Zakudya za Systemic Mastocytosis!

Introduction

Zakudya za Systemic Mastocytosis ziyenera kukhala zamunthu aliyense payekhapayekha komanso zimayenera kusintha ngati chithandizo cha khansa kapena chotupa chikusintha. Kusintha kwamunthu ndikusintha kuyenera kuganizira zonse zomwe zimagwira ntchito kapena ma bioactive omwe ali muzakudya zosiyanasiyana molingana ndi biology ya khansa, majini, chithandizo, moyo komanso zomwe amakonda. Chifukwa chake ngakhale zakudya ndi chimodzi mwazosankha zofunika kwambiri kwa wodwala khansa komanso munthu yemwe ali pachiwopsezo cha khansa - momwe angasankhire zakudya zomwe angadye si ntchito yophweka.

Kwa Systemic Mastocytosis kodi zili ndi masamba, zipatso, mtedza, mbewu zomwe munthu amadya?

Funso lodziwika bwino lazakudya lomwe limafunsidwa ndi odwala khansa komanso anthu omwe ali pachiwopsezo cha khansa ndi - la khansa ngati Systemic Mastocytosis kodi zilibe kanthu kuti ndikudya chiyani komanso zomwe sindidya? Kapena ngati nditsatira zakudya zochokera ku zomera ndizokwanira khansa monga Systemic Mastocytosis?

Mwachitsanzo, kodi zilibe kanthu ngati masamba a Brussel Sprout amadyedwa kwambiri poyerekeza ndi mpiru? Kodi zimapanga kusiyana kulikonse ngati Mkuyu wa zipatso umakondedwa kuposa Rabbiteye Blueberry? Komanso ngati kusankha kofanana kumapangidwira mtedza/mbewu monga Walnut Wakuda pamwamba pa Chestnut komanso zokometsera monga Chickpea pa Catjang Pea. Ndipo ngati zomwe ndimadya zili ndi vuto - ndiye kuti munthu angadziwe bwanji zakudya zomwe zimalimbikitsidwa ku Systemic Mastocytosis ndipo ndi yankho lomwelo kwa aliyense yemwe ali ndi matenda omwewo kapena chiwopsezo cha chibadwa?

Inde! Zakudya zomwe mumadya ndizofunikira pa Systemic Mastocytosis!

Malingaliro a zakudya sangakhale ofanana kwa aliyense ndipo akhoza kukhala osiyana ngakhale pa matenda omwewo komanso chiopsezo cha majini.

Zakudya zonse (masamba, zipatso, mtedza, mbewu, phala, mafuta ndi zina) ndi zakudya zopatsa thanzi zimapangidwa ndi mamolekyulu opitilira imodzi kapena zogwira ntchito mosiyanasiyana komanso kuchuluka kwake. Chilichonse chogwiritsidwa ntchito chimakhala ndi njira yapadera yochitirapo kanthu - yomwe imatha kuyambitsa kapena kuletsa njira zosiyanasiyana zama biochemical. Zakudya zongotchulidwa mwachidule ndi zowonjezera zomwe zimalimbikitsidwa ndizomwe sizimayambitsa kuchuluka kwa maselo oyambitsa khansa koma zimawachepetsa. Apo ayi zakudya zimenezo siziyenera kuvomerezedwa. Zakudya zimakhala ndi zosakaniza zingapo zomwe zimagwira ntchito - chifukwa chake powunika zakudya ndi zowonjezera, muyenera kuganizira momwe zosakaniza zonse zimakhudzira thupi limodzi osati payekhapayekha.

Mwachitsanzo mkuyu uli ndi zosakaniza yogwira Isoliquiritigenin, Quercetin, Kaempferol, Taxifolin, Curcumin. Ndipo Rabbiteye Blueberry ili ndi zinthu zomwe zimagwira ntchito monga Quercetin, Linalool, Geraniol, Gallic Acid, Ferulic Acid ndi ena.

Kulakwitsa kofala komwe kumachitika posankha ndikusankha zakudya zodyera za Systemic Mastocytosis - ndikuwunika zosankhidwa zokha zomwe zili muzakudya ndikunyalanyaza zina zonse. Chifukwa zosakaniza zosiyanasiyana zomwe zili muzakudya zitha kukhala ndi zotsatira zotsutsana ndi oyendetsa khansa - simungathe kusankha zosakaniza muzakudya ndi zowonjezera kuti mupange chisankho chazakudya cha Systemic Mastocytosis.

INDE - ZOSANKHA CHAKUDYA NDINKHANI PA KANSA. ZINSINSI ZA KALERE ZIYENERA KUGANIZIRA ZONSE ZONSE ZOKHUDZA ZOKHUDZA ZAKUDYA.

Maluso Ofunika Pakukonda Chakudya Chakudya Kwa Systemic Mastocytosis?

Zakudya zamakhansa monga Systemic Mastocytosis zimakhala ndi zakudya / zowonjezera; zakudya zosavomerezeka / zowonjezera zomwe zili ndi maphikidwe achitsanzo omwe amaika patsogolo kugwiritsa ntchito zakudya zoyenera. Chitsanzo cha kadyedwe kake kamakonda kuwoneka pa izi kugwirizana.

Kusankha zakudya zomwe zikulimbikitsidwa kapena ayi ndizovuta kwambiri, zomwe zimafuna ukadaulo wa Systemic Mastocytosis biology, sayansi yazakudya, majini, biochemistry komanso kumvetsetsa bwino momwe chithandizo cha khansa chimagwirira ntchito komanso zovuta zina zomwe mankhwalawo angasiye kugwira ntchito.

ZOCHEPA ZODZIWA ZOCHEPA ZOFUNIKA KUTI MUZITHANDIZA KUKHALA KWA MANKHWALA A KANSA NDI: CANCER BIOLOGY, FOOD SAYANSI, MANKHWALA A KANSA NDI MA GENETICS.

Makhalidwe a khansa monga Systemic Mastocytosis

Makhansa onse monga Systemic Mastocytosis amatha kudziwika ndi njira zapadera za biochemical - njira zosayina za Systemic Mastocytosis. Njira zama biochemical monga JAK-STAT Signaling, MAPK Signaling, PI3K-AKT-MTOR Signaling, RAS-RAF Signaling ndi gawo la tanthauzo la Systemic Mastocytosis. Mitundu ya khansa ya munthu aliyense imatha kukhala yosiyana chifukwa chake siginecha yawo yeniyeni ya khansa imatha kukhala yapadera.

Chithandizo chomwe chili chothandiza pa Systemic Mastocytosis chiyenera kuzindikirika ndi ma signature a biochemical omwe amalumikizana nawo kwa wodwala khansa aliyense komanso munthu yemwe ali pachiwopsezo cha majini. Choncho mankhwala osiyanasiyana omwe ali ndi njira zosiyanasiyana zochitira zinthu ndi othandiza kwa odwala osiyanasiyana. Momwemonso komanso pazifukwa zomwezo zakudya ndi zowonjezera ziyenera kukhala zamunthu aliyense payekhapayekha. Chifukwa chake zakudya zina ndi zowonjezera zimalimbikitsidwa ku Systemic Mastocytosis mukamamwa mankhwala a khansa a Midostaurin, ndipo zakudya zina ndi zowonjezera sizovomerezeka.

Magwero ngati cBioPortal ndipo ena ambiri amapereka deta yosadziwika ya odwala omwe ali ndi chiwerengero cha anthu omwe amachokera ku mayesero a zachipatala pa zizindikiro zonse za khansa. Izi zili ndi tsatanetsatane wa kafukufuku wazachipatala monga kukula kwa zitsanzo / kuchuluka kwa odwala, magulu azaka, jenda, fuko, chithandizo, malo otupa ndi masinthidwe aliwonse.

CNOT3, DNMT3A, FLT3, NPM1 ndi KIT ndi omwe ali pamwamba pa jini za Systemic Mastocytosis. CNOT3 imanenedwa mu 50.0% ya odwala oyimira m'mayesero onse azachipatala. Ndipo DNMT3A imanenedwa mu 50.0 %. Deta yophatikizidwa ya odwala imakhudza zaka kuyambira mpaka . 100.0 % ya data ya odwala amadziwika kuti ndi amuna. The Systemic Mastocytosis biology limodzi ndi ma genetics omwe adanenedwa palimodzi amafotokozera kuchuluka kwa anthu omwe amayimira njira zama biochemical za khansa iyi. Ngati chibadwa cha khansa ya munthu kapena majini omwe amathandizira pachiwopsezo amadziwikanso ndiye kuti ayenera kugwiritsidwanso ntchito pakusintha zakudya.

ZOSANKHA ZA KALERE ZIYENERA KUGWIRITSA NTCHITO NDI SIZINI YA KANSA YA MUNTHU ALIYENSE.

Zakudya ndi Zowonjezera za Systemic Mastocytosis

Kwa Odwala Khansa

Odwala khansa omwe ali ndi chithandizo chamankhwala kapena ochepetsa chithandizo chamankhwala amayenera kupanga zisankho pazakudya ndi zowonjezera - pazakudya zopatsa thanzi, kuthana ndi zovuta zilizonse komanso kuwongolera kasamalidwe ka khansa. Zakudya zonse zozikidwa pamasamba sizofanana ndipo kusankha ndikuyika patsogolo zakudya zomwe zimasankhidwa payekhapayekha komanso zomwe zimasinthidwa kuti zigwiritsidwe ntchito ndi khansa ndizofunikira komanso zovuta. Nazi zitsanzo zopereka malangizo opangira zisankho za kadyedwe.

Sankhani Masamba a BRUSSEL sprouts kapena TURNIP?

Masamba a Brussel Sprout ali ndi zinthu zambiri zogwira ntchito kapena bioactives monga Isoliquiritigenin, Taxifolin, Sulforaphane, Curcumin, Lupeol. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga PI3K-AKT-MTOR Signaling, MAPK Signaling, Oncogenic Cancer Epigenetics ndi MYC Signaling ndi ena. Brussel Sprouts akulimbikitsidwa kwa Systemic Mastocytosis pamene chithandizo cha khansa chikuchitika ndi Midostaurin. Izi ndichifukwa choti Brussel Sprouts imasintha njira zama biochemical zomwe zanenedwa mwasayansi kuti zidziwitse mphamvu ya Midostaurin.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu Turnip ya masamba ndi Isoliquiritigenin, Quercetin, Kaempferol, Taxifolin, Ellagic Acid. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga MYC Signaling, MAPK Signaling ndi PI3K-AKT-MTOR Signaling ndi ena. Turnip siyovomerezeka kwa Systemic Mastocytosis pamene chithandizo cha khansa chikupitilira ndi Midostaurin chifukwa chimasintha njira za biochemical zomwe zimapangitsa kuti chithandizo cha khansa chisamve kapena kuyankha.

Mphukira ZOPHUNZITSIRA ZA BRUSSEL AMAKONDWELEKA PAMBUYO YOTSATIRA NTCHITO YA Systemic Mastocytosis NDI MANKHWALA A Midostaurin.

Sankhani Zipatso RABBITEYE BLUEBERRY kapena FIG?

Zipatso za Blueberry Zipatso zimakhala ndi zinthu zambiri zogwira ntchito kapena bioactives monga Quercetin, Linalool, Geraniol, Gallic Acid, Ferulic Acid. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga MAPK Signaling ndi PI3K-AKT-MTOR Signaling ndi ena. Rabbiteye Blueberry akulimbikitsidwa kwa Systemic Mastocytosis pamene chithandizo cha khansa chopitilira ndi Midostaurin. Izi ndichifukwa choti Rabbiteye Blueberry amasintha njira zama biochemical zomwe zanenedwa mwasayansi kuti zidziwitse mphamvu ya Midostaurin.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu zipatso Mkuyu ndi Isoliquiritigenin, Quercetin, Kaempferol, Taxifolin, Curcumin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga MAPK Signaling ndi PI3K-AKT-MTOR Signaling ndi ena. Chikuyu sichivomerezeka kwa Systemic Mastocytosis pamene chithandizo cha khansa chikupitilira ndi Midostaurin chifukwa chimasintha njira za biochemical zomwe zimapangitsa kuti chithandizo cha khansa chisamve kapena kuyankha.

ZIPATSO RABBITEYE BLUEBERRY AMAKONZEDWA PAMKULU WA Systemic Mastocytosis NDI Mchiritsi Midostaurin.

Sankhani Nut BLACK WALNUT kapena CHESTNUT?

Black Walnut ili ndi zinthu zambiri zogwira ntchito kapena bioactives monga Apigenin, Isoliquiritigenin, Myricetin, Quercetin, Kaempferol. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga RAS-RAF Signaling, PI3K-AKT-MTOR Signaling ndi MYC Signaling ndi ena. Black Walnut akulimbikitsidwa kuti agwiritse ntchito Systemic Mastocytosis pamene chithandizo cha khansa chikuchitika ndi Midostaurin. Izi ndichifukwa choti Black Walnut imasintha njira zama biochemical zomwe zanenedwa mwasayansi kuti zidziwitse mphamvu ya Midostaurin.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu Chestnut ndi Apigenin, Isoliquiritigenin, Myricetin, Kaempferol, Luteolin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga PI3K-AKT-MTOR Signaling, Oncogenic Cancer Epigenetics ndi MYC Signaling ndi ena. Chestnut ndiyosavomerezeka kwa Systemic Mastocytosis pamene chithandizo cha khansa chikuchitika ndi Midostaurin chifukwa chimasintha njira za biochemical zomwe zimapangitsa kuti chithandizo cha khansa chisamve kapena kuyankha.

WALNUT WAKUDA AMAKONZEDWA PA CHESTNUT KWA Systemic Mastocytosis NDI MACHITIDWE A Midostaurin.

Kwa Anthu Amene Ali ndi Genetic Risk of Cancer

Funso lofunsidwa ndi anthu omwe ali ndi chiopsezo cha chibadwa cha Systemic Mastocytosis kapena mbiri ya banja ndi "Kodi Ndiyenera Kudya Chiyani Mosiyana ndi Kale?" ndi momwe angasankhire zakudya ndi zowonjezera kuti athe kuthana ndi kuopsa kwa matendawa. Popeza pachiwopsezo cha khansa palibe chomwe chingachitike pankhani ya chithandizo - zosankha zazakudya ndi zowonjezera zimakhala zofunika komanso chimodzi mwazinthu zochepa zomwe zingatheke. Zakudya zonse zochokera ku zomera sizofanana ndipo zimatengera chibadwa chodziwika ndi siginecha ya njira - zosankha za zakudya ndi zowonjezera ziyenera kukhala zaumwini.

Sankhani masamba a CAULIFLOWER kapena ARROWHEAD?

Kolifulawa wamasamba ali ndi zinthu zambiri zogwira ntchito kapena bioactives monga Isoliquiritigenin, Curcumin, Catechol, Vitamini C, Lupeol. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga PI3K-AKT-MTOR Signaling, RAS-RAF Signaling, MAPK Signaling ndi MYC Signaling ndi ena. Kolifulawa akulimbikitsidwa pachiwopsezo cha Systemic Mastocytosis pomwe chiwopsezo cha chibadwa ndi CNOT3. Izi ndichifukwa choti Kolifulawa imawonjezera njira zama biochemical zomwe zimatsutsana ndi madalaivala ake.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu masamba a Arrowhead ndi Apigenin, Myricetin, Isoliquiritigenin, Kaempferol, Luteolin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Stem Cell Signaling ndi Oncogenic Cancer Epigenetics ndi ena. Arrowhead sivomerezedwa pamene chiopsezo cha Systemic Mastocytosis pamene chiwopsezo chokhudzana ndi chibadwa chiri CNOT3 chifukwa chimawonjezera njira zake.

CAULIFLOWER YA MASAMBA AMAKONZEDWA PA ARROWHEAD PA CNOT3 GENETIC RISK OF CANCER.

Sankhani Chipatso NDIMULO kapena PUMMELO?

Chipatso cha mandimu chimakhala ndi zinthu zambiri zogwira ntchito kapena bioactives monga Isoliquiritigenin, D-limonene, Luteolin, Linalool, Curcumin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Suppressive Histone Methylation, RAS-RAF Signaling, PI3K-AKT-MTOR Signaling ndi MYC Signaling ndi ena. Ndimu akulimbikitsidwa pachiwopsezo cha Systemic Mastocytosis pomwe chiwopsezo chokhudzana ndi chibadwa ndi CNOT3. Izi ndichifukwa choti mandimu amawonjezera njira za biochemical zomwe zimatsutsana ndi madalaivala ake.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu chipatso Pummelo ndi Apigenin, Quercetin, Isoliquiritigenin, Curcumin, Lycopene. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga PI3K-AKT-MTOR Signaling ndi MYC Signaling ndi ena. Pummelo sivomerezedwa ngati chiwopsezo cha Systemic Mastocytosis chikalumikizidwa pachiwopsezo chamtundu wa CNOT3 chifukwa chimawonjezera njira zake.

MANDIMU WA CHIPATSO NDI AMAKONDWEredwa PA PUMMELO PA CNOT3 GENETIC RISK OF CANCER.

Sankhani Nut BUTTERNUT kapena EUROPEAN CHESTNUT?

Butternut imakhala ndi zinthu zambiri zogwira ntchito kapena bioactives monga Apigenin, Myricetin, Isoliquiritigenin, Kaempferol, Luteolin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga JAK-STAT Signaling, RAS-RAF Signaling, MAPK Signaling ndi MYC Signaling ndi ena. Butternut akulimbikitsidwa pachiwopsezo cha Systemic Mastocytosis pomwe chiwopsezo chokhudzana ndi chibadwa ndi CNOT3. Izi ndichifukwa choti Butternut imachulukitsa njira za biochemical zomwe zimatsutsana ndi oyendetsa siginecha ake.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu European Chestnut ndi Apigenin, Quercetin, Myricetin, Isoliquiritigenin, Kaempferol. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Stem Cell Signaling ndi Oncogenic Cancer Epigenetics ndi ena. European Chestnut sivomerezedwa ngati chiopsezo cha Systemic Mastocytosis pamene chiwopsezo cha chibadwa ndi CNOT3 chifukwa chimawonjezera njira zake.

BUTTERNUT AMAKANGALALA PA CHESTNUT YA KU ULAYA PA CNOT3 GENETIC RISK OF CANCER.

Pomaliza

Zakudya ndi Zowonjezera zomwe zasankhidwa ndi zosankha zofunika pa khansa monga Systemic Mastocytosis. Odwala a Systemic Mastocytosis komanso anthu omwe ali pachiwopsezo cha majini nthawi zonse amakhala ndi funso ili: "Ndi zakudya ziti ndi zakudya zowonjezera zomwe zimandilimbikitsa komanso zomwe sizili?" Pali chikhulupiliro chofala chomwe ndi lingaliro lolakwika kuti zakudya zonse zokhala ndi mbewu zitha kukhala zopindulitsa kapena ayi koma sizingakhale zovulaza. Zakudya zina ndi zowonjezera zimatha kusokoneza chithandizo cha khansa kapena kulimbikitsa madalaivala a khansa.

Pali mitundu yosiyanasiyana yazizindikiro za khansa monga Systemic Mastocytosis, iliyonse ili ndi chibadwa chosiyana cha chotupa chokhala ndi ma genomic osiyanasiyana pamunthu aliyense. Kuphatikiza apo, chithandizo chilichonse cha khansa ndi chemotherapy chili ndi njira yapadera yochitira. Chakudya chilichonse monga Brussel Sprouts chimakhala ndi ma bioactive osiyanasiyana mosiyanasiyana, omwe amakhudza njira zosiyanasiyana zama biochemical. Tanthauzo la zakudya zamunthu payekhapayekha ndi malingaliro amunthu payekhapayekha pazowonetsa khansa, machiritso, ma genetic, moyo ndi zina. Zosankha zokhudzana ndi thanzi la khansa zimafuna kudziwa za biology ya khansa, sayansi yazakudya komanso kumvetsetsa kwamankhwala osiyanasiyana a chemotherapy. Pomaliza pakakhala kusintha kwamankhwala kapena ma genomics atsopano azindikirika - kusintha kwa zakudya kumafunika kuunikanso.

Njira yothetsera makonda a addon imapangitsa kupanga chisankho kukhala kosavuta ndikuchotsa zongoganiza poyankha funso, "Ndi zakudya ziti zomwe ndiyenera kusankha kapena kusasankha pa Systemic Mastocytosis?". Gulu la addon lamitundu yambiri limaphatikizapo madokotala a khansa, asayansi azachipatala, akatswiri opanga mapulogalamu ndi asayansi a data.

Zothandizira

• Aml Ohsu 2018
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• D-Limonene imasintha kutupa, kupsinjika kwa okosijeni ndi njira ya Ras-ERK kuti iletse ngozi ya murine tumorigenesis.
• Kupewa kwa butyric acid, nicotinamide, calcium glucarate yokha kapena kuphatikiza pa 7, 12-dimethylbenz (a) anthracene induced mouse skin tumorigenesis kudzera modulation of K-Ras-PI3K-AKTpathway and related micro RNAs.