Zakudya za Sarcoma!

Introduction

Zakudya za Sarcoma ziyenera kukhala zamunthu payekhapayekha komanso zimayenera kusintha ngati chithandizo cha khansa kapena chotupa chikusintha. Kusintha kwamunthu ndikusintha kuyenera kuganizira zonse zomwe zimagwira ntchito kapena ma bioactive omwe ali muzakudya zosiyanasiyana molingana ndi biology ya khansa, majini, chithandizo, moyo komanso zomwe amakonda. Chifukwa chake ngakhale zakudya ndi chimodzi mwazosankha zofunika kwambiri kwa wodwala khansa komanso munthu yemwe ali pachiwopsezo cha khansa - momwe angasankhire zakudya zomwe angadye si ntchito yophweka.

Soft tissue sarcoma ndi mtundu wosowa wa khansa yomwe imakhudza minofu yosalala (leiomyosarcoma), tendon, mafuta (liposarcoma), mitsempha yamagazi ndi magazi, ndi mitsempha. Pafupifupi ma sarcoma onse akuluakulu amakula m'manja ndi m'miyendo, pachifuwa ndi m'mimba. Kuzindikira msanga ndi chithandizo kumawonjezera mwayi wokhala ndi moyo wautali. Kupulumuka kwa zaka 5 kwa akuluakulu omwe ali ndi sarcoma ndi pafupifupi 65% ndipo chiwerengero cha kupulumuka chimawonjezeka kufika pa 81% kwa anthu omwe khansa yawo imapezeka ndikuchiritsidwa isanafalikire. Amuna amatha kukhala ndi sarcoma yofewa kuposa akazi. Njira zochizira sarcoma zimaphatikizapo opaleshoni, chemotherapy, chithandizo cha radiation, chithandizo chomwe mukufuna, komanso ma immunotherapies, mothandizidwa ndi zakudya zoyenera (zakudya ndi zowonjezera zachilengedwe) zogwirizana ndi chithandizo.

Kwa Sarcoma kodi zili ndi masamba, zipatso, mtedza, mbewu zomwe munthu amadya?

Funso lodziwika bwino lazakudya lomwe limafunsidwa ndi odwala khansa komanso anthu omwe ali pachiwopsezo cha khansa ndi - kwa khansa ngati Sarcoma, kodi zilibe kanthu kuti ndi zakudya ziti zomwe ndimadya komanso zomwe sindidya? Kapena ngati nditsatira zakudya zochokera ku zomera ndizokwanira khansa ngati Sarcoma?

Mwachitsanzo, kodi zilibe kanthu ngati masamba aku New Zealand Sipinachi amadyedwa kwambiri poyerekeza ndi Sipinachi? Kodi zimapanga kusiyana kulikonse ngati zipatso za Black Elderberry zimakonda kuposa French Plantain? Komanso ngati kusankha kofananako kumapangidwira mtedza/mbewu monga Butternut pamwamba pa Chestnut komanso zokometsera ngati Gram Bean pa Catjang Pea. Ndipo ngati zomwe ndimadya zili ndi vuto - ndiye kuti munthu angadziwe bwanji zakudya zomwe zimalimbikitsidwa ku Sarcoma ndipo ndi yankho lomwelo kwa aliyense yemwe ali ndi matenda omwewo kapena chiwopsezo cha chibadwa?

Inde! Zakudya zomwe mumadya ndizofunikira kwa Sarcoma!

Malingaliro a zakudya sangakhale ofanana kwa aliyense ndipo akhoza kukhala osiyana ngakhale pa matenda omwewo komanso chiopsezo cha majini.

Zakudya zonse (masamba, zipatso, mtedza, mbewu, phala, mafuta ndi zina) ndi zakudya zopatsa thanzi zimapangidwa ndi mamolekyulu opitilira imodzi kapena zogwira ntchito mosiyanasiyana komanso kuchuluka kwake. Chilichonse chogwiritsidwa ntchito chimakhala ndi njira yapadera yochitirapo kanthu - yomwe imatha kuyambitsa kapena kuletsa njira zosiyanasiyana zama biochemical. Zakudya zongotchulidwa mwachidule ndi zowonjezera zomwe zimalimbikitsidwa ndizomwe sizimayambitsa kuchuluka kwa maselo oyambitsa khansa koma zimawachepetsa. Apo ayi zakudya zimenezo siziyenera kuvomerezedwa. Zakudya zimakhala ndi zosakaniza zingapo zomwe zimagwira ntchito - chifukwa chake powunika zakudya ndi zowonjezera, muyenera kuganizira momwe zosakaniza zonse zimakhudzira thupi limodzi osati payekhapayekha.

Mwachitsanzo Black Elderberry ili ndi zinthu zogwira ntchito Curcumin, Apigenin, Lycopene, Formononetin, Beta-sitosterol. Ndipo French Plantain ili ndi zosakaniza zomwe zimagwira ntchito monga Curcumin, Apigenin, Formononetin, Beta-sitosterol, Quercetin ndi ena.

Cholakwika chofala chomwe chimapangidwa posankha ndikusankha zakudya zoyenera kudya za Sarcoma - ndikuwunika zomwe zasankhidwa zokha zomwe zili muzakudya ndikunyalanyaza zina. Chifukwa zosakaniza zosiyanasiyana zomwe zili muzakudya zitha kukhala ndi zotsatira zotsutsana ndi oyendetsa khansa - simungathe kusankha zosakaniza muzakudya ndi zowonjezera kuti mupange chisankho cha Sarcoma.

INDE - ZOSANKHA CHAKUDYA NDINKHANI PA KANSA. ZINSINSI ZA KALERE ZIYENERA KUGANIZIRA ZONSE ZONSE ZOKHUDZA ZOKHUDZA ZAKUDYA.

Maluso Ofunika Pakukonda Chakudya Mwamakonda a Sarcoma?

Zakudya zamakhansa ngati Sarcoma zimakhala ndi zakudya / zowonjezera; zakudya zosavomerezeka / zowonjezera zomwe zili ndi maphikidwe achitsanzo omwe amaika patsogolo kugwiritsa ntchito zakudya zoyenera. Chitsanzo cha kadyedwe kake kamakonda kuwoneka pa izi kugwirizana.

Kusankha zakudya zomwe zimalangizidwa kapena ayi ndizovuta kwambiri, zomwe zimafuna ukadaulo wa Sarcoma biology, sayansi yazakudya, majini, biochemistry komanso kumvetsetsa bwino momwe chithandizo cha khansa chimagwirira ntchito komanso zovuta zina zomwe chithandizocho chingasiye kugwira ntchito.

ZOCHEPA ZODZIWA ZOCHEPA ZOFUNIKA KUTI MUZITHANDIZA KUKHALA KWA MANKHWALA A KANSA NDI: CANCER BIOLOGY, FOOD SAYANSI, MANKHWALA A KANSA NDI MA GENETICS.

Makhalidwe a khansa monga Sarcoma

Makhansa onse ngati Sarcoma amatha kudziwika ndi njira zapadera za biochemical - njira zosayina za Sarcoma. Njira zama biochemical monga Oncogenic Cancer Epigenetics, MAPK Signaling, PI3K-AKT-MTOR Signaling, Cell Cycle ndi gawo la tanthauzo la Sarcoma. Mitundu ya khansa ya munthu aliyense imatha kukhala yosiyana chifukwa chake siginecha yawo yeniyeni ya khansa imatha kukhala yapadera.

Chithandizo chomwe chili chothandiza kwa Sarcoma kuyenera kuzindikirika ndi ma signature a biochemical okhudzana ndi wodwala khansa aliyense komanso munthu yemwe ali pachiwopsezo cha majini. Choncho mankhwala osiyanasiyana omwe ali ndi njira zosiyanasiyana zochitira zinthu ndi othandiza kwa odwala osiyanasiyana. Momwemonso komanso pazifukwa zomwezo zakudya ndi zowonjezera ziyenera kukhala zamunthu aliyense payekhapayekha. Chifukwa chake zakudya zina ndi zowonjezera zimalimbikitsidwa kwa Sarcoma mukamamwa mankhwala a khansa ya Doxorubicin, ndipo zakudya zina ndi zowonjezera sizovomerezeka.

Magwero ngati cBioPortal ndipo ena ambiri amapereka deta yosadziwika ya odwala omwe ali ndi chiwerengero cha anthu omwe amachokera ku mayesero a zachipatala pa zizindikiro zonse za khansa. Izi zili ndi tsatanetsatane wa kafukufuku wazachipatala monga kukula kwa zitsanzo / kuchuluka kwa odwala, magulu azaka, jenda, fuko, chithandizo, malo otupa ndi masinthidwe aliwonse.

TP53, PDGFRB, PIK3R1, PI4KA ndi ERCC2 ndi omwe ali pamwamba pa jini za Sarcoma. TP53 imanenedwa mu 5.5% ya odwala oyimira m'mayesero onse azachipatala. Ndipo PDGFRB imanenedwa mu 2.8%. Deta yophatikizidwa ya odwala imaphimba zaka kuyambira 7 mpaka 61. 47.3 % ya deta ya odwala amadziwika kuti ndi amuna. Biology ya Sarcoma pamodzi ndi ma genetics omwe amafotokozedwa palimodzi amafotokozera kuchuluka kwazomwe zimayimiridwa ndi njira zama biochemical za khansa iyi. Ngati chibadwa cha khansa ya munthu kapena majini omwe amathandizira pachiwopsezo amadziwikanso ndiye kuti ayenera kugwiritsidwanso ntchito pakusintha zakudya.

ZOSANKHA ZA KALERE ZIYENERA KUGWIRITSA NTCHITO NDI SIZINI YA KANSA YA MUNTHU ALIYENSE.

Zakudya ndi Zowonjezera za Sarcoma

Kwa Odwala Khansa

Odwala khansa omwe ali ndi chithandizo chamankhwala kapena ochepetsa chithandizo chamankhwala amayenera kupanga zisankho pazakudya ndi zowonjezera - pazakudya zopatsa thanzi, kuthana ndi zovuta zilizonse komanso kuwongolera kasamalidwe ka khansa. Zakudya zonse zozikidwa pamasamba sizofanana ndipo kusankha ndikuyika patsogolo zakudya zomwe zimasankhidwa payekhapayekha komanso zomwe zimasinthidwa kuti zigwiritsidwe ntchito ndi khansa ndizofunikira komanso zovuta. Nazi zitsanzo zopereka malangizo opangira zisankho za kadyedwe.

Sankhani Masamba NEW ZEALAND SPINACH kapena SPINACH?

Masamba a New Zealand Sipinachi ali ndi zinthu zambiri zogwira ntchito kapena bioactives monga Curcumin, Apigenin, Lycopene, Formononetin, Beta-sitosterol. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Kukonza kwa DNA, Kutupa, Kuzindikiritsa kwa MAPK ndi MYC Signaling ndi ena. New Zealand Sipinachi amalangizidwa kuti agwiritse ntchito Sarcoma pamene chithandizo cha khansa chopitilira ndi Doxorubicin. Izi ndichifukwa choti Sipinachi ya ku New Zealand imasintha njira za biochemical zomwe zanenedwa mwasayansi kuti zidziwitse mphamvu ya Doxorubicin.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu masamba Sipinachi ndi Curcumin, Apigenin, Formononetin, Beta-sitosterol, Quercetin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Response Heat Stress Response ndi Oxidative Stress ndi ena. Sipinachi sizovomerezeka kwa Sarcoma pamene chithandizo cha khansa chikupitirirabe ndi Doxorubicin chifukwa chimasintha njira zomwe zimapangitsa kuti chithandizo cha khansa chisamve kapena kuyankha.

MASANGALA NEW ZEALAND SPINACH AMAKONZEDWA PA SPINACH YA Sarcoma NDI MANKHWALA A Doxorubicin.

Sankhani Zipatso FRENCH PLANTAIN kapena BLACK ELDERBERRY?

Zipatso za French Plantain zili ndi zinthu zambiri zogwira ntchito kapena bioactives monga Curcumin, Apigenin, Formononetin, Beta-sitosterol, Quercetin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Kukonza kwa DNA, Kutupa, MAPK Signaling ndi MYC Signaling ndi ena. French Plantain akulimbikitsidwa kuti agwiritse ntchito Sarcoma pamene chithandizo cha khansa chopitilira ndi Doxorubicin. Izi zili choncho chifukwa French Plantain imasintha njira za biochemical zomwe zanenedwa mwasayansi kuti zidziwitse mphamvu ya Doxorubicin.

Zina mwazinthu zomwe zimagwira ntchito kapena ma bioactive mu zipatso za Black Elderberry ndi Curcumin, Apigenin, Lycopene, Formononetin, Beta-sitosterol. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Oxidative Stress ndi Oncogenic Cancer Epigenetics ndi ena. Black Elderberry ndiyosavomerezeka kwa Sarcoma pamene chithandizo cha khansa chikupitilira ndi Doxorubicin chifukwa chimasintha njira zama biochemical zomwe zimapangitsa kuti chithandizo cha khansa zisamve kapena kuyankha.

FRUIT FRENCH PLANTAIN AMALANGIZIDWA PA BLACK ELDERBERRY WA Sarcoma NDI Mchiritsi wa Doxorubicin.

Sankhani Nut BUTTERNUT kapena CHESTNUT?

Butternut imakhala ndi zinthu zambiri zogwira ntchito kapena bioactives monga Curcumin, Apigenin, Lycopene, Formononetin, Beta-sitosterol. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Kukonza kwa DNA, Kutupa, Kuzindikiritsa kwa MAPK ndi MYC Signaling ndi ena. Butternut amalimbikitsidwa pa Sarcoma pamene chithandizo cha khansa chopitilira ndi Doxorubicin. Izi ndichifukwa choti Butternut imasintha njira zama biochemical zomwe zanenedwa mwasayansi kuti zidziwitse mphamvu ya Doxorubicin.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu Chestnut ndi Curcumin, Apigenin, Lycopene, Formononetin, Beta-sitosterol. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Epithelial kupita ku Mesenchymal Transition, WNT Beta Catenin Signaling ndi Oxidative Stress ndi ena. Chestnut ndiyosavomerezeka kwa Sarcoma pamene chithandizo cha khansa chikuchitika ndi Doxorubicin chifukwa imasintha njira za biochemical zomwe zimapangitsa kuti chithandizo cha khansa zisamve kapena kuyankha.

BUTTERNUT AMADALITSIDWA PA CHESTNUT PA Sarcoma NDI MACHIRITSO Doxorubicin.

Kwa Anthu Amene Ali ndi Genetic Risk of Cancer

Funso lofunsidwa ndi anthu omwe ali ndi chiopsezo cha majini a Sarcoma kapena mbiri ya banja ndi "Kodi Ndiyenera Kudya Chiyani Mosiyana ndi Kale?" ndi momwe angasankhire zakudya ndi zowonjezera kuti athe kuthana ndi kuopsa kwa matendawa. Popeza pachiwopsezo cha khansa palibe chomwe chingachitike pankhani ya chithandizo - zosankha zazakudya ndi zowonjezera zimakhala zofunika komanso chimodzi mwazinthu zochepa zomwe zingatheke. Zakudya zonse zochokera ku zomera sizofanana ndipo zimatengera chibadwa chodziwika ndi siginecha ya njira - zosankha za zakudya ndi zowonjezera ziyenera kukhala zaumwini.

Sankhani Masamba GIANT BUTTERBUR kapena GARLAND CHRYSANTHEMUM?

Masamba a Giant Butterbur ali ndi zinthu zambiri zogwira ntchito kapena bioactives monga Apigenin, Curcumin, Lycopene, Lupeol, Daidzein. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Cell Cycle, Stem Cell Signaling, P53 Signaling ndi MAPK Signaling ndi ena. Giant Butterbur ikulimbikitsidwa kuti ikhale pachiwopsezo cha Sarcoma pomwe chiwopsezo chokhudzana ndi majini ndi ERCC2. Izi ndichifukwa choti Giant Butterbur imakulitsa njira za biochemical zomwe zimatsutsana ndi oyendetsa siginecha ake.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu masamba a Garland Chrysanthemum ndi Apigenin, Curcumin, Lupeol, Daidzein, Formononetin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Stem Cell Signaling ndi MAPK Signaling ndi ena. Garland Chrysanthemum sichivomerezedwa ngati chiopsezo cha Sarcoma pamene chiwopsezo cha chibadwa ndi ERCC2 chifukwa chimawonjezera njira zake.

MANKHWALA WABWINO WA MASWERERO AMADALITSIDWA PA GARLAND CHRYSANTHEMUM PA ERCC2 GENETIC RISK WA KANSA.

Sankhani Chipatso NANCE kapena PUMMELO?

Zipatso za Nance zili ndi zinthu zambiri zogwira ntchito kapena bioactives monga Apigenin, Curcumin, Lupeol, Daidzein, Formononetin. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Cell Cycle, Stem Cell Signaling, P53 Signaling ndi MAPK Signaling ndi ena. Nance akulimbikitsidwa pachiwopsezo cha Sarcoma pomwe chiwopsezo chokhudzana ndi majini ndi ERCC2. Izi ndichifukwa choti Nance amawonjezera njira za biochemical zomwe zimatsutsana ndi oyendetsa siginecha ake.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu chipatso Pummelo ndi Apigenin, Curcumin, Quercetin, Lycopene, Lupeol. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga kukonza DNA ndi Ma cell Cycle Checkpoints ndi ena. Pummelo sivomerezedwa ngati chiopsezo cha Sarcoma pamene chiwopsezo chokhudzana ndi majini ndi ERCC2 chifukwa chimawonjezera njira zake.

FRUIT NANCE AKUKONZEDWA PA PUMMELO PA ERCC2 GENETIC RISK OF CANCER.

Sankhani Nut COMMON HAZELNUT kapena EUROPEAN CHESTNUT?

Hazelnut Wamba imakhala ndi zinthu zambiri zogwira ntchito kapena bioactives monga Curcumin, Quercetin, Lycopene, Lupeol, Daidzein. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga Cell Cycle, MAPK Signaling, P53 Signaling ndi Angiogenesis ndi ena. Mtedza Wamba wa Hazelnut umalimbikitsidwa kuti ukhale pachiwopsezo cha Sarcoma pomwe chiwopsezo cha ma genetic ndi ERCC2. Izi ndichifukwa choti Common Hazelnut imachulukitsa njira zama biochemical zomwe zimatsutsana ndi madalaivala ake.

Zina mwazinthu zomwe zimagwira ntchito kapena bioactives mu European Chestnut ndi Apigenin, Ellagic Acid, Curcumin, Quercetin, Lupeol. Zosakaniza zogwira izi zimagwiritsa ntchito njira zosiyanasiyana zama biochemical monga kukonza DNA ndi Stem Cell Signaling ndi ena. European Chestnut sivomerezedwa ngati chiopsezo cha Sarcoma pamene chiwopsezo chokhudzana ndi majini ndi ERCC2 chifukwa chimawonjezera njira zake.

COMMON HAZELNUT AMAKANGALIKIDWA PA CHESTNUT YA KU ULAYA PA ERCC2 GENETIC RISK OF CANCER.

Pomaliza

Zakudya ndi Zowonjezera zomwe zasankhidwa ndizofunikira kwambiri pa khansa monga Sarcoma. Odwala a Sarcoma komanso anthu omwe ali pachiwopsezo cha majini nthawi zonse amakhala ndi funso ili: "Ndi zakudya ziti ndi zakudya zowonjezera zomwe zimandilimbikitsa komanso zomwe sizili?" Pali chikhulupiliro chofala chomwe ndi lingaliro lolakwika kuti zakudya zonse zokhala ndi mbewu zitha kukhala zopindulitsa kapena ayi koma sizingakhale zovulaza. Zakudya zina ndi zowonjezera zimatha kusokoneza chithandizo cha khansa kapena kulimbikitsa madalaivala a khansa.

Pali mitundu yosiyanasiyana yazizindikiro za khansa monga Sarcoma, iliyonse ili ndi chibadwa chosiyana cha chotupa chokhala ndi ma genomic osiyanasiyana pamunthu aliyense. Kuphatikiza apo, chithandizo chilichonse cha khansa ndi chemotherapy chili ndi njira yapadera yochitira. Chakudya chilichonse monga New Zealand Sipinachi chimakhala ndi ma bioactive osiyanasiyana mosiyanasiyana, omwe amakhudza njira zosiyanasiyana zama biochemical. Tanthauzo la zakudya zamunthu payekhapayekha ndi malingaliro amunthu payekhapayekha pazowonetsa khansa, machiritso, ma genetic, moyo ndi zina. Zosankha zokhudzana ndi thanzi la khansa zimafuna kudziwa za biology ya khansa, sayansi yazakudya komanso kumvetsetsa kwamankhwala osiyanasiyana a chemotherapy. Pomaliza pakakhala kusintha kwamankhwala kapena ma genomics atsopano azindikirika - kusintha kwa zakudya kumafunika kuunikanso.

Njira yothetsera makonda a addon imapangitsa kupanga chisankho kukhala kosavuta ndikuchotsa malingaliro onse poyankha funso, "Ndi zakudya ziti zomwe ndiyenera kusankha kapena kusasankha za Sarcoma?". Gulu la addon lamitundu yambiri limaphatikizapo madokotala a khansa, asayansi azachipatala, akatswiri opanga mapulogalamu ndi asayansi a data.

Zothandizira

• Mixed Kunga Msk 2022
• Zosintha zamtundu wa subtype-specific genomic zimatanthawuza mipherezero yatsopano yochizira minofu yofewa ya sarcoma.
• L-Ascorbic Acid Imalepheretsa Kukula kwa Khansa ya M'mawere Poyambitsa IRE/JNK/CHOP-Related Endoplasmic Reticulum Stress-Mediated p62/SQSTM1 Kuchulukana mu Nucleus.
• Kulimbikitsa kukula kwa maselo amtundu wa pulmonary adenocarcinoma ndi maselo ang'onoang'ono a epithelial airway ndi beta-carotene kudzera mu activation ya cAMP, PKA, CREB ndi ERK1/2.
• Kuwongolera koyipa kwa transducer ya ma signal ndi activator ya transcript-3 signing cascade ndi lupeol imalepheretsa kukula ndikupangitsa apoptosis mu cell hepatocellular carcinoma.
• https://my.clevelandclinic.org/health/diseases/21732-adult-soft-tissue-sarcoma