsezo chokhudzana ndi majini ndi ASXL1 chifukwa chimawonjezera njira zake.
COMMON HAZELNUT AMAKONZEDWA PA CHESTNUT PA ASXL1 GENETIC RISK YA KANSA.
Pomaliza
Zakudya ndi Zowonjezera zomwe zasankhidwa ndi zosankha zofunika pa khansa monga Therapy-related Myelodysplastic Syndrome. Odwala okhudzana ndi chithandizo cha Myelodysplastic Syndrome komanso anthu omwe ali pachiwopsezo cha majini nthawi zonse amakhala ndi funso ili: "Ndi zakudya ziti ndi zakudya zowonjezera zomwe zimandilimbikitsa komanso zomwe sizili?" Pali chikhulupiliro chofala chomwe ndi lingaliro lolakwika kuti zakudya zonse zokhala ndi mbewu zitha kukhala zopindulitsa kapena ayi koma sizingakhale zovulaza. Zakudya zina ndi zowonjezera zimatha kusokoneza chithandizo cha khansa kapena kulimbikitsa madalaivala a khansa.
Pali mitundu yosiyanasiyana yazizindikiro za khansa monga Therapy-related Myelodysplastic Syndrome, iliyonse ili ndi chibadwa cha chotupa chosiyana ndi ma genomic osiyanasiyana pamunthu aliyense. Kuphatikiza apo, chithandizo chilichonse cha khansa ndi chemotherapy chili ndi njira yapadera yochitira. Chakudya chilichonse ngati Letesi chimakhala ndi ma bioactive osiyanasiyana mosiyanasiyana, omwe amakhudza njira zosiyanasiyana zama biochemical. Tanthauzo la zakudya zamunthu payekhapayekha ndi malingaliro amunthu payekhapayekha pazowonetsa khansa, machiritso, ma genetic, moyo ndi zina. Zosankha zokhudzana ndi thanzi la khansa zimafuna kudziwa za biology ya khansa, sayansi yazakudya komanso kumvetsetsa kwamankhwala osiyanasiyana a chemotherapy. Pomaliza pakakhala kusintha kwamankhwala kapena ma genomics atsopano azindikirika - kusintha kwa zakudya kumafunika kuunikanso.
Njira yothetsera makonda a addon imapangitsa kupanga chisankho kukhala kosavuta ndikuchotsa malingaliro onse poyankha funso, "Ndi zakudya ziti zomwe ndiyenera kusankha kapena kusasankha pa Therapy-related Myelodysplastic Syndrome?". Gulu la addon lamitundu yambiri limaphatikizapo madokotala a khansa, asayansi azachipatala, akatswiri opanga mapulogalamu ndi asayansi a data.
Zakudya Zawekha za Khansa!
Khansara imasintha ndi nthawi. Sinthani ndikusintha zakudya zanu kutengera zomwe zikuwonetsa khansa, machiritso, moyo, zomwe mumakonda, zomwe zingakusangalatseni ndi zina.
Zothandizira
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- Formononetin imachepetsa kuchulukira kwa khansa ya m'mapapo ya anthu yomwe si yaing'ono ya m'mapapo kudzera pakuphatikizidwa kwa kumangidwa kwa ma cell ndi apoptosis.